MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'JOP' source. Wed, 08 Feb 2012 16:28:20 +0100 http://www.medworm.com/index.php?rid=5580438&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22233940%26dopt%3DAbstract Authors: Osada S, Imai H, Sasaki Y, Tanaka Y, Nonaka K, Yoshida K Abstract Pancreatic fistula after pancreaticoduodenectomy represents a critical trigger of potentially life-threatening complications and is also associated with markedly prolonged hospitalization. Many arguments have been proposed for the method to anastomosis the pancreatic stump with the gastrointestinal tract, such as invagination vs. duct-to-mucosa, Billroth I (Imanaga) vs. Billroth II (Whipple and/or Child) or pancreaticogastrostomy vs. pancreaticojejunostomy. Although the best method for dealing with the pancreatic stump after pancreaticoduodenectomy remains in question, recent reports described the invagination method to decrease the rate of pancreatic fistula significantly compared to the duct-to-mucosa anas... JOP journals http://www.medworm.com/rss/comments.php?id=5580438 Sun, 01 Jan 2012 05:00:00 +0100 5580438 http://www.medworm.com/index.php?rid=5580437&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22233941%26dopt%3DAbstract Conclusion Hepaticogastrostomy and choledochoduodenostomy are feasible when performed by endoscopists with expertise in biliopancreatic endoscopy and advanced echo-endoscopy and should be performed currently under rigorous protocol in educational institutions. PMID: 22233941 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5580437 Sun, 01 Jan 2012 05:00:00 +0100 5580437 http://www.medworm.com/index.php?rid=5580436&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22233942%26dopt%3DAbstract Conclusion While the patients with duodenal perforation invariably require surgical intervention, most of the patients with perivaterian injuries can be successfully managed conservatively. The most important factors for recent better outcome were early detection and prompt treatment. Delay in diagnosis and intervention, salvage surgery after failed conservative management, multiple operations, and older age group contributed significantly to the poor outcome. PMID: 22233942 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5580436 Sun, 01 Jan 2012 05:00:00 +0100 5580436 http://www.medworm.com/index.php?rid=5580435&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22233943%26dopt%3DAbstract Conclusion It is important for physicians to have a high index of suspicion for diagnosing pancreatic plasmacytomas in the appropriate clinical setting (i.e., a previously diagnosed multiple myeloma, extramedullary plasmacytoma or any other plasma cell neoplasm). EUS-FNA is now an indispensable imaging modality to achieve the diagnosis of pancreatic extramedullary plasmacytomas with an inherently lower rate of complications, and should be the first choice for tissue evaluation. PMID: 22233943 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5580435 Sun, 01 Jan 2012 05:00:00 +0100 5580435 http://www.medworm.com/index.php?rid=5580434&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22233944%26dopt%3DAbstract Conclusions The suggested simple pancreaticojejunostomy method is easy and shows no evidence of significant pancreatic fistula. However, the potential risk of dysfunction in the remnant pancreas limits its possible clinical applications. The meticulous duct-to-mucosa pancreaticojejunostomy is highly preferred to manage the remnant pancreas following pancreaticoduodenectomy. PMID: 22233944 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5580434 Sun, 01 Jan 2012 05:00:00 +0100 5580434 http://www.medworm.com/index.php?rid=5580433&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22233945%26dopt%3DAbstract Conclusion Both the ARFI-VTQ and eSie touch elasticity imaging techniques may be successfully adopted in order to diagnose acute pancreatitis, to assess extent of inflammation (whether focal or diffuse), to assess peripancreatic edema, to identify presence of necrotic areas and early pseudocyst formation, to early diagnose acute recurrent attacks and to monitor patient's response to treatment. PMID: 22233945 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5580433 Sun, 01 Jan 2012 05:00:00 +0100 5580433 http://www.medworm.com/index.php?rid=5580432&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22233946%26dopt%3DAbstract Conclusions Most pancreatic tumor cells were more than 700 times more sensitive to NDV-LS killing than normal cells. Such avirulent, lentogenic NDV strains may have therapeutic potential in the treatment of pancreatic cancers. PMID: 22233946 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5580432 Sun, 01 Jan 2012 05:00:00 +0100 5580432 http://www.medworm.com/index.php?rid=5580431&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22233947%26dopt%3DAbstract Conclusions Migration of a balloon into the duodenum can result in external manipulation of the ampulla of Vater thereby disturbing the flow of pancreatic secretions leading to acute pancreatitis. Recognition of this complication is important and should be included as potential etiology of acute pancreatitis in patients receiving percutaneous endoscopic gastrostomy feedings. Periodic examination and documentation of the distance of the balloon from the skin should be performed to document the position of the tubes or any inadvertent migration of the tubes. The use of Foley catheters as permanent replacement tubes should be considered medically inappropriate. PMID: 22233947 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5580431 Sun, 01 Jan 2012 05:00:00 +0100 5580431 http://www.medworm.com/index.php?rid=5580430&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22233948%26dopt%3DAbstract Conclusions Pancreatic adenocarcinoma can rarely have the same presentation as colon cancer, and should therefore be considered in the differential diagnosis of large bowel obstruction. PMID: 22233948 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5580430 Sun, 01 Jan 2012 05:00:00 +0100 5580430 http://www.medworm.com/index.php?rid=5580429&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22233949%26dopt%3DAbstract Conclusions We have experienced a case of IPMN penetrating to the stomach and the common bile duct that has taken a slow course. It represents the importance of distinguishing mechanical penetration from invasive penetration as well as mechanical splenic vein obstruction from splenic vein invasion. PMID: 22233949 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5580429 Sun, 01 Jan 2012 05:00:00 +0100 5580429 http://www.medworm.com/index.php?rid=5580428&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22233950%26dopt%3DAbstract Conclusions This case highlights the difficulty to obtain a preoperative diagnosis of this pathological entity and the need of increased awareness about mature cystic teratoma when examining a pancreatic cystic lesion. PMID: 22233950 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5580428 Sun, 01 Jan 2012 05:00:00 +0100 5580428 http://www.medworm.com/index.php?rid=5580427&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22233951%26dopt%3DAbstract Conclusion It is important to diagnose hyperlipidemia by checking serum lipid profile for all pediatric patients presenting with hyperglycemic crisis to prevent morbidities. PMID: 22233951 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5580427 Sun, 01 Jan 2012 05:00:00 +0100 5580427 http://www.medworm.com/index.php?rid=5580426&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22233952%26dopt%3DAbstract Conclusion Pancreaticogastrostomy can be a treatment option for pancreatic transection. Rapid and simple damage control surgery with functional preservation of the organ will be beneficial for trauma patients. PMID: 22233952 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5580426 Sun, 01 Jan 2012 05:00:00 +0100 5580426 http://www.medworm.com/index.php?rid=5580425&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22233953%26dopt%3DAbstract Conclusion Thrombocytopenic purpura may be precipitate by acute pancreatitis due to multiple mechanisms. A high clinical suspicion is required to make an early diagnosis and allow early initiation of plasma exchange therapy, resulting in a good prognosis. PMID: 22233953 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5580425 Sun, 01 Jan 2012 05:00:00 +0100 5580425 http://www.medworm.com/index.php?rid=5580424&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22233954%26dopt%3DAbstract Conclusion True pancreatic cyst may show septate architecture and thus for imaging characterization this feature should be considered in the differential diagnosis of cystic pancreatic masses. PMID: 22233954 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5580424 Sun, 01 Jan 2012 05:00:00 +0100 5580424 http://www.medworm.com/index.php?rid=5580423&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22233955%26dopt%3DAbstract Conclusion Initially inoperable acinar cell carcinoma was treated by monotherapy using S-1, resulting in curative operation and two years disease free survival post operation. S-1 might be more effective on acinar cell carcinoma, rather than gemcitabine. PMID: 22233955 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5580423 Sun, 01 Jan 2012 05:00:00 +0100 5580423 http://www.medworm.com/index.php?rid=5580422&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22233956%26dopt%3DAbstract Conclusion Radiological drainage of peripancreatic fluid collections is generally regarded as having lower rates of complications compared to surgical necrosectomy. However, in this case it leads to a life threatening per rectal bleed requiring emergency splenic artery embolisation. PMID: 22233956 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5580422 Sun, 01 Jan 2012 05:00:00 +0100 5580422 http://www.medworm.com/index.php?rid=5580421&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22233957%26dopt%3DAbstract Conclusions Castleman's disease mimetizing pancreatic tumor is uncommon and it also curses with a difficult preoperative diagnosis. Surgery seems to be the best therapeutic alternative for this disease. PMID: 22233957 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5580421 Sun, 01 Jan 2012 05:00:00 +0100 5580421 http://www.medworm.com/index.php?rid=5580420&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22233958%26dopt%3DAbstract Conclusion The authors consider this to be the first report of successful EUS and EUS-FNA performed through the neoduodenum fashioned during pancreas-preserving total duodenectomy. PMID: 22233958 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5580420 Sun, 01 Jan 2012 05:00:00 +0100 5580420 http://www.medworm.com/index.php?rid=5580419&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22233959%26dopt%3DAbstract Conclusions To our knowledge, this is the first time laser lithotripsy has been employed to relieve basket impaction during attempted mechanical lithotripsy of a pancreatic duct stone. This method may be considered as a rescue technique by endoscopists encountering basket impaction in the future. PMID: 22233959 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5580419 Sun, 01 Jan 2012 05:00:00 +0100 5580419 http://www.medworm.com/index.php?rid=5580418&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22233960%26dopt%3DAbstract Conclusion Wernicke encephalopathy secondary to thiamine deficiency should be considered as a possible cause of acute mental status changes in patients with acute pancreatitis and malnutrition. Prophylactic doses of thiamine could be considered in susceptible patients. PMID: 22233960 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5580418 Sun, 01 Jan 2012 05:00:00 +0100 5580418 http://www.medworm.com/index.php?rid=5580417&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22233961%26dopt%3DAbstract Conclusion The CT, MRI and MRCP findings in dorsal pancreatic agenesis and the relationship between the length of ventral duct with the type of dorsal pancreatic agenesis will provide a new insight into this particular anomaly. PMID: 22233961 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5580417 Sun, 01 Jan 2012 05:00:00 +0100 5580417 http://www.medworm.com/index.php?rid=5580416&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22233962%26dopt%3DAbstract Authors: Mrzljak A, Sobočan N, Novačić K, Skegro D, Košuta I, Katičić M PMID: 22233962 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5580416 Sun, 01 Jan 2012 05:00:00 +0100 5580416 http://www.medworm.com/index.php?rid=5580415&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22233963%26dopt%3DAbstract Authors: Pezzilli R PMID: 22233963 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5580415 Sun, 01 Jan 2012 05:00:00 +0100 5580415 http://www.medworm.com/index.php?rid=5428417&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22072244%26dopt%3DAbstract Authors: Nguyen VX, Nguyen CC, Nguyen BD Abstract Since the introduction of integrated positron emission tomography-computed tomography (PET/CT), it has a great impact on the field of oncology. Comparing to other conventional scanners, only PET/CT is capable of providing important information on accurate detecting, staging/restaging, and post-therapeutic monitoring of many cancers. Many studies have demonstrated that PET/CT changes the management in approximately 30% of all cancer patients. Because 2-((18)F)-fluoro-2-deoxy-D-glucose (FDG) is a nonspecific tracer, understanding the PET/CT limitations and pitfalls for various pancreatic conditions can lead to more accurate interpretation of PET/CT images, which ultimately would impact patient care. As a result, it is important for ra... JOP journals http://www.medworm.com/rss/comments.php?id=5428417 Sun, 20 Nov 2011 13:48:02 +0100 5428417 http://www.medworm.com/index.php?rid=5428416&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22072245%26dopt%3DAbstract CONCLUSIONS: The distribution of pancreatic hormones is altered to varying extents in the ZDF rat and during the normal aging process. PMID: 22072245 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5428416 Sun, 20 Nov 2011 13:48:02 +0100 5428416 http://www.medworm.com/index.php?rid=5428415&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22072246%26dopt%3DAbstract CONCLUSION: Nasojejunal nutrition, commenced in hospital and continued at home, is safe, efficacious and well tolerated in patients with severe chronic pancreatitis and is effective in helping to relieve pain and diminish analgesic requirements. PMID: 22072246 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5428415 Sun, 20 Nov 2011 13:48:02 +0100 5428415 http://www.medworm.com/index.php?rid=5428414&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22072247%26dopt%3DAbstract CONCLUSIONS: Routine prescription drugs, as an aetiological factor, accounted for 3.4% of cases of acute pancreatitis. The disease appeared to be more common in middle-aged women. It is likely that the overall incidence of this entity is under-reported owing to the stringent criteria needed to conclusively determine a causal relationship. PMID: 22072247 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5428414 Sun, 20 Nov 2011 13:48:02 +0100 5428414 http://www.medworm.com/index.php?rid=5428413&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22072248%26dopt%3DAbstract CONCLUSIONS: Obese patients have an increased risk for pancreatic fistula after pancreaticoduodenectomy. PMID: 22072248 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5428413 Sun, 20 Nov 2011 13:48:02 +0100 5428413 http://www.medworm.com/index.php?rid=5428412&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22072249%26dopt%3DAbstract CONCLUSION: Malignancy at the ampulla of Vater causing recurrent episodes of pancreatitis represents a realistic risk and attempts to diagnose the underlying cause should always take into account the possibility of cancer. PMID: 22072249 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5428412 Sun, 20 Nov 2011 13:48:02 +0100 5428412 http://www.medworm.com/index.php?rid=5428411&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22072250%26dopt%3DAbstract CONCLUSION: Several studies have been attempted to clarify the points of differentiation between carcinoma and pancreatitis in the groove area. This discrimination has been proved to be difficult; frequently the definitive diagnosis is only obtained after surgical intervention. This condition should be considered when making the differential diagnosis in pancreatic groove pathology and duodenal stenosis. PMID: 22072250 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5428411 Sun, 20 Nov 2011 13:48:02 +0100 5428411 http://www.medworm.com/index.php?rid=5428410&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22072251%26dopt%3DAbstract CONCLUSION: For diagnosis of intrapancreatic accessory spleen, radiographic imaging is useful, but lacks specificity without tissue diagnosis. Diagnosis can be safely and reliably established with EUS-FNA, leading to a benign prognosis and avoidance of unnecessary surgical intervention. PMID: 22072251 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5428410 Sun, 20 Nov 2011 13:48:02 +0100 5428410 http://www.medworm.com/index.php?rid=5428409&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22072252%26dopt%3DAbstract CONCLUSION: This case highlights importance of preoperative histological diagnosis of periampullary tumors to avoid morbid surgical procedure in the form pancreaticoduodenectomy. Ectopic pancreas should include differential diagnosis of periampullary tumors. PMID: 22072252 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5428409 Sun, 20 Nov 2011 13:48:02 +0100 5428409 http://www.medworm.com/index.php?rid=5428408&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22072253%26dopt%3DAbstract CONCLUSION: The indication of these procedures must be made under a multidisciplinary view while sharing information with the patient or legal guardian. EUS-guided biliary drainage is feasible when performed by professionals with expertise in biliopancreatic endoscopy and advanced echo-endoscopy and should be performed currently under rigorous protocol in educational institutions. PMID: 22072253 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5428408 Sun, 20 Nov 2011 13:48:02 +0100 5428408 http://www.medworm.com/index.php?rid=5428407&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22072254%26dopt%3DAbstract Authors: Patel NC, Palmer WC, Krishna M, Lewis MD, Wallace MB PMID: 22072254 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5428407 Sun, 20 Nov 2011 13:48:02 +0100 5428407 http://www.medworm.com/index.php?rid=5428406&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22072255%26dopt%3DAbstract Authors: Pezzilli R PMID: 22072255 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5428406 Sun, 20 Nov 2011 13:48:02 +0100 5428406 http://www.medworm.com/index.php?rid=5383630&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21978312%26dopt%3DAbstract Authors: Prochaska JO PMID: 21978312 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5383630 Tue, 01 Nov 2011 04:00:00 +0100 5383630 http://www.medworm.com/index.php?rid=5221793&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21904067%26dopt%3DAbstract Authors: Uomo I PMID: 21904067 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5221793 Fri, 16 Sep 2011 03:00:02 +0100 5221793 http://www.medworm.com/index.php?rid=5221792&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21904068%26dopt%3DAbstract CONCLUSIONS: Adjuvant 5-FU-based chemoradiation following radical pancreatectomy can be delivered safely and results in comparatively good overall survival. The results of this analysis underscore the importance of resection status, number of involved lymph nodes and patient age as prognostic characteristics. These factors may be considered stratification variables for future post-pancreatectomy adjuvant therapy trials. PMID: 21904068 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5221792 Fri, 16 Sep 2011 03:00:02 +0100 5221792 http://www.medworm.com/index.php?rid=5221791&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21904069%26dopt%3DAbstract CONCLUSION: Experimental, intra- and postoperative instrumental investigations did not show the short gastric arteries to be engaged in the blood supply to the spleen after a spleen-preserving distal pancreatectomy with resection of the splenic vessels. In all cases, the left gastroepiploic artery was the main collateral vessel. PMID: 21904069 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5221791 Fri, 16 Sep 2011 03:00:02 +0100 5221791 http://www.medworm.com/index.php?rid=5221790&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21904070%26dopt%3DAbstract CONCLUSIONS: Heterotopic pancreatic tissue is a rare pathological finding in the gallbladder. It requires consideration and sensitization in the differential diagnosis of acalculous gallbladder disease, which can explain hyperamylasuria in cases of unknown origin. PMID: 21904070 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5221790 Fri, 16 Sep 2011 03:00:02 +0100 5221790 http://www.medworm.com/index.php?rid=5221789&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21904071%26dopt%3DAbstract CONCLUSION: Single operator cholangioscopy provides a safe means of diagnosing and treating patients with biliary cast syndrome. PMID: 21904071 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5221789 Fri, 16 Sep 2011 03:00:02 +0100 5221789 http://www.medworm.com/index.php?rid=5221788&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21904072%26dopt%3DAbstract CONCLUSION: The above results suggested that this pancreatic ductal adenocarcinoma with lipomatous pseudohypertrophy might be an example of very early stage tumor progression. PMID: 21904072 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5221788 Fri, 16 Sep 2011 03:00:02 +0100 5221788 http://www.medworm.com/index.php?rid=5221787&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21904073%26dopt%3DAbstract CONCLUSION: Timely intervention, either by embolization or by surgery, can control this potentially life-threatening bleeding. Choice of treatment, surgery or embolization, depends on technological availability and expertise of the practitioner. PMID: 21904073 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5221787 Fri, 16 Sep 2011 03:00:02 +0100 5221787 http://www.medworm.com/index.php?rid=5221786&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21904074%26dopt%3DAbstract CONCLUSION: Cystic lymphangioma should be considered in the differential diagnosis of cystic pancreatic lesions in which the morphology is difficult to characterize. EUS-FNA has the potential of rendering a positive diagnosis of this benign entity. PMID: 21904074 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5221786 Fri, 16 Sep 2011 03:00:02 +0100 5221786 http://www.medworm.com/index.php?rid=5221785&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21904075%26dopt%3DAbstract CONCLUSION: In HIV-infected patients, acute pancreatitis may present on imaging studies as autoimmune pancreatitis. In patients with uncontrolled HIV infection and imaging studies suggestive of autoimmune pancreatitis, direct HIV-related inflammation should be considered after exclusion of all other causes of pancreatitis. PMID: 21904075 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5221785 Fri, 16 Sep 2011 03:00:02 +0100 5221785 http://www.medworm.com/index.php?rid=5221784&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21904076%26dopt%3DAbstract CONCLUSIONS: Vitamin D deficiency due to exocrine pancreatic insufficiency should be kept in mind as one of the reasons for impaired gait and skeletal muscle weakness. PMID: 21904076 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5221784 Fri, 16 Sep 2011 03:00:02 +0100 5221784 http://www.medworm.com/index.php?rid=5221783&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21904077%26dopt%3DAbstract CONCLUSION: We report a rare presentation of chronic pancreatitis with a perinephric abscess and its non-surgical management. This case report indicates that any patient presenting with a perinephric abscess of unknown etiology not responding to conventional treatment modalities should be investigated for underlying pancreatitis. PMID: 21904077 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5221783 Fri, 16 Sep 2011 03:00:02 +0100 5221783 http://www.medworm.com/index.php?rid=5221782&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21904078%26dopt%3DAbstract CONCLUSION: A clinically significant pancreatic leak can occur as a rare complication of EUS-FNA that can be effectively managed by endoscopic retrograde pancreatography and placement of a transpapillary pancreatic duct stent. PMID: 21904078 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5221782 Fri, 16 Sep 2011 03:00:02 +0100 5221782 http://www.medworm.com/index.php?rid=5221781&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21904079%26dopt%3DAbstract Authors: Dumitrascu T, Popescu I PMID: 21904079 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5221781 Fri, 16 Sep 2011 03:00:02 +0100 5221781 http://www.medworm.com/index.php?rid=5221780&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21904080%26dopt%3DAbstract Authors: Kurosaki I, Minagawa M, Takano K, Takizawa K, Hatakeyama K PMID: 21904080 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5221780 Fri, 16 Sep 2011 03:00:02 +0100 5221780 http://www.medworm.com/index.php?rid=5221779&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21904081%26dopt%3DAbstract Authors: Pezzilli R, Imbrogno A, Fabbri D, Corinaldesi R PMID: 21904081 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5221779 Fri, 16 Sep 2011 03:00:02 +0100 5221779 http://www.medworm.com/index.php?rid=5115149&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21812121%26dopt%3DAbstract Authors: PMID: 21812121 [PubMed - indexed for MEDLINE] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5115149 Thu, 11 Aug 2011 15:15:03 +0100 5115149 http://www.medworm.com/index.php?rid=5020870&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21737886%26dopt%3DAbstract Authors: Saif MW Pancreatic cancer still is a significant, unresolved therapeutic challenge with nearly similar incidence and mortality rates. It is the most lethal type of digestive cancer with a 5-year survival rate of 5%. Adjuvant chemotherapy remains to be gemcitabine alone or combined with infusional 5-fluorouracil with radiation therapy. Nevertheless, only a few patients survive for at least 5 years after R0 resection and adjuvant therapy. Most patients need palliative treatment. Once pancreatic cancer becomes metastatic, it is uniformly fatal with an overall survival of typically 6 months from diagnosis. Chemotherapy is an important component of palliative care but must be administered as a part of a multidisciplinary approach, including palliation of pain, managing weight loss,... JOP journals http://www.medworm.com/rss/comments.php?id=5020870 Wed, 13 Jul 2011 16:30:03 +0100 5020870 http://www.medworm.com/index.php?rid=5020869&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21737887%26dopt%3DAbstract Screening and Detection of Pancreatic Cancer. Highlights from the "2011 ASCO Annual Meeting". Chicago, IL, USA; June 3-7, 2011. JOP. 2011;12(4):322-4 Authors: Gonda TA, Lucas A, Saif MW Screening and early detection of pancreatic cancer has the potential to substantially impact outcomes in this deadly disease. Over the last ten years several cohort studies have been conducted and report on the yield of screening in high risk populations. With better understanding of the cellular compartments and the genetic and epigenetic changes that occur, biomarkers have also emerged as promising means of early detection. In this paper we summarize the results of the latest screening cohort and highlight a novel proteomic approach that may be used in future biomarker studies. PMID: 21737... JOP journals http://www.medworm.com/rss/comments.php?id=5020869 Wed, 13 Jul 2011 16:30:03 +0100 5020869 http://www.medworm.com/index.php?rid=5020868&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21737888%26dopt%3DAbstract Biomarkers and Pharmacogenetics in Pancreatic Cancer. Highlights from the "2011 ASCO Annual Meeting". Chicago, IL, USA; June 3-7, 2011. JOP. 2011;12(4):325-9 Authors: Xu X, Strimpakos AS, Saif MW Appropriate identification and validation of biomarkers as well as pharmacogenetics are important in formulating patient-oriented, individualized chemotherapy or biological therapy in cancer patients. These markers can be especially valuable in pancreatic cancer, where high mortality and complex disease biology are frequently encountered. Recently, several advances have been made to further our knowledge in this specific area of pancreatic cancer. In the 2011 American Society of Clinical Oncology (ASCO) Annual Meeting, researchers have presented several interesting results in biomarker... JOP journals http://www.medworm.com/rss/comments.php?id=5020868 Wed, 13 Jul 2011 16:30:03 +0100 5020868 http://www.medworm.com/index.php?rid=5020867&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21737889%26dopt%3DAbstract Diabetes and Pancreatic Cancer. Highlights from the "2011 ASCO Annual Meeting". Chicago, IL, USA; June 3-7, 2011. JOP. 2011;12(4):330-3 Authors: Hsu C, Saif MW Pancreatic cancer is the fourth leading cause of cancer death in the United States. Risk factors for pancreatic cancer are smoking, family history, chronic pancreatitis, and diabetes. There is controversy with regards to the causal relationship between diabetes and pancreatic cancer because many patients with pancreatic cancer have new onset diabetes. Abstracts presented at the 2011 American Society of Clinical Oncology (ASCO) Annual Meeting highlighted and supported the positive association between pancreatic cancer and diabetes. Abstract #4102 reports a two-fold risk of pancreatic cancer in diabetic patients. Abstract ... JOP journals http://www.medworm.com/rss/comments.php?id=5020867 Wed, 13 Jul 2011 16:30:03 +0100 5020867 http://www.medworm.com/index.php?rid=5020866&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21737890%26dopt%3DAbstract Novel Agents for the Treatment of Pancreatic Adenocarcinoma. Highlights from the "2011 ASCO Annual Meeting". Chicago, IL, USA; June 3-7, 2011. JOP. 2011;12(4):334-8 Authors: Cheng H, Merika E, Syrigos KN, Saif MW There are urgent needs to develop novel and more effective regimens to improve outcomes of pancreatic cancer given its dismal prognosis and limited treatment options. Several phase I clinical trials involving novel agents were recently presented at the 2011 American Society of Clinical Oncology (ASCO) Annual Meeting. It appears that hedgehog inhibition with IPI-926 was well-tolerated and might be effective in treating pancreatic cancer when combined with gemcitabine. The survival benefits will be tested in the following randomized phase II trial. The new combination of... JOP journals http://www.medworm.com/rss/comments.php?id=5020866 Wed, 13 Jul 2011 16:30:03 +0100 5020866 http://www.medworm.com/index.php?rid=5020865&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21737891%26dopt%3DAbstract Updates on First-Line Treatment of Metastatic Pancreatic Adenocarcinoma. Highlights from the "2011 ASCO Annual Meeting". Chicago, IL, USA; June 3-7, 2011. JOP. 2011;12(4):339-42 Authors: Strimpakos AS, Syrigos KN, Saif MW Despite the extensive research, mounting knowledge in the cancer field and enormous investments, pancreatic cancer remains a rather incurable disease with aggressive natural course and high mortality rate. The very slow progress is a result of the complex pathogenesis of this disease, which prevents us from targeting the culprit and making a step forward. Therefore, the field is still unexplored and this is a real challenge and opportunity for new ideas and novel approaches. In this paper, we will present the most interesting studies in the first line pancreat... JOP journals http://www.medworm.com/rss/comments.php?id=5020865 Wed, 13 Jul 2011 16:30:03 +0100 5020865 http://www.medworm.com/index.php?rid=5020864&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21737892%26dopt%3DAbstract In conclusion, multiple adjuvant therapeutic regimens are associated with incremental improvements in the management of pancreatic cancer. The timing of initiation of adjuvant therapy appears to be important in outcomes. Research is ongoing into markers that can predict response to adjuvant therapy. PMID: 21737892 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5020864 Wed, 13 Jul 2011 16:30:03 +0100 5020864 http://www.medworm.com/index.php?rid=5020862&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21737893%26dopt%3DAbstract Locally Advanced Pancreatic Adenocarcinoma: Are We Making Progress?. Highlights from the "2011 ASCO Annual Meeting". Chicago, IL, USA; June 3-7, 2011. JOP. 2011;12(4):347-50 Authors: Li J, Ng J, Allendorf J, Saif MW Pancreatic cancer, as the 4th leading cause of cancer death in the U.S., remains a challenging disease for all oncologists. Less than 20% of all cases could be potentially cured by surgical resection, while the majority of cases are deemed either unresectable or metastatic upon diagnosis. In this year's American Society of Clinical Oncology (ASCO) Annual Meeting, several studies were presented with novel approaches towards treating locally advanced pancreatic cancer. The LAP-07 study, a large phase III study with two separate randomizations, updated their accrual st... JOP journals http://www.medworm.com/rss/comments.php?id=5020862 Wed, 13 Jul 2011 16:30:03 +0100 5020862 http://www.medworm.com/index.php?rid=5020861&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21737894%26dopt%3DAbstract Updates on Treatment of Gemcitabine-Refractory Pancreatic Adenocarcinoma. Highlights from the "2011 ASCO Annual Meeting". Chicago, IL, USA; June 3-7, 2011. JOP. 2011;12(4):351-4 Authors: Makrilia N, Syrigos KN, Saif MW Gemcitabine monotherapy and gemcitabine-based regimens are the current standard of care for locally advanced or metastatic pancreatic adenocarcinoma. However, there is still great controversy over the role of salvage chemotherapy after failure of gemcitabine. This review is an update on the 2011 American Society of Clinical Oncology (ASCO) Annual Meeting regarding the most important developments in the treatment of refractory pancreatic cancer, as they were reported in Abstracts #e14542 and #e14588. PMID: 21737894 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5020861 Wed, 13 Jul 2011 16:30:03 +0100 5020861 http://www.medworm.com/index.php?rid=5020860&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21737895%26dopt%3DAbstract Palliative Care of Pancreatic Cancer. Highlights from the "2011 ASCO Annual Meeting". Chicago, IL, USA; June 3-7, 2011. JOP. 2011;12(4):355-7 Authors: Saif MW Pancreatic cancer is one of the most fatal malignancies. Palliative care represents an important aspect of management in patients with pancreatic malignancy. Identifying and treating disease related symptoms are very important. As a physician taking care of these patients it is essential to know these symptoms and treatment modalities. Common problems include biliary obstruction, anticoagulation, and pain management. This review discusses the data presented at the 2011 American Society of Clinical Oncology (ASCO) Annual Meeting symptom management and supportive care strategies including Abstracts #e14665, #e14622, and #LB... JOP journals http://www.medworm.com/rss/comments.php?id=5020860 Wed, 13 Jul 2011 16:30:03 +0100 5020860 http://www.medworm.com/index.php?rid=5020859&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21737896%26dopt%3DAbstract Novel Agents in the Treatment of Unresectable Neuroendocrine Tumors. Highlights from the "2011 ASCO Annual Meeting". Chicago, IL, USA; June 3-7, 2011. JOP. 2011;12(4):358-61 Authors: Oberstein PE, Saif MW Pancreatic neuroendocrine tumors represent a small percentage of all pancreatic tumors (1.3%) but their incidence is rising. Prior to 2011, the only approved agent for unresectable disease was streptozicin (often used in combination with doxorubicin) but the efficacy of this drug is in question and there had not been any new drugs approved for this disease in more than 20 years. Recently there has been new excitement for the treatment of advanced neuroendocrine tumors including those of the pancreas (pNET) with FDA approval of 2 new agents in 2011. One of these agents was ever... JOP journals http://www.medworm.com/rss/comments.php?id=5020859 Wed, 13 Jul 2011 16:30:03 +0100 5020859 http://www.medworm.com/index.php?rid=5020858&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21737897%26dopt%3DAbstract Adjuvant Treatment for Ampullary Cancer. Highlights from the "2011 ASCO Annual Meeting". Chicago, IL, USA; June 3-7, 2011. JOP. 2011;12(4):362-3 Authors: Kim R, Chabot J, Saif MW Ampullary cancer is an uncommon tumor and tends to have a better prognosis than pancreatic cancer. However, one half of patients will die from recurrent disease suggesting the need for effective adjuvant therapy. Currently, there is lack of randomized trials to guide the use of adjuvant therapy in ampullary cancer. At the 2011 American Society of Clinical Oncology (ASCO) Annual Meeting, the largest trial (Abstract #4006) evaluating adjuvant treatment of ampullary cancer was presented. PMID: 21737897 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5020858 Wed, 13 Jul 2011 16:30:03 +0100 5020858 http://www.medworm.com/index.php?rid=5020857&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21737898%26dopt%3DAbstract Authors: Hildebrand P, Duderstadt S, Jungbluth T, Roblick UJ, Bruch HP, Czymek R Pain is the main symptom of chronic pancreatitis. However, in addition to an improvement in pain symptoms, an increase in the quality of life also influences therapeutic success. The present paper evaluates the influence of surgery on chronic pancreatitis, and the early and late postoperative quality of life. PMID: 21737898 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5020857 Wed, 13 Jul 2011 16:30:03 +0100 5020857 http://www.medworm.com/index.php?rid=5020856&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21737899%26dopt%3DAbstract Authors: Sutton VR, Hong MK, Thomas PR Post-ERCP pancreatitis is the most common complication of endoscopic retrograde cholangiopancreatography (ERCP). A simple method of predicting patients who are at risk of developing post-ERCP pancreatitis is needed to allow those at low risk to be discharged on the same day of their procedure. The aim of this study was to confirm that 4-hour post-ERCP serum amylase level is predictive of post-ERCP pancreatitis. PMID: 21737899 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5020856 Wed, 13 Jul 2011 16:30:03 +0100 5020856 http://www.medworm.com/index.php?rid=5020855&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21737900%26dopt%3DAbstract Authors: Buxbaum JL, Biggins SW, Bagatelos KC, Inadomi JM, Ostroff JW Endoscopically placed metal stents, which are patent for 4-9 months, have been the favored decompressive strategy for biliary obstruction due to inoperable pancreatic cancer in order to minimize interventions. However, in the past decade chemotherapeutic options have improved survival. This raises the question of whether metal stents will continue to be the optimal method of decompression. PMID: 21737900 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5020855 Wed, 13 Jul 2011 16:30:03 +0100 5020855 http://www.medworm.com/index.php?rid=5020854&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21737901%26dopt%3DAbstract Authors: Chalian H, Töre HG, Miller FH, Yaghmai V There is extensive overlap among the imaging characteristics of pseudocyst, mucinous cystic neoplasm (MCN) and side branch intraductal papillary mucinous neoplasm (IPMN) on CT images. PMID: 21737901 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5020854 Wed, 13 Jul 2011 16:30:03 +0100 5020854 http://www.medworm.com/index.php?rid=5020853&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21737902%26dopt%3DAbstract Authors: Liu LS, Shenoy M, Pasricha PJ Calcitonin gene-related peptide (CGRP), substance P and nerve growth factor play an important role in inflammatory pain in various somatic pain models but their role in chronic pancreatitis has not been well studied. PMID: 21737902 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5020853 Wed, 13 Jul 2011 16:30:03 +0100 5020853 http://www.medworm.com/index.php?rid=5020849&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21737903%26dopt%3DAbstract Authors: Pour PM, Saruc M The association between islet cells and neural elements, the so-called "neuro-insular complex", has been known for centuries. PMID: 21737903 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5020849 Wed, 13 Jul 2011 16:30:03 +0100 5020849 http://www.medworm.com/index.php?rid=5020846&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21737904%26dopt%3DAbstract We report a case of massive poisoning with meprobamate leading to acute pancreatitis. PMID: 21737904 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5020846 Wed, 13 Jul 2011 16:30:03 +0100 5020846 http://www.medworm.com/index.php?rid=5020842&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21737905%26dopt%3DAbstract We report a rare case of autoimmune neutropenia associated with autoimmune pancreatitis. PMID: 21737905 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5020842 Wed, 13 Jul 2011 16:30:03 +0100 5020842 http://www.medworm.com/index.php?rid=5020841&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21737906%26dopt%3DAbstract Authors: Ito Y, Irino T, Egawa T, Hayashi S, Nagashima A Pancreatic fistulas still occur despite refinements in both surgical technique and perioperative management after a pancreaticoduodenectomy. However, the occurrence of delayed pancreatic fistulas is very rare. PMID: 21737906 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5020841 Wed, 13 Jul 2011 16:30:03 +0100 5020841 http://www.medworm.com/index.php?rid=5020840&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21737907%26dopt%3DAbstract Authors: Gupta V, Gupta P, Jain A Brunner's gland adenoma is a rare benign duodenal neoplasm. It usually presents with luminal obstruction or gastrointestinal bleeding. In rare cases, it may mimic a pancreatic malignancy and may present with obstructive jaundice. PMID: 21737907 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5020840 Wed, 13 Jul 2011 16:30:03 +0100 5020840 http://www.medworm.com/index.php?rid=5020839&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21737908%26dopt%3DAbstract Authors: Gómez Mateo Mdel C, Muñoz Forner E, Sabater Ortí L, Ferrández Izquierdo A Foregut cystic malformations are common lesions in the mediastinum but are rarely found in subdiaphragmatic locations. Only a few cases have been described within the pancreas where they can easily be misdiagnosed as cystic neoplasms. PMID: 21737908 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5020839 Wed, 13 Jul 2011 16:30:03 +0100 5020839 http://www.medworm.com/index.php?rid=5020838&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21737909%26dopt%3DAbstract Authors: Saif MW Sandostatin® LAR® depot is a synthetic analogue of the naturally occurring hormone somatostatin and is indicated for certain patients with acromegaly and severe diarrhea and flushing episodes associated with metastatic carcinoid tumors and for the long-term treatment of the profuse watery diarrhea associated with VIP-secreting tumors in patients in whom initial treatment with immediate release Sandostatin® injection has been shown to be effective and tolerated. The most common toxicities include biliary disorders, gastrointestinal disorders, injection-site pain, hypoglycemia and hyperglycemia. Rheumatoid arthritis or similar toxicities have not been associated with Sandostatin® LAR® depot. PMID: 21737909 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5020838 Wed, 13 Jul 2011 16:30:03 +0100 5020838 http://www.medworm.com/index.php?rid=5020837&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21737910%26dopt%3DAbstract The "Hanging Maneuver" Technique during Pancreaticoduodenectomy: The Result of a Technical Evolution to Approach the Superior Mesenteric Artery. JOP. 2011;12(4):429-30 Authors: Marzano E, Piardi T, Pessaux P PMID: 21737910 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5020837 Wed, 13 Jul 2011 16:30:03 +0100 5020837 http://www.medworm.com/index.php?rid=5020836&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21737911%26dopt%3DAbstract Authors: Uomo G PMID: 21737911 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=5020836 Wed, 13 Jul 2011 16:30:03 +0100 5020836 http://www.medworm.com/index.php?rid=4924994&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21645137%26dopt%3DAbstract Conclusions and Clinical Relevance This study reinforces evidence that, apart from a local cutaneous inflammation, CU is associated with a systemic inflammatory response. Such acute-phase response is manifested by increased circulating IL-6, which varies along with CRP changes and may be related to the urticarial activity. PMID: 21645137 [PubMed - as supplied by publisher] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4924994 Sun, 05 Jun 2011 23:00:00 +0100 4924994 http://www.medworm.com/index.php?rid=4824901&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21546695%26dopt%3DAbstract Authors: Gray S, Pandha HS, Michael A, Middleton G, Morgan R The HOX genes are a family of homeodomain-containing transcription factors that determine cellular identity during development and which are subsequently re-expressed in many types of cancer. Some recent studies have shown that HOX genes may have key roles both in pancreatic development and in adult diseases of the pancreas, including cancer. In this review we consider recent advances in elucidating the role of HOX genes in these processes, how they may connect early developmental events to subsequent adult disease, and their potential both as diagnostic markers and therapeutic targets. PMID: 21546695 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4824901 Mon, 16 May 2011 10:45:03 +0100 4824901 http://www.medworm.com/index.php?rid=4824900&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21546696%26dopt%3DAbstract Authors: Kurosaki I, Minagawa M, Takano K, Takizawa K, Hatakeyama K Dissection of the superior mesenteric artery is the most important part of a pancreaticoduodenectomy for pancreatic cancer. Since 2005, we have used the left posterior approach for superior mesenteric vascular pedicle dissection, in which the superior mesenteric artery and the superior mesenteric vein are dissected first in a clockwise fashion. PMID: 21546696 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4824900 Mon, 16 May 2011 10:45:03 +0100 4824900 http://www.medworm.com/index.php?rid=4824899&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21546697%26dopt%3DAbstract Authors: Manzelli A, Petrou A, Lazzaro A, Brennan N, Soonawalla Z, Friend P Groove pancreatitis is a rare condition characterized by fibrotic inflammation affecting the groove anatomical area between the head of the pancreas, the duodenum and the common bile duct. PMID: 21546697 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4824899 Mon, 16 May 2011 10:45:03 +0100 4824899 http://www.medworm.com/index.php?rid=4824898&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21546698%26dopt%3DAbstract Authors: Choi SH, Hwang HK, Kang CM, Lee WJ Various techniques for reconstruction after superior mesenteric-splenic-portal vein confluence resection during pancreaticoduodenectomy have been introduced. A certain kind of vascular grafting may be necessary especially when long segmental resection of superior mesenteric-splenic-portal vein confluence is required. PMID: 21546698 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4824898 Mon, 16 May 2011 10:45:03 +0100 4824898 http://www.medworm.com/index.php?rid=4824897&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21546699%26dopt%3DAbstract Authors: Stock C, Keutgen XM, Pisapia D, Crawford C, Zarnegar R Heterotopic pancreatic adenocarcinoma is a rare finding at laparotomy. Herein we present the case of a patient with malignant transformation of a heterotopic pancreas located in the fourth portion of the duodenum. PMID: 21546699 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4824897 Mon, 16 May 2011 10:45:03 +0100 4824897 http://www.medworm.com/index.php?rid=4824896&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21546700%26dopt%3DAbstract Authors: Chahal P, Saad AJ, Jeyarajah RD Synchronous cystic neoplasms of pancreas are a highly rare occurrence. PMID: 21546700 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4824896 Mon, 16 May 2011 10:45:03 +0100 4824896 http://www.medworm.com/index.php?rid=4824895&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21546701%26dopt%3DAbstract Authors: Sheikh I, Kanwal A, Kyprianou A While the majority of acute pancreatitis is secondary to alcohol and gallstones in the developed world, infectious causes are recognized and recent evidence has linked influenza A to acute pancreatitis. PMID: 21546701 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4824895 Mon, 16 May 2011 10:45:03 +0100 4824895 http://www.medworm.com/index.php?rid=4824894&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21546702%26dopt%3DAbstract Authors: Venkatesh PG, Navaneethan U Azathioprine induced pancreatitis usually runs a benign self limited course with rapid disappearance of signs and symptoms upon with drawl of the drug. Azathioprine is used in treating relapses in patients with autoimmune pancreatitis and maintenance of remission in autoimmune hepatitis. Acute pancreatitis complicated by symptomatic pseudocysts requiring drainage is not usually associated with drug induced pancreatitis. The risk of azathioprine use in patients with underlying disease of pancreas including autoimmune pancreatitis is unclear. PMID: 21546702 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4824894 Mon, 16 May 2011 10:45:03 +0100 4824894 http://www.medworm.com/index.php?rid=4824893&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21546703%26dopt%3DAbstract Authors: Maurea S, Corvino A, Imbriaco M, Avitabile G, Mainenti P, Camera L, Galizia G, Salvatore M Thanks to the wide use of diagnostic imaging modalities, multiple primary malignancies are being diagnosed more frequently and different associations of malignancies have been reported in this setting. PMID: 21546703 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4824893 Mon, 16 May 2011 10:45:03 +0100 4824893 http://www.medworm.com/index.php?rid=4824892&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21546704%26dopt%3DAbstract Authors: Lightfoot N, Santos P, Nikfarjam M Paragangliomas are rare tumours of neural crest origin. Extra-adrenal pancreatic paragangliomas are exceptionally rare. PMID: 21546704 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4824892 Mon, 16 May 2011 10:45:03 +0100 4824892 http://www.medworm.com/index.php?rid=4824891&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21546705%26dopt%3DAbstract Authors: Igbinosa O Solid-cystic pseudopapillary tumor of the pancreas is a rare tumor, but has favorable prognosis even in the presence of distant metastases. It is often associated with diagnostic and therapeutic challenges. PMID: 21546705 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4824891 Mon, 16 May 2011 10:45:03 +0100 4824891 http://www.medworm.com/index.php?rid=4824890&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21546706%26dopt%3DAbstract Authors: Ghatak S, Ray S, Sanyal S, Sonar PK, Khamrui S, Basu K, Ray S, Das K Cystic lymphangioma of the pancreas presenting as acute abdomen in adults has not been reported before. PMID: 21546706 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4824890 Mon, 16 May 2011 10:45:03 +0100 4824890 http://www.medworm.com/index.php?rid=4824889&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21546707%26dopt%3DAbstract Authors: Puri Y, Rahman SH Colonic involvement is an uncommon but potentially lethal complication of severe acute pancreatitis and has received little attention in the surgical literature. Such complications can range from localized colonic pathology to widespread ischaemic pancolitis. Treatment options have historically been limited to resection of the affected segment. PMID: 21546707 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4824889 Mon, 16 May 2011 10:45:03 +0100 4824889 http://www.medworm.com/index.php?rid=4824888&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21546708%26dopt%3DAbstract Authors: Nuño-Guzmán CM, Arróniz-Jáuregui J, Gómez-Ontiveros JI, Hernández-Estrada H, Estrada-Castañeda HI, Araiza-Navarro JR, Esparza-Arias N A pancreatic pseudocyst is defined as a collection of pancreatic juice enclosed by a wall of fibrous or granulation tissue which is not lined by epithelium. Acute pseudocysts occur in acute pancreatitis but can be found after an acute exacerbation of chronic pancreatitis. Chronic pancreatic pseudocysts are typically found in chronic pancreatitis but may develop after an occurrence of acute pancreatitis as well. Most acute fluid collections and pseudocysts will show spontaneous resolution while the remaining may persist with or without symptoms, or progress to produce complications. Treatment is indicated for persistent, symptomatic pseudo... JOP journals http://www.medworm.com/rss/comments.php?id=4824888 Mon, 16 May 2011 10:45:03 +0100 4824888 http://www.medworm.com/index.php?rid=4824887&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21546709%26dopt%3DAbstract Authors: Horn AJ, Lele SM Epidermoid cysts occurring within intrapancreatic accessory spleens are exceptionally rare entities, with only 21 previously reported cases. Their clinical presentation prior to pathologic assessment can raise concern for possible malignancy; however, they behave in a benign fashion. PMID: 21546709 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4824887 Mon, 16 May 2011 10:45:03 +0100 4824887 http://www.medworm.com/index.php?rid=4824886&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21546710%26dopt%3DAbstract Authors: Rao RN, Vij M, Singla N, Kumar A Pancreatic extra-gastrointestinal stromal tumors are extremely uncommon neoplasm. To the best of our knowledge, only eleven cases have been reported in the literature. All the case reports published mostly involve diagnoses made on surgical pathology. PMID: 21546710 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4824886 Mon, 16 May 2011 10:45:03 +0100 4824886 http://www.medworm.com/index.php?rid=4824885&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21546711%26dopt%3DAbstract Authors: Patil PV, Khalil A, Thaha MA The close proximity of splenic hilum to the tail of pancreas makes it vulnerable to complications in both acute and chronic pancreatitis. In this article, we examine the clinical course of these potentially fatal complications. PMID: 21546711 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4824885 Mon, 16 May 2011 10:45:03 +0100 4824885 http://www.medworm.com/index.php?rid=4824884&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21546712%26dopt%3DAbstract We report a case of pancreatic acinar cell carcinoma associated with subcutaneous panniculitis together with a review of the English literature. PMID: 21546712 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4824884 Mon, 16 May 2011 10:45:03 +0100 4824884 http://www.medworm.com/index.php?rid=4824883&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21546713%26dopt%3DAbstract Authors: Nguyen VX, De Petris G, Nguyen BD Autoimmune pancreatitis is the pancreatic manifestation of a novel clinicopathological disorder called systemic IgG4-related sclerosing disease. Beside the pancreas, this entity affects other sites (salivary glands, orbit, lung, thyroid, gallbladder, biliary tree system, kidney, abdominal aorta, retroperitoneum, prostate, and lymph node) by infiltration with IgG4-positive plasma cells. Several case reports and small case series have demonstrated the utility of integrated positron emission tomography/computed tomography (PET/CT) in monitoring therapy and documenting relapse and flare-up of autoimmune pancreatitis. However, there are no reports on the usefulness of PET/CT in selecting extrapancreatic sites for tissue sampling. We herein demonstr... JOP journals http://www.medworm.com/rss/comments.php?id=4824883 Mon, 16 May 2011 10:45:03 +0100 4824883 http://www.medworm.com/index.php?rid=4824882&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21546714%26dopt%3DAbstract Authors: Saif MW, Brennan M, Penney R, Hotchkiss S, Kaley K Pancreatic cancer is known to metastasize rapidly. Liver and peritoneum are the most common sites of metastases in pancreatic cancer, followed by lungs, bones and brain. Less common sites of metastases such as muscle, skin, heart, pleura, stomach, umbilicus, kidney, appendix, spermatic cord and prostate have also been reported in pancreatic cancer. Cutaneous metastasis mostly occurs around umbilicus. A site other than umbilicus is rarely reported. The authors report a case of multiple skin metastases in a patient with primary pancreatic cancer and review the literature. PMID: 21546714 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4824882 Mon, 16 May 2011 10:45:03 +0100 4824882 http://www.medworm.com/index.php?rid=4824881&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21546715%26dopt%3DAbstract Authors: Pezzilli R, Fabbri D, Imbrogno A, Corinaldesi R PMID: 21546715 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4824881 Mon, 16 May 2011 10:45:03 +0100 4824881 http://www.medworm.com/index.php?rid=4722230&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21486178%26dopt%3DAbstract Conclusions: Even periodontally affected deciduous teeth can be treated successfully in PLS patients. Suppression of A.a. and a stringent maintenance program seem to be of high importance. PMID: 21486178 [PubMed - as supplied by publisher] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4722230 Mon, 11 Apr 2011 23:00:00 +0100 4722230 http://www.medworm.com/index.php?rid=4610683&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21386625%26dopt%3DAbstract Authors: Kang SP, Saif MW PMID: 21386625 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4610683 Sat, 19 Mar 2011 06:00:03 +0100 4610683 http://www.medworm.com/index.php?rid=4610682&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21386626%26dopt%3DAbstract Early Detection and Screening of Pancreatic Cancer. Highlights from the "2011 ASCO Gastrointestinal Cancers Symposium". San Francisco, CA, USA. January 20-22, 2011. JOP. 2011;12(2):83-5 Authors: Gonda TA, Saif MW Pancreatic cancer presents at an advanced stage in majority of the patients, hence resulting in a very dismal prognosis. Novel and effective methods to detect and screen pancreatic cancer and its precursors are warranted. The U.S. Multi-Society Task Force recommends against routine screening for pancreatic cancer in asymptomatic adults using abdominal palpation, ultrasonography, or serologic markers. Moreover, the screening for persons with hereditary predisposition to develop pancreatic cancer has not been validated. Herein, the authors summarize the data presented at... JOP journals http://www.medworm.com/rss/comments.php?id=4610682 Sat, 19 Mar 2011 06:00:03 +0100 4610682 http://www.medworm.com/index.php?rid=4610681&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21386627%26dopt%3DAbstract EUS-Guided Pancreatic Diagnosis and Beyond. Highlights from the "2011 ASCO Gastrointestinal Cancers Symposium". San Francisco, CA, USA. January 20-22, 2011. JOP. 2011;12(2):86-91 Authors: Vignesh S, Hoffe SE, Saif MW The therapeutic ability of endoscopic ultrasound has expanded, especially in assisting with radiation planning for image guided radiation techniques such as stereotactic body radiation therapy. Endoscopic ultrasound enables precise placement of fiducial markers into pancreatic cancers to accurately delineate the position of the target lesion as it moves with respiration. The authors summarize the data presented at the 2011 American Society of Clinical Oncology (ASCO) Gastrointestinal Cancers Symposium, including Abstracts #302, #327, #176, #182, and #349. PMID:... JOP journals http://www.medworm.com/rss/comments.php?id=4610681 Sat, 19 Mar 2011 06:00:03 +0100 4610681 http://www.medworm.com/index.php?rid=4610680&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21386628%26dopt%3DAbstract Identification of Prognostic and Predictive Markers in Pancreatic Adenocarcinoma. Highlights from the "2011 ASCO Gastrointestinal Cancers Symposium". San Francisco, CA, USA. January 20-22, 2011. JOP. 2011;12(2):92-5 Authors: Russo SM, Ove R, Saif MW Pancreatic cancer remains a significant cause of morbidity and mortality. While increasing treatment options have improved outcomes for many patients, they have also complicated decision-making for treatment. Unfortunately, most patients with pancreatic cancer die from their disease. Prognostic and predictive markers could play a role to improve treatment by identifying patients who may or may not require a given therapy, and determining those most likely to benefit from a therapy. At the 2011 American Society of Clinical Oncology (... JOP journals http://www.medworm.com/rss/comments.php?id=4610680 Sat, 19 Mar 2011 06:00:03 +0100 4610680 http://www.medworm.com/index.php?rid=4610679&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21386629%26dopt%3DAbstract First-Line Treatment for Advanced Pancreatic Cancer. Highlights from the "2011 ASCO Gastrointestinal Cancers Symposium". San Francisco, CA, USA. January 20-22, 2011. JOP. 2011;12(2):96-100 Authors: Oberstein PE, Saif MW Pancreatic adenocarcinoma remains a treatment-refractory cancer. Although pancreatic adenocarcinoma is only the 10th most common cause of new cancer in the United States, it is the fourth most common cause of cancer-related death. Most cases are not suitable for resection and a majority is metastatic at presentation. Gemcitabine, with or without erlotinib, has been the standard chemotherapy in this setting but the benefit is only modest. Because gemcitabine has been considered a standard treatment for advanced pancreatic cancer for the past decade, several rando... JOP journals http://www.medworm.com/rss/comments.php?id=4610679 Sat, 19 Mar 2011 06:00:03 +0100 4610679 http://www.medworm.com/index.php?rid=4610678&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21386630%26dopt%3DAbstract Locally Advanced Pancreatic Adenocarcinoma: Where Are We and Where Are We Going? Highlights from the "2011 ASCO Gastrointestinal Cancers Symposium". San Francisco, CA, USA. January 20-22, 2011. JOP. 2011;12(2):101-5 Authors: Chang BW, Saif MW Eight abstracts highlighting the continued evolution of the management of locally advanced pancreatic cancer were presented at the 2011 American Society of Clinical Oncology (ASCO) Gastrointestinal Cancers Symposium (Abstracts #195, #239, #259, #281, #287, #305, #307, #324). These studies address key issues including the role of novel targeted therapies, what chemotherapy regimen should be used in conjunction with radiotherapy, and whether locally advanced pancreatic cancer can be managed with chemotherapy alone. PMID: 21386630 [PubMed... JOP journals http://www.medworm.com/rss/comments.php?id=4610678 Sat, 19 Mar 2011 06:00:03 +0100 4610678 http://www.medworm.com/index.php?rid=4610677&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21386631%26dopt%3DAbstract Adjuvant Therapy of Pancreatic Cancer: Beyond Gemcitabine. Highlights from the "2011 ASCO Gastrointestinal Cancers Symposium". San Francisco, CA, USA. January 20-22, 2011. JOP. 2011;12(2):106-9 Authors: Saif MW There is no consensus on what constitutes "standard" adjuvant therapy for pancreatic cancer. This controversy derives from several studies, each fraught with its own limitations. Standards of care also vary somewhat on the geography as chemo-radiotherapy followed by chemotherapy or vice versa is considered the optimal therapy in North America (GITSG, RTOG) while chemotherapy alone is the current standard in Europe (ESPAC-1, CONKO, ESPAC-3). The high rate of locoregional failure following surgical resection for adenocarcinoma of the pancreas has made it clear that some fo... JOP journals http://www.medworm.com/rss/comments.php?id=4610677 Sat, 19 Mar 2011 06:00:03 +0100 4610677 http://www.medworm.com/index.php?rid=4610676&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21386632%26dopt%3DAbstract Treatment for Refractory Pancreatic Cancer. Highlights from the "2011 ASCO Gastrointestinal Cancers Symposium". San Francisco, CA, USA. January 20-22, 2011. JOP. 2011;12(2):110-3 Authors: Makrilia N, Syrigos KN, Saif MW While gemcitabine-based regimens are currently accepted as the standard first-line treatment of patients with locally advanced or metastatic pancreatic adenocarcinoma, there is no consensus regarding treatment in the second-line setting. This review is an update from the 2011 American Society of Clinical Oncology (ASCO) Gastrointestinal Cancers Symposium regarding recent developments in the treatment of refractory pancreatic cancer, as these were presented in Abstracts #237 and #272 of the meeting. PMID: 21386632 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4610676 Sat, 19 Mar 2011 06:00:03 +0100 4610676 http://www.medworm.com/index.php?rid=4610675&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21386633%26dopt%3DAbstract Novel Agents in the Management of Pancreatic Adenocarcinoma: Phase I Studies. Highlights from the "2011 ASCO Gastrointestinal Cancers Symposium". San Francisco, CA, USA. January 20-22, 2011. JOP. 2011;12(2):114-6 Authors: Dimou AT, Syrigos KN, Saif MW Pancreatic adenocarcinoma has repetitively proved refractory to chemotherapy and biologic compounds with only a few drugs offering limited benefit. A number of novel regimens has been tested in phase I trials and reported recently in the 2011 American Society of Clinical Oncology (ASCO) Gastrointestinal Cancers Symposium. Specifically, a novel mitogen-activated protein kinase kinase (MEK) inhibitor, a connective tissue growth factor inhibitor, a coagulase factor VIIa inhibitor, as well as adenovirus delivery of herpes simplex viru... JOP journals http://www.medworm.com/rss/comments.php?id=4610675 Sat, 19 Mar 2011 06:00:03 +0100 4610675 http://www.medworm.com/index.php?rid=4610674&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21386634%26dopt%3DAbstract Pancreatic Neuroendocrine Tumors: Role of Novel Agents. Highlights from the "2011 ASCO Gastrointestinal Cancers Symposium". San Francisco, CA, USA. January 20-22, 2011. JOP. 2011;12(2):117-9 Authors: Strimpakos AS, Syrigos KN, Saif MW Neuroendocrine tumors of pancreas (PNET) are very rare, consisting of heterogeneous histological subtypes with a variable natural history and different clinical manifestations. Although the vast majority of these neoplasms are sporadic, it is possible to be part of a genetic syndrome such as multiple endocrine neoplasia 1 (MEN-1) or tuberous sclerosis (TSC). When systemic treatment is required the options are limited and management strategy is generally based on experts' consensus or clinical experience. The prognosis is usually better than in pan... JOP journals http://www.medworm.com/rss/comments.php?id=4610674 Sat, 19 Mar 2011 06:00:03 +0100 4610674 http://www.medworm.com/index.php?rid=4610673&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21386635%26dopt%3DAbstract Translational Research in Pancreatic Cancer. Highlights from the "2011 ASCO Gastrointestinal Cancers Symposium". San Francisco, CA, USA. January 20-22, 2011. JOP. 2011;12(2):120-2 Authors: Strimpakos AS, Syrigos KN, Saif MW The high mortality rate of pancreatic cancer places this uncommon malignancy quite high as a cause of cancer related deaths. Compared to other solid tumors, there is a lag in the development of new effective drugs and the actual clinical benefit remains poor over the last decade or so. The lack of therapeutic options necessitates the invention of the important molecules playing role in pancreatic carcinogenesis and the development of specific targeted therapies. Treatment advances have to be proven first in the bench before applying them at the bedside, thus... JOP journals http://www.medworm.com/rss/comments.php?id=4610673 Sat, 19 Mar 2011 06:00:03 +0100 4610673 http://www.medworm.com/index.php?rid=4610672&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21386636%26dopt%3DAbstract Ampullary and Periampullary Tumors: Translational Efforts to Meet a Challenge in Diagnosis and Treatment. Highlights from the "2011 ASCO Gastrointestinal Cancers Symposium". San Francisco, CA, USA. January 20-22, 2011. JOP. 2011;12(2):123-5 Authors: Kang SP, Saif MW Ampullary adenocarcinoma is a rare diagnosis and often managed as carcinomas of pancreatobiliary origin. However, there is accumulating evidence unveiling attributes of ampullary carcinomas that are distinct from that of pancreas or biliary cancers. Growing translational efforts in understanding this rare disease are exemplified by Abstracts #161 and #204 presented at the 2011 American Society of Clinical Oncology (ASCO) Gastrointestinal Cancers Symposium. PMID: 21386636 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4610672 Sat, 19 Mar 2011 06:00:03 +0100 4610672 http://www.medworm.com/index.php?rid=4610671&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21386637%26dopt%3DAbstract Authors: Casadei R, Ricci C, Pezzilli R, Calculli L, D'Ambra M, Taffurelli G, Minni F The absence of a definition and a widely accepted ranking system to classify surgical complications has hampered proper interpretation of the surgical outcome. PMID: 21386637 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4610671 Sat, 19 Mar 2011 06:00:03 +0100 4610671 http://www.medworm.com/index.php?rid=4610670&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21386638%26dopt%3DAbstract Authors: Zhang YD, Yang Q, Jiang ZM, Ma W, Zhou SW, Xie de R In the last decade, gemcitabine-based regimen as first-line therapy has demonstrated low efficacy regarding overall survival benefit for patients with advanced pancreatic cancer. PMID: 21386638 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4610670 Sat, 19 Mar 2011 06:00:03 +0100 4610670 http://www.medworm.com/index.php?rid=4610669&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21386639%26dopt%3DAbstract Authors: Berselli M, Coppola S, Colombo C, Pennacchioli E, Fiore M, Gronchi A Resection of adjacent visceral organs is often required in surgery for abdominal mesenchymal tumors. PMID: 21386639 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4610669 Sat, 19 Mar 2011 06:00:03 +0100 4610669 http://www.medworm.com/index.php?rid=4610668&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21386640%26dopt%3DAbstract Authors: Ben-Ishay O, Ariche A, Lachter J, Kluger Y Metastatic and locally advanced disease is unfortunately a common clinical occurrence in patients affected by pancreatic cancer. The most frequent sites of metastasis are the liver and the peritoneal lining. The falciform and round ligaments are routinely resected and sent for pathology, but no metastases have ever been reported. PMID: 21386640 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4610668 Sat, 19 Mar 2011 06:00:03 +0100 4610668 http://www.medworm.com/index.php?rid=4610667&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21386641%26dopt%3DAbstract Authors: Goenka MK, Acharyya BC, Sethy PK, Goenka U Spontaneous rupture of the bile duct, although rare, has been described as a known surgical cause of jaundice in infancy after biliary atresia. PMID: 21386641 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4610667 Sat, 19 Mar 2011 06:00:03 +0100 4610667 http://www.medworm.com/index.php?rid=4610666&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21386642%26dopt%3DAbstract Authors: Gucer H, Bagci P, Coskunoglu EZ, Karadag C Heterotopia of the pancreas can be defined as the presence of pancreatic tissue in an abnormal location without any continuity with the main body of the pancreas. Heterotopic pancreatic tissue located in the gallbladder is a rare entity. Despite being a congenital condition, it takes years for heterotopic pancreas to become symptomatic. PMID: 21386642 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4610666 Sat, 19 Mar 2011 06:00:03 +0100 4610666 http://www.medworm.com/index.php?rid=4610665&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21386643%26dopt%3DAbstract Authors: Jarry J, Wagner T, Rault A, Sa Cunha A, Collet D Annular pancreas is an uncommon and rarely reported congenital anomaly which consists of a ring of pancreatic tissue encircling the duodenum. Despite the congenital nature of the disease, clinical manifestations may ensue at any age. PMID: 21386643 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4610665 Sat, 19 Mar 2011 06:00:03 +0100 4610665 http://www.medworm.com/index.php?rid=4610664&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21386644%26dopt%3DAbstract Authors: Terada T An autopsy case of cytomegalovirus (CMV) associated with fatal severe pancreatitis is reported. PMID: 21386644 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4610664 Sat, 19 Mar 2011 06:00:03 +0100 4610664 http://www.medworm.com/index.php?rid=4610663&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21386645%26dopt%3DAbstract We report a case of signet-ring cell carcinoma admixed with adenocarcinoma of the ampulla of Vater. Signet-ring cell carcinoma of the ampulla of Vater is rarely encountered in clinical practice. PMID: 21386645 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4610663 Sat, 19 Mar 2011 06:00:03 +0100 4610663 http://www.medworm.com/index.php?rid=4610662&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21386646%26dopt%3DAbstract Authors: Chawla S, Atten MJ, Attar BM Vasculitis is a known cause of pancreatitis and other gastrointestinal symptoms; however, most of these patients have medium vessel vasculitis like polyarteritis nodosa and often there are other associated conditions like hepatitis B or clinical manifestations that suggest the diagnosis. Wegener's granulomatosis is predominantly a reno-pulmonary disorder, rarely having gastrointestinal manifestations. PMID: 21386646 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4610662 Sat, 19 Mar 2011 06:00:03 +0100 4610662 http://www.medworm.com/index.php?rid=4610661&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21386647%26dopt%3DAbstract Authors: Maksymov V, Khalifa MA, Bussey A, Carter B, Hogan M Undifferentiated (anaplastic) carcinoma of the pancreas with osteoclast-like giant cells is exceedingly rare. The prognosis of undifferentiated carcinoma is worse than that of poorly differentiated ductal adenocarcinoma of the pancreas; however, undifferentiated carcinoma with osteoclast-like giant cells might have a more favorable prognosis. PMID: 21386647 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4610661 Sat, 19 Mar 2011 06:00:03 +0100 4610661 http://www.medworm.com/index.php?rid=4610660&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21386648%26dopt%3DAbstract Authors: Solanki R, Koganti SB, Bheerappa N, Sastry RA Inflammatory external pancreatic fistulas behave differently from postoperative external pancreatic fistulas in that the former are less likely to close without intervention and take a longer time to do so. The principal determinants of closure of an external pancreatic fistula are the anatomy of the fistulous tract (end versus side, main duct versus side branch), the presence of downstream ductal obstruction, ongoing peripancreatic inflammation and etiology of the fistula (inflammatory versus postoperative). While the approach to diagnosis and management of postoperative pancreatic fistulas has been standardized, the same is lacking for inflammatory external pancreatic fistulas, partly due to the absence of a unifying definition o... JOP journals http://www.medworm.com/rss/comments.php?id=4610660 Sat, 19 Mar 2011 06:00:03 +0100 4610660 http://www.medworm.com/index.php?rid=4610659&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21386649%26dopt%3DAbstract Authors: Adachi K Since the pancreas in the normal state is entirely devoid of squamous cells, squamous cell carcinoma of the pancreas is a controversial entity of uncertain origin. Reports of pancreatic carcinomas exhibiting a pure squamous morphology are very rarely described in the English literature. PMID: 21386649 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4610659 Sat, 19 Mar 2011 06:00:03 +0100 4610659 http://www.medworm.com/index.php?rid=4610658&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21386650%26dopt%3DAbstract Authors: Lai JM, Crowley P, Nikfarjam M Retroperitoneal lymph node enlargement in patients with pancreatic cancer is sometimes treated as incurable disease. Non-metastatic causes of lymphadenopathy should however be considered. PMID: 21386650 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4610658 Sat, 19 Mar 2011 06:00:03 +0100 4610658 http://www.medworm.com/index.php?rid=4610657&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21386651%26dopt%3DAbstract Authors: Gupta V, Kumar S, Kumar P, Chandra A Visceral artery pseudoaneurysms are uncommon. They most commonly affect the splenic artery and are secondary to chronic pancreatitis. Giant pseudoaneurysms (5 cm or larger in size) are rare and, until now, only 19 cases have been reported. PMID: 21386651 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4610657 Sat, 19 Mar 2011 06:00:03 +0100 4610657 http://www.medworm.com/index.php?rid=4610656&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21386652%26dopt%3DAbstract Authors: Machado NO, Chopra PJ, Al-Haddabi IH, Al-Qadhi H Duodenal gastrointestinal stromal tumors (GISTs) are uncommon and constitute a relatively small subset of GISTs which presents a unique dilemma having various surgical options. A case of a large ulcerating duodenal GIST arising from the second and third parts of the duodenum and involving the pancreas which was managed by a Whipple resection is presented. The literature is also reviewed to present the current status on surgical options, outcome, prognostic indicators and the role of imatinib mesylate in its management. PMID: 21386652 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4610656 Sat, 19 Mar 2011 06:00:03 +0100 4610656 http://www.medworm.com/index.php?rid=4610655&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21386653%26dopt%3DAbstract Authors: Vij M, Agrawal V, Pandey R Gastrointestinal stromal tumors are CD117 (C-Kit) positive mesenchymal neoplasms considered to originate from the interstitial cells of Cajal. Gastrointestinal stromal tumors have been described outside the gastrointestinal tract in sites, such as the mesentery, omentum and retroperitoneum; however, pancreatic extra-gastrointestinal stromal tumors are extremely rare and there have only been seven previous reports in the literature. PMID: 21386653 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4610655 Sat, 19 Mar 2011 06:00:03 +0100 4610655 http://www.medworm.com/index.php?rid=4610654&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21386654%26dopt%3DAbstract Authors: Solanki NS, Barreto SG PMID: 21386654 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4610654 Sat, 19 Mar 2011 06:00:03 +0100 4610654 http://www.medworm.com/index.php?rid=4610653&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21386655%26dopt%3DAbstract Authors: Pezzilli R, Fabbri D, Imbrogno A PMID: 21386655 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4610653 Sat, 19 Mar 2011 06:00:03 +0100 4610653 http://www.medworm.com/index.php?rid=4610652&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21398618%26dopt%3DAbstract Conclusion Simvastatin may overcome cetuximab resistance in colon cancer cells with KRAS mutations by modulating BRAF activity and inducing apoptosis. PMID: 21398618 [PubMed - as supplied by publisher] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4610652 Fri, 11 Mar 2011 00:00:00 +0100 4610652 http://www.medworm.com/index.php?rid=4548145&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21352964%26dopt%3DAbstract We report a case of Takotsubo syndrome occurring after emergent mitral valve replacement for acute infective endocarditis. The patient is a 66-year-old woman who regained complete recovery of left ventricular function. PMID: 21352964 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4548145 Tue, 01 Mar 2011 00:00:00 +0100 4548145 http://www.medworm.com/index.php?rid=4361374&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21206093%26dopt%3DAbstract Authors: Dimou A, Syrigos K, Saif MW The role of hedgehog pathway in the biology of pancreatic adenocarcinoma is an emerging area of investigation and provides a novel field for treatment intervention. Recent studies have shown the activation of the hedgehog pathway in pancreatic cancer. Despite the initial assumption of an autocrine mechanism, it seems that the hedgehog pathway contributes to the molecular conversation between tumor and its microenvironment through a paracrine loop. Furthermore, members of the hedgehog pathway crosstalk with other pathways; they regulate tumor angiogenesis and are associated with cancer stem cells. In addition, there is preclinical evidence about the efficiency of hedgehog inhibitors both in vitro and in vivo and the first clinical trials with those c... JOP journals http://www.medworm.com/rss/comments.php?id=4361374 Wed, 19 Jan 2011 00:30:04 +0100 4361374 http://www.medworm.com/index.php?rid=4361373&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21206094%26dopt%3DAbstract Authors: Johnstone KA, Diakogiannaki E, Dhayal S, Morgan NG, Harries LW Increased levels of circulating fatty acids deriving from over-nutrition are thought to contribute to the progressive beta-cell failure associated with type 2 diabetes. Pancreatic beta-cells in culture are sensitive to exposure to long-chain saturated fatty acids (e.g. palmitate) which cause cytotoxicity, whereas the monounsaturated equivalents (e.g. palmitoleate) are cytoprotective. PMID: 21206094 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4361373 Wed, 19 Jan 2011 00:30:04 +0100 4361373 http://www.medworm.com/index.php?rid=4361371&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21206095%26dopt%3DAbstract Authors: Girish BN, Rajesh G, Vaidyanathan K, Balakrishnan V Dietary proteins and amino acids can modulate pancreatic function. PMID: 21206095 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4361371 Wed, 19 Jan 2011 00:30:04 +0100 4361371 http://www.medworm.com/index.php?rid=4361370&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21206096%26dopt%3DAbstract Authors: Noor MT, Radhakrishna Y, Kochhar R, Ray P, Wig JD, Sinha SK, Singh K Severe acute pancreatitis is associated with high mortality with infectious complications being the most common cause of mortality. PMID: 21206096 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4361370 Wed, 19 Jan 2011 00:30:04 +0100 4361370 http://www.medworm.com/index.php?rid=4361369&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21206097%26dopt%3DAbstract Authors: Trikudanathan G, Philip A, Dasanu CA, Baker WL Infection with Helicobacter pylori (H. pylori) has been implicated in the etiopathogenesis of various malignant conditions. Notwithstanding, its etiological association with pancreatic cancer remains inconclusive. Studies focusing on the relationship between H. pylori infection and pancreatic cancer risk have yielded conflicting results. PMID: 21206097 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4361369 Wed, 19 Jan 2011 00:30:04 +0100 4361369 http://www.medworm.com/index.php?rid=4361368&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21206098%26dopt%3DAbstract Authors: Giakoustidis A, Cherian PT, Zen Y, Jassem W, Prachalias A, Srinivasan P, Heaton ND, Rela M With patients surviving longer after pancreatic resection, the challenges now is the management of the unresolved longer-term issues. PMID: 21206098 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4361368 Wed, 19 Jan 2011 00:30:04 +0100 4361368 http://www.medworm.com/index.php?rid=4361367&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21206099%26dopt%3DAbstract We report a case of pancreatic adenocarcinoma metastasising to the thyroid. We review the incidence, diagnosis, and management of this rare occurrence. PMID: 21206099 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4361367 Wed, 19 Jan 2011 00:30:04 +0100 4361367 http://www.medworm.com/index.php?rid=4361366&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21206100%26dopt%3DAbstract Authors: Patra KP, Scott LK Thrombocytopenia associated multiple organ failure is a rare but increasingly recognized condition in children. Diabetic ketoacidosis preceding thrombocytopenia associated multiple organ failure is previously unreported in pediatric patients. PMID: 21206100 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4361366 Wed, 19 Jan 2011 00:30:04 +0100 4361366 http://www.medworm.com/index.php?rid=4361365&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21206101%26dopt%3DAbstract Authors: Nasr JY, McGrath K Pancreatic cysts are increasingly detected incidentally, many of which are premalignant. Despite EUS-FNA and CEA level measurement, the diagnosis of a premalignant cyst may remain uncertain. PMID: 21206101 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4361365 Wed, 19 Jan 2011 00:30:04 +0100 4361365 http://www.medworm.com/index.php?rid=4361364&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21206102%26dopt%3DAbstract Authors: Levine RA, Bank MA Isolated traumatic injuries to the pancreas are extremely unusual and diagnosis may be difficult due to delay in presentation and subtlety of symptoms. PMID: 21206102 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4361364 Wed, 19 Jan 2011 00:30:04 +0100 4361364 http://www.medworm.com/index.php?rid=4361363&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21206103%26dopt%3DAbstract Authors: Petrou A, Papalambros A, Brennan N, Prassas E, Margariti T, Bramis K, Rozemberg T, Papalambros E Intraductal papillary mucinous neoplasms (IPMNs) are a recently classified pancreatic neoplasm with an increasing incidence. IPMN is often misdiagnosed as chronic pancreatitis because of symptoms of relapsing abdominal pain, pancreatitis, and steatorrhea and imaging findings of a dilated pancreatic duct of cystic lesions that are frequently confused with pseudocysts. Early recognition of IPMN allows for prompt surgical resection before malignant transformation. PMID: 21206103 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4361363 Wed, 19 Jan 2011 00:30:04 +0100 4361363 http://www.medworm.com/index.php?rid=4361362&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21206104%26dopt%3DAbstract Authors: Zemet R, Mazeh H, Neuman T, Freund HR, Eid A Perivascular epithelial cell tumors (PEComas) are a family of rare mesenchymal neoplasms which share cellular, immunohistochemical and ultrastructural characteristics but are found in different visceral and soft tissue sites. PEComas of the pancreas are extremely rare neoplasms. PMID: 21206104 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4361362 Wed, 19 Jan 2011 00:30:04 +0100 4361362 http://www.medworm.com/index.php?rid=4361361&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21206105%26dopt%3DAbstract Authors: Overbeck-Zubrzycka D, Lochan RJ, Balupuri S, Jackson RW, Charnley RM Pancreaticobronchial fistula is a rare complication of severe pancreatitis. Various diagnostic methods have been described previously. PMID: 21206105 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4361361 Wed, 19 Jan 2011 00:30:04 +0100 4361361 http://www.medworm.com/index.php?rid=4361360&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21206106%26dopt%3DAbstract Authors: Poves I, Burdio F, Alonso S, Seoane A, Grande L Primary adenocarcinoma of the duodenum is a rare digestive malignancy which is commonly treated by radical surgical resection, pancreaticoduodenectomy being the technique of choice. Complete tumor resection obtaining free margins should be the standard of treatment for primary adenocarcinoma of the duodenum. Segmental duodenal resection is an appropriate operation for selected cases of primary adenocarcinoma of the duodenum of the 3rd and 4th portions of the duodenum. PMID: 21206106 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4361360 Wed, 19 Jan 2011 00:30:04 +0100 4361360 http://www.medworm.com/index.php?rid=4361359&cid=s_30380_17_f&fid=30380&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21206107%26dopt%3DAbstract Authors: Saif MW, Hotchkiss S, Brennan M, Kaley K PMID: 21206107 [PubMed - in process] (Source: JOP) JOP journals http://www.medworm.com/rss/comments.php?id=4361359 Wed, 19 Jan 2011 00:30:04 +0100 4361359