MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Infection' source. Sat, 20 Mar 2010 14:27:49 +0100 http://www.medworm.com/index.php?rid=3375994&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw260246578331608%2F We describe a rare case of multifocal necrotizing fasciitis (NF) complicating a single vaccine injection. Injection of hepatitis B vaccine of a 16-year-old immunocompetent woman developed into rapidly spreading multifocal NF of the right arm and the thighs, with septic shock. Treatment with antimicrobial therapy and surgical debridements allowed amputation to be avoided with a favourable outcome. The etiological agent was a methicillin-sensitive Staphylococcus aureus (MSSA) isolate harboring the Panton-Valentine leukocidin (PVL) and five enterotoxins. PVL has recently been reported in large series of methicillin-resistant SA cases and has been associated with necrotizing infections. Some strains of MSSA could harbor PVL and enterotoxins. PCR investigation is not frequent but could imp... Infection journals http://www.medworm.com/rss/comments.php?id=3375994 Tue, 16 Mar 2010 14:49:44 +0100 3375994 http://www.medworm.com/index.php?rid=3371755&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv2wj430hl3t63126%2F Conclusion  The data obtained regarding MRSA prevention measures should stimulate infection control professionals to pursue further initiatives. Particularly, the vigorous MRSA management in countries with decreasing MRSA proportions should encourage hospitals to implement preventive measures in order to reduce the spread of MRSA. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-010-0001-8Authors S. Hansen, Charité–University Medicine Berlin Institute for Hygiene and Environmental Medicine Campus Benjamin Franklin, Hindenburgdamm 27 12203 Berlin GermanyF. Schwab, Charité–University Medicine Berlin Institute for Hygiene and Environmental Medicine Campus Benjamin Franklin, Hindenburgdamm 27 12203 Berlin GermanyA. Asensio, ... Infection journals http://www.medworm.com/rss/comments.php?id=3371755 Mon, 15 Mar 2010 17:56:23 +0100 3371755 http://www.medworm.com/index.php?rid=3364672&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn3q1607180x0312k%2F Conclusion  In comparison to international benchmarks, the markedly high rate of CL-BSI, the high rate of VAP and the resistance patterns of major infecting pathogens identified in this study emphasize the need to improve current practices for appropriate use and management of invasive devices in Cypriot ICUs. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-010-0007-2Authors A. Gikas, University Hospital of Heraklion Infection Control Unit 1352/71110 Crete GreeceM. Roumbelaki, University Hospital of Heraklion Infection Control Unit 1352/71110 Crete GreeceD. Bagatzouni-Pieridou, Nicosia General Hospital Microbiology Department Nicosia CyprusM. Alexandrou, Limassol General Hospital Microbiology Laboratory Limassol CyprusV. Zini... Infection journals http://www.medworm.com/rss/comments.php?id=3364672 Fri, 12 Mar 2010 06:48:57 +0100 3364672 http://www.medworm.com/index.php?rid=3360879&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq0433173p021u110%2F Conclusion  VAP due to CRAB and excess use of intravascular devices are the most important risk factors for CRAB bacteremia in our ICU. Severity of organ failure and WBC count at A. baumannii bacteremia onset are independently associated with mortality. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-010-0008-1Authors C. Routsi, Evangelismos Hospital, University of Athens Medical School 1st Department of Intensive Care 45-47 Ipsilantou Str. 106 76 Athens GreeceM. Pratikaki, Evangelismos Hospital, University of Athens Medical School 1st Department of Intensive Care 45-47 Ipsilantou Str. 106 76 Athens GreeceE. Platsouka, Evangelismos Hospital Department of Clinical Microbiology Athens GreeceC. Sotiropoulou, Evangelismos Hospital... Infection journals http://www.medworm.com/rss/comments.php?id=3360879 Thu, 11 Mar 2010 18:14:45 +0100 3360879 http://www.medworm.com/index.php?rid=3356188&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp02433r232724k86%2F Content Type Journal ArticleCategory ErratumDOI 10.1007/s15010-010-3067-4Authors O. Kaya, Suleyman Demirel University Faculty of Medicine Dept. of Infectious Diseases and Clinical Microbiology Çünür, Isparta 32260 TurkeyF. Z. Akcam, Suleyman Demirel University Faculty of Medicine Dept. of Infectious Diseases and Clinical Microbiology Çünür, Isparta 32260 TurkeyC. Uyar, Suleyman Demirel University Faculty of Medicine Dept. of Infectious Diseases and Clinical Microbiology Çünür, Isparta 32260 TurkeyM. Tuz, Suleyman Demirel University Faculty of Medicine Dept. of Ear, Nose, and Throat, Head & Neck Surgery Çünür, Isparta TurkeyN. Kapucuoglu, Suleyman Demirel University Faculty of Medicine Dept. of Pathology Çünür, Isparta Turkey Journal InfectionOnline ISSN 1439-0973P... Infection journals http://www.medworm.com/rss/comments.php?id=3356188 Wed, 10 Mar 2010 15:29:06 +0100 3356188 http://www.medworm.com/index.php?rid=3356187&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy5451l0540776618%2F We report two cases of severe pneumonia in hematological patients due to Kytococcus schroeteri, a saprophyte of the human skin. When blood cultures or respiratory specimens yield micrococcus-like colonies, Kytococcus species, which are often resistant to penicillin, should be considered and the antimicrobial therapy should be adjusted accordingly. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s15010-009-9295-4Authors C. J. Hodiamont, Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center Dept. of Medical Microbiology, Room L1-245 Meibergdreef 9 1105 AZ Amsterdam The NetherlandsC. Huisman, Center for Infection and Immunity Amsterdam (CINIMA), Academic Medical Center Dept. of Hematology Amsterdam The NetherlandsL. Spanjaard, Center for Infection a... Infection journals http://www.medworm.com/rss/comments.php?id=3356187 Wed, 10 Mar 2010 15:29:06 +0100 3356187 http://www.medworm.com/index.php?rid=3356190&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn0304257172j7292%2F Content Type Journal ArticleDOI 10.1007/s15010-009-9333-7Authors D. Tappe, University of Würzburg Institute of Hygiene and Microbiology Josef-Schneider-Str. 2 97080 Würzburg GermanyP. Demmer, University of Würzburg Institute of Pathology Würzburg GermanyU. Echterhoff, Private Practice Massener Hellweg Unna GermanyR. Weskamp, Institute of Pathology Unna Germany Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126 (Source: Infection) Infection journals http://www.medworm.com/rss/comments.php?id=3356190 Wed, 10 Mar 2010 15:29:04 +0100 3356190 http://www.medworm.com/index.php?rid=3356189&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx426g4q536556366%2F We report a 23-year-old female patient with cystic fibrosis developing severe intravascular hemolysis with a minimal hemoglobin level of 1.6 g/dl after 7 days of treatment with piperacillin, consistent with an immune-mediated hemolytic crisis. Twenty days later, the patient could leave the hospital in good condition without any neurological deficit. To our knowledge, this is the lowest reported hemoglobin value caused by hemolytic anemia with intact survival. As piperacillin is commonly used in patients with cystic fibrosis, it is important to monitor the full-blood counts of patients during treatment with piperacillin and to be aware of the potential for hemolytic anemia to develop. Anti-piperacillin antibodies should be considered whenever these patients develop hemolytic... Infection journals http://www.medworm.com/rss/comments.php?id=3356189 Wed, 10 Mar 2010 15:29:04 +0100 3356189 http://www.medworm.com/index.php?rid=3356191&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F681q2k4146815j6q%2F We report a girl with mild Mycobacterium bovis Bacille Calmette–Guérin (BCG) disease and Salmonella enteritidis cervical lymphadenitis. Despite treatment, she has remained a fecal carrier of S. enteritidis for the past 14 years. She was found to have complete IL-12/IL-23Rβ1 deficiency. A homozygous r.518G>C IL12RB1 mutation was identified, leading to a non-functional R173P substitution in the IL-12/IL-23Rβ1 protein. This mutation abrogated IL-12/IL-23Rβ1 cell-surface expression and resulted in complete lack of T cell responsiveness to both IL-12 and IL-23. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s15010-009-9222-0Authors E. van de Vosse, Leiden University Medical Center Department of Infectious Diseases Albinusdreef 2 2333 ZA Leiden The NetherlandsT... Infection journals http://www.medworm.com/rss/comments.php?id=3356191 Wed, 10 Mar 2010 15:29:03 +0100 3356191 http://www.medworm.com/index.php?rid=3336725&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F758367u443712223%2F We present a rare case of BKV-associated hemorrhagic cystitis in a 48-year-old man with AIDS and previously diagnosed progressive multifocal leukoencephalopathy. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s15010-009-9201-5Authors A. N. Kinnaird, University of Texas Health Science Center at San Antonio Dept. of Medicine San Antonio TX USAG. M. Anstead, South Texas Veterans Healthcare System Dept. of Medicine, Division of Infectious Diseases San Antonio TX USA Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126 (Source: Infection) Infection journals http://www.medworm.com/rss/comments.php?id=3336725 Wed, 03 Mar 2010 08:52:08 +0100 3336725 http://www.medworm.com/index.php?rid=3324575&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F731n322p40558m05%2F Abstract  The administration of antibiotics by the inhaled route is a widely recognized treatment in patients with cystic fibrosis (CF) and bronchiectasis. Tobramycin solution for inhalation (TOBI) has been available for many years and is licensed in the USA and Europe. While strong data support the use of aerosolized antibiotics for the treatment of respiratory infections in patients with CF or bronchiectasis, only a few clinical studies have examined the role of aerosolized antibiotics in the treatment of pneumonia, including ventilator-associated pneumonia (VAP) in these patients. During the last decade increasing interest has been directed towards alternative treatments to the systemic administration of antimicrobial agents for the treatment of patients with hospital-ac... Infection journals http://www.medworm.com/rss/comments.php?id=3324575 Mon, 01 Mar 2010 06:47:43 +0100 3324575 http://www.medworm.com/index.php?rid=3324576&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe135224558835538%2F Conclusions  We conclude that MRSA rapid screening techniques must be interpreted cautiously in a low-prevalence population, as the sensitivity is lower than in selected high-risk populations. MRSA carriers detected with molecular techniques must be confirmed by conventional culture methods for follow-up. The specificity and negative predictive value indicate that molecular rapid methods are worthwhile to be considered in MRSA-preventive strategies. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-009-9117-0Authors E. Nulens, General Hospital Sint-Jan AV Brugge-Oostende Medical Microbiology Ruddershove 10 8000 Brugge BelgiumP. Descheemaeker, General Hospital Sint-Jan AV Brugge-Oostende Medical Microbiology Ruddershove 10 8000... Infection journals http://www.medworm.com/rss/comments.php?id=3324576 Mon, 01 Mar 2010 06:47:42 +0100 3324576 http://www.medworm.com/index.php?rid=3324577&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm38734558k460485%2F Conclusions  Infectious spondylodiscitis affects most frequently the elderly population, who are more exposed to healthcare contacts. Consequently, the infection etiology includes a growing proportion of multi-resistant bacteria and fungi. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-009-9340-8Authors C. D’Agostino, University “La Sapienza” Rome Dept. of Infectious Diseases and Tropical Medicine Rome ItalyL. Scorzolini, University “La Sapienza” Rome Dept. of Infectious Diseases and Tropical Medicine Rome ItalyA. P. Massetti, University “La Sapienza” Rome Dept. of Infectious Diseases and Tropical Medicine Rome ItalyM. Carnevalini, University “La Sapienza” Rome Dept. of Infectious Diseases and Tropical Medic... Infection journals http://www.medworm.com/rss/comments.php?id=3324577 Mon, 01 Mar 2010 06:47:41 +0100 3324577 http://www.medworm.com/index.php?rid=3224072&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq0187274v732772w%2F Conclusions  The increase of MDR in A. baumannii isolates from 2002 to 2006 in four hospitals suggests that clinicians in Germany may expect a rising proportion of MDR in A. baumannii isolates among inpatients. The antimicrobial susceptibility testing of A. baumannii isolates against recommended drugs, combined with in-house antimicrobial resistance surveillance, is needed to ensure appropriate treatment. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-009-9225-xAuthors M. Wadl, Robert Koch-Institute Postgraduate Training for Applied Epidemiology (PAE, German Field Epidemiology Training Programme), Dept. for Infectious Disease Epidemiology DGZ-Ring 1 13086 Berlin GermanyK. Heckenbach, Robert Koch-Institute Dept. for Infectiou... Infection journals http://www.medworm.com/rss/comments.php?id=3224072 Thu, 28 Jan 2010 07:01:42 +0100 3224072 http://www.medworm.com/index.php?rid=3224073&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F832820v08138045l%2F Conclusions  The major risk factors for infections due to ESBL-producing bacteria were travel in high-prevalence countries, prior antibiotic use, and mechanical ventilation during a stay in the intensive care unit. Community-acquired infections were documented in 17% of the patients. An early identification of risk factors is crucial to providing the patients an optimal empiric antibiotic therapy and to keep the use of carbapenems to a minimum. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-009-9207-zAuthors S. P. Kuster, University of Zurich Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich Raemistrasse 100 8091 Zurich SwitzerlandB. Hasse, University of Zurich Division of Infectious Dise... Infection journals http://www.medworm.com/rss/comments.php?id=3224073 Thu, 28 Jan 2010 07:01:41 +0100 3224073 http://www.medworm.com/index.php?rid=3289456&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc33j6hp728804437%2F This articleaims to increase the awareness and understanding of druginducedliver injury (DILI) due to antibacterial drugs. Itreviews the pattern of antibacterial DILI and provides detailson molecular mechanisms and toxicogenomics, as well asclinical data based on epidemiology studies. Certain antibacterialdrugs are more frequently linked to hepatotoxicity thanothers. Therefore, the hepatotoxic potential of tetracyclines,sulfonamides, tuberculostatic agents, macrolides, quinolones,and beta-lactams are discussed in more detail. Efforts toimprove the early detection of DILI and the acquisition ofhigh-quality epidemiological data are pivotal for increasedpatient safety. Content Type Journal ArticleCategory ReviewDOI 10.1007/s15010-009-9179-zAuthors J. M. Leitner, Medical Universit... Infection journals http://www.medworm.com/rss/comments.php?id=3289456 Wed, 27 Jan 2010 20:29:35 +0100 3289456 http://www.medworm.com/index.php?rid=3224074&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc33j6hp728804437%2F This article aims to increase the awareness and understanding of drug-induced liver injury (DILI) due to antibacterial drugs. It reviews the pattern of antibacterial DILI and provides details on molecular mechanisms and toxicogenomics, as well as clinical data based on epidemiology studies. Certain antibacterial drugs are more frequently linked to hepatotoxicity than others. Therefore, the hepatotoxic potential of tetracyclines, sulfonamides, tuberculostatic agents, macrolides, quinolones, and beta-lactams are discussed in more detail. Efforts to improve the early detection of DILI and the acquisition of high-quality epidemiological data are pivotal for increased patient safety. Content Type Journal ArticleCategory ReviewDOI 10.1007/s15010-009-9179-zAuthors J. M. Leitner, Medi... Infection journals http://www.medworm.com/rss/comments.php?id=3224074 Wed, 27 Jan 2010 20:29:35 +0100 3224074 http://www.medworm.com/index.php?rid=3224075&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu1p041lq87844n20%2F Content Type Journal ArticleCategory EditorialDOI 10.1007/s15010-009-9350-6Authors B. Huttner, University of Geneva Hospitals and Medical School Infection Control Program Geneva SwitzerlandS. Harbarth, University of Geneva Hospitals and Medical School Infection Control Program Geneva Switzerland Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126 (Source: Infection) Infection journals http://www.medworm.com/rss/comments.php?id=3224075 Wed, 27 Jan 2010 20:29:34 +0100 3224075 http://www.medworm.com/index.php?rid=3224076&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F3n85170044746r54%2F Conclusions  Outpatient antibiotic use in the population insured by “Clalit Health Services” declined between 2003 and 2005. Children had the highest consumption rates. There were large differences in antibiotic use between geographic regions, and diabetes mellitus was the only variable significantly associated with antibiotic use. We therefore conclude that most of the differences in antibiotic use are likely due to doctor preferences, local routines, and patients’ attitudes and expectations. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-009-9065-8Authors O. Nitzan, Haemek Medical Center Internal Medicine Ward C Afula IsraelM. Low, TLV Medical Center Information Unit Tel Aviv IsraelI. Lavi, Carmel Medical Center Dep... Infection journals http://www.medworm.com/rss/comments.php?id=3224076 Wed, 27 Jan 2010 20:29:32 +0100 3224076 http://www.medworm.com/index.php?rid=3086732&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F7h4105564942087g%2F Conclusions  This study documents that P. aeruginosa bacteremic disease is responsible for a significant burden of illness in general populations and identifies those groups at increased risk of infection and subsequent mortality. This information can be used to identify those individuals likely to benefit from empiric anti-pseudomonal therapies. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-009-9145-9Authors M. D. Parkins, Calgary Health Region Division of Infectious Disease, Dept. of Medicine Calgary Alberta CanadaD. B. Gregson, Calgary Health Region Division of Infectious Disease, Dept. of Medicine Calgary Alberta CanadaJ. D. D. Pitout, University of Calgary, Calgary Health Region Dept. of Pathology and Laboratory Medicine... Infection journals http://www.medworm.com/rss/comments.php?id=3086732 Sun, 13 Dec 2009 06:42:00 +0100 3086732 http://www.medworm.com/index.php?rid=3086733&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq474485579273137%2F Conclusions  Prior piperacillin/tazobactam and empiric cephalosporin use were the independent risk factors of MDR-PM strains. All MDR-PM urinary isolates at our institution were ESBL producers. Therefore, carbapenem use remains the only available treatment option for MDR-PM isolates in our institution. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-009-8460-5Authors K. Cohen-Nahum, Soroka University Medical Center and the Faculty of Health Sciences Infectious Diseases Institute Beer-Sheva IsraelL. Saidel-Odes, Soroka University Medical Center and the Faculty of Health Sciences Infectious Diseases Institute Beer-Sheva IsraelK. Riesenberg, Soroka University Medical Center and the Faculty of Health Sciences Infectious Diseases In... Infection journals http://www.medworm.com/rss/comments.php?id=3086733 Thu, 10 Dec 2009 00:12:33 +0100 3086733 http://www.medworm.com/index.php?rid=3080769&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd5826086431w2290%2F Content Type Journal ArticleCategory CorrespondenceDOI 10.1007/s15010-009-9199-8Authors Ch. Neocleous, University of Thessalia Dept. of Microbiology, Medical School Larissa GreeceA. Damani, University of Thessalia Dept. of Microbiology, Medical School Larissa GreeceI. Gerogianni, University of Thessalia Dept. of Respiratory Medicine, Medical School Larissa GreeceK. Gourgoulianis, University of Thessalia Dept. of Microbiology, Medical School Papakyriazi 22 Larissa GreeceE. Petinaki, University of Thessalia Dept. of Microbiology, Medical School Papakyriazi 22 Larissa Greece Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126 (Source: Infection) Infection journals http://www.medworm.com/rss/comments.php?id=3080769 Wed, 09 Dec 2009 06:48:13 +0100 3080769 http://www.medworm.com/index.php?rid=3032136&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fgpx1625123818167%2F Content Type Journal ArticleCategory CorrespondenceDOI 10.1007/s15010-009-9049-8Authors H. R. Kim, Chung-Ang University College of Medicine Dept. of Laboratory Medicine Seoul KoreaJ. W. Kim, Chung-Ang University Yongsan Hospital Dept. of Internal Medicine 45-207 Hangangno 3-ga Yongsan-gu, Seoul 140-757 KoreaM. K. Lee, Chung-Ang University College of Medicine Dept. of Laboratory Medicine Seoul KoreaJ. G. Kim, Chung-Ang University College of Medicine Dept. of Internal Medicine Seoul Korea Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126 (Source: Infection) Infection journals http://www.medworm.com/rss/comments.php?id=3032136 Mon, 23 Nov 2009 17:08:39 +0100 3032136 http://www.medworm.com/index.php?rid=3032137&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy6r2n00868080384%2F Conclusion  Our study reveals that resistance rates have been increasing during the last decade. Published resistance rates may lack information due to important differences regarding age, gender, and probable origin of the isolates. Empirical therapy for UTI should be guided more on individual risk profile and local resistance data than on resistance data banks. Content Type Journal ArticleCategory Brief ReportDOI 10.1007/s15010-009-8457-0Authors L. Blaettler, University Hospital Basel Division of Infectious Diseases and Hospital Epidemiology Petersgraben 4 4031 Basel SwitzerlandD. Mertz, University Hospital Basel Division of Infectious Diseases and Hospital Epidemiology Petersgraben 4 4031 Basel SwitzerlandR. Frei, University Hospital Basel Microbiology Laboratory Ba... Infection journals http://www.medworm.com/rss/comments.php?id=3032137 Mon, 23 Nov 2009 17:08:37 +0100 3032137 http://www.medworm.com/index.php?rid=2986778&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F45v387772420276x%2F This article presents the recommendations for the diagnosis and management of osteomyelitis and prosthetic joint infections in adults developed by Bone and Joint Infections Committee for the Italian Society of Infectious and Tropical Diseases. It contains data published through to November 2007. An evidence-based scoring system that is used by the Infectious Diseases Society of America was applied to treatment recommendations. Content Type Journal ArticleCategory ReviewDOI 10.1007/s15010-009-8269-2Authors S. Esposito, Seconda Università di Napoli Dipartimento Malattie Infettive Naples ItalyS. Leone, U.O.C. Malattie Infettive, A.O.R.N. “San Giuseppe Moscati” Avellino ItalyM. Bassetti, A.O.U. San Martino Clinica Malattie Infettive Genova ItalyS. Borrè, A.S.O. “Maggiore della ... Infection journals http://www.medworm.com/rss/comments.php?id=2986778 Wed, 11 Nov 2009 06:57:29 +0100 2986778 http://www.medworm.com/index.php?rid=2986777&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc64w3837g4551320%2F Content Type Journal ArticleCategory EditorialDOI 10.1007/s15010-009-3609-9Authors C. Ruef Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126 (Source: Infection) Infection journals http://www.medworm.com/rss/comments.php?id=2986777 Wed, 11 Nov 2009 06:57:29 +0100 2986777 http://www.medworm.com/index.php?rid=2986779&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk28132321kr7284p%2F Conclusions  Essential to the management of patients with hematological malignancies undergoing chemotherapy are surveillance and prophylaxis of HBV infection together with prompt administration of nucleoside/nucleotide analogs in cases of reactivation and/or seroreversion. Content Type Journal ArticleCategory Brief ReportDOI 10.1007/s15010-009-9019-1Authors D. Francisci, University of Perugia Division of Infectious Diseases, Dept. of Experimental Medicine and Biochemical Science Ospedale “Santa Maria della Misericordia”, P.zzle Menghini 1 06132 Perugia ItalyF. Falcinelli, University of Perugia Section of Hematology and Clinical Immunology, Dept. of Clinical and Experimental Medicine Perugia ItalyE. Schiaroli, University of Perugia Division of Infectious Diseases, D... Infection journals http://www.medworm.com/rss/comments.php?id=2986779 Wed, 11 Nov 2009 06:57:27 +0100 2986779 http://www.medworm.com/index.php?rid=2986782&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2752564k345t65pg%2F Conclusions  The overall influenza vaccination coverage among subjects who suffer from asthma in Spain is very low. Special attention should be paid to children, younger adults, and smokers, since these subjects have the lowest adherence to vaccine recommendations. Strategies focused on health-care providers and patients must be urgently implemented to improve influenza vaccination coverage among asthma sufferers. Content Type Journal ArticleCategory Brief ReportDOI 10.1007/s15010-009-9069-4Authors R. Jiménez-García, Rey Juan Carlos University Unity of Teaching and Research in Preventive Medicine and Public Health, Faculty of Health Sciences Avda de Atenas s/n 28402 Alcorcón, Madrid SpainV. Hernández-Barrera, Rey Juan Carlos University Unity of Teaching and Resear... Infection journals http://www.medworm.com/rss/comments.php?id=2986782 Wed, 11 Nov 2009 06:57:25 +0100 2986782 http://www.medworm.com/index.php?rid=2986781&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2825113w28206752%2F Content Type Journal ArticleCategory CorrespondenceDOI 10.1007/s15010-009-9092-5Authors A. Douglas, University of Melbourne School of Medicine Parkville VIC 3010 AustraliaP. Harris, Townsville Hospital Pathology Queensland 100 Angus Smith Drive Douglas QLD 4814 AustraliaF. Francis, Townsville Hospital Pathology Queensland 100 Angus Smith Drive Douglas QLD 4814 AustraliaR. Norton, Townsville Hospital Pathology Queensland 100 Angus Smith Drive Douglas QLD 4814 Australia Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126 (Source: Infection) Infection journals http://www.medworm.com/rss/comments.php?id=2986781 Wed, 11 Nov 2009 06:57:25 +0100 2986781 http://www.medworm.com/index.php?rid=2986780&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj28250v3x2u7446l%2F Conclusion  Change to single shot prophylaxis along with an ongoing antibiotic stewardship program resulted in a cut-back in total antibiotic use amounting to as much as 15%. It would therefore appear that targeting interventions aimed at reducing antibiotic prophylaxis in surgical ICUs may be very worthwhile. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-009-9115-2Authors E. Meyer, Charité University Medicine Institute of Hygiene and Environmental Medicine Hindenburgdamm 27 12203 Berlin GermanyF. Schwab, Charité University Medicine Institute of Hygiene and Environmental Medicine Hindenburgdamm 27 12203 Berlin GermanyA. Pollitt, Klinikum Stuttgart, Katharinenhospital Institute of Hospital Hygiene Stuttgart GermanyW. Bettolo... Infection journals http://www.medworm.com/rss/comments.php?id=2986780 Wed, 11 Nov 2009 06:57:25 +0100 2986780 http://www.medworm.com/index.php?rid=2986784&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F13g2p355mqv31964%2F We describe the first reported case of bacterial pyomyositis of the right thigh caused by Streptococcus anginosus (S. milleri group) in an HIV-infected patient. The clinical presentation was complicated by multiple ring-enhancing lesions detected on magnetic resonance imaging of the brain. Evaluation for central nervous system toxoplasmosis, syphilis, and cryptococcal infection was negative. Aggressive antibiotic therapy directed against S. anginosus and surgical debridement were limb salvaging. Clinicians should consider S. anginosus as a causative pathogen in HIV-associated pyomyositis, particularly in complex presentations. Prompt surgical drainage may minimize complications due to S. anginosus, a pathogen associated with significant sequelae due to its invasive nature. Content Ty... Infection journals http://www.medworm.com/rss/comments.php?id=2986784 Wed, 11 Nov 2009 06:57:24 +0100 2986784 http://www.medworm.com/index.php?rid=2986783&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F15728r037845h703%2F We report on a 20-year-old woman with abdominal tuberculosis. Standard microbiological examination of ascites showed no acid-fast bacilli (AFB), and analysis for the Mycobacterium tuberculosis (MTB)-complex DNA by PCR was negative. However, the interferon-γ release assay (IGRA) of the ascites was positive after specific stimulation with mycobacterial antigens (ESAT-6/CFP-10/TB7.7[p4]), indicating an infection with MTB. The diagnosis of tuberculosis was later confirmed by histology, MTB culture, and PCR analysis of MTB-complex DNA in tissue samples taken during laparoscopy. Thus, the IGRA of ascites may guide the decision to start active treatment for tuberculosis. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s15010-009-9469-5Authors R. Lorenz, University Hospital U... Infection journals http://www.medworm.com/rss/comments.php?id=2986783 Wed, 11 Nov 2009 06:57:24 +0100 2986783 http://www.medworm.com/index.php?rid=3090879&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fjr88672650552t54%2F Conclusion:   Despite extensive pre-treatment and multiple resistances against prescribed HAART, our patients demonstrated a decline in viral load and a stable CD4-cell count over the observation period. We conclude that the activity of antiretroviral regimens is not exclusively explained by the current algorithms used for estimating antiretroviral drug activity. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-009-9022-6Authors T. Lorenzen, Hospital St. George Ifi–Institute for Interdisciplinary Medicine Lohmuehlenstrasse 5 20099 Hamburg GermanyI. Walther, Hospital St. George Ifi–Institute for Interdisciplinary Medicine Lohmuehlenstrasse 5 20099 Hamburg GermanyA. Stoehr, Hospital St. George Ifi–Institute for Interdiscipl... Infection journals http://www.medworm.com/rss/comments.php?id=3090879 Wed, 14 Oct 2009 05:57:22 +0100 3090879 http://www.medworm.com/index.php?rid=2896499&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fjr88672650552t54%2F Conclusion  Despite extensive pre-treatment and multiple resistances against prescribed HAART, our patients demonstrated a decline in viral load and a stable CD4-cell count over the observation period. We conclude that the activity of antiretroviral regimens is not exclusively explained by the current algorithms used for estimating antiretroviral drug activity. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-009-9022-6Authors T. Lorenzen, Hospital St. George Ifi–Institute for Interdisciplinary Medicine Lohmuehlenstrasse 5 20099 Hamburg GermanyI. Walther, Hospital St. George Ifi–Institute for Interdisciplinary Medicine Lohmuehlenstrasse 5 20099 Hamburg GermanyA. Stoehr, Hospital St. George Ifi–Institute for Interdisciplina... Infection journals http://www.medworm.com/rss/comments.php?id=2896499 Wed, 14 Oct 2009 05:57:22 +0100 2896499 http://www.medworm.com/index.php?rid=2896498&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fjh6037wx1719vx03%2F Conclusion  We observed unique features of persistent neuropsychiatric symptoms and lymphadenopathy 5 months after tularemia infection which were associated with delayed diagnosis and the lack of prompt response to therapy. This outbreak of oropharyngeal tularemia emphasizes the importance of a rapid diagnostic and investigative response to tularemia. This type of response can prevent ongoing exposure, as well as provide expeditious treatment to mitigate persistent symptoms. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-009-8193-5Authors N. Chitadze, National Center for Disease Control and Public Health Tbilisi GeorgiaT. Kuchuloria, Technology Management Company Tbilisi GeorgiaD. V. Clark, Walter Reed Army Institute of ... Infection journals http://www.medworm.com/rss/comments.php?id=2896498 Wed, 14 Oct 2009 05:57:22 +0100 2896498 http://www.medworm.com/index.php?rid=2896500&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2j425115m471761w%2F Conclusions  Based on the results of this meta-analysis, it would appear that an algorithm based on serial PCT measurements would allow a more judicious use of antibiotics than currently occurs during the traditional treatment of patients with infections. PCT-guided antibiotic treatment appears to be safe and may also improve clinical outcome. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-009-9034-2Authors H. Tang, Zhejiang University Intensive Care Unit, The Second Affiliated Hospital, School of Medicine Jiefang Road #88 310009 Hangzhou Zhejiang People’s Republic of ChinaT. Huang, Zhejiang University Intensive Care Unit, The Second Affiliated Hospital, School of Medicine Jiefang Road #88 310009 Hangzhou Zhejiang People’s... Infection journals http://www.medworm.com/rss/comments.php?id=2896500 Wed, 14 Oct 2009 05:57:21 +0100 2896500 http://www.medworm.com/index.php?rid=2816543&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ffm0474mx71330h46%2F Content Type Journal ArticleCategory EditorialDOI 10.1007/s15010-009-3509-zAuthors H. W. Doerr, Johann Wolfgang Goethe University Clinic Medical Institute for Virology Paul-Ehrlich-Str. 40 60596 Frankfurt/Main GermanyR. Allwinn, Johann Wolfgang Goethe University Clinic Medical Institute for Virology Paul-Ehrlich-Str. 40 60596 Frankfurt/Main GermanyJ. Cinatl, Johann Wolfgang Goethe University Clinic Medical Institute for Virology Paul-Ehrlich-Str. 40 60596 Frankfurt/Main Germany Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126 (Source: Infection) Infection journals http://www.medworm.com/rss/comments.php?id=2816543 Sat, 19 Sep 2009 05:51:52 +0100 2816543 http://www.medworm.com/index.php?rid=2810966&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx07l7120q31k6013%2F Content Type Journal ArticleCategory CorrespondenceDOI 10.1007/s15010-009-9003-9Authors A. F. Martins, Universidade Federal do Rio Grande do Sul, Coordenadoria de Vigilância em Saúde de Porto Alegre Medical Sciences Post-Graduate Program 372/3 Padre Cacique Avenue Porto Alegre RS 90000-000 BrazilR. Kuchenbecker, Hospital de Clínicas de Porto Alegre Hospital Infection Control Committee Porto Alegre BrazilT. Sukiennik, Complexo HospitalarSanta Casa Hospital Infection Control Committee Porto Alegre BrazilR. Boff, Centro Universitário IPA Metodista Porto Alegre BrazilK. C. Reiter, Universidade Federal do Rio Grande do Sul Medical Sciences Post-Graduate Program Porto Alegre BrazilL. Lutz, Universidade Federal do Rio Grande do Sul Medical Sciences Post-Graduate Program Porto Alegre Brazi... Infection journals http://www.medworm.com/rss/comments.php?id=2810966 Fri, 18 Sep 2009 16:10:30 +0100 2810966 http://www.medworm.com/index.php?rid=2810967&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm485t0r44522m715%2F Conclusions  The change in general influenza vaccination coverage in the 2007/2008 season compared to the previous season was small, but decreases were seen in some target groups. The underlying motivations for and against vaccination did not substantially change. An effort to activate those driving forces that would encourage vaccination as well as dealing with barriers that tend to prevent it may help enhance coverage rates in Europe in the future. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-009-8467-yAuthors P. R. Blank, University of Zurich Institute of Social and Preventive Medicine Hirschengraben 84 8001 Zurich SwitzerlandM. Schwenkglenks, University of Basel European Center of Pharmaceutical Medicine Blumenrain Base... Infection journals http://www.medworm.com/rss/comments.php?id=2810967 Fri, 18 Sep 2009 16:10:25 +0100 2810967 http://www.medworm.com/index.php?rid=2892363&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc3322417238138l2%2F Abstract   In April 2009, a novel H1N1 influenza A virus, the so-called pandemic H1N1/09 virus (former designations include swine influenza, novel influenza, swine-origin influenza A [H1N1] virus [S-OIV], Mexican flu, North American Flu) was identified in Mexico. The virus has since spread throughout the world and caused an influenza pandemic as defined by the criteria of the World Health Organization. This represents the first influenza A virus pandemic since the emergence of H3N2 (‘‘Hong Kong’’ Flu) in 1968. Vaccine production has started, and vaccines are expected to become available during the course of 2009. Although the pandemic H1N1/09 virus originates from the triple-reassortant swine influenza (H1) virus circulating in North American pigs, it is not epidem... Infection journals http://www.medworm.com/rss/comments.php?id=2892363 Fri, 18 Sep 2009 16:10:22 +0100 2892363 http://www.medworm.com/index.php?rid=2810969&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc622602821776232%2F Conclusions  Treatment with sequential iv/po moxifloxacin monotherapy once daily is clinically comparable to that with iv/po amoxicillin/clavulanate three times daily in the management of cSSSIs. Moxifloxacin’s simple dose regimen offers an advantage over amoxicillin/clavulanate and represents a valuable addition to current antibiotic regimens used in the treatment of cSSSIs. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-009-8468-xAuthors R. Vick-Fragoso, Hospital General “Dr Manuel Gea González” Infectious Disease Dept. Calzada de Tlalpan Tlalpan, Mexico, D.F. MexicoG. Hernández-Oliva, Centro Médico Nacional “La Raza”/Bayer de México Hospital de Infectología Mexico City MexicoJ. Cruz-Alcázar, Centro Médico N... Infection journals http://www.medworm.com/rss/comments.php?id=2810969 Fri, 18 Sep 2009 16:10:22 +0100 2810969 http://www.medworm.com/index.php?rid=2810968&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc3322417238138l2%2F Abstract  In April 2009, a novel H1N1 influenza A virus, the so-called pandemic H1N1/09 virus (former designations include swine influenza, novel influenza, swine-origin influenza A [H1N1] virus [S-OIV], Mexican flu, North American Flu) was identified in Mexico. The virus has since spread throughout the world and caused an influenza pandemic as defined by the criteria of the World Health Organization. This represents the first influenza A virus pandemic since the emergence of H3N2 (“Hong Kong” Flu) in 1968. Vaccine production has started, and vaccines are expected to become available during the course of 2009. Although the pandemic H1N1/09 virus originates from the triple-reassortant swine influenza (H1) virus circulating in North American pigs, it is not epidemic in pi... Infection journals http://www.medworm.com/rss/comments.php?id=2810968 Fri, 18 Sep 2009 16:10:22 +0100 2810968 http://www.medworm.com/index.php?rid=2810971&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F71u576117556246k%2F Conclusion  We conclude that tobramycin given in a daily single dose (with the advantage of being more practical in a home environment) has an efficacy equal to that of three daily doses in terms of elective antipseudomonal therapy in clinically stable patients with CF. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-009-8117-4Authors J. Riethmueller, University Children’s Hospital Hoppe-Seyler-Str. 1 72076 Tübingen GermanyM. Ballmann, University of Hannover Pediatric Dept. Hannover GermanyT. W. Schroeter, University Children′s Hospital Kiel Kiel GermanyP. Franke, University Children’s Hospital Hoppe-Seyler-Str. 1 72076 Tübingen GermanyR. von Butler, University Children’s Hospital Hoppe-Seyler-Str. 1 72076 Tübingen G... Infection journals http://www.medworm.com/rss/comments.php?id=2810971 Tue, 15 Sep 2009 22:02:26 +0100 2810971 http://www.medworm.com/index.php?rid=2810970&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F7825758740v76772%2F Abstract  A 78-year-old man with gastric diffuse large B cell lymphoma presented with persistent Helicobacter canis bacteremia while receiving chemotherapy. An examination of his medical history revealed a close exposure to dogs. The patient recovered after 4 weeks of antibiotic therapy. Immunocompromised persons who maintain close contacts with dogs may be at risk for this infection. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s15010-009-9067-6Authors D. Alon, Meir Medical Center Infectious Diseases Unit 59 Tshernichovski St 44281 Kfar Saba IsraelY. Ben-Nissan, Meir Medical Center The Microbiology Clinical Laboratory Kfar Saba IsraelY. Paitan, Meir Medical Center The Microbiology Clinical Laboratory Kfar Saba IsraelM. Chowers, Meir Medical Center Infe... Infection journals http://www.medworm.com/rss/comments.php?id=2810970 Tue, 15 Sep 2009 22:02:26 +0100 2810970 http://www.medworm.com/index.php?rid=2810972&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe0k61m632n269k04%2F Conclusion  We conclude that continuous or thrice-daily dosing of intravenous ceftazidime, both combined with once-daily tobramycin, are equally effective application regimens for elective antipseudomonal therapy in clinically stable patients with CF. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-009-8116-5Authors J. Riethmueller, University Children’s Hospital Hoppe-Seyler-Str. 1 72076 Tübingen GermanyS. Junge, University of Hannover Pediatric Department Hannover GermanyT. W. Schroeter, University Children’s Hospital Kiel Kiel GermanyK. Kuemmerer, University of Freiburg Freiburg GermanyP. Franke, University Children’s Hospital Hoppe-Seyler-Str. 1 72076 Tübingen GermanyM. Ballmann, University of Hannover Pediatric Depa... Infection journals http://www.medworm.com/rss/comments.php?id=2810972 Tue, 15 Sep 2009 22:02:25 +0100 2810972 http://www.medworm.com/index.php?rid=2810974&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm3344u248748rvx3%2F Abstract  Invasive aspergillosis is a major cause of morbidity and mortality in immunocompromised patients receiving intensive care. The double-sandwich ELISA for galactomannan is reported to have a high sensitivity (96.5%) for the detection of invasive aspergillosis when a cut-off value of 0.8 ng/ml is used. However, we have experienced a case of lethal disseminated aspergillosis in a patient that presented with a negative galactomannan (GM) test and persistent elevation of β-d glucan (BG) levels. A 63-year-old female was admitted to our Intensive Care Unit (ICU) in acute respiratory failure and elevated BG. She had been receiving medication for Goodpasture syndrome based on anti-glomerular basement membrane antibodies and myeloperoxidase–antineutrophil cytoplasmic ... Infection journals http://www.medworm.com/rss/comments.php?id=2810974 Tue, 15 Sep 2009 22:02:24 +0100 2810974 http://www.medworm.com/index.php?rid=2810973&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw74642t283425151%2F We report here a case of M. wisconsensis infection in a 46-year-old cirrhotic patient with acute cholecystitis. This is the first reported case of a M. wisconsensis infection in Belgium and the first reported case of human bacteremia caused by this bacterium. Our case report is followed by a review of the literature. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s15010-009-8446-3Authors A. Cardentey-Reyes, Université Libre de Bruxelles–Erasme Hospital Dept. of Microbiology Route de Lennik, 808 1070 Brussels BelgiumF. Jacobs, Université Libre de Bruxelles–Erasme Hospital Dept. of Infectious Diseases Brussels BelgiumM. J. Struelens, Université Libre de Bruxelles–Erasme Hospital Dept. of Microbiology Route de Lennik, 808 1070 Brussels BelgiumH. Rodriguez-Villalobo... Infection journals http://www.medworm.com/rss/comments.php?id=2810973 Tue, 15 Sep 2009 22:02:24 +0100 2810973 http://www.medworm.com/index.php?rid=2810975&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv7w64gh4x76m4172%2F Conclusion  Although 92.5% of our HIV-infected patients presented a NNIS score ≤ 1, the SSI rate was twofold higher than that reported in Italian and European studies for the general population, with more severe clinical presentations. This is the first report of an association between HCV–HIV co-infection and SSI occurrence. Additionally, the viro-immunological status of our patients was not related to SSI occurrence, which suggests the need for further research for other potential risk factors that may be implicated in the occurrence of SSI. Content Type Journal ArticleCategory Brief ReportDOI 10.1007/s15010-009-8225-1Authors C. M. J. Drapeau, National Institute for Infectious Diseases “L. Spallanzani” 2nd Infectious Diseases Division Via Portuense 292 0014... Infection journals http://www.medworm.com/rss/comments.php?id=2810975 Tue, 15 Sep 2009 22:02:23 +0100 2810975 http://www.medworm.com/index.php?rid=2686225&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg18176h24p774q26%2F We describe the first case of CGD with femoral osteomyelitis due to Cladophialophora arxii, which is a member of the dematiaceous group. The causative fungus was identified on the basis of its morphological characteristics, growth temperature profile, and nucleotide sequence on the internal transcribed space region of the ribosomal gene. The patient was successfully treated with surgical debridement, subsequent administration of itraconazolem and interferon-γ. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s15010-009-8238-9Authors T. Shigemura, Shinshu University School of Medicine Dept. of Pediatrics 3-1-1 Asahi Matsumoto, Nagano 390-8621 JapanK. Agematsu, Shinshu University School of Medicine Dept. of Pediatrics 3-1-1 Asahi Matsumoto, Nagano 390-8621 JapanT. Yamazak... Infection journals http://www.medworm.com/rss/comments.php?id=2686225 Sun, 09 Aug 2009 07:16:14 +0100 2686225 http://www.medworm.com/index.php?rid=2686227&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp784rt3847753np3%2F Conclusion  The detection of ESAT-6 in the CSF of TBM patients by indirect ELISA is a promising method and can be used to develop an immunodiagnostic assay with increased sensitivity and specificity. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-009-8261-xAuthors R. S. Kashyap, Central India Institute of Medical Sciences Biochemistry Research Laboratory Nagpur 440010 IndiaS. S. Ramteke, Central India Institute of Medical Sciences Biochemistry Research Laboratory Nagpur 440010 IndiaS. H. Morey, Central India Institute of Medical Sciences Biochemistry Research Laboratory Nagpur 440010 IndiaH. J. Purohit, National Environmental Engineering Research Institute Environmental Genomics Unit Nehru Marg Nagpur IndiaG. M. Taori, Central ... Infection journals http://www.medworm.com/rss/comments.php?id=2686227 Sun, 09 Aug 2009 07:16:12 +0100 2686227 http://www.medworm.com/index.php?rid=2686226&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff416q72q1qku830h%2F Conclusions  While PCR is the most sensitive assay for the diagnosis of influenza, the RCA can still be used for diagnosis and surveillance of this disease. Based on our findings and given the known fact that influenza antibodies reach a plateau 2–4 weeks after immunization, the optimal time for vaccination in Germany is from October through November. Kindergarten and school-aged children represent an important reservoir of infection. Consequently, routine immunization should be considered for this age group to prevent the spread of influenza. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-009-8434-7Authors E. Terletskaia-Ladwig, Labor Prof. Gisela Enders und Partner und Institut für Virologie, Infektiologie und Epid... Infection journals http://www.medworm.com/rss/comments.php?id=2686226 Sun, 09 Aug 2009 07:16:12 +0100 2686226 http://www.medworm.com/index.php?rid=2686228&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F7h0312327062w47u%2F Conclusion  Invasive VREF infection during this outbreak was confined to patients with severe underlying comorbidity. The mortality of VREF infection remained high, despite treatment with newer VREF-active antibiotics such as linezolid and quinupristin–dalfopristin. Content Type Journal ArticleCategory Brief ReportDOI 10.1007/s15010-009-9023-5Authors C. Theilacker, University Hospital Center for Infectious Diseases and Travel Medicine, Dept. of Medicine Hugstetter Strasse 55 79106 Freiburg GermanyD. Jonas, University Hospital Institute for Environmental Health Sciences Freiburg GermanyJ. Huebner, University Hospital Center for Infectious Diseases and Travel Medicine, Dept. of Medicine Hugstetter Strasse 55 79106 Freiburg GermanyH. Bertz, University Hospital Dept. of H... Infection journals http://www.medworm.com/rss/comments.php?id=2686228 Sun, 09 Aug 2009 07:16:11 +0100 2686228 http://www.medworm.com/index.php?rid=2686230&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F6500m121839t8mmj%2F Abstract  Cutaneous vasculitis is a clinical entity with a broad differential diagnosis, including an adverse drug reaction. It is defined as inflammation of skin blood vessel walls. During a 7-year-period, we observed three patients who developed isolated cutaneous vasculitis during antibiotic therapy of bacterial infection. All were treated with a fluoroquinolone (ciprofloxacin or levofloxacin) combined with rifampin (two cases) or flucloxacillin (three cases), respectively. In all three cases the lesions gradually resolved after treatment with the inciting fluoroquinolone had been stopped. In one patient, leukocytoclastic small-vessel vasculitis was histologically confirmed. Fluoroquinolone-associated cutaneous vasculitis consists of an isolated self-limiting disorder th... Infection journals http://www.medworm.com/rss/comments.php?id=2686230 Sun, 09 Aug 2009 07:16:10 +0100 2686230 http://www.medworm.com/index.php?rid=2686229&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe423040673q4t801%2F Conclusion  The composition of the intra-abdominal flora found in critically ill patients with abdominal sepsis varies depending on the location of the perforation. The efficacy of combined surgical and antibiotic treatment was 87% in 4 weeks for AGNB. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-009-8249-6Authors J. de Ruiter, University Medical Center Groningen Dept. of Anesthesiology Groningen The NetherlandsJ. Weel, Streeklaboratorium Friesland Dept. of Medical Microbiology Leeuwarden The NetherlandsE. Manusama, Medical Center Leeuwarden Dept. of Surgery Leeuwarden The NetherlandsW. P. Kingma, Medical Center Leeuwarden Dept. of Intensive Care Leeuwarden The NetherlandsP. H. J. van der Voort, Onze Lieve Vrouwe Gasthui... Infection journals http://www.medworm.com/rss/comments.php?id=2686229 Sun, 09 Aug 2009 07:16:10 +0100 2686229 http://www.medworm.com/index.php?rid=2686231&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd572gj01547t7365%2F Conclusion  The virological response to ABC + TDF-containing regimens in this moderately-to-heavily treatment-experienced cohort was good. Higher viral load and the presence of M41L at baseline were associated with worse virological responses, while the concomitant prescription of drugs enhancing the genetic barrier of the regimen conveyed a reduced risk of virological failure. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-009-8237-xAuthors S. Di Giambenedetto, Catholic University Institute of Clinical Infectious Diseases Largo Gemelli 8 00168 Rome ItalyC. Torti, University of Brescia Brescia ItalyM. Prosperi, Roma Tre University Rome ItalyN. Manca, University of Brescia Brescia ItalyG. Lapadula, University of Bresc... Infection journals http://www.medworm.com/rss/comments.php?id=2686231 Sun, 09 Aug 2009 07:16:08 +0100 2686231 http://www.medworm.com/index.php?rid=2686232&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F54t324222746484w%2F Conclusions  In relation to the high prevalence of occult HBV infection, particularly in HIV/HCV-coinfected individuals, it is necessary to clarify the clinical impact of this cryptic infection by monitoring HBV-DNA in plasma using the correct approach. Similarly to HBsAg-positive individuals of the Mediterranean area, HBV genotype D is invariably detected in this cohort of HIV-infected patients with occult HBV infection. Content Type Journal ArticleCategory Brief ReportDOI 10.1007/s15010-008-8194-9Authors G. Morsica, S. Raffaele Scientific Institute Dept. of Infectious Diseases Via Stamira d’Ancona, 20 20127 Milan ItalyF. Ancarani, University of Ancona Institute of Infectious Diseases and Public Health Ancona ItalyS. Bagaglio, S. Raffaele Scientific Institute Dept.... Infection journals http://www.medworm.com/rss/comments.php?id=2686232 Sun, 09 Aug 2009 07:16:07 +0100 2686232 http://www.medworm.com/index.php?rid=2651732&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu02p775068398u3p%2F Conclusion  These results could be used as a tool to create goal-specific strategies for motivating hand hygiene amongst nurses and physicians in Hong Kong, with appropriate promotional interventions delivered to the different professional groups and specialties. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-009-8245-xAuthors J. W. M. Tai, Queen Mary Hospital Infection Control Unit Pokfulam Road Hong Kong Special Administrative Region of ChinaE. S. B. Mok, The Hong Kong Polytechnic University School of Nursing Kowloon, Hong Kong Special Administrative Region of ChinaP. T. Y. Ching, Queen Mary Hospital Infection Control Unit Pokfulam Road Hong Kong Special Administrative Region of ChinaW. H. Seto, University of Hong Kong Dept. ... Infection journals http://www.medworm.com/rss/comments.php?id=2651732 Mon, 27 Jul 2009 22:53:04 +0100 2651732 http://www.medworm.com/index.php?rid=2651733&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk21163k05112vl43%2F Conclusions  Episodes of HCV-related acute liver cell necrosis after AHC may be associated to different virological patterns, such as the establishment of a chronic HCV infection, a reactivation of an occult virus, or a reinfection by a different HCV genotype. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-008-8197-6Authors E. Sagnelli, Second University of Naples Dept. of Public Medicine, Section of Infectious Diseases c/o Ospedale Gesù e Maria, Via D. Cotugno 1 80135 Naples ItalyC. Argentini, Istituto Superiore di Sanità Dept. of Infectious, Parasitic and Immunomediated Diseases, Viral Hepatitis Unit Rome ItalyD. Genovese, Istituto Superiore di Sanità Dept. of Infectious, Parasitic and Immunomediated Diseases, Viral Hepa... Infection journals http://www.medworm.com/rss/comments.php?id=2651733 Mon, 27 Jul 2009 22:52:58 +0100 2651733 http://www.medworm.com/index.php?rid=2642992&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw371624m3877242q%2F Conclusion  Our data, while confirming the effectiveness of anti hepatitis B vaccination, highlight the need for post-vaccination follow-up, particularly in high-risk categories, to prolong protection, through booster doses if necessary. We show, moreover, the importance of maintaining active surveillance in the territory to improve follow-up to chronic carriers and to sensitize families. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-008-8252-3Authors L. Bracciale, Siena University Infectious Diseases Clinic, Dept. of Molecular Biology Siena ItalyM. Fabbiani, Siena University Infectious Diseases Clinic, Dept. of Molecular Biology Siena ItalyA. Sansoni, Siena University Infectious Diseases Clinic, Dept. of Molecular Biology Si... Infection journals http://www.medworm.com/rss/comments.php?id=2642992 Sat, 25 Jul 2009 08:41:45 +0100 2642992 http://www.medworm.com/index.php?rid=2642991&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F60781l2t7l6q2374%2F Content Type Journal ArticleCategory EditorialDOI 10.1007/s15010-009-3409-2Authors C. Ruef Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126 (Source: Infection) Infection journals http://www.medworm.com/rss/comments.php?id=2642991 Sat, 25 Jul 2009 08:41:45 +0100 2642991 http://www.medworm.com/index.php?rid=2642993&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm274jx8142p7v321%2F Abstract  Since the origin of an “International Collaborative Study on Antibiotic Sensitivity Testing” in 1971, considerable advancement has been made to standardize clinical susceptibility testing procedures of antimicrobial agents. However, a consensus on the methods to be used and interpretive criteria was not reached, so the results of susceptibility testing were discrepant. Recently, the European Committee on Antimicrobial Susceptibility Testing achieved a harmonization of existing methods for susceptibility testing and now co-ordinates the process for setting breakpoints. Previously, breakpoints were set by adjusting the mean pharmacokinetic parameters derived from healthy volunteers to the susceptibilities of a population of potential pathogens expressed as the... Infection journals http://www.medworm.com/rss/comments.php?id=2642993 Sat, 25 Jul 2009 08:41:44 +0100 2642993 http://www.medworm.com/index.php?rid=2642995&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl410141x7p731861%2F Conclusion  The rate of IA found in this investigation is within the range reported in published studies. Based on our data, extended antifungal prophylaxis should be given to liver transplant patients with specific risk factors, such as renal insufficiency, requirement for dialysis, CMV infection, or thrombocytopenia. Additional focus should be on the prevention of CMV infections. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-008-8124-xAuthors M. Rosenhagen, University Hospital of Heidelberg Pharmacy Dept. INF 670 69120 Heidelberg GermanyR. Feldhues, University Hospital of Heidelberg Institute of Hygiene Heidelberg GermanyJ. Schmidt, University Hospital of Heidelberg Dept. of General, Visceral and Transplantation Surgery Hei... Infection journals http://www.medworm.com/rss/comments.php?id=2642995 Sat, 25 Jul 2009 08:41:43 +0100 2642995 http://www.medworm.com/index.php?rid=2642994&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv172361r8x0348h1%2F Conclusions  The diagnosis of CABP can be difficult in cirrhotic HIV-positive patients because clinical presentation is milder. However, CABP needs to be promptly recognized because mortality is higher in these patients. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-009-8140-5Authors D. Manno, University of Brescia Dept. of Infectious and Tropical Diseases P.zzle Spedali Civili 1 25123 Brescia ItalyM. Puoti, University of Brescia Dept. of Infectious and Tropical Diseases P.zzle Spedali Civili 1 25123 Brescia ItalyL. Signorini, University of Brescia Dept. of Infectious and Tropical Diseases P.zzle Spedali Civili 1 25123 Brescia ItalyG. Lapadula, University of Brescia Dept. of Infectious and Tropical Diseases P.zzle Spedali Civi... Infection journals http://www.medworm.com/rss/comments.php?id=2642994 Sat, 25 Jul 2009 08:41:43 +0100 2642994 http://www.medworm.com/index.php?rid=2642996&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F4444390812217u71%2F Content Type Journal ArticleCategory CorrespondenceDOI 10.1007/s15010-009-9016-4Authors J. E. Nolte, Sheba Medical Center Dept. of Medicine B Tel-Hashomer 52621 IsraelA. Altman, Sheba Medical Center Dept. of Medicine B Tel-Hashomer 52621 IsraelM. Szyper-Kravitz, Sheba Medical Center Dept. of Medicine B Tel-Hashomer 52621 IsraelY. Shoenfeld, Sheba Medical Center Dept. of Medicine B Tel-Hashomer 52621 IsraelE. Zimlichman, Sheba Medical Center Dept. of Medicine B Tel-Hashomer 52621 Israel Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126 (Source: Infection) Infection journals http://www.medworm.com/rss/comments.php?id=2642996 Sat, 25 Jul 2009 08:41:42 +0100 2642996 http://www.medworm.com/index.php?rid=2642997&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk58343lt18613688%2F Conclusion  Fournier’s gangrene remains a major challenge with a high mortality. Our results suggest that women are more commonly affected than has generally been assumed. Contrary to published reports, we found that anorectal sources appear to account for more cases of Fournier’s gangrene than urological sources. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-008-8169-xAuthors R. Czymek, University of Lübeck Medical School Department of Surgery Ratzeburger Allee 160 23538 Lübeck GermanyP. Hildebrand, University of Lübeck Medical School Department of Surgery Ratzeburger Allee 160 23538 Lübeck GermanyM. Kleemann, University of Lübeck Medical School Department of Surgery Ratzeburger Allee 160 23538 Lübeck GermanyU. Rob... Infection journals http://www.medworm.com/rss/comments.php?id=2642997 Sat, 25 Jul 2009 08:41:39 +0100 2642997 http://www.medworm.com/index.php?rid=2460308&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F225961w455x24303%2F Conclusions  Colistin is a safe option for the treatment of MDRP infections, with acceptable clinical outcomes. However, bacteriological eradication is difficult to achieve, especially in COPD patients. Content Type Journal ArticleCategory Brief ReportDOI 10.1007/s15010-009-8342-xAuthors M. Montero, Autonomous University of Barcelona Dept. of Internal Medicine and Infectious Diseases, Hospital del Mar Paseo Marítimo 25-29 08003 Barcelona SpainJ. P. Horcajada, Autonomous University of Barcelona Dept. of Internal Medicine and Infectious Diseases, Hospital del Mar Paseo Marítimo 25-29 08003 Barcelona SpainL. Sorlí, Autonomous University of Barcelona Dept. of Internal Medicine and Infectious Diseases, Hospital del Mar Paseo Marítimo 25-29 08003 Barcelona SpainF. Alvarez... Infection journals http://www.medworm.com/rss/comments.php?id=2460308 Fri, 05 Jun 2009 08:58:09 +0100 2460308 http://www.medworm.com/index.php?rid=2460307&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fal1j81jx57830125%2F Conclusion  At the level of individual medical specialties within one hospital, a higher prevalence of antimicrobial use among patients was associated with a significantly higher observed antimicrobial resistance. The use of CIP was associated with a stronger increase in resistance than the use of beta-lactams. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-009-8325-yAuthors I. Willemsen, Amphia Hospital Laboratory for Microbiology and Infection Control PO Box 90158 4800 RK Breda The NetherlandsD. Bogaers-Hofman, Amphia Hospital Laboratory for Microbiology and Infection Control PO Box 90158 4800 RK Breda The NetherlandsM. Winters, Amphia hospital Dept. of Pharmacy Breda The NetherlandsJ. Kluytmans, Amphia Hospital Laboratory f... Infection journals http://www.medworm.com/rss/comments.php?id=2460307 Fri, 05 Jun 2009 08:58:09 +0100 2460307 http://www.medworm.com/index.php?rid=2460309&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F93107440l0365u71%2F We report a case of a patient with a history of chemotherapy for non-Hodgkin lymphoma who developed pain and progressive paresthesia of the right arm 6 weeks after remission. Relapsing lymphoma was suspected, and steroid and radiation treatment were initiated, but the patient died 5 days later due to multiple organ failure. Autopsy revealed disseminated toxoplasmosis. This case illustrates that toxoplasmosis should be suspected in patients with neoplastic disease, especially lymphomas, who present with unexplained neurologic, pulmonary, or febrile symptoms during or after chemotherapy. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s15010-009-9007-5Authors M. A. Herold, University Hospital of Zurich Division of Infectious Diseases and Hospital Epidemiology Rämis... Infection journals http://www.medworm.com/rss/comments.php?id=2460309 Fri, 05 Jun 2009 08:58:07 +0100 2460309 http://www.medworm.com/index.php?rid=2460310&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F132253814j7p45x7%2F Content Type Journal ArticleCategory CorrespondenceDOI 10.1007/s15010-009-8373-3Authors W.-T. Huang, Zuoying Armed Forces General Hospital Dept. of Medicine Kaohsiung Taiwan, ROCY.-J. Hsu, National Defense Medical Center Division of Nephrology, Dept. of Medicine, Tri-Service General Hospital Number 325, Section 2, Cheng-Kung Road Neihu 114, Taipei Taiwan, ROCP.-L. Chu, National Defense Medical Center Division of Nephrology, Dept. of Medicine, Tri-Service General Hospital Number 325, Section 2, Cheng-Kung Road Neihu 114, Taipei Taiwan, ROCS.-H. Lin, National Defense Medical Center Division of Nephrology, Dept. of Medicine, Tri-Service General Hospital Number 325, Section 2, Cheng-Kung Road Neihu 114, Taipei Taiwan, ROC Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126... Infection journals http://www.medworm.com/rss/comments.php?id=2460310 Fri, 05 Jun 2009 08:58:06 +0100 2460310 http://www.medworm.com/index.php?rid=2449957&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa48773h36562681m%2F Conclusions  The principals of antiretroviral treatment in asymptomatic naïve patients with advanced HIV infection are the same as those applicable to the general population with asymptomatic HIV infection. Naïve patients with advanced HIV infection and a history of AIDS-defining illnesses urgently need antiretroviral treatment, with the choice of antiretroviral regimen and timetable based on such factors as concomitant treatment and prophylaxis, drug interactions, and potential concomitant drug toxicity. Finally, an adequate counseling program – both before and after HIV-testing – that includes aspects other than treatment adherence monitoring is a crucial step in disease management. Content Type Journal ArticleCategory Consensus ReportDOI 10.1007/s15010-008-81... Infection journals http://www.medworm.com/rss/comments.php?id=2449957 Fri, 29 May 2009 06:58:14 +0100 2449957 http://www.medworm.com/index.php?rid=2449956&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj64552p3223n3001%2F Content Type Journal ArticleCategory EditorialDOI 10.1007/s15010-009-3309-5Authors C. Ruef Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126 (Source: Infection) Infection journals http://www.medworm.com/rss/comments.php?id=2449956 Fri, 29 May 2009 06:58:14 +0100 2449956 http://www.medworm.com/index.php?rid=2444215&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F01758645142g6157%2F Conclusions  Unboosted ATV treatment did not worsen liver disease and was able to maintain or gain immuno-virological eligibility for OLTx in all patients, with a limited effect on unconjugated bilirubin. These results suggest that ATV is an easy-to-use drug in patients with ESLD. Content Type Journal ArticleCategory Brief ReportDOI 10.1007/s15010-008-8025-zAuthors G. Guaraldi, University of Modena and Reggio Emilia Dept. of Internal Medicine and Medical Specialties, Clinic of Infectious Diseases Via del Pozzo 71 41100 Modena ItalyS. Cocchi, University of Modena and Reggio Emilia Dept. of Internal Medicine and Medical Specialties, Clinic of Infectious Diseases Via del Pozzo 71 41100 Modena ItalyA. Motta, University of Modena and Reggio Emilia Dept. of Internal Medicine ... Infection journals http://www.medworm.com/rss/comments.php?id=2444215 Wed, 27 May 2009 06:10:28 +0100 2444215 http://www.medworm.com/index.php?rid=2444214&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F880245655hpk7483%2F Conclusions  Influenza complications place a large burden on healthcare providers and society. Neuraminidase inhibitors can reduce the incidence of such complications, particularly in high-risk groups. Content Type Journal ArticleCategory ReviewDOI 10.1007/s15010-009-8241-1Authors B. R. Ruf, Klinikum Sankt Georg Leipzig 2nd Dept. of Internal Medicine, Division of Infectious Diseases and Tropical Medicine Leipzig GermanyT. Szucs, University of Zurich Institute of Social and Preventive Medicine Zurich Switzerland Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126 (Source: Infection) Infection journals http://www.medworm.com/rss/comments.php?id=2444214 Wed, 27 May 2009 06:10:28 +0100 2444214 http://www.medworm.com/index.php?rid=2444216&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ffk46m4hm02126135%2F Conclusions  Hyperbilrubinemia is a common side effect of an ATV pharmacotherapeutic regimen. However, grade IV increase in bilirubin was rarely found. In most cases, ATV hyperbilirubinemia appeared to be an innocent phenomenon as far as the risk of a subsequent increase in liver enzyme level is concerned. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-008-8010-6Authors C. Torti, University of Brescia School of Medicine, Institute of Infectious and Tropical Diseases P.le Spedali Civili, 1 25123 Brescia ItalyG. Lapadula, University of Brescia School of Medicine, Institute of Infectious and Tropical Diseases P.le Spedali Civili, 1 25123 Brescia ItalyA. Antinori, National Institute of Infectious Diseases Rome ItalyT. Quirino, Osp... Infection journals http://www.medworm.com/rss/comments.php?id=2444216 Wed, 27 May 2009 06:10:26 +0100 2444216 http://www.medworm.com/index.php?rid=2392975&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff24w0231328p31l6%2F Conclusions:   In Switzerland, RSV infections lead to the IMC/ICU admission of approximately 1%–2% of each annual birth cohort. Although prematurity, BPD, and CHD are significant risk factors, non-pharmacological preventive strategies should not be restricted to these high-risk patients but also target young NT/FT infants since they constitute 77% of infants requiring IMC/ICU admission. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-008-8130-zAuthors T. M. Berger, Children’s Hospital of Lucerne Neonatal and Pediatric Intensive Care Unit Spitalstrasse 6000 Lucerne SwitzerlandC. Aebi, University of Bern, Inselspital Dept. of Pediatrics 3010 Bern SwitzerlandA. Duppenthaler, University of Bern, Inselspital Dept. of Pediatrics... Infection journals http://www.medworm.com/rss/comments.php?id=2392975 Sat, 02 May 2009 05:48:54 +0100 2392975 http://www.medworm.com/index.php?rid=2384205&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn3008n6v06860212%2F Conclusions  The PROGRESS international sepsis registry demonstrates that a large web-based sepsis registry is feasible. Wide variations in outcomes and use of sepsis therapies were observed between countries. These results also suggest that additional opportunities exist across countries to improve severe sepsis outcomes. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-008-8203-zAuthors R. Beale, Guy’s and St. Thomas’ NHS Foundation Trust, St. Thomas’ Hospital Adult Intensive Care Unit Lambeth Palace Road, London London SE1 7EH UKK. Reinhart, Friedrich Schiller University Dept. of Anesthesiology and Intensive Care Jena GermanyF. M. Brunkhorst, Friedrich Schiller University Dept. of Anesthesiology and Intensive Care Jena ... Infection journals http://www.medworm.com/rss/comments.php?id=2384205 Thu, 30 Apr 2009 05:57:52 +0100 2384205 http://www.medworm.com/index.php?rid=2367740&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv383000p467wt650%2F Content Type Journal ArticleCategory CorrespondenceDOI 10.1007/s15010-008-8246-1Authors F.H.R. De Man, Kantonsspital Clinic of Orthopaedic Surgery Liestal SwitzerlandP. Graber, Basel University Medical Clinic Liestal Unit of Infectious Diseases Rheinstrasse 26 4410 Liestal SwitzerlandM. Lüem, Kantonsspital Clinic of Orthopaedic Surgery Liestal SwitzerlandW. Zimmerli, Basel University Medical Clinic Liestal Unit of Infectious Diseases Rheinstrasse 26 4410 Liestal SwitzerlandP.E. Ochsner, Kantonsspital Clinic of Orthopaedic Surgery Liestal SwitzerlandP. Sendi, Basel University Medical Clinic Liestal Unit of Infectious Diseases Rheinstrasse 26 4410 Liestal Switzerland Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126 (Source: Infection) Infection journals http://www.medworm.com/rss/comments.php?id=2367740 Fri, 24 Apr 2009 07:05:21 +0100 2367740 http://www.medworm.com/index.php?rid=2367742&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F41m08601776h2504%2F This report describes a case of C. sordellii bacteremia in a patient with rectum carcinoma and liver metastases. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s15010-008-8192-yAuthors J. Matten, Cologne-Merheim Medical Center Dept. of Clinical Microbiology Ostmerheimerstr. 200 51109 Cologne GermanyV. Buechner, Cologne-Holweide Medical Centre Dept. of Anaesthesiology Cologne GermanyR. Schwarz, Cologne-Merheim Medical Center Dept. of Clinical Microbiology Ostmerheimerstr. 200 51109 Cologne Germany Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126 (Source: Infection) Infection journals http://www.medworm.com/rss/comments.php?id=2367742 Fri, 24 Apr 2009 07:05:18 +0100 2367742 http://www.medworm.com/index.php?rid=2367744&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj43063j6336559q6%2F Abstract  A 53-year old immunocompetent Swiss female is described who developed severe meningoencephalitis due to infection with Cryptococcus gattii 13 months following exposure on Vancouver Island, Canada. Diagnosis was based on cerebrospinal fluid (CSF) examination, i.e., positive India-ink staining, positive latex particle agglutination, and positive culture. Species identification was performed by growth on l-canavanine–glycine–bromthymol blue medium and by sequencing of the intergenic and internal transcribed spacer regions of the rRNA genes. After initial therapy with fluconazole by which the patient did not improve, therapy was changed to amphotericin B and flucytosine and later to high-dose fluconazole and amphotericin B. Despite long-term treatment and exter... Infection journals http://www.medworm.com/rss/comments.php?id=2367744 Fri, 24 Apr 2009 07:05:16 +0100 2367744 http://www.medworm.com/index.php?rid=2288698&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F6gx36685t614031m%2F Content Type Journal ArticleCategory EditorialDOI 10.1007/s15010-009-3209-8Authors C. Ruef Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126 (Source: Infection) Infection journals http://www.medworm.com/rss/comments.php?id=2288698 Tue, 24 Mar 2009 07:03:13 +0100 2288698 http://www.medworm.com/index.php?rid=2288699&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw325w3678357p4p6%2F Abstract Background  It has been traditionally postulated that individuals, once infected by Mycobacterium tuberculosis, will retain throughout their entire lifetime latent bacilli which will remain dormant in old lesions. This bacillus would then be the source of a later reactivation of active tuberculosis (TB), with the aid of resuscitation factors. Unfortunately, the presence of these bacilli can only be predicted by indirect immunological methods, such as the tuberculin skin test (TST) or T cell interferon–gamma release assays. Other evidence shows that a 9-month isoniazid treatment of TST+individuals converting to TB reduces the incidence of TB by approximately 90%. Questions  Taking into account this widely accepted framework, I suggest that there ar... Infection journals http://www.medworm.com/rss/comments.php?id=2288699 Tue, 24 Mar 2009 07:03:12 +0100 2288699 http://www.medworm.com/index.php?rid=2288700&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd0n08hqrwg234666%2F Abstract  A panel of leading Italian specialists in infectious diseases, obstetrics and gynaecology met in a national consensus workshop on women facing HIV to review critical aspects and discuss recommendations for selected key questions on four issues: (1) women and highly active antiretroviral therapy (HAART): access to care and adherence to therapy, side effects and drug–drug interaction; (2) HIV-infected pregnant women: prevention of mother to child transmission; (3) desire for children among women living with HIV: assisted reproduction; (4) sexually transmitted diseases and genital disturbances. The method of a nominal group meeting was used, and recommendations were graded for their strength and quality of evidence using a system based on the one adopted by the Inf... Infection journals http://www.medworm.com/rss/comments.php?id=2288700 Tue, 24 Mar 2009 07:03:11 +0100 2288700 http://www.medworm.com/index.php?rid=2491045&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu1017834231829n3%2F Abstract   In the absence of symptoms characteristic of tuberculosis (TB), a condition termed clinical latency, diagnosis is currently impossible by detection of the microorganism itself and resorts to the demonstration of an immunological memory response to antigens of Mycobacterium tuberculosis (Mtb). Whether latency is synonymous to chronic persistent infection with viable Mtb in all instances has been difficult to establish. The physical and physiological state of Mtb during latency is much disputed: are organisms mostly dormant, in a nonreplicating state of persistence, and characterized by lipid inclusions and metabolic adaptation to hypoxia, or do they continue to replicate and sometimes even escape from the fringes of granulomatous lesions or alveolar epithelial cel... Infection journals http://www.medworm.com/rss/comments.php?id=2491045 Tue, 24 Mar 2009 07:03:09 +0100 2491045 http://www.medworm.com/index.php?rid=2288702&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu1017834231829n3%2F Abstract  In the absence of symptoms characteristic of tuberculosis (TB), a condition termed clinical latency, diagnosis is currently impossible by detection of the microorganism itself and resorts to the demonstration of an immunological memory response to antigens of Mycobacterium tuberculosis (Mtb). Whether latency is synonymous to chronic persistent infection with viable Mtb in all instances has been difficult to establish. The physical and physiological state of Mtb during latency is much disputed: are organisms mostly dormant, in a non-replicating state of persistence, and characterized by lipid inclusions and metabolic adaptation to hypoxia, or do they continue to replicate and sometimes even escape from the fringes of granulomatous lesions or alveolar epithelial cell... Infection journals http://www.medworm.com/rss/comments.php?id=2288702 Tue, 24 Mar 2009 07:03:09 +0100 2288702 http://www.medworm.com/index.php?rid=2288701&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc25vlgr39327j2k3%2F Conclusions  Adherence to CDC SSI guidelines in Italy is fair. The evidence of the recommendation does not influence adherence. Organizational improvements, especially those regarding hair removal and the timing of antibiotic prophylaxis, should be implemented in most hospitals. Content Type Journal ArticleCategory Brief ReportDOI 10.1007/s15010-008-7474-8Authors A. Pan, Istituti Ospitalieri di Cremona Divisione di Malattie Infettive Viale Concordia 1 26100 Cremona ItalyL. Ambrosini, Università di Brescia Istituto di Anestesia e Rianimazione Spedali Civili 25123 Brescia ItalyA. Patroni, Ospedale di Esine Divisione di Medicina 25040 Esine BS ItalyL. Soavi, Università di Brescia Istituto di Malattie Infettive e Tropicali, Spedali Civili Brescia ItalyL. Signorini, Unive... Infection journals http://www.medworm.com/rss/comments.php?id=2288701 Tue, 24 Mar 2009 07:03:09 +0100 2288701 http://www.medworm.com/index.php?rid=2264390&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2lk17720x87hu3qq%2F Conclusion  We report one case of a S. aureus biofilm infection documented on a cochlear implant, as assessed by immuno-microscopy. The biofilm was likely responsible for the persistent infection which manifested for many months after the implant surgery and could explain the unusual bacterial phenotypic resistance against administered antimicrobial agents. Content Type Journal ArticleCategory Brief ReportDOI 10.1007/s15010-008-8335-1Authors M. I. Kos, Geneva University Hospitals Geneva Cochlear Implant Centre, Oto-Rhino-Laryngology, Head and Neck surgery, Service Geneva 4 SwitzerlandL. Stenz, Geneva University Hospital Genomic Research Laboratory, Infectious Diseases Service Geneva 4 SwitzerlandP. François, Geneva University Hospital Genomic Research Laboratory, Infe... Infection journals http://www.medworm.com/rss/comments.php?id=2264390 Thu, 12 Mar 2009 13:47:58 +0100 2264390 http://www.medworm.com/index.php?rid=2264392&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl0l6413827232274%2F Conclusion  The model estimated a higher clinical cure (+8.7%) and survival (+13.2%) for linezolid compared with vancomycin at an incremental cost of €420 per treatment episode. The cost–benefit profile suggests that linezolid could be considered a cost-effective alternative to vancomycin in the treatment of patients with NP caused by suspected MRSA in Germany. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-008-8046-7Authors E. De Cock, United BioSource Corporation Health Economics Carrer Torrent del Remei, 5-11, 4o-2a 08023 Barcelona SpainW. A. Krueger, Universitätsklinik Tübingen Klinik für Anästhesiologie und Intensivmedizin Tübingen GermanyS. Sorensen, United BioSource Corporation Bethesda USAT. Baker, Unite... Infection journals http://www.medworm.com/rss/comments.php?id=2264392 Wed, 11 Mar 2009 11:26:28 +0100 2264392 http://www.medworm.com/index.php?rid=2264391&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv0441p51n0310515%2F Conclusions  The use of DDDs as currently defined by WHO/ATC for measuring hospital antibiotic consumption may be associated with a substantial overestimation of antibiotic use density, while using practice guideline-derived RDDs may yield more valid antibiotic exposure estimates that would be helpful in cross-sectional and longitudinal analyses of antibiotic consumption. Content Type Journal ArticleCategory Brief ReportDOI 10.1007/s15010-008-8138-4Authors K. de With, University Hospital Dept. of Medicine, Center for Infectious Diseases and Travel Medicine Hugstetter Strasse 55 79106 Freiburg GermanyH. Bestehorn, University Hospital Dept. of Medicine, Center for Infectious Diseases and Travel Medicine Hugstetter Strasse 55 79106 Freiburg GermanyM. Steib-Bauert, Univers... Infection journals http://www.medworm.com/rss/comments.php?id=2264391 Wed, 11 Mar 2009 11:26:28 +0100 2264391 http://www.medworm.com/index.php?rid=2264393&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd2238414905275j0%2F Content Type Journal ArticleCategory CorrespondenceDOI 10.1007/s15010-008-8260-3Authors E. Weber, University Hospital Zurich Dept. of Medicine Zurich SwitzerlandH. F. Günthard, University Hospital Zurich Division of Infectious Diseases and Hospital Epidemiology Zurich SwitzerlandT. Schertler, University Hospital Zurich Institute of Diagnostic Radiology Zurich SwitzerlandJ. D. Seebach, University Hospital Zurich Dept. of Medicine Zurich Switzerland Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126 (Source: Infection) Infection journals http://www.medworm.com/rss/comments.php?id=2264393 Tue, 10 Mar 2009 07:52:38 +0100 2264393 http://www.medworm.com/index.php?rid=2264394&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fvk25h8737322k6m6%2F Content Type Journal ArticleCategory CorrespondenceDOI 10.1007/s15010-008-8113-0Authors N. Pandak, General Hospital “Dr. Josip Benčević” Dept. of Infectious Disease Andrije Štampara 42 Slavonski Brod 35000 CroatiaO. Đaković-Rode, University Hospital for Infectious Disease “Dr. Fran Mihaljević” Zagreb CroatiaI. Čabraja, General Hospital “Dr. Josip Benčević” Dept. of Infectious Disease Slavonski Brod CroatiaŽ. Krištof, County Institute for Public Health Nazorova bb Slavonski Brod CroatiaS. Kotarac, Clinical Hospital Split Dept. of Infectious Disease Split Croatia Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126 (Source: Infection) Infection journals http://www.medworm.com/rss/comments.php?id=2264394 Tue, 10 Mar 2009 07:52:37 +0100 2264394 http://www.medworm.com/index.php?rid=2264395&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fch8g16221jjt2563%2F Conclusions  Maximal viral suppression has a large impact on HIV progression, particularly in heavily pre-treated individuals. Our findings support the latest treatment guidelines, which have rapidly evolved from an initial lack of indication to suggestions, and finally to strong recommendations for achieving the goal of suppressing viremia. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-008-8142-8Authors M. Zaccarelli, National Institute for Infectious Diseases “Lazzaro Spallanzani” Clinical Dept. Via Portuense 292 00149 Rome ItalyP. Lorenzini, National Institute for Infectious Diseases “Lazzaro Spallanzani” Clinical Dept. Via Portuense 292 00149 Rome ItalyV. Tozzi, National Institute for Infectious Diseases “Lazzar... Infection journals http://www.medworm.com/rss/comments.php?id=2264395 Tue, 10 Mar 2009 07:52:36 +0100 2264395 http://www.medworm.com/index.php?rid=2134279&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu217m5n12m5m6687%2F Conclusions  Females are admitted to hospital earlier than males, probably as an indirect result of the Prevention of Mother-to-Child Transmission (PMTCT) public health initiative. An active search of HIV status in other members of the family (PMTCT-plus) may result in the detection of asymptomatic HIV-infected patients as well. A Plasmodium falciparum-positive smear during admission significantly impacted on outcome as well as low platelet count. Content Type Journal ArticleCategory Brief ReportDOI 10.1007/s15010-008-7406-7Authors N. Saleri, University of Brescia Institute for Infectious and Tropical Diseases Piazza Spedali Civili 1 25123 Brescia ItalyS. Capone, University of Brescia Institute for Infectious and Tropical Diseases Piazza Spedali Civili 1 25123 Brescia ... Infection journals http://www.medworm.com/rss/comments.php?id=2134279 Sat, 24 Jan 2009 12:15:08 +0100 2134279 http://www.medworm.com/index.php?rid=2134280&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F3l466126197567v9%2F Content Type Journal ArticleCategory EditorialDOI 10.1007/s15010-009-3109-yAuthors C. Ruef Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126 (Source: Infection) Infection journals http://www.medworm.com/rss/comments.php?id=2134280 Sat, 24 Jan 2009 12:15:05 +0100 2134280 http://www.medworm.com/index.php?rid=2134282&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr85123281224l686%2F Conclusion  Recommended empirical antibiotic regimens fail to achieve the desired effect in a substantial number of hospitalized patients with SBP. This has a negative impact on mortality. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-008-8060-9Authors A. Umgelter, Klinikum rechts der Isar, Technical University Munich 2nd Medical Department Ismaninger str. 22 81675 Munich GermanyW. Reindl, Klinikum rechts der Isar, Technical University Munich Institute of Medical Microbiology, Immunology and Hygiene Munich GermanyM. Miedaner, Klinikum rechts der Isar, Technical University Munich 2nd Medical Department Ismaninger str. 22 81675 Munich GermanyR. M. Schmid, Klinikum rechts der Isar, Technical University Munich 2nd Medical Departme... Infection journals http://www.medworm.com/rss/comments.php?id=2134282 Sat, 24 Jan 2009 12:15:04 +0100 2134282 http://www.medworm.com/index.php?rid=2134281&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F285735318100h126%2F Conclusions  In this population of patients with severe sepsis, patients with S. pneum CAP had a more severe dysregulation of coagulation, fibrinolysis, and inflammation than patients with non-S. pneum CAP; the former also developed significantly elevated levels of markers of thrombosis. Treatment with DrotAA was associated with significant improvements in protein C levels as well as markers of thrombosis. These characteristics may make patients with S. pneum CAP and severe sepsis particularly suited to derive a benefit from therapy with DrotAA.Infection 2009 Content Type Journal ArticleCategory Brief ReportDOI 10.1007/s15010-008-8128-6Authors G. M. Vail, Eli Lilly and Company DC 6024 Indianapolis IN 46285 USAY. J. Xie, Eli Lilly and Company DC 6024 Indianapolis IN 462... Infection journals http://www.medworm.com/rss/comments.php?id=2134281 Sat, 24 Jan 2009 12:15:04 +0100 2134281 http://www.medworm.com/index.php?rid=2134284&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq78625687171245v%2F Conclusions  Both GRSs were independent predictors of response in a multivariable logistic regression model. Nevertheless, cross-validation of these GRSs on different patient databases is required before their implementation in clinical practice. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-008-8065-4Authors M. M. Santoro, University of Rome “Tor Vergata” Dept. of Experimental Medicine Via Montpellier 1 00133 Rome ItalyA. Bertoli, University Hospital Tor Vergata Molecular Virology Rome ItalyP. Lorenzini, INMI Lazzaro Spallanzani Rome ItalyF. Ceccherini-Silberstein, University of Rome “Tor Vergata” Dept. of Experimental Medicine Via Montpellier 1 00133 Rome ItalyN. Gianotti, Vita-Salute San Raffaele University Clinic o... Infection journals http://www.medworm.com/rss/comments.php?id=2134284 Sat, 24 Jan 2009 12:15:03 +0100 2134284 http://www.medworm.com/index.php?rid=2134283&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F100j5453630722n4%2F Content Type Journal ArticleCategory Images in InfectionDOI 10.1007/s15010-008-8287-5Authors J. Capron, Paris 6 University Internal Medicine Dept., Tenon Hospital, AP-HP Paris FranceO. Steichen, Paris 6 University Internal Medicine Dept., Tenon Hospital, AP-HP Paris France Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126 (Source: Infection) Infection journals http://www.medworm.com/rss/comments.php?id=2134283 Sat, 24 Jan 2009 12:15:03 +0100 2134283 http://www.medworm.com/index.php?rid=2134286&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F02842602k1745k7t%2F Conclusion  The PaGIA showed a sensitivity comparable to that of other treponemal tests with an even better specificity. Advantages of the PaGIA are the fast reaction time of only 20 min and the simplicity of the procedure with minimal technical equipment. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-008-7082-7Authors S. Borelli, Stadtspital Triemli Zürich Dermatologisches Ambulatorium Herman-Greulich-str. 70 8004 Zürich SwitzerlandA. Monn, Stadtspital Triemli Zürich Institut für Medizinische Onkologie Zürich SwitzerlandJ. Meyer, Universitätsspital Zürich Dermatologische Klinik Zürich SwitzerlandU. Berger, Universität Bielefeld Statistik-Beratungs-Centrum Zürich GermanyH. P. Honegger, Stadtspital Triemli Züric... Infection journals http://www.medworm.com/rss/comments.php?id=2134286 Sat, 24 Jan 2009 12:15:02 +0100 2134286 http://www.medworm.com/index.php?rid=2134285&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F8115g643k881811p%2F Conclusion  The case-mix index and the number of reported infections explained some of the observed regional variations. However, the moderate value of the models in explaining these regional variations suggest that determinants which could not be explored in this preliminary study may also contribute to regional differences. Future studies should aim at collecting data for each individual hospital as well as data on possible determinants for hospital antibiotic consumption. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-008-7468-6Authors R. Benko, University of Szeged Dept. of Clinical Pharmacy Szikra u. 8 6725 Szeged HungaryM. Matuz, University of Szeged Dept. of Clinical Pharmacy Szikra u. 8 6725 Szeged HungaryP. Doro, Uni... Infection journals http://www.medworm.com/rss/comments.php?id=2134285 Sat, 24 Jan 2009 12:15:02 +0100 2134285 http://www.medworm.com/index.php?rid=2111938&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fqpv5083823j87374%2F Conclusion  The study suggests that nursing homes are a significant reservoir for MRSA. Statistical and PFGE analyses indicate a scenario where MRSA seems to be endemic and individual risk factors, namely recent hospitalizations and repeated antibiotic treatments, play a major role in the selection of drug-resistant organisms. Infection control measures should be coordinated among different health care settings, and the appropriate use of antibiotics has emerged as an important issue for improving the quality of care. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-008-8165-1Authors P. Brugnaro, Veneto Region SER – Epidemiological Dept. Via Ospedale 18 31033 Castelfranco Veneto TV ItalyU. Fedeli, Veneto Region SER – Epide... Infection journals http://www.medworm.com/rss/comments.php?id=2111938 Fri, 16 Jan 2009 13:10:05 +0100 2111938 http://www.medworm.com/index.php?rid=2111937&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fqh0x0282337px205%2F Conclusion  Our study underlines a dominant role of norovirus and toxigenic C. difficile as etiologic agents of acute gastroenteritis among the patients of general practitioners. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-008-8106-zAuthors S. Huhulescu, Österreichische Agentur für Gesundheit und Ernährungssicherheit (AGES) Spargelfeldstr. 191 1220 Vienna AustriaR. Kiss, Österreichische Agentur für Gesundheit und Ernährungssicherheit (AGES) Spargelfeldstr. 191 1220 Vienna AustriaM. Brettlecker, Österreichische Agentur für Gesundheit und Ernährungssicherheit (AGES) Spargelfeldstr. 191 1220 Vienna AustriaR. J. Cerny, Österreichische Agentur für Gesundheit und Ernährungssicherheit (AGES) Spargelfeldstr. 191 1220 Vi... Infection journals http://www.medworm.com/rss/comments.php?id=2111937 Fri, 16 Jan 2009 13:10:04 +0100 2111937 http://www.medworm.com/index.php?rid=2111939&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fym2143126j475w53%2F Conclusions  Empiric antibiotic treatment of PE may not adequately treat rare pathogens such as S. maltophilia. Administration of an effective systemic or intravitreal antibiotic treatment after identification of S. maltophilia may have contributed to the favorable clinical course and relatively low relapse frequency in our patients. Despite the known problem of persistence of S. maltophilia, visual acuity outcome after treatment is comparable to PE induced by other Gram-positive or Gram-negative bacteria. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-008-8150-8Authors S. Horster, Ludwig-Maximilians University Division of Infectious Diseases, Medizinische Poliklinik Munich GermanyL. Bader, Ludwig-Maximilians University Max von... Infection journals http://www.medworm.com/rss/comments.php?id=2111939 Fri, 16 Jan 2009 13:10:01 +0100 2111939 http://www.medworm.com/index.php?rid=2111940&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fpv56863614241347%2F Conclusion  The sensitive qPCR analysis proved to be a rapid and reliable method to detect P. jirovecii in BAL. Content Type Journal ArticleCategory Brief ReportDOI 10.1007/s15010-008-8027-xAuthors P. Rohner, University Hospitals of Geneva Medical Direction 24 rue Micheli-du-Crest 1211 Geneva 14 SwitzerlandV. Jacomo, Laboratoire Biomnis Lyon FranceR. Studer, University Hospitals of Geneva Central Bacteriologic Laboratory Geneva SwitzerlandJ. Schrenzel, University Hospitals of Geneva Central Bacteriologic Laboratory Geneva SwitzerlandJ.-D. Graf, University Hospitals of Geneva Laboratory for Biological Fluids Geneva Switzerland Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126 (Source: Infection) Infection journals http://www.medworm.com/rss/comments.php?id=2111940 Fri, 16 Jan 2009 13:10:00 +0100 2111940 http://www.medworm.com/index.php?rid=2103994&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fah5u61692th648h0%2F Conclusions  These results suggest that an early retreatment with leukocyte IFN-alpha may be a safe and valid therapeutic option among difficult-to-treat HCV cirrhotic patients who cannot tolerate PEG-IFNs. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-008-8164-2Authors B. Cacopardo, University of Catania Dept. of Internal Medicine and Medical Specialties, Institute of Infectious Diseases Via Passo Gravina 187 90157 Catania ItalyG. Nunnari, University of Catania Dept. of Internal Medicine and Medical Specialties, Institute of Infectious Diseases Via Passo Gravina 187 90157 Catania ItalyF. Benanti, University of Catania Dept. of Internal Medicine and Medical Specialties, Institute of Infectious Diseases Via Passo Gravina 187 90... Infection journals http://www.medworm.com/rss/comments.php?id=2103994 Tue, 13 Jan 2009 08:50:52 +0100 2103994 http://www.medworm.com/index.php?rid=2103995&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F1138918397v3x402%2F Conclusion  This pilot study is the first to compare QFT-G, ELISPOT, and TST in ESRD patients on hemodialysis and demonstrates a high prevalence of LTBI in this population. In our study, the QFT-G was the more accurate method for identifying those truly infected with Mycobacterium tuberculosis, even in BCG-vaccinated individuals. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-008-8082-3Authors S. S. J. Lee, Kaohsiung Veterans General Hospital Section of Infectious Diseases, Dept. of Medicine 386, Ta-chung 1st Rd. Kaohsiung 813 TaiwanK. J. Chou, National Yang-Ming University Taipei TaiwanI. J. Su, National Health Research Institutes Division of Clinical Research Miaoli TaiwanY. S. Chen, Kaohsiung Veterans General Hospital Sec... Infection journals http://www.medworm.com/rss/comments.php?id=2103995 Tue, 13 Jan 2009 08:50:47 +0100 2103995 http://www.medworm.com/index.php?rid=2103996&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq13ppm9825123578%2F Conclusion  The results of this study show that in pre-ulcerative Buruli ulcer disease, bacilli may extend beyond the actual size of the lesion and that there is a strong correlation between the presence of M. ulcerans in the margin samples and the surgical distance. Excision with a surgical distance of 25 mm avoided the risk of remaining mycobacteria in this study. However, no recurrences occurred in the patients with M. ulcerans-positive excision margins. The need of postoperative antimycobacterial treatment in these patients remains to be determined. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-008-8073-4Authors K.-H. Herbinger, Ludwig-Maximilian University Munich Dept. of Infectious Diseases and Tropical Medicine (D... Infection journals http://www.medworm.com/rss/comments.php?id=2103996 Tue, 13 Jan 2009 08:50:44 +0100 2103996 http://www.medworm.com/index.php?rid=2103997&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg302881532356820%2F Content Type Journal ArticleCategory CorrespondenceDOI 10.1007/s15010-008-7353-3Authors A. Kadanali, Atatürk University Dept. of Infectious Diseases, School of Medicine Erzurum TurkeyK. Ozden, Atatürk University Dept. of Infectious Diseases, School of Medicine Erzurum TurkeyU. Altoparlak, Atatürk University Dept. of Microbiology and Clinical Microbiology, School of Medicine Erzurum TurkeyA. Erturk, Atatürk University Dept. of Infectious Diseases, School of Medicine Erzurum TurkeyM. Parlak, Atatürk University Dept. of Infectious Diseases, School of Medicine Erzurum Turkey Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126 (Source: Infection) Infection journals http://www.medworm.com/rss/comments.php?id=2103997 Tue, 13 Jan 2009 08:50:40 +0100 2103997 http://www.medworm.com/index.php?rid=2103998&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F8835868538258373%2F Conclusions  Providing easy access to vaccination in the wards is a useful approach for improving vaccination rates among HCWs, but further tailored interventions are needed because overall vaccination rates remain too low. Subgroups, such as nurses and ancillary staff, should be considered as specific targets of such vaccination programs. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-008-8002-6Authors M. Chittaro, University Hospital of Udine Medical Direction Piazzale S. Maria della Misericordia, 15 33100 Udine ItalyD. Turello, University of Udine Medical Direction, Chair of Hygiene, Dept. of Clinical and Experimental Pathology and Medicine (DPMSC) Udine ItalyL. Calligaris, University of Udine Medical Direction, Chair of Hy... Infection journals http://www.medworm.com/rss/comments.php?id=2103998 Tue, 13 Jan 2009 08:50:36 +0100 2103998 http://www.medworm.com/index.php?rid=2103999&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fcm51274u6805u571%2F Conclusions  In comparison with the two previous studies, the overall incidence of intracranial abscesses is decreasing on Merseyside. Moreover, the predisposing factors for intracranial abscesses have changed over the decades. The number of otogenic cases has declined. The incidence of brain abscesses following neurosurgical procedures is still a major cause for concern, as is the emergence of MRSA, as a significant pathogen. Content Type Journal ArticleCategory Brief ReportDOI 10.1007/s15010-008-7359-xAuthors R. Sharma, University Hospital Aintree Dept. of Medical Microbiology Lower Lane Liverpool L9 7AL UKK. Mohandas, University Hospital Aintree Dept. of Medical Microbiology Lower Lane Liverpool L9 7AL UKR. P. D. Cooke, University Hospital Aintree Dept. of Medical ... Infection journals http://www.medworm.com/rss/comments.php?id=2103999 Tue, 13 Jan 2009 08:28:59 +0100 2103999 http://www.medworm.com/index.php?rid=2104000&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu217711132t77208%2F Conclusions  The introduction of the CPP significantly improved compliance of hand decontamination, correct usage of gloves and aprons, and overall infection-control in a large teaching hospital. The CPP is a highly effective auditing and educational tool that can be readily adapted for use in hospitals globally to monitor and improve infection-control practices. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-008-8005-3Authors D. P. J. Howard, Oxford Radcliffe Hospitals Trust Dept. of Surgery Oxford UKC. Williams, Barnet General Hospital Dept. of Surgery London UKS. Sen, Barnet General Hospital Dept. of Surgery London UKA. Shah, Barnet General Hospital Dept. of Surgery London UKJ. Daurka, Barnet General Hospital Dept. of Surge... Infection journals http://www.medworm.com/rss/comments.php?id=2104000 Tue, 13 Jan 2009 08:28:56 +0100 2104000 http://www.medworm.com/index.php?rid=2104001&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fcwt417g267741342%2F Conclusion  Our findings confirm the importance of a comprehensive approach to the vaccination, ensuring that HCWs are correctly informed about the vaccine and that it is convenient to receive it. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-008-8200-2Authors S. Wicker, Johann Wolfgang Goethe University of Frankfurt Occupational Health Service, University Hospital Frankfurt/Main GermanyH. F. Rabenau, Johann Wolfgang Goethe University of Frankfurt Institute of Medical Virology and Travel Vaccination Centre, University Hospital Paul-Ehrlich-Str. 40 60596 Frankfurt/Main GermanyH. W. Doerr, Johann Wolfgang Goethe University of Frankfurt Institute of Medical Virology and Travel Vaccination Centre, University Hospital Paul-Ehrlich-... Infection journals http://www.medworm.com/rss/comments.php?id=2104001 Tue, 13 Jan 2009 07:57:03 +0100 2104001 http://www.medworm.com/index.php?rid=2104002&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F41k55234k6p88082%2F Conclusions  In COPD patients admitted to the general ward, acute exacerbation with MDRP in sputum was associated with higher mortality. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-008-8125-9Authors M. Montero, Hospital del Mar, Autonomous University of Barcelona Dept. of Internal Medicine and Infectious Diseases Paseo Marítimo 25-29 08003 Barcelona SpainM. Domínguez, Hospital del Mar Dept. of Pneumology Barcelona SpainM. Orozco-Levi, Hospital del Mar Dept. of Pneumology Barcelona SpainM. Salvadó, Laboratorio de Referencia de Catalunya Dept. of Microbiology Barcelona SpainH. Knobel, Hospital del Mar, Autonomous University of Barcelona Dept. of Internal Medicine and Infectious Diseases Paseo Marítimo 25-29 08003 Barcelona ... Infection journals http://www.medworm.com/rss/comments.php?id=2104002 Tue, 13 Jan 2009 07:56:59 +0100 2104002 http://www.medworm.com/index.php?rid=2097576&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj435583862076615%2F Content Type Journal ArticleCategory CorrespondenceDOI 10.1007/s15010-008-8214-9Authors J. J. Wenzel, University of Regensburg Institute for Medical Microbiology and Hygiene Franz-Josef-Strauß-Allee 11 93053 Regensburg GermanyJ. Hentschel, Children’s Hospital St. Marien Landshut GermanyW. Silvis, University of Regensburg Institute for Medical Microbiology and Hygiene Franz-Josef-Strauß-Allee 11 93053 Regensburg GermanyW. Permanetter, Klinikum Landshut Institute of Pathology Landshut GermanyJ. Mattes, Microbiology Laboratory Dr. Mattes Dr. Kochanowski Neuötting GermanyB. Kochanowski, Microbiology Laboratory Dr. Mattes Dr. Kochanowski Neuötting GermanyR. Herterich, Children’s Hospital St. Marien Landshut GermanyW. Jilg, University of Regensburg Institute for Medical Microbiology ... Infection journals http://www.medworm.com/rss/comments.php?id=2097576 Sat, 10 Jan 2009 10:43:03 +0100 2097576 http://www.medworm.com/index.php?rid=2097577&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa080461244471534%2F Conclusion  The known greater selective effect of long-acting agents could establish a pressure outcome, resulting in a specific local epidemiology during a relatively short time gap. Content Type Journal ArticleCategory Brief ReportDOI 10.1007/s15010-008-8023-1Authors F. Montagnani, University of Siena, Ospedale Le Scotte Clinic and Laboratory of Infectious Diseases, Molecular Biology Department Piano o lotto IV, Viale Bracci, 16 53100 Siena ItalyL. Stolzuoli, University of Siena, Ospedale Le Scotte Clinic and Laboratory of Infectious Diseases, Molecular Biology Department Piano o lotto IV, Viale Bracci, 16 53100 Siena ItalyL. Croci, University of Siena, Ospedale Le Scotte Clinic and Laboratory of Infectious Diseases, Molecular Biology Department Piano o lotto IV, Vial... Infection journals http://www.medworm.com/rss/comments.php?id=2097577 Sat, 10 Jan 2009 10:43:02 +0100 2097577 http://www.medworm.com/index.php?rid=1979530&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb561k64013868756%2F Content Type Journal ArticleCategory ErratumDOI 10.1007/s15010-008-9357-4Authors O. A. Cornely, Klinikum der Universität zu Köln Klinik I für Innere Medizin 50924 Cologne Germany Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126 (Source: Infection) Infection journals http://www.medworm.com/rss/comments.php?id=1979530 Thu, 20 Nov 2008 08:18:07 +0100 1979530 http://www.medworm.com/index.php?rid=1979533&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2m1805576x6055p4%2F Conclusion  A combination of symptoms not necessarily considered indicative of dengue diagnosis could improve surveillance and medical decision-making in simple clinical settings. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-008-7334-6Authors S. R. L. Passos, Evandro Chagas Clinical Research Institute Clinical Epidemiology Laboratory Av Brasil 4365 Manguinhos Rio de Janeiro 21045900 BrazilS. J. Bedoya, Evandro Chagas Clinical Research Institute Clinical Epidemiology Laboratory Av Brasil 4365 Manguinhos Rio de Janeiro 21045900 BrazilY. H. M. Hökerberg, Evandro Chagas Clinical Research Institute Clinical Epidemiology Laboratory Av Brasil 4365 Manguinhos Rio de Janeiro 21045900 BrazilS. C. Maia, Evandro Chagas Clinical Research... Infection journals http://www.medworm.com/rss/comments.php?id=1979533 Thu, 20 Nov 2008 08:18:06 +0100 1979533 http://www.medworm.com/index.php?rid=1979532&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa22w55543631m873%2F Content Type Journal ArticleCategory CommentaryDOI 10.1007/s15010-008-8090-3Authors E. J. Young, VA Medical Center Section of Infectious Diseases 2002 Holcombe Bivd Houston TX USA Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126 (Source: Infection) Infection journals http://www.medworm.com/rss/comments.php?id=1979532 Thu, 20 Nov 2008 08:18:06 +0100 1979532 http://www.medworm.com/index.php?rid=1979531&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj4u66565j12g3440%2F Content Type Journal ArticleCategory EditorialDOI 10.1007/s15010-008-3608-2Authors C. Ruef Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126 (Source: Infection) Infection journals http://www.medworm.com/rss/comments.php?id=1979531 Thu, 20 Nov 2008 08:18:06 +0100 1979531 http://www.medworm.com/index.php?rid=1967949&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl34700hj58223347%2F Conclusions  Formal outpatient ID consultations have unique aspects, which differ from “traditional” inpatient consultations. The field offers exciting medical research possibilities and new themes for healthcare executives. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-008-7397-4Authors M. Grupper, Bnai Zion Medical Center Infectious Diseases Unit P.O. Box 4940 31048 Haifa IsraelI. Potasman, Bnai Zion Medical Center Infectious Diseases Unit P.O. Box 4940 31048 Haifa Israel Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126 (Source: Infection) Infection journals http://www.medworm.com/rss/comments.php?id=1967949 Sun, 16 Nov 2008 11:49:04 +0100 1967949 http://www.medworm.com/index.php?rid=1967948&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F53k6x67814k2n204%2F Conclusions  IA remains therefore associated with a high-mortality rate, especially in patients with neutropenia. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-008-7375-xAuthors S. Gallien, Hôpital Saint-Louis, Assistance Publique Hôpitaux de Paris, University of Paris 7 Infectious Disease Dept. 1, Avenue Claude Vellefaux Paris Cedex 10 75475 FranceS. Fournier, Hôpital Saint-Louis, Assistance Publique Hôpitaux de Paris, University of Paris 7 Infectious Disease Dept. 1, Avenue Claude Vellefaux Paris Cedex 10 75475 FranceR. Porcher, Hôpital Saint-Louis, Assistance Publique Hôpitaux de Paris, University of Paris 7 Biostatistic Dept. Paris FranceJ. Bottero, Hôpital Saint-Louis, Assistance Publique Hôpitaux de Paris, Unive... Infection journals http://www.medworm.com/rss/comments.php?id=1967948 Sun, 16 Nov 2008 11:49:04 +0100 1967948 http://www.medworm.com/index.php?rid=1967947&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F5509v807053nx375%2F Conclusion  This study has confirmed that establishing a targeted LAMP, based on close co-operation between intensive care physicians and infectious disease specialists together with a restricted prescribing authority, can reduce the use of antibiotics. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-008-7377-8Authors Z. Peto, University of Szeged Dept. of Anaesthesiology and Intensive Care Semmelweis u. 6. 6725 Szeged HungaryR. Benko, University of Szeged Dept. of Clinical Pharmacy Szeged HungaryM. Matuz, University of Szeged Dept. of Clinical Pharmacy Szeged HungaryE. Csullog, University of Szeged Dept. of Anaesthesiology and Intensive Care Semmelweis u. 6. 6725 Szeged HungaryA. Molnar, University of Szeged Dept. of Anaesthesi... Infection journals http://www.medworm.com/rss/comments.php?id=1967947 Sun, 16 Nov 2008 11:49:04 +0100 1967947 http://www.medworm.com/index.php?rid=1967951&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk454206705u1r65g%2F Content Type Journal ArticleCategory Images in InfectionDOI 10.1007/s15010-008-8244-3Authors D. Tappe, University of Würzburg Institute of Hygiene and Microbiology Josef-Schneider-Str.2 97080 Würzburg GermanyR. Melcher, University Hospital of Würzburg Clinic of Medicine and Outpatients’ Clinic II Würzburg GermanyM. Maier, University Hospital of Würzburg Surgical Clinic I Würzburg GermanyW. Kenn, University Hospital of Würzburg Dept. of Radiology Würzburg GermanyK. Müller-Hermelink, University of Würzburg Institute of Pathology Würzburg GermanyM. Frosch, University of Würzburg Institute of Hygiene and Microbiology Josef-Schneider-Str.2 97080 Würzburg Germany Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126 (Source: Infection) Infection journals http://www.medworm.com/rss/comments.php?id=1967951 Sun, 16 Nov 2008 11:49:03 +0100 1967951 http://www.medworm.com/index.php?rid=1967950&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu73n41t63mx36275%2F In conclusion, family members of the patients with brucellosis are under the increased risk of brucellosis because of a common source. Therefore, it can be considered that family screening may lead to early diagnosis of the disease and to the prevention of the complications. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-008-7022-6Authors F. Tabak, University of Istanbul Cerrahpasa Medical Faculty, Dept. of Infectious Diseases and Clinical Microbiology 34303 Aksaray, Istanbul TurkeyE. Hakko, University of Istanbul Cerrahpasa Medical Faculty, Dept. of Infectious Diseases and Clinical Microbiology 34303 Aksaray, Istanbul TurkeyB. Mete, University of Istanbul Cerrahpasa Medical Faculty, Dept. of Infectious Diseases and Clinical Microbiolog... Infection journals http://www.medworm.com/rss/comments.php?id=1967950 Sun, 16 Nov 2008 11:49:03 +0100 1967950 http://www.medworm.com/index.php?rid=1967952&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb2730063r508771j%2F Conclusions  Data on in-hospital antimicrobial use vary widely not only due to different antibiotic policies at different institutions but also due to different methods of measures. Adherence to the standard of reporting the methods of measurement is warranted for benchmarking and promotion of rational antimicrobial use. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-008-7462-zAuthors S. P. Kuster, University Hospital Zurich Division of Infectious Diseases and Hospital Epidemiology Rämistrasse 100 8091 CH Zurich SwitzerlandC. Ruef, University Hospital Zurich Division of Infectious Diseases and Hospital Epidemiology Rämistrasse 100 8091 CH Zurich SwitzerlandB. Ledergerber, University Hospital Zurich Division of Infectious Dis... Infection journals http://www.medworm.com/rss/comments.php?id=1967952 Sun, 16 Nov 2008 11:49:02 +0100 1967952 http://www.medworm.com/index.php?rid=1951169&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb765068g3219258p%2F We report a case of rhinofacial C. coronatus infection in an emigrated Sudanese patient. The infection was successfully treated with terbinafin and itraconazole for 12 months. Diagnosis was confirmed by microbiological culture from a tissue biopsy. Antimicrobial susceptibility testing of this organism was not predictive of optimal therapy. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s15010-008-8056-5Authors N. Fischer, University Hospital Dept. of Medicine, Medical Clinic Zurich SwitzerlandCh. Ruef, University Hospital of Zurich Division of Infectious Diseases and Hospital Epidemiology Zurich SwitzerlandC. Ebnöther, Hospital of Langenthal Dept. of Internal Medicine Langenthal SwitzerlandE. B. Bächli, Hospital of Uster Medical Clinic Brunnenstrasse 8610 Uster... Infection journals http://www.medworm.com/rss/comments.php?id=1951169 Sun, 09 Nov 2008 09:56:56 +0100 1951169 http://www.medworm.com/index.php?rid=1951170&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft3113352840127v8%2F Conclusion  IL-6 levels were increased in pulmonary tuberculosis, independent of drug resistance. Content Type Journal ArticleCategory Brief ReportDOI 10.1007/s15010-008-7398-3Authors J. W. Correia, Hospital Geral Dr César Cals Internal Medicine Unit Fortaleza CE BrazilM. V. Freitas, Federal University of Ceará Dept. of Pathology, Faculty of Medicine Rua Monsenhor Furtado s/n Fortaleza CE CEP: 60441-750 BrazilJ. A. Queiroz, Federal University of Ceará Dept. of Pathology, Faculty of Medicine Rua Monsenhor Furtado s/n Fortaleza CE CEP: 60441-750 BrazilM. PereiraPerrin, Tufts University School of Medicine Boston MA USAB. Cavadas, Federal University of Ceará Dept. of Chemistry Fortaleza CE Brazil Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126 (Source: ... Infection journals http://www.medworm.com/rss/comments.php?id=1951170 Sun, 09 Nov 2008 09:56:55 +0100 1951170 http://www.medworm.com/index.php?rid=1951172&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr663268u22978760%2F Conclusions  Many professions, especially those involving outdoor activities, are associated with increased environmental exposure to pathogenic fungi and, subsequently, increased risk of IFIs. Inhalation and direct inoculation through minor skin lesions are the most common mechanisms of fungal infection. In addition, different lifestyle practices, such as smoking tobacco or marijuana, body piercing, tattooing, use of illicit intravenous drugs, and pet ownership, various outdoor leisure activities, such as gardening, camping, spelunking, and hunting, and traveling to endemic areas are associated with an increased risk of IFIs. Finally, some modern diet habits dictate the consumption of food or herbal products harboring pathogenic fungi or fungal toxins, which may cause IFIs... Infection journals http://www.medworm.com/rss/comments.php?id=1951172 Sun, 09 Nov 2008 09:56:54 +0100 1951172 http://www.medworm.com/index.php?rid=1951171&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F287786r1207161w0%2F Conclusion  In our small study, US seemed to underestimate hidden liver fibrosis in intestinal schistosomiasis. In some European clinical settings, histological evaluation by liver biopsy may be a useful tool to detect early liver pathology in schistosomiasis mansoni. These findings could provide additional information for studies from endemic areas where US is commonly used for morbidity assessment. Content Type Journal ArticleCategory Brief ReportDOI 10.1007/s15010-008-7202-4Authors R. Chiavaroli, “S. Caterina Novella” Hospital Infectious Disease Unit 73013 Galatina, Lecce ItalyP. Grima, “S. Caterina Novella” Hospital Infectious Disease Unit 73013 Galatina, Lecce ItalyP. Grima, “S. Caterina Novella” Hospital Infectious Disease Unit 73013 Galatina, Lecce ... Infection journals http://www.medworm.com/rss/comments.php?id=1951171 Sun, 09 Nov 2008 09:56:54 +0100 1951171 http://www.medworm.com/index.php?rid=1926236&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F64760k4807414w50%2F Content Type Journal ArticleCategory CorrespondenceDOI 10.1007/s15010-008-8035-xAuthors A. Castella, University of Turin Dept. of Public Health and Microbiology Turin ItalyP. A. Argentero, Rivoli Hospital Infection Control Unit Rivoli, Turin ItalyE. C. Farina, Molinette Hospital Dept. of Surgery Turin ItalyE. Anselmo, University of Turin Dept. of Public Health and Microbiology Via Santena 5bis 10126 Turin ItalyA. Djiomo, University of Turin Dept. of Public Health and Microbiology Via Santena 5bis 10126 Turin ItalyC. M. Zotti, University of Turin Dept. of Public Health and Microbiology Via Santena 5bis 10126 Turin ItalyPiemonte Nosocomial Infection Study Group Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126 (Source: Infection) Infection journals http://www.medworm.com/rss/comments.php?id=1926236 Fri, 31 Oct 2008 07:16:53 +0100 1926236 http://www.medworm.com/index.php?rid=1926235&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe35101t6833475m3%2F Conclusion  Type IV/IVA has become the most common SCCmec type in inpatients of our university hospital. The SCCmec type IV/IVA is present in both CA-MRSA and HA-MRSA limiting its use as a marker for CA-MRSA. Content Type Journal ArticleCategory Brief ReportDOI 10.1007/s15010-008-7430-7Authors A.M. Strandén, University Hospital Basel Infection Control and Hospital Epidemiology Basel SwitzerlandR. Frei, University Hospital Basel Infection Control and Hospital Epidemiology Basel SwitzerlandH. Adler, University Hospital Basel Infection Control and Hospital Epidemiology Basel SwitzerlandU. Flückiger, University Hospital Basel Infection Control and Hospital Epidemiology Basel SwitzerlandA. F. Widmer, University Hospital Basel Infection Control and Hospital Epidemiology Base... Infection journals http://www.medworm.com/rss/comments.php?id=1926235 Fri, 31 Oct 2008 07:16:53 +0100 1926235 http://www.medworm.com/index.php?rid=1926238&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm502j178mk54k153%2F Conclusion  Contamination may frequently be present even in the setting of the recovery of CoNS from two or more blood culture sets within 24 h. Speciation of CoNS bloodstream isolates is rapid and may improve patient care as well as reduce unnecessary antibiotic use. Content Type Journal ArticleCategory Brief ReportDOI 10.1007/s15010-008-8020-4Authors U. Seybold, Ludwig-Maximilians-Universität Division of Infectious Diseases, Medizinische Poliklinik Pettenkoferstr. 8a 80336 Munich GermanyC. Reichardt, Hannover Medical School Institute of Medical Microbiology and Hospital Epidemiology Hannover GermanyJ. S. Halvosa, Grady Memorial Hospital Epidemiology Dept. Atlanta USAH. M. Blumberg, Emory University, School of Medicine Division of Infectious Diseases, Dept. of M... Infection journals http://www.medworm.com/rss/comments.php?id=1926238 Fri, 31 Oct 2008 07:16:52 +0100 1926238 http://www.medworm.com/index.php?rid=1926237&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw2l782n01wt6x470%2F Conclusion  Our findings show that, from an experimental point of view, it remains controversial whether routine change of closed suction catheters can be extended from 24 h to 72 h. However, clinical evidence suggests that prolonged use of a closed suctioning system is safe. Content Type Journal ArticleCategory Brief ReportDOI 10.1007/s15010-008-7444-1Authors E. Meyer, University Medical Center, Freiburg Dept. of Environmental Health Sciences Freiburg GermanyM. Schuhmacher, University Medical Center, Freiburg Dept. of Environmental Health Sciences Freiburg GermanyW. Ebner, University Medical Center, Freiburg Dept. of Environmental Health Sciences Freiburg GermanyM. Dettenkofer, University Medical Center, Freiburg Dept. of Environmental Health Sciences Freiburg Ge... Infection journals http://www.medworm.com/rss/comments.php?id=1926237 Fri, 31 Oct 2008 07:16:52 +0100 1926237 http://www.medworm.com/index.php?rid=1894131&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy6q066nj17682000%2F Abstract  Recently, important advances have been made in the immunodiagnosis of tuberculosis. New T cell interferon-γ release assays (TIGRA) are more specific and more sensitive than the tuberculin skin test (TST) for the diagnosis of Mycobacterium tuberculosis (MTB) infection. However, like the TST, TIGRA are unable to distinguish between active tuberculosis (TB), latent TB infection (LTBI) and treated TB if performed on blood mononuclear cells alone. In active TB, MTB-specific T cells are actively recruited to the site of infection and can rapidly be identified in extrasanguinous fluids, such as pleural effusions, ascites, cerebrospinal fluid, and in bronchoalveolar lavages. This review summarizes recent findings comparing systemic and local immune responses against MTB. ... Infection journals http://www.medworm.com/rss/comments.php?id=1894131 Sun, 19 Oct 2008 10:10:25 +0100 1894131 http://www.medworm.com/index.php?rid=1883023&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa2mg563g64u747lv%2F Conclusions  Melioidosis can occur sporadically or in a cluster in diabetic patients during rainy seasons in Taiwan. Content Type Journal ArticleCategory Clinical and Epidemiological StudyDOI 10.1007/s15010-008-7324-8Authors H.-I. Shih, National Cheng Kung University Hospital Dept. of Internal Medicine Dou-Liou Branch Yunlin TaiwanY.-C. Chuang, Chi Mei Medical Center Dept. of Medical Research Tainan TaiwanB. M.-H. Cheung, Tainan Municipal Hospital Dept. of Internal Medicine Tainan TaiwanJ.-J. Yan, National Cheng Kung University Hospital Dept. of Pathology Tainan TaiwanC.-M. Chang, National Cheng Kung University Hospital Dept. of Internal Medicine No. 138, Sheng Li Road Tainan 70403 TaiwanK. Chang, Tainan Municipal Hospital Dept. of Internal Medicine Tainan TaiwanN.-Y. Le... Infection journals http://www.medworm.com/rss/comments.php?id=1883023 Wed, 15 Oct 2008 10:55:18 +0100 1883023 http://www.medworm.com/index.php?rid=1883022&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft1u7154085vtx276%2F Abstract  Bacillus Calmette–Guérin (BCG) vaccine has a good safety profile in immune competent children and considerable risks such as disseminated BCG disease in individuals with immune deficiencies. However, some complications including local subcutaneous infection, regional suppurative lymphadenitis may occur after BCG vaccination in immune competent children. A 17-month-old female child was admitted with a painless protruding mass on the anterior chest wall. There was no evidence of previous tuberculous infection and contact with a tuberculosis patient. Chest-computed tomography revealed an oval shaped low attenuated 1.8 × 1.0 cm mass at subcutaneous and muscle layers just below sternum, but the pulmonary parenchyma seemed to be normal. We excised the ... Infection journals http://www.medworm.com/rss/comments.php?id=1883022 Wed, 15 Oct 2008 10:55:18 +0100 1883022 http://www.medworm.com/index.php?rid=1883021&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb54854n8q48355t7%2F We describe a case of chronic fistulae caused by a coinfection with A. europaeus and A. turicensis in an immunocompetent male patient with a severe congenital femur hypoplasia. Actinomycosis is most probably the consequence of a postoperative wound infection after a prior surgical intervention. Both Actinomyces species were identified by 16S rRNA gene sequencing. The Actinomyces-caused fistulae were treated by excision and a 1-week course of i.v. vancomycin followed by a 1-week course of p.o. cefuroxime. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s15010-008-7392-9Authors A. E. Zautner, University Hospital Rostock Institute of Medical Microbiology, Virology and Hygiene Schillingallee 70 18057 Rostock GermanyS. Schmitz, University Hospital Rostock Orthopaedic Hospital ... Infection journals http://www.medworm.com/rss/comments.php?id=1883021 Wed, 15 Oct 2008 10:55:18 +0100 1883021 http://www.medworm.com/index.php?rid=1883020&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F4p3j164215088vh3%2F Conclusion  Vaccination should be only regarded as “successful”, if the post-vaccination anti-HBs concentration is at least 100 IU/l. Content Type Journal ArticleCategory Brief ReportDOI 10.1007/s15010-008-7410-yAuthors F. Hofmann, University of Wuppertal Chair for Physiology Occupational Medicine and Prevention of Infectious diseases Gauss Str. 20 42349 Wuppertal GermanyN. Kralj, University of Wuppertal Chair for Physiology Occupational Medicine and Prevention of Infectious diseases Gauss Str. 20 42349 Wuppertal Germany Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126 (Source: Infection) Infection journals http://www.medworm.com/rss/comments.php?id=1883020 Wed, 15 Oct 2008 10:55:18 +0100 1883020 http://www.medworm.com/index.php?rid=1883025&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh8882665g750gh07%2F Conclusions  We demonstrated, in the present study, the incidence of IA in leukemic patients and the usefulness of molecular assay for early diagnosis and monitoring of the treatment of IA. Content Type Journal ArticleCategory Brief ReportDOI 10.1007/s15010-008-7385-8Authors P. Badiee, Shiraz University of Medical Sciences, Nemazi Hospital Prof. Alborzi Clinical Microbiology Research Center Zand Ave Shiraz IranP. Kordbacheh, Tehran University of Medical Sciences Dept. of Medical Parasitology and Mycology, School of Public Health and Institute of Public Health Research Tehran IranA. Alborzi, Shiraz University of Medical Sciences, Nemazi Hospital Prof. Alborzi Clinical Microbiology Research Center Zand Ave Shiraz IranM. Ramzi, Shiraz University of Medical Sciences Dept.... Infection journals http://www.medworm.com/rss/comments.php?id=1883025 Wed, 15 Oct 2008 10:55:17 +0100 1883025 http://www.medworm.com/index.php?rid=1883024&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh20x685uj6x5r410%2F This report documents the feasibility and clinical usefulness of an Interferon (IFN) – gamma ELISpot – TB assay on pericardial fluid cells in a case of suspected tuberculous pericarditis presenting with tamponade. As large pericardial effusions requiring pericardiocentesis are relatively frequent in tuberculous pericarditis, the physician may consider this particular application of ELISpot–TB as a rapid decision aid for starting the treatment. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s15010-008-7402-yAuthors A. Biglino, University of Torino Dept. of Medical and Surgical Disciplines Torino ItalyP. Crivelli, “Cardinal Massaia” Hospital Infectious and Tropical Diseases Unit Corso Dante 202 14100 Asti ItalyE. Concialdi, “Cardinal Massaia” Hospital Infe... Infection journals http://www.medworm.com/rss/comments.php?id=1883024 Wed, 15 Oct 2008 10:55:17 +0100 1883024 http://www.medworm.com/index.php?rid=1832523&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fdq6277000j931682%2F Summary  A multicenter, double-blinded, placebo-controlled study was done comparing a 30-μg dose of a single protein recombinant OspA vaccine preparation with a saline placebo for efficacy in prevention of Lyme disease in humans. The OspA vaccine (30-μg dose) or saline placebo was given intramuscularly at day 0,1 month later, and 12 months later. Cases of possible Lyme disease were evaluated clinically and using culture, polymerase chain reaction and immunoblot assays. Safety data are being analyzed separately. 1,634 adult volunteers were enrolled at a single center in New York State. Vaccine efficacy during the first year was 40% and during the second 37%. Compared with placebo, the OspA vaccine significantly reduced the frequency of Lyme disease during the 2-year study ... Infection journals http://www.medworm.com/rss/comments.php?id=1832523 Thu, 25 Sep 2008 07:39:48 +0100 1832523 http://www.medworm.com/index.php?rid=1832525&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Flw53727xw0157103%2F Summary  A randomized, double-blind trial compared treatment with the immune modulator WF10 (ten patients) and placebo (nine patients) administered in cycles over 3 months among individuals with advanced AIDS. There were no notable clinical adverse events; changes in hematologic and chemistry values were comparable in the two groups. In both groups, median HIV-RNA PCR values remained stable. Immunologic variables showed a consistent tendency to increase in the WF10 group and to decrease in the control group, with significant differences between groups for median WBC, lymphocyte, CD19, and CD35 values. Ten infections occurred in the control group, four of which werePneumocystis carinii pneumonia (PCP), and three in the WF10 group none of which was PCP. Five patients in the co... Infection journals http://www.medworm.com/rss/comments.php?id=1832525 Thu, 25 Sep 2008 07:39:47 +0100 1832525 http://www.medworm.com/index.php?rid=1832524&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F51344q3171nq755m%2F Summary  A prospective study was performed to assess the potential value of interleukin (IL)-8, IL-6, and C-reactive protein (CRP) serum levels to predict fever, gram-negative bacteremia and complicated infection in neutropenic patients with cancer. Serum samples were obtained three times a week during 208 neutropenic episodes following cytotoxic chemotherapy. Fever of any cause developed during 104 out of 191 evaluable episodes. Serum levels of neither cytokine nor CRP were predictive of fever within more than 24 h before its onset. Unlike CRP, both IL-6 and IL-8 serum levels were significantly different between microbiologically documented infections and unexplained fevers. The highest values of IL-6 and IL-8 were observed in episodes of gram-negative bacteremia. Using re... Infection journals http://www.medworm.com/rss/comments.php?id=1832524 Thu, 25 Sep 2008 07:39:47 +0100 1832524 http://www.medworm.com/index.php?rid=1832526&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu8n7n82006n56211%2F Content Type Journal ArticleDOI 10.1007/BF02962363Authors W. Marget Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126 Journal Volume Volume 26 Journal Issue Volume 26, Number 4 / July, 1998 (Source: Infection) Infection journals http://www.medworm.com/rss/comments.php?id=1832526 Thu, 25 Sep 2008 07:39:46 +0100 1832526 http://www.medworm.com/index.php?rid=1832527&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk369w262n3484171%2F Summary  Between 1 November 1993 and 31 October 1996, admissions to paediatric departments forBordetella pertussis complications were reported to a nationwide, hospitalbased active surveillance system. The case definition included pertussis complicated by pneumonia, apnoea requiring assisted ventilation, seizures, encephalopathy or a combination of these. Two hundred sixteen cases of pertussis complications were registered. 57.4% of them were in infants, 50.9% of them less than 6 months old. There were five deaths, three previously healthy children died. At the time of hospital admission, 106 cases would have been eligible for at least three doses of pertussis vaccine, only four (3.8%) had received the recommended number of immunisations From the second quarter of 1995, the ... Infection journals http://www.medworm.com/rss/comments.php?id=1832527 Thu, 25 Sep 2008 07:39:45 +0100 1832527 http://www.medworm.com/index.php?rid=1832528&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F3855k03644528133%2F Summary  Concerns about the association of aseptic meningitis with measles-mumpsrubella (MMR) vaccines containing the Urabe Am 9 strain and the increasing worldwide demand for MMR vaccines, prompted the development of a new mumps vaccine strain (RIT 4385) by SmithKline Beecham Biologicals (SB) as part of a trivalent live attenuated MMR vaccine. The present study assessed the immunogenicity and reactogenicity of two lots of ‘Priorix’* with a widely used and established vaccine M-M-R II (Merck & Co. Inc.) as comparator vaccine. 255 healthy children, 12 to 24 months of age, were enrolled in a single-blind study and randomly allocated to receive a single dose of one of two lots of “Priorix” or M-M-R II vaccine. Vaccinees were followed up for six weeks post-vaccination fo... Infection journals http://www.medworm.com/rss/comments.php?id=1832528 Thu, 25 Sep 2008 07:39:44 +0100 1832528 http://www.medworm.com/index.php?rid=1832529&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj8433q0gu318m8m1%2F This study shows that of the AZI therapies used so far, combinations of AZI and tinidazole are the most successful at eradicatingH. pylori. Content Type Journal ArticleCategory AddendumDOI 10.1007/BF02962382Authors W. Dohmen, Lehrpraxis für Allgemeinmedizin Thomashofstr. 3 D-57070 Aachen GermanyR. E. A. Seelis, Gastroenterologische Facharztpraxis Theaterpl. 9–11 D-52062 Aachen Germany Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126 Journal Volume Volume 26 Journal Issue Volume 26, Number 4 / July, 1998 (Source: Infection) Infection journals http://www.medworm.com/rss/comments.php?id=1832529 Thu, 25 Sep 2008 07:39:43 +0100 1832529 http://www.medworm.com/index.php?rid=1832532&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq6506un200601418%2F Content Type Journal ArticleCategory CorrespondenceDOI 10.1007/BF02962380Authors P. M. Shah, Klinikum der Johann Wolfgang Goethe-Universität Zentrum der Inneren Medizin-Infektiologie Theodor-Stern-Kai 7 D-60590 Frankfurt/Main Germany Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126 Journal Volume Volume 26 Journal Issue Volume 26, Number 4 / July, 1998 (Source: Infection) Infection journals http://www.medworm.com/rss/comments.php?id=1832532 Thu, 25 Sep 2008 07:39:41 +0100 1832532 http://www.medworm.com/index.php?rid=1832531&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F187r0547x6762565%2F Content Type Journal ArticleCategory CorrespondenceDOI 10.1007/BF02962379Authors M. Arvand, Freie Universität Berlin Institut für Infektionsmedizin, Universitätsklinikum Benjamin Franklin Hindenburgdamm 27 D-12203 Berlin GermanyM. E. A. Mielke, Freie Universität Berlin Institut für Infektionsmedizin, Universitätsklinikum Benjamin Franklin Hindenburgdamm 27 D-12203 Berlin GermanyT. Regnath, Freie Universität Berlin Institut für Infektionsmedizin, Universitätsklinikum Benjamin Franklin Hindenburgdamm 27 D-12203 Berlin GermanyH. Hahn, Freie Universität Berlin Institut für Infektionsmedizin, Universitätsklinikum Benjamin Franklin Hindenburgdamm 27 D-12203 Berlin GermanyT. Weinke, Klinikum Ernst von Bergmann Medizinische Klinik Charlottenstr. 72 D-14467 Potsdam Germany Jo... Infection journals http://www.medworm.com/rss/comments.php?id=1832531 Thu, 25 Sep 2008 07:39:41 +0100 1832531 http://www.medworm.com/index.php?rid=1832530&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr68851155vh75001%2F Content Type Journal ArticleCategory CorrespondenceDOI 10.1007/BF02962381Authors Christine Schellhorn, Pfizer Mack Abt. Medizin Postfach 49 49 D-76032 Karlsruhe Germany Journal InfectionOnline ISSN 1439-0973Print ISSN 0300-8126 Journal Volume Volume 26 Journal Issue Volume 26, Number 4 / July, 1998 (Source: Infection) Infection journals http://www.medworm.com/rss/comments.php?id=1832530 Thu, 25 Sep 2008 07:39:41 +0100 1832530 http://www.medworm.com/index.php?rid=1832533&cid=s_33374_20_f&fid=33374&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg7642qg334347783%2F Content Type Journal ArticleCategory CorrespondenceDOI 10.1007/BF02962377Authors M. Grunke, Universität Erlangen-Nürnberg Medizinische Klinik III Krankenhausstr. 12 D-91054 Erlangen GermanyH. -G. Kraetsch, Universität Erlangen-Nürnberg Medizinische Klinik III Krankenhausstr. 12 D-91054 Erlangen GermanyP. Löw, Universität Erlangen-Nürnberg Medizinische Klinik III Krankenhausstr. 12 D-91054 Erlangen GermanyA. Rascu, Universität Erlangen-Nürnberg Medizinische Klinik III Krankenhausstr. 12 D-91054 Erlangen GermanyJ. R. Kalden, Universität Erlangen-Nürnberg Medizinische Klinik III Krankenhausstr. 12 D-91054 Erlangen GermanyT. Harrer, Universität Erlangen-Nürnberg Medizinische Klinik III Krankenhausstr. 12 D-91054 Erlangen Germany Journal InfectionOnline ISSN 1439-0973Pri... Infection journals http://www.medworm.com/rss/comments.php?id=1832533 Thu, 25 Sep 2008 07:39:40 +0100 1832533