MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Internal and Emergency Medicine' source. Sat, 20 Mar 2010 14:11:16 +0100 http://www.medworm.com/index.php?rid=3375792&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F58581317r65670pu%2F Abstract  The diagnostic approach to a patient with polycythemia has been greatly simplified by the introduction of new genetic testing in addition to traditional tests, such as measurement of red cell mass and serum erythropoietin (Epo) level. Clonal erythrocytosis, which is the diagnostic feature of polycythemia vera (PV), is almost always associated with a JAK2 mutation (JAK2V617F or exon 12). Therefore, in a patient with acquired erythrocytosis, it is reasonable to begin the diagnostic work-up with JAK2 mutation analysis to distinguish PV from secondary erythrocytosis. The clinical course of PV is marked by a high incidence of thrombotic complications that represent the main cause of morbidity and mortality in these patients. Blood hyperviscosity as well as platelet and... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3375792 Tue, 16 Mar 2010 14:52:54 +0100 3375792 http://www.medworm.com/index.php?rid=3371675&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb13x3v93p4558v47%2F Abstract  In acute pulmonary embolism, patients free from circulatory failure usually present a blood gas pattern consistent with respiratory alkalosis. We investigated whether the appearance of arterial base deficit in these patients indicates disease severity and diagnostic delay. Twenty-four consecutive patients with pulmonary embolism were retrospectively evaluated. Twelve patients had arterial base excess ≥0 mmol/L (Group 1), and 12 patients arterial base deficit <0 mmol/L (Group 2). No patient showed signs of circulatory failure. Group 1 was characterized by a mean base excess of 2.2 ± 1.7 mmol/L, while in Group 2, the mean base deficit was −1.9 ± 0.7 mmol/L (p < 0.0001). At 1 week since the embolism, 1... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3371675 Mon, 15 Mar 2010 18:00:05 +0100 3371675 http://www.medworm.com/index.php?rid=3367525&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa3221v3507685152%2F Content Type Journal ArticleCategory EM - Airway ForumDOI 10.1007/s11739-010-0353-1Authors Colleen Birmingham, Beth Israel Deaconess Medical Center Harvard Medical School Department of Emergency Medicine Boston MA USAKevin Ban, Beth Israel Deaconess Medical Center Harvard Medical School Department of Emergency Medicine Boston MA USAPeter Rosen, Beth Israel Deaconess Medical Center Harvard Medical School Department of Emergency Medicine Boston MA USARichard Wolfe, Beth Israel Deaconess Medical Center Harvard Medical School Department of Emergency Medicine Boston MA USADanny Davis, University of California Department of Emergency Medicine San Diego USAJohn Sakles, University of Arizona Department of Emergency Medicine Tucson USAKenny Bramwell, Boise ID USALeon D. Sanchez, Beth Israel Dea... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3367525 Sun, 14 Mar 2010 12:25:24 +0100 3367525 http://www.medworm.com/index.php?rid=3360711&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr66h4t02x7m4416v%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-010-0366-9Authors Ruggero M. Corso, Anaesthesia and Intensive Care Unit Emergency Department Ospedale “G.B. Morgagni-Pierantoni” Viale Forlanini, 34 47100 Forlì ItalyGiorgio Gambale, Anaesthesia and Intensive Care Unit Emergency Department Ospedale “G.B. Morgagni-Pierantoni” Viale Forlanini, 34 47100 Forlì ItalyEmanuele Piraccini, Anaesthesia and Intensive Care Unit Emergency Department Ospedale “G.B. Morgagni-Pierantoni” Viale Forlanini, 34 47100 Forlì ItalyFlavia Petrini, Università “G.D’Annunzio” Anaesthesia and Intensive Care Chieti-Pescara Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3360711 Thu, 11 Mar 2010 02:49:28 +0100 3360711 http://www.medworm.com/index.php?rid=3360712&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F9455164787k712k3%2F Content Type Journal ArticleCategory ErratumDOI 10.1007/s11739-010-0372-yAuthors Ali A. El-Solh, The Veterans Affairs Western New York Healthcare System Medical Research Blg 20 (151) VISN02, 3495 Bailey Avenue Buffalo NY 14215-1199 USAPhilippe Abou Jaoude, Western New York Respiratory, Research Center Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine Buffalo NY USAJahan Porhomayon, State University of New York at Buffalo School of Medicine and Biomedical Sciences and School of Public Health and Health Professions Department of Anesthesia Buffalo NY USA Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3360712 Thu, 11 Mar 2010 02:49:27 +0100 3360712 http://www.medworm.com/index.php?rid=3336631&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp5524q121085701n%2F Content Type Journal ArticleCategory CE - Medical IllustrationDOI 10.1007/s11739-010-0358-9Authors Fabrizio Elia, San Giovanni Bosco Hospital High Dependency Unit Turin ItalyElisa Fiora, San Giovanni Bosco Hospital High Dependency Unit Turin ItalyGiovanna De Filippi, San Giovanni Bosco Hospital High Dependency Unit Turin ItalyGiovanni Ferrari, San Giovanni Bosco Hospital High Dependency Unit Turin ItalyFranco Aprà, San Giovanni Bosco Hospital High Dependency Unit Turin Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3336631 Wed, 03 Mar 2010 08:07:25 +0100 3336631 http://www.medworm.com/index.php?rid=3336632&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F7464n71128r3u062%2F Content Type Journal ArticleCategory IM - EditorialDOI 10.1007/s11739-010-0352-2Authors Licia Polimeni, University of Rome “La Sapienza” Divisione di I Clinica Medica Rome ItalyLudovica Perri, University of Rome “La Sapienza” Divisione di I Clinica Medica Rome ItalyMirella Saliola, University of Rome “La Sapienza” Divisione di I Clinica Medica Rome ItalyStefania Basili, University of Rome “La Sapienza” Divisione di I Clinica Medica Rome ItalyFrancesco Violi, University of Rome “La Sapienza” Divisione di I Clinica Medica Rome Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3336632 Wed, 03 Mar 2010 08:07:23 +0100 3336632 http://www.medworm.com/index.php?rid=3328584&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu684l1x6155u2237%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-010-0364-yAuthors Roberto Santi, Thrombosis Center Dept. Oncohematology Az. Osp. SS. Antonio e Biagio e C.Arrigo, via Venezia 16 15100 Alessandria ItalyLaura Contino, Thrombosis Center Dept. Oncohematology Az. Osp. SS. Antonio e Biagio e C.Arrigo, via Venezia 16 15100 Alessandria ItalySimona Gatto, Thrombosis Center Dept. Oncohematology Az. Osp. SS. Antonio e Biagio e C.Arrigo, via Venezia 16 15100 Alessandria ItalyAlessandro Levis, Thrombosis Center Dept. Oncohematology Az. Osp. SS. Antonio e Biagio e C.Arrigo, via Venezia 16 15100 Alessandria Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3328584 Tue, 02 Mar 2010 10:07:43 +0100 3328584 http://www.medworm.com/index.php?rid=3313030&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj820v596046n0462%2F Abstract  Osteoporosis and vascular disease are commonly found together in elderly people. Several common mechanisms and risk factors have been suggested to contribute to the development of osteoporosis and atherosclerosis. The present cross-sectional study was performed to determine whether the degree of bone turnover is correlated to carotid intima-media thickness (CCA-IMT), as a marker of subclinical atherosclerosis. We selected 50 outpatients (mean age 71.7 ± 12.3), underwent to eco-Doppler evaluation of extracranial carotid tract, without history of calcium and/or vitamin D supplementation, or antireabsorptive therapy. CCA-IMT was measured by high-resolution B-mode ultrasonography. Bone turnover was evaluated by analysing serum levels of C-terminal telopepti... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3313030 Thu, 25 Feb 2010 08:02:29 +0100 3313030 http://www.medworm.com/index.php?rid=3313031&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2n0046721650ggu4%2F Abstract  Inflammation plays a pivotal role in all stages of atherosclerosis from endothelial dysfunction and plaque formation to plaque destabilization and disruption. Inflammatory biomarkers, originally studied to better understand the pathophysiology of atherosclerosis, have generated increasing interest among clinicians, because of their utility in the challenging problems of diagnosis and risk assessment of patients with suspected or proved coronary heart disease. Moreover, in fascinating perspective, they could be used as therapeutic target, counteracting initiation, progression, and development of complications of atherosclerosis. In this review, we will provide an overview of the more promising inflammatory biomarkers, focusing on their utility and limitations in th... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3313031 Thu, 25 Feb 2010 08:02:28 +0100 3313031 http://www.medworm.com/index.php?rid=3304155&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg1645425280u4n17%2F Content Type Journal ArticleCategory CE - Medical IllustrationDOI 10.1007/s11739-010-0365-xAuthors Sandra Savelli, Azienda U.S.L. di Ferrara U.O. di Medicina Interna, Ospedale del Delta Ferrara ItalyMaria Luisa Grata, Azienda U.S.L. di Ferrara U.O. di Medicina Interna, Ospedale del Delta Ferrara ItalyAlfonsina Ricci, Azienda U.S.L. di Ferrara U.O. di Medicina Interna, Ospedale del Delta Ferrara ItalySusanna Gamberini, Azienda U.S.L. di Ferrara U.O. di Medicina Interna, Ospedale del Delta Ferrara ItalyRoberto Manfredini, Azienda U.S.L. di Ferrara U.O. di Medicina Interna, Ospedale del Delta Ferrara Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3304155 Tue, 23 Feb 2010 08:04:08 +0100 3304155 http://www.medworm.com/index.php?rid=3304154&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F18v734374501h7x4%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-010-0357-xAuthors Adriano Alatri, A.O. Istituti Ospitalieri di Cremona Haemostasis and Thrombosis Centre Viale Concordia 1 26100 Cremona ItalyMarina Foramitti, A.O. Istituti Ospitalieri di Cremona Nephrology and Dialysis Division Cremona ItalyOriana Paoletti, A.O. Istituti Ospitalieri di Cremona Haemostasis and Thrombosis Centre Viale Concordia 1 26100 Cremona ItalyAnke Zimmermann, A.O. Istituti Ospitalieri di Cremona Haemostasis and Thrombosis Centre Viale Concordia 1 26100 Cremona ItalySophie Testa, A.O. Istituti Ospitalieri di Cremona Haemostasis and Thrombosis Centre Viale Concordia 1 26100 Cremona Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: In... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3304154 Tue, 23 Feb 2010 08:04:08 +0100 3304154 http://www.medworm.com/index.php?rid=3304156&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F820g05j7607647x4%2F Abstract  For venous thromboembolism (VTE) prevention in the hospitalized medical patient, no head-to-head trials have been performed of unfractionated heparin (UFH) 5,000 U subcutaneously thrice (i.e. q8 h or TID) daily versus twice daily (q12 h or BID). Several meta-analyses have been undertaken in attempts to determine whether one regimen may be more beneficial for safety and efficacy. Currently, not all international guidelines include a recommended frequency for UFH. Delineation of this frequency may be helpful to the practicing clinician. Primary studies (with a modified Jadad score of ≥6 to demonstrate a stronger study design) that compared low molecular weight heparin (LMWH) and UFH, and UFH and placebo were evaluated. Meta-analyses evaluating safet... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3304156 Tue, 23 Feb 2010 08:04:06 +0100 3304156 http://www.medworm.com/index.php?rid=3304157&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F051711710754m777%2F Abstract  The interaction of ADP with its platelet receptor P2Y12 plays a crucial role in platelet activation and thrombogenesis. This article reviews the pharmacology and clinical trials of specific antagonists of P2Y12. Clopidogrel is a thienopyridine with proven antithrombotic efficacy, but it has some important drawbacks: (a) it is a pro-drug that needs to be metabolized to its active metabolite; (b) it has a delayed onset and offset of action and (c) there is high inter-individual variability in pharmacological response. Prasugrel is also a thienopyridine, with faster onset of action and a more uniform inhibition of platelet function compared to clopidogrel, accounting for lower incidence of ischemic events in patients with acute coronary syndromes (ACS) undergoing per... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3304157 Tue, 23 Feb 2010 08:04:05 +0100 3304157 http://www.medworm.com/index.php?rid=3291609&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa7120gp73n257582%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-010-0360-2Authors Marco Biolato, Catholic University of Rome Department of Internal Medicine 8 Largo A. Gemelli 00168 Rome ItalyMassimo Montalto, Catholic University of Rome Department of Internal Medicine 8 Largo A. Gemelli 00168 Rome ItalyAlfonso Sestito, Catholic University of Rome Department of Cardiology Rome ItalyAntonella Gallo, Catholic University of Rome Department of Internal Medicine 8 Largo A. Gemelli 00168 Rome ItalyAntonio Grieco, Catholic University of Rome Department of Internal Medicine 8 Largo A. Gemelli 00168 Rome Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3291609 Fri, 19 Feb 2010 06:44:41 +0100 3291609 http://www.medworm.com/index.php?rid=3291611&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F1v708g333101n815%2F In conclusion, acute infection–inflammation could play a role in facilitating the occurrence of CST in a subgroup with low risk profile for known risk factors. Our findings, if confirmed, could suggest new opportunities for prevention and treatment of CST. Content Type Journal ArticleCategory IM - OriginalDOI 10.1007/s11739-010-0350-4Authors Stefano Del Pace, University of Florence Department of Heart and Vessels, Azienda Ospedaliera-Universitaria Careggi Viale Morgagni 85 50134 Florence ItalyMaria Boddi, University of Florence Department of Heart and Vessels, Azienda Ospedaliera-Universitaria Careggi Viale Morgagni 85 50134 Florence ItalyRaffaele Rasoini, University of Florence Department of Heart and Vessels, Azienda Ospedaliera-Universitaria Careggi Viale Morgagni 85 50134 Fl... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3291611 Fri, 19 Feb 2010 06:44:39 +0100 3291611 http://www.medworm.com/index.php?rid=3291610&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F9x1747243g036l57%2F Abstract  According to principles of clinical trial design, the demonstration of efficacy of a new treatment is based on comparing the response in the treated group with that of a control group receiving placebo or another active treatment. The need for a control group is also recommended by the major international institutions that govern the ethics and the practice of clinical research. Despite these principles and recommendations, inspection of a purposive sample of ongoing clinical trials listed in the NIH registry (http://ClinicalTrials.gov) reveals that as many as one-third of trials are uncontrolled. Since these trials were approved through a formal evaluation by ethics committees, the lack of adequate control was not perceived as a major deficiency in the study desig... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3291610 Fri, 19 Feb 2010 06:44:39 +0100 3291610 http://www.medworm.com/index.php?rid=3291613&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff1m130816w2w2844%2F Abstract  General concepts about medical disasters, public health and triage are outlined. Triage is described in the context of public health emergencies and disaster settings, and the main ethical values at stake in triage are discussed. Possible conflicts between competing values are outlined. Special attention is given to possible conflicts between the protection of individual interests (typical of clinical ethics), and the pursuit of collective interests (typical of public health and triage). Hippocratic ethics is compared to utilitarian ethics and to perspectives that emphasize the principle of justice. Three ethical attitudes are suggested that may contribute to a resolution of competing values: protection of human dignity, precaution and, especially, solidarity. Per... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3291613 Fri, 19 Feb 2010 06:44:37 +0100 3291613 http://www.medworm.com/index.php?rid=3291612&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F8741786631tq0388%2F Abstract  The use of supplemental sodium bicarbonate for the treatment of patients with septic shock and elevated blood lactate levels remains a controversial therapy. We conducted a retrospective study between March 2004 and February 2009 of 36 consecutive patients diagnosed with septic shock who received continuous infusion of bicarbonate therapy. A control group was matched 1:1 for age, site of infection, and predicted mortality by APACHE II. All patients were managed according to standard protocols. The median time until reversal of shock did not achieve statistical significance between the bicarbonate group (44.5 h [95% confidence interval [CI] 34–54] and the control group (55.0 h [95% CI 39–60] (p = 0.09). The median time to liberation of mechan... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3291612 Fri, 19 Feb 2010 06:44:37 +0100 3291612 http://www.medworm.com/index.php?rid=3270477&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg1j33341116mu653%2F Abstract  Combined antiplatelet and anticoagulant therapy has been suggested for those clinical conditions in which conventional antithrombotic regimens have shown suboptimal efficacy, and in patients with indication for both: antiplatelet and anticoagulant therapy. Clinical trials aimed at assessing the clinical benefit of the association with respect to mono-therapy have been conducted in patients with atrial fibrillation, in patients with recent myocardial infarction, and in patients with prosthetic heart valves. Overall, a favorable benefit-risk profile of combined therapy in comparison to anticoagulant alone has been observed in patients with mechanical prosthetic heart valves and in those with coronary artery disease while no clear advantage has been shown in patients... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3270477 Thu, 11 Feb 2010 11:41:18 +0100 3270477 http://www.medworm.com/index.php?rid=3241231&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fhq73x8q41871t560%2F We present here the epidemiologic and mechanistic evidence to support the protective effect of moderate alcohol intake against cardiovascular disease and all-cause mortality. Content Type Journal ArticleCategory IM - ReviewDOI 10.1007/s11739-010-0346-0Authors Augusto Di Castelnuovo, Catholic University “RE ARTU” Research Laboratories, “John Paul II” Centre For High Technology Research and Education in Biomedical Sciences Largo Gemelli 1 86100 Campobasso ItalySimona Costanzo, Catholic University “RE ARTU” Research Laboratories, “John Paul II” Centre For High Technology Research and Education in Biomedical Sciences Largo Gemelli 1 86100 Campobasso ItalyMaria Benedetta Donati, Catholic University “RE ARTU” Research Laboratories, “John Paul II” Centre For High Te... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3241231 Tue, 02 Feb 2010 18:31:46 +0100 3241231 http://www.medworm.com/index.php?rid=3241232&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc3844mu29vk1521l%2F Content Type Journal ArticleCategory CE - Medical IllustrationDOI 10.1007/s11739-010-0347-zAuthors Alfredo Barillari, Southland Hospital Emergency Department Kew Road 9812 Invercargill New ZealandSampsa Kiuru, Southland Hospital Emergency Department Kew Road 9812 Invercargill New Zealand Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3241232 Tue, 02 Feb 2010 07:00:58 +0100 3241232 http://www.medworm.com/index.php?rid=3228970&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F5j132089r8w43740%2F Content Type Journal ArticleCategory CE - Medical IllustrationDOI 10.1007/s11739-009-0340-6Authors Jarone Lee, Columbia College of Physicians and Surgeons St. Luke’s-Roosevelt Hospital Center 1111 Amsterdam Ave New York NY 10025 USASapna Pawa, New York NY USAJoshua Quaas, Columbia College of Physicians and Surgeons St. Luke’s-Roosevelt Hospital Center 1111 Amsterdam Ave New York NY 10025 USAKaushal H. Shah, Columbia College of Physicians and Surgeons St. Luke’s-Roosevelt Hospital Center 1111 Amsterdam Ave New York NY 10025 USA Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3228970 Sat, 30 Jan 2010 18:16:17 +0100 3228970 http://www.medworm.com/index.php?rid=3228971&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fll0137q1w3760764%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0341-5Authors Alberto Sentimentale, II Medical School University La Sapienza, Sant’Andrea Hospital Department of Emergency Medicine Via di Grottarossa 1035-1039 00189 Rome ItalyMarco Matteoli, II Medical School University La Sapienza, Sant’Andrea Hospital Department of Emergency Medicine Via di Grottarossa 1035-1039 00189 Rome ItalyMorena Giovannelli, II Medical School University La Sapienza, Sant’Andrea Hospital Department of Neuroscience Rome ItalyChiara De Dominicis, II Medical School University La Sapienza, Sant’Andrea Hospital Radiodiagnostic Department Rome ItalyMassimiliano Corsino, II Medical School University La Sapienza, Sant’Andrea Hospital Department of Emergency Medicine Via di G... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3228971 Sat, 30 Jan 2010 18:16:14 +0100 3228971 http://www.medworm.com/index.php?rid=3224025&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F91811j6710017056%2F Content Type Journal ArticleCategory Editor's PageDOI 10.1007/s11739-010-0348-yAuthors Domenico Prisco, Università degli Studi di Firenze Editor-in-Chief, Internal and Emergency Medicine, Dipartimento di Area Critica Medico Chirurgica Viale Morgagni 85 50134 Florence Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3224025 Wed, 27 Jan 2010 20:00:17 +0100 3224025 http://www.medworm.com/index.php?rid=3224024&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh740807r01341wj0%2F Abstract  Despite its rarity, infliximab-related hepatitis constitutes a cutting edge and challenging problem. In December 2004, a drug warning was issued by the Food and Drug Administration to alert healthcare professionals to the risk of hepatotoxicity in course of infliximab therapy. Subsequently, several reports of probable infliximab hepatitis have been published and interest is growing in trying to elucidate the impact of these events on clinical practice. After discussing our case report, the main characteristics of infliximab-mediated liver injury are analyzed, coupled with a review of the medical literature. Infliximab seems to provoke both immunomediated and a direct liver injury, but how this latter happens remains unclear. Moreover, infliximab immunomediated liv... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3224024 Wed, 27 Jan 2010 20:00:17 +0100 3224024 http://www.medworm.com/index.php?rid=3195299&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe0321322p8441038%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0343-3Authors Ilaria Faustina Nataloni, Luigi Sacco Hospital Division of Internal Medicine II, Department of Clinical Science Via G.B. Grassi 74 20157 Milan ItalyElisa Ceriani, Luigi Sacco Hospital Division of Internal Medicine II, Department of Clinical Science Via G.B. Grassi 74 20157 Milan ItalyFabrizio Foieni, Luigi Sacco Hospital Division of Internal Medicine II, Department of Clinical Science Via G.B. Grassi 74 20157 Milan ItalyNicola Montano, Luigi Sacco Hospital Division of Internal Medicine II, Department of Clinical Science Via G.B. Grassi 74 20157 Milan ItalyMarco Cicardi, Luigi Sacco Hospital Division of Internal Medicine II, Department of Clinical Science Via G.B. Grassi 74 20157 Milan Ita... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3195299 Tue, 19 Jan 2010 06:46:09 +0100 3195299 http://www.medworm.com/index.php?rid=3190833&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw29214x7v882j7qw%2F In conclusion, the new 5-min rapid urease test is comparable to the Pyloritek test, but the CLO test is significantly less sensitive at early time points. Reading the test results at 1 min may increase false-negative results with decreasing sensitivity. Content Type Journal ArticleCategory IM - OriginalDOI 10.1007/s11739-009-0344-2Authors Dino Vaira, S. Orsola Hospital, University of Bologna Department of Internal Medicine and Gastroenterology Via Massarenti 9 40138 Bologna ItalyLuigi Gatta, Versilia Hospital Lido di Camaiore ItalyChiara Ricci, University of Brescia Gastroenterology Unit Brescia ItalyFederico Perna, S. Orsola Hospital, University of Bologna Department of Internal Medicine and Gastroenterology Via Massarenti 9 40138 Bologna ItalyIlaria Saracino, S. Orsola Hospita... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3190833 Sat, 16 Jan 2010 06:52:41 +0100 3190833 http://www.medworm.com/index.php?rid=3190834&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2v464u18963v7503%2F Content Type Journal ArticleCategory IM - CommentaryDOI 10.1007/s11739-009-0345-1Authors Patrick G. Northup, University of Virginia Division of Gastroenterology and Hepatology JPA and Lee Street, MSB 2142 P.O. Box 800708 Charlottesville VA 22908-0708 USAStephen H. Caldwell, University of Virginia Division of Gastroenterology and Hepatology JPA and Lee Street, MSB 2142 P.O. Box 800708 Charlottesville VA 22908-0708 USA Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3190834 Fri, 15 Jan 2010 18:05:12 +0100 3190834 http://www.medworm.com/index.php?rid=3086430&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F326171522w4303w6%2F Abstract  Following deep vein thrombosis (DVT), one of every two patients will develop postthrombotic syndrome (PTS), which causes remarkable consequences on the socioeconomic level. Residual thrombosis is an important predictor of PTS, and severe early symptoms, old age, obesity, improper anticoagulation, recurrent thrombosis and varicose veins are major risk factors. Diagnosis of PTS is mainly based on the clinical findings for patients with a history of DVT, while in those without it, instrumental diagnosis might help in detecting a previous DVT. Prompt administration of adequate compression elastic stockings (ECS) in patients with symptomatic DVT reduces the frequency of PTS by half. Usually, the management of an established PTS is demanding, and often discouraging. How... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3086430 Thu, 10 Dec 2009 15:24:27 +0100 3086430 http://www.medworm.com/index.php?rid=3080670&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm9555x53023l832v%2F Abstract  Little information is available on acid–base imbalance in uncomplicated ST-elevation myocardial infarction (STEMI) submitted to primary percutaneous intervention (PCI). We therefore assessed acid–base imbalance in 257 consecutive uncomplicated STEMI patients submitted to PCI to determine whether its evaluation could help in identifying patients at higher risk for in-hospital complications (acute pulmonary edema and dysrhythmias). A basic metabolic profile was performed at hospital admission, that is before PCI. After PCI, we measured: creatinine, uric acid and NT-pro BNP and serum electrolytes. Peak troponin I was also considered. Acidemia was present in 11 patients (4.2%), HCO3 < 22 in 62 (24.1%). Base excess < −3 was detectable in ... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3080670 Wed, 09 Dec 2009 06:51:15 +0100 3080670 http://www.medworm.com/index.php?rid=3080671&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F5w18338535q22515%2F Abstract  In this review, we have analyzed the role of visceral obesity in the occurrence of metabolic syndrome (MetS). MetS is a common metabolic disorder that has been related recently to the increasing prevalence of obesity. The disorder is defined in various ways, but in the near future a new definition(s) should be applicable worldwide. The pathophysiology has been largely attributed, in the past years, to insulin resistance, although several epidemiological and pathophysiological data now indicate visceral obesity as a main factor in the occurrence of all the components of MetS. In view of this, relationships among visceral obesity, free fatty acids, dyslipidemia and insulin resistance have been reported. In addition, the effects of some adipocytokines and other proin... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3080671 Tue, 08 Dec 2009 19:49:35 +0100 3080671 http://www.medworm.com/index.php?rid=3064539&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F8j28p47521848958%2F Content Type Journal ArticleCategory CE - Medical IllustrationDOI 10.1007/s11739-009-0339-zAuthors Emanuele Durante-Mangoni, Second University of Naples Department of Cardiothoracic Sciences Via Leonardo Bianchi snc 80131 Naples ItalyGianantonio Nappi, Second University of Naples Department of Cardiothoracic Sciences Via Leonardo Bianchi snc 80131 Naples Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3064539 Thu, 03 Dec 2009 12:54:05 +0100 3064539 http://www.medworm.com/index.php?rid=3064540&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp553128v77614g36%2F Content Type Journal ArticleCategory CE - Medical IllustrationDOI 10.1007/s11739-009-0337-1Authors Gregoriana Zanini, Section of Cardiology Ospedale di Gavardo Gavardo BresciaAlessandra Pelati, Section of Cardiology Ospedale di Gavardo Gavardo BresciaMonica Bortolotti, Section of Cardiology Ospedale di Gavardo Gavardo BresciaAndrea Tironi, University Study of Brescia Section of 2nd Anatomy Pathology Spedali Civili di Brescia BresciaGian Franco Pasini, Section of Cardiology Ospedale di Gavardo Gavardo Brescia Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3064540 Thu, 03 Dec 2009 12:54:02 +0100 3064540 http://www.medworm.com/index.php?rid=3054145&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb7613j2642641412%2F Abstract  Chronic urticaria (CU) is a skin disorder characterized by the recurrent eruption of short-lived wheals accompanied by redness and itching for at least 6 weeks. The wheals can be associated with angioedema. CU is considered an autoimmune disease in about 50% of cases with the presence of circulating histamine releasing autoantibodies mainly directed against the high affinity IgE receptor FcεRI on mast cells and basophils or against IgE. In several CU cases regarded as idiopathic; the actual pathophysiological mechanisms are still unknown. Some patients with CU do not respond to antihistamines and require the use of systemic steroids or cyclosporin, which are, however, not always effective. In CU, several investigators have demonstrated the activation of coag... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3054145 Tue, 01 Dec 2009 08:43:27 +0100 3054145 http://www.medworm.com/index.php?rid=3054144&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk7689r71873u5112%2F Abstract  Advances in neuroimaging have modified our knowledge on cerebral vein thrombosis (CVT). This disease is now diagnosed more frequently, and increasing evidence as to what are the most common risk factors and on the natural history of the disease is becoming available. Most patients with CVT have a benign prognosis: only a minority of patients die during the acute phase or in the following months. Most patients surviving CVT recover completely, or have only mild functional or cognitive deficits. Unfractionated or low-molecular weight heparin is widely used as a first-line therapy of CVT, despite the absence of conclusive evidence about the safety and efficacy in this setting. Vitamin K antagonists are usually prescribed for secondary prevention, but the optimal dura... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3054144 Tue, 01 Dec 2009 08:43:27 +0100 3054144 http://www.medworm.com/index.php?rid=3054146&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ftn338812w65060m3%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0334-4Authors Satoshi Nakayama, Mishuku Hospital Department of Gastroenterology Tokyo JapanNaoya Murashima, Mishuku Hospital Department of Gastroenterology Tokyo Japan Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3054146 Tue, 01 Dec 2009 08:43:26 +0100 3054146 http://www.medworm.com/index.php?rid=3041280&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc18171634076820t%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0331-7Authors Aurelio Negro, Santa Maria Nuova Hospital Second Unit of Internal Medicine, Department of Internal Medicine viale Risorgimento, 80 42100 Reggio Emilia ItalyChiara Grasselli, Santa Maria Nuova Hospital Second Unit of Internal Medicine, Department of Internal Medicine viale Risorgimento, 80 42100 Reggio Emilia ItalyPaola Galli, Santa Maria Nuova Hospital Second Unit of Internal Medicine, Department of Internal Medicine viale Risorgimento, 80 42100 Reggio Emilia Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3041280 Wed, 25 Nov 2009 17:03:38 +0100 3041280 http://www.medworm.com/index.php?rid=3041279&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl714268n0r718357%2F Abstract  Right ventricular dysfunction during acute pulmonary embolism (PE) predisposes to hemodynamic instability and cardiogenic shock. Aim of this case–control study was to determine the clinical, historical and diagnostic findings associated with right ventricular dysfunction in patients with acute PE involving the main or segmental pulmonary arteries (central PE) and without hemodynamic instability on admission to the Emergency Department (ED) (non-massive PE). From January 1, 2002 to December 31, 2005, 211 patients with central PE were admitted to the Department of Emergency Medicine of the “Antonio Cardarelli” Hospital (Naples, Italy). One hundred eighteen of them had echocardiographic evidence of right ventricular dysfunction on admission to the ED. A history... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3041279 Wed, 25 Nov 2009 17:03:38 +0100 3041279 http://www.medworm.com/index.php?rid=3041281&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu6082642x2022741%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0335-3Authors Alberto Mazza, Rovigo General Hospital Department of Internal Medicine Rovigo ItalyDomenico Montemurro, Rovigo General Hospital Department of Internal Medicine Rovigo ItalyLuca Zattoni, Rovigo General Hospital Department of Radiological Science Rovigo ItalyDomenico Rubello, Rovigo General Hospital Unit of Nuclear Medicine Rovigo ItalySergio Zamboni, Rovigo General Hospital Department of Internal Medicine Rovigo Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3041281 Wed, 25 Nov 2009 17:03:37 +0100 3041281 http://www.medworm.com/index.php?rid=3009924&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F11h810882j532xtx%2F Content Type Journal ArticleCategory Acknowledgement to RefereesDOI 10.1007/s11739-009-0328-2 Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 Journal Volume Volume 4 Journal Issue Volume 4, Number 6 / December, 2009 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=3009924 Wed, 18 Nov 2009 04:59:15 +0100 3009924 http://www.medworm.com/index.php?rid=2971502&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F0357mn261t658751%2F Abstract  To describe the characteristics of “delayed discharge patients” and the factors associated with “delayed discharges”, we performed a 12-month observational study on patients classified as “delayed discharge patients” admitted to an Academic Internal Medicine ward. We assessed the demographic variables, the number and severity of diseases using the Geriatric Index of Comorbidity (GIC), the cognitive, affective and functional status using, respectively, the Mini Mental Stare Examination, the Geriatric Depression Scale and the Barthel Index. We assessed the total length of stay (T-LHS), the total inappropriate length of stay (T-ILHS), the median length of stays (M-LHS), the median inappropriate length of stay (M-ILHS) and evaluated the factors associated ... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2971502 Fri, 06 Nov 2009 06:48:22 +0100 2971502 http://www.medworm.com/index.php?rid=2968768&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq2344j21723818g6%2F Content Type Journal ArticleCategory CE - Medical IllustrationDOI 10.1007/s11739-009-0326-4Authors Sidhartha Sinha, North Middlesex University Hospital NHS Trust London UKKezia Gaitskell, North Middlesex University Hospital NHS Trust London UKRudy Borgstein, North Middlesex University Hospital NHS Trust London UKRomi Navaratnam, North Middlesex University Hospital NHS Trust London UK Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2968768 Thu, 05 Nov 2009 07:45:31 +0100 2968768 http://www.medworm.com/index.php?rid=2968769&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fgn648j653207857k%2F In conclusion, our model shows that, when administered for extended prophylaxis of VTE following MOS, fondaparinux is more effective and cost saving than enoxaparin. Content Type Journal ArticleCategory IM - OriginalDOI 10.1007/s11739-009-0324-6Authors Stefano Capri, Cattaneo-LIUC University Institute of Economics Castellanza ItalyWalter Ageno, University of Insubria Department of Clinical Medicine Varese ItalyDavide Imberti, Hospital of Piacenza Emergency Department, Thrombosis Center Piacenza ItalyGualtiero Palareti, University Hospital Department of Angiology and Blood Coagulation “Marino Golinelli” Bologna ItalyFranco Piovella, Fondazione IRCCS Policlinico “San Matteo” Angiology and Thromboembolic Disease Unit Pavia ItalyGianluigi Scannapieco, Azienda ULSS 9 Treviso Italy... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2968769 Thu, 05 Nov 2009 07:45:29 +0100 2968769 http://www.medworm.com/index.php?rid=2964806&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu3213503760428m2%2F Content Type Journal ArticleCategory CE - Cochrane's CornerDOI 10.1007/s11739-009-0323-7Authors Rita Banzi, Italian Cochrane Centre, Mario Negri Institute for Pharmacological Research Via La Masa, 19 20156 Milan ItalyLorenzo Moja, Italian Cochrane Centre, Mario Negri Institute for Pharmacological Research Via La Masa, 19 20156 Milan ItalyAlessandro Liberati, Italian Cochrane Centre, Mario Negri Institute for Pharmacological Research Via La Masa, 19 20156 Milan ItalyGian Franco Gensini, University of Florence Department of Critical Care Medicine and Surgery Florence ItalyRoberto Gusinu, DAI Cardiologico e dei Vasi, Azienda Ospedaliero-Universitaria Careggi Florence ItalyAndrea A. Conti, University of Florence Department of Critical Care Medicine and Surgery Florence Italy Journal... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2964806 Tue, 03 Nov 2009 22:12:48 +0100 2964806 http://www.medworm.com/index.php?rid=2952110&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F723tu4887j627m81%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0317-5Authors Rino Frizzelli, Bozzolo Hospital Multifunctional Rehabilitation Viale 25 Aprile n. 71 46012 Bozzolo (MN) ItalyOrnella Tortelli, Bozzolo Hospital Multifunctional Rehabilitation Viale 25 Aprile n. 71 46012 Bozzolo (MN) ItalyVincenzo Di Comite, Bozzolo Hospital Multifunctional Rehabilitation Viale 25 Aprile n. 71 46012 Bozzolo (MN) ItalyRedenta Ghirardi, Bozzolo Hospital Multifunctional Rehabilitation Viale 25 Aprile n. 71 46012 Bozzolo (MN) ItalyClaudio Pinzi, Bozzolo Hospital Multifunctional Rehabilitation Viale 25 Aprile n. 71 46012 Bozzolo (MN) ItalyCleante Scarduelli, Bozzolo Hospital Multifunctional Rehabilitation Viale 25 Aprile n. 71 46012 Bozzolo (MN) Italy Journal Internal a... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2952110 Sat, 31 Oct 2009 10:52:44 +0100 2952110 http://www.medworm.com/index.php?rid=2947921&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb8765n82536v4l43%2F Content Type Journal ArticleCategory IM - CommentaryDOI 10.1007/s11739-009-0327-3Authors Giancarlo Agnelli, Università di Perugia Medicina Interna e Cardiovascolare-Stroke Unit, Dipartimento di Medicina Interna Via G. Dottori 1 06129 Perugia ItalyCecilia Becattini, Università di Perugia Medicina Interna e Cardiovascolare-Stroke Unit, Dipartimento di Medicina Interna Via G. Dottori 1 06129 Perugia Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2947921 Fri, 30 Oct 2009 07:48:24 +0100 2947921 http://www.medworm.com/index.php?rid=2853409&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F737u45w18204xhn6%2F Abstract  The classic myeloproliferative neoplasms (MPNs) include polycythemia vera and essential thrombocythemia; their molecular basis has been described only recently with the demonstration of recurrent mutations in JAK2 or MPL. While life expectancy may not be significantly shortened, arterial and venous thrombosis constitute the major causes of morbidity and mortality, together with disease evolution to myelofibrosis or transformation to acute leukemia. Therapy is currently aimed at reducing the rate of thrombosis without increasing the risk of hematologic transformation by inappropriate exposure to cytotoxic drugs. Nevertheless, the mechanism(s) finally responsible for the increased thrombotic tendency have not been clearly elucidated, although risk factors for thrombo... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2853409 Wed, 30 Sep 2009 06:27:47 +0100 2853409 http://www.medworm.com/index.php?rid=2848315&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp6164631872327r2%2F Content Type Journal ArticleCategory IM - Case RecordDOI 10.1007/s11739-009-0318-4Authors Antonella Marcoccia, UOD ANGIOLOGIA, Ospedale Sandro Pertini, Via Dei Monti Tiburtini 00157 Rome ItalyMarco Di Tola, Università Sapienza di Roma Dipartimento di Scienze Cliniche, Policlinico U. I Rome ItalyFrancesca Paris, Università Sapienza di Roma Dipartimento di Scienze Cliniche, Policlinico U. I Rome ItalyGiuseppe Donato, Università Sapienza di Roma Dipartimento Medicina Clinica, Policlinico U. I Rome ItalyValerio Libanori, Università Sapienza di Roma Dipartimento di Scienze Cliniche, Policlinico U. I Rome ItalyAntonio Picarelli, Università Sapienza di Roma Dipartimento di Scienze Cliniche, Policlinico U. I Rome Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Pri... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2848315 Tue, 29 Sep 2009 07:33:37 +0100 2848315 http://www.medworm.com/index.php?rid=2848314&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp8hm378325821176%2F Content Type Journal ArticleCategory CE - The Cutting Edge: Research UpdateDOI 10.1007/s11739-009-0315-7Authors Beatrice Dilaghi, Azienda Ospedaliero-Universitaria Careggi Department of Emergency Medicine Viale Morgagni 85 50134 Florence ItalyPietro Amedeo Modesti, University of Florence and Don Carlo Gnocchi Foundation, IRCCS Florence Department of Critical Care Medicine and Surgery Florence ItalyAndrea Alberto Conti, University of Florence and Don Carlo Gnocchi Foundation, IRCCS Florence Department of Critical Care Medicine and Surgery Florence ItalyCarlo Nozzoli, Azienda Ospedaliero-Universitaria Careggi General Medicine Unit Florence Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2848314 Tue, 29 Sep 2009 07:33:37 +0100 2848314 http://www.medworm.com/index.php?rid=2848317&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F4p4r85p302447606%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0307-7Authors Daniela Colomba, Università degli Studi di Palermo Dipartimento Biomedico di Medicina Interna e Specialistica AOU Policlinico “P. Giaccone” Piazza delle Cliniche no 2 90127 Palermo ItalyDomenico Di Raimondo, Università degli Studi di Palermo Dipartimento Biomedico di Medicina Interna e Specialistica AOU Policlinico “P. Giaccone” Piazza delle Cliniche no 2 90127 Palermo ItalyLuciana Marino, Università degli Studi di Palermo Dipartimento Biomedico di Medicina Interna e Specialistica AOU Policlinico “P. Giaccone” Piazza delle Cliniche no 2 90127 Palermo ItalyRita Marrone, Università degli Studi di Palermo Dipartimento Biomedico di Medicina Interna e Specialistica AOU Policlin... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2848317 Tue, 29 Sep 2009 01:07:09 +0100 2848317 http://www.medworm.com/index.php?rid=2848316&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc892343h316805j2%2F Content Type Journal ArticleCategory CE - Medical IllustrationDOI 10.1007/s11739-009-0322-8Authors Sidhartha Sinha, North Middlesex University Hospital NHS Trust London UKArunthathi Pushparajasekaran, North Middlesex University Hospital NHS Trust London UKRudy Borgstein, North Middlesex University Hospital NHS Trust London UKDavid L. Stoker, North Middlesex University Hospital NHS Trust London UK Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2848316 Tue, 29 Sep 2009 01:07:09 +0100 2848316 http://www.medworm.com/index.php?rid=2848318&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk13u726q5v841632%2F In conclusion, a high prevalence of low-titre aPL was found in cancer patients at diagnosis, but no statistical difference in thrombosis-free survival or in overall survival was observed between aPL positive and aPL negative patients. Content Type Journal ArticleCategory IM - OriginalDOI 10.1007/s11739-009-0316-6Authors Mario Bazzan, CMID, Centro Multidisciplinare di Ricerche di Immunopatologia e Documentazione su Malattie Rare, Struttura Complessa a Direzione Universitaria di Immunologia Clinica, Giovanni Bosco Hospital P.zza Donatori di Sangue 3 10154 Turin ItalyBarbara Montaruli, Laboratory Analysis and Oncology Unit, POEV Turin ItalyAntonella Vaccarino, Cellini Hospital Unit of Haematology and Thrombotic Diseases Turin ItalyGianni Fornari, Laboratory Analysis and Oncology Unit, ... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2848318 Tue, 29 Sep 2009 01:07:08 +0100 2848318 http://www.medworm.com/index.php?rid=2848319&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft55m34n82w334236%2F Abstract  Upper extremities deep venous thrombosis (UEDVT) is a rare condition. According to the literature, approximately 4–10% of all cases of venous thrombosis may involve the subclavian, axillary or brachial veins. In the last few decades, the incidence of UEDVT has increased because of more frequent use of central venous catheters (CVCs) and cardiac pacemaker implantation. In addition, another common risk factor for UEDVT is cancer. UEDVT is classified as primary, approximately one-third of cases, which refers either to effort thrombosis or idiopathic UEDVT, or secondary, due to the presence of overt predisposing causes. The onset of UEDVT is usually characterized by arm swelling and pain, but may also be completely asymptomatic especially in patients with a long-ter... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2848319 Tue, 29 Sep 2009 01:07:07 +0100 2848319 http://www.medworm.com/index.php?rid=2835117&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn537116627t40l2t%2F Content Type Journal ArticleCategory ErratumDOI 10.1007/s11739-009-0308-6Authors Chiara Busti, University of Perugia Division of Internal and Cardiovascular Medicine, Department of Internal Medicine Via E. dal Pozzo 06126 Perugia ItalyEmanuela Falcinelli, University of Perugia Division of Internal and Cardiovascular Medicine, Department of Internal Medicine Via E. dal Pozzo 06126 Perugia ItalyStefania Momi, University of Perugia Division of Internal and Cardiovascular Medicine, Department of Internal Medicine Via E. dal Pozzo 06126 Perugia ItalyPaolo Gresele, University of Perugia Division of Internal and Cardiovascular Medicine, Department of Internal Medicine Via E. dal Pozzo 06126 Perugia Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2835117 Thu, 24 Sep 2009 05:50:33 +0100 2835117 http://www.medworm.com/index.php?rid=2835118&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe76818566mx37463%2F Content Type Journal ArticleCategory IM - CommentaryDOI 10.1007/s11739-009-0321-9Authors Massimo Miniati, Università degli Studi di Firenze Dipartimento di Area Critica Medico Chirurgica Viale Morgagni 85 50134 Florence Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2835118 Thu, 24 Sep 2009 05:50:32 +0100 2835118 http://www.medworm.com/index.php?rid=2835119&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm76g431651026hlv%2F This study is limited by its analysis of a single large institution and a limited set of diagnoses. Content Type Journal ArticleCategory EM - OriginalDOI 10.1007/s11739-009-0313-9Authors Peter Smulowitz, Beth Israel Deaconess Medical Center Department of Emergency Medicine, WCC2 Boston MA 02215 USABruce E. Landon, Harvard Medical School Department of Medicine and Health Care Policy Boston MA USALaura Burke, Beth Israel Deaconess Medical Center Department of Emergency Medicine, WCC2 Boston MA 02215 USAChristopher Baugh, Brigham and Women’s Hospital and Massachusetts General Hospital Department of Emergency Medicine Boston MA USAHeather Gunn, Harvard Medical School Boston MA USARobert Lipton, Beth Israel Deaconess Medical Center Department of Emergency Medicine, WCC2 Boston MA 02215 U... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2835119 Thu, 24 Sep 2009 05:50:31 +0100 2835119 http://www.medworm.com/index.php?rid=2810867&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ffjmr0l422722686m%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0306-8Authors Lorena Duca, University of Milan Department of Internal Medicine, Maggiore Policlinico, Mangiagalli and Regina Elena Foundation IRCCS Milan ItalyPaola Delbini, University of Milan Department of Internal Medicine, Maggiore Policlinico, Mangiagalli and Regina Elena Foundation IRCCS Milan ItalyIsabella Nava, University of Milan Department of Internal Medicine, Maggiore Policlinico, Mangiagalli and Regina Elena Foundation IRCCS Milan ItalyMaria Domenica Cappellini, University of Milan Department of Internal Medicine, Maggiore Policlinico, Mangiagalli and Regina Elena Foundation IRCCS Milan ItalyAnna Meo, University of Messina Department of Pediatrics “G.Martino” Policlinico, Faculty of Me... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2810867 Tue, 15 Sep 2009 21:56:41 +0100 2810867 http://www.medworm.com/index.php?rid=2810866&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F7333k3q634536720%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0305-9Authors Micaela La Regina, Presidio Ospedaliero Unico del Levante Ligure La Spezia I, via V. Veneto 139 19124 La Spezia ItalyMaria Cristina Pierantoni, Presidio Ospedaliero Unico del Levante Ligure La Spezia I, via V. Veneto 139 19124 La Spezia ItalyMassimo Ratti, La Spezia I ItalyFrancesco Orlandini, Presidio Ospedaliero Unico del Levante Ligure La Spezia I, via V. Veneto 139 19124 La Spezia Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2810866 Tue, 15 Sep 2009 21:56:41 +0100 2810866 http://www.medworm.com/index.php?rid=2810869&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw0687731h3613866%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0310-zAuthors Giorgio Costantino, University of Milan Division of Internal Medicine II, L. Sacco Hospital Via GB Grassi 74 20157 Milan ItalyAnna Maria Rusconi, University of Milan Division of Internal Medicine II, L. Sacco Hospital Via GB Grassi 74 20157 Milan ItalyStefano Guzzetti, University of Milan Division of Internal Medicine II, L. Sacco Hospital Via GB Grassi 74 20157 Milan ItalyNicola Montano, University of Milan Division of Internal Medicine II, L. Sacco Hospital Via GB Grassi 74 20157 Milan Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2810869 Tue, 15 Sep 2009 21:56:40 +0100 2810869 http://www.medworm.com/index.php?rid=2810868&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw802kmg045472t10%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0311-yAuthors Mark D. Huffman, Northwestern University Division of Cardiology 676 North St. Clair St., Suite #600 Chicago IL 60611 USASamuel R. Kaufman, University of Michigan Health System Department of Internal Medicine Ann Arbor MI USASanjay Saint, University of Michigan Health System Department of Internal Medicine Ann Arbor MI USA Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2810868 Tue, 15 Sep 2009 21:56:40 +0100 2810868 http://www.medworm.com/index.php?rid=2810870&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm748817lm8315g76%2F Content Type Journal ArticleCategory CE - Medical IllustrationDOI 10.1007/s11739-009-0309-5Authors Alessio Currò, Istituto Nazionale di Ricovero e Cura per Anziani (INRCA) Cosenza ItalyAlessandro Lauro, Istituto Nazionale di Ricovero e Cura per Anziani (INRCA) Cosenza ItalyRaffaella Gallo, Istituto Nazionale di Ricovero e Cura per Anziani (INRCA) Cosenza ItalyAndrea Corsonello, Istituto Nazionale di Ricovero e Cura per Anziani (INRCA) Cosenza Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2810870 Tue, 15 Sep 2009 21:56:39 +0100 2810870 http://www.medworm.com/index.php?rid=2810872&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl84207647820643h%2F Abstract  Direct thrombin inhibitors (DTIs) are a class of anticoagulants that bind selectively to thrombin and block its interaction with its substrates. Dabigatran etexilate and AZD0837, the new generation of DTIs, are now under intense development, and are potentially of great interest for internists. Dabigatran etexilate is a potent, non-peptidic small molecule that specifically and reversibly inhibits both free and clot-bound thrombin by binding to the active site of thrombin molecule. It has been already licensed in the European Union and in Canada for the prevention of VTE in patients undergoing hip- and knee-replacement surgery. Ongoing trials are evaluating its efficacy and safety for the treatment of deep venous thrombosis and pulmonary embolism, primary and secon... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2810872 Tue, 15 Sep 2009 21:56:38 +0100 2810872 http://www.medworm.com/index.php?rid=2810871&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv601rt605426n71w%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0312-xAuthors Luca Cacciotti, Madre Giuseppina Vannini Hospital Cardiology Unit Via di Acqua Bullicante 4 00177 Rome ItalyGiovanni S. Camastra, Madre Giuseppina Vannini Hospital Cardiology Unit Via di Acqua Bullicante 4 00177 Rome ItalyGerardo Ansalone, Madre Giuseppina Vannini Hospital Cardiology Unit Via di Acqua Bullicante 4 00177 Rome Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2810871 Tue, 15 Sep 2009 21:56:38 +0100 2810871 http://www.medworm.com/index.php?rid=2767313&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F92x1xq1432125436%2F Abstract  The receptor for advanced glycation end-products (RAGE) and its ligands are intimately involved in the pathobiology of a wide range of diseases that share common features, such as enhanced oxidative stress, immune/inflammatory responses, and altered cell functions. Soluble forms of RAGE (sRAGE), including the splice variant endogenous secretory (es)RAGE, have been found circulating in plasma and tissues. Experimental data suggest that these isoforms may neutralize the ligand-mediated damage by acting as a decoy. Moreover, evidence is mounting to support a role for both sRAGE and esRAGE as biomarkers or endogenous protection factors against RAGE-mediated pathogenesis. In this review, we will focus on clinical and therapeutical implications arising from studies inve... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2767313 Thu, 03 Sep 2009 06:13:37 +0100 2767313 http://www.medworm.com/index.php?rid=2767314&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F17m6148m58077767%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0301-0Authors Franca Dipaola, A.O. “Istituti Clinici di Perfezionamento” U.O. Medicina Interna Viale Matteotti, 83 20099 Sesto San Giovanni Milan ItalyAndrea Galli, Ospedale “Civile di Vimercate” Medicina Interna Vimercate Milan ItalyCarlo Selmi, IRCCS Istituto Clinico Humanitas, Rozzano, Università di Milano Dipartimento Medicina Interna Milan ItalyRaffaello Furlan, Ospedale “Bolognini”, Università di Milano Medicina Generale Seriate Bergamo Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2767314 Thu, 03 Sep 2009 06:13:36 +0100 2767314 http://www.medworm.com/index.php?rid=2744987&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F62x30n574386636x%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0303-yAuthors Petronella Johanna Van den Berg, St. Elisabeth Hospital Department of Neurology Tilburg The NetherlandsPeter J. Bijlstra, St. Elisabeth Hospital Department of Intensive Care Hilvarenbeekseweg 60 5022 GC Tilburg The NetherlandsGeert J. F. Brekelmans, St. Elisabeth Hospital Department of Neurology Tilburg The Netherlands Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2744987 Fri, 28 Aug 2009 15:00:21 +0100 2744987 http://www.medworm.com/index.php?rid=2744986&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe1268270r9046623%2F Content Type Journal ArticleCategory IM - Case RecordDOI 10.1007/s11739-009-0304-xAuthors Francesco Paneni, University of Rome “La Sapienza” Cardiology Department, II Faculty of Medicine, S. Andrea Hospital Rome ItalyErika Pagannone, University of Rome “La Sapienza” Cardiology Department, II Faculty of Medicine, S. Andrea Hospital Rome ItalyAngela Gurgo, University of Rome “La Sapienza” Cardiology Department, II Faculty of Medicine, S. Andrea Hospital Rome ItalySebastiano Sciarretta, University of Rome “La Sapienza” Cardiology Department, II Faculty of Medicine, S. Andrea Hospital Rome ItalyCamillo Autore, University of Rome “La Sapienza” Cardiology Department, II Faculty of Medicine, S. Andrea Hospital Rome ItalyMassimo Volpe, University of Rome “La Sapienza” C... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2744986 Fri, 28 Aug 2009 15:00:21 +0100 2744986 http://www.medworm.com/index.php?rid=2744989&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F5vv7657hl7l11403%2F Content Type Journal ArticleCategory CE - Cochrane's CornerDOI 10.1007/s11739-009-0296-6Authors Gianni Virgili, University of Florence Department of Oto-Neuro-Ophthalmological Surgical Sciences, Eye Clinic V.le Morgagni 85 50134 Florence ItalyAndrea A. Conti, University of Florence Department of Critical Care Medicine and Surgery Florence ItalyLorenzo Moja, Mario Negri Institute for Pharmacological Research Italian Cochrane Centre Milan ItalyGian Franco Gensini, University of Florence and Azienda Ospedaliero-Universitaria Careggi Department of Critical Care Medicine and Surgery Florence ItalyRoberto Gusinu, DAI Cardiologico e dei Vasi Azienda Ospedaliero, Universitaria Careggi Florence Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2744989 Fri, 28 Aug 2009 15:00:20 +0100 2744989 http://www.medworm.com/index.php?rid=2744988&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm54325475315k150%2F Abstract  Chronic liver disease is characterized by a global hemostatic defect including platelet–vessel wall interaction (primary hemostasis), coagulation and fibrinolysis that may cause abnormalities of the relevant laboratory tests. The causal relationship between abnormal tests and bleeding has been widely accepted, despite the fact that abnormal tests are poorly associated with the timing and incidence of actual bleeding. In this article, we review recent evidence from the literature that disputes the above paradigm, and opens new venues for laboratory/clinical research and patient management in this field. Content Type Journal ArticleCategory IM - ReviewDOI 10.1007/s11739-009-0302-zAuthors Armando Tripodi, University Medical School and IRCCS Ospedale Maggiore Pol... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2744988 Fri, 28 Aug 2009 15:00:20 +0100 2744988 http://www.medworm.com/index.php?rid=2739082&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F13jt475w6320m511%2F Content Type Journal ArticleCategory CE - The Cutting Edge: Research UpdateDOI 10.1007/s11739-009-0294-8Authors Andrea Alberto Conti, University of Florence and Don Carlo Gnocchi Foundation, IRCCS Florence Department of Critical Care Medicine and Surgery Viale Morgagni 85 50134 Florence ItalyBeatrice Dilaghi, Azienda Ospedaliero-Universitaria Careggi Department of Emergency Medicine Florence ItalyPietro Amedeo Modesti, University of Florence and Don Carlo Gnocchi Foundation, IRCCS Florence Department of Critical Care Medicine and Surgery Viale Morgagni 85 50134 Florence ItalyCarlo Nozzoli, Azienda Ospedaliero-Universitaria Careggi General Medicine Unit Florence Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency ... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2739082 Wed, 26 Aug 2009 08:46:35 +0100 2739082 http://www.medworm.com/index.php?rid=2735746&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg50r76j165v2q8vk%2F Content Type Journal ArticleCategory IM - CommentaryDOI 10.1007/s11739-009-0299-3Authors Luigi Alberto Pini, University of Modena and Reggio Emilia Headache Centre via del Pozzo, 71 41100 Modena Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2735746 Tue, 25 Aug 2009 16:48:33 +0100 2735746 http://www.medworm.com/index.php?rid=2735747&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F8781ru17w0hth787%2F Abstract  The microcirculation is defined as the smallest vessels where gas and nutrient exchange with tissues takes place. One of its primary functions is to ensure adequate oxygen delivery to meet the oxygen demands of tissue cells. Previous data from clinical and experimental studies and the recent development of new imaging modalities, such as Orthogonal Polarization Spectral videomicroscopy and Sidestream Dark Field imaging, have helped to identify the crucial role that microcirculation plays in sepsis. If not corrected, microcirculatory dysfunction can lead to respiratory distress in tissue cells and subsequent organ failure, even in the absence of global hemodynamic deficiency. In the present review, we will address past and recent developments regarding the role of ... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2735747 Tue, 25 Aug 2009 16:48:32 +0100 2735747 http://www.medworm.com/index.php?rid=2723676&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl452170154w4h261%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0298-4Authors Marco Rossato, University of Padova Endocrine-Metabolic Unit, Clinica Medica 3, Department of Surgical and Medical Sciences Via Ospedale 105 35128 Padua ItalyMartina Paccagnella, University of Padova Endocrine-Metabolic Unit, Clinica Medica 3, Department of Surgical and Medical Sciences Via Ospedale 105 35128 Padua ItalyMarta Burei, University of Padova Nuclear Medicine Unit, Department of Diagnostic Medical Sciences Padua ItalyGiovanni Federspil, University of Padova Endocrine-Metabolic Unit, Clinica Medica 3, Department of Surgical and Medical Sciences Via Ospedale 105 35128 Padua ItalyRoberto Vettor, University of Padova Endocrine-Metabolic Unit, Clinica Medica 3, Department of Surgica... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2723676 Fri, 21 Aug 2009 17:07:24 +0100 2723676 http://www.medworm.com/index.php?rid=2723677&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2x1185873523564k%2F Abstract  Venous thromboembolism (VTE), which includes deep vein thrombosis and pulmonary embolism, is a major cause of morbidity and mortality in patients undergoing major orthopedic surgery. Routine thromboprophylaxis has been the standard of care over the last 20 years. Currently available options for the prevention of VTE in major orthopedic surgery include low molecular weight heparins, vitamin K antagonists, and, more recently, the synthetic pentasaccharide fondaparinux. Although effective, all these drugs have several limitations and new oral antithrombotics offering predictable, effective and safe anticoagulation are strongly needed. This overview focuses on the most advanced oral direct inhibitors to factor Xa rivaroxaban, apixaban, LY517717 and YM150; specifically... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2723677 Thu, 20 Aug 2009 19:24:23 +0100 2723677 http://www.medworm.com/index.php?rid=2679908&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F1485n886834k1487%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0292-xAuthors Federico Lussana, Università di Milano Divisione di Medicina Generale III, Dipartimento di Medicina, Chirurgia e Odontoiatria, Azienda Ospedaliera San Paolo Via A. di Rudinì, 8 20142 Milan ItalyGian Marco Podda, Università di Milano Divisione di Medicina Generale III, Dipartimento di Medicina, Chirurgia e Odontoiatria, Azienda Ospedaliera San Paolo Via A. di Rudinì, 8 20142 Milan ItalyMarco Cattaneo, Università di Milano Divisione di Medicina Generale III, Dipartimento di Medicina, Chirurgia e Odontoiatria, Azienda Ospedaliera San Paolo Via A. di Rudinì, 8 20142 Milan Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and ... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2679908 Tue, 04 Aug 2009 19:51:23 +0100 2679908 http://www.medworm.com/index.php?rid=2669063&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F383156q23g5h3752%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0291-yAuthors Massimo Gallerani, St. Anna Hospital Division of Internal Medicine, Department of Medicine Corso Giovecca 203 44100 Ferrara ItalyMaura Coletti, St. Anna Hospital Division of Internal Medicine, Department of Medicine Corso Giovecca 203 44100 Ferrara ItalyMauro Ferri, University of Ferrara Department of Ophthalmology Ferrara ItalyNicoletta Napolitano, University of Ferrara Department of Ophthalmology Ferrara ItalyBenedetta Boari, St. Anna Hospital Division of Internal Medicine, Department of Medicine Corso Giovecca 203 44100 Ferrara Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2669063 Mon, 03 Aug 2009 18:04:48 +0100 2669063 http://www.medworm.com/index.php?rid=2665150&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft0397241366242ng%2F Abstract  Treatments for chronic hepatitis C (CHC) patients intolerant to pegylated interferons (peg-IFNs) are lacking. Thus, such patients remain at high risk of developing an advanced and decompensated liver disease. Leukocyte IFN-α (Le-IFN-α) seems to possess a safer profile than other natural and recombinant α-interferons, but no information is available for peg-IFN intolerant patients. Accordingly, we evaluated the safety and efficacy of Le-IFN-α in patients intolerant to peg-IFNs. Twenty-five consecutive CHC patients intolerant to peg-IFNs were prospectively enrolled. HCV genotype 1 was present in 80% and cirrhosis in 68% of cases. Thirteen patients (52%) had thrombocytopenia. Le-IFN-α (3 MU three times a week) was administered for 48 weeks plus ribavir... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2665150 Fri, 31 Jul 2009 19:54:30 +0100 2665150 http://www.medworm.com/index.php?rid=2661584&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm013541374340165%2F Content Type Journal ArticleCategory IM - CommentaryDOI 10.1007/s11739-009-0295-7Authors Luigi M. Biasucci, Catholic University Institute of Cardiology Largo Gemelli 8 00168 Rome ItalyGina Biasillo, Catholic University Institute of Cardiology Largo Gemelli 8 00168 Rome ItalyAntonella Stefanelli, Catholic University Institute of Cardiology Largo Gemelli 8 00168 Rome Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2661584 Tue, 28 Jul 2009 18:28:04 +0100 2661584 http://www.medworm.com/index.php?rid=2651504&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fag75m67742316704%2F Content Type Journal ArticleCategory CE - Medical IllustrationDOI 10.1007/s11739-009-0280-1Authors Gaspare Parrinello, University Hospital of Palermo Biomedical Department of Internal and Specialist Medicine Policlinico “Paolo Giaccone” Piazza Delle Cliniche 2 90127 Palermo ItalyDaniele Torres, University Hospital of Palermo Biomedical Department of Internal and Specialist Medicine Policlinico “Paolo Giaccone” Piazza Delle Cliniche 2 90127 Palermo ItalySalvatore Paterna, University Hospital of Palermo Biomedical Department of Internal and Specialist Medicine Policlinico “Paolo Giaccone” Piazza Delle Cliniche 2 90127 Palermo ItalyManuela Mezzero, University Hospital of Palermo Biomedical Department of Internal and Specialist Medicine Policlinico “Paolo Giaccone” Piazza D... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2651504 Mon, 27 Jul 2009 22:43:35 +0100 2651504 http://www.medworm.com/index.php?rid=2651505&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2666pw7365377264%2F Abstract  Essential thrombocythemia (ET) is a clonal myeloproliferative disorder characterized by sustained increase in platelet number and tendency for thromboembolism. A somatic point mutation that causes a constitutive activation of the JAK2 gene is found in one in two ET patients. ET is more common in women, its incidence being 0.6–2.5/100,000 patient/year and the median age at diagnosis is 65–70 years. ET can affect all age groups, including children (0.09 cases/year), and is often diagnosed in the third–fourth decade of life. Rare cases of familial ET have been reported. Miscarriages are 3–4 times more common among women with ET than in the general population, especially in patients carrying JAK2V617F. Microvascular disturbances are typical of ET, but a m... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2651505 Mon, 27 Jul 2009 22:43:28 +0100 2651505 http://www.medworm.com/index.php?rid=2642680&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa753431g165122w6%2F Content Type Journal ArticleCategory CE - Medical IllustrationDOI 10.1007/s11739-009-0288-6Authors Girolamo Catapano Minotti, Fondazione San Raffaele, Cittadella della Carità Taranto ItalyAndrea Corsonello, Istituto Nazionale di Ricovero e Cura per Anziani (INRCA) Viale della Resistenza Pal. Alfa Scala H, Rende 87036 Cosenza ItalyGiovanni Guadalupi, Fondazione San Raffaele, Cittadella della Carità Taranto ItalyRaffaele Antonelli Incalzi, Fondazione San Raffaele, Cittadella della Carità Taranto Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2642680 Sat, 25 Jul 2009 04:27:24 +0100 2642680 http://www.medworm.com/index.php?rid=2642681&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk086534n87341532%2F Content Type Journal ArticleCategory CE - Medical IllustrationDOI 10.1007/s11739-009-0289-5Authors Vincenzo Brianti, Fidenza Hospital Emergency Medicine Fidenza ItalyCorrado Pattacini, Fidenza Hospital 2nd Unit of Internal Medicine Fidenza ItalyGianni Rastelli, Fidenza Hospital Emergency Medicine Fidenza ItalyMario Pini, Fidenza Hospital 2nd Unit of Internal Medicine Fidenza Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2642681 Fri, 24 Jul 2009 23:51:18 +0100 2642681 http://www.medworm.com/index.php?rid=2642682&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F304866j2gl127n82%2F Content Type Journal ArticleCategory CE - Medical IllustrationDOI 10.1007/s11739-009-0286-8Authors Cemil Kavalci, Trakya University Emergency Department, Faculty of Medicine 22030 Edirne TurkeyNezih Dagdeviren, Trakya University Department of Family Medicine, Faculty of Medicine Edirne TurkeyPolat Durukan, Erciyes University Department of Emergency Medicine, Faculty of Medicine Kayseri TurkeyYunsur Çevik, Ataturk Training and Research Hospital Emergency Department Ankara Turkey Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2642682 Fri, 24 Jul 2009 23:51:17 +0100 2642682 http://www.medworm.com/index.php?rid=2642684&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2186405mmu708205%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0287-7Authors Marco Paolo Donadini, University of Insubria Department of Clinical Medicine Varese ItalyFrancesco Dentali, University of Insubria Department of Clinical Medicine Varese ItalyWalter Ageno, University of Insubria Department of Clinical Medicine Varese Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2642684 Fri, 24 Jul 2009 23:51:16 +0100 2642684 http://www.medworm.com/index.php?rid=2642683&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fak0w02w1lg1m10q6%2F Content Type Journal ArticleCategory EM - Morbidity and Mortality ReportDOI 10.1007/s11739-009-0285-9Authors Russell Evan Berger, Beth Israel Deaconess Medical Center Department of Emergency Medicine 1 Deaconess Road Boston MA 02215 USADaniel C. McGillicuddy, Beth Israel Deaconess Medical Center Department of Emergency Medicine 1 Deaconess Road Boston MA 02215 USA Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2642683 Fri, 24 Jul 2009 23:51:16 +0100 2642683 http://www.medworm.com/index.php?rid=2642685&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F1527tl7h22t1v155%2F Abstract  Matrix metalloproteinases (MMPs), a family of enzymes that degrade extracellular matrix, are emerging as important modulators of atherothrombosis. MMPs are produced by inflammatory cells; some of them are also released by activated platelets and play a crucial role in the remodeling processes, leading to atherosclerotic plaque formation, plaque rupture, arterial aneurysm development, and critical limb ischemia. Independent from their matrix degrading activity, MMPs also regulate some cell functions relevant to atherothrombosis, such as platelet activation, neutrophil activation, and vascular reactivity. Plasma levels of some MMPs are increasingly being recognized as a biomarker of atherosclerosis and cardiovascular risk. In peripheral arterial disease, MMPs have b... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2642685 Fri, 24 Jul 2009 23:51:13 +0100 2642685 http://www.medworm.com/index.php?rid=2623273&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F4l0n178rv2k50552%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0282-zAuthors Seyfettin Köklü, Karargahtepe Mahallesi, Kumrulu Sokak, 18/2, Keçiören Ankara TurkeySelcan Gültuna, Dışkapı Yıldırım Beyazit Educational and Research Hospital Department of Gastroenterology Ankara TurkeyÖmer Başar, Dışkapı Yıldırım Beyazit Educational and Research Hospital Department of Gastroenterology Ankara TurkeyIlhami Yuksel, Dışkapı Yıldırım Beyazit Educational and Research Hospital Department of Gastroenterology Ankara TurkeyMurat Oktay, Dışkapı Yıldırım Beyazit Educational and Research Hospital Department of Pathology Ankara Turkey Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency ... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2623273 Sat, 18 Jul 2009 21:14:28 +0100 2623273 http://www.medworm.com/index.php?rid=2623274&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb44535474675m2p3%2F Abstract  Managing oral anticoagulation may be difficult in hemodialysis patients because the antithrombotic effect can be counterbalanced by an increased risk of hemorrhagic complications. There is insufficient evidence to recommend the routine use of warfarin for thrombosis prophylaxis of the vascular access in all patients. If a decision for anticoagulation is made, dosing warfarin to a “therapeutic” level is suggested, although the most appropriate target INR range remains unclear. Many hemodialysis patients with atrial fibrillation have multiple risk factors for stroke and generally benefit from warfarin, with careful and frequent laboratory monitoring. Treatment with standard dose warfarin is also recommended in patients with venous thromboembolism provided that p... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2623274 Sat, 18 Jul 2009 21:14:15 +0100 2623274 http://www.medworm.com/index.php?rid=2592363&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F6162135n353gv445%2F Abstract  Procalcitonin (PCT) is known to be a biological diagnostic marker for severe sepsis, or septic shock in critically ill patients. There are still contrasting data about a role of procalcitonin in patients with acute myocardial infarction or cardiogenic shock, and in those with acute coronary syndromes, that is, non-ST-elevation myocardial infarction or unstable angina. We evaluated plasma levels of procalcitonin and C-reactive protein (CRP) in 52 patients admitted to our intensive cardiac care unit (ICCU): 14 patients with cardiogenic shock (CS) following ST-elevation myocardial infarction (STEMI), 15 patients with uncomplicated ST-elevation myocardial infarction (STEMI), and 24 with non-ST-elevation myocardial infarction or unstable angina (NSTEMI/UA). In all pati... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2592363 Thu, 09 Jul 2009 12:24:14 +0100 2592363 http://www.medworm.com/index.php?rid=2592364&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd8724007321x0145%2F Content Type Journal ArticleCategory CE - Medical IllustrationDOI 10.1007/s11739-009-0279-7Authors Mohamed Bamoshmoosh, Istituto Ricerche Cliniche Fanfani Florence ItalyStefano Del Pace, Cardiologia Generale 1, AOU Careggi Florence ItalyFabio Fanfani, Istituto Ricerche Cliniche Fanfani Florence ItalyGennaro Santoro, Diagnostica ed Interventistica Cardiovascolare, AOU Careggi Florence Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2592364 Thu, 09 Jul 2009 12:24:13 +0100 2592364 http://www.medworm.com/index.php?rid=2592365&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv5112853lwt181x8%2F Content Type Journal ArticleCategory IM - Case RecordDOI 10.1007/s11739-009-0278-8Authors Costantino Caroselli, Azienda Ospedaliera-Istituti Ospitalieri Dipartimento di Emergenza e Accettazione, Ospedale Civile Maggiore Piazzale A. Stefani, 1 37126 Verona ItalyAnna Tomezzoli, Azienda Ospedaliera-Istituti Ospitalieri Unità di Anatomia ed Istologia Patologica, Ospedale Civile Maggiore Piazzale A. Stefani, 1 37126 Verona ItalyCynthia Caroselli, VA New York Harbor Healthcare System New York USADaniele Longo, Azienda Ospedaliera-Istituti Ospitalieri Dipartimento di Emergenza e Accettazione, Ospedale Civile Maggiore Piazzale A. Stefani, 1 37126 Verona ItalyGuglielmo Bruno, Azienda Ospedaliera Sant’Andrea Unità di Allergologia ed Immunologia Clinica, Dipartimento di Medicina Interna, Univ... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2592365 Thu, 09 Jul 2009 12:24:11 +0100 2592365 http://www.medworm.com/index.php?rid=2578168&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft3l40346648u54q3%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0276-xAuthors Angela Beatrice Scardovi, S. Spirito Hospital Department of Cardiology Lungotevere in Sassia 3 00100 Rome ItalyRenata De Maria, CNR Clinical Physiology Institute Milan Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2578168 Mon, 06 Jul 2009 17:07:54 +0100 2578168 http://www.medworm.com/index.php?rid=2557877&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv73367563685h621%2F Content Type Journal ArticleCategory Editor's PageDOI 10.1007/s11739-009-0272-1Authors Domenico Prisco, Università degli Studi di Firenze Editor-in-Chief, Internal and Emergency Medicine, Dipartimento di Area Critica Medico Chirurgica Viale Morgagni 85 50134 Florence Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2557877 Mon, 29 Jun 2009 14:04:55 +0100 2557877 http://www.medworm.com/index.php?rid=2515990&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq653p705u24l221p%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0274-zAuthors Aldo Airoldi, Azienda Ospedaliera Niguarda Ca’ Granda Struttura Complessa di Epatologia e Gastroenterologia Milan ItalyClaudio Zavaglia, Azienda Ospedaliera Niguarda Ca’ Granda Struttura Complessa di Epatologia e Gastroenterologia Milan ItalyFrancesco Vizzutti, Università degli Studi di Firenze Dipartimento di Medicina Interna, Azienda Ospedaliero Universitaria di Careggi (AOUC) Viale G.B. Morgagni, 85 50134 Florence ItalyMarcello Vangeli, Azienda Ospedaliera Niguarda Ca’ Granda Struttura Complessa di Epatologia e Gastroenterologia Milan ItalyGiovambattista Pinzello, Azienda Ospedaliera Niguarda Ca’ Granda Struttura Complessa di Epatologia e Gastroenterologia Milan Italy J... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2515990 Wed, 24 Jun 2009 06:18:30 +0100 2515990 http://www.medworm.com/index.php?rid=2515991&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fyr21256qrqn41241%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0275-yAuthors Bruno Trimarco, Federico II University Dipartimento di Medicina Clinica, Scienze Cardiovascolari ed Immunologiche Via S. Pansini 5, Edificio 2 80131 Naples ItalyAlessandro Bellis, Federico II University Dipartimento di Medicina Clinica, Scienze Cardiovascolari ed Immunologiche Via S. Pansini 5, Edificio 2 80131 Naples Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2515991 Wed, 24 Jun 2009 06:18:29 +0100 2515991 http://www.medworm.com/index.php?rid=2515992&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F75j422t554441t30%2F Abstract  Migraine is a complex, neurovascular disorder in which genetic and environmental factors interact. At present, frontline therapies in the acute treatment of migraine include the use of non-steroidal anti-inflammatory drugs and triptans. Evidence indicates that calcitonin gene-related peptide (CGRP) plays a fundamental role in the mechanism of migraine. CGRP is a strong vasodilatatory neuropeptide that is released from activated trigeminal sensory nerves. The development of CGRP antagonists has also been driven by the fact that triptans are vasoconstrictive and cannot be safely used in patients with cardiovascular risk factors. Olcegepant (BIBN4096) is the first CGRP antagonist for the treatment of migraine that has been tested in clinical trials, but because of it... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2515992 Wed, 24 Jun 2009 06:18:28 +0100 2515992 http://www.medworm.com/index.php?rid=2489227&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk81624g26j870617%2F Abstract  The widespread use of metal stents and drug-eluting stents has shown the extent to which patients with unstable coronary perfusion depend on antiplatelet drugs, and how their risk of late thrombosis depends on the long-term use of agents such as clopidogrel. It has also been shown that the risk of surgical bleeding, if antiplatelet drugs are continued, is lower than that of coronary thrombosis if they are withdrawn. Thus, except for low-risk settings, the practice of withdrawing antiplatelet drugs 5–10 days prior to surgical procedures should be changed. The following suggestions are meant to provide a guideline in this respect. Most of the current surgical procedures may be performed while on low-dose aspirin treatment. Except when bleeding may occur in cl... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2489227 Wed, 17 Jun 2009 09:43:22 +0100 2489227 http://www.medworm.com/index.php?rid=2489228&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft9r1h1pn75l556g2%2F Content Type Journal ArticleCategory IM - CommentaryDOI 10.1007/s11739-009-0271-2Authors Paolo Gresele, University of Perugia Division of Internal and Cardiovascular Medicine, Department of Internal Medicine Via E. dal Pozzo 06126 Perugia Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2489228 Wed, 17 Jun 2009 09:43:21 +0100 2489228 http://www.medworm.com/index.php?rid=2489229&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa745lj270x773522%2F Content Type Journal ArticleCategory EM - Airway ForumDOI 10.1007/s11739-009-0264-1Authors Kathryn Volz, Beth Israel Deaconess Medical Center Department of Emergency Medicine One Deaconess Road, WCC2 Boston MA 02215 USACarlo Rosen, Beth Israel Deaconess Medical Center Department of Emergency Medicine One Deaconess Road, WCC2 Boston MA 02215 USARichard Wolfe, Beth Israel Deaconess Medical Center Department of Emergency Medicine One Deaconess Road, WCC2 Boston MA 02215 USAKevin Ban, Beth Israel Deaconess Medical Center Department of Emergency Medicine One Deaconess Road, WCC2 Boston MA 02215 USAJohn Sakles, University of Arizona Department of Emergency Medicine Tucson AZ USAKenny Bramwell, St. Luke’s Regional Medical Center Emergency Medicine of Idaho Boise ID USADanny Davis, Universit... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2489229 Wed, 17 Jun 2009 09:43:20 +0100 2489229 http://www.medworm.com/index.php?rid=2489230&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F8p16363076p5m74j%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0257-0Authors Maria De Martino, University of Naples “Federico II” Department of Internal Medicine, Cardiology, Heart and Immunological Sciences, Section of Internal Medicine Via S. Pansini no. 5 80127 Naples ItalyLaura Sasso, University of Naples “Federico II” Department of Internal Medicine, Cardiology, Heart and Immunological Sciences, Section of Internal Medicine Via S. Pansini no. 5 80127 Naples ItalyFlora Pirozzi, University of Naples “Federico II” Department of Internal Medicine, Cardiology, Heart and Immunological Sciences, Section of Internal Medicine Via S. Pansini no. 5 80127 Naples ItalyDomenico Bonaduce, University of Naples “Federico II” Department of Internal Medicine, Ca... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2489230 Mon, 15 Jun 2009 07:37:54 +0100 2489230 http://www.medworm.com/index.php?rid=2477777&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fgg8218l2r1x23626%2F Content Type Journal ArticleCategory IM - Physical ExaminationDOI 10.1007/s11739-009-0268-xAuthors Camilla Tozzetti, University of Florence Department of Critical Care Medicine and Surgery Viale Morgagni 85 Florence ItalyChiara Adembri, University of Florence Department of Critical Care Medicine and Surgery Viale Morgagni 85 Florence ItalyPietro Amedeo Modesti, University of Florence Department of Critical Care Medicine and Surgery Viale Morgagni 85 Florence Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2477777 Sat, 13 Jun 2009 08:23:09 +0100 2477777 http://www.medworm.com/index.php?rid=2477778&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj161861500773200%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0270-3Authors Roberto Delsignore, University of Parma Department of Internal Medicine and Biomedical Sciences Via Gramsci 14 43100 Parma ItalyDiego Ardigo, University of Parma Department of Internal Medicine and Biomedical Sciences Via Gramsci 14 43100 Parma Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2477778 Wed, 10 Jun 2009 09:54:15 +0100 2477778 http://www.medworm.com/index.php?rid=2470480&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F6018003343881846%2F Content Type Journal ArticleCategory CE - Cochrane's CornerDOI 10.1007/s11739-009-0267-yAuthors Alessandro Squizzato, University of Insubria Department of Clinical Medicine, U.O. Medicina I, Ospedale di Circolo Viale Borri 57 21100 Varese ItalyLorenzo Moja, Italian Cochrane Center, Mario Negri Institute for Pharmacological Research Milan ItalyGian Franco Gensini, University of Florence and Azienda Ospedaliero-Universitaria Careggi Department of Critical Care Medicine and Surgery Florence ItalyRoberto Gusinu, DAI Cardiologico e dei Vasi Azienda Ospedaliero-Universitaria Careggi Florence ItalyAndrea A. Conti, University of Florence and Don Carlo Gnocchi Foundation and IRCCS Florence Department of Critical Care Medicine and Surgery Florence Italy Journal Internal and Emergency Medi... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2470480 Tue, 09 Jun 2009 16:00:11 +0100 2470480 http://www.medworm.com/index.php?rid=2470482&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F5385xm45vp509224%2F Content Type Journal ArticleCategory CE - The Cutting Edge: Research UpdateDOI 10.1007/s11739-009-0266-zAuthors Andrea Alberto Conti, University of Florence and Don Carlo Gnocchi Foundation, IRCCS Florence Department of Critical Care Medicine and Surgery Viale Morgagni 85 50134 Florence ItalyBeatrice Dilaghi, Azienda Ospedaliero-Universitaria Careggi Department of Emergency Medicine Florence ItalyPietro Amedeo Modesti, University of Florence and Don Carlo Gnocchi Foundation, IRCCS Florence Department of Critical Care Medicine and Surgery Viale Morgagni 85 50134 Florence ItalyCarlo Nozzoli, Azienda Ospedaliero-Universitaria Careggi General Medicine Unit Florence Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency ... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2470482 Tue, 09 Jun 2009 16:00:10 +0100 2470482 http://www.medworm.com/index.php?rid=2470481&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd132t21456p02843%2F Content Type Journal ArticleCategory IM - CommentaryDOI 10.1007/s11739-009-0269-9Authors Filippo Marzot, University of Padua Department of Cardiac Thoracic and Vascular Sciences, Clinical Cardiology, Thrombosis Center, School of Medicine via Giustiniani 2 35128 Padua ItalyVittorio Pengo, University of Padua Department of Cardiac Thoracic and Vascular Sciences, Clinical Cardiology, Thrombosis Center, School of Medicine via Giustiniani 2 35128 Padua Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2470481 Tue, 09 Jun 2009 16:00:10 +0100 2470481 http://www.medworm.com/index.php?rid=2465277&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl5p1qx812664mh66%2F Abstract  Pulmonary arterial hypertension (PAH) is a devastating disease with significant disability and mortality, and it has much higher prevalence than previously thought. During the past 15 years, we have witnessed remarkable advances in our understanding of pathogenesis, in diagnostic process and in the development of disease-specific treatments for PAH. Nowadays, the diagnosis is more clearly defined, non-invasive markers of disease severity can be widely applied, and finally we can adopt evidence-based treatment. Newer drugs availability has resulted in radical change in the management of this disease. The article reviews established approaches to evaluation and treatment of this disorder. Content Type Journal ArticleCategory IM - ReviewDOI 10.1007/s11739-009-0263-... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2465277 Sat, 06 Jun 2009 11:31:49 +0100 2465277 http://www.medworm.com/index.php?rid=2449368&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fug8683246825450l%2F Abstract  The porphyrias are a heterogeneous group of metabolic diseases resulting from a variable catalytic defect of one of the eight enzymes involved in the heme biosynthesis pathway; they are mostly inherited diseases, but in some circumstances the metabolic disturbance may be acquired. The specific patterns of tissue overproduction (and hence accumulation and excretion) of toxic heme precursors, associated with each enzymatic deficiency, are responsible for the characteristic biochemical and clinical features of each of these diseases. Moreover, even in the presence of a specific inherited enzymatic defect, many different environmental factors (such as drugs, calorie restriction, hormones, sunlight exposition, infections, etc.) often play a key role in triggering the c... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2449368 Fri, 29 May 2009 06:56:42 +0100 2449368 http://www.medworm.com/index.php?rid=2437753&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu133w1654086vu5w%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0262-3Authors Massimo Miniati, University of Florence Department of Medical and Surgical Critical Care Viale Morgagni 85 50134 Florence Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2437753 Tue, 26 May 2009 07:38:40 +0100 2437753 http://www.medworm.com/index.php?rid=2437752&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc7g95977413w313g%2F Abstract  Anabolic steroids are widely used for doping, in professional and domestic sports. The mechanism of action is not completely understood. It may differ somewhat depending on the specific molecule due to structural differences that influence the specificity of binding with steroid receptors. When used by athletes in training, they can improve performance to levels that cannot be attained by almost any combination of sophisticated nonchemical support by modern sport science. The severity of the undesired effects of anabolic steroids depends on a variety of factors, from the type and combination of them, the dose and duration of administration, as well as the gender of the person taking the drug. Younger individuals and women show greater effects caused by anabolic st... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2437752 Tue, 26 May 2009 07:38:40 +0100 2437752 http://www.medworm.com/index.php?rid=2425087&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd5h70485r8r67437%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0259-yAuthors Thiti Snabboon, Chulalongkorn University Department of Internal Medicine Bangkok ThailandAmpai Khemkha, Chulalongkorn University Department of Internal Medicine Bangkok ThailandChananya Chaiyaumporn, Chulalongkorn University Department of Internal Medicine Bangkok ThailandDecha Lalitanantpong, Chulalongkorn University Department of Psychiatry Bangkok ThailandVitaya Sridama, Chulalongkorn University Department of Internal Medicine Bangkok Thailand Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2425087 Tue, 19 May 2009 06:08:00 +0100 2425087 http://www.medworm.com/index.php?rid=2418815&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa617684m2xn264t7%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0258-zAuthors Giovanni Zagli, University of Florence Intensive Care Unit, Emergency Department, Careggi Teaching Hospital Viale Morgagni 85 6 50134 Florence ItalyStefano Batacchi, University of Florence Intensive Care Unit, Emergency Department, Careggi Teaching Hospital Viale Morgagni 85 6 50134 Florence ItalyManuela Bonizzoli, University of Florence Intensive Care Unit, Emergency Department, Careggi Teaching Hospital Viale Morgagni 85 6 50134 Florence ItalyAlessandro Di Filippo, University of Florence Intensive Care Unit, Emergency Department, Careggi Teaching Hospital Viale Morgagni 85 6 50134 Florence ItalyAdriano Peris, University of Florence Intensive Care Unit, Emergency Department, Careggi Teac... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2418815 Fri, 15 May 2009 06:11:39 +0100 2418815 http://www.medworm.com/index.php?rid=2418817&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff368jl383656558q%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0256-1Authors Angela Beatrice Scardovi, UOC Cardiologia, Ospedale S. Spirito Lungotevere in Sassia 3 00100 Rome ItalyRenata De Maria, CNR Clinical Phisiology Institute Milan Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 Journal Volume Volume 4 Journal Issue Volume 4, Number 3 / June, 2009 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2418817 Tue, 12 May 2009 06:03:34 +0100 2418817 http://www.medworm.com/index.php?rid=2418816&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fpt3773614r147450%2F Content Type Journal ArticleCategory Editor's PageDOI 10.1007/s11739-009-0254-3Authors Gian Franco Gensini, University of Florence and Azienda Ospedaliero-Universitaria Editor-in-Chief, Internal and Emergency Medicine, Department of Critical Care Medicine and Surgery Careggi, Viale Morgagni 85 50134 Florence Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 Journal Volume Volume 4 Journal Issue Volume 4, Number 3 / June, 2009 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2418816 Tue, 12 May 2009 06:03:34 +0100 2418816 http://www.medworm.com/index.php?rid=2391778&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm07725v523708816%2F Content Type Journal ArticleCategory CE - Medical IllustrationDOI 10.1007/s11739-009-0253-4Authors Manon N. G. J. A. Braat, UMC Utrecht Department of Surgery Postbus 85500 3508 GA Utrecht The NetherlandsWillem E. Hueting, Meander Medisch Centrum Department of Surgery Postbus 1502 3800 BM Amersfoort The NetherlandsEric J. Hazebroek, UMC Utrecht Department of Surgery Postbus 85500 3508 GA Utrecht The Netherlands Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2391778 Tue, 05 May 2009 05:49:48 +0100 2391778 http://www.medworm.com/index.php?rid=2383908&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe617454576404735%2F Abstract  We evaluated the acute effect of the application of positive end-expiratory pressure (PEEP) on LV diastolic function in 10 healthy subjects. We assessed load dependent diastolic function by Doppler examination of transmitral flow and load independent diastolic function by color M-mode propagation velocity of early flow into the LV cavity (Vp). During the application of PEEP in comparison to the baseline, we found a significant reduction of the E wave peak velocity [79 (64–83) vs. 65 (57–72) cm/s; p = 0.028] and a significant reduction in Vp [84 (73–97) vs. 53 (48–66); p = 0.012]. Moreover, we found a significant reduction in left atrial area [15 (13–18) vs. 12 (10–14) cm2; p = 0.018] and right atrial area [12 (11–15) vs. 1... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2383908 Fri, 01 May 2009 06:49:10 +0100 2383908 http://www.medworm.com/index.php?rid=2377839&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F56271600956t2875%2F Content Type Journal ArticleCategory IM - DebateDOI 10.1007/s11739-009-0251-6Authors Massimo Miniati, Università degli Studi di Firenze Dipartimento di Area Critica Medico Chirurgica Viale Morgagni 85 50134 Florence ItalySimonetta Monti, Istituto di Fisiologia Clinica del Consiglio Nazionale delle Ricerche Pisa Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2377839 Tue, 28 Apr 2009 12:57:41 +0100 2377839 http://www.medworm.com/index.php?rid=2366075&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F1441w7g7715025x3%2F Abstract  The Objective of this prospective observational study was to evaluate the applicability of the simplified acute physiology score (SAPS II) in patients admitted to an Emergency Medicine Ward in the Emergency Medicine Ward of a tertiary university hospital. We studied consecutive patients admitted to an Emergency Medicine Ward from the emergency department. The SAPS II was assessed in predicting overall in-hospital mortality in terms of sensitivity, specificity and receiver operating characteristic (ROC) curve. A total of 211 consecutive patients were admitted over a period of 2 months. Median SAPS II score was 28 (range 6–93), with a mean risk of in-hospital mortality of 0.17 (range 0.01–0.97) for the whole population, and an observed mortality of 15%. The area... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2366075 Thu, 23 Apr 2009 08:12:30 +0100 2366075 http://www.medworm.com/index.php?rid=2366076&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg737236671663431%2F Content Type Journal ArticleCategory IM - CommentaryDOI 10.1007/s11739-009-0237-4Authors Francesco Di Costanzo, Azienda Ospedaliera ed Universitaria Careggi Direttore SC di Oncologia Medica Viale Pieraccini, 17 50139 Florence Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2366076 Thu, 23 Apr 2009 08:12:29 +0100 2366076 http://www.medworm.com/index.php?rid=2357825&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy37228q643358208%2F Content Type Journal ArticleCategory IM - DebateDOI 10.1007/s11739-009-0252-5Authors Edwin J. R. van Beek, Carver College of Medicine Department of Radiology C-751 GH, 200 Hawkins Drive Iowa City IA 52242-1077 USA Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2357825 Tue, 21 Apr 2009 04:58:10 +0100 2357825 http://www.medworm.com/index.php?rid=2333224&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fpv6mr5037q3l1522%2F Content Type Journal ArticleCategory IM - Physical ExaminationDOI 10.1007/s11739-009-0242-7Authors Husni Al-Goshae, Hospital of the University of Science and Technology Sana’a YemenMahdy Al-Karewany, Hospital of the University of Science and Technology Sana’a YemenMohamed Bamosmoosh, University of Florence Department of Critical Care Medicine Viale Morgagni 85 50134 Florence ItalyPietro Amedeo Modesti, University of Florence Department of Critical Care Medicine Viale Morgagni 85 50134 Florence Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2333224 Wed, 15 Apr 2009 08:41:23 +0100 2333224 http://www.medworm.com/index.php?rid=2333223&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F0873v677t282k25g%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0249-0Authors Emanuela Rizzioli, Ospedale del Delta, Azienda U.S.L. di Ferrara Modulo di Nefrologia, Unità Operativa di Medicina Interna Ferrara ItalyElena Incasa, Azienda U.S.L. di Ferrara U.O. di Medicina Interna, Ospedale del Delta Ferrara ItalySusanna Gamberini, Azienda U.S.L. di Ferrara U.O. di Medicina Interna, Ospedale del Delta Ferrara ItalyRoberto Manfredini, Università di Ferrara U.O. di Medicina Interna, Ospedale del Delta, Azienda U.S.L. di Ferrara, e Dipartimento di Medicina Clinica e Sperimentale, Sezione di Clinica Medica via Savonarola 9 44100 Ferrara Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2333223 Wed, 15 Apr 2009 08:41:23 +0100 2333223 http://www.medworm.com/index.php?rid=2333225&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn381011586688755%2F Abstract  Chest pain is one of the most common presenting complaints of a cardiac ischemic event. As the presenting complaint often dictates further interventions, it is necessary to identify and stratify the risk of a cardiac ischemic event in cases of chest pain as the primary complaint. The study also aimed to evaluate the actual number of cardiac ischemic events from all cases of complaints of chest pain. The study aimed to evaluate the occurrence of chest pain as an emergency attended by our emergency management service—108 services. During the period of January 1st–December 31st 2007, a total of 9,130 calls with chest pain were attended to, out of which 6,235 (68.3%) were included who were patients above 30 years of age and for whom complete data were availab... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2333225 Wed, 15 Apr 2009 08:41:22 +0100 2333225 http://www.medworm.com/index.php?rid=2333226&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl297q68585377331%2F Content Type Journal ArticleCategory CE - Cochrane's CornerDOI 10.1007/s11739-009-0243-6Authors Gianni Virgili, University of Florence Department of Oto-Neuro-Ophthalmological Surgical Sciences Florence ItalyAndrea A. Conti, University of Florence, and Don Carlo Gnocchi Foundation, IRCCS Department of Critical Care Medicine and Surgery Florence ItalyVittoria Murro, University of Florence Department of Oto-Neuro-Ophthalmological Surgical Sciences Florence ItalyGian Franco Gensini, University of Florence, and Don Carlo Gnocchi Foundation, IRCCS Department of Critical Care Medicine and Surgery Florence ItalyRoberto Gusinu, DAI Cardiologico e dei Vasi, Azienda Ospedaliero-Universitaria Careggi Florence Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2333226 Thu, 09 Apr 2009 07:27:04 +0100 2333226 http://www.medworm.com/index.php?rid=2333227&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk04k3426m4jn6368%2F Content Type Journal ArticleCategory CE - Medical IllustrationDOI 10.1007/s11739-009-0248-1Authors Cemil Kavalci, Trakya University Emergency Department, Faculty of Medicine 22030 Edirne TurkeyYunsur Cevik, Ataturk Training and Research Hospital Emergency Department Ankara TurkeyPolat Durukan, Erciyes University Emergency Department, Faculty of Medicine Kayseri TurkeyOsman Temizoz, Trakya University Radiology Department, Faculty of Medicine Edirne Turkey Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2333227 Thu, 09 Apr 2009 07:27:03 +0100 2333227 http://www.medworm.com/index.php?rid=2333229&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk22356812x48h773%2F Abstract  The aim of this study was to evaluate the accuracy of procalcitonin (PCT) in predicting infective endocarditis (IE). 23 adult patients with IE, 30 patients with sepsis and 30 with tick-borne encephalitis were included in this prospective study. The PCT serum level, C-reactive protein (CRP), total leukocyte, and immature polymorphonuclear (PMN) cell counts were determined on admission, prior to the institution of antibiotic therapy, and compared according to the diagnosis. The median PCT level in patients with IE endocarditis was 0.81 ng/ml, in patients with sepsis it was 43.74 ng/ml, and in the group with viral infection it was 0.25 ng/ml (P < 0.001). The highest PCT level was found in patients with Staphylococcus aureus endocarditis. Th... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2333229 Thu, 09 Apr 2009 07:11:49 +0100 2333229 http://www.medworm.com/index.php?rid=2333228&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F4654415637270q88%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0247-2Authors Marco P. Donadini, University of Insubria Department of Clinical Medicine Varese ItalyAlessandro Squizzato, University of Insubria Department of Clinical Medicine Varese ItalyFrancesco Dentali, University of Insubria Department of Clinical Medicine Varese ItalyWalter Ageno, University of Insubria Department of Clinical Medicine Varese Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2333228 Thu, 09 Apr 2009 07:11:49 +0100 2333228 http://www.medworm.com/index.php?rid=2333230&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq3264g1n23421132%2F Abstract  To analyse the relationship of PAI-1 plasma levels to echographically determined liver steatosis and cardiometabolic risk factors in a randomly selected sample of 254 adult male participants of the Olivetti Heart Study. Accounting for age and ongoing pharmacological treatment, PAI-1 levels were directly (P < 0.005) associated with body mass index (BMI), waist circumference (WC), serum triglyceride (TG), total cholesterol, insulin, homeostasis model assessment index, gamma-glutamyl transpeptidase and peritoneal fat. At multiple linear regression (MLR) analysis, measures of adiposity and TG exerted significant and quantitatively similar effects on PAI-1 levels. A progressive rise in PAI-1 level was detected with increasing degree of steatosis. A stepwise... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2333230 Tue, 07 Apr 2009 05:52:46 +0100 2333230 http://www.medworm.com/index.php?rid=2307309&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc4581664842246j3%2F Content Type Journal ArticleCategory CE - The Cutting Edge: Research UpdateDOI 10.1007/s11739-009-0244-5Authors Andrea Alberto Conti, University of Florence and Don Carlo Gnocchi Foundation, IRCCS Florence Department of Critical Care Medicine and Surgery Viale Morgagni 85 50134 Florence ItalyBeatrice Dilaghi, Azienda Ospedaliero-Universitaria Careggi Department of Emergency Medicine Florence ItalyPietro Amedeo Modesti, University of Florence and Don Carlo Gnocchi Foundation, IRCCS Florence Department of Critical Care Medicine and Surgery Viale Morgagni 85 50134 Florence ItalyCarlo Nozzoli, Azienda Ospedaliero-Universitaria Careggi General Medicine Unit Florence Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency ... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2307309 Tue, 31 Mar 2009 05:52:46 +0100 2307309 http://www.medworm.com/index.php?rid=2307311&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb3q7858n150jm702%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0239-2Authors Gaspare Parrinello, University Hospital of Palermo Heart Failure Unit, Biomedical Department of Internal and Specialist Medicine, Policlinico “Paolo Giaccone” Piazza delle Cliniche 2 90127 Palermo ItalyDaniele Torres, University Hospital of Palermo Heart Failure Unit, Biomedical Department of Internal and Specialist Medicine, Policlinico “Paolo Giaccone” Piazza delle Cliniche 2 90127 Palermo ItalySalvatore Paterna, University Hospital of Palermo Heart Failure Unit, Biomedical Department of Internal and Specialist Medicine, Policlinico “Paolo Giaccone” Piazza delle Cliniche 2 90127 Palermo ItalyGiuseppe Licata, University Hospital of Palermo Heart Failure Unit, Biomedical Depar... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2307311 Tue, 31 Mar 2009 05:52:45 +0100 2307311 http://www.medworm.com/index.php?rid=2307310&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk545t63475022305%2F Content Type Journal ArticleCategory IM - CommentaryDOI 10.1007/s11739-009-0241-8Authors Davide Capodanno, University of Florida College of Medicine-Jacksonville Division of Cardiology 655 West 8th Street Jacksonville FL 32209 USADominick J. Angiolillo, University of Florida College of Medicine-Jacksonville Division of Cardiology 655 West 8th Street Jacksonville FL 32209 USA Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2307310 Tue, 31 Mar 2009 05:52:45 +0100 2307310 http://www.medworm.com/index.php?rid=2287427&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F9277u43547467778%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0238-3Authors Alessandro Squizzato, University of Insubria Department of Clinical Medicine Varese ItalyElisa Manfredi, University of Insubria Department of Clinical Medicine Varese ItalyBregje van Zaane, Academic Medical Center Department of Vascular Medicine Amsterdam The NetherlandsVictor E. Gerdes, Academic Medical Center Department of Vascular Medicine Amsterdam The Netherlands Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2287427 Fri, 20 Mar 2009 10:50:44 +0100 2287427 http://www.medworm.com/index.php?rid=2276881&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh0524u27l3244834%2F Content Type Journal ArticleCategory CE - Medical IllustrationDOI 10.1007/s11739-009-0233-8Authors Cemil Kavalci, Trakya University Emergency Department, Faculty of Medicine Güllapoglu 22030 Edirne TurkeyMehmet İnal, Trakya University Anesthesia Department, Faculty of Medicine 22100 Edirne TurkeyAlkin Colak, Trakya University Anesthesia Department, Faculty of Medicine 22100 Edirne TurkeyPolat Durukan, Erciyes University Emergency Department, Faculty of Medicine Kayseri TurkeyGülsüm Kavalci, Trakya University Anesthesia Department, Faculty of Medicine 22100 Edirne TurkeyYunsur Çevik, Emergency Department, Atatürk Training and Education Hospital 06450 Bilkent Ankara TurkeySibel Güldiken, Trakya University Emergency Department, Faculty of Medicine Güllapoglu 22030 Edirne Turkey ... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2276881 Sat, 14 Mar 2009 13:59:32 +0100 2276881 http://www.medworm.com/index.php?rid=2276882&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F9103976q7r6126q1%2F Content Type Journal ArticleCategory IM - Case RecordDOI 10.1007/s11739-009-0232-9Authors Giuseppe Daniele, Ospedale Cisanello, University of Pisa Section of Diabetes and Metabolic Diseases, Department of Endocrinology and Metabolism Via Paradisa 2 56124 Pisa ItalyCristina Bianchi, Ospedale Cisanello, University of Pisa Section of Diabetes and Metabolic Diseases, Department of Endocrinology and Metabolism Via Paradisa 2 56124 Pisa ItalyGraziano Di Cianni, Ospedale Cisanello, University of Pisa Section of Diabetes and Metabolic Diseases, Department of Endocrinology and Metabolism Via Paradisa 2 56124 Pisa ItalyStefano Del Prato, Ospedale Cisanello, University of Pisa Section of Diabetes and Metabolic Diseases, Department of Endocrinology and Metabolism Via Paradisa 2 56124 Pisa ItalyRob... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2276882 Sat, 14 Mar 2009 13:59:30 +0100 2276882 http://www.medworm.com/index.php?rid=2276883&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F1662x707743q1284%2F Abstract  Atrial fibrillation (AF) is often associated, more or less indirectly, with an inflammatory acute or chronic process. So it is probable that the inflammation could contribute to the genesis and the perpetuation of this dysrhythmia. Phlogistic test indexes in patients (pts) with AF will be positive and have prognostic significance in patients treated with electrical cardioversion with restoration of a sinus rhythm. We evaluated 106 pts affected by AF of recent onset without known cardiovascular disease. We measured the plasma concentration of C-reactive protein (CRP) through a high sensibility method, in addition to routine blood samples. We perfomed an ECG 1 week and a Holter ECG monitoring 1 and 6 months after the electrical cardioversion. The CRP value... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2276883 Sat, 14 Mar 2009 13:59:28 +0100 2276883 http://www.medworm.com/index.php?rid=2263058&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F8108jmlx25u44818%2F Abstract  Diabetic patients have an increased risk for cardiovascular complications with respect to the general population. Micro- and macrovascular complications such as nephropathy, retinopathy, atherosclerosis, and coronary artery disease are usually preceded by endothelial dysfunction, a condition characterized by impaired vasorelaxation resulting from reduced bioavailability of the endothelial mediator nitric oxide (NO). Nitric oxide is among endothelial mediators released by endothelial cells in response to insulin stimulation. Therefore, metabolic abnormalities such as insulin resistance, dyslipidemia, compensatory hyperinsulinemia and overt hyperglycemia may all contribute to impaired NO bioavailability and abnormal vasodilatation in diabetic patients. Each of these... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2263058 Thu, 12 Mar 2009 10:29:17 +0100 2263058 http://www.medworm.com/index.php?rid=2241501&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F34652x8433207121%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0230-yAuthors Damiano Magrì, University of Rome “La Sapienza” Cardiology Department, S. Andrea Hospital Via di Grottarossa, 1035-39 00189 Rome ItalyMassimo Volpe, University of Rome “La Sapienza” Cardiology Department, S. Andrea Hospital Via di Grottarossa, 1035-39 00189 Rome Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2241501 Wed, 04 Mar 2009 10:45:46 +0100 2241501 http://www.medworm.com/index.php?rid=2223144&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F72t17232767t130q%2F In conclusion, Nt-proBNP correlates with PAPs and may be used to exclude preclinical or symptomatic CTPH in patients with previous PE. Prospective studies on a larger population are warranted to confirm our preliminary findings. Content Type Journal ArticleCategory IM - Original ArticleDOI 10.1007/s11739-009-0231-xAuthors Francesco Dentali, University of Insubria Department of Clinical Medicine Varese ItalyMarco Donadini, University of Insubria Department of Clinical Medicine Varese ItalyMonica Gianni, University of Insubria Department of Clinical Medicine Varese ItalyAndrea Bertolini, University of Insubria Department of Clinical Medicine Varese ItalyEva Lonn, McMaster University Division of Cardiology, Department of Medicine Hamilton ON CanadaAchille Venco, University of Insubria D... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2223144 Fri, 27 Feb 2009 10:17:11 +0100 2223144 http://www.medworm.com/index.php?rid=2205430&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F217155l37w32np82%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0229-4Authors Rafał Dąbrowski, Institute of Cardiology II Ischemic Heart Disease Department Spartańska 1 02-637 Warsaw PolandCezary Sosnowski, Institute of Cardiology I Ischemic Heart Disease Department Spartańska 1 02-637 Warsaw PolandEwa Michalak, Institute of Cardiology Department of Adult Congenital Heart Disease Alpejska 42 04-628 Warsaw PolandHanna Szwed, Institute of Cardiology II Ischemic Heart Disease Department Spartańska 1 02-637 Warsaw Poland Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2205430 Thu, 19 Feb 2009 14:21:17 +0100 2205430 http://www.medworm.com/index.php?rid=2205431&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr124w0h67856421n%2F Content Type Journal ArticleCategory IM - Physical ExaminationDOI 10.1007/s11739-009-0224-9Authors Iacopo Bertolozzi, Ospedale di Carrara Cardiologia–Cardiostimolazione Carrara Piazza Sacco e Vanzetti, 1 54033 Carrara ItalyAngelo Pucci, Ospedale di Carrara Cardiologia–Cardiostimolazione Carrara Piazza Sacco e Vanzetti, 1 54033 Carrara ItalyPietro Amedeo Modesti, University of Florence Department of Critical Care Medicine Florence Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2205431 Thu, 19 Feb 2009 14:21:14 +0100 2205431 http://www.medworm.com/index.php?rid=2205432&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh54157u536895005%2F Content Type Journal ArticleCategory IM - Case RecordDOI 10.1007/s11739-009-0228-5Authors Costantino Caroselli, Azienda Ospedaliera-Istituti Ospitalieri Dipartimento di Emergenza e Accettazione, Ospedale Civile Maggiore Verona ItalyAlberto Gabrieli, Azienda Ospedaliera-Istituti Ospitalieri Dipartimento di Emergenza e Accettazione, Ospedale Civile Maggiore Verona ItalyAntonio Pisani, Ospedale “San Benedetto” Servizio di Cardiologia Alatri (Fr) ItalyGuglielmo Bruno, Università di Roma “La Sapienza” Unità di Allergologia ed Immunologia Clinica, Dipartimento di Medicina Interna, II Facoltà di Medicina e Chirurgia, Azienda Ospedaliera “Sant’Andrea” Via di Grottarossa, 1035 00189 Rome Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-04... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2205432 Thu, 19 Feb 2009 14:21:12 +0100 2205432 http://www.medworm.com/index.php?rid=2205433&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F922u1j4v8880l4q2%2F Content Type Journal ArticleCategory IM - Case RecordDOI 10.1007/s11739-009-0227-6Authors Andrea Alberti, Santa Maria della Misericordia Hospital, University of Perugia Stroke Unit, Department of Internal and Cardiovascular Medicine S. Andrea delle Fratte 06156 Perugia ItalyGiancarlo Agnelli, Santa Maria della Misericordia Hospital, University of Perugia Stroke Unit, Department of Internal and Cardiovascular Medicine S. Andrea delle Fratte 06156 Perugia ItalyMohammed Hamam, Santa Maria della Misericordia Hospital Department of Neuroradiology Perugia ItalyStefano Pasquino, Santa Maria della Misericordia Hospital Department of Cardiac Surgery Perugia ItalyPiero Floridi, Santa Maria della Misericordia Hospital Department of Neuroradiology Perugia ItalyTemistocle Ragni, Santa Maria della M... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2205433 Thu, 19 Feb 2009 14:21:10 +0100 2205433 http://www.medworm.com/index.php?rid=2173480&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F40423826n437663u%2F Content Type Journal ArticleCategory CE - The Cutting Edge: Research UpdateDOI 10.1007/s11739-009-0226-7Authors Andrea Alberto Conti, University of Florence and Don Carlo Gnocchi Foundation, IRCCS Florence Department of Critical Care Medicine and Surgery Viale Morgagni 85 50134 Florence ItalyBeatrice Dilaghi, Azienda Ospedaliero-Universitaria Careggi Department of Emergency Medicine Florence ItalyPietro Amedeo Modesti, University of Florence and Don Carlo Gnocchi Foundation, IRCCS Florence Department of Critical Care Medicine and Surgery Viale Morgagni 85 50134 Florence ItalyCarlo Nozzoli, General Medicine Unit, Azienda Ospedaliero-Universitaria Careggi Florence Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2173480 Sat, 07 Feb 2009 10:16:16 +0100 2173480 http://www.medworm.com/index.php?rid=2134918&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy2028312861558rj%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-009-0225-8Authors Filippo Luca Fimognari, Leopoldo Parodi-Delfino Hospital Division of Internal Medicine ASL Roma G, Colleferro Rome ItalyFrancesco Violi, University La Sapienza Division of Internal Medicine H Rome Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2134918 Sat, 24 Jan 2009 13:14:33 +0100 2134918 http://www.medworm.com/index.php?rid=2110866&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F1278k77x43224r00%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-008-0223-2Authors Giovanni Salvatore Camastra, Madre Giuseppina Vannini Hospital Cardiology Unit via di Acqua Bullicante 4 00177 Rome ItalyLuca Cacciotti, Madre Giuseppina Vannini Hospital Cardiology Unit via di Acqua Bullicante 4 00177 Rome ItalyRaffaella Semeraro, Madre Giuseppina Vannini Hospital Cardiology Unit via di Acqua Bullicante 4 00177 Rome ItalyFabio Marconi, Madre Giuseppina Vannini Hospital Radiology Unit Rome ItalyStefano Sbarbati, Madre Giuseppina Vannini Hospital Radiology Unit Rome ItalyMassimiliano Danti, Madre Giuseppina Vannini Hospital Radiology Unit Rome ItalySabino Della Sala, Madre Giuseppina Vannini Hospital Radiology Unit Rome ItalyGerardo Ansalone, Madre Giuseppina Vannini Hospi... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2110866 Thu, 15 Jan 2009 08:36:49 +0100 2110866 http://www.medworm.com/index.php?rid=2095109&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn670643846300156%2F Content Type Journal ArticleCategory ErratumDOI 10.1007/s11739-008-0221-4Authors Daniel C. McGillicuddy, Beth Israel Deaconess Medical Center Department of Emergency Medicine One Deaconess Road, WCC-2 Boston MA 02215 USAAimee Tang, Beth Israel Deaconess Medical Center Boston USALauren Cataldo, Beth Israel Deaconess Medical Center Boston USAJulia Gusev, Harvard Medical School Boston USANathan I. Shapiro, Beth Israel Deaconess Medical Center Department of Emergency Medicine One Deaconess Road, WCC-2 Boston MA 02215 USA Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2095109 Thu, 08 Jan 2009 08:49:42 +0100 2095109 http://www.medworm.com/index.php?rid=2095110&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F674128l576r77p76%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-008-0222-3Authors Laura Andreoli, Spedali Civili and University of Brescia Department of Rheumatology and Clinical Immunology Piazzale Spedali Civili 1 25123 Brescia ItalyAngela Tincani, Spedali Civili and University of Brescia Department of Rheumatology and Clinical Immunology Piazzale Spedali Civili 1 25123 Brescia Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: Internal and Emergency Medicine) Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2095110 Thu, 08 Jan 2009 08:49:40 +0100 2095110 http://www.medworm.com/index.php?rid=2095111&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fdx31v13u3707666n%2F Content Type Journal ArticleCategory CE - Letter to the EditorDOI 10.1007/s11739-008-0219-yAuthors Marco Senzolo, University Hospital of Padua Gastroenterology Section, Department of Surgical and Gastroenterological Sciences Via Giustiniani 2 35136 Padua ItalyCecilia Ferronato, University Hospital of Padua Gastroenterology Section, Department of Surgical and Gastroenterological Sciences Via Giustiniani 2 35136 Padua ItalyPatrizia Burra, University Hospital of Padua Gastroenterology Section, Department of Surgical and Gastroenterological Sciences Via Giustiniani 2 35136 Padua ItalyMaria Teresa Sartori, University of Padua 2nd Chair Internal Medicine, Department of Cardiologic, Thoracic and Vascular Sciences Padua Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366P... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2095111 Thu, 08 Jan 2009 08:49:39 +0100 2095111 http://www.medworm.com/index.php?rid=2095112&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F556137p815282274%2F Abstract  In this paper, data from available studies regarding some contemporary issues on clopidogrel therapy are analyzed. In particular, the following clinical questions have been considered and addressed: (a) Is early clopidogrel treatment needed in patients with acute coronary syndromes treated medically or undergoing percutaneous coronary intervention (PCI)? (b) What is the optimal clopidogrel loading dose in patients undergoing PCI? (c) Is pre-treatment with clopidogrel before PCI needed, or can clopidogrel loading be given in the catheter laboratory before intervention, but after coronary anatomy is known? (d) What is the optimal clopidogrel strategy in patients on chronic clopidogrel therapy undergoing PCI? (e) Does the degree of clopidogrel response influence clin... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2095112 Thu, 08 Jan 2009 08:49:38 +0100 2095112 http://www.medworm.com/index.php?rid=2061671&cid=s_35975_14_f&fid=35975&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg757628156619067%2F Content Type Journal ArticleCategory CE - Cochrane's CornerDOI 10.1007/s11739-008-0216-1Authors Livia Puljak, University of Split School of Medicine Soltanska 2 21000 Split CroatiaLorenzo Moja, Mario Negri Institute for Pharmacological Research Italian Cochrane Center Via La Masa 19 20156 Milan ItalyGian Franco Gensini, University of Florence and Azienda Ospedaliero-Universitaria Careggi Department of Critical Care Medicine and Surgery Florence ItalyRoberto Gusinu, DAI Cardiologico e dei Vasi Azienda Ospedaliero-Universitaria Careggi Florence ItalyAndrea A. Conti, University of Florence and Don Carlo Gnocchi Foundation, IRCCS Department of Critical Care Medicine and Surgery Florence Italy Journal Internal and Emergency MedicineOnline ISSN 1970-9366Print ISSN 1828-0447 (Source: I... Internal and Emergency Medicine journals http://www.medworm.com/rss/comments.php?id=2061671 Sun, 21 Dec 2008 10:26:18 +0100 2061671