MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Histopathology' source. Thu, 09 Feb 2012 00:42:12 +0100 http://www.medworm.com/index.php?rid=5661191&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04122.x Conclusion:  Our results suggest that DLBCL of cFCL type can be identified in extranodal non‐cutaneous sites and shows clinical characteristics similar to genuine cFCL. We propose to expand the concept of cFCL to encompass large cell lymphomas in extranodal sites. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5661191 Wed, 01 Feb 2012 05:00:00 +0100 5661191 http://www.medworm.com/index.php?rid=5651015&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04135.x Conclusions:  Combined study of IGH and IGK rearrangement according to BIOMED‐2 protocols improves clonality detection rate (up to 25% of cases) in HL, even when working on non‐microdissected FFPE tissue. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5651015 Wed, 01 Feb 2012 05:00:00 +0100 5651015 http://www.medworm.com/index.php?rid=5651013&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04137.x Conclusions:  FoxM1, p27kip1 and p21waf1/cip1 showed distinct immunoreactivity according to histological subtype, which may be of value as an ancillary test in the differential diagnosis of pulmonary NE tumours. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5651013 Wed, 01 Feb 2012 05:00:00 +0100 5651013 http://www.medworm.com/index.php?rid=5651012&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04138.x Conclusions:  In summary, Dll4 and Jag1 are expressed in glioblastoma vasculature. These data may define subsets of glioblastoma that might be sensitive (Dll4+/Jag1+) or resistant (Dll4+/Jag1–) to bevacizumab. Our data also suggest that anti‐Dll4 therapy should be evaluated experimentally in glioblastoma. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5651012 Wed, 01 Feb 2012 05:00:00 +0100 5651012 http://www.medworm.com/index.php?rid=5651011&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04142.x Conclusions:  We anticipate that publicly available web applications, such as ImmunoMembrane, will accelerate the adoption of automated image analysis in clinical diagnostics of HER2 IHC. ImmunoMembrane is freely accessible at: http://jvsmicroscope.uta.fi/immunomembrane/. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5651011 Wed, 01 Feb 2012 05:00:00 +0100 5651011 http://www.medworm.com/index.php?rid=5651010&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04148.x Conclusions:  This suggests that, despite their similar morphological appearances, the GCT‐like component of gynandroblastoma has a different molecular basis from conventional adult‐type GCT. This finding underscores a more general principle that morphological similarity does not necessarily indicate molecular identity. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5651010 Wed, 01 Feb 2012 05:00:00 +0100 5651010 http://www.medworm.com/index.php?rid=5651009&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04151.x Conclusion:  The VHLD‐associated cases appeared to be benign, but the sporadic case exhibited a low malignant potential. CCPCs show histological and immunophenotypical similarities with the recently reported clear cell papillary RCC, although the previously unreported apical CD10 and nuclear PAX2 expression may be related to their mesonephric origin. CCPC has a distinctive sub‐epithelial vascular pattern that is consistent with its pathogenesis. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5651009 Wed, 01 Feb 2012 05:00:00 +0100 5651009 http://www.medworm.com/index.php?rid=5651008&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04159.x Conclusions:  Our data demonstrate that bacteria‐related active inflammation results in a sharp increase of DMBT1 levels in enterocytes. These findings substantiate the view that DMBT1 is of functional relevance for host defence and modulation of the course of intestinal bacteria‐related inflammatory responses. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5651008 Wed, 01 Feb 2012 05:00:00 +0100 5651008 http://www.medworm.com/index.php?rid=5630916&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04177.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5630916 Fri, 27 Jan 2012 05:24:39 +0100 5630916 http://www.medworm.com/index.php?rid=5630915&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04108.x Conclusions:  Our study suggests that low WT1 expression and high MC may be indicative of an unfavourable prognosis in patients with advanced malignant peritoneal mesothelioma. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5630915 Fri, 27 Jan 2012 05:24:21 +0100 5630915 http://www.medworm.com/index.php?rid=5630914&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04106.x Conclusions:  Genes involved in resistance to hypoxia are expressed in PVRs, and may play a role in the development of post‐radiation recurrences. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5630914 Fri, 27 Jan 2012 05:24:19 +0100 5630914 http://www.medworm.com/index.php?rid=5630913&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04098.x Conclusions:  CD56 expression in B cell lymphoma is a rare occurrence. FC is able to identify aberrant immunophenotypes that can be useful in the identification and monitoring of B cell lymphoma subtypes. The presence of CD56 reported by the literature on certain DLBCL with extranodal presentation might be related to mechanisms involved in growth and expansion. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5630913 Fri, 27 Jan 2012 05:24:17 +0100 5630913 http://www.medworm.com/index.php?rid=5630912&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04112.x Conclusions:  Our data point to c‐Met expression as one of the factors that distinguishes normal from malignant plasma cells, and indicate that the HGF/c‐Met system is activated in multiple myeloma patients. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5630912 Fri, 27 Jan 2012 05:24:15 +0100 5630912 http://www.medworm.com/index.php?rid=5630911&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04111.x Conclusions:  Patients affected by thymomas showed a significantly higher risk of developing additional malignancies than those in the control groups, and cases that exhibited a predominantly cortical component were more likely to develop other neoplasms. This may be related to the functions of cortical thymic epithelial cells in providing for T lymphocyte maturation through interaction with major histocompatibility complexes. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5630911 Fri, 27 Jan 2012 05:24:13 +0100 5630911 http://www.medworm.com/index.php?rid=5630910&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04126.x Conclusions:  By the use of three markers, this algorithm allowed identification of subgroups of right‐sided CC patients with extremely high and extremely low risk of distant metastases. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5630910 Fri, 27 Jan 2012 05:24:10 +0100 5630910 http://www.medworm.com/index.php?rid=5630909&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04123.x Conclusions:  Taken together, the uniform up‐regulation of desmosomal genes/proteins in the oesophageal mucosa of patients with GERD supports the concept of architectural and molecular changes in the desmosomal compartment in the pathogenesis of GERD. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5630909 Fri, 27 Jan 2012 05:24:08 +0100 5630909 http://www.medworm.com/index.php?rid=5630908&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04121.x Conclusions:  Our results suggest that HMGA1 and HMGA2 are implicated in pancreatic carcinogenesis and may play a role in tumour progression towards a more malignant phenotype. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5630908 Fri, 27 Jan 2012 05:24:06 +0100 5630908 http://www.medworm.com/index.php?rid=5630907&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04119.x Conclusions:  SRs, and particularly TBSRs, are advantageous as compared with DRs regarding the content of ED and the clarity of the data layout. The use of TBSRs leads to a reduction in failed data transfer and therefore to an increase in the quality of pathology reports. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5630907 Fri, 27 Jan 2012 05:23:16 +0100 5630907 http://www.medworm.com/index.php?rid=5611927&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04124.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5611927 Thu, 19 Jan 2012 05:00:00 +0100 5611927 http://www.medworm.com/index.php?rid=5611926&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04093.x Conclusions:  Lack of INI‐1 expression, noted exclusively in RMCs, segregates RMCs into a separate cluster. PAX8 is rarely positive (17%) in UC, is commonly expressed in CDC, RMC, PRCC and CRCC and is superior to PAX2. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5611926 Thu, 19 Jan 2012 05:00:00 +0100 5611926 http://www.medworm.com/index.php?rid=5611925&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04125.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5611925 Thu, 19 Jan 2012 05:00:00 +0100 5611925 http://www.medworm.com/index.php?rid=5611924&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04095.x Conclusions:  The nuclear expression of ERβ indicates that oestrogen may be active in ACC and possibly able to mediate E2‐targeted gene transcription. This study strongly suggests that ERβ may be involved in tumour progression, playing a role in tumour development, and thus corroborating the indication for ER antagonists in the clinical control of ACC. This study opens a new perspective on the potential use of anti‐oestrogens and aromatase inhibitors as therapeutic agents against ACC. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5611924 Thu, 19 Jan 2012 05:00:00 +0100 5611924 http://www.medworm.com/index.php?rid=5611922&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04109.x Conclusions:  This study provides further evidence for the stem cell character of ALDH1+ cells, here in benign breast tissue of cancer and non‐cancer patients throughout non‐lactating adult life, and contributes evidence of benign stromal ALDH1+ cells. The distribution of ductular ALDH1+ stem cells appears to be influenced by hormonal status. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5611922 Thu, 19 Jan 2012 05:00:00 +0100 5611922 http://www.medworm.com/index.php?rid=5611921&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03957.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5611921 Thu, 19 Jan 2012 05:00:00 +0100 5611921 http://www.medworm.com/index.php?rid=5611920&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04021.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5611920 Thu, 19 Jan 2012 05:00:00 +0100 5611920 http://www.medworm.com/index.php?rid=5611919&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04107.x Conclusions:  The main result of the present study is the association of aneuploidy and securin expression. According to our results, securin immunohistochemistry is also a potential new prognosticator for treatment decisions concerning breast cancer patients. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5611919 Thu, 19 Jan 2012 05:00:00 +0100 5611919 http://www.medworm.com/index.php?rid=5599862&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04099.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5599862 Tue, 17 Jan 2012 05:00:00 +0100 5599862 http://www.medworm.com/index.php?rid=5599861&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04097.x Conclusions:  Pattern 1 represents an indolent phase/grade of AITL, unassociated with the development of secondary B‐lineage lymphoma and uninfluenced by treatment regimen. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5599861 Tue, 17 Jan 2012 05:00:00 +0100 5599861 http://www.medworm.com/index.php?rid=5599860&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04104.x Conclusions:  To our knowledge, the SE‐technique is the first to multi‐label antigens, identifying vessel and pericyte architecture in bone marrow by light microscopy. This technique may unravel novel aspects of the composition of the microvessel structures in patients with PMF and related neoplasms. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5599860 Tue, 17 Jan 2012 05:00:00 +0100 5599860 http://www.medworm.com/index.php?rid=5585646&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04100.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5585646 Wed, 11 Jan 2012 05:00:00 +0100 5585646 http://www.medworm.com/index.php?rid=5585645&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04103.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5585645 Wed, 11 Jan 2012 05:00:00 +0100 5585645 http://www.medworm.com/index.php?rid=5611918&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04116.x Conclusion:  The study supports the heterogeneous nature of CRPC and confirms a significant association between PTEN, ERG, AR and SPINK1. Characterizing combined markers will aid in defining PCA subgroups relevant to prognosis contributing to the design of improved therapeutic approaches for CRPC. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5611918 Sun, 01 Jan 2012 05:00:00 +0100 5611918 http://www.medworm.com/index.php?rid=5599859&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04105.x Conclusions:  Immunoreactivity for HMGA2 is diffusely positive in whole tissue sections in most uterine serous carcinomas and negative in most endometrioid carcinomas, although, as with other markers, there is overlap in individual cases. In conjunction with other markers, HMGA2 may be of value in problematic uterine carcinomas where the differential diagnosis includes serous and endometrioid carcinoma. As HMGA2 is expressed in serous EIC, this suggests that it may be implicated in the early development of uterine serous carcinoma. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5599859 Sun, 01 Jan 2012 05:00:00 +0100 5599859 http://www.medworm.com/index.php?rid=5585644&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04102.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5585644 Sun, 01 Jan 2012 05:00:00 +0100 5585644 http://www.medworm.com/index.php?rid=5546057&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04063.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5546057 Wed, 28 Dec 2011 21:24:00 +0100 5546057 http://www.medworm.com/index.php?rid=5539734&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04133.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5539734 Sun, 25 Dec 2011 17:27:18 +0100 5539734 http://www.medworm.com/index.php?rid=5539733&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04072.x Conclusions:  In the majority of cases, clinical presentation and breast imaging are highly suspicious for carcinoma. Definitive pre‐operative pathological diagnosis by core needle biopsy is difficult. CTNNB1 mutation and nuclear β‐catenin expression are frequently detected in sporadic breast fibromatoses, suggesting their potential as a useful tool to distinguish breast fibromatoses from other neoplasms. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5539733 Sun, 25 Dec 2011 17:27:06 +0100 5539733 http://www.medworm.com/index.php?rid=5539732&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04087.x Conclusions:  The presence of gene copy number changes in Spitz naevi as detected by FISH is higher than expected, and Spitz naevi at the genetic level represent a heterogeneous group. The findings of similar cytogenetic alterations in Spitz naevi and melanomas suggest that there should be cautious interpretation of FISH analysis in this setting. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5539732 Sun, 25 Dec 2011 17:27:05 +0100 5539732 http://www.medworm.com/index.php?rid=5539731&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04081.x Conclusions:  The pulmonary findings are similar to those described in past pandemics. Secondary fungal and viral infections, which have not been reported previously, were noted. Although the number of cases in this study is small, the findings reinforce the notion that changes in extrapulmonary organs are attributable to multiorgan dysfunction syndrome rather than a viral cytopathic effect, and that there is no transplacental transmission of virus. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5539731 Sun, 25 Dec 2011 17:27:03 +0100 5539731 http://www.medworm.com/index.php?rid=5539730&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04085.x Conclusions:  OPN expression is a valuable marker for diagnosis of atypical meningioma and prediction of grades I and II meningioma recurrence. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5539730 Sun, 25 Dec 2011 17:27:02 +0100 5539730 http://www.medworm.com/index.php?rid=5539729&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04096.x Conclusions:  Estimation of specific type of macrophages, of the M1 and M2 types, is superior to the estimation of TAMs as a whole (CD68+ cells) for prediction of the prognosis of DLBCL patients. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5539729 Sun, 25 Dec 2011 17:27:00 +0100 5539729 http://www.medworm.com/index.php?rid=5539728&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04089.x Conclusions:  Some genetically and morphologically complicated cases of ocular adnexal IgG4‐related disease emphasize the need for in‐depth studies to differentiate this disease from MALT lymphoma, and to exclude secondary lymphoma. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5539728 Sun, 25 Dec 2011 17:26:59 +0100 5539728 http://www.medworm.com/index.php?rid=5539727&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04086.x Conclusions:  NNKTCL is classically an aggressive lymphoma, but the intramucosal variant is less aggressive. Loss of ETS‐1 or T‐bet correlated weakly with invasion, a finding that requires further confirmation. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5539727 Sun, 25 Dec 2011 17:26:57 +0100 5539727 http://www.medworm.com/index.php?rid=5539726&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04091.x Conclusions:  In core needle biopsies, IMP3 expression seems to be of limited use as a single marker for the diagnosis of HCC, given a sensitivity of 52%, but it may be helpful in combination with other markers. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5539726 Sun, 25 Dec 2011 17:26:56 +0100 5539726 http://www.medworm.com/index.php?rid=5539725&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04094.x Conclusions:  At the time of transplantation cirrhotic livers have different ranges of collagen proportionate area, according to aetiology. R lobe fibrosis corresponds with L lobe fibrosis. The range of fibrosis within each aetiological group could be useful for prognostic subclassification. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5539725 Sun, 25 Dec 2011 17:26:54 +0100 5539725 http://www.medworm.com/index.php?rid=5539724&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04078.x Conclusions:  This study suggests that a disease entity which can be named follicular cholangitis and pancreatitis exists and may be under‐recognized. The disease mainly affects the hilar bile ducts and pancreatic head in adults. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5539724 Sun, 25 Dec 2011 17:26:52 +0100 5539724 http://www.medworm.com/index.php?rid=5539723&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04082.x Conclusions:  DMBT1 may play an important role in the proliferation of HPCs in HBV‐related liver diseases. Moreover, down‐expression of DMBT1 might enhance the risk of malignant transformation of HPCs. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5539723 Sun, 25 Dec 2011 17:26:51 +0100 5539723 http://www.medworm.com/index.php?rid=5539722&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04132.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5539722 Sun, 25 Dec 2011 17:26:48 +0100 5539722 http://www.medworm.com/index.php?rid=5539721&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04092.x Conclusions:  Pathologists can recognize NK SCC with good agreement, and when a pathologist classifies a tumour as NK SCC, this reliably predicts p16 positivity. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5539721 Sun, 25 Dec 2011 17:26:12 +0100 5539721 http://www.medworm.com/index.php?rid=5516613&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04042.x Brenn T 
(2011) HistopathologyPitfalls in the evaluation of melanocytic lesionsThe pathology of melanocytic tumours remains one of the most challenging and controversial fields in diagnostic histopathology, and it is one of the leading causes for litigation against pathologists. This is due largely to the wide morphological spectrum and often only subtle differentiating features with potential for both under‐ as well as overdiagnosis of melanoma. Particular pitfalls include the diagnosis of rare and unusual melanoma variants and melanoma resembling naevi. Furthermore, a subset of benign naevi may show concerning features associated more typically with a diagnosis of melanoma. These features include irregular junctional components with pagetoid spread, melanocyte atypia, lack of dermal ... Histopathology journals http://www.medworm.com/rss/comments.php?id=5516613 Fri, 16 Dec 2011 05:00:00 +0100 5516613 http://www.medworm.com/index.php?rid=5516612&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04062.x Conclusion:  Our findings may reflect a high rate of DNA repair due to frequent tissue injury during the lifetime of these individuals, and also more advanced disease presentation in this population with worse prognosis. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5516612 Fri, 16 Dec 2011 05:00:00 +0100 5516612 http://www.medworm.com/index.php?rid=5507259&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04024.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5507259 Wed, 14 Dec 2011 05:00:00 +0100 5507259 http://www.medworm.com/index.php?rid=5507258&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04057.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5507258 Wed, 14 Dec 2011 05:00:00 +0100 5507258 http://www.medworm.com/index.php?rid=5507257&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04059.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5507257 Wed, 14 Dec 2011 05:00:00 +0100 5507257 http://www.medworm.com/index.php?rid=5507256&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04064.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5507256 Wed, 14 Dec 2011 05:00:00 +0100 5507256 http://www.medworm.com/index.php?rid=5507255&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04066.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5507255 Wed, 14 Dec 2011 05:00:00 +0100 5507255 http://www.medworm.com/index.php?rid=5507254&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04061.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5507254 Wed, 14 Dec 2011 05:00:00 +0100 5507254 http://www.medworm.com/index.php?rid=5507253&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04065.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5507253 Wed, 14 Dec 2011 05:00:00 +0100 5507253 http://www.medworm.com/index.php?rid=5507252&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04067.x Conclusions:  In the era of personalized and tailored therapies, we suggest that patients affected by the classical lobular subtype of breast carcinoma constantly lack the ad hoc predictive rationale for receiving common chemotherapy that includes anthracyclines. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5507252 Wed, 14 Dec 2011 05:00:00 +0100 5507252 http://www.medworm.com/index.php?rid=5516637&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04131.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5516637 Thu, 01 Dec 2011 05:00:00 +0100 5516637 http://www.medworm.com/index.php?rid=5516636&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04084.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5516636 Thu, 01 Dec 2011 05:00:00 +0100 5516636 http://www.medworm.com/index.php?rid=5516635&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04113.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5516635 Thu, 01 Dec 2011 05:00:00 +0100 5516635 http://www.medworm.com/index.php?rid=5516634&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04060.x Conclusions:  Our results suggest that podoplanin expression by CAFs could be an unfavourable prognostic marker for IDC. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5516634 Thu, 01 Dec 2011 05:00:00 +0100 5516634 http://www.medworm.com/index.php?rid=5516633&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04073.x Conclusions:  These results imply: (i) that there is a loss of SFRP‐2 expression from benign to malignant prostate glands; and (ii) differential SFRP‐2 expression among two possible subgroups of Gleason grade 5 tumours. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5516633 Thu, 01 Dec 2011 05:00:00 +0100 5516633 http://www.medworm.com/index.php?rid=5516632&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04074.x Conclusions:  Carbonic anhydrase IX is a sensitive marker for clear cell RCC in core biopsies. However, other genitourinary or adrenal tumours that can have a clear cell appearance including urothelial, squamous cell, clear cell adeno and adrenal cortical carcinoma and Sertoli cell tumour express CAIX. Knowledge of expression overlap between these entities may prevent incorrect interpretation of immunohistochemical results, particularly if limited tissue is available. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5516632 Thu, 01 Dec 2011 05:00:00 +0100 5516632 http://www.medworm.com/index.php?rid=5516631&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04051.x Conclusions:  Several fibrosis‐related factors are greatly altered in severely dystrophic skeletal muscle. Osteopontin was the most conspicuously upregulated, both as transcript and as protein, in muscle fibres and infiltrating cells, indicating an intimate involvement in fibrosis, and also in inflammation and muscle regeneration, although its precise roles in these processes remain to be elucidated. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5516631 Thu, 01 Dec 2011 05:00:00 +0100 5516631 http://www.medworm.com/index.php?rid=5516630&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04050.x Conclusions:  MPP represents a distinct histopathological variant with biological and prognostic significance. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5516630 Thu, 01 Dec 2011 05:00:00 +0100 5516630 http://www.medworm.com/index.php?rid=5516629&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04054.x Conclusions:  In adequately sampled tumors, DLBCL can be associated with NLPHL at diagnosis. Diffuse architecture, loss of FDC networks, sometimes immunophenotype shift are characteristics of DLBCL associated with NLPHL. Treatment with R‐CHOP usually leads to CR. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5516629 Thu, 01 Dec 2011 05:00:00 +0100 5516629 http://www.medworm.com/index.php?rid=5516628&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04047.x Conclusions:  These cases probably represent a solid form of systemic EBV‐positive T‐cell lymphoproliferative disease of childhood, which requires identification and the development of appropriate therapy. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5516628 Thu, 01 Dec 2011 05:00:00 +0100 5516628 http://www.medworm.com/index.php?rid=5516627&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04069.x Conclusions:  Our study shows that, according to current criteria, Lennert’s lymphoma is a rare but distinctive entity among epithelioid cell‐rich lymphomas, differing on grounds of morphology and immunophenotype from other PTCL subtypes. An additional finding is the broad morphological spectrum of epithelioid‐cell rich PTCLs showing a TFH cell phenotype. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5516627 Thu, 01 Dec 2011 05:00:00 +0100 5516627 http://www.medworm.com/index.php?rid=5516626&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04045.x Conclusions:  Our findings suggest that Dock180 contributes to ovarian carcinogenesis and dissemination and is a potential prognostic marker and therapeutic target. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5516626 Thu, 01 Dec 2011 05:00:00 +0100 5516626 http://www.medworm.com/index.php?rid=5516625&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04046.x Conclusions:  Compared to manual cell counting, computer‐aided image analysis yields more reproducible results for the assessment of uNK cells density using IHC. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5516625 Thu, 01 Dec 2011 05:00:00 +0100 5516625 http://www.medworm.com/index.php?rid=5516624&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04053.x Conclusion:  In the absence of TCN, an infiltrative margin is a major factor related to the potential for aggressive behaviour of MLMS. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5516624 Thu, 01 Dec 2011 05:00:00 +0100 5516624 http://www.medworm.com/index.php?rid=5516623&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04070.x Conclusions:  Dedifferentiated leiomyosarcoma has morphological parallels with other types of dedifferentiated sarcoma, and is clinically aggressive. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5516623 Thu, 01 Dec 2011 05:00:00 +0100 5516623 http://www.medworm.com/index.php?rid=5516622&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04049.x Conclusion:  While the reappraised spectrum of AIDS‐MTs does not demonstrate divergent subtype‐determined clinical behaviour, heightened awareness/recognition of this expanded spectrum will not only promote improved diagnosis of pleomorphic and myopericytic variants, which may be the sentinel clue to AIDS and its comorbidity, but will also facilitate distinction from histopathological mimics in specific anatomic locations. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5516622 Thu, 01 Dec 2011 05:00:00 +0100 5516622 http://www.medworm.com/index.php?rid=5516621&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04056.x Conclusions:  Tumour growth in pancreatic head cancers is more dispersed than in RC, particularly in the tumour periphery. Revision of the R1 definition for pancreatic head cancer may therefore need to be considered. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5516621 Thu, 01 Dec 2011 05:00:00 +0100 5516621 http://www.medworm.com/index.php?rid=5516620&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04048.x Conclusions:  Bile ducts in PSC show two distinct dysplasia–carcinoma sequences as evidenced by differences in cell morphology, growth patterns, immunophenotypes and grade of malignancy. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5516620 Thu, 01 Dec 2011 05:00:00 +0100 5516620 http://www.medworm.com/index.php?rid=5516619&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04058.x Conclusions:  The carcinogenesis of ICC arising in CALD and the ICC component of HC‐CC, each showing similar features, may involve hepatic progenitor cells. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5516619 Thu, 01 Dec 2011 05:00:00 +0100 5516619 http://www.medworm.com/index.php?rid=5516618&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04055.x Conclusions:  Conservative treatments, such as endoscopic resection, should not be used for gastric carcinoma with IMPC components, as these cases are associated with a high propensity for lymphovascular invasion and nodal metastasis. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5516618 Thu, 01 Dec 2011 05:00:00 +0100 5516618 http://www.medworm.com/index.php?rid=5516617&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04071.x Conclusions:  WT GISTs have different genomic profiles from both mutated GISTs and murine mature ICCs. Considering that IGF1R expression is common to both WT GISTs and putative precursor ICCs, this study suggests that WT GISTs may derive either from ICCs at a different step of differentiation or from a different cell of origin. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5516617 Thu, 01 Dec 2011 05:00:00 +0100 5516617 http://www.medworm.com/index.php?rid=5516616&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04044.x Conclusions:  In patients with clinicopathological stage C colonic cancer, GST Pi expression is associated with features of tumour aggressiveness and with reduced overall survival. Further appropriately designed studies should aim to discover whether GST Pi can predict response to adjuvant chemotherapy. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5516616 Thu, 01 Dec 2011 05:00:00 +0100 5516616 http://www.medworm.com/index.php?rid=5516615&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04043.x Conclusion:  Compared to CC, SAC displayed more HG‐TB, HG‐CyPs and fewer PLI at the invasive margins and this may account for its poorer clinical outcome. TB, CyPs, TGP and PLI are useful histological prognostic aids in SAC. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5516615 Thu, 01 Dec 2011 05:00:00 +0100 5516615 http://www.medworm.com/index.php?rid=5516614&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04114.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5516614 Thu, 01 Dec 2011 05:00:00 +0100 5516614 http://www.medworm.com/index.php?rid=5516611&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04090.x Conclusions:  In order to support the work of pathologists adequately, digital microscopy systems need to provide support for a range of activities beyond viewing slides. Digital microscopy systems should support multitasking, while also providing flexibility so that pathologists can adapt their use of the technology to their own working patterns. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5516611 Thu, 01 Dec 2011 05:00:00 +0100 5516611 http://www.medworm.com/index.php?rid=5460321&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04022.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5460321 Tue, 29 Nov 2011 05:00:00 +0100 5460321 http://www.medworm.com/index.php?rid=5390971&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03983.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5390971 Thu, 10 Nov 2011 05:00:00 +0100 5390971 http://www.medworm.com/index.php?rid=5390970&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04001.x Conclusions:  Distinct inflammatory and granulomatous processes in the parathyroid gland are rare. Scanty lymphocytic infiltrates are common, and occur in generalized inflammatory conditions or venous congestion. We note the surprising absence of an association between histological proof of parathyroiditis and hypoparathyroidism. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5390970 Thu, 10 Nov 2011 05:00:00 +0100 5390970 http://www.medworm.com/index.php?rid=5390969&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04006.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5390969 Thu, 10 Nov 2011 05:00:00 +0100 5390969 http://www.medworm.com/index.php?rid=5390968&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04010.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5390968 Thu, 10 Nov 2011 05:00:00 +0100 5390968 http://www.medworm.com/index.php?rid=5507251&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04068.x Conclusions:  Advanced stage AIDS patients showed a depletion of LCs in the tongue mucosa. HIV infection induces cytopathic changes in LCs, contributing to their depletion regardless of the presence of oral infections. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5507251 Tue, 01 Nov 2011 04:00:00 +0100 5507251 http://www.medworm.com/index.php?rid=5460320&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04018.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5460320 Tue, 01 Nov 2011 04:00:00 +0100 5460320 http://www.medworm.com/index.php?rid=5424259&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04077.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5424259 Tue, 01 Nov 2011 04:00:00 +0100 5424259 http://www.medworm.com/index.php?rid=5424258&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04075.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5424258 Tue, 01 Nov 2011 04:00:00 +0100 5424258 http://www.medworm.com/index.php?rid=5424257&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04076.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5424257 Tue, 01 Nov 2011 04:00:00 +0100 5424257 http://www.medworm.com/index.php?rid=5424256&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04008.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5424256 Tue, 01 Nov 2011 04:00:00 +0100 5424256 http://www.medworm.com/index.php?rid=5424255&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04009.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5424255 Tue, 01 Nov 2011 04:00:00 +0100 5424255 http://www.medworm.com/index.php?rid=5424254&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04015.x Conclusion:  The MAS‐01 antiserum will facilitate rapid identification of tissue mycobacterial infection by histopathologists. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5424254 Tue, 01 Nov 2011 04:00:00 +0100 5424254 http://www.medworm.com/index.php?rid=5424253&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04037.x Conclusions:  dc‐CISH is a promising alternative to FISH in HER2 testing, and the single‐institute incidence of HER2 amplification in breast cancer in Taiwan is 21.2%. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5424253 Tue, 01 Nov 2011 04:00:00 +0100 5424253 http://www.medworm.com/index.php?rid=5424252&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04034.x Conclusion:  Our study shows that the PATHWAY® HER2 antibody can bind HER4 peptides and fusion proteins in three different experimental settings. This should be investigated further to determine whether binding of HER4 also occurs in tissue samples and if such binding would have implications for therapy decisions for breast cancer patients. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5424252 Tue, 01 Nov 2011 04:00:00 +0100 5424252 http://www.medworm.com/index.php?rid=5424251&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04040.x Conclusions:  In breast cancer, a predominance of tumour‐infiltrating CD8+ over FoxP3+ cells was observed in MBC. Thus, the ratio of CD8+ to FoxP3+ cells rather than the absolute number of intratumoral FoxP3+ cells may be predictive for the clinical outcome of cancer. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5424251 Tue, 01 Nov 2011 04:00:00 +0100 5424251 http://www.medworm.com/index.php?rid=5424250&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04036.x Conclusions:  There is an overlap between the immunophenotype of mesothelial cells and that of basal‐like carcinomas of breast. Positive calretinin and CK5/6 are not specific, and may be seen in both mesothelial cells and basal‐like breast carcinomas. Negative ER and PR of basal carcinomas may also bias the observer against a breast origin. However, other negative mesothelial markers, such as WT1 and thrombomodulin, may help point to the correct diagnosis. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5424250 Tue, 01 Nov 2011 04:00:00 +0100 5424250 http://www.medworm.com/index.php?rid=5424249&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04031.x Conclusions:  Fifteen per cent of breast carcinomas stain with calretinin. These tumours are more likely to be high‐grade, ER‐negative, and display a basal‐like phenotype. These tumours may be misdiagnosed as malignant mesothelioma when they metastasize to the pleura. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5424249 Tue, 01 Nov 2011 04:00:00 +0100 5424249 http://www.medworm.com/index.php?rid=5424248&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04032.x Conclusions:  Interobserver agreement of the B‐categorization scheme was high and was modified by referral status, level of radiological suspicion of breast cancer, breast density, imaging guidance of core biopsies and requirement of additional immunohistological staining. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5424248 Tue, 01 Nov 2011 04:00:00 +0100 5424248 http://www.medworm.com/index.php?rid=5424247&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04038.x Conclusions:  Chronic chorioamnionitis is a common pathologic feature in unexplained preterm fetal death. This novel finding suggests that cellular and antibody‐mediated anti‐fetal rejection of the mother is associated with fetal death (graft failure) in human pregnancy. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5424247 Tue, 01 Nov 2011 04:00:00 +0100 5424247 http://www.medworm.com/index.php?rid=5424246&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04028.x Conclusion:  Expression of PR and ESR1 defines a subgroup of ovarian carcinomas with a favourable prognosis. PR and ESR1 mRNA expression analysis is a sensitive, quantitative and easy‐to‐perform high‐throughput analytical tool for the identification of this subgroup and could be predictive in clinical trials focused on patients with potential benefit from hormonal treatment. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5424246 Tue, 01 Nov 2011 04:00:00 +0100 5424246 http://www.medworm.com/index.php?rid=5424245&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04029.x Conclusions:  The assessment of cytoplasmic ERβ expression could be helpful to identify poor prognosis in elderly patients with non‐HPV‐related vulvar squamous cell carcinoma (SCC). (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5424245 Tue, 01 Nov 2011 04:00:00 +0100 5424245 http://www.medworm.com/index.php?rid=5424244&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04014.x Conclusions:  These data suggest that LNAB histology is more accurate than FNAC cytology for the preoperative selection of HCN. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5424244 Tue, 01 Nov 2011 04:00:00 +0100 5424244 http://www.medworm.com/index.php?rid=5424243&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04013.x Conclusions:  The RP‐DT model, constructed with eight protein markers for estimating lymphatic metastasis risk in pN0 lung SCC, is clinically feasible and practical, using IHC data from the primary tumour. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5424243 Tue, 01 Nov 2011 04:00:00 +0100 5424243 http://www.medworm.com/index.php?rid=5424242&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04016.x Conclusion:  PCH‐like lesions can occur infrequently as an incidental finding in SPVC, rarely accompanying ossifying fibrocapillary micronodules. These lesions are considered to be a secondary form of PCH, representing severely tortuous and proliferative capillary changes rather than neoplasia. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5424242 Tue, 01 Nov 2011 04:00:00 +0100 5424242 http://www.medworm.com/index.php?rid=5424241&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04011.x Conclusions:  We found BilIN in the large bile ducts of hepatitis B virus‐ and hepatitis C virus‐related LC as well as in cases related to a biliary aetiology. The LC group was significantly less likely to show changes in the expression of MUC5AC and proliferative activity than the biliary group. Alterations in p16 and p21 reflected increasing degrees of dysplasia in both groups. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5424241 Tue, 01 Nov 2011 04:00:00 +0100 5424241 http://www.medworm.com/index.php?rid=5424240&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04027.x Conclusions:  Assessment of colorectal carcinoma phenotypes of invasion can be learnt and performed with confidence, and their prognostic impact is confirmed in this independent series. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5424240 Tue, 01 Nov 2011 04:00:00 +0100 5424240 http://www.medworm.com/index.php?rid=5424239&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04019.x Conclusion:  This study has provided powerful information on the implication of a diagnosis of FAC. In a small but not inconsiderable case number, the ultimate diagnosis will be chronic inflammatory bowel disease. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5424239 Tue, 01 Nov 2011 04:00:00 +0100 5424239 http://www.medworm.com/index.php?rid=5424238&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04035.x Conclusion:  Nuclear grade could be a new and useful morphological predictor for high malignant potential in PGA. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5424238 Tue, 01 Nov 2011 04:00:00 +0100 5424238 http://www.medworm.com/index.php?rid=5424237&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04017.x Conclusions:  Human epidermal growth factor receptor 2 status in gastric carcinoma is comparable to previous studies with good concordance between IHC and SISH; all IHC 2+ and unusual patterns should be assessed with ISH studies; heterogeneity of tumour HER2 overexpression/amplification is common with possible implications for HER2 testing; and HER2 overexpression appears sufficiently specific to be considered a potential diagnostic biomarker of dysplasia. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5424237 Tue, 01 Nov 2011 04:00:00 +0100 5424237 http://www.medworm.com/index.php?rid=5424236&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04012.x Conclusions:  These findings suggest that the discordant HER2 amplification observed in metastatic lesions is explained substantially by heterogeneity within primary tumours. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5424236 Tue, 01 Nov 2011 04:00:00 +0100 5424236 http://www.medworm.com/index.php?rid=5350365&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03994.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5350365 Tue, 25 Oct 2011 04:00:00 +0100 5350365 http://www.medworm.com/index.php?rid=5350364&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03996.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5350364 Tue, 25 Oct 2011 04:00:00 +0100 5350364 http://www.medworm.com/index.php?rid=5350363&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03997.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5350363 Tue, 25 Oct 2011 04:00:00 +0100 5350363 http://www.medworm.com/index.php?rid=5325879&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03889.x Nogales FF, Preda O & Nicolae A
(2011) HistopathologyYolk sac tumours revisited. A review of their many faces and namesWe review the current knowledge on human yolk sac tumours (YSTs) 50 years after their initial description. Their complex nomenclature and histogenesis stress the fact that they are not a discrete entity, but represent a multifaceted group of neoplasms, for which the term primitive endodermal tumours would be more appropriate, accounting for their capacity to differentiate into various extraembryonal and somatic cell types. Different histological patterns of human YSTs correlate with the developmental potential of primitive endoderm and mesenchyme, but they are also similar to some murine experimental tumours. Exceptionally, YSTs replicate the tubular structures of ... Histopathology journals http://www.medworm.com/rss/comments.php?id=5325879 Tue, 18 Oct 2011 04:00:00 +0100 5325879 http://www.medworm.com/index.php?rid=5325878&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03911.x Shelley‐Fraser G, Borley N R, Warren B F & Shepherd N A
(2011) HistopathologyThe connective tissue changes of Crohn’s diseaseAlthough the inflammatory pathology of Crohn’s disease is manifestly its most important attribute, the connective tissue changes are important in the genesis of the more chronic features of the disease, and yet these have received little attention from clinicians, pathologists, and scientists. Fat‐wrapping appears to be pathognomonic of Crohn’s disease, and is an important marker of disease for surgeons. There is evidence of a complex interplay between the effector inflammatory cells of Crohn’s disease and adipocytes, hyperplasia of which results in fat‐wrapping. Pathologically, this is exhibited in the close relationship between the transmural in... Histopathology journals http://www.medworm.com/rss/comments.php?id=5325878 Tue, 18 Oct 2011 04:00:00 +0100 5325878 http://www.medworm.com/index.php?rid=5325877&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03959.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5325877 Tue, 18 Oct 2011 04:00:00 +0100 5325877 http://www.medworm.com/index.php?rid=5325876&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03971.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5325876 Tue, 18 Oct 2011 04:00:00 +0100 5325876 http://www.medworm.com/index.php?rid=5325875&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03973.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5325875 Tue, 18 Oct 2011 04:00:00 +0100 5325875 http://www.medworm.com/index.php?rid=5325874&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03982.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5325874 Tue, 18 Oct 2011 04:00:00 +0100 5325874 http://www.medworm.com/index.php?rid=5325873&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03984.x Senetta R, Paglierani M & Massi D
(2011) HistopathologyFluorescence in‐situ hybridization analysis for melanoma diagnosisMelanocytic proliferation constitutes a heterogeneous group of lesions with remarkable differences in their biology and clinical outcome. Thus, accurate histological diagnosis of these cases is mandatory to establish the most appropriate surgical treatment and follow‐up. Although histological examination alone is usually sufficient to identify melanomas among the greater number of nevi, the definition of the benign or malignant nature of a subset of melanocytic tumours, exhibiting atypical features, is a challenging task. Novel techniques that may assist in the histopathological diagnosis in difficult cases have been extensively researched over recent years. Fl... Histopathology journals http://www.medworm.com/rss/comments.php?id=5325873 Tue, 18 Oct 2011 04:00:00 +0100 5325873 http://www.medworm.com/index.php?rid=5325872&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03995.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5325872 Tue, 18 Oct 2011 04:00:00 +0100 5325872 http://www.medworm.com/index.php?rid=5288136&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03972.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5288136 Tue, 04 Oct 2011 04:00:00 +0100 5288136 http://www.medworm.com/index.php?rid=5390967&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04023.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5390967 Sat, 01 Oct 2011 04:00:00 +0100 5390967 http://www.medworm.com/index.php?rid=5350362&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03998.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5350362 Sat, 01 Oct 2011 04:00:00 +0100 5350362 http://www.medworm.com/index.php?rid=5338843&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.04026.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5338843 Sat, 01 Oct 2011 04:00:00 +0100 5338843 http://www.medworm.com/index.php?rid=5338842&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03952.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5338842 Sat, 01 Oct 2011 04:00:00 +0100 5338842 http://www.medworm.com/index.php?rid=5338841&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03956.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5338841 Sat, 01 Oct 2011 04:00:00 +0100 5338841 http://www.medworm.com/index.php?rid=5338840&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03979.x Conclusions:  GISTs occasionally show CD10 immunopositivity (especially small intestinal spindle cell GISTs), and infrequently show focal EMA positivity. GISTs do not show immunopositivity for ERa or HMB45. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5338840 Sat, 01 Oct 2011 04:00:00 +0100 5338840 http://www.medworm.com/index.php?rid=5338839&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03884.x Conclusions:  ALDH1 expression in carcinoma cells is an independent prognostic factor in TN breast cancer patients. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5338839 Sat, 01 Oct 2011 04:00:00 +0100 5338839 http://www.medworm.com/index.php?rid=5338838&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03993.x Conclusions:  The present findings suggest that ESC‐associated pathways are activated in human gliomas and that these may be involved in glioma progression, a role that is distinct from that in ESCs. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5338838 Sat, 01 Oct 2011 04:00:00 +0100 5338838 http://www.medworm.com/index.php?rid=5338837&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03992.x Conclusions:  These data suggest that there are early and fundamental differences in cell kinetics between the reactive PNEC proliferation that occurs in response to pulmonary injury and that seen in the pre‐neoplastic condition of DIPNECH. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5338837 Sat, 01 Oct 2011 04:00:00 +0100 5338837 http://www.medworm.com/index.php?rid=5338836&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03937.x Conclusions:  The threshold for distinguishing minor extracapsular invasion with good prognosis from wide extracapsular invasion with poor prognosis is 5 mm. The worse prognosis for CEPA associated with recurrent PA indicates the necessity for close surveillance of patients with recurrent PA. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5338836 Sat, 01 Oct 2011 04:00:00 +0100 5338836 http://www.medworm.com/index.php?rid=5338835&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03989.x Conclusions:  Comparison of two systems of substaging pT1 bladder cancer shows that measurement of the size of infiltrating tumour area by HPFs may improve risk stratification. An infiltrative growth pattern on the invasion front should be documented in the pathological report, indicating a worse outcome. Additional studies are needed to find further parameters detecting high‐risk tumours. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5338835 Sat, 01 Oct 2011 04:00:00 +0100 5338835 http://www.medworm.com/index.php?rid=5338834&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03988.x Conclusions:  DSC2 staining offers high sensitivity (96%) and high specificity (100%) for the detection of squamous differentiation in UC. DSC2 is a useful immunohistochemical marker for separation of UC with squamous differentiation from pure UC. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5338834 Sat, 01 Oct 2011 04:00:00 +0100 5338834 http://www.medworm.com/index.php?rid=5338833&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03987.x Conclusions:  Circulation of virtual images of biopsy material is a suitable alternative to glass slide‐based schemes for the evaluation of diagnostic consistency. The majority of participants agreed that the ability to evaluate limited diagnostic material outweighed the disadvantages of a virtual system. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5338833 Sat, 01 Oct 2011 04:00:00 +0100 5338833 http://www.medworm.com/index.php?rid=5338832&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03986.x Conclusions:  Maximal RD dichotomized at one HPF is an objective method to subdivide EPE and a strong, independent predictor for BCR after RP. Its use is recommended for substaging pT3a in future TNM classifications. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5338832 Sat, 01 Oct 2011 04:00:00 +0100 5338832 http://www.medworm.com/index.php?rid=5338831&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03981.x Conclusions:  This study shows that: (i) historical material can be still employed usefully, and (ii) the FTH‐phenotype corresponds to a broad spectrum of PTCLs that might form a new category to be validated in future molecular and clinicopathological analyses. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5338831 Sat, 01 Oct 2011 04:00:00 +0100 5338831 http://www.medworm.com/index.php?rid=5338830&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03978.x Conclusions:  MYC protein expression detected by immunohistochemistry using a commercially available antibody correlates with MYC gene translocation, and could be used as a screening tool to select those cases in which confirmatory genetic testing is mandatory. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5338830 Sat, 01 Oct 2011 04:00:00 +0100 5338830 http://www.medworm.com/index.php?rid=5338829&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03976.x Conclusions:  ENKTL (≤50 years) is distinct from that in elderly patients and may encompass ANKL and overlap in the clinicopathological profile with NK‐cell type CAEBV/TNK‐LPD. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5338829 Sat, 01 Oct 2011 04:00:00 +0100 5338829 http://www.medworm.com/index.php?rid=5338828&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03980.x Conclusions:  Stratifying patient outcome by final regression grade after step section did not yield different outcomes in patients with initial pCR. If residual tumour cells are not identified on initial meticulous examination, further processing of step sections is not necessary. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5338828 Sat, 01 Oct 2011 04:00:00 +0100 5338828 http://www.medworm.com/index.php?rid=5338827&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03991.x Conclusions:  High TLR‐9 expression is associated with poor differentiation, a high proliferation rate and disseminated disease. Accordingly, increased TLR‐9 expression may contribute to the growth and metastatic properties of oesophageal adenocarcinoma. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5338827 Sat, 01 Oct 2011 04:00:00 +0100 5338827 http://www.medworm.com/index.php?rid=5338826&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03941.x Conclusions:  This study suggests that abnormal expression of Nek2 and β‐catenin might be one of the mechanisms of tumorigenesis, especially of abnormal tumour proliferation. They may represent new potential targets for therapeutic intervention. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5338826 Sat, 01 Oct 2011 04:00:00 +0100 5338826 http://www.medworm.com/index.php?rid=5338825&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03940.x Conclusions:  There is a high propensity for metastatic NETs to mimic primary breast carcinomas. Careful attention to cytological and architectural features can help to identify cases that require further immunophenotypic workup with a panel of tissue‐specific antibodies. However, clinical history is paramount for optimal diagnosis. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5338825 Sat, 01 Oct 2011 04:00:00 +0100 5338825 http://www.medworm.com/index.php?rid=5338824&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03917.x Conclusion:  The presence of fibroblasts with nuclear β‐catenin in tumours is a good prognostic indicator, although in the context of tissue culture models these cells can increase the growth and metastatic potential of cancer cells. These apparently paradoxical observations underline the complexity of epithelial–stromal signalling within tumours and highlight an area for further study. (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5338824 Sat, 01 Oct 2011 04:00:00 +0100 5338824 http://www.medworm.com/index.php?rid=5240973&cid=s_28438_32_f&fid=28438&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1365-2559.2011.03944.x (Source: Histopathology) Histopathology journals http://www.medworm.com/rss/comments.php?id=5240973 Wed, 21 Sep 2011 04:00:00 +0100 5240973