Heart via MedWorm.com MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Heart' source. Sun, 21 Mar 2010 14:01:16 +0100 JournalScan http://www.medworm.com/index.php?rid=3375522&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F6%2F487%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3375522 Thu, 18 Mar 2010 12:24:40 +0100 3375522 Acute myocardial infarction due to paradoxical embolism: successful catheter aspiration and histological correlation http://www.medworm.com/index.php?rid=3375521&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F6%2F485%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3375521 Thu, 18 Mar 2010 12:24:40 +0100 3375521 Post-myocardial infarction biventricular pseudoaneurysm with bidirectional shunt http://www.medworm.com/index.php?rid=3375520&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F6%2F483%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3375520 Thu, 18 Mar 2010 12:24:40 +0100 3375520 Prevention of cardiovascular disease in asymptomatic people http://www.medworm.com/index.php?rid=3375519&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F6%2F477%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3375519 Thu, 18 Mar 2010 12:24:40 +0100 3375519 Inherited cardiovascular conditions: the challenges of genomic medicine http://www.medworm.com/index.php?rid=3375518&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F6%2F474%3Frss%3D1 The report Heart to Heart published in 2009 by the Foundation for Genomics and Population Health provided an account of new health services needs arising from greater scientific and clinical understanding of inherited cardiovascular conditions. Informed by advice from an expert working group, the report makes recommendations for the development of specialised inherited cardiovascular conditions services within the UK. The report will also be of relevance internationally, wherever cardiologists and geneticists aim to provide care for these patients and their families. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3375518 Thu, 18 Mar 2010 12:24:40 +0100 3375518 Response to Peter Joseph http://www.medworm.com/index.php?rid=3375517&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F6%2F473%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3375517 Thu, 18 Mar 2010 12:24:40 +0100 3375517 Response to Peter Joseph http://www.medworm.com/index.php?rid=3375516&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F6%2F472-b%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3375516 Thu, 18 Mar 2010 12:24:40 +0100 3375516 Response to Bhaskaran et al's "Effects of air pollution on the incidence of myocardial infarction" http://www.medworm.com/index.php?rid=3375515&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F6%2F472-a%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3375515 Thu, 18 Mar 2010 12:24:40 +0100 3375515 Correction http://www.medworm.com/index.php?rid=3375514&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F6%2F471-a%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3375514 Thu, 18 Mar 2010 12:24:40 +0100 3375514 Ethnicity-related differences in left ventricular function, structure and geometry: a population study of UK Indian Asian and European white subjects http://www.medworm.com/index.php?rid=3375513&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F6%2F466%3Frss%3D1 Conclusion Compared to European white people, Indian Asians had attenuated longitudinal LV function, higher LV filling pressure and demonstrated a greater degree of concentric remodelling independent of other demographic and clinical parameters. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3375513 Thu, 18 Mar 2010 12:24:40 +0100 3375513 Mean platelet volume predicts early death in acute pulmonary embolism http://www.medworm.com/index.php?rid=3375512&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F6%2F460%3Frss%3D1 Conclusion MPV is an independent predictor of early death in APE. Moreover, MPV in APE is associated with right ventricular dysfunction and myocardial injury. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3375512 Thu, 18 Mar 2010 12:24:39 +0100 3375512 Septic palmar emboli in a case of staphylococcal aortic endocarditis http://www.medworm.com/index.php?rid=3375511&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F6%2F459%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3375511 Thu, 18 Mar 2010 12:24:39 +0100 3375511 Gender perspective on risk factors, coronary lesions and long-term outcome in young patients with ST-elevation myocardial infarction http://www.medworm.com/index.php?rid=3375510&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F6%2F453%3Frss%3D1 Conclusions STEMI below age 46 is a more rare condition in women than in men and more often related to cardiovascular risk factors. More than 90% of both men and women had coronary lesions, in women more often single vessel lesions. Female sex is associated with higher in-hospital mortality, while long-term mortality is low without difference between genders. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3375510 Thu, 18 Mar 2010 12:24:39 +0100 3375510 Lipid re-screening: what is the best measure and interval? http://www.medworm.com/index.php?rid=3375509&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F6%2F448%3Frss%3D1 Conclusion The signal-to-noise ratios of standard single lipid measures (TC, LDL and HDL) are weak over 3 years and decisions based on these measures are potentially misleading. The ratios, TC/HDL and LDL/HDL, seem to be better measures for monitoring assessments. The lipid re-screening interval should be >3 years for those not taking cholesterol-lowering drugs. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3375509 Thu, 18 Mar 2010 12:24:39 +0100 3375509 Speckle myocardial imaging modalities for early detection of myocardial impairment in isolated left ventricular non-compaction http://www.medworm.com/index.php?rid=3375508&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F6%2F440%3Frss%3D1 Conclusions LV SMI values are reduced in patients with iLVNC, even those with normal EF and PWTDI. The most accurate SMI modalities to discriminate between patients and controls are longitudinal sS mean of the six apical segments, LV apical rotation or LV torsion rate. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3375508 Thu, 18 Mar 2010 12:24:39 +0100 3375508 Diversity of molecular forms of plasma brain natriuretic peptide in heart failure--different proBNP-108 to BNP-32 ratios in atrial and ventricular overload http://www.medworm.com/index.php?rid=3375507&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F6%2F432%3Frss%3D1 Conclusion These results suggest that BNP-32 and proBNP-108 is increased in HF and that the proBNP/total BNP ratio increases in association with pathophysiological conditions such as ventricular overload. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3375507 Thu, 18 Mar 2010 12:24:39 +0100 3375507 Combined non-invasive anatomical and functional assessment with MSCT and MRI for the detection of significant coronary artery disease in patients with an intermediate pre-test likelihood http://www.medworm.com/index.php?rid=3375506&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F6%2F425%3Frss%3D1 Conclusion The anatomical and functional data obtained with MSCT and MRI are complementary for the assessment of coronary artery disease. These findings support the sequential or combined assessment of anatomy and function. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3375506 Thu, 18 Mar 2010 12:24:39 +0100 3375506 Molecular forms of natriuretic peptides in heart failure and their implications http://www.medworm.com/index.php?rid=3375505&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F6%2F419%3Frss%3D1 Atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) are important biomarkers in the diagnosis and risk stratification for heart failure (HF). These peptides are synthesised as inactive precursors, pro-ANP and pro-BNP, which are converted to biologically active 28 amino acid ANP and 32 amino acid BNP, respectively. Most immunoassays currently used in the clinical setting, however, do not determine precise molecular forms of these natriuretic peptides, which may vary depending on the pathophysiological state of HF. Analysis from chromatography-based studies reveals that in HF inactive pro-ANP and pro-BNP forms often predominate. This indicates that the bioactive forms of natriuretic peptides may not be processed proportionally in patients with advanced HF. Distinguishing the... Heart journals http://www.medworm.com/rss/comments.php?id=3375505 Thu, 18 Mar 2010 12:24:39 +0100 3375505 Current status of percutaneous coronary intervention in China http://www.medworm.com/index.php?rid=3375504&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F6%2F415%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3375504 Thu, 18 Mar 2010 12:24:39 +0100 3375504 Which lipid fraction is the target and how often should this be monitored? http://www.medworm.com/index.php?rid=3375503&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F6%2F413%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3375503 Thu, 18 Mar 2010 12:24:39 +0100 3375503 Non-invasive anatomy and physiology: the new 'gold standard'? http://www.medworm.com/index.php?rid=3375502&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F6%2F411%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3375502 Thu, 18 Mar 2010 12:24:39 +0100 3375502 JournalScan http://www.medworm.com/index.php?rid=3328405&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F5%2F409%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3328405 Tue, 02 Mar 2010 14:19:59 +0100 3328405 JournalScan for March 2010_1 http://www.medworm.com/index.php?rid=3323836&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F5%2F409%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3323836 Tue, 02 Mar 2010 14:19:59 +0100 3323836 Diagnosing an MI: don't trust the monitor! http://www.medworm.com/index.php?rid=3323835&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F5%2F408%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3323835 Tue, 02 Mar 2010 14:19:59 +0100 3323835 Interventional rescue strategy after malpositioning of a percutaneous aortic valve http://www.medworm.com/index.php?rid=3323834&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F5%2F407%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3323834 Tue, 02 Mar 2010 14:19:59 +0100 3323834 Tako-tsubo cardiomyopathy: findings on cardiac CT and coronary catheterisation http://www.medworm.com/index.php?rid=3323833&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F5%2F406%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3323833 Tue, 02 Mar 2010 14:19:59 +0100 3323833 Arrhythmias and sport practice http://www.medworm.com/index.php?rid=3323832&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F5%2F398%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3323832 Tue, 02 Mar 2010 14:19:59 +0100 3323832 Three dimensional echocardiography: approaches and clinical utility http://www.medworm.com/index.php?rid=3323831&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F5%2F390%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3323831 Tue, 02 Mar 2010 14:19:59 +0100 3323831 Author's response http://www.medworm.com/index.php?rid=3323830&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F5%2F389-b%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3323830 Tue, 02 Mar 2010 14:19:59 +0100 3323830 P: the neglected deflection http://www.medworm.com/index.php?rid=3323829&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F5%2F389-a%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3323829 Tue, 02 Mar 2010 14:19:59 +0100 3323829 The DSC score http://www.medworm.com/index.php?rid=3323828&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F5%2F388-b%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3323828 Tue, 02 Mar 2010 14:19:59 +0100 3323828 Development and validation of a clinical index to predict survival after cardiac resynchronisation therapy http://www.medworm.com/index.php?rid=3323827&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F5%2F388-a%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3323827 Tue, 02 Mar 2010 14:19:59 +0100 3323827 Intracardiac bone cement embolism http://www.medworm.com/index.php?rid=3323826&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F5%2F387%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3323826 Tue, 02 Mar 2010 14:19:59 +0100 3323826 Percutaneous mitral valve leaflet repair for mitral regurgitation: NICE guidance http://www.medworm.com/index.php?rid=3323825&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F5%2F385%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3323825 Tue, 02 Mar 2010 14:19:59 +0100 3323825 Walking speed and subclinical atherosclerosis in healthy older adults: the Whitehall II study http://www.medworm.com/index.php?rid=3323824&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F5%2F380%3Frss%3D1 Conclusions Short-distance walking speed is associated with metabolic risk and subclinical atherosclerosis in older adults without overt CVD. These data suggest that a non-aerobically challenging walking test reflects the presence of underlying vascular disease. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3323824 Tue, 02 Mar 2010 14:19:58 +0100 3323824 Diagnostic value of perfusion cardiovascular magnetic resonance in patients with angina pectoris but normal coronary angiograms assessed by intracoronary acetylcholine testing http://www.medworm.com/index.php?rid=3323823&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F5%2F372%3Frss%3D1 Conclusions Reversible perfusion defects depicted by perfusion-CMR in patients without significant CAD are mostly due to coronary epicardial or microvascular dysfunction, and correct interpretation of such perfusion-CMR results may enable targeted treatment. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3323823 Tue, 02 Mar 2010 14:19:58 +0100 3323823 The antiplatelet effect of aspirin is reduced by proton pump inhibitors in patients with coronary artery disease http://www.medworm.com/index.php?rid=3323822&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F5%2F368%3Frss%3D1 Conclusions Patients with CAD treated with PPIs had a reduced platelet response to aspirin, as shown by increased residual platelet aggregation and platelet activation, compared with patients with CAD not taking PPIs. Concomitant use of aspirin and PPIs might reduce the cardiovascular protection by aspirin. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3323822 Tue, 02 Mar 2010 14:19:58 +0100 3323822 Determinants of functional recovery after myocardial infarction of patients treated with bone marrow-derived stem cells after thrombolytic therapy http://www.medworm.com/index.php?rid=3323821&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F5%2F362%3Frss%3D1 Conclusions The global LVEF recovers most significantly after intracoronary infusion of BMC in patients with the most severe impairment of LVEF on admission. The baseline levels of natriuretic peptides seem also to be associated with LVEF recovery after BMC treatment. Trial registration ClinicalTrials.gov number, NCT00363324. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3323821 Tue, 02 Mar 2010 14:19:58 +0100 3323821 Adiponectin acts as a positive indicator of left ventricular diastolic dysfunction in patients with hypertrophic cardiomyopathy http://www.medworm.com/index.php?rid=3323820&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F5%2F357%3Frss%3D1 Conclusions These data document that adiponectin is an indicator of LV diastolic dysfunction in patients with HCM. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3323820 Tue, 02 Mar 2010 14:19:58 +0100 3323820 Late benefits of dual-chamber pacing in obstructive hypertrophic cardiomyopathy: a 10-year follow-up study http://www.medworm.com/index.php?rid=3323819&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F5%2F352%3Frss%3D1 Conclusions Pacing in HCM results in a significant reduction in obstruction, improvement of symptoms and exercise capacity that is progressive and may be achieved after a long period of time. In this series, only 18% of cases needed a more aggressive treatment to relieve residual obstruction and obtain a satisfactory symptomatic status. In conclusion, these results emphasise the need for new controlled studies of pacing with a longer follow-up. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3323819 Tue, 02 Mar 2010 14:19:57 +0100 3323819 Carotid sinus syndrome, should we pace? A multicentre, randomised control trial (Safepace 2) http://www.medworm.com/index.php?rid=3323818&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F5%2F347%3Frss%3D1 Conclusions These results question the use of pacing in CICSH. However, the study was underpowered and also patient characteristics differed from those in Safepace 1—participants were physically and cognitively frailer. Further work is necessary to assess cardiac pacing in this setting. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3323818 Tue, 02 Mar 2010 14:19:57 +0100 3323818 Early C-reactive protein in the prediction of long-term outcomes after acute coronary syndromes: a meta-analysis of longitudinal studies http://www.medworm.com/index.php?rid=3323817&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F5%2F339%3Frss%3D1 Conclusions Greater early blood CRP moderately increases long-term risk of recurrent cardiovascular events or death, and may be a valuable prognostic predictor in patients after ACS. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3323817 Tue, 02 Mar 2010 14:19:57 +0100 3323817 Cardioversion of atrial fibrillation: the use of antiarrhythmic drugs http://www.medworm.com/index.php?rid=3323816&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F5%2F333%3Frss%3D1 Atrial fibrillation (AF) is the commonest atrial arrhythmia and represents a large burden on modern health services. Large multicentre randomised trials have demonstrated that a rhythm control strategy (using antiarrhythmic drugs and direct current (DC) cardioversion) has no morbidity or mortality advantage over rate control. Therefore, for most patients, attempts to cardiovert AF to sinus rhythm (SR) should be reserved for those patients who are symptomatic despite adequate rate control. For recent-onset AF (<24 h) the use of agents like flecainide can be highly successful to pharmacologically cardiovert AF, although caution should be exercised in patients who have the potential for structural or coronary artery disease because of the risk of proarrhythmia. If there any is doubt a... Heart journals http://www.medworm.com/rss/comments.php?id=3323816 Tue, 02 Mar 2010 14:19:57 +0100 3323816 What can adiponectin say about left ventricular function? http://www.medworm.com/index.php?rid=3323815&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F5%2F331%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3323815 Tue, 02 Mar 2010 14:19:57 +0100 3323815 Long-term benefits of pacing in obstructive hypertrophic cardiomyopathy http://www.medworm.com/index.php?rid=3323814&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F5%2F328%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3323814 Tue, 02 Mar 2010 14:19:57 +0100 3323814 C-reactive protein for risk assessment in coronary artery disease http://www.medworm.com/index.php?rid=3323813&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F5%2F325%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3323813 Tue, 02 Mar 2010 14:19:57 +0100 3323813 JournalScan http://www.medworm.com/index.php?rid=3316904&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2F323%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316904 Mon, 01 Mar 2010 10:21:18 +0100 3316904 027 Protective role of peroxisome proliferator-activated receptor I/I' in cardiac dysfunction and organ injury/inflammation caused by endotoxin in mice http://www.medworm.com/index.php?rid=3316883&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2Fe8-b%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316883 Mon, 01 Mar 2010 10:21:18 +0100 3316883 026 Plasma levels of the novel vasodilatory gas hydrogen sulphide are associated with adiposity http://www.medworm.com/index.php?rid=3316882&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2Fe8-a%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316882 Mon, 01 Mar 2010 10:21:18 +0100 3316882 025 Is Depressed myocyte contractility an early event in the natural history of heart failure? http://www.medworm.com/index.php?rid=3316881&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2Fe7-d%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316881 Mon, 01 Mar 2010 10:21:18 +0100 3316881 024 Endothelial Nox4 NADPH oxidase enhances vasodilatation via hydrogen peroxide-induced hyperpolarisation and reduces blood pressure http://www.medworm.com/index.php?rid=3316880&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2Fe7-c%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316880 Mon, 01 Mar 2010 10:21:18 +0100 3316880 023 Transcriptional regulation of p40PHOX and p47PHOX expression via HBP1 in endothelial cells http://www.medworm.com/index.php?rid=3316879&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2Fe7-b%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316879 Mon, 01 Mar 2010 10:21:18 +0100 3316879 022 Hypoxic preconditioning of cardiosphere-derived cells to increase retention in the infarcted heart http://www.medworm.com/index.php?rid=3316878&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2Fe7-a%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316878 Mon, 01 Mar 2010 10:21:18 +0100 3316878 021 Phenotype of the ACTC E99K transgenic mouse reproduces hypertrophic cardiomyopathy in patients http://www.medworm.com/index.php?rid=3316877&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2Fe6-d%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316877 Mon, 01 Mar 2010 10:21:18 +0100 3316877 020 Determination of troponin I phosphorylation sites in human heart muscle http://www.medworm.com/index.php?rid=3316876&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2Fe6-c%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316876 Mon, 01 Mar 2010 10:21:18 +0100 3316876 019 The time course of inorganic phosphate release and actomyosin ATPase rate in permeabilised cardiac trabeculae http://www.medworm.com/index.php?rid=3316875&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2Fe6-b%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316875 Mon, 01 Mar 2010 10:21:18 +0100 3316875 018 Guanidinoacetate N-methyltransferase knockout mice exhibit normal left ventricular remodelling, haemodynamics and survival after myocardial infarction despite lack of phosphocreatine http://www.medworm.com/index.php?rid=3316874&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2Fe6-a%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316874 Mon, 01 Mar 2010 10:21:18 +0100 3316874 017 Concentration-dependent protection by no donors against ischaemia-reperfusion injury in perfused rat hearts http://www.medworm.com/index.php?rid=3316873&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2Fe5-c%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316873 Mon, 01 Mar 2010 10:21:18 +0100 3316873 016 Evidence for inward rectifier potassium channels in HL-1 cells http://www.medworm.com/index.php?rid=3316872&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2Fe5-b%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316872 Mon, 01 Mar 2010 10:21:18 +0100 3316872 015 Investigating metabolic flux in the hyperthyroid heart using hyperpolarised magnetic resonance http://www.medworm.com/index.php?rid=3316871&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2Fe5-a%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316871 Mon, 01 Mar 2010 10:21:18 +0100 3316871 014 Thin filaments reconstituted with troponin extracted from patients with hypertrophic obstructive cardiomyopathy are functionally abnormal http://www.medworm.com/index.php?rid=3316870&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2Fe4-d%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316870 Mon, 01 Mar 2010 10:21:18 +0100 3316870 013 Regulation of gene transcription by hydrogen peroxide in cardiomyocytes http://www.medworm.com/index.php?rid=3316869&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2Fe4-c%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316869 Mon, 01 Mar 2010 10:21:18 +0100 3316869 012 Is nitric oxide synthase present in mitochondria? http://www.medworm.com/index.php?rid=3316868&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2Fe4-b%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316868 Mon, 01 Mar 2010 10:21:18 +0100 3316868 011 A new molecular mechanism for familial dilated cardiomyopathy based on studies with intact mutant transgenic mouse and human explanted heart muscle http://www.medworm.com/index.php?rid=3316867&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2Fe4-a%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316867 Mon, 01 Mar 2010 10:21:18 +0100 3316867 010 Cardiomyocyte-specific overexpression of Nox4 attenuates adverse cardiac remodelling after myocardial infarction http://www.medworm.com/index.php?rid=3316866&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2Fe3-c%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316866 Mon, 01 Mar 2010 10:21:18 +0100 3316866 009 Endothelial-specific overexpression of Nox2 enhances angiotensin II-induced cardiac dysfunction and fibrosis http://www.medworm.com/index.php?rid=3316865&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2Fe3-b%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316865 Mon, 01 Mar 2010 10:21:18 +0100 3316865 008 Neuronal nitric oxide synthase-mediated regulation of myocardial redox state and {beta}3 adrenergic receptor responses http://www.medworm.com/index.php?rid=3316864&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2Fe3-a%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316864 Mon, 01 Mar 2010 10:21:18 +0100 3316864 007 Roles of P47phox S303/S304 phosphorylation in TNF{alpha}-induced endothelial reactive oxygen species production and mitogen-activated protein kinase activation http://www.medworm.com/index.php?rid=3316863&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2Fe2-c%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316863 Mon, 01 Mar 2010 10:21:18 +0100 3316863 006 Normobaric hypoxia impairs cardiac energetics in normal human volunteers http://www.medworm.com/index.php?rid=3316862&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2Fe2-b%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316862 Mon, 01 Mar 2010 10:21:18 +0100 3316862 005 Nox2-deficient bone marrow-derived macrophages exhibit defects in cell spreading and migration http://www.medworm.com/index.php?rid=3316861&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2Fe2-a%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316861 Mon, 01 Mar 2010 10:21:18 +0100 3316861 004 Peroxisome proliferator-activated receptor alpha is essential for cardiac adaptation to chronic hypoxia http://www.medworm.com/index.php?rid=3316860&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2Fe1-d%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316860 Mon, 01 Mar 2010 10:21:18 +0100 3316860 003 Real-time assessment of Krebs cycle metabolism with hyperpolarised [2-13c]pyruvate http://www.medworm.com/index.php?rid=3316859&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2Fe1-c%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316859 Mon, 01 Mar 2010 10:21:18 +0100 3316859 002 Compensation for impaired myocardial phosphotransfer in guanidinoacetate-N-methyltransferase knockout mice http://www.medworm.com/index.php?rid=3316858&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2Fe1-b%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316858 Mon, 01 Mar 2010 10:21:18 +0100 3316858 001 Substrate utilisation by the failing human heart by direct quantification using arteriovenous blood sampling http://www.medworm.com/index.php?rid=3316857&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2Fe1-a%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316857 Mon, 01 Mar 2010 10:21:18 +0100 3316857 Sinus rhythm with isolated pulmonary vein fibrillation http://www.medworm.com/index.php?rid=3316903&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2F322%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316903 Mon, 01 Mar 2010 10:21:17 +0100 3316903 Dynamic volume 320-slice CT in the assessment of patent ductus arteriosus for percutaneous closure http://www.medworm.com/index.php?rid=3316902&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2F321%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316902 Mon, 01 Mar 2010 10:21:17 +0100 3316902 Biomarkers in heart failure http://www.medworm.com/index.php?rid=3316901&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2F314%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316901 Mon, 01 Mar 2010 10:21:17 +0100 3316901 NICE evaluation of transmyocardial laser revascularisation and percutaneous laser revascularisation for refractory angina http://www.medworm.com/index.php?rid=3316900&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2F312%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316900 Mon, 01 Mar 2010 10:21:17 +0100 3316900 The authors' reply http://www.medworm.com/index.php?rid=3316899&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2F310-c%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316899 Mon, 01 Mar 2010 10:21:17 +0100 3316899 T2-weighted magnetic resonance imaging to assess myocardial oedema http://www.medworm.com/index.php?rid=3316898&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2F310-b%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316898 Mon, 01 Mar 2010 10:21:17 +0100 3316898 Measuring waist circumference: do not "throw the baby out with the bath water"! http://www.medworm.com/index.php?rid=3316897&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2F310-a%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316897 Mon, 01 Mar 2010 10:21:17 +0100 3316897 Response from Dr Paul Poirier to P De Groot's: Cardiologists and abdominal obesity: lost in translation? http://www.medworm.com/index.php?rid=3316896&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2F309-b%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316896 Mon, 01 Mar 2010 10:21:17 +0100 3316896 Waist circumference: a waste of time? http://www.medworm.com/index.php?rid=3316895&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2F309-a%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316895 Mon, 01 Mar 2010 10:21:17 +0100 3316895 Functional outcomes after the Ross (pulmonary autograft) procedure assessed with magnetic resonance imaging and cardiopulmonary exercise testing http://www.medworm.com/index.php?rid=3316894&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2F304%3Frss%3D1 Conclusion This study demonstrates minor autograft and homograft dysfunction in the majority of patients after the Ross procedure, associated with good ventricular function and exercise capacity. In addition, minor scar was present in a third of patients with no functional consequences. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316894 Mon, 01 Mar 2010 10:21:17 +0100 3316894 Childhood adversities as predictors of incident coronary heart disease and cerebrovascular disease http://www.medworm.com/index.php?rid=3316893&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2F298%3Frss%3D1 Conclusions In this prospective population-based sample, childhood adversities were associated with a significantly increased risk of objectively verified cardiovascular disease, especially among women but to a lesser extent among men. More studies with prospective settings are needed to confirm the association and possible mechanisms. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316893 Mon, 01 Mar 2010 10:21:17 +0100 3316893 Elevated left atrial pressure estimated by Doppler echocardiography is a key determinant of mitral valve tenting in functional mitral regurgitation http://www.medworm.com/index.php?rid=3316892&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2F289%3Frss%3D1 Conclusions In both patients with preserved and reduced LVEF, mitral tenting that leads to FMR is mainly determined by both mitral tethering forces—that is, displacement of papillary muscles and by pushing forces—that is, increased left atrial pressure. This study underscores that LV preload is a key determinant of FMR. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316892 Mon, 01 Mar 2010 10:21:17 +0100 3316892 Deformation imaging describes right ventricular function better than longitudinal displacement of the tricuspid ring http://www.medworm.com/index.php?rid=3316891&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2F281%3Frss%3D1 Conclusions RV function of CTEPH patients improves steadily after PEA. Unlike S, SR and RVFAC, this is not reflected by TAPSE because of postoperative changes in overall heart motion. Motion independent deformation parameters (S, SR) appear superior in the accurate description of regional RV function (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316891 Mon, 01 Mar 2010 10:21:17 +0100 3316891 Digoxin in atrial fibrillation: report from the Stockholm Cohort study of Atrial Fibrillation (SCAF) http://www.medworm.com/index.php?rid=3316890&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2F275%3Frss%3D1 Conclusion Digoxin is mainly given to an elderly and frailer subset of patients with AF and is thus associated with an increased mortality. When differences in patient characteristics are accounted for digoxin use seems to have a neutral effect on mortality and major cardiovascular events in patients with AF. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316890 Mon, 01 Mar 2010 10:21:17 +0100 3316890 Cumulative patient effective dose and acute radiation-induced chromosomal DNA damage in children with congenital heart disease http://www.medworm.com/index.php?rid=3316889&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2F269%3Frss%3D1 Conclusion Children with congenital heart disease are exposed to a significant cumulative dose. Indirect cancer risk estimations and direct DNA data both emphasise the need for strict radiation dose optimisation in children. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316889 Mon, 01 Mar 2010 10:21:17 +0100 3316889 Brief low-workload myocardial ischaemia induces protection against exercise-related increase of platelet reactivity in patients with coronary artery disease http://www.medworm.com/index.php?rid=3316888&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2F263%3Frss%3D1 Conclusions A short episode of myocardial ischaemia induces protection against an exercise-induced increase of platelet reactivity. These data also suggest a role for adenosine in this phenomenon. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316888 Mon, 01 Mar 2010 10:21:17 +0100 3316888 Prevention of cardiovascular disease: why do we neglect the most potent intervention? http://www.medworm.com/index.php?rid=3316887&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2F261%3Frss%3D1 Despite a large volume of evidence supporting its cardioprotective properties and its other numerous established health benefits, physical activity is not a serious prescription option for the primary prevention of cardiovascular disease. On the other hand, health services increasingly focus on pharmacological prevention without considering properly the long-term consequences of medication. Ethical and feasibility considerations suggest that evidence on the protective value of physical activity may need to be evaluated using criteria different from those applying to pharmacological trials. The collateral health benefits of physical activity prescription support its use as standard option in preventive health care. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316887 Mon, 01 Mar 2010 10:21:17 +0100 3316887 Cardiorenal syndrome in decompensated heart failure http://www.medworm.com/index.php?rid=3316886&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2F255%3Frss%3D1 Worsening renal function during treatment of acute decompensated heart failure (ADHF) often complicates the treatment course of heart failure. Furthermore, the development of worsening renal function is a strong independent predictor of long-term adverse outcomes. Sometimes referred to as ‘cardiorenal syndrome,’ the definition varies widely, and the overall understanding of pathogenesis is limited. This is probably owing to the lack of precision and characterisation of renal compromise during treatment of heart failure. Traditionally, the predominant cause has been attributed to impairment of cardiac output and relative underfilling of arterial perfusion. Emerging data have led to a resurgence of interest in the importance of venous congestion and elevated intra-abdominal press... Heart journals http://www.medworm.com/rss/comments.php?id=3316886 Mon, 01 Mar 2010 10:21:17 +0100 3316886 Assessing outcomes after paediatric cardiac surgery: which test is best? http://www.medworm.com/index.php?rid=3316885&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2F253%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316885 Mon, 01 Mar 2010 10:21:17 +0100 3316885 The danger of radiation exposure in the young http://www.medworm.com/index.php?rid=3316884&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F4%2F251%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3316884 Mon, 01 Mar 2010 10:21:17 +0100 3316884 JournalScan http://www.medworm.com/index.php?rid=3240965&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F3%2F249%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3240965 Thu, 04 Feb 2010 15:44:54 +0100 3240965 Not just alternating ectopics http://www.medworm.com/index.php?rid=3240964&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F3%2F247%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3240964 Thu, 04 Feb 2010 15:44:54 +0100 3240964 Appearance of a double aortic arch in DiGeorge syndrome on ECG-gated 64 detector row computed tomography http://www.medworm.com/index.php?rid=3240963&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F3%2F245%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3240963 Thu, 04 Feb 2010 15:44:54 +0100 3240963 Membranous interventricular septal aneurysm resulted in complete atrioventricular block http://www.medworm.com/index.php?rid=3240962&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F3%2F244%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3240962 Thu, 04 Feb 2010 15:44:54 +0100 3240962 Cardiovascular magnetic resonance imaging in patients with acute myocardial infarction http://www.medworm.com/index.php?rid=3240961&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F3%2F237%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3240961 Thu, 04 Feb 2010 15:44:54 +0100 3240961 Hypoplastic left heart syndrome http://www.medworm.com/index.php?rid=3240960&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F3%2F231%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3240960 Thu, 04 Feb 2010 15:44:54 +0100 3240960 The NICE guidelines for percutaneous epicardial catheter ablation of ventricular tachycardia: symptomatic of a guideline-obsessed health service? http://www.medworm.com/index.php?rid=3240959&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F3%2F229%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3240959 Thu, 04 Feb 2010 15:44:53 +0100 3240959 Authors' response http://www.medworm.com/index.php?rid=3240958&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F3%2F228%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3240958 Thu, 04 Feb 2010 15:44:53 +0100 3240958 The additive value of biomarkers to clinical risk scores in acute coronary syndrome. Are biomarkers really ready for real world usage? http://www.medworm.com/index.php?rid=3240957&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F3%2F227%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3240957 Thu, 04 Feb 2010 15:44:53 +0100 3240957 Authors' response http://www.medworm.com/index.php?rid=3240956&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F3%2F226-d%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3240956 Thu, 04 Feb 2010 15:44:53 +0100 3240956 Aetiology of sudden cardiac death in athletes in the UK http://www.medworm.com/index.php?rid=3240955&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F3%2F226-c%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3240955 Thu, 04 Feb 2010 15:44:53 +0100 3240955 Authors' response http://www.medworm.com/index.php?rid=3240954&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F3%2F226-b%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3240954 Thu, 04 Feb 2010 15:44:53 +0100 3240954 A case of sudden cardiac arrest: is it truly idiopathic? http://www.medworm.com/index.php?rid=3240953&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F3%2F226-a%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3240953 Thu, 04 Feb 2010 15:44:53 +0100 3240953 Real-time perfusion echocardiography during treadmill exercise and dobutamine stress testing http://www.medworm.com/index.php?rid=3240952&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F3%2F220%3Frss%3D1 Conclusion Myocardial perfusion imaging with RTP improves the detection of CAD during both DSE and TESE. During TESE, the subendocardial perfusion defects improve WM sensitivity by delineating subendocardial WM abnormalities. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3240952 Thu, 04 Feb 2010 15:44:53 +0100 3240952 Single-beat estimation of the left ventricular end-diastolic pressure-volume relationship in patients with heart failure http://www.medworm.com/index.php?rid=3240951&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F3%2F213%3Frss%3D1 Conclusions Single-beat EDPVRs obtained from hearts spanning a wide range of sizes and conditions accurately predicted directly measured EDPVRs with low RMSE. Single-beat EDPVR indices correlated well with directly measured values, but systematic biases were present at low and high pressures. The single-beat method facilitates less invasive EDPVR estimation, particularly when coupled with emerging non-invasive techniques to measure pressures and volumes. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3240951 Thu, 04 Feb 2010 15:44:53 +0100 3240951 Comparison of mass and targeted screening strategies for cardiovascular risk: simulation of the effectiveness, cost-effectiveness and coverage using a cross-sectional survey of 3921 people http://www.medworm.com/index.php?rid=3240950&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F3%2F208%3Frss%3D1 Conclusions Targeted screening strategies are less costly than mass screening, and can identify up to 84% of high-risk individuals. The additional resources required for mass screening may not be justified. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3240950 Thu, 04 Feb 2010 15:44:53 +0100 3240950 Coronary collateral growth by external counterpulsation: a randomised controlled trial http://www.medworm.com/index.php?rid=3240949&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F3%2F202%3Frss%3D1 Conclusions ECP appears to be effective in promoting coronary collateral growth. The extent of collateral function improvement is related to the amount of improvement in the systemic endothelial function. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3240949 Thu, 04 Feb 2010 15:44:53 +0100 3240949 Relationship between plasma inflammatory markers and plaque fibrous cap thickness determined by intravascular optical coherence tomography http://www.medworm.com/index.php?rid=3240948&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F3%2F196%3Frss%3D1 Conclusion There is an inverse linear correlation between fibrous cap thickness and plasma levels of inflammatory markers. The plasma hs-CRP concentration is the strongest independent predictor of TCFA. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3240948 Thu, 04 Feb 2010 15:44:53 +0100 3240948 Infarct size and left ventricular function in the PRoximal Embolic Protection in Acute myocardial infarction and Resolution of ST-segment Elevation (PREPARE) trial: ancillary cardiovascular magnetic resonance study http://www.medworm.com/index.php?rid=3240947&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F3%2F190%3Frss%3D1 Conclusions Primary PCI with combined proximal embolic protection and thrombus aspiration in STEMI patients did not result in significant differences in final infarct size or left ventricular function at follow-up CMR. In addition, there was no difference in the incidence of major adverse cardiac and cerebral events at 6 months. Trial registration number ISRCTN71104460. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3240947 Thu, 04 Feb 2010 15:44:53 +0100 3240947 Calcium-channel blockers decrease clopidogrel-mediated platelet inhibition http://www.medworm.com/index.php?rid=3240946&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F3%2F186%3Frss%3D1 Conclusion CCBs decrease clopidogrel-mediated platelet inhibition in patients undergoing angioplasty and stenting for cardiovascular disease. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3240946 Thu, 04 Feb 2010 15:44:53 +0100 3240946 Focal atrial tachycardia http://www.medworm.com/index.php?rid=3240945&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F3%2F181%3Frss%3D1 is a relatively uncommon arrhythmia. Nevertheless, the management of highly symptomatic patients with focal atrial tachycardia can be problematic owing to the poor response to medical treatment. Moreover, focal atrial tachycardia can trigger other atrial arrhythmias like atrial fibrillation and flutter. Radiofrequency ablation of focal atrial tachycardia is extremely successful and this approach is becoming the preferred treatment for symptomatic patients.In this review, we describe the pathophysiology, anatomical localisation, clinical features, diagnosis and therapeutic options for the management of focal atrial tachycardia. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3240945 Thu, 04 Feb 2010 15:44:53 +0100 3240945 Clopidogrel and calcium-channel blockers: a clinically important interaction? http://www.medworm.com/index.php?rid=3240944&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F3%2F179%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3240944 Thu, 04 Feb 2010 15:44:53 +0100 3240944 Strategies to screen and reduce vascular risk--putting statins in the tap water is not the answer http://www.medworm.com/index.php?rid=3240943&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F3%2F177%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3240943 Thu, 04 Feb 2010 15:44:52 +0100 3240943 Depression and cardiac risk: present status and future directions http://www.medworm.com/index.php?rid=3240942&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F3%2F173%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3240942 Thu, 04 Feb 2010 15:44:52 +0100 3240942 JournalScan http://www.medworm.com/index.php?rid=3154350&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F2%2F171%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3154350 Sat, 09 Jan 2010 00:13:07 +0100 3154350 Anomalous origin of the left anterior descending artery from the pulmonary artery http://www.medworm.com/index.php?rid=3154349&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F2%2F170%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3154349 Sat, 09 Jan 2010 00:13:07 +0100 3154349 Network models for large cities: the European experience http://www.medworm.com/index.php?rid=3154348&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F2%2F164%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3154348 Sat, 09 Jan 2010 00:13:07 +0100 3154348 Three-dimensional echocardiography http://www.medworm.com/index.php?rid=3154347&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F2%2F153%3Frss%3D1 Over the past two to three decades echocardiography has come a considerable distance from the early M-mode machines, and has become an indispensable diagnostic tool in any cardiovascular department. It has long been proved to be safe and cost-effective, and its clinical versatility has steadily increased with the continued integration of newer techniques, such as two-dimensional and harmonic imaging, Doppler and much more. One of the more recent developments in the field is three-dimensional echocardiography (3DE). 3DE, in various forms, has been used as a research tool for many years now, but lately improvements in software and transducer technology have begun to facilitate its integration into clinical practice. As with any technique, 3DE has its strengths and weaknesses, and these must ... Heart journals http://www.medworm.com/rss/comments.php?id=3154347 Sat, 09 Jan 2010 00:13:07 +0100 3154347 Left ventricular hypertrophy: reduction of blood pressure already in the normal range further regresses left ventricular mass http://www.medworm.com/index.php?rid=3154346&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F2%2F148%3Frss%3D1 Conclusions: Reduction in office systolic blood pressure, already in the normal range, of approximately 9 mm Hg, leads to a reduction in left ventricular mass. Further work is required to see if this also leads to a reduction in cardiovascular events. Trial registration number: ISRCTN48331653. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3154346 Sat, 09 Jan 2010 00:13:07 +0100 3154346 Assessment of vascular function: flow-mediated constriction complements the information of flow-mediated dilatation http://www.medworm.com/index.php?rid=3154345&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F2%2F141%3Frss%3D1 Conclusion: In the first protocol, FMD and L-FMC were shown to be reciprocally regulated. A blunted FMD may, in certain cases, be an expression of increased resting vascular activation and not only of impaired endothelial function. In the second protocol, a statistical approach showed that implementation of L-FMC provides a better characterisation than FMD of vascular function in cardiovascular disease. Vascular (endothelial) function is a complex phenomenon which requires a multifaceted approach; it is suggested that a combination of L-FMC and FMD will provide additive and complementary information to "traditional" FMD measurements. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3154345 Sat, 09 Jan 2010 00:13:07 +0100 3154345 Anthropometric assessment of abdominal obesity and coronary heart disease risk in men: the PRIME study http://www.medworm.com/index.php?rid=3154344&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F2%2F136%3Frss%3D1 Conclusion: In middle-aged European men, waist-to-height ratio identifies coronary risk more strongly than waist circumference, waist-to-hip ratio or BMI, though the difference is marginal. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3154344 Sat, 09 Jan 2010 00:13:07 +0100 3154344 Association between anthropometric obesity measures and coronary artery disease: a cross-sectional survey of 16 657 subjects from 444 Polish cities http://www.medworm.com/index.php?rid=3154343&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F2%2F131%3Frss%3D1 Conclusion: This cross-sectional study showed that waist/height2 may potentially offer a slightly higher predictive value of CAD than BMI or waist circumference and revealed an apparent sexual dimorphism in correlations between obesity measures and CAD. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3154343 Sat, 09 Jan 2010 00:13:07 +0100 3154343 Alcohol intake and the risk of coronary heart disease in the Spanish EPIC cohort study http://www.medworm.com/index.php?rid=3154342&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F2%2F124%3Frss%3D1 Conclusions: Alcohol intake in men aged 29–69 years was associated with a more than 30% lower CHD incidence. This study is based on a large prospective cohort study and is free of the abstainer error. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3154342 Sat, 09 Jan 2010 00:13:07 +0100 3154342 Predicting outcome after valve replacement http://www.medworm.com/index.php?rid=3154341&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F2%2F118%3Frss%3D1 Conclusions: One year after valve replacement patients can expect a significant improvement in their exercise tolerance and QOL but their physical QOL is unlikely to be normal. Outcome may be improved by treating depression and modifying negative illness beliefs preoperatively. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3154341 Sat, 09 Jan 2010 00:13:07 +0100 3154341 Preoperative 6-minute walk test adds prognostic information to Euroscore in patients undergoing aortic valve replacement http://www.medworm.com/index.php?rid=3154340&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F2%2F113%3Frss%3D1 Conclusions: The 6MWT is safe and feasible to carry out in patients with severe aortic stenosis before AVR, and provides potentially important functional and prognostic information to clinical assessment and the Euroscore risk score. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3154340 Sat, 09 Jan 2010 00:13:07 +0100 3154340 Myocardial deformation in aortic valve stenosis: relation to left ventricular geometry http://www.medworm.com/index.php?rid=3154339&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F2%2F106%3Frss%3D1 Conclusions In patients with AS, lower average longitudinal strain is related to higher LV mass, concentric geometry and more severe AS. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3154339 Sat, 09 Jan 2010 00:13:07 +0100 3154339 Is there evidence for prognostic benefit following PCI in stable patients? COURAGE and its implications: an interventionalist's view http://www.medworm.com/index.php?rid=3154338&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F2%2F103%3Frss%3D1 The COURAGE study has stimulated intensive discussion about the optimal approach to treatment of patients with stable angina. To some, the study implied that PCI has no clinical benefit versus optimal medical therapy but this is open to alternative considered interpretation. To the interventionalist who deploys optimal medical therapy responsibly, the study highlights the importance of the concept of an ischaemia driven approach. The availability of the pressure wire has provided cardiologists with an important additional tool with which to tailor the delivery of revascularisation to not just the ischaemic patient but also to the ischaemic lesion. Such a strategy applied to COURAGE (and perhaps also to SYNTAX) might provide a very different comparative outcome. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3154338 Sat, 09 Jan 2010 00:13:07 +0100 3154338 An unusual finding at cardiac catheterisation http://www.medworm.com/index.php?rid=3154337&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F2%2F102%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3154337 Sat, 09 Jan 2010 00:13:07 +0100 3154337 Metformin: safety in cardiac patients http://www.medworm.com/index.php?rid=3154336&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F2%2F99%3Frss%3D1 Metformin is a biguanide, insulin sensitiser that reduces blood sugar levels. There are concerns about the risk of lactic acidosis in patients receiving metformin who have procedures requiring iodinated contrast, and in those with renal impairment or heart failure. The data on which these concerns are based are reviewed, with the conclusion that metformin treatment is rarely to blame for lactic acidosis. A generic policy of stopping metformin 48 h before and 48 h after the procedure in all patients is counterintuitive, lacks any evidence base and does not conform to the principles of best practice. In patients with heart failure, although the underlying condition can predispose to lactic acidosis, existing evidence suggests that metformin use is associated with improved outcome rather than... Heart journals http://www.medworm.com/rss/comments.php?id=3154336 Sat, 09 Jan 2010 00:13:07 +0100 3154336 Six-minute walk test: independent prognostic marker? http://www.medworm.com/index.php?rid=3154335&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F2%2F97%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3154335 Sat, 09 Jan 2010 00:13:07 +0100 3154335 Longitudinal myocardial shortening in aortic stenosis: ready for prime time after 30 years of research? http://www.medworm.com/index.php?rid=3154334&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F2%2F95%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3154334 Sat, 09 Jan 2010 00:13:07 +0100 3154334 JournalScan http://www.medworm.com/index.php?rid=3097782&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F1%2F93%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3097782 Thu, 17 Dec 2009 18:08:32 +0100 3097782 Renal disease and acute coronary syndrome http://www.medworm.com/index.php?rid=3097781&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F1%2F86%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3097781 Thu, 17 Dec 2009 18:08:32 +0100 3097781 Echocardiographic follow-up after heart valve replacement http://www.medworm.com/index.php?rid=3097780&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F1%2F75%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3097780 Thu, 17 Dec 2009 18:08:32 +0100 3097780 The authors' reply: http://www.medworm.com/index.php?rid=3097779&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F1%2F73-c%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3097779 Thu, 17 Dec 2009 18:08:32 +0100 3097779 Triple antithrombotic management after stent implantation: when and how? http://www.medworm.com/index.php?rid=3097778&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F1%2F73-b%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3097778 Thu, 17 Dec 2009 18:08:32 +0100 3097778 The authors' reply: http://www.medworm.com/index.php?rid=3097777&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F1%2F73-a%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3097777 Thu, 17 Dec 2009 18:08:32 +0100 3097777 Management of heart failure with preserved ejection fraction: back to the drawing board? http://www.medworm.com/index.php?rid=3097776&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F1%2F72-c%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3097776 Thu, 17 Dec 2009 18:08:32 +0100 3097776 The author's reply: http://www.medworm.com/index.php?rid=3097775&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F1%2F72-b%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3097775 Thu, 17 Dec 2009 18:08:32 +0100 3097775 The impact of prehospital thrombolytic treatment on re-infarction rates http://www.medworm.com/index.php?rid=3097774&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F1%2F72-a%3Frss%3D1 (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3097774 Thu, 17 Dec 2009 18:08:32 +0100 3097774 Left ventricular assist devices http://www.medworm.com/index.php?rid=3097773&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F1%2F63%3Frss%3D1 Left ventricular assist device (LVAD) insertion in patients with advanced heart failure with deteriorating clinical status is life saving, and LVADs are now being inserted into an increasing number of patients with advanced heart failure. They were initially inserted as a bridge to transplantation, and the decreased availability of donor hearts means that an increasing number of patients are requiring LVAD support for survival when their clinical status deteriorates. There is strong evidence that with LVAD unloading, particularly when combined with pharmacological treatment, the patients’ myocardial function can also recover, allowing device removal and avoiding the need for transplantation, immunosuppression and its associated complications. This indication, known as "bridge to reco... Heart journals http://www.medworm.com/rss/comments.php?id=3097773 Thu, 17 Dec 2009 18:08:31 +0100 3097773 Preoperative NT-proBNP and CRP predict perioperative major cardiovascular events in non-cardiac surgery http://www.medworm.com/index.php?rid=3097772&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F1%2F56%3Frss%3D1 Conclusions: High preoperative NT-proBNP or CRP is a strong and independent predictor of perioperative major cardiovascular event in non-cardiac surgery. The predictive power of current clinical risk evaluation system would be strengthened by these biomarkers. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3097772 Thu, 17 Dec 2009 18:08:31 +0100 3097772 Left ventricular twist mechanics in patients with apical hypertrophic cardiomyopathy: assessment with 2D speckle tracking echocardiography http://www.medworm.com/index.php?rid=3097771&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F1%2F49%3Frss%3D1 Conclusion: LV twist in ApHCM was significantly decreased due to a reduction in apical rotation, suggesting that regional myocardial changes in ApHCM can modify the global LV twist mechanics. Given the close interconnection between LV systolic and diastolic function, impairment of LV twist may lead to the loss of early diastolic suction and finally generate diastolic dysfunction in ApHCM. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3097771 Thu, 17 Dec 2009 18:08:31 +0100 3097771 Physical activity and physiological cardiac remodelling in a community setting: the Multi-Ethnic Study of Atherosclerosis (MESA) http://www.medworm.com/index.php?rid=3097770&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F1%2F42%3Frss%3D1 Conclusions: In a community-based population free of clinically apparent cardiovascular disease, higher physical activity levels were associated with proportionally greater left ventricular mass and end-diastolic volume and lower resting heart rate. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3097770 Thu, 17 Dec 2009 18:08:31 +0100 3097770 Continuous, non-invasive measurement of the haemodynamic response to submaximal exercise in patients with diabetes mellitus: evidence of impaired cardiac reserve and peripheral vascular response http://www.medworm.com/index.php?rid=3097769&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F1%2F36%3Frss%3D1 Conclusion: Cardiac response to exercise is attenuated significantly in diabetic individuals. Simultaneously, there is impairment in the regional distribution. These changes could be the harbinger of reduced exercise capacity in diabetics. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3097769 Thu, 17 Dec 2009 18:08:31 +0100 3097769 Type D personality and depressive symptoms are independent predictors of impaired health status following acute myocardial infarction http://www.medworm.com/index.php?rid=3097768&cid=s_29166_7_f&fid=29166&url=http%3A%2F%2Fheart.bmj.com%2Fcgi%2Fcontent%2Fshort%2F96%2F1%2F30%3Frss%3D1 Conclusions: The type D construct is an independent predictor of impaired disease-specific health status. Type D personality, in addition to depression, may thus be an important psychological factor that deserves attention during the period of rehabilitation in post-MI patients. (Source: Heart) Heart journals http://www.medworm.com/rss/comments.php?id=3097768 Thu, 17 Dec 2009 18:08:31 +0100 3097768