MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'European Journal of Surgical Oncology' source. Sat, 20 Mar 2010 13:50:29 +0100 http://www.medworm.com/index.php?rid=3194974&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309005551%2Fabstract%3Frss%3Dyes Membership of ESSO includes the yearly subscription to the EJSO and entitles the members to a significant discount on the registration rates of major congresses including the biennial ESSO Congress in even years and the ECCO-ESMO Congress in odd years as well as courses designed or supported by ESSO. Further, it gives access to the ESSO fellowship scheme. Last but not least, members of ESSO are part of an international professional network of more than 1.800 individuals. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3194974 Fri, 22 Jan 2010 13:47:58 +0100 3194974 http://www.medworm.com/index.php?rid=3194973&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS074879830900554X%2Fabstract%3Frss%3Dyes 7th European Breast Cancer Conference 24–27 March 2010, Barcelona, Spain (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3194973 Fri, 22 Jan 2010 13:47:58 +0100 3194973 http://www.medworm.com/index.php?rid=3194972&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309004727%2Fabstract%3Frss%3Dyes Abstract: Purpose: The aim of the current study was to investigate the role of F-18 FDG PET/CT in the detection and prediction of local recurrence of maxillary sinus cancer.Methods: Retrospectively, we analyzed F-18 FDG PET/CT images of maxillary sinus cancer patients for the surveillance after treatment. Twenty-two consecutive patients with maxillary sinus cancer, who underwent maxillectomy followed by adjuvant radiation treatment, were included in the study. F-18 FDG PET/CT images were analyzed visually and quantitatively.Results: The median age of the patients included in the current study population was 54.5 years (range, 35–78). Seven patients (29.1%) had local recurrent diseases. Recurrent diseases show statistically significant higher values in SUVmax (recurrent: 5.09 ± 3.3, no... European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3194972 Fri, 22 Jan 2010 13:47:58 +0100 3194972 http://www.medworm.com/index.php?rid=3194971&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309002261%2Fabstract%3Frss%3Dyes Conclusion: The surgical resection of small tumors or vascular lesions within the Meckel's cave or cavernous sinus is facilitated by neuronavigational guidance with sufficient intraoperative reliability and safety. In consideration of well known anatomical landmarks, targeted entry into the cavernous sinus or Meckel's cave directed by neuronavigation enables a tailored approach for microsurgical resection. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3194971 Fri, 22 Jan 2010 13:47:58 +0100 3194971 http://www.medworm.com/index.php?rid=3194970&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309002315%2Fabstract%3Frss%3Dyes Conclusion: The study showed that peptidomics technology is able to identify possible biomarkers of neoplastic CNS disease. It remains to be determined if the identified elevated CSF peptides are specific for GBM. With regard to GBM, however, the more important role of CSF peptide biomarkers than aiding initial diagnosis might be early recognition of disease recurrence or monitoring of efficacy of adjuvant therapy protocols. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3194970 Fri, 22 Jan 2010 13:47:58 +0100 3194970 http://www.medworm.com/index.php?rid=3194969&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309004089%2Fabstract%3Frss%3Dyes Conclusion: The EC provided superior usability and visualization potential compared to standard rigid endoscopes with fixed angulation. It combines the ergonomic and safety advantage of not having to insert endoscopes with different angles with the opportunity to “scan” the surgical field with a variable angle of 0°–120° within one plane of view. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3194969 Fri, 22 Jan 2010 13:47:57 +0100 3194969 http://www.medworm.com/index.php?rid=3194968&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309004429%2Fabstract%3Frss%3Dyes Conclusions: In this preliminary study, MRI was superior to FDG-PET for staging of liver metastases from uveal melanoma. Although miliary disease was suggested by MRI in some cases, preoperative confirmation remains imperfect. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3194968 Fri, 22 Jan 2010 13:47:57 +0100 3194968 http://www.medworm.com/index.php?rid=3194967&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309005009%2Fabstract%3Frss%3Dyes Conclusions: Severe ischemia due to prolonged portal triad clamping during hepatic resection for colorectal liver metastases appears to be associated with decreased TTLiR. Further research remains necessary to determine the causative effect of prolonged vascular clamping on liver tumour recurrence. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3194967 Fri, 22 Jan 2010 13:47:57 +0100 3194967 http://www.medworm.com/index.php?rid=3194966&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309001802%2Fabstract%3Frss%3Dyes Conclusions: Positive margins for invasive carcinoma seem to be a strong predictor for local recurrence in particular for women≤50-years. Our study showed grade 3 and tumour size to be strong predictors of DMFS, DFS, and DSS. Margin status was not. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3194966 Fri, 22 Jan 2010 13:47:57 +0100 3194966 http://www.medworm.com/index.php?rid=3194965&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309004636%2Fabstract%3Frss%3Dyes Conclusion: ADH diagnosed by vacuum-assisted breast biopsy frequently corresponds to cancer on open surgical biopsy. Surgical excision of all breast lesions containing atypical hyperplasia on percutaneous biopsy can be recommended. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3194965 Fri, 22 Jan 2010 13:47:57 +0100 3194965 http://www.medworm.com/index.php?rid=3194964&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309004818%2Fabstract%3Frss%3Dyes Conclusion: This study has shown that 125I seed localization is a novel and highly successful technique in localizing the tumour bed in patients who receive neo-adjuvant chemotherapy for breast cancer leading to a high percentage of radical margins in case of breast-conserving surgery. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3194964 Fri, 22 Jan 2010 13:47:57 +0100 3194964 http://www.medworm.com/index.php?rid=3194963&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309004119%2Fabstract%3Frss%3Dyes Conclusion: The D25 E variant is the most prevalent E6 genomic variant in Hubei, China. The presence of HPV 16 E6 variant in cervical intraepithelial neoplasia (CIN) lesions may serve as a useful predictor of clinical outcome of the disease. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3194963 Fri, 22 Jan 2010 13:47:56 +0100 3194963 http://www.medworm.com/index.php?rid=3194962&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309004661%2Fabstract%3Frss%3Dyes Abstract: Aims: Although the positive lymph node (LN) metastasis in patients with thoracic esophageal squamous cell carcinoma carcinoma (SCC) has been reported to be a risk factor to reduce long-term survival, only a few studies have so far evaluated the lymph node metastasis among this group of patients. The purpose of this study was to evaluate the impact of lymph node positivity and ratio on survival of esophageal SCC.Methods: All patients undergoing esophagectomy at the Forth Hospital of Hebei Medical University between January 1986 and December 2002 were reviewed. Survival curves were estimated using the Kaplan-Meier method.Results: Of 1325 patients with invasive cancer, had squamous cell cancer of the esophagus. Median overall survival (OS) of the entire group was 36.7 months and 5-y... European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3194962 Fri, 22 Jan 2010 13:47:56 +0100 3194962 http://www.medworm.com/index.php?rid=3194961&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309004697%2Fabstract%3Frss%3Dyes Conclusions: Potentially curative gastrectomy for cancer has a detrimental impact on HRQL that mostly recovers in patients surviving some 2years. Patients who die within 2years may experience limited postoperative recovery. It is recommended that patients receive HRQL information about the outcomes of surgery for gastric cancer. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3194961 Fri, 22 Jan 2010 13:47:56 +0100 3194961 http://www.medworm.com/index.php?rid=3194960&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309004739%2Fabstract%3Frss%3Dyes Abstract: Background: Centralisation of surgical treatment of cancer has resulted in improved outcomes. We aimed to determine evidence of benefit for specialised management of upper gastrointestinal cancer in high-volume centres in Scotland.Methods: Discharge records of patients undergoing oesophagectomy, gastrectomy, hepatectomy or pancreatectomy between 1982 and 2003 were identified. Hospital data were analysed on a year-by-year basis to derive ‘hospital-years’. Hospital-years were divided into quartiles by volume, and were analysed with regard to in-hospital mortality during the operative admission [Chi-square test (χ2) and Chi-square test for trend (χ2trend)].Results: 10,625 patients and 982 in-hospital deaths were included. In-hospital mortality rates declined during the study p... European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3194960 Fri, 22 Jan 2010 13:47:56 +0100 3194960 http://www.medworm.com/index.php?rid=3194959&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309001747%2Fabstract%3Frss%3Dyes Abstract: Aim: The aim was to investigate whether a set of measures directed at increasing lymph node (LN) detection among colon cancer patients led to clinically relevant changes in LN detection rate.Methods: Data of all patients with curative colon cancer (pTany Nany M0) diagnosed in 1999–2007 whose resection specimens were evaluated by the Institute for Pathology and Medical Microbiology in Eindhoven (n=1501) were included. Feedback to specialists, increased fixation time, and ex-vivo injection of the specimen with Patent blue V dye were used to increase LN detection rate. Trends in the proportion of patients with insufficient LNs examined were investigated; moreover, the Patent blue-stained patients (n=86) were compared with a group of unstained patients (n=84). Based on the decrease... European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3194959 Fri, 22 Jan 2010 13:47:56 +0100 3194959 http://www.medworm.com/index.php?rid=3194958&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309001991%2Fabstract%3Frss%3Dyes Conclusions: Ex vivo SLN mapping after colorectal cancer surgery is technically feasible with a high identification rate. Tumor size and stage, rectal involvement and a mucinous histology seem to interfere with the reliability of SLN staging. It is mandatory to standardize the procedure and selection criteria in order to deal with the question of the reliability of SLN mapping in colorectal cancer. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3194958 Fri, 22 Jan 2010 13:47:56 +0100 3194958 http://www.medworm.com/index.php?rid=3194957&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS074879830900225X%2Fabstract%3Frss%3Dyes Conclusions: This study demonstrates no differences in the detected circulating numbers of tumor cells at different stages of surgical intervention. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3194957 Fri, 22 Jan 2010 13:47:56 +0100 3194957 http://www.medworm.com/index.php?rid=3194956&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309004405%2Fabstract%3Frss%3Dyes The objective of this study was to find out the effects of anastomotic leakage (AL) following resection of colon cancer upon perioperative outcome and long-term oncological result.Patients and methods: Using the database of a country-wide quality assurance study “Quality Assurance in Primary Colorectal Carcinoma” we analysed the data from the complete sub-population of 844 patients who had AL after resection of colon cancer. These were compared with corresponding data from 27 427 similar patients without AL. Hospital mortality, AL-associated post-operative morbidity and long-term outcome were investigated.Results: Hospital mortality after AL was 18.6%, compared with 2.6% for patients without AI. AL-related secondary complications occurred in 62.7% cases, while patients without AL had... European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3194956 Fri, 22 Jan 2010 13:47:55 +0100 3194956 http://www.medworm.com/index.php?rid=3194955&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309004685%2Fabstract%3Frss%3Dyes Conclusion: Breast MRI can result in additional detection of otherwise occult lesions in occult breast cancer. Because of low specificity of malignant lesion detection by breast MRI, lesions should be histologically confirmed. This can be achieved either by MRI or ultrasound guided biopsy, as long as all MRI detected lesions are histologically checked. Routine application of breast MRI in occult breast cancer may also alter locoregional treatment by offering the possibility of breast conserving surgery in one thirds of patients. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3194955 Fri, 22 Jan 2010 13:47:55 +0100 3194955 http://www.medworm.com/index.php?rid=3194954&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309004090%2Fabstract%3Frss%3Dyes Few solid malignancies could have undergone such a major change in diagnosis and management in recent years as adenocarcinoma of the rectum. It is truly a multi-disciplinary malignancy which has benefited from a pleasing improvement in prognosis over the last 20 years. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3194954 Fri, 22 Jan 2010 13:47:55 +0100 3194954 http://www.medworm.com/index.php?rid=3194953&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309005514%2Fabstract%3Frss%3Dyes (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3194953 Fri, 22 Jan 2010 13:47:55 +0100 3194953 http://www.medworm.com/index.php?rid=3154300&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309005277%2Fabstract%3Frss%3Dyes Membership of ESSO includes the yearly subscription to the EJSO and entitles the members to a significant discount on the registration rates of major congresses including the biennial ESSO Congress in even years and the ECCO-ESMO Congress in odd years as well as courses designed or supported by ESSO. Further, it gives access to the ESSO fellowship scheme. Last but not least, members of ESSO are part of an international professional network of more than 1.800 individuals. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3154300 Fri, 01 Jan 2010 00:00:00 +0100 3154300 http://www.medworm.com/index.php?rid=3154299&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309005265%2Fabstract%3Frss%3Dyes 7th European Breast Cancer Conference 24–27 March 2010, Barcelona, Spain (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3154299 Fri, 01 Jan 2010 00:00:00 +0100 3154299 http://www.medworm.com/index.php?rid=3154298&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309004399%2Fabstract%3Frss%3Dyes Parathyroid carcinoma is an uncommon malignancy, which occurs most commonly in patients with primary hyperparathyroidism, with an incidence of 0.5–4% in all patients surgically treated for primary hyperparathyroidism. Moreover, bilateral parathyroid carcinoma is extremely rare. Here we report the unusual case of a bilateral parathyroid carcinoma with manifestation of gastrointestinal symptoms that were relatively hidden and made an early diagnosis difficult at the onset of disease. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3154298 Fri, 01 Jan 2010 00:00:00 +0100 3154298 http://www.medworm.com/index.php?rid=3154297&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309001036%2Fabstract%3Frss%3Dyes Massive localized lymphedema (MLL) is a condition most commonly found in the extremities of morbidly obese patients. It is thought to be caused by localized lymphatic obstruction secondary to anatomic distortion from obesity. It mimics malignant lesions such as liposarcoma. Proper management of these lesions is challenging, and therapeutic regimens remain to be established. We will now describe a case of MLL, discuss the likely etiologies of the disease, and explore the factors that must be taken into consideration in determining treatment options. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3154297 Fri, 01 Jan 2010 00:00:00 +0100 3154297 http://www.medworm.com/index.php?rid=3154296&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309002327%2Fabstract%3Frss%3Dyes Conclusion: The most frequent location of fracture Port-A was in proximal part – anastomosis between injection port and catheter. The cause of easily fracture may be associated with pinch-off-syndrome and design of Port-A. This kind of fracture could be prevented by cut-down method and fixed one stitch in proximal part. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3154296 Fri, 01 Jan 2010 00:00:00 +0100 3154296 http://www.medworm.com/index.php?rid=3154295&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309001632%2Fabstract%3Frss%3Dyes Conclusions: In this population-based study in patients treated for extremity STS, the proportion of patients operated without preoperative pathology evaluation was high. In the remaining patients an incisional biopsy was still the most commonly performed technique with the highest yield. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3154295 Fri, 01 Jan 2010 00:00:00 +0100 3154295 http://www.medworm.com/index.php?rid=3154294&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309002285%2Fabstract%3Frss%3Dyes Conclusion: After wide surgical resection of a DFSP or DFSP-FS, or an R1 resection combined with adjuvant radiotherapy the risk of local recurrence is extremely low. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3154294 Fri, 01 Jan 2010 00:00:00 +0100 3154294 http://www.medworm.com/index.php?rid=3154293&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309004077%2Fabstract%3Frss%3Dyes Conclusion: Low recurrence rates can be achieved with the use of radiation therapy alone in selected cases. Patients with a metabolic response (decrease) to radiotherapy may be treated with a non-surgical approach. Surgery might be considered in patients with a poor metabolic response to radiotherapy. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3154293 Fri, 01 Jan 2010 00:00:00 +0100 3154293 http://www.medworm.com/index.php?rid=3154292&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309004351%2Fabstract%3Frss%3Dyes Conclusions: Free flaps are useful and reliable in the treatment of patients with STS of the upper extremity. Without microvascular reconstruction limb salvage would have been impossible in these patients. Oncological outcome is comparable to other extremity STS patients and upper extremity function is acceptable. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3154292 Fri, 01 Jan 2010 00:00:00 +0100 3154292 http://www.medworm.com/index.php?rid=3154291&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309001759%2Fabstract%3Frss%3Dyes Discussion: Our data indicate that HERG1, but not CEA, CK19 or CK20, is a highly sensitive and reliable tumor biomarker that may constitute a novel molecular target for tumor treatment. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3154291 Fri, 01 Jan 2010 00:00:00 +0100 3154291 http://www.medworm.com/index.php?rid=3154290&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309004375%2Fabstract%3Frss%3Dyes Conclusions: Primary anastomosis for emergency left colon carcinoma obstruction should only be regarded as indicated in cases where the risk profile is favourable. Our results suggest that in advanced obstruction and in high-risk cases Hartmann's procedure should be used. A protective stoma did not appear to confer any advantage. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3154290 Fri, 01 Jan 2010 00:00:00 +0100 3154290 http://www.medworm.com/index.php?rid=3154289&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309004958%2Fabstract%3Frss%3Dyes Abstract: Aim: Management of patients with irresectable stage IV colorectal cancer is controversial. Since 2000, we have favoured primary chemotherapy with stent insertion in case of obstructive tumor. Our aim was to report the results of this strategy in an unselected consecutive series of patients.Patients and methods: From 2000 to 2007, 68 of 115 consecutive patients admitted with stage IV colorectal cancer were considered irresectable. Data were collected prospectively. Feasibility and outcomes were analysed in an intention to treat basis.Results: Of 68 patients, 37 received the intended primary chemotherapy, with stent insertion in 19, 13 required surgery as initial management and 18 patients received supportive care only. Twelve patients in the primary chemotherapy group developed lo... European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3154289 Fri, 01 Jan 2010 00:00:00 +0100 3154289 http://www.medworm.com/index.php?rid=3154288&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS074879830900465X%2Fabstract%3Frss%3Dyes Abstract: Background: Hepatic steatosis (HS) is as an independent risk factor for morbidity and mortality post-hepatectomy. Recent studies report significant correlation between chemotherapy (now frequently employed pre-hepatectomy for colorectal liver metastases (CRLM)), HS and steatohepatitis. Furthermore, raised body mass index (BMI) predisposes to HS. However, no previous study has analysed the effect of HS on long-term survival.Method: A retrospective analysis of a prospective consecutive cohort of 102 patients undergoing hepatectomy with 60 months follow-up data was performed. Resection specimens were examined histologically and the degree of steatosis graded accordingly. The data was compared to BMIs and other clinical characteristics. Statistical analyses included log-rank, conting... European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3154288 Fri, 01 Jan 2010 00:00:00 +0100 3154288 http://www.medworm.com/index.php?rid=3154287&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309001620%2Fabstract%3Frss%3Dyes Abstract: Introduction: The optimal size of clear liver resection margin width in patients with colorectal liver metastases (CRLM) remains controversial. The aim of this study was to investigate the effects of margin width on long-term survival after liver resection for CRLM with a policy of standard neo-adjuvant chemotherapy.Methods: Consecutive patients (n=238) who underwent liver resection for CRLM were included over a ten-year period. All patients with synchronous or early (1cm resection margins. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3154287 Fri, 01 Jan 2010 00:00:00 +0100 3154287 http://www.medworm.com/index.php?rid=3154286&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309004107%2Fabstract%3Frss%3Dyes Conclusion: Our study shows that CEUS has a high sensitivity and specificity for characterising focal liver lesions. CEUS has advantages over CT and MRI of a high degree of safety, good patient tolerance and often availability at the time of initial detection. We therefore suggest that CEUS should be used as the initial study in the characterisation of FLLs. The study should be followed, as appropriate, by CT and MRI or PET studies. Biopsy, with its risks of tumour seeding and false negative results should only be considered after review of the imaging studies and full MDT discussion. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3154286 Fri, 01 Jan 2010 00:00:00 +0100 3154286 http://www.medworm.com/index.php?rid=3154285&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309001760%2Fabstract%3Frss%3Dyes Conclusion: Despite a significantly higher detection rate for hepatic metastases, CTAP has no added value in the therapeutic stratification in candidates for resection of hepatic metastases of colorectal cancer. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3154285 Fri, 01 Jan 2010 00:00:00 +0100 3154285 http://www.medworm.com/index.php?rid=3154284&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309001723%2Fabstract%3Frss%3Dyes Conclusions: The MSKCC, Cambridge, and Stanford nomograms were good discriminators of NSLNM in SLN positive BC patients in this study. A newly created formula in this study needs to be validated in prospective studies in different patient populations. A nomogram to predict NSLNM in patients with positive SLN biopsy developed at one institution should be used with caution. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3154284 Fri, 01 Jan 2010 00:00:00 +0100 3154284 http://www.medworm.com/index.php?rid=3154283&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309004995%2Fabstract%3Frss%3Dyes Conclusions: SLNB has a high identification rate and modest false-negative rate in LABC patients who became clinically axillary node negative after NAC. Residual tumor size and nodal status before NAC affect SLNB accuracy. Additional involvement of non-SLN(s) increases with the presence of multifocal/multicentric tumors, lymphovascular invasion, residual tumor size >2cm, and extra-sentinel node extension. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3154283 Fri, 01 Jan 2010 00:00:00 +0100 3154283 http://www.medworm.com/index.php?rid=3154282&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309004673%2Fabstract%3Frss%3Dyes Conclusion: Simplified models and algorithms can predict IMN status. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3154282 Fri, 01 Jan 2010 00:00:00 +0100 3154282 http://www.medworm.com/index.php?rid=3154281&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309004983%2Fabstract%3Frss%3Dyes Abstract: Aims and background: Improved visualization of surgical targets inside of the patient helps to improve radical resection of the tumor while sparing healthy surrounding tissue. In order to achieve an image, optical contrast must be generated by properties intrinsic to the tissue, or require the attachment of special visualization labels to the tumor. In this overview the current status of the clinical use of fluorescent dyes and probes are reviewed.Methods: In this review, all experimental and clinical studies concerning fluorescent imaging were included. In addition, in the search for the optimal fluorescent imaging modality, all characteristics of a fluorescent dye were described.Findings and conclusions: Although the technique of imaging through fluorescence sounds promising an... European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3154281 Fri, 01 Jan 2010 00:00:00 +0100 3154281 http://www.medworm.com/index.php?rid=3154280&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309004740%2Fabstract%3Frss%3Dyes The Editor-in-Chief, Associate Editors and Editorial Team of the EJSO would like to thank the following people who acted as peer-reviewers in 2009. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3154280 Fri, 01 Jan 2010 00:00:00 +0100 3154280 http://www.medworm.com/index.php?rid=3154279&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309004193%2Fabstract%3Frss%3Dyes As the technologies of the Web have advanced from the earliest formats to its present utility and pervasiveness, so we have sought to advise and inform our EJSO readers in articles and editorials on its uses in medical research, education and surgical oncology. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3154279 Fri, 01 Jan 2010 00:00:00 +0100 3154279 http://www.medworm.com/index.php?rid=3154278&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309005022%2Fabstract%3Frss%3Dyes After 7 extremely successful and productive years, David Rew steps down as Editor-in-Chief of EJSO. David has been an outstanding Editor and his achievements are reflected in the escalating impact factor – now standing at 2.5. At the same time, he has overseen the introduction of 12 issues per year and 120 pages per issue. During his tenure, the online readership has expanded exponentially to the extent that nearly 300,000 articles are downloaded per year. These data provide some indication of David's enormous commitment and dedication during his time as Editor. On behalf of the entire readership, I would like to thank him most sincerely and congratulate him on his achievements. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3154278 Fri, 01 Jan 2010 00:00:00 +0100 3154278 http://www.medworm.com/index.php?rid=3154277&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS074879830900523X%2Fabstract%3Frss%3Dyes (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=3154277 Fri, 01 Jan 2010 00:00:00 +0100 3154277 http://www.medworm.com/index.php?rid=2990289&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309004880%2Fabstract%3Frss%3Dyes (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2990289 Sat, 14 Nov 2009 13:46:42 +0100 2990289 http://www.medworm.com/index.php?rid=2990288&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309004879%2Fabstract%3Frss%3Dyes (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2990288 Sat, 14 Nov 2009 13:46:42 +0100 2990288 http://www.medworm.com/index.php?rid=2990287&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309001954%2Fabstract%3Frss%3Dyes We read with interest the paper from Bats et al., published in the March 2009 issue of this journal. Our letter has two goals: (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2990287 Sat, 14 Nov 2009 13:46:42 +0100 2990287 http://www.medworm.com/index.php?rid=2990286&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309002078%2Fabstract%3Frss%3Dyes Conclusions: The number of levels with pathologic lymph node, the site of primary tumor and the level of tumor invasion are decisive risk factors in determining the development of DM in head and neck SCC patients. Patients with multilevel nodal involvement in neck, with laryngeal and hypopharyngeal carcinomas, and patients with primary tumor invasion into muscular, bone or cartilage have the highest risk of developing DM. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2990286 Sat, 14 Nov 2009 13:46:41 +0100 2990286 http://www.medworm.com/index.php?rid=2990285&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309001784%2Fabstract%3Frss%3Dyes Conclusion: Intralesional curettage is an effective treatment strategy for low-grade intramedullary chondrosarcoma of long bones, with excellent oncological and functional results. Careful case selection with stringent clinical and radiographic follow-up is recommended. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2990285 Sat, 14 Nov 2009 13:46:41 +0100 2990285 http://www.medworm.com/index.php?rid=2990284&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309002297%2Fabstract%3Frss%3Dyes Conclusions: In absence of randomized controlled trial which are difficult to design and conduct, the results of present study shows that mandibular conservation may be carried out, even in presence of involved mandible if negative resection margins could be achieved. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2990284 Sat, 14 Nov 2009 13:46:41 +0100 2990284 http://www.medworm.com/index.php?rid=2990283&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309001772%2Fabstract%3Frss%3Dyes Conclusions: This is the only study in recent 2 decades to evaluate the necessity of synchronous adrenalectomy in treating localized upper tract urothelial carcinoma. Adrenal-sparing nephroureterectomy seems justified for clinically localized upper tract urothelial carcinoma. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2990283 Sat, 14 Nov 2009 13:46:40 +0100 2990283 http://www.medworm.com/index.php?rid=2990282&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309001619%2Fabstract%3Frss%3Dyes This study evaluates the compliance with the guidelines over time.Patients: Population-based series of 119 operated patients with a soft tissue sarcoma (STS) diagnosed in 1998–1999 (79 before implementation of new guidelines) and in 2006 (40 after implementation).Methods: Coded information regarding patient and tumour characteristics as well as (the results of) pathology review was collected from the medical patient file by two experienced data-managers.Results: Diagnostic imaging of the tumour was performed according to the guidelines in 75–100% depending on the site of the tumour (abdominal versus non-abdominal) as well as the time of diagnosis.Adherence to the guidelines with respect to invasive diagnostic procedures in patients with non-abdominal STS improved over time. A pre-opera... European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2990282 Sat, 14 Nov 2009 13:46:40 +0100 2990282 http://www.medworm.com/index.php?rid=2990281&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309001413%2Fabstract%3Frss%3Dyes Conclusions: Periacetabular endoprosthetic replacement showed an acceptable functional and oncological outcome but had a high complication rate owing, predominantly, to infection. The indication for hemipelvic prosthesis in patients with a metastatic disease must be considered seriously. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2990281 Sat, 14 Nov 2009 13:46:39 +0100 2990281 http://www.medworm.com/index.php?rid=2990280&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309002339%2Fabstract%3Frss%3Dyes Conclusions: Despite their better prognosis, younger patients with papillary thyroid cancer were referred to specialist care across significantly greater distances, regardless of their lymph node status, than older patients who have a worse prognosis. The causes underlying these age disparities in referrals to specialist care warrant further research. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2990280 Sat, 14 Nov 2009 13:46:39 +0100 2990280 http://www.medworm.com/index.php?rid=2990279&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309001966%2Fabstract%3Frss%3Dyes Conclusions: PD after CRT was safe and resected patients had interesting survival rates. However, resected patients developed metastatic disease and new neoadjuvant regimens are needed to improve the survival of these patients. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2990279 Sat, 14 Nov 2009 13:46:39 +0100 2990279 http://www.medworm.com/index.php?rid=2990278&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309002273%2Fabstract%3Frss%3Dyes Abstract: Background: An aggressive therapy comprising of cytoreductive surgery (CRS) and perioperative intraperitoneal chemotherapy (PIC) and liver resection/ablation is generally not offered to patients with both colorectal peritoneal carcinomatosis (CRPC) and liver metastases (LM) as it no longer represents a loco-regional disease. We review the outcomes of patients who underwent an aggressive treatment with a curative intent for both CRPC and LM as a prelude towards determining the suitability of this treatment.Methods: Patients with CRPC were treated with cytoreductive surgery and perioperative intraperitoneal chemotherapy in our institution. Patients with LM underwent additional treatment of liver resection/ablation. The characteristics and survival of patients with isolated CRPC and... European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2990278 Sat, 14 Nov 2009 13:46:38 +0100 2990278 http://www.medworm.com/index.php?rid=2990277&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS074879830900122X%2Fabstract%3Frss%3Dyes Abstract: Purpose: To review the current management options in inflammatory pseudotumours via analysis of ten cases from this unit the largest experience of this pathology in a Western series. To assess the medical and operative options available for this condition and the varying outcomes and the lessons learned in this unit over the time period.Results: Data from the ten cases were analysed and a comprehensive review of the published literature to date has detailed 128 case reports with 215 cases of inflammatory pseudotumour of the liver. Data analysed included patient demographics, diagnostic modalities, details of treatment and eventual outcome. The data was tabulated using an Excel spreadsheet (Microsoft® Excel 2004 for Mac 2004.Version 11.0). Categorical variables were compared usin... European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2990277 Sat, 14 Nov 2009 13:46:38 +0100 2990277 http://www.medworm.com/index.php?rid=2990276&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309001735%2Fabstract%3Frss%3Dyes Abstract: Aim: To understand the role of hypoxia in cancer progression of primary colorectal cancer and colorectal liver metastases. To look at associations of hypoxia with more aggressive phenotypes.Methods: Archival tissue was retrieved from 55 patients and tissue micro arrays were constructed using tissue from the margin and the centre of the tumour. Hypoxia markers Hif-1α, Vegf, CA-9, VHL and Glut-1 were visualised using immunohistochemical detection and quantified using semi-quantitative analysis of the digitised images. Clinical details and outcome data were retrieved by case note review and collated with hypoxia markers data in a statistical database.Results: Significantly increased expression of all markers were found at the tumour margin compared to the tumour centre, both in pr... European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2990276 Sat, 14 Nov 2009 13:46:38 +0100 2990276 http://www.medworm.com/index.php?rid=2990275&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309001607%2Fabstract%3Frss%3Dyes Abstract: Purpose: After total mesorectal excision (TME) for rectal cancer, pathology is standardized with margin status as a predictor for recurrence. This has yet to be implemented after transanal endoscopic microsurgery (TEM) and was investigated prospectively for T1 rectal adenocarcinomas.Patients and methods: Eighty patients after TEM were compared to 75 patients after TME. The study protocol included standardized pathology. TEM patients were eligible when excision margins were negative.Results: TEM was safer than TME as reflected by operating time, blood loss, hospital stay, morbidity, re-operation rate and stoma formation (all P (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2990275 Sat, 14 Nov 2009 13:46:37 +0100 2990275 http://www.medworm.com/index.php?rid=2990274&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS074879830900198X%2Fabstract%3Frss%3Dyes Conclusion: Conversion of laparoscopic colon cancer resection worsens DFS in locally advanced stage II carcinoma. There is a need to reduce the conversion rate by adequate patient selection for laparoscopic resection by experienced surgeons. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2990274 Sat, 14 Nov 2009 13:46:37 +0100 2990274 http://www.medworm.com/index.php?rid=2990273&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309002248%2Fabstract%3Frss%3Dyes Conclusion: Neoadjuvant RCT reduced the number of TILs in esophageal SCC. This was primarily seen in the centre of tumors and suggests that the effect of RCT on immunological response is located in the centre of tumors. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2990273 Sat, 14 Nov 2009 13:46:37 +0100 2990273 http://www.medworm.com/index.php?rid=2990272&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309001590%2Fabstract%3Frss%3Dyes Conclusions: Overweight and obese women may be a group that profit from mammographic screening to more than normal weight women. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2990272 Sat, 14 Nov 2009 13:46:36 +0100 2990272 http://www.medworm.com/index.php?rid=2990271&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309001188%2Fabstract%3Frss%3Dyes Abstract: Introduction: Sentinel lymph node (SLN) biopsy allows a more detailed examination of a smaller number of lymph nodes in patients with clinically node negative breast cancer. Immunohistochemistry detects small tumour burden not routinely seen on haematoxylin and eosin (H&E). The significance of such findings remains to be fully elucidated.Aim: To assess the axillary disease burden of patients in whom the sentinel lymph node biopsy was positive on immunohistochemistry and negative on H and E.Methods: An analysis of patients who underwent SLN mapping for breast cancer at St Vincent's University Hospital from January 1st, 2000 to December 31st, 2006 was conducted. All SLNs were assessed by serial H&E and IHC sections. Patients with micrometastases (0.2–2mm) underwent a completion a... European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2990271 Sat, 14 Nov 2009 13:46:36 +0100 2990271 http://www.medworm.com/index.php?rid=2990270&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309001711%2Fabstract%3Frss%3Dyes Conclusion: The NEW START recommended, combined superficial injection techniques, have high localisation rates. Pre-operative sentinel node imaging is recommended and a template for reporting is provided. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2990270 Sat, 14 Nov 2009 13:46:35 +0100 2990270 http://www.medworm.com/index.php?rid=2990269&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309001796%2Fabstract%3Frss%3Dyes Abstract: Aim: To determine the factors associated with the metastatic involvement of sentinel lymph node (SLN) biopsy in patients with early breast cancer.Study design: This was a retrospective study of patients with T1 invasive breast cancer who underwent SLN biopsy at Claudius Regaud Institute between January 2001 and September 2008.Results: 1416 patients were recruited into this study. SLN metastases were detected in 368 patients (26%). Younger age, tumor size and location, histological type, nuclear grade, and lymphovascular invasion appear to be significant risk factors of SNL involvement. In multivariate analysis, tumor size, tumor location, histological type and lymphovascular invasion are significant factors. When the tumor size is >20mm, the OR is 6.6 compared to a T1a tumor (3.1... European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2990269 Sat, 14 Nov 2009 13:46:35 +0100 2990269 http://www.medworm.com/index.php?rid=2990268&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309002340%2Fabstract%3Frss%3Dyes I am delighted to be able to report at the end of 2009 and symbolically at the end of the first decade of the 21st century that the EJSO is in excellent shape. Since its origins in the mid-1970s, the journal has progressed from a small regional subspeciality journal with a negligible Impact Factor to an Internet enabled, broadly based multi-disciplinary journal with an IF of around 2.5; a manuscript flow of around 600 per annum; an increase in publication frequency from 6 to 12 per year; a healthy rejection rate and list of manuscripts awaiting publication; and a logged full article download of some 300,000 items annually. In the past year alone, the IF has risen from 2.0 to 2.5, and this trend should continue on the basis of foundations already laid by the Editorial Team. (Source: Europe... European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2990268 Sat, 14 Nov 2009 13:46:34 +0100 2990268 http://www.medworm.com/index.php?rid=2990267&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309004843%2Fabstract%3Frss%3Dyes (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2990267 Sat, 14 Nov 2009 13:46:34 +0100 2990267 http://www.medworm.com/index.php?rid=2896012&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309004557%2Fabstract%3Frss%3Dyes (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2896012 Fri, 16 Oct 2009 12:47:11 +0100 2896012 http://www.medworm.com/index.php?rid=2896011&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309004545%2Fabstract%3Frss%3Dyes (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2896011 Fri, 16 Oct 2009 12:47:11 +0100 2896011 http://www.medworm.com/index.php?rid=2896010&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003783%2Fabstract%3Frss%3Dyes Objectives: To ensure safe, evidence based, patient care delivery Methods: Working in close liaison with the Trust's breast team, a monthly BCMS clinic was established in late 2006. Referrals are for patients with personal or family history of breast cancer seeking specialist menopause management advice. A clinical governance approach has informed service development. Multi-disciplinary menopause team patient case conferences operate at the end of each clinic. Depending on available staffing resources, a specialist breast care nurse attends each clinic. Quarterly MDT meetings with the Breast Unit team have been particularly helpful in agreeing consensus recommendations within the BCMS clinic prescribing guidance. Ongoing evaluation drives service development and includes a BCMS database a... European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2896010 Fri, 16 Oct 2009 12:47:11 +0100 2896010 http://www.medworm.com/index.php?rid=2896009&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003771%2Fabstract%3Frss%3Dyes In this study, we examined the expression of SOCS 1-7 genes in normal and breast cancer tissue and correlated this with several clinico-pathological and prognostic factors. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2896009 Fri, 16 Oct 2009 12:47:11 +0100 2896009 http://www.medworm.com/index.php?rid=2896008&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS074879830900376X%2Fabstract%3Frss%3Dyes Introduction: Nipple discharge (ND) constitutes around 5% of breast clinic presentations with surgical intervention being reserved for pathological or suspicious ND. The aim of this study was to determine the malignant yield from surgery for ND and to assess the association between malignancy and pre-operative findings. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2896008 Fri, 16 Oct 2009 12:47:10 +0100 2896008 http://www.medworm.com/index.php?rid=2896007&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003758%2Fabstract%3Frss%3Dyes Introduction: To evaluate the accuracy of cytological diagnosis of breast cancers greater than 11mm in detecting invasive cancers and therefore the ability to use fine needle aspiration (FNA) as the sole diagnostic parameter. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2896007 Fri, 16 Oct 2009 12:47:10 +0100 2896007 http://www.medworm.com/index.php?rid=2896006&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003746%2Fabstract%3Frss%3Dyes This study aims to examine the relationship between mammaglobin A expression in breast cancer specimens with pathological grades/markers. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2896006 Fri, 16 Oct 2009 12:47:10 +0100 2896006 http://www.medworm.com/index.php?rid=2896005&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003734%2Fabstract%3Frss%3Dyes In our unit, new breast cancer patients are counselled on the probability of nodal metastases using a Kaufman axillary treatment (KAT) scale derived from our own unit's data. This equates to the likelihood of needing a second operation to clear, if opting for initial nodal sampling. We were concerned that following more detailed nodal pathological analysis as part of the new sentinel node procedure, stage migration would alter this probability. We aimed to determine whether our scale needed recalibrating to take account of this. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2896005 Fri, 16 Oct 2009 12:47:10 +0100 2896005 http://www.medworm.com/index.php?rid=2896004&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003722%2Fabstract%3Frss%3Dyes This study compares the efficacy of injection of 2mls of undiluted blue dye with 2mls of blue dye diluted in a further 3mls of saline. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2896004 Fri, 16 Oct 2009 12:47:10 +0100 2896004 http://www.medworm.com/index.php?rid=2896003&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003710%2Fabstract%3Frss%3Dyes Introduction: Seromas constitute a common complication following surgery for breast cancer and closed drainage is used routinely to reduce its incidence. The aim of this study was to evaluate the influence of number of drains on patient discomfort, seroma formation, and hospital stay after mastectomy for breast cancer. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2896003 Fri, 16 Oct 2009 12:47:10 +0100 2896003 http://www.medworm.com/index.php?rid=2896002&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003709%2Fabstract%3Frss%3Dyes Introduction: Lymphoedema following breast cancer treatment is a chronic, disabling condition. Following introduction of sentinel lymph node biopsy (SLNB) for axillary staging only the patients with positive axilla have completion clearance. How much has SLNB reduced the morbidity of lymphoedema in our DGH? (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2896002 Fri, 16 Oct 2009 12:47:10 +0100 2896002 http://www.medworm.com/index.php?rid=2896001&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003692%2Fabstract%3Frss%3Dyes Introduction: The Van Nuys Prognostic Index (VNPI) is a numerical index designed to guide treatment following Breast Conserving Surgery for DCIS. It combines size, margin and grade and separates patients into low risk group suitable for treatment with excision only, moderate risk group suitable for excision with radiotherapy and high-risk group where mastectomy is recommended. The authors tested the validity of VNPI and the proposed benefit of adjuvant radiotherapy. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2896001 Fri, 16 Oct 2009 12:47:10 +0100 2896001 http://www.medworm.com/index.php?rid=2896000&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003680%2Fabstract%3Frss%3Dyes Introduction: The CTCF- paralogous transcriptional factor, BORIS, is a member of the Cancer- Testis gene family specifically expressed in the testis, but abnormally expressed in various malignancies including breast cancer. The aim of the study was to investigate the expression of BORIS in the leukocyte fractions from Breast cancer patients and healthy donors. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2896000 Fri, 16 Oct 2009 12:47:10 +0100 2896000 http://www.medworm.com/index.php?rid=2895999&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003679%2Fabstract%3Frss%3Dyes Introduction: Intra-operative radiotherapy (IORT) with Intrabeam® (Carl Zeiss, Germany) has been used since 2000 in the international randomised TARGIT Trial to determine if there is equivalence between the novel IORT technique and conventional external beam radiotherapy (EBRT) in women with early breast cancer. Some patients were unsuitable for inclusion in our trial for a number of reasons and were given IORT as a single treatment off-trial. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895999 Fri, 16 Oct 2009 12:47:10 +0100 2895999 http://www.medworm.com/index.php?rid=2895998&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003667%2Fabstract%3Frss%3Dyes Aim: The aim of the audit was to look at the accuracy of using blue dye alone for identifying Sentinel nodes and to look at false negative rates. Background: We are currently in the audit phase of the Almanac study. All patients having axillary surgery (who are not in the Almanac study) will have blue dye injected at time of operation. The MDT prior to operation will have decided whether patients are having a sample or full dissection. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895998 Fri, 16 Oct 2009 12:47:10 +0100 2895998 http://www.medworm.com/index.php?rid=2895997&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003655%2Fabstract%3Frss%3Dyes In this study, mRNA expression of CHIP and LOX were assessed in a cohort of breast cancers and correlated to clinico-pathological parameters over a 10 year follow-up period. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895997 Fri, 16 Oct 2009 12:47:10 +0100 2895997 http://www.medworm.com/index.php?rid=2895996&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003643%2Fabstract%3Frss%3Dyes This study investigates whether there is a maximum number of sentinel lymph nodes (SLN) that need to be excised without compromising the false negative (FN) rate of this procedure. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895996 Fri, 16 Oct 2009 12:47:10 +0100 2895996 http://www.medworm.com/index.php?rid=2895995&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003631%2Fabstract%3Frss%3Dyes Introduction: Within the NHSBSP the majority of patients attending for screening are asymptomatic. Significant breast symptoms or signs can be noted at the time of screening and are an indication for recall to an assessment clinic (NHSBSP publication no.49). The aim of this study was to review the outcome of patients recalled to an assessment clinic due to breast symptoms. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895995 Fri, 16 Oct 2009 12:47:10 +0100 2895995 http://www.medworm.com/index.php?rid=2895994&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS074879830900362X%2Fabstract%3Frss%3Dyes Introduction: Phyllodes Tumor accounts for 0.5% to 1.0% of all breast tumors, difficulty in diagnosis arise from similarity to a more common fibroadenomas, potentially to recur locally and/or metastasize, diagnostic and therapeutic procedures remaining a challenge. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895994 Fri, 16 Oct 2009 12:47:09 +0100 2895994 http://www.medworm.com/index.php?rid=2895993&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003618%2Fabstract%3Frss%3Dyes Introduction: Lymph node status (LN) is the most important prognostic indicator in breast cancer. Preoperative assessment of axilla with ultrasound with or without cytology helps us to advise patients' appropriate surgery to the axilla. This is a recommendation in the latest NICE guidelines. A proportion of patients with normal ultrasound of the axillae do still have metastasis in the lymph nodes on histological assessment post excision. We feel the size of the metastasis may have an influence in such assessment. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895993 Fri, 16 Oct 2009 12:47:09 +0100 2895993 http://www.medworm.com/index.php?rid=2895992&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003606%2Fabstract%3Frss%3Dyes This study takes a cohort of female patients with invasive breast cancer who died in 2005-07 and looks backwards in time giving a different perspective on breast cancer survival. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895992 Fri, 16 Oct 2009 12:47:09 +0100 2895992 http://www.medworm.com/index.php?rid=2895991&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS074879830900359X%2Fabstract%3Frss%3Dyes Introduction: Recently it has been published that high cytoplasmic total Src kinase and activated (Y419) Src kinase expression is associated with worse clinical outcome in breast cancer patients. This observation is potentiated in ER negative patients. It's also known that ER/PR positive patients with acquired tamoxifen resistance have a better outcome than ER/PR negative when total Src is highly expressed in the nucleus. Aim of this study was to establish the significance and correlation of PR status to clinical and Src kinase expression data of our cohort. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895991 Fri, 16 Oct 2009 12:47:09 +0100 2895991 http://www.medworm.com/index.php?rid=2895990&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003588%2Fabstract%3Frss%3Dyes Introduction: Pilot results, investigating mRNA expression levels of SKFMs, have shown that Src and Lyn were highest expressed in invasive breast cancer tissue, and that Lck and Lyn were higher expressed in ER negative compared to ER positive tumours. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895990 Fri, 16 Oct 2009 12:47:06 +0100 2895990 http://www.medworm.com/index.php?rid=2895989&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003576%2Fabstract%3Frss%3Dyes Introduction: Pre-operative lymphoscintigram for axillary SLNB requires on-site nuclear medicine facilities which are not available at district general hospitals and may not be required for successful SLNB. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895989 Fri, 16 Oct 2009 12:47:06 +0100 2895989 http://www.medworm.com/index.php?rid=2895988&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003564%2Fabstract%3Frss%3Dyes Introduction: Implant-based breast reconstruction, whether expander or prosthesis, is currently the most common technique for immediate breast reconstruction (IBR) after mastectomy for cancer. Whilst loss of the reconstruction, due to infection or cutaneous necrosis and extrusion, is rare, it is a devastating complication and almost 70% undergo no further reconstructive attempts. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895988 Fri, 16 Oct 2009 12:47:06 +0100 2895988 http://www.medworm.com/index.php?rid=2895987&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003552%2Fabstract%3Frss%3Dyes Introduction: For large tumours and those in less favourable locations, standard breast conserving therapy (BCT) is being replaced by more imaginative oncoplastic breast surgery (OBS) techniques that draw on plastic surgery principles to both anticipate and avoid poor aesthetic outcomes and further reduce the rate of mastectomy. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895987 Fri, 16 Oct 2009 12:47:06 +0100 2895987 http://www.medworm.com/index.php?rid=2895986&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003540%2Fabstract%3Frss%3Dyes Introduction: The Department of Health has introduced Payment by Results whereby Hospital Trusts charge Primary Care Trusts (PCTs) for work undertaken. This relies on accurate completion of spell summaries (TTOs) and coding to determine levels of reimbursement. This audit reviewed the breast surgery undertaken within the Portsmouth Breast Unit to assess whether tariffs charged were in line with actual work undertaken. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895986 Fri, 16 Oct 2009 12:47:06 +0100 2895986 http://www.medworm.com/index.php?rid=2895985&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003539%2Fabstract%3Frss%3Dyes Liver receptor homolog-1 (LRH-1; NR5A2) is an orphan member of the Ftz-F1 family of nuclear receptors, which comprises four members (NR5A1-NR5A4). It is expressed in endodermal derived tissues. LRH-1 has been linked a number of developmental, metabolic and proliferative processes, and plays an important role in cholesterol and lipid homeostasis. Uncontrolled LRH-1 activity participates in the induction of intestinal tumours. LRH-1 protein expression has been detected by immunohistochemistry in tumour cells of human mammary ductal carinomas. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895985 Fri, 16 Oct 2009 12:47:06 +0100 2895985 http://www.medworm.com/index.php?rid=2895984&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003527%2Fabstract%3Frss%3Dyes Introduction: Women over 70 have low self referral rates for breast screening and most are unaware of screening availability. Screening women aged >70 is less effective compared to younger women, but benefit is gained in fitter older women. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895984 Fri, 16 Oct 2009 12:47:06 +0100 2895984 http://www.medworm.com/index.php?rid=2895983&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003515%2Fabstract%3Frss%3Dyes Introduction: To evaluate the effect of introducing the mammotome on the number of indeterminate breast biopsy results (B3 /B4) and the subsequent impact on the number of surgical guide wire biopsies. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895983 Fri, 16 Oct 2009 12:47:06 +0100 2895983 http://www.medworm.com/index.php?rid=2895982&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003503%2Fabstract%3Frss%3Dyes This study investigated the implementation rates of MDT treatment decisions and examined factors associated with changed decisions. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895982 Fri, 16 Oct 2009 12:47:06 +0100 2895982 http://www.medworm.com/index.php?rid=2895981&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003497%2Fabstract%3Frss%3Dyes Background: Patients who develop ipsilateral breast tumour recurrence (IBTR) after breast conserving surgery have traditionally been offered salvage mastectomy. In Guildford breast conserving surgery is offered as an option for these patients if feasible. There is little evidence in the literature on the outcome of these patients. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895981 Fri, 16 Oct 2009 12:47:06 +0100 2895981 http://www.medworm.com/index.php?rid=2895980&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003485%2Fabstract%3Frss%3Dyes This study aimed to assess the accuracy of data recorded about theatre activity and explore the financial implications of inaccurate coding. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895980 Fri, 16 Oct 2009 12:47:05 +0100 2895980 http://www.medworm.com/index.php?rid=2895979&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003473%2Fabstract%3Frss%3Dyes Introduction: Breast cancer treatment aims to achieve cure if possible or to reduce the risk of local and distant recurrence to the minimum. In patients treated for primary breast cancer who develop locoregional recurrence some will have true localised recurrence whereas in other patients it is a sign of synchronous distant metastatic disease. The aim of this study was to attempt to identify factors that predict for true local versus local plus distant recurrence. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895979 Fri, 16 Oct 2009 12:47:05 +0100 2895979 http://www.medworm.com/index.php?rid=2895978&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003461%2Fabstract%3Frss%3Dyes Introduction: There is an increasing detection of indeterminate lesions on breast ultrasound. The aim of this study was to evaluate the pathological features of these lesions and determine their yield of malignant histology. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895978 Fri, 16 Oct 2009 12:47:05 +0100 2895978 http://www.medworm.com/index.php?rid=2895977&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS074879830900345X%2Fabstract%3Frss%3Dyes Introduction: Patients with a positive sentinel node biopsy (SNB) may undergo delayed completion axillary dissection (dALND) which is arguably technically more demanding then axillary dissection without SNB. Where intra-operative analysis is available, immediate completion axillary dissection (iALND) can be performed. It is not known if there is a difference in the total number of lymph nodes or the number of metastatic nodes harvested between the 3 possible approaches. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895977 Fri, 16 Oct 2009 12:47:05 +0100 2895977 http://www.medworm.com/index.php?rid=2895976&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003448%2Fabstract%3Frss%3Dyes Introduction: Oxidative stress has been implicated as a contributory factor in the development of breast cancer. Reactive oxygen species can initiate lipid peroxidation, the reactive secondary products of which can induce oxidative DNA damage and mutations in the p53 tumour suppressor gene. We have correlated the levels of lipid peroxdation products; malondialdehyde and 8-iso-Prostaglandin F2α (8-iso-PGF2α), in patients with primary breast cancer with known prognostic factors such as ER-status, HER2 status and stage and grade of the tumour. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895976 Fri, 16 Oct 2009 12:47:05 +0100 2895976 http://www.medworm.com/index.php?rid=2895975&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003436%2Fabstract%3Frss%3Dyes Background: SLNB in advance of definitive surgery permits completion axillary lymph node (ALND) at the same time as mastectomy and avoids a concomitant axillary procedure in the majority of patients. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895975 Fri, 16 Oct 2009 12:47:05 +0100 2895975 http://www.medworm.com/index.php?rid=2895974&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003424%2Fabstract%3Frss%3Dyes We present our experience of novel strategies to correct these deformities. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895974 Fri, 16 Oct 2009 12:47:05 +0100 2895974 http://www.medworm.com/index.php?rid=2895973&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003412%2Fabstract%3Frss%3Dyes Introduction: Sentinel lymph node biopsy (SLNB) has replaced axillary node clearance (ANC) as the operation of choice for staging breast cancer patients. SLNB allows removal of fewer lymph nodes with a more thorough pathologic evaluation of each node. Accordingly more micrometastases (mmet) and isolated tumour cells (ITCs) are now identified. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895973 Fri, 16 Oct 2009 12:47:05 +0100 2895973 http://www.medworm.com/index.php?rid=2895972&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003400%2Fabstract%3Frss%3Dyes Introduction: Proteomic analysis with mass spectrometry of blood and urine is an attractive resource for the identification of putative biomarkers. The aim is to develop tests which are minimally invasive, reproducible, sensitive and specific and can distinguish between breast cancer, benign breast disease and healthy controls. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895972 Fri, 16 Oct 2009 12:47:05 +0100 2895972 http://www.medworm.com/index.php?rid=2895971&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003394%2Fabstract%3Frss%3Dyes Introduction: MRI breasts in invasive lobular cancer are increasingly used as there can be multifocality/multicentricity and bilaterality. MRI breasts have high sensitivity but low specificity which may result in indeterminate lesions. This can lead to further investigations and delay in the start of treatment particularly if facilities are not available locally for MRI guided biopsies. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895971 Fri, 16 Oct 2009 12:47:05 +0100 2895971 http://www.medworm.com/index.php?rid=2895970&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003382%2Fabstract%3Frss%3Dyes Introduction: Conventional specimen X-ray and Faxitron are important modalities to confirm excision and adequacy of margins of impalpable breast cancer specimens. We hypothesized whether intraoperative Faxitron would be of benefit in palpable cancers in reducing the need for further surgery to clear margins. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895970 Fri, 16 Oct 2009 12:47:05 +0100 2895970 http://www.medworm.com/index.php?rid=2895969&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003370%2Fabstract%3Frss%3Dyes Introduction: Estimation of the size of breast malignancies with imaging is important for pre-operative planning and intraoperative resection. With the increasing use of intraoperative Faxitron X-ray we assessed how accurate this method of imaging was compared with initial mammography and histological size. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895969 Fri, 16 Oct 2009 12:47:05 +0100 2895969 http://www.medworm.com/index.php?rid=2895968&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003357%2Fabstract%3Frss%3Dyes Methods: Preoperative MRI was performed in 20 women with invasive lobular carcinoma. The clinical findings and tumour measurements on mammography, ultrasound and MRI were noted and compared with the histological size following excision. The type of surgery performed, excision margins and further surgery were also recorded. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895968 Fri, 16 Oct 2009 12:47:05 +0100 2895968 http://www.medworm.com/index.php?rid=2895967&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003345%2Fabstract%3Frss%3Dyes Introduction: In our hospital increasing numbers of patients are undergoing day case surgery for intermediate breast procedures such as wide local excision and sentinel node biopsy, with several benefits including reduced cost. Our aim was to assess whether this treatment pathway is acceptable to patients. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895967 Fri, 16 Oct 2009 12:47:05 +0100 2895967 http://www.medworm.com/index.php?rid=2895966&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003333%2Fabstract%3Frss%3Dyes Introduction: Around 5% of breast needle core biopsies (NCB) are reported as B3 - uncertain malignant potential. Cellular atypia appears to be an important determinant. In the absence of National Health Service Breast Screening Programme (NHSBSP) quality assurance targets to report cellular atypia in NCB specimens, this study sought to establish the proportion of histopathological reports for B3 lesions referring to cellular atypia, their subsequent diagnostic management and clinical significance. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895966 Fri, 16 Oct 2009 12:47:05 +0100 2895966 http://www.medworm.com/index.php?rid=2895965&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003321%2Fabstract%3Frss%3Dyes We describe a novel technique of non-bifid fish-tail plasty and its aim to avoid revision surgery. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895965 Fri, 16 Oct 2009 12:47:04 +0100 2895965 http://www.medworm.com/index.php?rid=2895964&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS074879830900331X%2Fabstract%3Frss%3Dyes Introduction: The superiority of ultrasound (US) over clinical examination in the assessment of axillary nodes in patients with breast carcinoma is well recognised. The aim of the study is to evaluate the role of US-guided fine needle aspiration cytology (FNAC) of nodes deemed equivocal or abnormal on US, in choosing the appropriate initial axillary procedure. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895964 Fri, 16 Oct 2009 12:47:04 +0100 2895964 http://www.medworm.com/index.php?rid=2895963&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003308%2Fabstract%3Frss%3Dyes Introduction: The use of SLNB to stage early breast cancer is now routine. The current NICE guidance recommends pre-operative ultrasound (U/S) evaluation of the axilla and ultrasound-guided needle sampling of abnormal lymph nodes. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895963 Fri, 16 Oct 2009 12:47:04 +0100 2895963 http://www.medworm.com/index.php?rid=2895962&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003291%2Fabstract%3Frss%3Dyes Introduction: Health information is one of the most frequently sought topics on the Internet. However, due to its unregulated nature, the information published by medical websites sites is not always guaranteed to be accurate, complete, and up-to-date. Our aim was to evaluate the quality, accessibility and readability of information available on the World-Wide Web for breast cancer patients. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895962 Fri, 16 Oct 2009 12:47:04 +0100 2895962 http://www.medworm.com/index.php?rid=2895961&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS074879830900328X%2Fabstract%3Frss%3Dyes Introduction: The impact of increasing breast specialisation reported by this Breast Unit between 1987-1997 (1) triggered a further review of our subsequent activity. Methods: All elective in-patient and day case procedures between 1998-2008 were identified from booked admission systems. Operations were grouped into 6 categories. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895961 Fri, 16 Oct 2009 12:47:04 +0100 2895961 http://www.medworm.com/index.php?rid=2895960&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003278%2Fabstract%3Frss%3Dyes Introduction: Adjuvant treatment guidelines (1,2,3) recommend that patients with breast cancer who are not low risk & have received Tamoxifen for 2-3 years should switch to Aromatase Inhibitors (AIs) for the completion of their adjuvant treatment. We sought to clarify if adjuvant switches have been made in our patients. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895960 Fri, 16 Oct 2009 12:47:04 +0100 2895960 http://www.medworm.com/index.php?rid=2895959&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003266%2Fabstract%3Frss%3Dyes Introduction: SLNB is one of the surgical options to determine axillary nodal involvement. SLNB avoids the morbidity associated with axillary node clearance. Selection for SLNB currently varies between units and a 25% risk of a second axillary procedure is quoted in our unit. The MSKN has been developed to predict the likelihood of metastatic spread to the Sentinel Lymph Node (SLN) for individual patients. The aim of the study was to determine whether MSKN accurately predicted SLN involvement for our patients. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895959 Fri, 16 Oct 2009 12:47:04 +0100 2895959 http://www.medworm.com/index.php?rid=2895958&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003254%2Fabstract%3Frss%3Dyes Introduction: PCR analysis (GeneSearchTM) is a validated method for intra-operative assessment of sentinel lymph nodes (SLNs), to identify which patients require axillary node clearance (ANC). The aim of this study was to assess the viability of this technique in terms of theatre utilisation. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895958 Fri, 16 Oct 2009 12:47:04 +0100 2895958 http://www.medworm.com/index.php?rid=2895957&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003242%2Fabstract%3Frss%3Dyes Aims: BASO guidelines recommend pre-operative staging investigations in breast cancer surgery to detect metastatic disease. The aim of this study was to assess the efficiency with which these investigations detected metastatic disease pre-operatively and altered patient management. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895957 Fri, 16 Oct 2009 12:47:04 +0100 2895957 http://www.medworm.com/index.php?rid=2895956&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003230%2Fabstract%3Frss%3Dyes Aims: To determine whether infiltrating lobular carcinoma (ILC) is associated with high positive margin rates for single stage lumpectomy procedures. To define clinical or histological characteristics that might influence the positive margin rate,thereby affecting treatment decisions. To identify factors predictive of margin involvement and the need for re-operation. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895956 Fri, 16 Oct 2009 12:47:04 +0100 2895956 http://www.medworm.com/index.php?rid=2895955&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003229%2Fabstract%3Frss%3Dyes This study aims to examine recurrence rates in breast cancer patients who underwent breast conserving surgery, to identify factors associated with recurrence and to compare locoregional recurrence rates to national guidelines issued by the Association of Breast Surgery at BASO, 2005. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895955 Fri, 16 Oct 2009 12:47:04 +0100 2895955 http://www.medworm.com/index.php?rid=2895954&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003217%2Fabstract%3Frss%3Dyes Introduction: Intra-operative assessment (IOA) of sentinel lymph node biopsy (SLNB) with touch imprint cytology (TIC) is a recognized technique to stage the axilla. Axillary clearance is performed during the primary procedure (breast conservation surgery/mastectomy) if IOA is positive. This means that there is some uncertainty pre-operatively in the patient's mind regarding the extent of surgery that will be undertaken. The aim of this study was to see if IOA lead to increase in patient's anxiety about the operation. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895954 Fri, 16 Oct 2009 12:47:04 +0100 2895954 http://www.medworm.com/index.php?rid=2895953&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003205%2Fabstract%3Frss%3Dyes Introduction: The study aimed to investigate whether the size or number of RS/CSL predicts the presence of any associated malignancy or the risk of developing subsequent breast cancer. It also aimed to compare the incidence of breast cancer in patients treated for radial scars with that in age-standardised controls. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895953 Fri, 16 Oct 2009 12:47:04 +0100 2895953 http://www.medworm.com/index.php?rid=2895952&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003199%2Fabstract%3Frss%3Dyes Background: The role for Sentinel Lymph Node Biopsy (SLNB) in patients eligible for breast conservation surgery (BCS) remains controversial. 10-30% of patients with pre-operative diagnosis of DCIS will have an invasive component subsequently detected in the resected specimen. These patients will require a second operation for axillary staging. We sought to identify the characteristics of patients with a pre-operative diagnosis of DCIS eligible for BCS who are most likely to harbour an invasive component, with the aim of identifying those who might benefit from SLNB. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895952 Fri, 16 Oct 2009 12:47:03 +0100 2895952 http://www.medworm.com/index.php?rid=2895951&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003187%2Fabstract%3Frss%3Dyes Introduction: Neoadjuvant chemotherapy (NC) is used in treating locally advanced operable breast cancer. After surgery, further adjuvant treatment is offered based on the estrogen receptor(ER), progesterone receptor(PR) and HER2 status of the core biopsy taken preoperatively. However a change in ER/PR or HER2 status following NC could have profound effect on adjuvant treatment. The aim of our study was to determine the percentage of patients whose ER/PR, HER2 receptor expression change with NC and if these changes lead to change in their adjuvant treatment. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895951 Fri, 16 Oct 2009 12:47:03 +0100 2895951 http://www.medworm.com/index.php?rid=2895950&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003175%2Fabstract%3Frss%3Dyes Introduction: The aim of this study was to investigate the ability of blue dye assisted node sampling to predict axillary staging, as compared to standard axillary node sampling (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895950 Fri, 16 Oct 2009 12:47:03 +0100 2895950 http://www.medworm.com/index.php?rid=2895949&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003163%2Fabstract%3Frss%3Dyes Objective: Women with breast cancer or at high risk have special needs not addressed by breast cancer or menopause clinics. Specialist opinion differs over safety of hormonal agents and there are a variety of non-hormonal agents available for symptomatic relief. The aim of this project was to identify patient need, produce customised assessment and develop treatment strategies. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895949 Fri, 16 Oct 2009 12:47:03 +0100 2895949 http://www.medworm.com/index.php?rid=2895948&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003151%2Fabstract%3Frss%3Dyes Introduction: Theatre times are slightly increased with intra-operative sentinel node analysis (ioaSNB), however node positive patients avoid a second hospital admission and a second operation. It is uncertain if overall this leads to changes in theatre and hospital bed utilisation. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895948 Fri, 16 Oct 2009 12:47:03 +0100 2895948 http://www.medworm.com/index.php?rid=2895947&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS074879830900314X%2Fabstract%3Frss%3Dyes Introduction: Breast cancer surgery continues to evolve, aiming to conserve breast tissue and minimise axillary dissection. There is a general impression however that mastectomy avoids the need for subsequent radiotherapy particularly in elderly patients. Adjuvant radiotherapy following mastectomy (ARFM) may still be required for close resection margins or nodal disease. We reviewed ARFM for patients in our symptomatic breast unit. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895947 Fri, 16 Oct 2009 12:47:03 +0100 2895947 http://www.medworm.com/index.php?rid=2895946&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003138%2Fabstract%3Frss%3Dyes Introduction: Preoperative radiological axillary staging identifies lymph node positive patients at risk of systemic disease. Positron emission tomography/computed tomography (PETCT) appears to be an accurate imaging modality for breast cancer patients. The purpose of this study was to evaluate the impact of PETCT on patients with a preoperative diagnosis of axillary metastasis. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895946 Fri, 16 Oct 2009 12:47:03 +0100 2895946 http://www.medworm.com/index.php?rid=2895945&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003126%2Fabstract%3Frss%3Dyes Introduction: About 60-70% of patients with early breast cancer undergo breast-conserving surgery. Of these, approximately 25-30% are found to have close or involved margins at final histology and require further surgery to ensure clear margins. Current methods of intra-operative margin assessment are unreliable. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895945 Fri, 16 Oct 2009 12:47:03 +0100 2895945 http://www.medworm.com/index.php?rid=2895944&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003114%2Fabstract%3Frss%3Dyes Aims: The management of many diseases, including breast cancer, is often influenced by the pre-operative stage or dimension of the tumour. Breast cancer patients treated with primary endocrine therapy are reviewed regularly to assess tumour response, but often by different clinicians. Accurate assessment of lesion size is therefore essential. The aim of this study was to assess the accuracy of clinical sizing of lesions and investigate the impact of two measuring adjuncts on size estimation. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895944 Fri, 16 Oct 2009 12:47:03 +0100 2895944 http://www.medworm.com/index.php?rid=2895943&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003102%2Fabstract%3Frss%3Dyes Introduction: Gynaecomastia is a benign condition of the male breast resulting from an imbalance in oestrogen/androgen ratio. Most of the circulating oestrogen is produced by the aromatisation of testosterone thus aromatase inhibitors (AIs) could be the mainstay of treatment. The aim of this study was to identify patients treated with the AI Arimidex, assess its effectiveness and identify any factors that may predict response to treatment. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895943 Fri, 16 Oct 2009 12:47:03 +0100 2895943 http://www.medworm.com/index.php?rid=2895942&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003096%2Fabstract%3Frss%3Dyes We present our experience in a District General Hospital. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895942 Fri, 16 Oct 2009 12:47:03 +0100 2895942 http://www.medworm.com/index.php?rid=2895941&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003084%2Fabstract%3Frss%3Dyes Background: Invasive lobular carcinoma (ILC) accounts for 5 - 15% of invasive breast malignancies Recent evidence has suggested that the incidence of ILC and invasive ductal-lobular carcinoma (IDLC) in the US has increased in comparison to invasive ductal carcinoma (IDC).The aim of this study was to see whether this change has also been reflected in our region. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895941 Fri, 16 Oct 2009 12:47:03 +0100 2895941 http://www.medworm.com/index.php?rid=2895940&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003072%2Fabstract%3Frss%3Dyes Introduction: It is recognised that the presence of a systemic inflammatory response is prognostic in a number of metastatic and operable tumours. Thus far, results in operable breast cancer have been conflicting. We assessed the relationship between long term outcome and the systemic inflammatory response in primary operable breast cancer. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895940 Fri, 16 Oct 2009 12:47:01 +0100 2895940 http://www.medworm.com/index.php?rid=2895939&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003060%2Fabstract%3Frss%3Dyes Background: Post operative analgesia is often underestimated in breast surgery resulting in long term sequelae. Opiates and epidural analgesia may produce complications and limits early rehabilitation. We compare the analgesic effects of intercostal nerve block with subcutaneous infiltration in breast surgery. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895939 Fri, 16 Oct 2009 12:47:01 +0100 2895939 http://www.medworm.com/index.php?rid=2895938&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003059%2Fabstract%3Frss%3Dyes Introduction: Epidemiological studies suggest that moderate intensity recreational physical activity (PA) improves breast cancer survival. We aimed to assess the current levels of PA in breast cancer survivors and a cohort of women with benign disease attending clinics in Glasgow. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895938 Fri, 16 Oct 2009 12:47:01 +0100 2895938 http://www.medworm.com/index.php?rid=2895937&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003047%2Fabstract%3Frss%3Dyes This study aimed to analyse a series of invasive ductal carcinomas to characterise P-cadherin and functional analyses of P-cadherin using breast cancer cell lines. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895937 Fri, 16 Oct 2009 12:47:01 +0100 2895937 http://www.medworm.com/index.php?rid=2895936&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003035%2Fabstract%3Frss%3Dyes Introduction: With the introduction of SLNB, breast cancer patients with nodal disease had to undergo second surgery. The aim of our study was to correlate the accuracy of ultrasound in redefining surgery in these patients. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895936 Fri, 16 Oct 2009 12:47:01 +0100 2895936 http://www.medworm.com/index.php?rid=2895935&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003023%2Fabstract%3Frss%3Dyes Introduction: Microscopically clear margins are necessary to minimize the likelihood of breast relapse in breast conserving surgery (BCS).Several factors have been identified to associate with margin involvement after BCS. It is assumed that reexcision to achieve clear margins is as effective as complete tumour removal at a single procedure, however, the efficacy of reexcision in this context has not been well studied. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895935 Fri, 16 Oct 2009 12:47:01 +0100 2895935 http://www.medworm.com/index.php?rid=2895934&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309003011%2Fabstract%3Frss%3Dyes Introduction: In December 2009 a government target will demand all new breast referrals are seen within 2 weeks. Currently fast-track patients are seen within two weeks and non-urgent five weeks. We aimed to assess the breast clinic referral pattern according to pathology in fast-track, non-urgent and tertiary groups. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895934 Fri, 16 Oct 2009 12:47:01 +0100 2895934 http://www.medworm.com/index.php?rid=2895933&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS074879830900300X%2Fabstract%3Frss%3Dyes Introduction: Ductal Carcinoma in situ (DCIS) is a non invasive carcinoma. It is a malignant precursor of invasive breast cancer. DCIS is usually not detected as a palpable lesion. It is increasingly identified in mammographic screening. The aim of surgery is to achieve complete excision of the in-situ tumour and to minimise local recurrence. National and regional guidelines emphasise the importance of clear resection margins. They also state that intraoperative specimen radiography should be carried out for all cases of DCIS treated by breast conservation surgery. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895933 Fri, 16 Oct 2009 12:47:01 +0100 2895933 http://www.medworm.com/index.php?rid=2895932&cid=s_35554_6_f&fid=35554&url=http%3A%2F%2Fwww.cancer-surgery.net%2Farticle%2FPIIS0748798309002996%2Fabstract%3Frss%3Dyes Introduction: An audit was carried out to determine the accuracy of intra-operative touch imprint cytology (TIC) in the diagnosis of sentinel lymph node (SLN) macrometastases (>2mm) and micrometastases (>0.2-2mm) in patients with breast cancer. (Source: European Journal of Surgical Oncology) European Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=2895932 Fri, 16 Oct 2009 12:47:01 +0100 2895932