MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'IET Nanobiotechnology' source. Sun, 21 Mar 2010 17:37:49 +0100 http://www.medworm.com/index.php?rid=3378348&cid=s_37228_174_f&fid=37228&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Fisnumber%3D5417135%26arnumber%3D5417138 This study proposes a diagonally based growth scheme that is applicable to these templates of interconnects (as an example). Differently from previous techniques (mostly sequential in execution), growth is allowed along two different directions in the aggregate, thus permitting a parallel mode of operation. This is made possible by utilising a tile set and binding scheme to allow multiple seed tiles to grow along the main diagonal of the pattern. The conditions by which this type of new growth is possible at a reduced error occurrence in mismatched tiles, are presented; error tolerance is achieved by employing healing and so-called robust generation of the seed tiles, thus ensuring that pattern growth is controlled along both directions. Simulation results are presented under different sce... IET Nanobiotechnology journals http://www.medworm.com/rss/comments.php?id=3378348 Mon, 01 Mar 2010 00:00:00 +0100 3378348 http://www.medworm.com/index.php?rid=3378347&cid=s_37228_174_f&fid=37228&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Fisnumber%3D5417135%26arnumber%3D5417137 To establish the quantitative model of the dragonfly wing the reconfiguration and nanoindentation technique were used. The mechanical properties of wings were measured by nanoindentre. Generally, the costa undertake is mainly pressure, and its mechanical properties should be the largest. However, in the nanoindentation test, the largest value of the reduced modulus (Er) and hardness (H) mainly appear in the radius, except the value at 0.7L (L is the wing length). The Er and H of the forewing were larger than that of the hindwing, except the value at 0.7L. The reversing engineering (3-D scanner) and AutoCAD were cooperated to reconfigure the dragonfly wing. Then the material parameters and skeleton transforms to a finite element analysis. The quantitative models were discussed in static ran... IET Nanobiotechnology journals http://www.medworm.com/rss/comments.php?id=3378347 Mon, 01 Mar 2010 00:00:00 +0100 3378347 http://www.medworm.com/index.php?rid=3378346&cid=s_37228_174_f&fid=37228&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Fisnumber%3D5417135%26arnumber%3D5417136 Bovine serum albumin (BSA) protein adsorption on thin spun films of different metal octakishexylthiophthalocyanine [(C6S)8PcM, M=Cu, Ni] derivatives is investigated by using three independent spectroscopic measurements namely Raman spectroscopy, ellipsometry and surface plasmon resonance imaging. Thermally induced molecular self-reorganisations in the phthalocyanine films are found to have produced the changes in the surface energy which, in turn, control protein adsorption. The amount of BSA adsorption on [(C6S)8PcNi] is more limited than that on [(C6S)8PcCu] and this observation is consistent with the results on the surface wettability obtained from the contact angle measurements. The shift from the plasmonic resonance wavelength because of the BSA adsorption was significantly larger for... IET Nanobiotechnology journals http://www.medworm.com/rss/comments.php?id=3378346 Mon, 01 Mar 2010 00:00:00 +0100 3378346 http://www.medworm.com/index.php?rid=3007997&cid=s_37228_174_f&fid=37228&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Fisnumber%3D5335581%26arnumber%3D5335583 Poly (lactic-co-glycolic acid) (PLGA) was used as a co-emulsifier in the preparation of insulin-loaded solid lipid nanoparticles (SLN) with hydrogenated castor oil as lipid matrix and lecithin as surfactant by doubleemulsion technique. The effects of PLGA on the preparation and hypoglycaemic activity of insulin-loaded SLN were studied. The results showed that with the supplement of PLGA, the encapsulation efficiency and loading capacity were increased significantly from 79.08±1.62 to 85.57±3.21% and 1.58±0.03 to 1.71±0.06%, whereas the surface charge and particle size were changed insignificantly from -25.87±2.65 to -22.67±1.19 mv and 431.0±16.1 to 397.0±68.0 nm, respectively. In vivo studies demonstrated that PLGA increased t... IET Nanobiotechnology journals http://www.medworm.com/rss/comments.php?id=3007997 Thu, 19 Nov 2009 16:37:47 +0100 3007997 http://www.medworm.com/index.php?rid=3007996&cid=s_37228_174_f&fid=37228&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Fisnumber%3D5335581%26arnumber%3D5335582 This study proposes an efficient and improved model of a direct storage bidirectional memory, improved bidirectional associative memory (IBAM), and emphasises the use of nanotechnology for efficient implementation of such large-scale neural network structures at a considerable lower cost reduced complexity, and less area required for implementation. This memory model directly stores the X and Y associated sets of M bipolar binary vectors in the form of (M X Nx) and (M X Ny) memory matrices, requires O(N ) or about 30% of interconnections with weight strength ranging between ±1, and is computationally very efficient as compared to sequential, intraconnected and other bidirectional associative memory (BAM) models of outer-product type that require O(N 2) complex interconnections with... IET Nanobiotechnology journals http://www.medworm.com/rss/comments.php?id=3007996 Thu, 19 Nov 2009 16:37:47 +0100 3007996 http://www.medworm.com/index.php?rid=2681816&cid=s_37228_174_f&fid=37228&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Fisnumber%3D5196648%26arnumber%3D5196651 Surface plasmon resonance imaging (SPRI) is a useful tool for the study of surface biomolecular interactions allowing for label-free detection and elegant instrumentation. SPRI imaging system is described in this review with an emphasis on recent applications with examples of different biological interactions and high throughput analysis. Signal amplification in SPRI using nanoparticle and waveguide-based optical coupling is introduced. Finally the detection sensitivity of the SPRI system is examined in terms of other competitive methods. (Source: IET Nanobiotechnology) IET Nanobiotechnology journals http://www.medworm.com/rss/comments.php?id=2681816 Sat, 08 Aug 2009 12:28:45 +0100 2681816 http://www.medworm.com/index.php?rid=2681815&cid=s_37228_174_f&fid=37228&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Fisnumber%3D5196648%26arnumber%3D5196650 This theoretical model predicts that the activity of multiple enzymes may be controlled simultaneously with superior efficiency in nanosized reactors by adjusting pH. Multistep enzymatic processes employed for various purposes including organic biotransformation may require application of multiple reactions and isolation of intermediates. Sequential activity switching would offer substantial advantages. Nanoreactors would provide better option to fully appreciate the pH switching approach. (Source: IET Nanobiotechnology) IET Nanobiotechnology journals http://www.medworm.com/rss/comments.php?id=2681815 Sat, 08 Aug 2009 12:28:45 +0100 2681815 http://www.medworm.com/index.php?rid=2681814&cid=s_37228_174_f&fid=37228&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Fisnumber%3D5196648%26arnumber%3D5196649 A mathematical model based on finite-element technique is developed for predicting the transport and capture of multiple magnetic nanoparticles in a microfluidic system that consists of a microfluidic channel enclosed by a permanent magnet. The trajectories and trapping efficiencies are calculated for multiple magnetic nanoparticles when released in the microsystem. It is demonstrated that not only the size but also the point of release of nanoparticles within the microchannel affects the capturing process. Influence of three important parameters, inlet velocities of fluid containing magnetic nanoparticles, diameter of magnetic nanoparticles and magnetic field strength on the trapping efficiency are investigated and optimised values of inlet velocity and magnetic field strength for complet... IET Nanobiotechnology journals http://www.medworm.com/rss/comments.php?id=2681814 Sat, 08 Aug 2009 12:28:42 +0100 2681814 http://www.medworm.com/index.php?rid=2509562&cid=s_37228_174_f&fid=37228&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Fisnumber%3D5071423%26arnumber%3D5071427 This study reports an investigation of hyperthermia cancer therapy utilising an alternating magnetic field to induce a localised temperature increase on tumours by using injectable magnetic nanoparticles. Invitro and in-vivo experiments represent the feasibility of hyperthermia cancer therapy. A feedback temperature control system was first developed to keep the nanoparticles at a constant temperature to prevent overheating in the tumours such that a safer and more precise cancer therapy becomes feasible. By using the feedback temperature control system, magnetic nanoparticles can be heated up to the specific constant temperatures, 37, 40, 42, 45, 46 and 47°C, respectively, with a variation less than 0.2°C. With this approach, the in-vitro survival rate of tumour cells at d... IET Nanobiotechnology journals http://www.medworm.com/rss/comments.php?id=2509562 Sun, 31 May 2009 23:00:00 +0100 2509562 http://www.medworm.com/index.php?rid=2509561&cid=s_37228_174_f&fid=37228&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Fisnumber%3D5071423%26arnumber%3D5071426 The physical properties of DNA are quite important for molecular genetics as well as for its nanotechnological applications. Studying the interactions of alternating current (AC) electric fields with deoxyribonucleic acid (DNA) allows one to draw conclusions about these properties. These interactions are usually investigated in two different ways. In dielectric spectroscopy, a DNA solution is placed in a homogeneous AC field and electronic parameters are measured over several frequency decades in the Hz to GHz range. These electronic data are then interpreted on the basis of physico-chemical models as a result of certain phenomena on the molecular level. In dielectrophoretic studies, a DNA solution is exposed to an inhomogeneous AC field and the spatial response of few or single molecules ... IET Nanobiotechnology journals http://www.medworm.com/rss/comments.php?id=2509561 Sun, 31 May 2009 23:00:00 +0100 2509561 http://www.medworm.com/index.php?rid=2509560&cid=s_37228_174_f&fid=37228&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Fisnumber%3D5071423%26arnumber%3D5071425 Novel carboxyl group-decorated crosslinked polystyrene nanoparticles were prepared via the soapless emulsion polymerisation of styrene and divinyl benzene with oleic acid as functional comonomer. The existence of the surface carboxyl group was verified by zeta potential analysis. Particle sizes of the functional nanoparticles prepared with the proposed method were found to be in the range of 60¿100 nm by transmission electron microscopy and dynamic light scattering analyses. Functionalised nanoparticles are proposed as carriers for biomolecules or drugs. (Source: IET Nanobiotechnology) IET Nanobiotechnology journals http://www.medworm.com/rss/comments.php?id=2509560 Sun, 31 May 2009 23:00:00 +0100 2509560 http://www.medworm.com/index.php?rid=2509559&cid=s_37228_174_f&fid=37228&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Fisnumber%3D5071423%26arnumber%3D5071424 In this study, the authors propose a new bacteria detection method using a carbon nanotube (CNT) gas sensor and a microheater, which were coupled into a Bio-MEMS (microelectromechanical systems)-type device. Bacteria were heated by the microheater in air so that ammonia (NH3) gas can be generated by the oxidation reaction of organic components of bacteria. Thus generated NH3 gas was detected by using the CNT gas sensor, which was fabricated by dielectrophoresis (DEP) and combined with the microheater to form a small chamber. Cyclic pulsed heating operation was employed so that the CNT response to elevated temperature did not mask NH3 response. It was demonstrated that the proposed device could detect and quantify 107 bacteria cells (Escherichia coli). Possible application of DEP to trap an... IET Nanobiotechnology journals http://www.medworm.com/rss/comments.php?id=2509559 Sun, 31 May 2009 23:00:00 +0100 2509559 http://www.medworm.com/index.php?rid=2261764&cid=s_37228_174_f&fid=37228&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Fisnumber%3D4785875%26arnumber%3D4785877 Biomimetic polymeric nanofibres are of great interest in tissue engineering and wound repair because of their structural similarity to extracellular matrix. In this work, biomimetic chitosan-based nanofibres with various diameters were prepared by ionically cross-linking with tripolyphosphate (TPP) in adipic acid medium and characterised using transmission electron microscopy, X-ray diffraction and Fourier-transform infrared spectroscopy. Using dexamethasone sodium phosphate (DMP) and bovine serum albumin (BSA) as low and high molecular-weight bioactive molecule models, respectively, drug loading and in vitro release behaviours of chitosan-TPP nanofibres were investigated. The drug-loaded chitosan-TPP nanofibres showed a prolonged release profile with three distinct stages in physiological... IET Nanobiotechnology journals http://www.medworm.com/rss/comments.php?id=2261764 Sat, 14 Mar 2009 04:00:00 +0100 2261764 http://www.medworm.com/index.php?rid=2261763&cid=s_37228_174_f&fid=37228&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Fisnumber%3D4785875%26arnumber%3D4785876 Capillary electrophoresis is a cornerstone of lab-on-a-chip (LOC) implementations for medical diagnostics. However, the infrastructure needed to operate electrophoretic LOC implementations tends to be large and expensive, hindering the development of portable or low-cost systems. A custom-designed and highly integrated microelectronic chip for high-voltage generation switching and interfacing is recently developed. Here, the authors integrate the microelectronic chip with a microfluidic chip, a solid-state laser, filter, lens and several dollars worth of electronic components to form an inexpensive and portable platform, which is the size of a mobile telephone. This compact system has such reduced power requirements that the complete platform can be operated using a universal serial bus li... IET Nanobiotechnology journals http://www.medworm.com/rss/comments.php?id=2261763 Sat, 14 Mar 2009 04:00:00 +0100 2261763 http://www.medworm.com/index.php?rid=1976676&cid=s_37228_174_f&fid=37228&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Fisnumber%3D4674770%26arnumber%3D4674772 The authors present the use of electric-field constriction created by a microfabricated structure to realise high-yield electrofusion of biological cells. The method uses an orifice on an electrically insulating wall (orifice plate) whose diameter is as small as that of the cells. Owing to the field constriction created by the orifice, we can induce the controlled magnitude of membrane voltage selectively around the contact point, regardless of the cell size. The field constriction also ensures 1:1 fusion even when more than two cells are forming a chain at the orifice. A device for electrofusion has been made with a standard SU-8 lithography and PDMS molding, and real-time observation of the electrofusion process is made. Experiments using plant protoplasts or mammalian cells show that th... IET Nanobiotechnology journals http://www.medworm.com/rss/comments.php?id=1976676 Fri, 21 Nov 2008 14:35:39 +0100 1976676 http://www.medworm.com/index.php?rid=1976675&cid=s_37228_174_f&fid=37228&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Fisnumber%3D4674770%26arnumber%3D4674771 An assessment of the effectiveness of healing for error tolerance in DNA self-assembly tile sets for algorithmic/nano-manufacturing applications is presented. Initially, the conditions for correct binding of a tile to an existing aggregate are analysed using a Markovian approach; based on this analysis, it is proved that correct aggregation (as identified with a so-called ideal tile set) is not always met for the existing tile sets for nano-manufacturing. A metric for assessing tile sets for healing by utilising punctures is proposed. Tile sets are investigated and assessed with respect to features such as error (mismatched tile) movement, punctured area and bond types. Subsequently, it is shown that the proposed metric can comprehensively assess the healing effectiveness of a puncture typ... IET Nanobiotechnology journals http://www.medworm.com/rss/comments.php?id=1976675 Fri, 21 Nov 2008 14:35:38 +0100 1976675 http://www.medworm.com/index.php?rid=1906622&cid=s_37228_174_f&fid=37228&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Fisnumber%3D4607232%26arnumber%3D4607235 A wireless power transfer and communication system based on near-field inductive coupling has been designed and implemented. The feasibility of using such a system to remotely control drug release from an implantable drug delivery system is addressed. The architecture of the wireless system is described and the signal attenuation over distance in both water and phosphate buffered saline is studied. Additionally, the health risk due to exposure to radio frequency (RF) radiation is examined using a biological model. The experimental results demonstrate that the system can trigger the release of drug within 5 s, and that such short exposure to RF radiation does not produce any significant ( les1degC) heating in the biological model. The conclusion of the work is that this system could replace... IET Nanobiotechnology journals http://www.medworm.com/rss/comments.php?id=1906622 Sat, 25 Oct 2008 14:28:04 +0100 1906622 http://www.medworm.com/index.php?rid=1906621&cid=s_37228_174_f&fid=37228&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Fisnumber%3D4607232%26arnumber%3D4607234 The estimation of the membrane voltage and the polarisation factor of biological cells provide a base for the study of bio-manipulation techniques, such as dielectrophoresis, electroporation or electrofusion. To model a biological cell, an ellipsoidal particle with an insulating membrane is sometimes employed, but due to the limitation of the confocal nature of the coordinate system, the membrane thickness is assumed to vary with the position, despite the fact that the lipid bilayer membrane has a uniform thickness. The authors present a method to rigorously treat the uniform-thickness condition in a system having an axial symmetry. The method is based on the harmonic expansion of the field, to include the condition of the uniform- membrane thickness as a series expansion of the geometrica... IET Nanobiotechnology journals http://www.medworm.com/rss/comments.php?id=1906621 Sat, 25 Oct 2008 14:28:04 +0100 1906621 http://www.medworm.com/index.php?rid=1906620&cid=s_37228_174_f&fid=37228&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Fisnumber%3D4607232%26arnumber%3D4607233 Innovations in microfabricated analytical devices integrated with microelectronic circuits and biological cells show promising results in detection, diagnosis and analysis. Planar metallic microelectrodes are widely used for the electrical interface with the biological cells. Issues with the current microelectrode array design are the difficulty in selective integration with a cell, the size dependency of its impedance and the large amount of noise in the circuit due to this mismatch. It is quite evident that an approach utilising nanotechnology can solve some of these problems by yielding efficient electrical interconnections. The design and development of a planar microelectrode array integrated with vertically aligned nanowires for lab-on-a- chip (LoC) device applications are presented.... IET Nanobiotechnology journals http://www.medworm.com/rss/comments.php?id=1906620 Sat, 25 Oct 2008 14:28:04 +0100 1906620 http://www.medworm.com/index.php?rid=1603578&cid=s_37228_174_f&fid=37228&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Fisnumber%3D4531111%26arnumber%3D4531114 A nanoscale sensor employing fluorescent resonance energy transfer interactions between fluorescent quantum dots (QDs) and organic quencher molecules can be used for the multiplexed detection of biological antigens in solution. Detection occurs when the antigens to be detected displace quencher-labelled inactivated (or dead) antigens of the same type attached to QD-antibody complexes through equilibrium reactions. This unquenches the QDs, allowing detection to take place through the observation of photoluminescence in solution or through the fluorescence imaging of unquenched QD complexes trapped on filter surfaces. Multiplexing can be accomplished by using several different sizes of QDs, with each size QD labelled with an antibody for a different antigen, providing the ability to detect s... IET Nanobiotechnology journals http://www.medworm.com/rss/comments.php?id=1603578 Tue, 10 Jun 2008 04:00:00 +0100 1603578 http://www.medworm.com/index.php?rid=1603577&cid=s_37228_174_f&fid=37228&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Fisnumber%3D4531111%26arnumber%3D4531113 A recirculating microfluidic platform has been developed for carrying out optical bio-detection. The present device can be used for passive mixing of the biological species with the microfluidic channel without immobilisation, through appropriate design and flow control. The feasibility of bio-detection using the present setup has been demonstrated through the method of fluorescence and the experiments were carried out with Antisheep Antibody (AB) tagged with Alexafluor 647 (AF647) fluorophore particles. By controlling the fluid flow, it was possible to isolate AB separately into a recirculation zone within the microfluidic channel, thereby enabling qualitative and quantitative bio-detection. Finite element modelling of the flow behaviour has been carried out and the results were similar t... IET Nanobiotechnology journals http://www.medworm.com/rss/comments.php?id=1603577 Tue, 10 Jun 2008 04:00:00 +0100 1603577 http://www.medworm.com/index.php?rid=1603576&cid=s_37228_174_f&fid=37228&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Fisnumber%3D4531111%26arnumber%3D4531112 Dielectrophoretic forces, generated by radio-frequency voltages applied to micromachined, transparent, indium tin oxide electrodes, have been used to condense suspensions of insulinoma cells (BETA-TC-6 and INS-1) into a 10times10 array of three-dimensional cell constructs. Some of these constructs, measuring ~150 mum in diameter, 120 mum in height and containing around 1000 cells, were of the same size and cell density as a typical islet of Langerhans. With the dielectrophoretic force maintained, these engineered cell constructs were able to withstand mechanical shock and fluid flow forces. Reproducibility of the process required knowledge of cellular dielectric properties, in terms of membrane capacitance and membrane conductance, which were obtained by electrorotation measurements. The a... IET Nanobiotechnology journals http://www.medworm.com/rss/comments.php?id=1603576 Tue, 10 Jun 2008 04:00:00 +0100 1603576 http://www.medworm.com/index.php?rid=1567490&cid=s_37228_174_f&fid=37228&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Fisnumber%3D4459255%26arnumber%3D4459257 (Source: IET Nanobiotechnology) IET Nanobiotechnology journals http://www.medworm.com/rss/comments.php?id=1567490 Mon, 03 Mar 2008 05:00:00 +0100 1567490 http://www.medworm.com/index.php?rid=1567489&cid=s_37228_174_f&fid=37228&url=http%3A%2F%2Fieeexplore.ieee.org%2Fxpls%2Fabs_all.jsp%3Fisnumber%3D4459255%26arnumber%3D4459256 (Source: IET Nanobiotechnology) IET Nanobiotechnology journals http://www.medworm.com/rss/comments.php?id=1567489 Mon, 03 Mar 2008 05:00:00 +0100 1567489