MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'International Ophthalmology' source. Wed, 08 Feb 2012 23:31:39 +0100 http://www.medworm.com/index.php?rid=5669122&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl8908h53k8852j2t%2F We report a case of choroidal tuberculoma associated with tuberculosis in a patient with ocular Behçet disease. A 25-year-old female with known ocular Behçet disease contracted tuberculosis 3 months earlier. She had been receiving methotrexate and oral steroids. Funduscopy of the left eye revealed a choroidal tuberculoma located superonasally to the optic disc. Fluorescein angiography showed a central area of hypofluorescence surrounded by a hyperfluorescent zone. Since she was already receiving antituberculosis treatment combined with oral steroids, the same treatment was continued. Diagnosis of the other diseases that may cause uveitis in patients with Behçet disease should not be missed. This is especially important since immunosuppressive drugs, that cause an increased in... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5669122 Mon, 06 Feb 2012 19:36:46 +0100 5669122 http://www.medworm.com/index.php?rid=5661117&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F581605674277hm05%2F Abstract  To report a case of microtrauma-induced recurrent hyphema and secondary glaucoma associated with voluntary chronic acetylsalicylic acid (ASA) use. A 43-year-old male developed advanced glaucoma in his right eye after a two-month follow-up period of recurrent microhyphema, which had been induced by strong eye-rubbing. In spite of topical and systemic antiglaucoma medication, as well as topical corticosteroid and cycloplegic drugs and bed rest under hospitalization, the hyphema and glaucoma were not controlled. His medical history revealed that he had been using ASA for 2 years in order to prevent heart attacks. We asked the patient to stop ASA intake and the hyphema cleared considerably on the third day after discontinuation of the drug. One week after stoppin... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5661117 Thu, 02 Feb 2012 06:54:11 +0100 5661117 http://www.medworm.com/index.php?rid=5650835&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh152743655401733%2F Abstract  Beta-blockers are a well-known prophylactic treatment for migraine; however, treatment by the ocular route has not been widely considered. This case illustrates the resolution of a visual field defect associated with migraine and improvement of symptoms possibly due to administration of a topical beta-blocker. This novel method of treatment especially when visual field defects are present may have a place in the management of migraine. Content Type Journal ArticleCategory Case ReportPages 1-4DOI 10.1007/s10792-012-9516-6Authors Patrick J. T. Chiam, Eye Unit, Stoke Mandeville Hospital, Aylesbury, Buckinghamshire HP21 8AL, UK Journal International OphthalmologyOnline ISSN 1573-2630Print ISSN 0165-5701 (Source: International Ophthalmology) International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650835 Wed, 25 Jan 2012 18:07:46 +0100 5650835 http://www.medworm.com/index.php?rid=5639751&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F3w604616w2342334%2F Abstract  To assess the relationships between visual acuity (VA), fluorescein angiographic parameters and optical coherence tomography (OCT) patterns in exudative age-related macular degeneration (AMD). Fifty eyes with confirmed diagnosis of new exudative AMD who underwent fluorescein angiography (FA) and OCT evaluation were reviewed retrospectively. The greatest linear diameter of lesion (GLD) by FA and central foveal thickness (CFT) by OCT were measured. The OCT scans were evaluated for the presence of diffuse retinal thickening (D), cystic spaces (C), subretinal fluid (S) and pigment epithelial detachment (P) and five OCT patterns were detected (D + S; C; C + S; P + C + S; P + D + S). Angiographic classification ... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5639751 Tue, 24 Jan 2012 18:09:18 +0100 5639751 http://www.medworm.com/index.php?rid=5639752&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj7105x7k5257h5lh%2F Content Type Journal ArticleCategory Case ReportPages 1-6DOI 10.1007/s10792-011-9511-3Authors Jeffrey M. Goshe, Devers Eye Institute, 1040 NW 22nd Avenue, Portland, OR 97210, USAJennifer Y. Li, Devers Eye Institute, 1040 NW 22nd Avenue, Portland, OR 97210, USAMark A. Terry, Devers Eye Institute, 1040 NW 22nd Avenue, Portland, OR 97210, USA Journal International OphthalmologyOnline ISSN 1573-2630Print ISSN 0165-5701 (Source: International Ophthalmology) International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5639752 Tue, 24 Jan 2012 18:09:17 +0100 5639752 http://www.medworm.com/index.php?rid=5639754&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2629525077003273%2F We report the functional outcome of a patient who had undergone Boston keratoprosthesis type I for extensive ocular surface damage caused by latex of Euphorbia. The milky sap or latex of the Euphorbia plant is highly toxic and an irritant to the skin and eye. Damage to the eye ranges from mild to severe corneal edema, epithelial defects, anterior uveitis, secondary elevated intraocular pressure and, rarely, limbal stem cell deficiency with corneal neovascularization. A restrospective review was conducted of this patient for more than 1 year. During this period he was given subconjunctival bevacizumab injection to regress the corneal vascularization without much benefit, before finally performing Boston keratoprosthesis type I. The patient was evaluated periodically for both anato... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5639754 Tue, 24 Jan 2012 07:33:56 +0100 5639754 http://www.medworm.com/index.php?rid=5639753&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fjr3080538333r055%2F Abstract  To evaluate the outcomes of repeat corneal transplantation, either penetrating keratoplasty (PKP) or Descemet’s stripping automated endothelial keratoplasty (DSAEK), for penetrating keratoplasty grafts which failed due to corneal edema. The charts of 24 eyes with failed PKP grafts, due to corneal edema, which underwent a repeat corneal transplant (PKP in 17 eyes [Group 1] and DSAEK in seven eyes [Group 2]) between 2003 and 2007 were retrospectively reviewed. There was no statistically significant difference in the median postoperative visual acuity between the two groups at 1, 2, or 3 years. In Group 1, two (18%) eyes had a final visual acuity ≥20/40, in contrast to four (80%) eyes in Group 2, which was statistically significant (P = 0.038). Seve... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5639753 Tue, 24 Jan 2012 07:33:56 +0100 5639753 http://www.medworm.com/index.php?rid=5639756&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F1321x535t863tu25%2F In conclusion, rheumatoid nodules may be seen in the conjunctiva even without prior treatment with methotrexate. These nodules may show the severity of the underlying disease and the need for more aggressive treatment. Content Type Journal ArticleCategory Case ReportPages 1-3DOI 10.1007/s10792-012-9514-8Authors Ahmad Kheirkhah, Farabi Eye Hospital, Eye Research Center, Tehran University of Medical Sciences, Qazvin Square, South Kargar Street, Tehran, IranFahimeh Asadi Amoli, Farabi Eye Hospital, Eye Research Center, Tehran University of Medical Sciences, Qazvin Square, South Kargar Street, Tehran, IranAmir A. Azari, Farabi Eye Hospital, Eye Research Center, Tehran University of Medical Sciences, Qazvin Square, South Kargar Street, Tehran, IranSaber Molaei, Farabi Eye Hospital, Eye... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5639756 Tue, 24 Jan 2012 07:33:55 +0100 5639756 http://www.medworm.com/index.php?rid=5639755&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh864k05w41r74017%2F Abstract  The purpose of this study is to report a case of retinal capillary hemangioma treated with ruthenium-106 brachytherapy combined with intravitreal bevacizumab. A 58-year-old woman presented with blurred vision in her left eye for 15 days. Best-corrected visual acuity (BCVA) was counting fingers at 3 m in her left eye. Examination showed a peripheral endophytic retinal capillary hemangioma, with associated macular edema and diffuse hard exudates in a macular star pattern. B-scan ultrasonography revealed a solid, highly reflective retinal tumor measuring 7.1 × 7.5 mm in basal dimension and 3.5 mm in thickness. The hemangioma and macular edema were treated with ruthenium-106 brachytherapy (500 Gy) followed 1 month later with an ... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5639755 Tue, 24 Jan 2012 07:33:55 +0100 5639755 http://www.medworm.com/index.php?rid=5621524&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl04t532m23229076%2F Abstract  A 30-year-old female patient presented to our clinic because of lacrimation from an orifice close to the left lower eyelid. Ocular examinations and analyses revealed uterus didelphys and unilateral renal agenesis associated with a left lacrimal fistula. The patient underwent fistulectomy and external dacryocystorhinostomy. We decided to report on this patient owing to the unusual concurrent systemic abnormalities. Content Type Journal ArticleCategory Case ReportPages 1-3DOI 10.1007/s10792-011-9510-4Authors Ece Turan-Vural, Ophthalmology Clinic, Haydarpasa Numune Education and Research Hospital, Istanbul, TurkeyFatih Atmaca, Ophthalmology Clinic, Umraniye Education and Research Hospital, Istanbul, TurkeyCihan Unlu, Ophthalmology Clinic, Umraniye Education and R... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5621524 Thu, 19 Jan 2012 07:01:12 +0100 5621524 http://www.medworm.com/index.php?rid=5611745&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk815m515vlx7nj66%2F Abstract  To report the case of a patient initially diagnosed with acute posterior multifocal placoid pigment epitheliopathy (APMPPE), characterized by relentless evolution despite high-dose steroid therapy. An interferon-gamma release assay (IGRA) indicated a diagnosis of suspected tuberculous choriocapillaritis and the disease responded only to massive inflammation suppressive therapy and antibiotic therapy. Case report. Review of clinical features and investigational procedures. Smoldering relentless evolution and subsequent arrest of progression could be precisely monitored by indocyanine green angiography (ICGA). The patient did not recover after standard anti-tubercolosis (TB) therapy combined with corticosteroid. A fourth antibiotic had to be added in order to stop t... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5611745 Tue, 17 Jan 2012 07:12:50 +0100 5611745 http://www.medworm.com/index.php?rid=5599782&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F7133333705371232%2F Abstract  To compare the efficacy of 5-fluorouracil (5-FU) with mitomycin C (MMC) in preventing pterygium recurrence when used as an adjuvant following pterygium excision with conjunctival autograft. Low-dose MMC combined with conjunctival autograft is an effective treatment for preventing recurrence following pterygium excision, but safety, cost, and availability limit its use in developing countries. There is a paucity of data on the efficacy of 5-FU when used in Africa as an adjuvant to conjunctival autograft following pterygium excision. This is a randomized controlled prospective trial using either 50 mg/ml 5-FU or 0.01% MMC. Eighty eyes of 80 subjects were studied. Forty-six subjects with a mean age 49.8 ± 13.8 years were treated with 5-FU (USD 13... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5599782 Sat, 14 Jan 2012 16:41:27 +0100 5599782 http://www.medworm.com/index.php?rid=5599783&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fur077276637u2v81%2F Abstract  To report a case of corneal rupture due to blunt trauma occurring 20 years after radial keratotomy (RK) and transverse keratotomy. A 57-year-old woman sustained direct blunt trauma to her right eye. Ocular examination revealed a ruptured globe involving two of the eight RK incisions connected together across the visual axis with iris incarceration in the wound. The transverse keratotomy scars remained intact. The patient underwent primary corneal wound repair and iris repositioning. The postoperative period was uneventful. The patient had a visual acuity of counting fingers at 1 m and is awaiting penetrating keratoplasty. Traumatic rupture of RK incisions can still occur after 20 years. Patients having undergone RK many years before should be warned... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5599783 Sat, 14 Jan 2012 06:55:27 +0100 5599783 http://www.medworm.com/index.php?rid=5599784&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F767315wg514k1787%2F Abstract  The purpose of this study was to determine and compare the prevalence of glaucoma therapy escalation (GTE) after penetrating keratoplasty (PKP) and Descemet’s stripping automated endothelial keratoplasty (DSAEK) in eyes with a surgical indication of pseudophakic corneal edema. A retrospective review was conducted of the medical records of all patients who underwent PKP or DSAEK to treat pseudophakic corneal edema at a tertiary eye care center from January 1 2003 to December 31, 2006. Eyes that were treated with PKP from January 1, 2003 to December 31, 2004 and with DSAEK from January 1, 2005 to December 31, 2006 were included in the statistical analysis. Inclusion criteria included satisfactory preoperative control of intraocular pressure (IOP) and follow-up of ... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5599784 Fri, 13 Jan 2012 16:56:59 +0100 5599784 http://www.medworm.com/index.php?rid=5585362&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F245176010n020843%2F Abstract  Our purpose was to examine toxoplasmic serology in relation to episodes of suspected acute toxoplasmic retinochoroiditis and evaluate its use in the appraisal of patients. The mean values of enzymatic immunoassay (EIA) titers for toxoplasmic antibodies were retrospectively compared in patients with active and inactive toxoplasmosis and in a third group of uveitis cases not caused by toxoplasmosis. The proportion of cases under and above a predefined serology value above cut-off was compared in all groups. Between 1995 and 2010, 97 out of 1,276 new uveitis cases seen at the Centre for Ophthalmic Specialized Care (COS), Lausanne, Switzerland were diagnosed as toxoplasmic retinochoroiditis, of which 51 had documented serology available. The mean EIA values for immuno... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5585362 Tue, 10 Jan 2012 17:00:42 +0100 5585362 http://www.medworm.com/index.php?rid=5585363&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fxx62200wx8502140%2F Abstract  The purpose of this study was to evaluate if administration of artificial tears of high or low-viscosity improve cataract patients’ satisfaction and postoperative pain after cataract surgery. Thirty consecutive patients undergoing bilateral cataract surgery under topical anesthesia were enrolled prospectively. Administration of the following postoperative therapies was randomized: for all participants, one eye was treated with “instant vision” (IV) therapy alone (IV-alone), i.e., this eye remained uncovered. In group 1 (n = 11), the second eye received IV therapy with Hylo-Comod® (HC) eye drops; in group 2 (n = 9), IV with Vidisic® (VS) eye drops; in group 3 (n = 10), an ointment bandage (OB). Postoperative satisfaction, pain sc... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5585363 Mon, 09 Jan 2012 19:36:56 +0100 5585363 http://www.medworm.com/index.php?rid=5573315&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fdh372j6763212v73%2F Abstract  To report on the diagnostic challenge of an adenoid cystic carcinoma arising from the eyelid. A 77-year-old male was referred to our center with a clinical diagnosis of upper eyelid chalazion for a lesion that had appeared 2 years before. A loss of cilia was observed over the cutaneous area of induration, but there was no reddening or ulceration. Incisional biopsy was performed and the specimen was submitted in formalin for histopathological examination. On light microscopy, the lesion was composed of basaloid epithelial and myoepithelial cells that were arranged in strands or nests and associated with cystic spaces that contained a deeply eosinophilic secretory substance and an Alcian blue-positive material, characteristic of adenoid cystic carcinoma. After histo... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5573315 Fri, 06 Jan 2012 16:47:28 +0100 5573315 http://www.medworm.com/index.php?rid=5573317&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv04p7pw73511807w%2F Abstract  To report an unusual case of endogenous fungal endophthalmitis due to Candida dubliniensis. Interventional case report of a 27-year-old immunocompetent male with loss of vision, dense vitritis, and chorioretinal infiltrates, who underwent a diagnostic pars plana vitrectomy. Microbiology cultures obtained by a diagnostic vitrectomy were positive for the growth of C. dubliniensis. This infectious process was then appropriately treated with intravitreal amphotericin B and systemic fluconazole with resolution of the endophthalmitis. Endogenous fungal endophthalmitis is a condition that can masquerade other more common causes of endophthalmitis. Atypical cases of endophthalmitis may benefit from diagnostic pars plana vitrectomy for prompt diagnosis and treatment. Co... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5573317 Thu, 05 Jan 2012 17:05:47 +0100 5573317 http://www.medworm.com/index.php?rid=5573316&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F53767j5127uu7j69%2F This article describes a case of chronic panuveitis as a result of ocular penetration by tarantula setae, and its challenging management that ultimately required pars plana vitrectomy. Interventional case report: A 29-year-old male presented with chronic panuveitis secondary to tarantula-hair penetration. Initial management with mechanical removal of hairs from the cornea and intensive topical steroid therapy for 18 months did not adequately control his symptoms. Pars plana vitrectomy was carried out and at 6-month follow-up the patient was symptom-free without any pharmacological therapy. We propose early pars plana vitrectomy as a management option for treatment-resistant panuveitis in cases of ophthalmia nodosa secondary to setae-related injury. Content Type Journal Arti... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5573316 Thu, 05 Jan 2012 17:05:47 +0100 5573316 http://www.medworm.com/index.php?rid=5573318&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fcm73524588532082%2F Abstract  To report the long-term follow-up and visual outcome after excision of a traumatic iris cyst. A 4-year-old female presented with an iris cyst in her left eye 2 years after corneal laceration repair. An 8 × 7 mm cyst was located between 1 and 6 O’clock on the iris, extending into the anterior chamber. The cyst was surgically removed by dissection from the endothelium and angle by viscoelastic and was submitted for histopathological examination. Postoperative outcomes including visual acuity (VA) and complications over 8 years are reported. Histopathological examination demonstrated fragments of iris tissue extensively covered by a layer of epithelial cells which were present on both the anterior and posterior surfaces of portions of the i... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5573318 Thu, 05 Jan 2012 17:05:46 +0100 5573318 http://www.medworm.com/index.php?rid=5573320&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F27q616087g28321h%2F Abstract  Ocular complications of sexually transmitted diseases are frequently encountered by ophthalmologists and sexual health physicians in everyday practice. Ocular findings may be the first sign of many of the known sexually transmitted diseases. Thus, a high index of suspicion for ocular involvement in patients at risk of sexually transmitted diseases should be borne in mind and these patients should be referred to a specialist in a timely manner. This review focuses on the more significant ocular manifestations of the most common sexually transmitted diseases with which both ophthalmologists and sexual health physicians need to be familiar. In addition, it provides the most recent statistics on these conditions. Content Type Journal ArticleCategory ReviewPages 1-... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5573320 Wed, 04 Jan 2012 06:58:37 +0100 5573320 http://www.medworm.com/index.php?rid=5573319&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa27793674q312t31%2F Abstract  To report clinical manifestations of a female patient with bilateral bacterial keratitis following photorefractive keratectomy (PRK). Bilateral PRK was performed for moderate hyperopia. Bandage contact lenses were fitted at the conclusion of the surgery. Bilateral infectious keratitis with hypopion was diagnosed within 4 days after surgery. Smear and culture were obtained and showed the presence of methicillin-resistant Staphylococcus aureus (MRSA). The patient was treated with systemic prednisone and topical antibiotics (vancomycin, tobramycin and netylmicin) and betamethasone. After 1 month corneal leukoma was still present and remained unchanged during the following 7 months. Infectious keratitis is a rare complication of PRK that appears early in... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5573319 Wed, 04 Jan 2012 06:58:37 +0100 5573319 http://www.medworm.com/index.php?rid=5573321&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Flq3138131t51vw46%2F Abstract  Rare congenital tumors can be localized in the peribulbar area. Here we report an unusual case presented in a 3-year-old child with a history of a congenital tumor in the lacrimal caruncle of the right eye, associated with epiphora and constant discomfort. A surgical resection was performed, and the final histopathological diagnosis was lacrimal caruncle complex choristoma. Choristomas are growths of apparently normal tissue in an abnormal location, which can be situated anywhere in the body, including ocular and peribulbar structures. These almost unknown congenital tumors constitute the most common conjunctival tumors in children and can be interpreted clinically as different lesions, which are only differentiated through precise histopathological analysis. ... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5573321 Tue, 03 Jan 2012 06:44:33 +0100 5573321 http://www.medworm.com/index.php?rid=5562541&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F28n3860462074028%2F We report the case of a 63-year-old woman with Takayasu’s arteritis who experienced progressive visual loss in her right eye (RE) over several months. Visual acuity was 0.4 in the RE, which showed marked retinal arteriovenous dilation and highly irregular arteriolar calibre. She had no light perception in the left eye, which showed diffuse atrophy of the retinal pigment epithelium and prepapillary fibrovascular proliferation. Fluorescein angiography revealed delayed and slow retinal and choroidal circulation and areas of peripheral ischemia. A diagnosis of Takayasu’s retinopathy was made and the non-perfused areas were treated with laser photocoagulation. Takayasu’s disease can result in chronic ocular ischemia. Angiographic examination is particularly important in this context... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562541 Sat, 31 Dec 2011 16:49:03 +0100 5562541 http://www.medworm.com/index.php?rid=5562542&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj7404q4013563645%2F This study demonstrated that the IOP-reducing effects of DTFC and BTFC in patients with POAG are similar. The side-effect profile of BTFC is similar to that of DTFC. Lower occurrence of a burning sensation may improve patient compliance in the BTFC group. Content Type Journal ArticleCategory Original PaperPages 1-5DOI 10.1007/s10792-011-9495-zAuthors Gokhan Gulkilik, Sisli Etfal Training and Research Hospital, Istanbul, TurkeyErsin Oba, Sisli Etfal Training and Research Hospital, Istanbul, TurkeyMahmut Odabası, Sisli Etfal Training and Research Hospital, Istanbul, Turkey Journal International OphthalmologyOnline ISSN 1573-2630Print ISSN 0165-5701 (Source: International Ophthalmology) International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562542 Fri, 30 Dec 2011 07:09:19 +0100 5562542 http://www.medworm.com/index.php?rid=5553597&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr632670l35r83750%2F Abstract  To report on a patient who developed a lamellar macular hole 1 month after an intravitreal pegaptanib sodium injection. Interventional case report. A 66 year old patient developed a lamellar macular hole 1 month after an intravitreal pegaptanib sodium injection for diabetic macular edema (DME). The pathogenesis of the lamellar macular hole in our case can be attributed to the intravitreal injection that may have induced vitreous incarceration, causing vitreoretinal traction at the macula and development of a lamellar macular hole. Alternatively or in association, pegaptanib itself may have caused the lamellar macular hole by inducing sudden reduction of the DME and exacerbation of tangential traction of the posterior vitreous on the overlying macular... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5553597 Wed, 28 Dec 2011 06:53:42 +0100 5553597 http://www.medworm.com/index.php?rid=5553598&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F0100h50n0v756743%2F In conclusion, our study of advanced glaucoma patients undergoing trabeculectomy, vision was preserved with no cases of unexplained loss of central vision. IOP was largely controllable, with cataract being the leading factor decreasing VA at late term. Content Type Journal ArticleCategory Original PaperPages 1-8DOI 10.1007/s10792-011-9494-0Authors Esin F. Baser, Department of Ophthalmology, Faculty of Medicine, Celal Bayar University School of Medicine, Manisa, TurkeyGoktug Seymenoglu, Department of Ophthalmology, Faculty of Medicine, Celal Bayar University School of Medicine, Manisa, TurkeyHuseyin Mayali, Hopa State Hospital, Artvin, Turkey Journal International OphthalmologyOnline ISSN 1573-2630Print ISSN 0165-5701 (Source: International Ophthalmology) International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5553598 Mon, 26 Dec 2011 16:44:54 +0100 5553598 http://www.medworm.com/index.php?rid=5553599&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp437371818p25852%2F We report two recent cases of methanol intoxication in French patients living in Bali. These intoxications were secondary to the consumption of adulterated liquor. Both patients presented acute bilateral loss of vision a few days after methanol ingestion with no sign of recovery. The fundus showed bilateral optic atrophy that was well correlated with retinal nerve fibre layer thickness measured with spectral-domain optical coherence tomography and compatible with toxic optic neuropathy. In one of the patients, macular swelling in one eye was observed. Electroretinograms were normal contrasting with abolished visual evoked potentials. Methanol was isolated from a sample of the beverage with gas chromatography. Methanol intoxication may occur in Asia and therefore adequate information ... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5553599 Mon, 26 Dec 2011 16:44:52 +0100 5553599 http://www.medworm.com/index.php?rid=5527545&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw4145627347754x5%2F The objective of the study is to report the first case of isolated trochlear palsy secondary to Lyme neuroborreliosis in an adult. A 22-year-old male presented with history of flu-like illness and headache, accompanied by vertical binocular diplopia, worse on downgaze and better in upgaze and right head tilt. Physical examination revealed trochlear palsy on the left side with a compensatory head tilt to the opposite side. A subsequent workup for trochlear palsy was conducted, including hematological and cerebral spinal fluid serum studies, and magnetic resonance imaging of the brain. Immunoglobulin (Ig)M and IgG antibodies against Borrelia burgdorferi were positive in serum and cerebral spinal fluid (CSF). Symptoms of double vision completely resolved after 3 weeks of antibiotic ... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5527545 Mon, 19 Dec 2011 16:54:34 +0100 5527545 http://www.medworm.com/index.php?rid=5516541&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy620307j547g9211%2F We report a case of dehiscence of the cataract wound and traumatic expulsive iridodialysis that also exhibited vitreous prolapse. Content Type Journal ArticleCategory Photo EssayPages 1-2DOI 10.1007/s10792-011-9491-3Authors Ane Zurutuza, Department of Ophthalmology, Complejo Hospitalario de Navarra, 31008 Pamplona, SpainJose Andonegui, Department of Ophthalmology, Complejo Hospitalario de Navarra, 31008 Pamplona, SpainLara Berástegui, Department of Ophthalmology, Complejo Hospitalario de Navarra, 31008 Pamplona, Spain Journal International OphthalmologyOnline ISSN 1573-2630Print ISSN 0165-5701 (Source: International Ophthalmology) International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5516541 Thu, 15 Dec 2011 16:50:46 +0100 5516541 http://www.medworm.com/index.php?rid=5507129&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd71371346182u5nn%2F Abstract  The aim of this case series was to report and discuss the clinical, fundus autofluorescence (FAF), and optical coherence tomography (OCT) findings of four eyes of three cases with optic disc pit (ODP)-related serous macular detachment. Three cases were referred to the retina department of our hospital for decreased visual acuities in four of their eyes. In addition to ophthalmological examinations, OCT and FAF were also performed. ODP-related serous macular detachment was detected clinically in all the eyes. OCT also showed two typical components named as ‘bilaminar structure’ in all eyes and OCT and FAF photography showed precipitates in the retinal outer layers of the detachment area in three eyes. OCT and autofluorescence photography findings can support cl... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5507129 Mon, 12 Dec 2011 17:12:33 +0100 5507129 http://www.medworm.com/index.php?rid=5496497&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc2515781409m4220%2F Abstract  Cornea plana is a rare disease in which the cornea is flattened with a low refractive power. In addition to these features, hypermetropia, deep central corneal opacities, hazy corneal limbus, peripheral scleralization of the cornea and early arcus senilis can also be seen. Closed-angle glaucoma may occur as a result of shallow anterior chamber and narrow angle; however, open-angle glaucoma has also been reported in these patients. Measuring the real intraocular pressure (IOP) value of such eyes is difficult since tonometers are affected by corneal curvature. Therefore, the diagnosis of glaucoma may be delayed for a long time. In this case report we aimed to present a case of cornea plana with early open-angle glaucoma and to investigate which tonometer was appropr... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5496497 Sat, 10 Dec 2011 16:55:04 +0100 5496497 http://www.medworm.com/index.php?rid=5488872&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd8437k1wl47hxj83%2F We describe the case of a 77-year-old man who received multiple penetrating keratoplasties (PKPs) and subsequent placement of an AlphaCor artificial cornea. Examination showed total corneal infiltration as well as an AlphaCor that was partially dehisced from the host cornea. After explantation, the implant and adjacent host tissue underwent hematoxylin and eosin staining and high-resolution scanning electron microscopy (HR-SEM). Histopathologic analysis of the specimens revealed infiltration of the skirt pores by reactive corneal fibroblasts. Although the AlphaCor implant is an established method of treating multiple failed PKPs, in this case, HR-SEM imaging strongly suggests that the strength of the interface between the implant and corneal tissue is highly dependent on collagen dep... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5488872 Wed, 07 Dec 2011 16:42:51 +0100 5488872 http://www.medworm.com/index.php?rid=5488873&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F526h13589q613v43%2F We present a case of AIDS-related KS of the conjunctiva and also discuss recent literature. Content Type Journal ArticleCategory Photo EssayPages 1-2DOI 10.1007/s10792-011-9483-3Authors Francisco Jover, Infectious Disease Unit, Hospital Universitario de San Juan, Ctra. Valencia s/n, 03550 Alicante, SpainJ. Peris, Infectious Disease Unit, Hospital Universitario de San Juan, Ctra. Valencia s/n, 03550 Alicante, SpainJ. M. Cuadrado, Infectious Disease Unit, Hospital Universitario de San Juan, Ctra. Valencia s/n, 03550 Alicante, Spain Journal International OphthalmologyOnline ISSN 1573-2630Print ISSN 0165-5701 (Source: International Ophthalmology) International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5488873 Wed, 07 Dec 2011 16:42:50 +0100 5488873 http://www.medworm.com/index.php?rid=5488874&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx81546011m7430r3%2F Abstract  To study the efficacy and safety of sutureless amniotic membrane transplantation combined with narrow-strip conjunctival autograft and to investigate the clinical outcomes. Thirty eyes of 30 patients with primary pterygia were treated in this institutional study with excision followed by sutureless amniotic membrane transplantation combined with narrow-strip conjunctival autograft using fibrin glue tissue adhesive. The main outcome measures were the operating time for ocular surface reconstruction, the size of the pterygium and of the conjunctival autograft, postoperative complications, subjective complaints, and recurrences. The mean pterygium size was 3.12 ± 0.92 mm and the mean operating time was 4.58 ± 1.10 min. Twenty-nine patie... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5488874 Tue, 06 Dec 2011 19:09:26 +0100 5488874 http://www.medworm.com/index.php?rid=5488875&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F5312473268203242%2F We report a case of a 37-year-old male with a conjunctival melanocytic nevus presenting in a rare, peripunctal location with preservation of the lacrimal canaliculus and punctum. Content Type Journal ArticleCategory Case ReportPages 1-3DOI 10.1007/s10792-011-9485-1Authors Cindy S. Hwang, Department of Ophthalmology, Baylor College of Medicine, Cullen Eye Institute, 1977 Butler Boulevard, Houston, TX 77030, USASeongmu Lee, Department of Ophthalmology, Baylor College of Medicine, Cullen Eye Institute, 1977 Butler Boulevard, Houston, TX 77030, USAMichael T. Yen, Department of Ophthalmology, Baylor College of Medicine, Cullen Eye Institute, 1977 Butler Boulevard, Houston, TX 77030, USA Journal International OphthalmologyOnline ISSN 1573-2630Print ISSN 0165-5701 (Source: Internat... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5488875 Mon, 05 Dec 2011 17:34:48 +0100 5488875 http://www.medworm.com/index.php?rid=5478514&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F50712r0736m78121%2F We report on a patient who developed corneal haze and permanent ptosis after strabismus surgery. Formaldehyde-disinfected sodium hyaluronate which was used to protect the corneal epithelium during surgery was thought to have induced keratopathy and other findings. To our knowledge, this is the first report of corneal haze formation together with ptosis secondary to formaldehyde toxicity as a complication of strabismus surgery. Content Type Journal ArticleCategory Case ReportPages 1-3DOI 10.1007/s10792-011-9487-zAuthors Berrak Sekeryapan, Ophthalmology Department, Rize University, School of Medicine, Rize, TurkeyAli Kurt, Ophthalmology Department, Rize University, School of Medicine, Rize, TurkeyKemal Turkyilmaz, Ophthalmology Department, Rize University, School of Medicine, Rize,... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5478514 Sat, 03 Dec 2011 16:50:31 +0100 5478514 http://www.medworm.com/index.php?rid=5478515&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg7g0602175326585%2F Abstract  To describe a case of herpetic keratitis after corneal collagen cross-linking (CXL) with riboflavin and ultraviolet-A for progressive keratoconus. A 31-year-old woman with rapidly progressive keratoconus in the left eye was treated with CXL. Four days postoperatively, a dendritic ulcer developed in the treated eye. The diagnosis was confirmed with polymerase chain reaction analysis of the corneal swab for herpes simplex. The patient had no prior history of herpetic eye disease or cold sores. The keratitis resolved in 10 days with treatment. At 1 month, the visual acuity was stable, but a mild superficial opacity was noted. Herpetic keratitis can be induced by CXL even in patients with no history of previous herpetic eye disease. Early diagnosis and prope... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5478515 Fri, 02 Dec 2011 18:10:03 +0100 5478515 http://www.medworm.com/index.php?rid=5478516&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ffx774431vv0gx086%2F We report a case in which clouding and opacification of an IOL occurred intraoperatively within a few seconds of implantation into the capsular bag after routine phacoemulsification. This phenomenon occurred due to the sudden change in temperature of a very cold IOL being implanted into the eye at body temperature. The opaqueness lasted for about 3 h then cleared without any residual or permanent change to the IOL. This case highlights the effect of environmental factors on hydrophillic acrylic IOLs. It is particularly important in cold countries and during the winter months. It also reinforces the practice of storing the IOL at a correct temperature to avoid sudden fluctuations in its surrounding environment. Content Type Journal ArticleCategory Case ReportPages 1-2DOI 10.... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5478516 Fri, 02 Dec 2011 18:10:02 +0100 5478516 http://www.medworm.com/index.php?rid=5460169&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk10810v785p37332%2F We report a case of secondary angle-closure glaucoma due to 360°PS 5 years after a phacovitrectomy for recurrent vitreous haemorrhage secondary to diabetic retinopathy. To our knowledge this is the first such reported case of this potentially sight-threatening complication of phacovitrectomy. We discuss our successful management of our patient, as well as potential risk factors and preventative measures. Content Type Journal ArticleCategory Case ReportPages 1-2DOI 10.1007/s10792-011-9475-3Authors Osama Makhzoum, University Hospitals Coventry and Warwickshire NHS Trust, University Hospital, Clifford Bridge Road, Coventry, CV2 2DX UKNiall James Crosby, University Hospitals Coventry and Warwickshire NHS Trust, University Hospital, Clifford Bridge Road, Coventry, CV2 2DX UKMark... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5460169 Mon, 28 Nov 2011 16:49:58 +0100 5460169 http://www.medworm.com/index.php?rid=5450703&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv8378371t3127125%2F We present a case of reversible CDDP-associated branch retinal artery occlusion. Content Type Journal ArticleCategory Case ReportPages 1-4DOI 10.1007/s10792-011-9476-2Authors Arijit Mitra, Birmingham and Midland Eye Centre, City Hospital, Dudley Road, Birmingham, West Midlands B18 7QH, UKMatthew R. Edmunds, Birmingham and Midland Eye Centre, City Hospital, Dudley Road, Birmingham, West Midlands B18 7QH, UKNawaz Walji, Queen Elizabeth Hospital, Edgbaston, Birmingham, West Midlands, UKIndrajit N. Fernando, Queen Elizabeth Hospital, Edgbaston, Birmingham, West Midlands, UKRobert A. H. Scott, Birmingham and Midland Eye Centre, City Hospital, Dudley Road, Birmingham, West Midlands B18 7QH, UKPeter Good, Birmingham and Midland Eye Centre, City Hospital, Dudley Road, Birmingham, West Midl... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5450703 Wed, 23 Nov 2011 16:40:24 +0100 5450703 http://www.medworm.com/index.php?rid=5443510&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp278628p02861332%2F Abstract  To investigate whether vitreous fluid levels of vascular endothelial growth factor (VEGF), pigment epithelium-derived factor (PEDF), and soluble intercellular adhesion molecule 1 (sICAM-1) influence visual prognosis and macular edema in patients with central retinal vein occlusion (CRVO). A prospective observational study was performed in 31 consecutive CRVO patients (31 eyes) with macular edema who underwent vitrectomy. Best-corrected visual acuity (BCVA), retinal thickness (examined by OCT), and vitreous fluid levels of VEGF, PEDF, and sICAM-1 were determined. Patients were followed for at least 6 months after surgery. Both visual acuity and retinal thickness showed significant improvement at 6 months postoperatively (P = 0.012 and P <... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5443510 Mon, 21 Nov 2011 18:08:49 +0100 5443510 http://www.medworm.com/index.php?rid=5443511&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx3212v7337492q53%2F In this study, we investigated the visual performance of two aspherical intraocular lenses (IOLs), Tecnis ZCB00 and Acrysof SN60WF, by measuring high-order aberration, visual evoked potentials (VEP), retinal sensitivity, and fixation stability by MP-1 microperimetry and contrast sensitivity values. Twenty-two patients with age-related cataract were randomly allocated to either the Tecnis or the Acrysof group. All measurements were taken from patients of both groups 2 months postoperatively. Statistical analysis was performed with Student’s t test, where P-values < 0.05 were considered significant. Results were not statistically significant with regard to high-order aberration, VEP, retinal sensitivity, and fixation stability. However, the contrast sensitivity value... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5443511 Sat, 19 Nov 2011 16:54:40 +0100 5443511 http://www.medworm.com/index.php?rid=5411284&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fbn77n282633871j1%2F Content Type Journal ArticleCategory Letter to the EditorPages 1-2DOI 10.1007/s10792-011-9478-0Authors Nimish Shah, Department of Gloucestershire Eye, Cheltenham General Hospital, Gloucestershire Hospitals NHS Foundation Trust, Sandford Road, Cheltenham, GL53 7AN, UKSuzanne Turner, Department of Gloucestershire Eye, Cheltenham General Hospital, Gloucestershire Hospitals NHS Foundation Trust, Sandford Road, Cheltenham, GL53 7AN, UKRobert L. Johnston, Department of Gloucestershire Eye, Cheltenham General Hospital, Gloucestershire Hospitals NHS Foundation Trust, Sandford Road, Cheltenham, GL53 7AN, UK Journal International OphthalmologyOnline ISSN 1573-2630Print ISSN 0165-5701 (Source: International Ophthalmology) International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5411284 Fri, 11 Nov 2011 16:45:17 +0100 5411284 http://www.medworm.com/index.php?rid=5411285&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj056j847x68622p7%2F Abstract  We investigated differences in color discrimination between the fellow eye and the affected eye successfully treated for unilateral age-related macular degeneration (AMD) in a 69-year-old male patient with protanopia. His best-corrected visual acuity (BCVA) was 1.2 in the right eye (RE) and 0.2 in the left eye (LE). Fundus and angiographic findings showed classic choroidal neovascularization (CNV) secondary to AMD in the LE. BCVA of the LE improved to 0.4, and CNV resolved by 15 months after initiating combined anti-vascular endothelial growth factor and photodynamic therapies. After CNV closure, the Farnsworth dichotomous was performed, showing confusion patterns of the protan axis in either eye. The Farnsworth-Munsell 100-hue test showed a total error score ... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5411285 Thu, 10 Nov 2011 16:55:01 +0100 5411285 http://www.medworm.com/index.php?rid=5411286&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F25310r02v1k02046%2F We report the case of a 76-year-old woman with scrolled Descemet’s membrane detachment (DMD) that was successfully treated by an intracameral injection of 1.8% sodium hyaluronate. During phacoemulsification cataract surgery, an undulating DMD involving the central cornea was observed and air tamponade into the anterior chamber was performed. The patient underwent surgical repair 2 weeks after the unsuccessful intracameral air injection. To increase the tamponade pressure and surface tension on the scrolled flap, viscoelastic material was injected into the air-filled anterior chamber. Corneal edema started subsiding clinically after the injection of sodium hyaluronate. Descemetopexy with sodium hyaluronate can successfully repair scrolled DMD and injection of viscoelastic mater... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5411286 Wed, 09 Nov 2011 17:58:35 +0100 5411286 http://www.medworm.com/index.php?rid=5390677&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa120g50003317770%2F Abstract  To investigate whether retinal surface imaging by Cirrus high-definition optical coherence tomography (HD-OCT) clearly depicts the development process of a dissociated optic nerve fiber layer (DONFL) appearance after macular hole (MH) surgery. We reviewed the medical records of the patients who underwent MH surgery with internal limiting membrane peeling. The cases were then selected using three principal criteria: (1) surgeries performed by the same surgeon (S. K.), (2) pre- and postoperative Cirrus HD-OCT imaging, and (3) minimal follow-up of 3 months. All cases received a complete ophthalmologic examination. The presence/absence of a DONFL appearance was determined using a retinal surface image provided by Cirrus HD-OCT. Color fundus photographs were also ... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5390677 Sat, 05 Nov 2011 17:10:43 +0100 5390677 http://www.medworm.com/index.php?rid=5390678&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj0752m4w08204770%2F We report on a patient with an overhanging bleb several years following trabeculectomy surgery with mitomycin C. Content Type Journal ArticleCategory Photo EssayPages 1-2DOI 10.1007/s10792-011-9477-1Authors Kapil G. Kapoor, Department of Ophthalmology, The University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555, USAMisha F. Syed, Department of Ophthalmology, The University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555, USA Journal International OphthalmologyOnline ISSN 1573-2630Print ISSN 0165-5701 (Source: International Ophthalmology) International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5390678 Sat, 05 Nov 2011 15:44:40 +0100 5390678 http://www.medworm.com/index.php?rid=5390679&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr2h11117x25v5473%2F Abstract  Ocular decompression retinopathy (ODR) is a rare complication of sudden lowering of intraocular pressure (IOP) in glaucoma and ocular hypertension. An 80-year-male, a known case of chronic open-angle glaucoma for 13 years, had his IOP controlled by multiple topical antiglaucoma medications. There was an increase in IOP, progression of optic disc cupping and visual field loss along with cataract over the past 6 months. The patient underwent uneventful phacoemulsification with posterior chamber intraocular lens (PCIOL) and penetrating trabeculectomy. Postoperatively, the trabeculectomy bleb was flat and IOP was 44 mmHg and was not controlled by bleb massage. Bleb needling and suture lysis were performed after 2 weeks. The IOP dropped from 44 to 6... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5390679 Fri, 04 Nov 2011 16:56:32 +0100 5390679 http://www.medworm.com/index.php?rid=5325797&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm81412868jk772u0%2F We report the clinical history of a child affected by Crohn’s disease in which uveitis precedes intestinal involvement by years and occurs with the atypical features of anterior chronic inflammation complicated by unilateral optic disc edema, rather than recurrent anterior uveitis with sudden onset which has been more widely reported in inflammatory bowel diseases. The uveitis onset occurred 8 years before symptoms of the primary intestinal disease, while in inflammatory bowel diseases the intestinal inflammation typically precedes ocular symptoms, and ocular inflammation only occasionally precedes inflammatory involvement of the bowel. Content Type Journal ArticleCategory Case ReportPages 1-3DOI 10.1007/s10792-011-9470-8Authors Maria Pia Paroli, Ocular Immunovirology Se... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5325797 Sat, 15 Oct 2011 05:49:33 +0100 5325797 http://www.medworm.com/index.php?rid=5325798&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F4070222k36w7pj0g%2F Abstract  Retinal injuries caused by accidental laser exposure include retinal or vitreous hemorrhages, macular holes and edema. We describe the imaging of a bilateral macular lesion secondary to accidental Nd:YAG laser exposure. Observational case report. We performed color photography, fluorescein angiography and autofluorescence (AF) with a scanning laser ophthalmoscope, as well as time-domain and spectral-domain optical coherence tomography (OCT). After accidental exposure to a 1064 nm Nd:YAG laser, a patient experienced blurred vision in the left eye (LE) with visual acuity of 20/60. Color, fluorescein angiography and OCT imaging showed a retinal hemorrhage in the foveal area of the left eye and in the inferomacular region of the asymptomatic right eye. Steroid th... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5325798 Fri, 14 Oct 2011 15:43:49 +0100 5325798 http://www.medworm.com/index.php?rid=5325799&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu72775r676135n52%2F Abstract  To evaluate the corneal findings in hydrogel contact lens wearers by in vivo confocal scanning microscopy. One hundred and forty-two eyes of 71 myopic contact lens wearers (group 1) and 142 eyes of 71 non-contact lens wearers (group 2), whose age, gender and refractive error matched, were enrolled in order to detect the corneal changes by in vivo confocal microscopy through the central cornea. The average age was 25.5 ± 5.7 (16–52) and 25.6 ± 5.6 (17–49) in groups 1 and 2, respectively. The mean duration of contact lens wear was 43.9 ± 15.3 (6–240) months. Anterior keratocyte density was 667.5 ± 128.3 cells/mm2 in group 1 and 821.4 ± 136.7 cells/mm2 in group 2 (P = 0.001). Posterior keratocyte de... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5325799 Fri, 14 Oct 2011 15:43:48 +0100 5325799 http://www.medworm.com/index.php?rid=5317256&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd53673x74h647675%2F Intravitreal haemoglobin spherulosis: an unusual sequela of intraocular haemorrhage Content Type Journal ArticleCategory Case ReportPages 1-3DOI 10.1007/s10792-011-9465-5Authors Elizabeth Insull, Ophthalmology Department, Waikato Hospital, Hamilton, New ZealandStephen Guest, Ophthalmology Department, Waikato Hospital, Hamilton, New ZealandDushyanti Samarasinghe, Ophthalmology Department, Waikato Hospital, Hamilton, New Zealand Journal International OphthalmologyOnline ISSN 1573-2630Print ISSN 0165-5701 (Source: International Ophthalmology) International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5317256 Wed, 12 Oct 2011 16:06:50 +0100 5317256 http://www.medworm.com/index.php?rid=5317258&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fbn3821u9377574m8%2F Content Type Journal ArticleCategory Case ReportPages 1-3DOI 10.1007/s10792-011-9467-3Authors Jain Ashish, Aravind Eye Hospital, Madurai, IndiaR. Muralidhar, Aravind Eye Hospital, Madurai, IndiaP. Vijayalakshmi, Aravind Eye Hospital, Madurai, IndiaSundaram Meenakshi, Aravind Eye Hospital, Madurai, India Journal International OphthalmologyOnline ISSN 1573-2630Print ISSN 0165-5701 (Source: International Ophthalmology) International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5317258 Mon, 10 Oct 2011 15:04:47 +0100 5317258 http://www.medworm.com/index.php?rid=5317257&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu9x6l02862646736%2F Abstract  To document the rate of self-reported compliance and glaucoma-related knowledge in Swiss patients and to identify risk factors for their poor compliance. This was an observational study, including a total of 200 consecutive patients already under glaucoma medication in two Swiss tertiary glaucoma clinics (Geneva and Bern). Personal characteristics, presence of systemic disease, compliance with glaucoma medication, attitude to the ophthalmologist, and glaucoma-related attitudes were ascertained by means of a predetermined questionnaire with 40 questions. Patients were subsequently assessed for the ability to correctly instil placebo eye drops. Non-compliance with glaucoma medication was defined as omitting more than two doses a week as reported by the patient. Logi... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5317257 Mon, 10 Oct 2011 15:04:47 +0100 5317257 http://www.medworm.com/index.php?rid=5306481&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe6l6677084450133%2F Abstract  To compare changes in posterior vitreous detachment (PVD) following intravitreal injection of bevacizumab and triamcinolone in diffuse diabetic macular edema in middle-aged type 2 diabetes patients and to correlate this change with change in central macular thickness (CMT). Design: cross sectional study. Fifteen consecutive patients treated by intravitreal bevacizumab (group A) and ten patients treated by intravitreal triamcinolone (group B). Institutional study carried out by retrospective analysis of patient registers including serial optical coherence tomography (OCT) images at baseline, and after 1 and 4 months. A central macular thickness (CMT) and vitreomacular relationship was noted on OCT. PVD was graded on a linear scale (0–4). Change in grade of P... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5306481 Fri, 07 Oct 2011 05:46:42 +0100 5306481 http://www.medworm.com/index.php?rid=5212332&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F5346twmq33m757ur%2F This study suggests that in Korean NTG patients, despite relatively similar IOPs between progressed and stable patients, and based on multivariate regression analysis, IOP may be a risk factor for glaucomatous progression. Content Type Journal ArticleCategory Original PaperPages 1-7DOI 10.1007/s10792-011-9463-7Authors Kyoung Tak Ma, Siloam Eye Hospital, Gangseo-gu, Seoul, South KoreaChan Yun Kim, Shinchon Severance Hospital, Yonsei University, Seodaemun-gu, Seoul, South KoreaGong Je Seong, Gangnam Severance Hospital, Yonsei University, Gangnam-gu, Seoul, South KoreaSeung Hyuck Lee, Yonsei Plus Eye Center, Sungnam-si, Kyunggi-do, South KoreaJong Woon Park, NHIC Ilsan Hospital, Goyang-si, Kyounggi-do, South KoreaSeung Joo Ha, Soon Chun Hyang University Hospital, Yongsan-gu, Seoul, So... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5212332 Thu, 08 Sep 2011 06:01:22 +0100 5212332 http://www.medworm.com/index.php?rid=5148589&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk69272x8uku28rg1%2F Abstract  The purpose of this study is to report the importance of ultrasound biomicroscopy (UBM) in the diagnosis of Descemet’s membrane detachment (DMD) and the efficacy of sulfur hexafluoride (SF6) gas in its management. DMD was identified by UBM in a 22-year-old woman with juvenile glaucoma who underwent deep sclerectomy surgery and developed severe corneal oedema postoperatively. SF6 gas 15% was injected into the anterior chamber. The procedure resulted in reattachment of Descemet’s membrane and a completely clear cornea. DMD can be easily overlooked or misdiagnosed after non-penetrating glaucoma surgery. UBM is helpful in diagnosis and management of DMD and descemetopexy with SF6 gas can give good results. Content Type Journal ArticleCategory Case ReportPages 1... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5148589 Fri, 19 Aug 2011 15:58:55 +0100 5148589 http://www.medworm.com/index.php?rid=5148590&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp5228811230gq161%2F Content Type Journal ArticleCategory Photo EssayPages 1-3DOI 10.1007/s10792-011-9446-8Authors Eleni Loukianou, Moorfields Eye Hospital, 25A Bavaria Road, London, N19 4EU UK Journal International OphthalmologyOnline ISSN 1573-2630Print ISSN 0165-5701 (Source: International Ophthalmology) International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5148590 Fri, 19 Aug 2011 06:39:20 +0100 5148590 http://www.medworm.com/index.php?rid=5148591&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb2x50p3k21125186%2F Abstract  Corneal collagen cross-linking (CXL) using riboflavin and ultraviolet-A irradiation is a common method of tissue stabilization and has been developed primarily to address the need of treating keratoconus. CXL’s promising results on keratoconus indicated that it might be effective in other corneal diseases as well. This new treatment promises a slowing effect on the progression of these diseases and its initial results show that it is safe and reasonably curative. The purpose of this review is to critically evaluate this treatment, to explore its benefits, to highlight its limitations in terms of efficacy and long-term safety and finally to identify areas for future research in this topic with a significant potential to change the way we treat our patients. In ad... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5148591 Wed, 17 Aug 2011 05:57:48 +0100 5148591 http://www.medworm.com/index.php?rid=5148592&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ftj45365753504158%2F Abstract  To compare the effect of Nd:YAG laser capsulotomy and primary posterior continuous capsulorhexis (PPCC) combined with phacoemulsification on macular thickness using optical coherence tomography (OCT) in adults. This prospective comparative interventional study included 32 eyes of 30 patients who underwent Nd:YAG laser capsulotomy and 33 eyes of 33 patients who underwent cataract surgery with PPCC. Detailed ocular examinations, including macular thickness measurements by OCT, were performed in all patients preoperatively and postoperatively on the 1st day, 1st week, and 1st, 3rd and 6th months. No significant differences were found in macular thickness between the two groups in preoperative and postoperative follow-up. No cystoid changes were observed in OCT during ... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5148592 Sun, 14 Aug 2011 05:44:49 +0100 5148592 http://www.medworm.com/index.php?rid=5148593&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F161w763312066662%2F Abstract  The purpose of this study is to report a case of disseminated histoplasmosis in a patient with uveitis, after treatment with infliximab. The method employed in this study is single case report. Infliximab can be useful in controlling idiopathic uveitis, but can give rise to disseminated histoplamosis, especially in patients living in geographic areas where histoplasmosis is endemic. Clinicians should be aware of the possibility of rapid onset histoplasmosis in patients receiving anti-tumor necrosis factor agents. In such cases, these agents should be immediately stopped, investigations performed, and appropriate treatment started. Content Type Journal ArticleCategory Case ReportPages 1-3DOI 10.1007/s10792-011-9459-3Authors Lik Thai Lim, Ophthalmology Registr... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5148593 Sun, 14 Aug 2011 05:44:47 +0100 5148593 http://www.medworm.com/index.php?rid=5081834&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F7kw1005170417361%2F We describe the surgical technique of DALK called ‘Double Bubble’ technique that allows the surgeon to definitely and immediately identify the formation of an adequate big bubble. DALK was performed using the ‘Double Bubble’ technique in twelve eyes of twelve patients with corneal stromal pathologies (keratoconus, 9 eyes; macular corneal dystrophy, 2 eyes; postinfectious keratitis corneal stromal scar, 1 eye) at the Royal Victorian Eye and Ear Hospital, Melbourne. Big bubble was successfully formed in 10 eyes. Maximum-depth deep lamellar keratoplasty was performed in two eyes. There were no instances of intraoperative perforation of the DM. All grafts were clear at last follow-up. Best-corrected visual acuity of ≥20/40 was achieved in all the cases at last follow-up (... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5081834 Fri, 29 Jul 2011 16:05:54 +0100 5081834 http://www.medworm.com/index.php?rid=5058570&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd17136l786072125%2F We report a case of focal subretinal abscess in a 27-year-old diabetic man presenting with Staphylococcus sepsis. The follow-up study was based on visual acuity (VA), fundus photography, fluorescein angiography, ultrasound and optical coherence tomography, and an intravenous specific antibiotic was administered with an unusual good outcome. Content Type Journal ArticlePages 1-5DOI 10.1007/s10792-011-9454-8Authors A. Trigui, Department of Ophthalmology, Habib Bourguiba University Hospital, Sfax, TunisiaH. Laabidi, Department of Ophthalmology, Habib Bourguiba University Hospital, Sfax, TunisiaM. Khairallah, Department of Ophthalmology, Fattouma Bourguiba University Hospital, Monastir, TunisiaJ. Féki, Department of Ophthalmology, Habib Bourguiba University Hospital, Sfax, Tunisia ... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5058570 Tue, 19 Jul 2011 06:07:10 +0100 5058570 http://www.medworm.com/index.php?rid=5058571&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl84711384133746p%2F Abstract  The aim of this article is to report a case of Aspergillus chorioretinitis successfully treated with intravitreal voriconazole based on an interventional case report. An immunodeficient patient, 34 years old, receiving systemic antifungal treatment for 1 month for invasive aspergillosis with necrotizing pneumonia and brain metastasis, who presented with blurred vision in his left eye. Visual acuity (VA) was 20/20 in his right eye, and 8/20 in his left eye. Ophthalmological examination showed a paramacular nodular yellowish chorioretinal lesion with intraretinal hemorrhages, in the absence of vitritis or anterior uveitis. The patient was treated with one dose of intravitreal voriconazole (100 μg/0.1 ml). One week after the intravitreal injection, the... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5058571 Tue, 19 Jul 2011 06:07:09 +0100 5058571 http://www.medworm.com/index.php?rid=5042874&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy6719ul480k5678x%2F Abstract  To compare the tonometric recordings of the Tono-Pen AVIA (TPA) with intraocular pressure (IOP) recordings made with Goldmann applanation tonometry (GAT) and non-contact tonometry (NCT). This prospective, observational, comparative case series consisted of 180 eyes of 180 subjects (50 patients with glaucoma and 130 healthy controls). NCT was performed first, followed by GAT and TPA measurement after a 5-min break. The mean age of the patients enrolled in the study was 43.99 ± 16.67 years. The limits of agreement (confidence interval 95%) as calculated from the Bland–Altman plots for TPA–GAT and TPA–NCT were +8.7 to −7.7 and +8.6 to −9.6 mmHg in glaucoma patients. In healthy subjects these values were +4.8 to −5.1 and +6.2 to −5.2&... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5042874 Fri, 15 Jul 2011 05:55:29 +0100 5042874 http://www.medworm.com/index.php?rid=5032179&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F7665n6023qq18ul2%2F Abstract  To evaluate the topographic changes of cornea after pars plana vitrectomy (PPV) with the 23-gauge- (23-G) transconjunctival sutureless vitrectomy (TSV) system within the first postoperative month. In this prospective study, corneal topographic changes were evaluated in 24 eyes of 24 patients who underwent PPV with the 23-G TSV system. All eyes underwent computer-assisted videokeratography using NAVIS (Nidek Advanced Vision Information System) software preoperatively and at the first day, first week, and first month postoperatively. The topographic parameters that were analyzed statistically were the average corneal power (ACP), corneal surface cylinder (CSC), surface asymmetry index (SAI), and surface regularity index (SRI). Mean induced astigmatism was estimated ... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5032179 Wed, 13 Jul 2011 06:18:05 +0100 5032179 http://www.medworm.com/index.php?rid=5032180&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn5668511p3364131%2F Abstract  The incidence of fungal keratitis has increased in recent years. Since accurate and rapid diagnosis is important for the proper management of this infection, we evaluated the use of nested PCR to detect Aspergillus-specific DNA in corneal scrapings for the diagnosis of Aspergillus keratitis. From April 2005 to September 2008, patients with eye findings suspicious for fungal keratitis were enrolled for corneal sampling. After ocular examination, we carried out laboratory testing including direct microscopy and culture examination of corneal scrapings, nested PCR and histopathological examination of the corneal tissues obtained at surgery. Of the 57 infected eyes suspicious for fungal keratitis, 32 (56.14%) were reported as Aspergillus keratitis by PCR assay, from whi... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5032180 Wed, 13 Jul 2011 06:18:04 +0100 5032180 http://www.medworm.com/index.php?rid=5032181&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff6003u6q15606132%2F This study was performed to assess the usefulness of color vision, photo stress recovery time (PSRT), and visual evoked potentials (VEP) in early detection of ocular toxicity of HCQ, in patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). 86 patients were included in the study and divided into three groups: (1) with history of HCQ use: interventional 1 (Int.1) without fundoscopic changes and Int.2 with fundoscopic changes; and (2) without history of HCQ use, as control. Visual field, color vision, PSRT and VEP results were recorded for all patients and the effect of age, disease duration, treatment duration and cumulative dose of HCQ on each test was assessed in each group. There was a significant relationship among PSRT and age, treatment duration, cumulat... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5032181 Tue, 12 Jul 2011 05:58:20 +0100 5032181 http://www.medworm.com/index.php?rid=4915941&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F1814224212745157%2F This study tests the hypothesis that subjects with proliferative diabetic retinopathy (PDR) have a detectable rise in levels of serum vascular endothelial growth factor (VEGF), which is an important regulator of angiogenesis. Our investigation aims to evaluate plasma VEGF changes after pan-retinal photocoagulation (PRP) in diabetic patients. Twenty-nine type two diabetic patients (17 male, 12 female: mean age 53.13 ± 12.22 years) with PDR secondary to diabetes were studied. Blood samples were obtained before and at 2 months after the last PRP session. Serum VEGF levels were measured by ELISA. After PRP, the mean serum VEGF decreased, but this reduction was not remarkable (88.68 ± 71.09 vs. 77.01 ± 60.33 ng/ml) (P = 0.18). There... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4915941 Tue, 07 Jun 2011 05:46:24 +0100 4915941 http://www.medworm.com/index.php?rid=4897291&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fjm2g8844191w6v78%2F Abstract  A 10-year-old girl presented with visual loss in her right eye. Best-corrected visual acuity was 20/50 in the right eye and 20/20 in the left eye. Dilated funduscopic examination revealed a yellowish elevated lesion near the optic disc with macular edema and hemorrhage on the inferotemporal vascular arcade in the right eye. Fluorescein angiography showed a hyperfluorescent lesion consistent with choroidal neovascularization (CNV) and optical coherence tomography (OCT) showed a peripapillary lesion with subretinal fluid elevating the neurosensory retina in the macular area. With a diagnosis of unilateral idiopathic peripapillary CNV, the patient underwent photodynamic therapy (PDT) with verteporfin. At the four month follow-up, visual acuity increased to 20/25 and ... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4897291 Fri, 03 Jun 2011 05:57:38 +0100 4897291 http://www.medworm.com/index.php?rid=4897290&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft370mp1867460083%2F Abstract  To study the correlation between the results of frequency-doubling technology perimetry (FDTP), visual function (visual acuity, contrast vision, standard automated perimetry (SAP)) and the thickness of the retinal nerve fiber layer (RNFL) throughout the course of multiple sclerosis (MS). Sixty-six eyes of thirty-three patients suffering from MS were chosen. Thirty-five eyes had a previous history of optic neuritis (ON group) and thirty-one eyes had no previous history of optic neuritis (non-ON group). The FDTP was performed with the N-30 screening program. Visual acuity was determined with the Snellen scale and the ETDRS (Early Treatment Diabetic Retinopathy Study) scale, the contrast vision with the Pelli-Robson and Sloan tests and the SAP with the Humphrey 750 p... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4897290 Fri, 03 Jun 2011 05:57:38 +0100 4897290 http://www.medworm.com/index.php?rid=4897292&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb61n13h325121120%2F Abstract  Acute depigmentation of the iris is a new condition characterized by pigment dispersion in the anterior chamber, depigmentation of the iris stroma, and pigment deposition in the anterior chamber angle. A 33-year-old woman using a topical corticosteroid every 2 h for the treatment of acute iridocyclitis was referred to our clinic to seek another opinion because her symptoms had not improved. An ocular evaluation of the patient revealed pigment precipitates on the corneal endothelium, pigment dispersion in the anterior chamber, symmetrical diffuse depigmentation, granularity of the iris stroma, and pigment deposition in the trabecular meshwork. These findings suggested a diagnosis of bilateral acute depigmentation of the iris (BADI) instead of iridocyclitis. Clinici... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4897292 Thu, 02 Jun 2011 06:04:23 +0100 4897292 http://www.medworm.com/index.php?rid=4897293&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft30g50244514278p%2F We report an unusual case of asymptomatic subconjunctival entrapment of a cilium. A 64-year-old man presented with a 3 month history of a painless black line in the conjunctiva of the left eye, and slit-lamp examination revealed a cilium under the conjunctiva. The patient remained asymptomatic without conjunctival edema or hyperemia during a 2 week follow-up. To the best of our knowledge, this is the first report of an asymptomatic cilium inside the subconjunctival space. Content Type Journal ArticlePages 1-2DOI 10.1007/s10792-011-9449-5Authors Tatsuya Mimura, Department of Ophthalmology, University of Tokyo Graduate School of Medicine, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655 JapanTakayuki Nakashizuka, Department of Ophthalmology, Toranomon Hospital, Tokyo, JapanJunko K... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4897293 Thu, 02 Jun 2011 06:04:22 +0100 4897293 http://www.medworm.com/index.php?rid=4897295&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy8253442p376n318%2F Content Type Journal ArticlePages 1-2DOI 10.1007/s10792-011-9445-9Authors Parag K. Shah, Department of Pediatric Retina & Ocular Oncology, Aravind Eye Hospital & Postgraduate Institute of Ophthalmology, Avinashi Road, Coimbatore, 641 014 Tamil Nadu, IndiaV. Narendran, Department of Pediatric Retina & Ocular Oncology, Aravind Eye Hospital & Postgraduate Institute of Ophthalmology, Avinashi Road, Coimbatore, 641 014 Tamil Nadu, IndiaN. Kalpana, Department of Pediatric Retina & Ocular Oncology, Aravind Eye Hospital & Postgraduate Institute of Ophthalmology, Avinashi Road, Coimbatore, 641 014 Tamil Nadu, India Journal International OphthalmologyOnline ISSN 1573-2630Print ISSN 0165-5701 (Source: International Ophthalmology) International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4897295 Mon, 30 May 2011 17:09:33 +0100 4897295 http://www.medworm.com/index.php?rid=4897294&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F01060v47170p2737%2F Abstract  To report a case of late diagnosis of a classical familial homocystinuria based on an ophthalmologic examination. A 35-year-old male with Marfan-like phenotype complained of a progressive increase of myopia during the previous 2 years. Ophthalmologic exploration showed a bilateral subluxation of the lens with inferior and nasal displacement. Biochemical study detected a profile of increased amino acid levels (homocysteinemia) consistent with suspected homocystinuria. Vascular and skeletal studies ruled out Marfan syndrome. Response to treatment demonstrated B6-non-responsive homocystinuria. Molecular study showed compound heterozygous T353 N and D444 N mutations of the cystathionine beta-synthase (CBS) gene, and also a C667T homozygous mutation of th... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4897294 Mon, 30 May 2011 17:09:33 +0100 4897294 http://www.medworm.com/index.php?rid=4897296&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F7082n2737x652625%2F We report three subjects of a Greek family affected by triple A syndrome (AAAS). All patients underwent complete ophthalmic examination, full-field electroretinogram (ERG), visual evoked responses (VER), optical coherence tomography (OCT) and molecular analysis of the AAA gene. All patients had alacrima. In two of them, the proband and her brother, bilateral optic atrophy was assessed and the VER were pathological. In contrast, the ERG was normal. OCT showed a decrease of the retinal nerve fiber layer. The third case had only alacrima and the optic nerves were normal. The molecular genetic study of the AAAS gene revealed a homozygous missense mutation p.Ala167Val. To our knowledge this is the first time a family with AAAS has been investigated using OCT, VER and ERG. Our findings illu... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4897296 Mon, 30 May 2011 17:09:31 +0100 4897296 http://www.medworm.com/index.php?rid=4897297&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fvrv34243v2384u85%2F We report on a 74-year-old woman who presented with HZ optic neuritis 45 days after developing an incompletely treated bout of trigeminal HZ, characterized only by pruritus. It is important to value the non-specific manifestations of cutaneous HZ in the prodromal phase, so as to offer timely and appropriate treatment. Content Type Journal ArticlePages 1-4DOI 10.1007/s10792-011-9443-yAuthors Breno de Mello Vitor, Resident of the Centro Oftalmológico de Minas Gerais, Rua Santa Catarina 941, Bairro: Lourdes, Cep 30170-081 Belo Horizonte, Minas Gerais, BrazilEmílio Castelar Macedo Foureaux, Ophthalmologist of the Centro Oftalmológico de Minas Gerais, Belo Horizonte, BrazilFernanda Belga Ottoni Porto, Department of Retina and Vitreous, Centro Oftalmológico de Minas Gerais, Be... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4897297 Fri, 27 May 2011 18:14:58 +0100 4897297 http://www.medworm.com/index.php?rid=4897298&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F4n432u6222084102%2F Abstract  A 70-year-old male was referred to the oculoplastic clinic with left-sided ptosis and floppy eyelids. During follow-up, bilateral upper lid xanthelasma developed with worsening ptosis and proptosis, which was worse on the left side. A left orbital biopsy showed xanthogranulomatous inflammation of the orbit. The patient was treated with a variety of immune modulator regimes but due to a variety of side-effects, treatment was discontinued. The left orbit was surgically debulked twice and histology revealed xanthogranulomatous inflammation, with the additional features of sclerosis, lymphoid aggregates and a prominent population of plasma cells. Around 80% of the plasma cells expressed immunoglobulin G4 (IgG4). This case report reveals an association between xanthogr... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4897298 Fri, 27 May 2011 18:14:57 +0100 4897298 http://www.medworm.com/index.php?rid=4897299&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F68352h5122n50103%2F Abstract  To report three cases with sustained ocular hypertension following intravitreal injections of 0.5 mg/0.05 ml ranibizumab and to underline the importance of monitoring intraocular pressure (IOP) following intravitreal injections of ranibizumab (Lucentis). Three patients were found to have high IOP after intravitreal injections of 0.5 mg/0.05 ml ranibizumab. IOP was elevated after the second ranibizumab injection in patients 1 and 2, and after the third injection in patient 3. The increase in IOP was sustained, requiring treatment with anti-glaucoma eye drops in all patients, the addition of systemic carbonic anhydrase inhibitor in one patient, and the application of selective laser trabeculoplasty (SLT) in another patient. None of the patients ha... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4897299 Wed, 25 May 2011 06:17:27 +0100 4897299 http://www.medworm.com/index.php?rid=4666576&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd05553q1n5250546%2F Abstract  To describe the epidemiological and laboratory characteristics of microbial keratitis at a referral center in Brazil. Charts of all patients referred to the Ocular Microbiology Laboratory at Federal University of São Paulo (UNIFESP) from July 1975 to September 2007 were retrospectively reviewed. The following data were recorded: age, gender, involved eye, use of ocular medication, previous trauma or surgery, contact lens wear and the results of laboratory cultures. The study included 6,804 corneal cultures. The mean age was 42.1 ± 21.4 years. The male-to-female ratio was 1.5:1. Positive cultures were obtained in 3,309 (48.6%) cases. Of these, bacteria were isolated in 2,699 (39.7%), fungi in 364 (5.3%) and Acanthamoeba in 246 (3.6%) samples. Positi... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4666576 Wed, 30 Mar 2011 05:50:13 +0100 4666576 http://www.medworm.com/index.php?rid=4646979&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb24x785783r4v251%2F Abstract  The aim of this study was to examine long-term changes of laser flare (LF) after trabeculectomy (TE) and transscleral diode cyclophotocoagulation (TDCPC) in patients with uveitic secondary glaucoma. Retrospective, single-center analysis. Overall, 40 TE (mean follow-up 21.1 months) and 68 TDCPC (mean follow-up 21.8 months, P = 0.38) procedures were performed. The intraocular pressure (IOP) level was consistently lower in the TE group at the preoperative visit and at each follow-up visit, while IOP reduction was similar in both groups (P = 0.91). LF decreased from 59.4 photons/ms at baseline to 41.9 photons/ms in the TE group (P = 0.017) and remained unchanged in the TDCPC group (71.2 vs. 70.7 photons/ms, P = 0.84). No ... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4646979 Fri, 25 Mar 2011 05:50:34 +0100 4646979 http://www.medworm.com/index.php?rid=4646980&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F3541844j5107123u%2F Abstract  To evaluate the role of intravitreal bevacizumab in the treatment of Coats’ disease diagnosed in adulthood. Prospective, interventional case series. Three patients with Coats’ disease diagnosed in adulthood were managed with a single intravitreal injection of bevacizumab (1.25 mg) with peripheral laser photocoagulation 3 weeks later. All three patients had exudation at the macula (Stage 2B) along with peripheral retinal telangiectasia and aneurysms. They were followed up for 9 months. An appreciable reduction in the exudation at the macula and macular edema was observed in all cases following intravitreal bevacizumab therapy. In all patients, the visual acuity improved, and no signs of recurrence were observed at the final follow-up at 9 mon... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4646980 Fri, 25 Mar 2011 05:50:33 +0100 4646980 http://www.medworm.com/index.php?rid=4628537&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd288908044k34263%2F We report the short term anatomical and functional outcomes of the Boston type 1 keratoprosthesis for severe bilaterally blinding vernal keratoconjunctivitis and Mooren’s ulcer. A retrospective chart review was conducted of 2 patients who underwent several unsuccessful ocular surface reconstruction procedures before Boston type 1 keratoprosthesis implantation. The anatomical and visual outcomes of the Boston type 1 keratoprosthesis at 1 year of follow-up were assessed clinically and by anterior segment optical coherence tomography imaging. The keratoprosthesis was retained in both the eyes at 1 year postoperatively with a best-corrected visual acuity of 20/30 in both patients. To our knowledge this is the first report of successful Boston keratoprosthesis implantation for... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4628537 Tue, 22 Mar 2011 06:05:35 +0100 4628537 http://www.medworm.com/index.php?rid=4618180&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff00x1413324g1154%2F Abstract  Cataracta membranacea (CM) is a rare condition characterized by the remnants of lens capsules and fibrous proliferation that develops secondary to lens matter liquefaction and absorption. Although CM is usually bilateral and may be associated with other congenital anomalies and poor visual prognosis; it can rarely be seen in the adults with involvement of only one eye. Reported herein, is a case of 57-year-old man who presented with CM in his right eye and underwent successful in-the-bag intraocular lens implantation with good visual outcome. Content Type Journal ArticlePages 1-3DOI 10.1007/s10792-011-9437-9Authors Pawan Prasher, Department of Ophthalmology, Sri Guru Ram Das Institute of Medical Sciences and Research, Vallah, Amritsar, Punjab India Jou... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4618180 Sun, 20 Mar 2011 05:32:28 +0100 4618180 http://www.medworm.com/index.php?rid=4618181&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F7532n618l1n93116%2F Abstract  The aim of this study was to evaluate the usefulness of the RTVue-100 Fourier-domain optical coherence tomograph (RTVue-100 OCT) in screening for glaucoma and non-arteritic anterior ischemic optic neuropathy (NA-AION). In a non-population-based pre-publicised trial, self-recruited Caucasian participants were screened for glaucoma and NA-AION using the RTVue-100 OCT, and also by independent clinical examination. For the RTVue-100 OCT measurements, the optic nerve head (ONH) scan and the macular ganglion cell complex (GCC) scan were applied. Subjects with possible optic neuropathy (as indicated by any of the scans and/or by the clinical examination) underwent a detailed clinical investigation to verify or exclude the disease. Of the 146 attendees, 133 participants (... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4618181 Sat, 19 Mar 2011 16:57:18 +0100 4618181 http://www.medworm.com/index.php?rid=4618182&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fww650677v426mkm5%2F Abstract  Amblyopia is a form of cerebral visual impairment in the absence of an organic cause. It is considered to derive from the degradation of the retinal image associated with abnormal visual experience during the developmental period of the visual system in infancy and early childhood. Amblyopia is a significant cause of unilateral visual deficit in childhood and is still considered as one of the most common causes of persistent unilateral visual impairment in adulthood. The following review aims at presenting the contemporary literature regarding the prevalence, the aetiology, the neural correlates, the period of critical development, the treatment, the prognosis and the disability associated with this visual deficit. Content Type Journal ArticlePages 1-8DOI 10.1... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4618182 Sat, 19 Mar 2011 16:57:16 +0100 4618182 http://www.medworm.com/index.php?rid=4618183&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd033683jh883472w%2F The objective of this survey was to evaluate the type, dose, frequency and duration of drops used in all centres (n = 117) participating in the acute myeloid leukaemia trial 15 (AML 15), and to assess adherence to the trial protocol prescribed guidelines. All centres used prophylactic treatment; however, the dose of Ara-C at which it was initiated varied from 100 to 6000 mg/m2/day. All centres used some form of steroid prophylaxis with prednisolone 0.5% being the most commonly used (98/117), but only 6 of the 117 centres initiated treatment at doses recommended in the trial protocol. Ten centres used lubricants in addition to steroids. No centre reported the use of non-steroidal anti-inflammatory drops. The duration of treatment ranged from 2 days prior to commenc... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4618183 Sat, 19 Mar 2011 02:52:04 +0100 4618183 http://www.medworm.com/index.php?rid=4576114&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F06570384128617vu%2F In this report, the risk factors and the likely pathogenesis for such an event are studied. Content Type Journal ArticlePages 1-3DOI 10.1007/s10792-011-9427-yAuthors Malavika Subash, Moorfields Eye Hospital, London, EC1V 2PD UKKamaljit S. Balaggan, Moorfields Eye Hospital, London, EC1V 2PD UKHadi J. Zambarakji, Whipps Cross University Hospital, London, E11 1NR UK Journal International OphthalmologyOnline ISSN 1573-2630Print ISSN 0165-5701 (Source: International Ophthalmology) International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4576114 Wed, 09 Mar 2011 16:50:34 +0100 4576114 http://www.medworm.com/index.php?rid=4499062&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F95696764641h4230%2F Abstract  To report the changes seen in the photoreceptor layer during the acute phase of sympathetic ophthalmia. Six consecutive patients diagnosed with sympathetic ophthalmia were enrolled in the study. All 6 patients had a fundus fluorescein angiogram and spectral domain optical coherence tomography (OCT) scan carried out at presentation. The outer retinal segment was demarcated on the raster line scan between the external limiting membrane (ELM) and the retinal pigment epithelium (RPE)–choriocapillaris complex. All patients received intravenous methylprednisolone followed by oral corticosteroids 1–1.5 mg/kg/day. The serial follow-up OCT scans taken 48 h after the initiation of treatment, and 1, 2 and 12 weeks later, were studied and compared. The retin... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4499062 Fri, 18 Feb 2011 06:51:12 +0100 4499062 http://www.medworm.com/index.php?rid=4491655&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr252227g3844178r%2F Abstract  Diagnosis of corneal intraepithelial neoplasia was missed in a patient who presented with recurrent large epithelial defects with pannus. The patient was eventually diagnosed and successfully treated with topical mitomycin C. Mitomycin C may be preferable to surgery in lesions with extensive corneal involvement. Impression cytology should be used for early diagnosis in suspicious lesions. Content Type Journal ArticlePages 1-3DOI 10.1007/s10792-011-9431-2Authors Nikhil S. Gokhale, Gokhale Eye Hospital and Eyebank, Anant building, Gokhale Road (S), Dadar West, Mumbai, 400 028 India Journal International OphthalmologyOnline ISSN 1573-2630Print ISSN 0165-5701 (Source: International Ophthalmology) International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4491655 Wed, 16 Feb 2011 07:09:19 +0100 4491655 http://www.medworm.com/index.php?rid=4491654&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2661575w4r458280%2F We describe the case of a healthy, pregnant female who developed endogenous endophthalmitis at the time of delivery, and discuss the possible mechanism of infection and the management of this case. A 26-year-old Asian woman presented with a 3-week history of visual deterioration and pain in the right eye. There was no history of ocular trauma or surgery. The ocular symptoms developed one day after vaginal delivery of a healthy baby. The pregnancy had been uncomplicated until premature rupture of membranes one week prior to delivery. Right visual acuity was light perception. There was marked right anterior chamber activity with a hypopyon and fibrin. A B-scan ultrasound showed dense vitritis. Examination of the left eye was normal. Blood tests and a chest X-ray were normal. A vitreous... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4491654 Wed, 16 Feb 2011 07:09:19 +0100 4491654 http://www.medworm.com/index.php?rid=4440001&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F6122106858163771%2F Abstract  To study the functional recovery of a patient with cerebrovascular injury using combined functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI). A 24-year-old woman with left hemianopsia underwent fMRI and DTI in a 1.5-tesla machine both in the acute phase and 1 month after an ischaemic stroke involving the right calcarine cortex. Acute-phase fMRI demonstrated that peripheral left visual field stimulation did not activate the right primary visual cortex, whereas stimulation 1 month later activated the visual cortex bilaterally. Analysis of acute-phase DTI data disclosed that a reduction of fractional anisotropy in the right optic radiation had almost resolved after 1 month. Fibre direction was normal at either time point. fM... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4440001 Fri, 04 Feb 2011 09:21:58 +0100 4440001 http://www.medworm.com/index.php?rid=4440002&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F828385483w6vj53q%2F Abstract  Tumor necrosis factor alpha (TNF-α) is a key soluble mediator involved in the inflammatory cascade of many disorders including uveitis. Among the anti-TNF-α agents, one of the most used in immune-mediated diseases, such as inflammatory arthropathies, is adalimumab (Humira™, Abbott Pharmaceutical Inc.), a fully humanized antibody. The purpose of this review is to analyze the main pharmacological and clinical aspects of adalimumab and its efficacy both in systemic and ocular inflammatory disorders. Adalimumab was effective in treating several autoimmune diseases, such as rheumatoid arthritis, ankylosing spondylitis, and psoriatic arthritis. In recent years, adalimumab has been used successfully in refractory cases of intraocular inflammation. Moreover, this biolo... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4440002 Thu, 03 Feb 2011 07:24:15 +0100 4440002 http://www.medworm.com/index.php?rid=4430401&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F0r7u2885146541j3%2F Content Type Journal ArticlePages 1-2DOI 10.1007/s10792-011-9418-zAuthors Sunita Chaurasia, Cornea and Anterior Segment Service, L V Prasad Eye Institute, L V Prasad Marg, Banjara Hills, Hyderabad, 500 034 IndiaR. Muralidhar, Cornea and Anterior Segment Service, L V Prasad Eye Institute, L V Prasad Marg, Banjara Hills, Hyderabad, 500 034 India Journal International OphthalmologyOnline ISSN 1573-2630Print ISSN 0165-5701 (Source: International Ophthalmology) International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4430401 Tue, 01 Feb 2011 08:46:12 +0100 4430401 http://www.medworm.com/index.php?rid=4430402&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe1p470671582n441%2F We describe a case of anterior capsular contraction syndrome following uneventful surgery and without any known predisposing factors. Content Type Journal ArticlePages 1-3DOI 10.1007/s10792-011-9425-0Authors Archana Malik, Department of Ophthalmology, Government Medical College Hospital, Sector- 32, Chandigarh, IndiaNeeti Gupta, Department of Ophthalmology, Government Medical College Hospital, Sector- 32, Chandigarh, IndiaSunandan Sood, Department of Ophthalmology, Government Medical College Hospital, Sector- 32, Chandigarh, India Journal International OphthalmologyOnline ISSN 1573-2630Print ISSN 0165-5701 (Source: International Ophthalmology) International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4430402 Sat, 29 Jan 2011 06:49:53 +0100 4430402 http://www.medworm.com/index.php?rid=4430403&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm67107p2w1513r51%2F We report on a case of extensive unilateral visual field loss due to a peripapillary arteriovenous communication. Interventional case report. A 27-year-old Caucasian woman who was initially managed for retrobulbar optic neuritis underwent fundus fluorescein angiography (FFA) and indocyanine green angiography (ICGA) 6 months later that revealed an unusual course of the central retinal vein with focal dilatation and co-existent aneurysmal distention of the adjacent large choroidal vein. Subsequent colour Doppler flow imaging of the dilated area confirmed the existence of arterial flow suggesting a “vascular steal” phenomenon resulting in choroidal and optic disc ischaemia. Brain magnetic resonance imaging (MRI) revealed small focal capillary vessel abnormalities in the parieta... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4430403 Sat, 29 Jan 2011 06:49:52 +0100 4430403 http://www.medworm.com/index.php?rid=4430404&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg501231175n1k734%2F Abstract  The aim of our study was to report on the incidence, the etiology and the management of intraoperative floppy iris syndrome (IFIS) during phacoemulsification. A non-randomized, observational, prospective study was performed for 1 year, in which 439 eyes of 438 patients (320 men and 118 women) undergoing cataract surgery by the same surgeon were enrolled. The surgeon was blinded to the patients’ drug history. The use or non-use of alpha blockers (especially tamsulosin for benign prostatic hyperplasia), duration of the treatment, presence or absence of IFIS, management of IFIS and intraoperative complications were recorded. A 3.2 mm incision was performed on 316 eyes and a 2.4 mm incision on 123 eyes. IFIS occurred in 2.96% of the patients who were ... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4430404 Fri, 28 Jan 2011 20:33:15 +0100 4430404 http://www.medworm.com/index.php?rid=4430405&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr95j2p4h625227l5%2F Abstract  To report on our initial experience screening for diabetic retinopathy (DR) usingdigital fundus photography and standarized criteria. Cross-sectional prospective study of all 1327 diabetic patients referred to the Ophthalmology Department of the Clorito Picado Clinic in San José, Costa Rica between April 2008 and March 2009. Patients were screened with a single-field 45-degree digital color retinal image centered on the fovea. The main outcome measures were prevalence of DR, waiting time for a fundus photograph appointment and the number of patients that needed to be evaluated by an ophthalmologist. In this population of 1327 patients, 85% did not have any retinopathy. The prevalence of DR was 15%. Mild non-proliferative DR (NPDR) was seen in 5.8% (70/1215), mode... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4430405 Fri, 28 Jan 2011 06:54:06 +0100 4430405 http://www.medworm.com/index.php?rid=4416176&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F35536406m8l2512m%2F Abstract  To analyze the characteristics and treatment outcomes of pediatric orbital dermoid cysts. Chart review of consecutive pediatric biopsy-proven dermoid cysts surgically removed at the Department of Ophthalmology, Maggiore Hospital, between 2000 and 2007. We excised dermoid cysts from 30 children (30 eyes) whose mean age at the time of surgery was 24 months (range 6−84). The most common presentation of the cyst was a palpable or partially palpable mass (100%), followed by a superior lid ptosis (10%). Twenty patients (67%) had superficial cysts with margins well-definable by palpation, and 10 patients (33%) had deep cysts that extended beyond the orbital rim with an incomplete palpation of margins requiring imaging studies. The most frequent localization of the cyst... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4416176 Wed, 26 Jan 2011 19:47:07 +0100 4416176 http://www.medworm.com/index.php?rid=4416175&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fbug3714724234q2t%2F We report on 2 patients with unusual retinal manifestations of cat scratch disease (CSD), caused by Bartonella henselae. Case 1. A 42-year-old farmer presented with a 5-day history of blurred vision in his right eye. Right visual acuity was 20/25. Fundus examination of the right eye revealed mild vitreous hemorrhage and diffuse retinal hemorrhages in the mid-peripheral retina. Fluorescein angiography showed multiple vasculitic occlusions in the same area. A blood sample taken on the day of examination revealed the presence of immunoglobulin (Ig)M and IgG to B. henselae. Oral azithromycin was given for 8 days. One month later, right visual acuity was 20/20, the vitreous and retinal hemorrhages resolved, and arteriolar attenuation and sclerosis was observed in the peripheral tempora... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4416175 Wed, 26 Jan 2011 19:47:07 +0100 4416175 http://www.medworm.com/index.php?rid=4416178&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2175859577476445%2F We report a case involving bilateral posterior ischemic optic neuropathy with Behçet’s disease in a 49-year-old woman. The patient presented because of abrupt visual disturbances. An ophthalmic examination, including fluorescein angiography, visual field testing, and visual-evoked potentials, was performed. Her visual acuity was 20/100 bilaterally and posterior ischemic optic neuropathy was suspected. She was treated with systemic methylprednisolone; however, disc pallor developed and the visual acuity remained 20/200 bilaterally. Optic neuropathy can be bilateral, affect both eyes simultaneously, and lead to severe visual loss despite high doses of systemic steroid treatment. Optic neuropathy in Behçet’s disease is very rare. This case provides clinical insight into the neuro-... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4416178 Wed, 26 Jan 2011 19:47:05 +0100 4416178 http://www.medworm.com/index.php?rid=4416177&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj2h864010601x396%2F Abstract  To assess the visual function of patients with keratoconus who underwent penetrating keratoplasty with the use of the VF-14 questionnaire. Fourteen patients (9 male and 5 female) with a mean age of 38 years (SD 13.59) participated in the study. All patients had keratoconus, confirmed by corneal topography, and all had previously undergone penetrating keratoplasty in one eye. Their mean best-corrected visual acuity (BCVA) binocularly was 0.185 (SD 0.077) LogMAR. None of the grafted eyes had a BCVA <0.300 LogMAR. Fourteen healthy volunteers, age- and sex-matched, also participated in the study as control subjects. The VF-14 questionnaire was used to evaluate the effect of the ocular status in the daily life activities of the patients. The mean VF-14 result f... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4416177 Wed, 26 Jan 2011 19:47:05 +0100 4416177 http://www.medworm.com/index.php?rid=4416179&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg784877750253230%2F We describe a patient who presented to us with typical moniliform blepharosis. A brief description of relevance to the ophthalmologist and review of the literature follows. Content Type Journal ArticlePages 1-3DOI 10.1007/s10792-011-9417-0Authors Monal P. Sainani, Aravind Eye Hospital, Madurai, IndiaR. Muralidhar, Aravind Eye Hospital, Madurai, IndiaK. Parthiban, Aravind Eye Hospital, Madurai, IndiaP. Vijayalakshmi, Aravind Eye Hospital, Madurai, India Journal International OphthalmologyOnline ISSN 1573-2630Print ISSN 0165-5701 (Source: International Ophthalmology) International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4416179 Wed, 26 Jan 2011 19:47:03 +0100 4416179 http://www.medworm.com/index.php?rid=4412774&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F1q374l0241662674%2F Abstract  To report two unusual cases of endogenous endophthalmitis associated with liver abscess caused by Klebsiella pneumoniae. Retrospective, interventional case series. Two patients, known to have type II diabetes mellitus, presented with sudden visual loss following several days of abdominal pain. Examinations and investigations revealed endogenous endophthalmitis caused by K. pneumoniae. Despite treatment in the form of intravitreal injection of antibiotics in the first patient and pars plana vitrectomy coupled with intravitreal injection of antibiotics in the second patient the final visual outcome was poor in both cases. The possibility of K. pneumoniae endogenous endophthalmitis should be suspected in diabetic patients presenting with intraocular inflammation. ... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4412774 Tue, 25 Jan 2011 06:43:54 +0100 4412774 http://www.medworm.com/index.php?rid=4412773&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F148302h4034k5884%2F We report a case of isolated foveal hypoplasia where the underlying genetic cause could not be established. We could not rule out other genetic or epigenetic factors contributing to the pathogenesis of isolated foveal hypoplasia. Content Type Journal ArticlePages 1-4DOI 10.1007/s10792-011-9424-1Authors Ahmed A. Al-Saleh, AlHokama Eye Specialist Center, Riyadh, Saudi ArabiaAli Hellani, The PGD Laboratory, Saad Specialist Hospital, Al-Khobar, Saudi ArabiaKhaled K. Abu-Amero, The Ophthalmic Genetics Laboratory, Department of Ophthalmology, College of Medicine, King Saud University, P.O. Box 245, 11411 Riyadh, Saudi Arabia Journal International OphthalmologyOnline ISSN 1573-2630Print ISSN 0165-5701 (Source: International Ophthalmology) International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4412773 Tue, 25 Jan 2011 06:43:54 +0100 4412773 http://www.medworm.com/index.php?rid=4412772&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh014566525484482%2F We report a case of peripheral ulcerative keratitis associated with neutrophilic dermatosis of the dorsal hand, a recently described clinical entity. A 68-year-old man presented with concurrent peripheral ulcerative keratitis of the right eye and neutrophilic dermatosis of the dorsal hand causing pustular skin eruptions on the dorsal surface of both hands. Systemic investigations suggested an underlying diagnosis of Wegener’s granulomatosis. To our knowledge this is the first reported case of neutrophilic dermatosis of the dorsal hand associated with ocular complications. Content Type Journal ArticlePages 1-3DOI 10.1007/s10792-011-9428-xAuthors James Benzimra, Ophthalmology Department, Musgrove Park Hospital, Taunton, TA1 5DA Somerset UKJacob Low-Beer, Ophthalmology Department... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4412772 Tue, 25 Jan 2011 06:43:54 +0100 4412772 http://www.medworm.com/index.php?rid=4412771&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh5831g4501732372%2F Abstract  A 57-year-old male with a 1-year history of recurrent oral ulceration and papulopustular lesions presented with acute visual loss in his left eye. He had an oedematous disc without any signs of uveitis. Laboratory work-up regarding infectious diseases was negative. The patient was diagnosed with acute optic neuropathy secondary to Behçet’s disease. Systemic steroid and colchicine treatments were started but his vision did not improve. Isolated optic neuropathy is rare in Behçet’s disease and early treatment with high-dose steroids may not be successful in some cases. Content Type Journal ArticlePages 1-3DOI 10.1007/s10792-011-9416-1Authors Ebru N. Çetin, Department of Ophthalmology, Pamukkale Üniversitesi, Göz Hastalıkları AD, Kınıklı Kampüsü,... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4412771 Tue, 25 Jan 2011 06:43:54 +0100 4412771 http://www.medworm.com/index.php?rid=4302538&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Feph11114407x28t3%2F Abstract  To determine the relationship between visual acuity and three-dimensional optical coherence tomographic (3D-OCT) findings of the macula in eyes with Vogt–Koyanagi–Harada (VKH) disease. Twelve eyes of six patients (three men and three woman, average age 53.2 years) in the acute phase of VKH disease were examined with a 3D-OCT instrument. All of the eyes had a serous macular detachment. The height of the sensory retinal detachment (SRD) and the sensory retinal thickness (SRT) were measured by OCT before treatment (acute stage) and at the convalescent stage. The correlation between the retinal morphology and visual acuity was evaluated. The height of the SRD and the SRT were 612.5 ± 371.2 and 136. 7 ± 22.0 μm, respectively. The ini... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4302538 Thu, 30 Dec 2010 18:04:00 +0100 4302538 http://www.medworm.com/index.php?rid=4302537&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx812666516l05840%2F Abstract  The purpose of this study was to compare the structural outcome of laser treatment to avascular retina and ridge versus laser treatment to avascular retina alone in cases with threshold retinopathy of prematurity (ROP). A prospective, randomized, interventional, comparative study of consecutive cases referred to a single tertiary center was considered here. 50 infants with bilateral symmetrical threshold ROP were recruited into this study over a period of 3 years. Threshold ROP was defined as per CRYO-ROP study. Perinatal history details for all patients including significant maternal history were recorded. One eye of each patient was randomized (Microsoft Excel 2000) to one of the two treatment groups—laser treatment to avascular retina (Group A) or laser ... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4302537 Thu, 30 Dec 2010 18:04:00 +0100 4302537 http://www.medworm.com/index.php?rid=4112701&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk7321428436748t8%2F Content Type Journal ArticleDOI 10.1007/s10792-010-9409-5Authors Carl P. Herbort, Centre for Ophthalmic Specialised Care (COS), Lausanne, SwitzerlandPhilippe Kestelyn, Department of Ophthalmology, University of Gent, Gent, Belgium Journal International OphthalmologyOnline ISSN 1573-2630Print ISSN 0165-5701 (Source: International Ophthalmology) International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4112701 Mon, 25 Oct 2010 16:58:42 +0100 4112701 http://www.medworm.com/index.php?rid=4112702&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F973k5077w231j77m%2F Content Type Journal ArticleDOI 10.1007/s10792-010-9405-9Authors Colin S. H. Tan, Department of Ophthalmology, Tan Tock Seng Hospital, Singapore, SingaporeRengaraj Venkatesh, Aravind Eye Hospital, Pondicherry, India Journal International OphthalmologyOnline ISSN 1573-2630Print ISSN 0165-5701 (Source: International Ophthalmology) International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4112702 Sat, 23 Oct 2010 05:44:54 +0100 4112702 http://www.medworm.com/index.php?rid=4092031&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd013v0065562r971%2F We present a novel finding of juxtafoveal choroidal neovascularisation in Bietti crystalline dystrophy and demonstrate a spectral domain optical coherence tomography image of this disorder. Content Type Journal ArticleDOI 10.1007/s10792-010-9406-8Authors B. Gupta, St. Thomas’ Hospital, Lambeth Palace Road, London, SE1 7EH UKS. Parvizi, St. Thomas’ Hospital, Lambeth Palace Road, London, SE1 7EH UKM. D. Mohamed, St. Thomas’ Hospital, Lambeth Palace Road, London, SE1 7EH UK Journal International OphthalmologyOnline ISSN 1573-2630Print ISSN 0165-5701 (Source: International Ophthalmology) International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4092031 Fri, 22 Oct 2010 18:27:03 +0100 4092031 http://www.medworm.com/index.php?rid=4092032&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ffl47n05n77948lgv%2F Abstract  Paracoccidioidomycosis (PCM) is the most prevalent systemic mycosis in immunocompetent individuals in Brazil. Ocular infection by PCM is rare; however, when infection does occur, the most common ocular sites involved are eyelid and conjunctiva. A 68-year-old white male presented with a 2-month history of a painless, ulcerated, infiltrative and diffuse whitish lesion located on the right inferior eyelid. A clinical diagnosis of malignant tumor, possibly squamous cell carcinoma, was made. The histopathologic examination showed a hyperplastic epithelium with inflammatory infiltrate of lymphocytes, plasma cells, neutrophils and histiocytes. Large numbers of giant cells were also present. Periodic acid Schiff and Grocott (silver methenamine) stains showed several large... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4092032 Fri, 22 Oct 2010 06:04:10 +0100 4092032 http://www.medworm.com/index.php?rid=4070173&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft200063m6682374j%2F Abstract  Isolated cranial mononeuropathies in patients over 50 years of age most commonly result from microvascular ischemic demyelination. A 51-year-old female without vasculopathic risk factors presented with isolated sixth nerve palsy. Magnetic resonance imaging (MRI) of the brain and orbits revealed a cavernous sinus lesion that was diagnosed as a meningioma. Laboratory tests showed abnormal liver function, and an abdominal computerized tomogram demonstrated an obstructive colonic mass with liver metastasis. The pathology tests of specimens taken during a laparotomy diagnosed colon adenocarcinoma. The MRI interpretation was changed to cavernous sinus metastasis from a primary adenocarcinoma of the colon. This case had common cranial nerve symptoms but with a very ... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4070173 Tue, 12 Oct 2010 16:50:10 +0100 4070173 http://www.medworm.com/index.php?rid=4063196&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb3103l20895882w7%2F Abstract  To evaluate the effectiveness of an intravitreal bevacizumab injection on retinal neovascularization and diabetic macular edema (DME) refractory to laser photocoagulation therapy. Thirty-four eyes of 22 patients with proliferative diabetic retinopathy and DME refractory to laser photocoagulation therapy received an intravitreal injection of 1.25 mg/0.05 ml of bevazicumab. Changes in mean best-corrected visual acuity (BCVA), central macular thickness (CMT), regression of neovascularization over time, and correlation between BCVA and CMT were evaluated. Follow-up visits were at weeks 1, 2 and 4 and months 3 and 6. Mean BCVA was significantly better than baseline only at week 2 (P = 0.036). Mean CMT decreased significantly from baseline at weeks 1,... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4063196 Sat, 09 Oct 2010 16:48:57 +0100 4063196 http://www.medworm.com/index.php?rid=4052238&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F621600h36026l361%2F We report the case of an immunocompetent 78-year-old woman who developed cytomegalovirus (CMV) retinitis after a single intravitreous injection of triamcinolone acetonide (IVTA). Review of medical records. The patient with macular edema secondary to branch retinal vein occlusion developed peripheral retinitis with hemorrhagic and inflammatory vascular sheathing 3 months after IVTA. A presumptive diagnosis of viral retinitis was confirmed by polymerase chain reaction (PCR) of the aqueous humor tap. The PCR test was positive for CMV DNA. The patient slowly responded to intravenous ganciclovir and oral valganciclovir. After therapeutic vitrectomy for intercurrent vitreous hemorrhage, and while still under treatment, the retinitis resolved completely with final visual acuity of 20/2... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4052238 Thu, 07 Oct 2010 16:50:43 +0100 4052238 http://www.medworm.com/index.php?rid=4042700&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fjj336x41h2764753%2F Abstract  To test the ability of frequency doubling technology (FDT) perimetry to reveal defects in the same field quadrants as detected by standard automated perimetry (SAP). Ninety-two eyes with open-angle glaucoma and documented visual field defects by threshold SAP (Octopus Dynamic strategy) also underwent threshold FDT testing after successfully passing the FDT screening test. All eyes revealed varying stages of SAP defects while only 80 revealed FDT damage: 31:21 eyes in the early field loss stage, 36:35 in the moderate field loss stage, and 25:24 in the severe field loss stage in SAP versus FDT, respectively. SAP was able to detect abnormalities in 74 and 79% of the superotemporal, and inferotemporal quadrants, respectively, while the corresponding FDT figures were 7... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4042700 Wed, 06 Oct 2010 06:01:45 +0100 4042700 http://www.medworm.com/index.php?rid=4042701&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg408nww645212q32%2F Abstract  Although the incidence of ocular trauma has been clearly described in developed countries, few published data are available on the epidemiology and the effects of parameters that can influence the incidence and severity of ocular injuries in Iran. The present study tried to determine epidemiological aspects of ocular traumatic injuries and evaluate their effects on different types of ocular injury. The case series included 1950 consecutive patients with acute ophthalmic trauma presented to the emergency ward of Farabi Hospital in Tehran. Information was collected by interviewing patients and having them fill in a questionnaire. The final diagnosis was made by a medical resident. If there was a difficulty or doubt in diagnosis or classification, confirmation of dia... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4042701 Tue, 05 Oct 2010 18:05:46 +0100 4042701 http://www.medworm.com/index.php?rid=4038534&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq2r2762005446342%2F Abstract  To describe a congenital retinal macrovessel with macular thickening. This case was investigated using fundus photography, fluorescein angiography, Spectralis optical coherence tomography and a 10–2 visual field test. A 23-year-old man was referred to our clinic with decreased vision in the right eye. Fundus examination of the right eye revealed a congenital retinal macrovessel that originated inferior to the superotemporal branch of the central retinal vein. Using fluorescein angiography, early filling and delayed emptying of the aberrant vein were observed. Spectralis optical coherence tomography demonstrated macular thickening and was supported by a 10–2 visual field test that revealed a relative scotoma corresponding to the same location. At the 18-month f... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4038534 Mon, 04 Oct 2010 14:47:59 +0100 4038534 http://www.medworm.com/index.php?rid=4020315&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F76m3448356g1k820%2F We present histopathological features that distinguish this tumour from malignant tumours with a basaloid pattern. We also discuss the management differences associated with basaloid patterns in lacrimal tumours. Content Type Journal ArticleDOI 10.1007/s10792-010-9392-xAuthors Jonathan E. Silbert, The Eye Care Group, 40–60 Temple Street, Suite 5-B, New Haven, CT 06510-2715, USAPuneet Braich, Ross University School of Medicine, Dominica, West IndiesRaghunath P. Misra, Department of Ophthalmology, Louisiana State University Health Sciences Center, 1501 Kings Highway, P.O. Box 33932, Shreveport, LA 71130, USA Journal International OphthalmologyOnline ISSN 1573-2630Print ISSN 0165-5701 (Source: International Ophthalmology) International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4020315 Tue, 28 Sep 2010 19:19:10 +0100 4020315 http://www.medworm.com/index.php?rid=4000120&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm012767040244101%2F Abstract  A prospective, non-randomized, comparative study was carried out to investigate aqueous humor and serum erythropoietin (EPO) levels in patients with pseudoexfoliation syndrome (PXS), pseudoexfoliative glaucoma (PXG), and, as controls, senile cataract without glaucoma. Aqueous humor was aspirated at the beginning of cataract or combined glaucoma–cataract surgery from 24 patients with PXS, 24 patients with PXG, and 24 patients with cataract only. Venous blood samples were obtained from all patients at the same time. Levels of EPO were measured in aqueous humor and venous blood using a sandwich enzyme-linked immunosorbent assay (ELISA) kit. There was no statistically significant difference between the mean aqueous humor EPO concentrations in eyes with PXS (10.70&nb... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4000120 Thu, 23 Sep 2010 05:46:41 +0100 4000120 http://www.medworm.com/index.php?rid=4000121&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fvm5652405774q527%2F Conclusion Treatment of KC with PKP or DALK is associated with similar visual outcomes, graft survival, and prevalence of sight-threatening complications. Content Type Journal ArticleDOI 10.1007/s10792-010-9393-9Authors Alex W. Cohen, Department of Ophthalmology and Visual Sciences, University of Iowa Carver College of Medicine, University of Iowa Hospitals and Clinics, Pomerantz Family Pavilion, 200 Hawkins Drive, Iowa City, IA 52242-1091, USAKenneth M. Goins, Department of Ophthalmology and Visual Sciences, University of Iowa Carver College of Medicine, University of Iowa Hospitals and Clinics, Pomerantz Family Pavilion, 200 Hawkins Drive, Iowa City, IA 52242-1091, USAJohn E. Sutphin, Department of Ophthalmology and Visual Sciences, University of Iowa Carver College of Medicine, ... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4000121 Thu, 23 Sep 2010 05:46:39 +0100 4000121 http://www.medworm.com/index.php?rid=4000122&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl7574r69404t31w4%2F Abstract  Age-related macular degeneration (AMD) is one of the leading causes of blindness in the developed world. Although effective treatment modalities such as anti-VEGF treatment have been developed for neovascular AMD, there is still no effective treatment for geographical atrophy, and therefore the most cost-effective management of AMD is to start with prevention. This review looks at current evidence on preventive measures targeted at AMD. Modalities reviewed include (1) nutritional supplements such as the Age-Related Eye Disease Study (AREDS) formula, lutein and zeaxanthin, omega-3 fatty acid, and berry extracts, (2) lifestyle modifications, including smoking and body-mass-index, and (3) filtering sunlight, i.e. sunglasses and blue-blocking intraocular lenses. In su... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=4000122 Thu, 23 Sep 2010 05:46:38 +0100 4000122 http://www.medworm.com/index.php?rid=3996224&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr23133509517j31w%2F Abstract  To describe the clinical features and outcomes in patients with herpetic anterior uveitis. We reviewed the records of 111 patients with a clinical diagnosis of herpetic anterior uveitis seen at the Department of Ophthalmology, Istanbul Faculty of Medicine, from January 1996 to December 2006. Demographic and clinical features, recurrence rate, and visual outcome were analyzed. Fifty patients were male, 61 were female. Mean age at presentation was 39.2 ± 16.5 (6–74) years. Three atopic patients had bilateral involvement. Twelve patients had active or a past episode of herpes zoster ophthalmicus. Ocular findings were granulamatous anterior uveitis (93%), active keratitis or corneal scars (57%), elevated intraocular pressure (51%), iris atrophy (48%), dis... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=3996224 Tue, 21 Sep 2010 11:24:10 +0100 3996224 http://www.medworm.com/index.php?rid=3996223&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa7763413k1070409%2F Abstract  An 18-year-old male presented to the ophthalmology department with bilateral total subluxated cataract. On systemic examination, he was found to have grossly short stature, multiple severe bony deformities, hypogonadism and partial adontia. Detailed work-up revealed a biochemical and radiologic picture consistent with osteomalacia, which had resulted from malabsorption secondary to celiac disease, confirmed histopathologically. To the best of our knowledge, this is the first reported case of bilateral cataract as the presenting feature of celiac disease. Malabsorption leading to hypocalcemia along with chronic diarrhea itself may have contributed to the development of bilateral cataract. Content Type Journal ArticleDOI 10.1007/s10792-010-9396-6Authors Usha K... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=3996223 Tue, 21 Sep 2010 11:24:10 +0100 3996223 http://www.medworm.com/index.php?rid=3996225&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu28xt5777tw01178%2F Abstract  The reported shape and size of the vitreous pocket vary depending on the method of visualization. We used spectral domain optical coherence tomography (SD-OCT) to clarify the structure of the normal vitreous pocket. The macular retina of 20 consecutive non-highly myopic eyes of 10 healthy young adults (aged 22−27 years) was examined using spectral SD-OCT. The premacular vitreous pocket and the pre-papillary Cloquet’s canal were observed in a scan area 9 mm in transverse diameter and 6 mm in longitudinal diameter. On SD-OCT, the vitreous pocket was observed in all the eyes, anterior to the macula as a flat dish-like structure measuring 7.5 ± 0.6 mm in transverse diameter, 5.2 ± 0.3 mm in longitudinal diameter, and 0... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=3996225 Mon, 20 Sep 2010 19:59:23 +0100 3996225 http://www.medworm.com/index.php?rid=3996226&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fkv72lx76n64m7532%2F Abstract  This photo essay describes a patient with eyelashes perpendicular to the extruding part of a porous polyethylene orbital implant. The upright position of these eyelashes created the impression of growth on the extruding implant, but they are lost eyelashes that became entrapped in the pores of the implant. Content Type Journal ArticleDOI 10.1007/s10792-010-9395-7Authors Kirsten Robberecht, Unit for Oculoplastic Surgery, Department of Ophthalmology, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, BelgiumLieve Berghmans, Unit for Oculoplastic Surgery, Department of Ophthalmology, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, BelgiumPhilippe Kestelyn, Unit for Oculoplastic Surgery, Department of Ophthalmology, Ghent University Hospital, De Pint... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=3996226 Mon, 20 Sep 2010 19:59:09 +0100 3996226 http://www.medworm.com/index.php?rid=3990396&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw40p32q0570011n0%2F Abstract  A 58-year-old male presented with decreased visual acuity from persistent diffuse diabetic macular edema despite multiple interventions including laser photocoagulation and intravitreal triamcinolone acetonide injections. Following treatment with 1.25 mg of intravitreal bevacizumab, reduction in macular leakage was shown by fluorescein angiography and resolution of edema was shown by optical coherence tomography (OCT); however, visual acuity deteriorated and fluorescein angiograms demonstrated progressive enlargement of the foveal avascular zone (FAZ), which had shown no abnormalities before the injection. Despite normalisation of macular thickness on OCT and cessation of leakage on angiography, visual acuity remained at the same level until 6 months of ... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=3990396 Sat, 18 Sep 2010 05:50:39 +0100 3990396 http://www.medworm.com/index.php?rid=3829740&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj162875p484728vq%2F Abstract  To study the sensitivity of laser flare photometry (LFP) in monitoring anterior chamber inflammation by correlating LFP measurements with slit-lamp evaluation of aqueous cells in HLA-B27-related uveitis in a prospective trial. Slit-lamp cell evaluation was correlated with LFP-measured flare in a masked fashion in HLA-B27-related uveitis patients receiving standard topical therapy. At the time of 50 and 90% LFP flare reduction, the corresponding reduction of cells was recorded and statistically compared using the sign test. Forty-three episodes (in 43 patients) of acute anterior HLA-B27-related uveitis were included. LFP flare reduction and slit-lamp cell reduction were strongly correlated. LFP was significantly more sensitive for both 50% (P = 0.001) and ... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=3829740 Wed, 04 Aug 2010 20:46:49 +0100 3829740 http://www.medworm.com/index.php?rid=3806935&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fet682042256837u1%2F Abstract  Congenital iris ectropion is an uncommon malformation of the anterior segment of the eye. The authors describe a case of bilateral congenital iris ectropion associated with juvenile glaucoma in an otherwise healthy 9-year-old girl. Intra-ocular pressure (IOP) measured by Goldmann applanation tonometry was 40 mmHg in the right eye and 32 mmHg in the left eye. Despite maximum IOP lowering therapy, the desired IOP levels needed to prevent further progression of the glaucoma could not be achieved. Visual field testing and confocal scanning laser tomography showed glaucomatous neuropathy. Trabeculectomy with antimetabolites (mitomycin C 0.2 mg/ml) was performed in both eyes and IOP was normalized without IOP lowering medications during a follow-up of 4&n... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=3806935 Fri, 30 Jul 2010 17:00:22 +0100 3806935 http://www.medworm.com/index.php?rid=3806936&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb30303u7864u3500%2F Abstract  To describe the intra-ocular manifestations of cat-scratch disease (CSD) found at two uveitis reference centers in Brazil. Retrospective case series study. Review of clinical records of patients diagnosed with CSD in the Uveitis Department of São Geraldo Hospital and the Ophthalmology Department of the Instituto de Pesquisa Clínica Evandro Chagas—FIOCRUZ, from 2001 to 2008. In the 8-year period, 24 patients with the diagnosis of CSD were identified. Twelve patients were male and 12 female. The mean age was 27.04 years (range 7–56). Sixteen patients (66.6%) presented with a history of a cat scratch and all patients reported cat exposure. Visual acuity ranged from counting fingers to 1.0 in the affected eye. Thirteen patients presented with bilateral disease. ... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=3806936 Thu, 29 Jul 2010 16:06:38 +0100 3806936 http://www.medworm.com/index.php?rid=3796976&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F4j3u2150qt7742t5%2F Conclusions The present case highlights the potential benefit of early and broad vitrectomy with lensectomy in the management of endogenous K. pneumoniae endophthalmitis. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s10792-010-9387-7Authors Kotaro Ishii, University of Tsukuba Department of Ophthalmology, Institute of Clinical Medicine Ibaraki JapanTakahiro Hiraoka, University of Tsukuba Department of Ophthalmology, Institute of Clinical Medicine Ibaraki JapanYuichi Kaji, University of Tsukuba Department of Ophthalmology, Institute of Clinical Medicine Ibaraki JapanNorishige Sakata, University Hospital of Tsukuba Department of Ophthalmology, Institute of Clinical Medicine 2-1-1 Amakubo Tsukuba Ibaraki 305-8576 JapanYuta Motoyama, Tsukuba Gakuen Hospital Department of ... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=3796976 Tue, 27 Jul 2010 09:11:58 +0100 3796976 http://www.medworm.com/index.php?rid=3741809&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd54x42816qn05471%2F We report a case of a giant iris cyst treated with neodymium-doped yttrium aluminum garnet laser cystotomy. A 33-year-old woman presented with nanophthalmos and ocular hypertension secondary to a giant iris cyst after congenital cataract surgery in the left eye. Examination with a rotating Scheimpflug camera and anterior-segment optical coherence tomography revealed a large iris cyst surrounding the pupillary region. She underwent laser iridocystotomy and irrigation of the anterior chamber. No recurrence of the iris cyst has been noted after 18 months and the IOP is normal. The cyst was treated successfully by laser cystotomy without other ocular tissue damage. Examination with a rotating Scheimpflug camera and anterior-segment optical coherence tomography proved to be simple an... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=3741809 Fri, 09 Jul 2010 06:18:21 +0100 3741809 http://www.medworm.com/index.php?rid=3722914&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv5u6742l414l2745%2F Editorial: Laser flare (cell) photometry: 20 years already Content Type Journal ArticleDOI 10.1007/s10792-010-9384-xAuthors Carl P. Herbort, Centre for Ophthalmic Specialized Care (COS), Clinique Montchoisi Inflammatory and Retinal Eye Diseases Lausanne SwitzerlandIlknur Tugal-Tutkun, Istanbul University Department of Ophthalmology, Istanbul Faculty of Medicine Istanbul Turkey Journal International OphthalmologyOnline ISSN 1573-2630Print ISSN 0165-5701 (Source: International Ophthalmology) International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=3722914 Thu, 01 Jul 2010 07:43:41 +0100 3722914 http://www.medworm.com/index.php?rid=3708706&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff84w823353113w78%2F Content Type Journal ArticleDOI 10.1007/s10792-010-9383-yAuthors Carl P. Herbort, Centre for Ophthalmic Specialized Care (COS), Clinique Montchoisi Inflammatory and Retinal Eye Diseases Lausanne SwitzerlandMoncef Khairallah, Fattouma Bourguiba University Hospital Department of Ophthalmology Monastir Tunisia Journal International OphthalmologyOnline ISSN 1573-2630Print ISSN 0165-5701 (Source: International Ophthalmology) International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=3708706 Fri, 25 Jun 2010 17:08:40 +0100 3708706 http://www.medworm.com/index.php?rid=3669097&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F136550316670jn55%2F Abstract  The efficacy and safety of a newly designed Ex-PRESS X-200 drainage device for the surgical treatment of glaucoma was evaluated. A clinical, prospective, monocentric, non-randomised, unmasked study on patients with medically uncontrolled glaucoma was performed. A superficial scleral flap was created. A posterior deep sclerectomy (DS) was dissected without opening the Schlemm’s canal and an Ex-PRESS X-200 device was inserted under the scleral flap into the anterior chamber to drain aqueous humour into the intrascleral space. Biomicroscopy, best-corrected visual acuity (BCVA), applanation intra-ocular pressure (IOP) measurements, and fundus examination were performed before surgery, on the first day, the first week, and 1, 2, 3, 6, 12 and 18 months after surg... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=3669097 Wed, 16 Jun 2010 07:17:28 +0100 3669097 http://www.medworm.com/index.php?rid=3642874&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F4k1411m77m5685r2%2F Abstract  The purpose of this article to report a case of ligneous conjunctivitis in an anophthalmic socket, in respect of a 20-year-old woman. The subject woman had a history of left enucleation surgery presented with bilateral palpebral ligneous conjunctivitis and ligneous gingivitis. The hematologic study revealed a severe plasma plasminogen deficiency. The eyelid lesions were successfully treated with surgical excision, topical heparin and corticosteroid eyedrops. However, the ligneous lesions recurred bilaterally after she was fitted with a prosthetic eye and were refractory to intensive topical treatment with heparin and cyclosporin A eye drops. This case shows that the use of a prosthetic eye may induce ligneous conjunctivitis in an anophthalmic socket and normal eye... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=3642874 Fri, 04 Jun 2010 06:48:58 +0100 3642874 http://www.medworm.com/index.php?rid=3642873&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv1744884q38l7282%2F Abstract  A 50-year-old man with multiple sclerosis developed unilateral acute retinal necrosis following a long-term systemic corticosteroid administration for treatment of an attack of paraparesis. The patient was treated with systemic acyclovir, aspirin, oral steroids and topical cyclopentolate and prednisolone acetate for almost 3 months. Pars plana vitrectomy and 360° endolaser photocoagulation posterior to necrotic retinal areas were performed a week after the initial diagnosis. Varicella zoster DNA was confirmed by PCR analysis in the vitreous sample. Two months later, pars plana vitrectomy with silicone oil injection was performed successfully to treat complicated retinal detachment. Careful peripheral fundus examination is essential when acute unexplained vis... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=3642873 Fri, 04 Jun 2010 06:48:58 +0100 3642873 http://www.medworm.com/index.php?rid=3642875&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft3631136j37151m1%2F Abstract  To report two cases of full-thickness macular hole (FTMH) formation associated with pigment epithelial detachment (PED). Two patients presenting with visual loss and metamorphopsia were evaluated with fundal fluorescein angiography (FFA) and optical coherence tomography (OCT). Case 1: Fundus examination and FFA revealed a small subfoveal PED. Subsequent serial OCT elucidated the progressive formation of a FTMH. Case 2: Fundus examination and FFA revealed a small PED and changes suggestive of central serous retinopathy (CSR). Subsequent OCT illustrated a FTMH with an underlying small PED at the base of the hole. It is possible that, in at least some cases of macular hole formation, there may be a causative link with PED. To my knowledge, this is the first report of ... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=3642875 Wed, 02 Jun 2010 14:08:54 +0100 3642875 http://www.medworm.com/index.php?rid=3611351&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj36q10505n26t61j%2F This study showed little evidence of any systematic difference between dilated and undilated flare measurements. The measurement of flare was not affected by the dilation of the pupil and measurements could be taken before or after papillary dilation for the purpose of patient follow-up data and clinical studies. Content Type Journal ArticleCategory Original PaperDOI 10.1007/s10792-010-9373-0Authors Felicia Ikeji, Research & Development Moorfields Eye Hospital Foundation Trust 162 City Road Old Street London EC1V 2PD UKCarlos Pavesio, Research & Development Moorfields Eye Hospital Foundation Trust 162 City Road Old Street London EC1V 2PD UKCatey Bunce, Research & Development Moorfields Eye Hospital Foundation Trust 162 City Road Old Street London EC1V 2PD UKEdward White, Research ... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=3611351 Wed, 26 May 2010 14:48:36 +0100 3611351 http://www.medworm.com/index.php?rid=3601532&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn14r05vw74636085%2F We present a case of a 16-year-old girl with fat embolism syndrome and involvement of the retina after a tibial fracture without any cardiac defect. Content Type Journal ArticleCategory Photo EssayDOI 10.1007/s10792-010-9378-8Authors Martin M. Nentwich, Ludwig-Maximilian University Department of Ophthalmology Mathildenstr. 8 80336 Munich GermanyMatthias Remy, Ludwig-Maximilian University Department of Ophthalmology Mathildenstr. 8 80336 Munich GermanyUlrich C. Schaller, Ludwig-Maximilian University Department of Ophthalmology Mathildenstr. 8 80336 Munich Germany Journal International OphthalmologyOnline ISSN 1573-2630Print ISSN 0165-5701 (Source: International Ophthalmology) International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=3601532 Mon, 24 May 2010 16:26:13 +0100 3601532 http://www.medworm.com/index.php?rid=3601534&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm673381572265248%2F Abstract  The aim of this study was to compare the intra-ocular pressure (IOP) obtained by ocular response analyzer (ORA), dynamic contour tonometer (DCT) and Goldmann applanation tonometer (GAT). In 102 patients (47 with primary open-angle glaucoma and 55 healthy controls) IOP was measured with GAT, ORA and DCT in one eye. The agreement between GAT, DCT and ORA values was assessed using Bland–Altman plots. The discrepancy between the methods was related to central corneal thickness (CCT), corneal hysteresis (CH) and corneal resistance factor (CRF) using linear regression models. Significant differences were observed amongst DCT, corneal compensated ORA (ORAcc) and GAT (P < 0.01). Only the ORAcc and DCT were comparable. ORAcc and DCT significantly over-estimat... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=3601534 Mon, 24 May 2010 16:26:10 +0100 3601534 http://www.medworm.com/index.php?rid=3601533&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw1671232n17408r8%2F This study found no statistically significant association between two common GSTP1 SNPs and MT2; however, a trend towards a greater frequency of the GG genotype of the Ile105Val SNP in cases is of great interest. The biological plausibility of disturbed macular pigment uptake in MT2 makes GSTP1 an excellent candidate gene. Further investigation is warranted in future studies of MT2. Content Type Journal ArticleCategory Original PaperDOI 10.1007/s10792-010-9374-zAuthors Joshua A. Szental, The Alfred Hospital Commercial Road, Prahran Melbourne VIC 3181 AustraliaPaul N. Baird, University of Melbourne Macular Research Unit, Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital Level 1, 32 Gisborne Street, East Melbourne Melbourne VIC 3002 AustraliaAndrea J. Richardso... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=3601533 Mon, 24 May 2010 16:26:10 +0100 3601533 http://www.medworm.com/index.php?rid=3601535&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F7x62863704500502%2F Abstract  To identify clinical features and prognostic factors in patients with Fuchs’ uveitis (FU). All patients diagnosed with FU at King Khaled Eye Specialist Hospital between 1983 and 2005 were reviewed. Data collected included age, gender, initial and final visual acuities, clinical findings at presentation and during follow-up visits, interval between onset of symptoms and presentation to our institute, ocular complications, details of surgical procedures, and duration of follow-up. One hundred and sixty-six patients (174 eyes) were identified. There were 92 (55.4%) males and 74 (44.6%) females with a mean age of 35.2 ± 10.5 years (range 10–70 years). The mean follow-up period was 57.3 ± 96.7 months (range 1–146 months). ... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=3601535 Sat, 22 May 2010 16:48:51 +0100 3601535 http://www.medworm.com/index.php?rid=3583644&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F9401x3kp95g51vt3%2F Abstract  To determine the efficacy of infliximab treatment in refractory posterior uveitis in Behçet’s disease after withdrawal of infusions. Four patients with posterior uveitis secondary to Behçet’s disease were treated with infliximab until complete remission and were followed after withdrawal of infusions. Intra-ocular inflammation was assessed using the binocular indirect ophthalmoscopy score, best-corrected visual acuity (BCVA) and foveal thickness measured by optic coherence tomography (OCT). All the patients included in the study were treated with infliximab for a minimum of 12 months and were in complete remission. None of the patients were taking steroids or immunosuppressants. Main follow-up after withdrawal of infusions was 7.5 months. Two out o... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=3583644 Wed, 19 May 2010 17:58:22 +0100 3583644 http://www.medworm.com/index.php?rid=3571799&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F44l365q77m255177%2F Abstract  To investigate the efficacy of anti-tuberculous therapy and systemic corticosteroids in patients suffering from active presumed tuberculous choroiditis by the assessment of central retinal sensitivity and fixation characteristics. Six patients (six eyes) with active presumed tuberculous choroiditis were treated with anti-tuberculous therapy and systemic corticosteroids. Mean central retinal sensitivities and fixation stability and location were investigated with MP-1 microperimetry before and after treatment. After a mean follow-up of 11.33 ± 7.53 months (range 6–24 months), all eyes showed resolution of inflammation, with no recurrences, associated with a significant improvement in visual acuity (P = 0.003). At the baseline, mean c... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=3571799 Sat, 15 May 2010 08:11:25 +0100 3571799 http://www.medworm.com/index.php?rid=3517490&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F6381671517545748%2F Abstract  Despite multiple advances in the management of retinoblastoma, enucleation remains an essential therapeutic modality. We studied patients who underwent enucleation at the King Hussein Cancer Center in Jordan. We retrospectively reviewed medical records of children with retinoblastoma who were treated at our center from June 2002 to February 2008. Twenty-eight eyes from 27 patients were enucleated. Median age at diagnosis was 1.1 years (range, 0.3–6.3 years). Twenty-six eyes (93%) had advanced disease (RE groups IV and V). Seventeen patients (61%) had unilateral retinoblastoma, and 11 (39%) had bilateral retinoblastoma. The median time from diagnosis to enucleation was 0.45 months (range, 0–45 months; mean, 4.4 months) and was longer for... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=3517490 Wed, 28 Apr 2010 08:04:52 +0100 3517490 http://www.medworm.com/index.php?rid=3509803&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F9p416340681h714v%2F Abstract  To describe the clinical manifestations and response to therapy of adult patients with tubulointerstitial nephritis and uveitis (TINU) syndrome and to provide suggested work-up and treatment. We retrospectively examined medical records of all adult patients suffering from TINU at Soroka University Medical Center (SUMC) over the past 15 years. Characteristics of ocular and nephrologic manifestations were investigated with particular attention given to age, presenting signs and symptoms, treatment and course of disease. Five adult patients (median age 44 years) were diagnosed with TINU syndrome and followed from 1991–2006 at SUMC. As renal involvement was present at initial evaluation in all patients, they were all treated with steroids. They all suffered ... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=3509803 Sat, 24 Apr 2010 08:06:56 +0100 3509803 http://www.medworm.com/index.php?rid=3502316&cid=s_33388_30_f&fid=33388&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F7l7632j7l02h3825%2F Abstract  Descemet’s membrane detachment (DMD) is a rare but potentially serious complication of intraocular surgery, most commonly cataract extraction. Many predisposing factors of DMD have been postulated; however, none have proved to be significant. Most DMDs are surgically induced; however, the occurrence of this entity bilaterally, during or after otherwise uneventful cataract extraction surgery, might be related to an inherent abnormal adhesion between the stroma and Descemet’s membrane or pre-existing endothelial abnormalities. Early recognition and proper management are important to preserve the vision and avoid permanent corneal damage. Although a small, localized detachment at the wound area tends to heal by spontaneous re-attachment, a larger or more progress... International Ophthalmology journals http://www.medworm.com/rss/comments.php?id=3502316 Thu, 22 Apr 2010 09:24:13 +0100 3502316