MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Journal of Cancer Epidemiology' source. Thu, 09 Feb 2012 11:21:04 +0100 http://www.medworm.com/index.php?rid=5672688&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Foci%2F2012%2F482952%2F Concise and accessible approaches to pyrrolidine-2-ones were studied. The synthesis involves the conversion of erythruronolactone to pyrrolidine-2-ones in good yields. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5672688 Thu, 09 Feb 2012 16:00:39 +0100 5672688 http://www.medworm.com/index.php?rid=5663480&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fcri%2F2012%2F273604%2F A simple and sensitive thin-layer chromatographic method has been established for analysis of rasagiline mesylate in pharmaceutical dosage form. Chromatography on silica gel 60 F254 plates with 6 : 1 : 2(v/v/v) butanol-methanol water as mobile phase furnished compact spots at Rf  0.76±0.01. Densitometric analysis was performed at 254 nm. To show the specificity of the method, rasagiline mesylate was subjected to acid, base, neutral hydrolysis, oxidation, photolysis, and thermal decomposition, and the peaks of degradation products were well resolved from that of the pure drug. Linear regression analysis revealed a good linear relationship between peak area and amount of rasagiline mesylate in the range of 100–350 n... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5663480 Mon, 06 Feb 2012 15:52:53 +0100 5663480 http://www.medworm.com/index.php?rid=5663479&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fijta%2F2012%2F271758%2F Multiprotocol medical imaging communication through the Internet is more flexible than the tight DICOM transfers. This paper introduces a modular multiprotocol teleradiology architecture that integrates DICOM and common Internet services (based on web, FTP, and E-mail) into a unique operational domain. The extended WADO service (a web extension of DICOM) and the other proposed services allow access to all levels of the DICOM information hierarchy as opposed to solely Object level. A lightweight client site is considered adequate, because the server site of the architecture provides clients with service interfaces through the web as well as invulnerable space for temporary storage, called as User Domains, so that users fulfill their applications' tasks. The proposed teleradiology archit... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5663479 Mon, 06 Feb 2012 15:52:53 +0100 5663479 http://www.medworm.com/index.php?rid=5663478&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fijcb%2F2012%2F657423%2F We have previously demonstrated that a novel protein ZYG1 induces sexual cell fusion (zygote formation) of Dictyostelium cells. In the process of cell fusion, involvements of signal transduction pathways via Ca2+ and PKC (protein kinase C) have been suggested because zygote formation is greatly enhanced by PKC activators. In fact, there are several deduced sites phosphorylated by PKC in ZYG1 protein. Thereupon, we designed the present work to examine whether or not ZYG1 is actually phosphorylated by PKC and localized at the regions of cell-cell contacts where cell fusion occurs. These were ascertained, suggesting that ZYG1 might be the target protein for PKC. A humanized version of zyg1 cDNA (mzyg1) was introduced into myoblasts to know if ZYG1 is also effective in cell fusion of myoblasts... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5663478 Mon, 06 Feb 2012 15:52:53 +0100 5663478 http://www.medworm.com/index.php?rid=5663477&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fjfsa%2F2012%2F179015%2F Let L=−Δ+V be a Schrödinger operator on ℝn, where V∈Lloc1(ℝn) is a nonnegative function on ℝn. In this article, we show that the Hardy spaces L on product spaces can be characterized in terms of the Lusin area integral, atomic decomposition, and maximal functions. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5663477 Mon, 06 Feb 2012 15:52:53 +0100 5663477 http://www.medworm.com/index.php?rid=5663476&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fijcgt%2F2011%2F706893%2F With the rapid growth of digital photography, sharing of photos with friends and family has become very popular. When people share their photos, they usually organize them into albums according to events or places. To tell the story of some important events in one’s life, it is desirable to have an efficient summarization tool which can help people to receive a quick overview of an album containing large number of photos. In this paper, we present and analyze an approach for photo album summarization through a novel social game “Epitome” as a Facebook application. This social game can collect research data, and, at the same time, it provides a collage or a cover photo of the user’s photo album, while the user enjoys playing the game. The proof of concept of the ... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5663476 Mon, 06 Feb 2012 15:52:53 +0100 5663476 http://www.medworm.com/index.php?rid=5623906&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fcrim%2Fem%2F2012%2F380905%2F This case report refers to a victim of intraoperative cardiac arrest, who restored spontaneous circulation despite of cessation of cardiopulmonary resuscitation (CPR). The victim, a 53-year-old man, was undergoing a surgical investigation and rehabilitation of a thigh hematoma. Two minutes after discontinuation of a 46 min CPR, a normotensive sinus node rhythm appeared at monitor. Despite of lack of an adequate explanation, the authors believe that the combination of the high total dose of adrenaline with the cessation of mechanical ventilation might augment venous return and lead to restoration of spontaneous circulation. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5623906 Tue, 24 Jan 2012 16:28:40 +0100 5623906 http://www.medworm.com/index.php?rid=5623905&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fmi%2F2012%2F489810%2F Nanostructured, self-assembling peptides hold promise for a variety of regenerative medical applications such as 3D cell culture systems, accelerated wound healing, and nerve repair. The aim of this study was to determine whether the self-assembling peptide K5 can be applied as a carrier of anti-inflammatory drugs. First, we examined whether the K5 self-assembling peptide itself can modulate various cellular inflammatory responses. We found that peptide K5 significantly suppressed the release of tumor-necrosis-factor- (TNF-) α and prostaglandin E2 (PGE2) from RAW264.7 cells and peritoneal macrophages stimulated by lipopolysaccharide (LPS). Similarly, there was inhibition of cyclooxygenase- (COX-) 2 mRNA expression assessed by real-time PCR, indicating that the inhibition is at the tr... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5623905 Tue, 24 Jan 2012 16:28:40 +0100 5623905 http://www.medworm.com/index.php?rid=5623904&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fijic%2F2011%2F493942%2F A series of metal(II) complexes ML where M = VO(II), Co(II), Ni(II), Cu(II), and Zn(II) have been synthesized from azo Schiff base ligand (N′E)-N′-(5-((4-chlorophenyl)diazenyl)-2-hydroxybenzylidene)-2-hydroxybenzohydrazide and characterized on the basis of elemental analyses, electronic, IR, and 1H NMR spectra, magnetic susceptibility and also by aid of scanning electron microscopy (SEM), X-ray powder diffraction, fluorescence spectral studies, and molar conductivity measurements. Conductivity measurements reveal that the complexes are nonelectrolytes. Spectroscopy and other analytical studies reveal distorted square planar geometry for copper, square-pyramidal geometry for oxovanadium, and tetrahedral geometry for other complexes. Redox behavior of the copper(II) complex has... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5623904 Tue, 24 Jan 2012 16:28:40 +0100 5623904 http://www.medworm.com/index.php?rid=5623903&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fcrim%2Fvasmed%2F2011%2F818241%2F We report the first case of what we believe to be a spontaneous true maxillary artery aneurysm and its endovascular management. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5623903 Tue, 24 Jan 2012 16:28:40 +0100 5623903 http://www.medworm.com/index.php?rid=5623902&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fsrt%2F2012%2F839151%2F Brain infarction due to small vessel cerebrovascular disease (SVCD)—also known as small vessel infarct (SVI) or “lacunar” stroke—accounts for 20% to 25% of all ischemic strokes. Historically, SVIs have been associated with a favorable short-term prognosis. However, studies over the years have demonstrated that SVCD/SVI is perhaps a more complex and less benign phenomenon than generally presumed. The currently employed diagnostic and therapeutic strategies are based upon historical and contemporary perceptions of SVCD/SVI. What is discovered in the future will unmask the true countenance of SVCD/SVI and help furnish more accurate prognostication schemes and effective treatments for this condition. This paper is an overview of SVCD/SVI with respect to the disc... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5623902 Tue, 24 Jan 2012 16:28:40 +0100 5623902 http://www.medworm.com/index.php?rid=5602771&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fcrim%2Fanesthesiology%2F2011%2F841510%2F We present a case in which phaeochromocytoma was not diagnosed preoperatively despite extensive investigation. There was significant haemodynamic instability during surgery. We review current diagnostic criteria with a view to reducing such a risk in future. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5602771 Wed, 18 Jan 2012 17:01:46 +0100 5602771 http://www.medworm.com/index.php?rid=5602770&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fcrim%2Fnephrology%2F2011%2F672326%2F We report an especially rare case where a urethral catheter formed a knot around a double-J ureteral stent after a kidney transplantation. We will discuss the various risk factors for knotting of a catheter and the methods to untangle a knot. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5602770 Wed, 18 Jan 2012 17:01:46 +0100 5602770 http://www.medworm.com/index.php?rid=5602769&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fcrim%2Forthopedics%2F2011%2F412721%2F We describe a rare case of unilateral glenoid hypoplasia without instability and not involving humeral head. The patient was managed effectively with nonoperative measures that featured specific rehabilitation exercises for the shoulder. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5602769 Wed, 18 Jan 2012 17:01:46 +0100 5602769 http://www.medworm.com/index.php?rid=5602768&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fcggr%2F2012%2F359369%2F The molecular instructions that govern gene expression regulation are encoded in the genome and ultimately determine the morphology and functional specifications of the human brain. As a consequence, changes in gene expression levels might be directly related to the functional decline associated with brain aging. Small noncoding RNAs, including miRNAs, comprise a group of regulatory molecules that modulate the expression of hundred of genes which play important roles in brain metabolism. Recent comparative studies in humans and nonhuman primates revealed that miRNAs regulate multiple pathways and interconnected signaling cascades that are the basis for the cognitive decline and neurodegenerative disorders during aging. Identifying the roles of miRNAs and their target genes in model organis... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5602768 Wed, 18 Jan 2012 17:01:46 +0100 5602768 http://www.medworm.com/index.php?rid=5602767&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fjo%2F2012%2F590531%2F E-cadherin is one of the key molecules in the formation of cell-cell adhesion and interacts intracellularly with a group of proteins collectively named catenins, through which the E-cadherin-catenin complex is anchored to actin-based cytoskeletal components. Although cell-cell adhesion is often disrupted in cancer cells by either genetic or epigenetic alterations in cell adhesion molecules, disruption of cell-cell adhesion alone seems to be insufficient for the induction of cancer cell migration and invasion. A small GTP-binding protein, Rac1, induces the specific cellular protrusions lamellipodia via WAVE2, a member of WASP/WAVE family of the actin cytoskeletal regulatory proteins. Biochemical and pharmacological investigations have revealed that WAVE2 interacts with many proteins that re... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5602767 Wed, 18 Jan 2012 17:01:46 +0100 5602767 http://www.medworm.com/index.php?rid=5602766&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fsrcm%2F2012%2F987239%2F The Ewing sarcoma family of tumors (ESFT) represents an aggressive spectrum of malignant tumour types with common defining histological and cytogenetic features. To evaluate the functional activation of signal transducer and activator of transcription 3 (STAT3) in ESFT, we evaluated its activation in primary tissue sections and observed the functional consequences of its inhibition in ESFT cell lines. STAT3 was activated (tyrosine 705-phosphorylated) in 18 out of 31 primary tumours (58%), either diffusely (35%) or focally (23%). STAT3 was constitutively activated in 3 out of 3 ESFT cell lines tested, and its specific chemical inhibition resulted in complete loss of cell viability. STAT3 inhibition in ESFT cell lines was associated with several consistent changes in chemokine profile sugges... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5602766 Wed, 18 Jan 2012 17:01:46 +0100 5602766 http://www.medworm.com/index.php?rid=5602765&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fijd%2F2012%2F471380%2F Conclusions. The salivary pellicle seems to facilitate the adhesion of P. gingivalis and biofilm formation on orthodontic brackets, while the material comprising the brackets does not significantly impact on the number of bacteria. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5602765 Wed, 18 Jan 2012 17:01:46 +0100 5602765 http://www.medworm.com/index.php?rid=5602764&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fijic%2F2011%2F319757%2F 2D [H1,N15] HSQC NMR spectroscopy has been used to monitor reaction and product formation between [Pt(N15H3)2I2] and nucleic acids possessing irregular topologies and containing site-specific phosphorothioate substitution in the phosphodiester backbone. Comparison of the reaction profiles of dimer nucleic acids with and without phosphorothioate substitution is made with their short nucleic acid counterparts containing the key dimer components. Whereas d(GpA) is relatively unreactive towards [Pt(N15H3)2I2], NMR evidence suggests that the tandem sheared mismatch duplex d(GCG3pAGC)2 reacts to form the head-to-tail interstrand G3-N7-Pt-G3-N7 cross-link. The equivalent phosphorothioate R,S-d(GsA) reacts to form a monoiodo, monosulphur adduct, whereas the tandem sheared mismatch phosphorothioate... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5602764 Wed, 18 Jan 2012 17:01:46 +0100 5602764 http://www.medworm.com/index.php?rid=5548861&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fmpe%2F2011%2F262073%2F This paper presents and analyzes a strongly convergent approximate proximal point algorithm for finding zeros of maximal monotone operators in Hilbert spaces. The proposed method combines the proximal subproblem with a more general correction step which takes advantage of more information on the existing iterations. As applications, convex programming problems and generalized variational inequalities are considered. Some preliminary computational results are reported. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5548861 Thu, 29 Dec 2011 08:41:10 +0100 5548861 http://www.medworm.com/index.php?rid=5548860&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Faaa%2F2011%2F432963%2F Some new properties are obtained for generalized second-order contingent (adjacent) epiderivatives of set-valued maps. By employing the generalized second-order adjacent epiderivatives, necessary and sufficient conditions of Benson proper efficient solutions are given for set-valued optimization problems. The results obtained improve the corresponding results in the literature. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5548860 Thu, 29 Dec 2011 08:41:10 +0100 5548860 http://www.medworm.com/index.php?rid=5548859&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fijic%2F2011%2F624756%2F A novel thiosemicarbazone from 2-acetonaphthone (represented as acnTSC) has been synthesized and its basic coordination chemistry with zinc(II), cobalt(II), and copper(II) explored. The complexes were characterized by elemental analysis and various spectroscopic techniques and are best formulated as [M(acnTSC)2Cl2] with the metal likely in an octahedral environment. The anticancer activity of the complexes was determined against a panel of human colon cancer cells (HCT-116 and Caco-2). The compounds bind to DNA via an intercalative mode with binding constants of 9.7×104 M-1, 1.8×105 M-1, and 9.5×104 M-1 for the zinc, cobalt, and copper complexes, respectively. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5548859 Thu, 29 Dec 2011 08:41:10 +0100 5548859 http://www.medworm.com/index.php?rid=5548858&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fgrp%2F2011%2F784967%2F Conclusions. The results indicate that SELDI-TOF-MS can correctly distinguish node-positive CRC patients from node-negative ones and show great potential for preoperative screening for regional lymph node involvement of CRC. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5548858 Thu, 29 Dec 2011 08:41:10 +0100 5548858 http://www.medworm.com/index.php?rid=5415951&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fijeco%2F2011%2F685708%2F Social sustainability is a key concept introduced in recent decades by international environmental and forestry policies. The paper illustrates the process of stakeholder consultation for the definition of the objectives of the forest landscape plan conducted in a district of the Italian Apennines. Special attention was given to the farmers group, by reason of the great importance of wood pasture in the management system of this area. The results show that the majority of the interviewees feel a strong bond with their territory and with the traditional activities still carried out there, such as forest grazing. However, there are internal differences within the group, mostly linked to age and territory of origin. The multiple correspondence analysis (MCA) supported the investigation of the... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5415951 Thu, 17 Nov 2011 19:11:07 +0100 5415951 http://www.medworm.com/index.php?rid=5415950&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fjtm%2F2011%2F695382%2F Leishmaniases are parasitic diseases that spread in many countries with a prevalence of 12 million cases. There are few available treatments and antimonials are still of major importance in the therapeutic strategies used in most endemic regions. However, resistance toward these compounds has recently emerged in areas where the replacement of these drugs is mainly limited by the cost of alternative molecules. In this paper, we reviewed the studies carried out on antimonial resistance in Leishmania. Several common limitations of these works are presented before prevalent approaches to evidence antimonial resistance are related. Afterwards, phenotypic determination of resistance is described, then confronted to clinical outcome. Finally, we detail molecular mechanisms and targets involved in... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5415950 Thu, 17 Nov 2011 19:11:07 +0100 5415950 http://www.medworm.com/index.php?rid=5415949&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fcmmm%2F2011%2F287186%2F The ability of an oocyte to successfully mature is highly dependent on intrafollicular conditions, including the size and structure of the follicle. Here we present a mathematical model of oxygen transport in the antral follicle. We relate mean oxygen concentration in follicular fluid of bovine follicles to the concentration in the immediate vicinity of the cumulus-oocyte complex (COC). The model predicts that the oxygen levels within the antral follicle are dependent on the size and structure of the follicle and that the mean level of dissolved oxygen in follicular fluid does not necessarily correspond to that reaching the COC. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5415949 Thu, 17 Nov 2011 19:11:07 +0100 5415949 http://www.medworm.com/index.php?rid=5415948&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fau%2F2011%2F178312%2F Erectile dysfunction and urinary incontinence secondary to sphincter dysfunction are common conditions affecting many men worldwide with a negative effect on quality of life. They are encountered in a number of etiologies most commonly following radical prostatectomy in which they coexist in the same patient. Implantations of an artificial urinary sphincter and inflatable penile prosthesis have proven to be effective in the treatment of both conditions should conservative and minimally invasive measures fail. The recent literature has shown that dual implantation of these devices is feasible and safe with a durable clinical outcome. Once indicated, this can be done in a synchronous or nonsynchronous manner; however, the emerging of the single transverse scrotal incision as well as advancem... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5415948 Thu, 17 Nov 2011 19:11:07 +0100 5415948 http://www.medworm.com/index.php?rid=5415947&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fcrim%2Fobgyn%2F2011%2F157510%2F Conclusion. In this case, IFAC to block the reticuloendothelial system Fc receptor was successful. This procedure is promising as one of the treatment options for blood group incompatible pregnancy. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5415947 Thu, 17 Nov 2011 19:11:07 +0100 5415947 http://www.medworm.com/index.php?rid=5353993&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Farp%2F2011%2F317410%2F Conclusion. Isoflurane decreased the inflammatory response associated with OLV during thoracic surgery and may be preferable over propofol in patients with expected high levels of proinflammatory cytokines like cancer patients. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5353993 Thu, 27 Oct 2011 20:38:05 +0100 5353993 http://www.medworm.com/index.php?rid=5353992&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fcrim%2Fobgyn%2F2011%2F723467%2F Klippel-Trenaunay syndrome (KTS) is a rare congenital disease, and extensive cutaneous hemangiomas and abnormal venous vessels are characteristic. In our case, to manage her pregnancy with KTS, whole-body MRA was performed before delivery. A 29-year-old woman was referred at 28 weeks because of prominent vulvovaginal varicosities due to KTS. At 35 weeks, hypertrophy and multiple venous varicosities of her leg as well as massive vulvovaginal varicosities became prominent with a normal coagulation profile. Systematic MRAs revealed hemangiomas and varicosities in the right leg, the lower abdomen, and the pubic region, while no obvious AVM was detected around the bronchial tube and spine. We decided to deliver her baby by cesarean section at 37 weeks under general anesthesia, and a healthy bab... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5353992 Thu, 27 Oct 2011 20:38:05 +0100 5353992 http://www.medworm.com/index.php?rid=5329271&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fijn%2F2011%2F657051%2F In this study, we evaluated clearance and adverse events of iopamidol in PD patients. We measured the iopamidol concentration in the plasma, dialysate, and urine of 11 patients. Iopamidol clearance from patient plasma was delayed with a half-life of 33.3 h, and the elimination ratio was 83.6% for 96 h. We retrospectively investigated adverse events occurring in a total of 50 stable PD patients who underwent a total of 64 angiographic computed tomography (CT) scans. In 64 angiographic CT scans, two cases of adverse events were observed. Our results suggest that iopamidol can be eliminated by regular PD and careful observation for adverse events are necessary for the safe use of radiocontrast media. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5329271 Wed, 19 Oct 2011 15:02:52 +0100 5329271 http://www.medworm.com/index.php?rid=5329270&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Faaa%2F2011%2F175323%2F We analyze the stability of three classes of distributed order fractional differential equations (DOFDEs) with respect to the nonnegative density function. In this sense, we discover a robust stability condition for these systems based on characteristic function and new inertia concept of a matrix with respect to the density function. Moreover, we check the stability of a distributed order fractional WINDMI system to illustrate the validity of proposed procedure. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5329270 Wed, 19 Oct 2011 15:02:52 +0100 5329270 http://www.medworm.com/index.php?rid=5329269&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fcrp%2F2011%2F348527%2F Conclusion. Optimizing the AMI patients' delivery system to hospitals with on-site capacity of revascularization might enhance access to needed care thereby help to alleviate the prevailing variation in the rate of revascularization among New York City neighborhoods. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5329269 Wed, 19 Oct 2011 15:02:52 +0100 5329269 http://www.medworm.com/index.php?rid=5329268&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fcrim%2Fsurgery%2F2011%2F305914%2F A number of complications are reported with the use of intrauterine contraceptive devices. These may pursue asymptomatic course or present as an acute abdomen after migration into peritoneal cavity. The authors here are reporting an abdominal wall swelling caused by transuterine migration of a copper intrauterine contraceptive device in a 28-year-old female. An open approach was used, and impacted foreign body was retrieved. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5329268 Wed, 19 Oct 2011 15:02:52 +0100 5329268 http://www.medworm.com/index.php?rid=5329267&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Faaa%2F2011%2F208163%2F We prove the generalized Hyers-Ulam-Rassias stability of a general system of Euler-Lagrange-type quadratic functional equations in non-Archimedean 2-normed spaces and Menger probabilistic non-Archimedean-normed spaces. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5329267 Wed, 19 Oct 2011 15:02:52 +0100 5329267 http://www.medworm.com/index.php?rid=5329266&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fcrim%2Fsurgery%2F2011%2F509806%2F We present an interesting case where the offending foreign body gave rise to a diagnostic dilemma masquerading as a pancreatic mass. A high index of suspicion is indicated especially when dealing with atypical presentation and nonspecific symptoms as highlighted in this case. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5329266 Wed, 19 Oct 2011 15:02:52 +0100 5329266 http://www.medworm.com/index.php?rid=5329265&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fcrim%2Fid%2F2011%2F469194%2F Herpes virus type 2 DNA was detected by PCR in the cerebrospinal fluid in a young woman presenting with headache, stiff neck and pleocytosis, and serological findings consistent with reactivation. Since she was exposed to ticks, Lyme disease and tick-borne encephalitis were excluded. Further investigation in an ongoing project, using PCR and sequencing of the amplified products, showed the presence of Rickettsia helvetica in the cerebrospinal fluid. The bacteria were also isolated in Vero cell culture, and microimmunofluorescence confirmed the development of antibodies against Rickettsia spp. with predominance of IgM reactivity consistent with recent infection. She was treated with antibiotics and improved rapidly. The patient could easily have been judged to have isolated herpes meningiti... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5329265 Wed, 19 Oct 2011 15:02:52 +0100 5329265 http://www.medworm.com/index.php?rid=5329264&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fcrim%2Fpsychiatry%2F2011%2F258172%2F We present here a case whereby the patient had NMS and developed extensive deep venous thrombosis (DVT) despite being on standard DVT Prophylaxis. Our case illustrates that empiric intravenous heparin for the initial few days after the onset of NMS may be considered in those with high risk of VTE, as in such patients standard DVT prophylaxis may not be sufficient. To standardize as to which patients with NMS would be at the highest risk of VTE while on standard DVT prophylaxis, the role of a standardized scoring system and a double-blind randomized trial in the future would probably be beneficial. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5329264 Wed, 19 Oct 2011 15:02:52 +0100 5329264 http://www.medworm.com/index.php?rid=5329263&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fcrim%2F2011%2F671645%2F We present the case of a 63-year-old woman who initially presented in 1992 with a metastasis in the left calcaneus that led to the discovery of RCC. In 1998, a new metastasis was found in the ovary. In 2008, the diagnosis of a gallbladder metastasis was made. All metastases were surgically removed; no additional systemic therapies were used. Aggressive surgical treatment can prolong the survival of patients with resectable metastases. Patterns of metastasis are discussed, and a brief review of the literature is given regarding each localization. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5329263 Wed, 19 Oct 2011 15:02:52 +0100 5329263 http://www.medworm.com/index.php?rid=5329262&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fcrim%2Fpsychiatry%2F2011%2F797658%2F We describe a stable bipolar female patient on medications that got switched into mania due to higher doses of prednisone prescribed for her severe sinusitis. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5329262 Wed, 19 Oct 2011 15:02:52 +0100 5329262 http://www.medworm.com/index.php?rid=5329261&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fcrim%2Fsurgery%2F2011%2F491802%2F Spigelian hernias are rare hernias, representing only about 1-2% of all abdominal hernias. An accurate preoperative diagnosis of this condition is often difficult because the physical presence of these hernias is often not demonstrable owing to its peculiar anatomic location. Many patients with Spigelian hernias, therefore, may have no obvious findings on clinical examination. The diagnosis is even trickier in obese patients wherein the hernia sac may lie in an intraparietal plane, masked by the abdominal subcutaneous fat. Here we describe a case of incarcerated Spigelian hernia where clinical and radiological findings were inconsistent and the accurate diagnosis was made by laparoscopy and was followed by a laparoscopic-assisted repair using an open anterior approach with an onlay mes... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5329261 Wed, 19 Oct 2011 15:02:52 +0100 5329261 http://www.medworm.com/index.php?rid=5329260&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fcrim%2Forthopedics%2F2011%2F957196%2F We present a case of large osteochondral fracture of lateral femoral condyle involving the articular surface in a fifteen-year-old male with a positive history of significant weight gain of 5 kilograms in last six months. Blood investigations reported low vitamin D and testosterone levels with elevated alkaline phosphatase. Adequate exposure was achieved by doing Z-plasty of quadriceps apparatus. The fracture was treated with open reduction and internal fixation using Herbert's screws. Medical management in the form of vitamin D and calcium along with testosterone was given. After the surgery, full weight-bearing was allowed at three months. At one year followup, patient has good quadriceps function without any weakness of the muscle. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5329260 Wed, 19 Oct 2011 15:02:52 +0100 5329260 http://www.medworm.com/index.php?rid=5329259&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fjobes%2F2011%2F258051%2F This study examined the effects of Shiitake mushroom on the prevention of alterations of plasma lipid profiles, fat deposition, energy efficiency, and body fat index induced by HFD. Rats were given a low, medium, and high (7, 20, 60 g/kg = LD-M, MD-M, HD-M) Shiitake mushroom powder in their high-fat (50% in kcal) diets for 6 weeks. The results showed that the rats on the HD-M diet had the lowest body weight gain compared to MD-M and LD-M groups (P<0.05). The total fat deposition was significantly lower (−35%, P<0.05) in rats fed an HD-M diet than that of HFD group. Interestingly, plasma triacylglycerol (TAG) level was significantly lower (−55%, P<0.05) in rats on HD-M than HFD. This study also revealed the existence of negative correlat... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5329259 Wed, 19 Oct 2011 15:02:52 +0100 5329259 http://www.medworm.com/index.php?rid=5329258&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Frrp%2F2011%2F128353%2F In conclusion, rotator cuff tears did not significantly correlate with aortic calcification severity. This suggests that tendon ischemia may not be associated with the degree of macrovascular disease. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5329258 Wed, 19 Oct 2011 15:02:52 +0100 5329258 http://www.medworm.com/index.php?rid=5329257&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fcrim%2Fotolaryngology%2F2011%2F615210%2F We present a case of squamous cell carcinoma of the external auditory canal in 65-year-old Hispanic female who presented with a 6-month history of right ear pain, 3-month history of serosanguineous right ear drainage, and symptoms of facial paralysis. Due to the extensive spread of her tumor into the middle ear at the time of diagnosis, her tumor was deemed unresectable and she received palliative chemotherapy and radiation therapy and was sent to Alice Hospice and died several weeks later. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5329257 Wed, 19 Oct 2011 15:02:52 +0100 5329257 http://www.medworm.com/index.php?rid=5329256&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Femi%2F2011%2F813460%2F Conclusion. In this adequate powered longitudinal study, changes in tractive force during the different lunar phases did not influence the incidence of renal colic admissions in emergency department. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5329256 Wed, 19 Oct 2011 15:02:52 +0100 5329256 http://www.medworm.com/index.php?rid=5329255&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Faot%2F2011%2F213783%2F Cancer is one of the leading causes of death throughout the world. Advancements in early and improved diagnosis could help prevent a significant number of these deaths. Raman spectroscopy is a vibrational spectroscopic technique which has received considerable attention recently with regards to applications in clinical oncology. Raman spectroscopy has the potential not only to improve diagnosis of cancer but also to advance the treatment of cancer. A number of studies have investigated Raman spectroscopy for its potential to improve diagnosis and treatment of a wide variety of cancers. In this paper the most recent advances in dispersive Raman spectroscopy, which have demonstrated promising leads to real world application for clinical oncology are reviewed. The application of Raman spectro... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5329255 Wed, 19 Oct 2011 15:02:52 +0100 5329255 http://www.medworm.com/index.php?rid=5329254&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fijol%2F2011%2F508907%2F Conclusions. The present paper underlines the asymmetry, variability of the ethmoid roof, and the possible practical implications arising from that fact. The asymmetry of the roof of one side presents an additional point of consideration for careful preoperative and perioperative review of paranasal sinus CT scans in patients undergoing endonasal sinus surgery. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5329254 Wed, 19 Oct 2011 15:02:52 +0100 5329254 http://www.medworm.com/index.php?rid=5329253&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fheprt%2F2011%2F157089%2F Conclusion. Despite a good knowledge about HBV infection and vaccine, most of ORP are still not vaccinated. Hepatitis B vaccination should be a prerequisite for working in the theatre, hence putting surgical patients at reduced risk. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5329253 Wed, 19 Oct 2011 15:02:52 +0100 5329253 http://www.medworm.com/index.php?rid=5329252&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fbcri%2F2011%2F198325%2F High- and low-angle X-ray diffraction studies of hard α-keratin have been studied, and various models have been proposed over the last 70 years. Most of these studies have been confined to one or two forms of alpha keratin. This high- and low-angle synchrotron fibre diffraction study extends the study to cover all available data for all known forms of hard α-keratin including hairs, fingernails, hooves, horn, and quills from mammals, marsupials, and a monotreme, and it confirms that the model proposed is universally acceptable for all mammals. A complete Bragg analysis of the meridional diffraction patterns, including multiple-time exposures to verify any weak reflections, verified the existence of a superlattice consisting of two infinite lattices and three finite lattices. ... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5329252 Wed, 19 Oct 2011 15:02:52 +0100 5329252 http://www.medworm.com/index.php?rid=5329251&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fcrim%2F2011%2F487875%2F Conclusion. This study concludes that surgical resection may result in survival benefit in selected patients with solitary adrenal metastasis from esophageal adenocarcinoma. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5329251 Wed, 19 Oct 2011 15:02:52 +0100 5329251 http://www.medworm.com/index.php?rid=5329250&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Famet%2F2011%2F170490%2F Aerosol light scattering measurements were carried out using a TSI 3563 Nephelometer at the Mace Head Atmospheric Research Station, on the west coast of Ireland from year 2001–2010. A strong seasonal trend in the aerosol light scattering coefficient at 550 nm (σscat), for clean marine air masses, is observed with a high σscat value, [average (geometric mean)] of 35.3 Mm−1 (29.5 Mm−1), in January and a low σscat value of 13.7 Mm−1 (10.2 Mm−1), in July. This near threefold increase in the σscat value during the winter season is because of the large contribution of wind-speed generated sea-salt particles in the marine boundary layer. A high positive correlation coefficient of 0.82 was found betwee... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5329250 Wed, 19 Oct 2011 15:02:52 +0100 5329250 http://www.medworm.com/index.php?rid=5329249&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fcrim%2Fnm%2F2011%2F209467%2F This case study followed one adolescent patient who underwent bilateral deep brain stimulation of the centromedian parafascicular complex (CM-Pf) for debilitating, treatment refractory Tourette's syndrome for a period of 1.5 years. Neurocognitive testing showed no significant changes between baseline and follow-up assessments. Psychiatric assessment revealed positive outcomes in overall adaptive functioning and reduction in psychotropic medication load in this patient. Furthermore, despite significant baseline psychiatric comorbidity, this patient reported no suicidal ideation following electrode implantation. Deep brain stimulation is increasingly being used in children and adolescents. This case reports on the positive neurologic and neuropsychiatric outcome of an adolescent male with bi... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5329249 Wed, 19 Oct 2011 15:02:52 +0100 5329249 http://www.medworm.com/index.php?rid=5329248&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fijbc%2F2011%2F325947%2F In this study, we investigated the pattern of homozygous deletion that target the FHIT gene exons 3 to 9 genomic structure in Egyptian breast cancer patients. We have found that 65% (40 out of 62) of the cases exhibited homozygous deletion in at least one FHIT exon. The incidence of homozygous deletion was not associated with patients’ clinicopathological parameters including patients’ age, tumour grade, tumour type, and lymph node involvement. Using correlation analysis, we have observed a strong correlation between homozygous deletions of exon 3 and exon 4 (P<0.0001). Deletions in exon 5 were positively correlated with deletions in exon 7 (P<0.0001), Exon 8 (P<0.027), and exon 9 (P=0.04). Additionally, a strong correlation was observed between exons... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5329248 Wed, 19 Oct 2011 15:02:52 +0100 5329248 http://www.medworm.com/index.php?rid=5329247&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fcrim%2Fpediatrics%2F2011%2F614054%2F Malaria remains an overwhelming problem in the tropical developing countries, with 300 to 500 million new cases and about a million deaths per year (Mishra et al., 2003). Malaria is a potentially life-threatening disease in the tropics. Jaundice is one of the severe manifestations of falciparum malaria. Its incidence (Mishra et al., 2003). varies between 10 and 45% in different reports and is seen more in adults than in children. Jaundice may vary from mild to very severe. However, clinical signs of hepatic encephalopathy (such as liver flaps) are never seen unless there is presence of concomitant viral hepatitis (WHO, 2000). Our case is a 6-year-old female child presented with fever, jaundice, and anasarca. Peripheral smear showed trophozoites and schizonts of Plasmodium (P.) vivax an... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5329247 Wed, 19 Oct 2011 15:02:52 +0100 5329247 http://www.medworm.com/index.php?rid=5320302&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fppar%2F2011%2F179454%2F Growing evidence indicates that PPARγ agonists, including rosiglitazone (RSG), induce adipose mitochondrial biogenesis. By systematically analyzing mitochondrial gene expression in two common murine adipocyte models, the current study aimed to further establish the direct role of RSG and capture temporal changes in gene transcription. Microarray profiling revealed that in fully differentiated 3T3-L1 and C3H/10T1/2 adipocytes treated with RSG or DMSO vehicle for 1, 2, 4, 7, 24, and 48 hrs, RSG overwhelmingly increased mitochondrial gene transcripts time dependently. The timing of the increases was consistent with the cascade of organelle biogenesis, that is, initiated by induction of transcription factor(s), followed by increases in the biosynthesis machinery, and then by incre... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5320302 Sun, 16 Oct 2011 06:52:48 +0100 5320302 http://www.medworm.com/index.php?rid=5216757&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Femi%2F2011%2F616323%2F This study implies that higher BAC may lead to less severe injuries, without impacting mortality or length of hospital stay, however, further research is required to elucidate the nature of this relationship. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5216757 Wed, 14 Sep 2011 08:14:24 +0100 5216757 http://www.medworm.com/index.php?rid=5115866&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fsage%2Foncology%2F2011%2F728579%2F Cancers of the appendix are rare. Most of them are found accidentally on appendectomies performed for appendicitis. When reviewed, majority of the tumors were carcinoid, adenoma, and lymphoma. Adenocarcinomas of appendix are only 0.08% of all cancers and the treatment remains controversial. Here we are reporting a 46-year-old male presented with symptoms of appendicitis, diagnosed with adenocarcinoma of the appendix. The patient was treated with appendectomy and refused further surgical intervention to complete hemicolectomy. Up to date, he remains asymptomatic. We performed literature review of the tumors of the appendix. Most of the benign conditions are treated with surgery alone. Lymphomas require CHOP-like chemotherapy and carcinoid syndrome treatment with somatostatin analogues. ... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5115866 Thu, 11 Aug 2011 16:20:49 +0100 5115866 http://www.medworm.com/index.php?rid=5115865&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fjs%2F2011%2F735279%2F An interfacial capacitance measurement electrochemical technique has been used for the sensing of self-assembled DNA hairpin probes (M. tuberculosis and B. anthracis) attached to Au electrodes. The double-layer capacitance (Cdl) was determined with electrochemical perturbations from 0.2 V to 0.5 V versus Ag/AgCl at a Au/M. tuberculosis DNA hairpin probe at surface coverage Au electrodes. The capacitance study was done at pH 7, which was necessary to maintain the M. tuberculosis and B. anthracis DNA probes closed during the electrochemical perturbation. Detailed experimental analysis carried out by repetitively sw... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5115865 Thu, 11 Aug 2011 16:20:49 +0100 5115865 http://www.medworm.com/index.php?rid=5115864&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fsage%2Fpediatrics%2F2011%2F780745%2F A low-cost resource approach to ADHD therapy would be a practical approach to treating children in developing countries. Research has shown that ADHD is prevalent in all areas of the world, and yet treatment for children in more impoverished countries is still lacking. The approach taken was to combine yoga and meditation combined with multimodal behavioral therapy program for children ageing 6 to 11. The program was kept low cost by using trained high school volunteers and integrating the program within the public school. After 6 weeks of the program, 90.5% of children showed improvement as measured by their performance impairment score, a measurement of academic performance. Parent and Teacher evaluations of behavior also found improvement as 25 of the 64 children (39.1%) improve... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5115864 Thu, 11 Aug 2011 16:20:49 +0100 5115864 http://www.medworm.com/index.php?rid=5115863&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fsage%2Fma%2F2011%2F436045%2F We are concerned with the nonlinear (n+1)-term fractional integrodifferential inclusions L(D)u∈F(t,u,Tu,Su),   a.e.  t∈[0,1], where L(D)=Dα-bnDβn-bn-1Dβn-1-⋯-b1Dβ1, 0<β1<β2<⋯<βn-1<βn<1<α<2, b1,b2,…,bn are constant coefficients, and (Tu)(t)=∫01k(t,s)u(s)ds, (Su)(t)=∫0tl(t,s)u(s)ds, subject to the nonlocal conditions u(0)=0,   u(1)=∑i=1mγiu(ηi). The existence results are obtained by using two fixed-point theorems due to Bohnenblust-Karlin and Covitz-Nadler, respectively. Our results partly generalize and improve the known ones. (Source: J... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5115863 Thu, 11 Aug 2011 16:20:49 +0100 5115863 http://www.medworm.com/index.php?rid=5115862&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fjamop%2F2011%2F512841%2F The FT-Raman and FT-IR spectra for 1-bromo-2-chlorobenzene (1B2CB) have been recorded in the region 4000–100 cm−1 and compared with the harmonic vibrational frequencies calculated using HF/DFT (B3LYP) method by employing 6-31+G (d, p) and 6-311++G (d, p) basis set with appropriate scale factors. IR intensities and Raman activities are also calculated by HF and DFT (B3LYP) methods. Optimized geometries of the molecule have been interpreted and compared with the reported experimental values of some substituted benzene. The experimental geometrical parameters show satisfactory agreement with the theoretical prediction from HF and DFT. The scaled vibrational frequencies at B3LYP/6-311++G (d, p) seem to coincide with the experimentally observed values with acceptable devia... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5115862 Thu, 11 Aug 2011 16:20:49 +0100 5115862 http://www.medworm.com/index.php?rid=5115861&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fid%2F2011%2F674820%2F We present an infant affected by granulomatous chronic disease with acute haematogenous osteomyelitis of the fourth metacarpal. Serratia marcescens was found to be the pathogenic agent. Treatment was antibiotics and debridement. Bone healed with little length discrepancy but functional result was normal. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5115861 Thu, 11 Aug 2011 16:20:49 +0100 5115861 http://www.medworm.com/index.php?rid=5115860&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fsage%2Fendocrinology%2F2011%2F608056%2F Growth hormone deficiency (GHD) is a well-recognized clinical syndrome in adults. However, due to the high frequency of normal serum IGF-I levels in hypopituitary adults with GHD, it is now widely accepted that despite normal levels of total IGF-I, adults clinically suspected with GHD within the appropriate clinical setting must undergo GH provocative testing to confirm its diagnosis. Although the insulin tolerance test (ITT) is labor intensive, contraindicated in the elderly and in adults with seizure disorders and ischemic heart disease, can be unpleasant for the patient, and is potentially hazardous, this test remains the gold standard test for the biochemical demonstration of GHD in adults. In contrast, with the unavailability of the GHRH and arginine test as the alternative test to th... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5115860 Thu, 11 Aug 2011 16:20:49 +0100 5115860 http://www.medworm.com/index.php?rid=5115859&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fcrim%2F2011%2F681643%2F We present the case of an 80-year old man with a Stanford Type A dissecting thoracic aortic aneurysm plus the unusual CT finding of extramural haemorrhage along the pulmonary vessels. The clinical and radiological picture has an extremely high mortality (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5115859 Thu, 11 Aug 2011 16:20:49 +0100 5115859 http://www.medworm.com/index.php?rid=5115858&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fjt%2F2011%2F151596%2F Cigarette smoking and alcohol consumption possibly affect platelet functions. To verify the hypothesis that some α-, β-, and γ-carboline components in cigarette smoke and alcoholic beverages may change platelet aggregability, their effects on human platelets were determined by aggregometry together with investigating their membrane effects by turbidimetry. Carbolines inhibited platelet aggregation induced by five agents with the potency being 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole > 3-amino-1-methyl-5H-pyrido[4,3-b]indole > 1-methyl-9H-pyrido[3,4-b]indole. The most potent 3-amino-1,4-dimethyl-5H-pyrido[4,3-b]indole showed 50% aggregation-inhibitory concentrations of 6–172 μM. Both γ-carbolines interacted with phosphatidylchol... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5115858 Thu, 11 Aug 2011 16:20:49 +0100 5115858 http://www.medworm.com/index.php?rid=5115857&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fecam%2F2012%2F960128%2F In conclusion, SA-B inhibits the synthesis of Col I in LX-2 cells independent of TGF-β1 stimulation, and the anti-fibrotic effect of SA-B is due to direct inhibition of p38 signaling and inhibition the cross-talk of Smad to ERK signaling. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5115857 Thu, 11 Aug 2011 16:20:49 +0100 5115857 http://www.medworm.com/index.php?rid=5115856&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fendocrinology%2F2011%2F246872%2F We report what we believe to be the first documented case of endometrioid adenocarcinoma metastasizing to the thyroid gland. An 80-year-old woman was referred to the otolaryngology service with a rapidly growing neck mass. The mass appeared to originate from the thyroid gland. Her clinical presentation was consistent with anaplastic thyroid carcinoma. A tracheostomy was performed. An open biopsy established the diagnosis of moderately differentiated adenocarcinoma, consistent with a gynecologic primary. The patient had undergone a hysterectomy 5 years prior for endometrioid adenocarcinoma. The thyroid tumor histology and immunophenotype corresponded well with her prior endometrial carcinoma, indicating that the thyroid mass was a metastasis from the endometrial primary. Radiotherapy appear... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5115856 Thu, 11 Aug 2011 16:20:49 +0100 5115856 http://www.medworm.com/index.php?rid=5115855&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Faop%2F2011%2F565642%2F Conclusions. Range of motion improvement will be greatest between 2 weeks and 3 months, with improvement continuing until 12 months. Grip strength should return to near normal by one year. Function and pain will improve, but not return to normal by the end of 12 months. Clinical Relevance. These results provide the surgeon with information that can be shared with patients on the anticipated timeline for normal recovery of function and strength. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5115855 Thu, 11 Aug 2011 16:20:49 +0100 5115855 http://www.medworm.com/index.php?rid=5105726&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fijso%2F2011%2F374012%2F Individuals who carry an inherited mutation in the breast cancer 1 (BRCA1) and BRCA2 genes have a significant risk of developing breast and ovarian cancer over the course of their lifetime. As a result, there are important considerations for the clinician in the counseling, followup and management of mutation carriers. This review outlines salient aspects in the approach to patients at high risk of developing breast and ovarian cancer, including criteria for genetic testing, screening guidelines, surgical prophylaxis, and chemoprevention. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5105726 Mon, 08 Aug 2011 13:56:52 +0100 5105726 http://www.medworm.com/index.php?rid=5105725&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fcrim%2F2011%2F709264%2F Riedel's thyroiditis is a rare inflammatory disease of the thyroid gland and has been reported in 0.05% of thyroid surgeries. Herein we report two cases of Riedel's thyroiditis with variable clinical presentations. One of these cases was a 51-year-old man who was presented with hypothyroidism and the other a 17-year-old young male with thyrotoxicosis. In these cases, age may be a determining factor in presenting symptoms and signs, disease process, and response to treatment. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5105725 Mon, 08 Aug 2011 13:56:52 +0100 5105725 http://www.medworm.com/index.php?rid=5105724&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fsage%2Fgastroenterology%2F2011%2F719575%2F Esophageal cancer is often diagnosed at an advanced stage, with many patients found to have locoregional or metastatic disease at time of diagnosis. Because of this, cure may be unlikely, leading treatment efforts to focus more on symptom palliation and improving patient quality of life. The majority of patients with advanced disease suffer from some degree of dysphagia. Palliative efforts are therefore directed at relieving dysphagia, allowing patients to manage their oropharyngeal secretions, reduce aspiration risk, and maintain caloric intake orally. A variety of endoscopic treatment modalities have been utilized with these objectives in mind, with options determined by the location and size of the tumor, as well as the patient's expecte... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5105724 Mon, 08 Aug 2011 13:56:52 +0100 5105724 http://www.medworm.com/index.php?rid=5105723&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fsage%2Fdentistry%2F2011%2F870364%2F Conclusion. Our results suggest that utilization of a diode laser in combination with a photosensitizer may be useful for clinical treatment of periapical lesions. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5105723 Mon, 08 Aug 2011 13:56:52 +0100 5105723 http://www.medworm.com/index.php?rid=5105722&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fphys%2F2011%2F930406%2F Thermally stimulated depolarization current (TSDC) technique has been applied to investigate the dielectric properties of the HCl-doped ice. Three TSDC peaks were found from HCl-doped ice as well as ice of pure water. Among three peaks, the α and γ peaks are affected strongly by the concentrations of HCl. We found that the pH numbers are linearly proportioned to the ratios of the areas of the peaks. The relation between xα (the ratio of the area of α peak to the area of β peak) and pHHCl,α was found to be pHHCl,α=7.77−2.86xα. This result suggests the possibility of the development of an apparatus to measure the pH number of acid contaminated water. The activation energies correspond to depolarization processes reflected in the ... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5105722 Mon, 08 Aug 2011 13:56:52 +0100 5105722 http://www.medworm.com/index.php?rid=5105721&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fsage%2Fma%2F2011%2F630745%2F The existence of solution for a fourth-order nonlinear partial differential equation (PDE) class involving p-biharmonic operator Δ(|Δu|p−2Δu)=λρ(x)|u|q−2u  in  Ω,  u=Δu=0,  on⁡  ∂Ω, is proved by applying mountain pass theorem and a local minimization. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5105721 Mon, 08 Aug 2011 13:56:52 +0100 5105721 http://www.medworm.com/index.php?rid=5105720&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fdrt%2F2011%2F839743%2F Circadian factors might play a crucial role in the etiology of depression. It has been demonstrated that the disruption of circadian rhythms by lighting conditions and lifestyle predisposes individuals to a wide range of mood disorders, including impulsivity, mania and depression. Also, associated with depression, there is the impairment of circadian rhythmicity of behavioral, endocrine, and metabolic functions. Inspite of this close relationship between both processes, the complex relationship between the biological clock and the incidence of depressive symptoms is far from being understood. The efficiency and the timing of treatments based on chronotherapy (e.g., light treatment, sleep deprivation, and scheduled medication) indicate that the circadian system is an essential target in the... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5105720 Mon, 08 Aug 2011 13:56:52 +0100 5105720 http://www.medworm.com/index.php?rid=5093118&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fije%2F2011%2F493840%2F Adults with GH deficiency are known to exhibit reduced sweating. Whether sweating capacity is impacted in obese subjects with impaired GH secretion have not previously been investigated. The main objective was to investigate sweat secretion rate and the GH-IGF-I axis in obese subjects before and after weight loss. Sixteen severely obese women (BMI, 40.6 ± 1.1 kg/m2) were investigated before and after a diet-induced weight loss. Sixteen age-matched nonobese women served as controls. The obese subjects presented the characteristic decreased GH release, hyperinsulinaemia, increased FFA levels, and impaired insulin sensitivity, which all were normalised after diet-induced weight loss of 30 ± 5 kg. Sweat secretion rates were similar comparing obese and nonobese subje... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5093118 Thu, 04 Aug 2011 14:05:46 +0100 5093118 http://www.medworm.com/index.php?rid=5093117&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fsage%2Fpharmaceutics%2F2011%2F712196%2F In conclusion, the simultaneous intake of tea and FOSHUs that contain active peptides might affect daily self-antihypertensive management via enhancement or suppression of ACE inhibitory activity. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5093117 Thu, 04 Aug 2011 14:05:46 +0100 5093117 http://www.medworm.com/index.php?rid=5093115&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fijps%2F2011%2F109693%2F Reversible addition fragmentation chain transfer (RAFT) synthesis and self-assembly of free-base porphyrin cored star polymers are reported. The polymerization, in the presence of a free-base porphyrin cored chain transfer agent (CTA-FBP), produced porphyrin star polymers with controlled molecular weights and narrow polydispersities for a number of monomers including N, N-dimethylacrylamide (DMA) and styrene (St). Well-defined amphiphilic star block copolymers, P-(PS-PDMA)4 and P-(PDMA-PS)4 (P: porphyrin), were also prepared and used for self-assembly studies. In methanol, a selective solvent for PDMA, spherical micelles were observed for both block copolymers as characterized by TEM. UV-vis studies suggested star-like micelles were formed from P-(PS-PDMA)4, while P-(PDMA-PS)4 aggregated i... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5093115 Thu, 04 Aug 2011 14:05:46 +0100 5093115 http://www.medworm.com/index.php?rid=5093114&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fddns%2F2011%2F783136%2F Almost periodic solution of a three-species competition system with grazing rates and diffusions is investigated. By using the method of upper and lower solutions and Schauder fixed point theorem as well as Lyapunov stability theory, we give sufficient conditions to ensure the existence and globally asymptotically stable for the strictly positive space homogenous almost periodic solution, which extend and include corresponding results obtained by Q. C. Lin (1999), F. D. Chen and X. X. Chen (2003), and Y. Q. Liu, S. L, Xie, and Z. D. Xie (1996). (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5093114 Thu, 04 Aug 2011 14:05:46 +0100 5093114 http://www.medworm.com/index.php?rid=5093113&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fijpr%2F2011%2F873967%2F Undocumented migration is a (inferior) substitute to documented migration. Hence, policies affecting documented migration also affect undocumented migration. This paper explores this relationship from a theoretical perspective. The implications of this exploration are that lax enforcement of visa rules and national borders, combined with a very long waiting line (small annual quotas) for immigrant visas, can make illegal immigration a preferred option over legal immigration or, more generally, that for policy purposes all types of migrations should be regarded as interdependent. Therefore, policies aimed solely at, say, undocumented immigration will generally be less effective than an integrated policy approach. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5093113 Thu, 04 Aug 2011 14:05:46 +0100 5093113 http://www.medworm.com/index.php?rid=5093111&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fdrt%2F2011%2F909076%2F Previous research with the US inner-city youth demonstrated the hazardous effects of community violence exposure. It remains unclear, however, whether these findings are generalizable to other cultures and populations. Furthermore, the role of factors influencing the processing of traumatic events such as personality has not been investigated. Two groups of Russian adolescents (community youth (N=546) and male delinquents (N=352)) completed questionnaires assessing their exposure to community violence, conduct problems, internalizing psychopathology and personality. The study demonstrates that the relationships between exposure to violence and psychopathology are similar across different populations within the same culture (community youth and j... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5093111 Thu, 04 Aug 2011 14:05:46 +0100 5093111 http://www.medworm.com/index.php?rid=5093110&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fijmms%2F2011%2F154636%2F It is proved that if a ring R is semiabelian, then so is the skew polynomial ring R[x;σ], where σ is an endomorphism of R satisfying σ(e)=e for all e∈E(R). Some characterizations and properties of semiabelian rings are studied. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5093110 Thu, 04 Aug 2011 14:05:46 +0100 5093110 http://www.medworm.com/index.php?rid=5093109&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fjam%2F2011%2F393072%2F Both the forward and backward kinematics of the Gough-Stewart mechanism exhibit nonlinear behavior. It is critically important to take account of this nonlinearity in some applications such as path control in parallel kinematics machine tools. The nonlinearity of inverse kinematics is straightforward and has been first studied in this paper. However the nonlinearity of forward kinematics is more challenging to be considered as there is no analytic solution to the forward kinematic solution of the mechanism. A statistical approach including the Bates and Watts measures of nonlinearity has been employed to investigate the nonlinearity of the forward kinematics. The concept of standard sphere has been used to check the significance of the nonlinearity of the mechanism. It is demonstrated that... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5093109 Thu, 04 Aug 2011 14:05:46 +0100 5093109 http://www.medworm.com/index.php?rid=5093107&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fsage%2Fendocrinology%2F2011%2F832642%2F Db/db mice are overweight, dyslipidemic and develop diabetic complications, relevant for similar complications in human type 2 diabetes. We have used db/db and db/+ control mice to investigate alterations in proteinase expression and activity in circulation and kidneys by SDS-PAGE zymography, electron microscopy, immunohistochemistry, Western blotting, and in situ zymography. Plasma from db/db mice contained larger amounts of serine proteinases compared to db/+ mice. Kidneys from the db/db mice had a significantly larger glomerular surface area and somewhat thicker glomerular basement membranes compared to the db/+ mice. Furthermore, kidney extracts from db/+ mice contained metalloproteinases with Mr of approximately 92000, compatible with MMP-9, not observed in db/db mice. These results i... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5093107 Thu, 04 Aug 2011 14:05:46 +0100 5093107 http://www.medworm.com/index.php?rid=5093105&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fddns%2F2011%2F835321%2F We propose a discrete multispecies cooperation and competition predator-prey systems. For general nonautonomous case, sufficient conditions which ensure the permanence and the global stability of the system are obtained; for periodic case, sufficient conditions which ensure the existence of a globally stable positive periodic solution of the system are obtained. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5093105 Thu, 04 Aug 2011 14:05:46 +0100 5093105 http://www.medworm.com/index.php?rid=5093103&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fjam%2F2011%2F921835%2F The existence of the solution for a new system of generalized nonlinear mixed quasi variational inclusions with H-monotone operators is proved by using implicit resolvent technique, and the sensitivity analysis of solution in Hilbert spaces is given. Our results improve and generalize some results of the recent ones. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5093103 Thu, 04 Aug 2011 14:05:46 +0100 5093103 http://www.medworm.com/index.php?rid=5093101&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fijbi%2F2011%2F817250%2F The highly disordered refractive index distribution in skin causes multiple scattering of incident light and limits optical imaging and therapeutic depth. We hypothesize that localized mechanical compression reduces scattering by expulsing unbound water from the dermal collagen matrix, increasing protein concentration and decreasing the number of index mismatch interfaces between tissue constituents. A swept-source optical coherence tomography (OCT) system was used to assess changes in thickness and group refractive index in ex vivo porcine skin, as well as changes in signal intensity profile when imaging in vivo human skin. Compression of ex vivo porcine skin resulted in an effective strain of −58.5%, an increase in refractive index from 1.39 to 1.50, and a decrease in water volum... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5093101 Thu, 04 Aug 2011 14:05:46 +0100 5093101 http://www.medworm.com/index.php?rid=5067762&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fsage%2Fallergy%2F2011%2F493624%2F Conclusion. While it is still difficult to predict the long-term course of asthma, atopy remains the major risk factor for persistent asthma. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5067762 Wed, 27 Jul 2011 14:50:38 +0100 5067762 http://www.medworm.com/index.php?rid=5067761&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fijn%2F2011%2F609213%2F Renal diseases in mitochondrial cytopathies are a group of rare diseases that are characterized by frequent multisystemic involvement and extreme variability of phenotype. Most frequently patients present a tubular defect that is consistent with complete De Toni-Debré-Fanconi syndrome in most severe forms. More rarely, patients present with chronic tubulointerstitial nephritis, cystic renal diseases, or primary glomerular involvement. In recent years, two clearly defined entities, namely 3243 A > G tRNALEU mutations and coenzyme Q10 biosynthesis defects, have been described. The latter group is particularly important because it represents the only treatable renal mitochondrial defect. In this paper, the physiopathologic bases of mitochondrial cytopathies, the diagno... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5067761 Wed, 27 Jul 2011 14:50:38 +0100 5067761 http://www.medworm.com/index.php?rid=5067760&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fdte%2F2011%2F645609%2F We report a case of duodenal GIST, in which combined laparoendoscopic local resection was attempted. The lesion was resected endoscopically using endoscopic submucosal dissection technique under laparoscopic assistance. Laparoscope was used for originating the orientation of the tumor, intra-operative EUS, and monitoring serosal injury from the peritoneal cavity. Postoperative hemorrhage occurred; however, precise orientation of the lesion helped us to manage the patient with minimal invasive reoperation. And thus, the bowel integrity was completely preserved, by avoiding segmental duodenal resection and pancreaticoduodenectomy. This novel, less invasive surgical procedure may become an attractive option for the lesions originating in the anatomically challenging portion of the GI tract fo... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5067760 Wed, 27 Jul 2011 14:50:38 +0100 5067760 http://www.medworm.com/index.php?rid=5067759&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fjtm%2F2011%2F876742%2F Conclusion. The M&E toolkit is a useful instrument for detecting constraints in IRS operations and to trigger timely response. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5067759 Wed, 27 Jul 2011 14:50:38 +0100 5067759 http://www.medworm.com/index.php?rid=5067758&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Faaa%2F2011%2F602713%2F We prove some Hyers-Ulam stability results for an operator linear equation of the second order that is patterned on the difference equation, which defines the Lucas sequences (and in particular the Fibonacci numbers). In this way, we obtain several results on stability of some linear functional and differential and integral equations of the second order and some fixed point results for a particular (not necessarily linear) operator. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5067758 Wed, 27 Jul 2011 14:50:38 +0100 5067758 http://www.medworm.com/index.php?rid=5067757&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fsage%2Fgastroenterology%2F2011%2F580793%2F Conclusions. These results revealed that the prevalence of Giardiasis in dyspepsia and with diabetes mellitus was high in our country. This is the first study investigating the prevalence of Giardiasis in diabetic patients. To investigate Giardiasis in diabetic patients, who have dyspepsia or not, may be a good approach for public health. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5067757 Wed, 27 Jul 2011 14:50:38 +0100 5067757 http://www.medworm.com/index.php?rid=5067756&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fjnm%2F2011%2F476752%2F The layer-by-layer deposition method is utilized to prepare rodlike core/shell capsules. Chitosan (polycation) and chitosansulfate (polyanion) were alternatively deposited on the surface of calcium carbonate whisker (rodlike particle). The thickness of the obtained shells ranged from 26 to 42 nm. After the deposition, the shell was treated with diisocyanate to form crosslink between the chitosan or chitosansulfate chains in order to stabilize the deposited shell. The obtained shell crosslinked rodlike capsules were successfully converted to hollow particles by immersing them into hydrochloric acid due to the enhanced shell stability, whereas from noncrosslinked shells, no hollow capsules were yielded: the shell was removed by dissolution in hydrochloric acid. It is revealed that the... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5067756 Wed, 27 Jul 2011 14:50:38 +0100 5067756 http://www.medworm.com/index.php?rid=5067755&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fppar%2F2011%2F629728%2F Gene expression profiling of PPARα has been used in several studies, but fewer studies went further to identify the tissue-specific pathways or genes involved in PPARα activation in genome-wide. Here, we employed and applied gene set enrichment analysis to two microarray datasets both PPARα related respectively in mouse liver and intestine. We suggested that the regulatory mechanism of PPARα activation by WY14643 in mouse small intestine is more complicated than in liver due to more involved pathways. Several pathways were cancer-related such as pancreatic cancer and small cell lung cancer, which indicated that PPARα ... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5067755 Wed, 27 Jul 2011 14:50:38 +0100 5067755 http://www.medworm.com/index.php?rid=5067754&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Faans%2F2011%2F302572%2F This paper considers the applications of resampling methods to support vector machines (SVMs). We take into account the leaving-one-out cross-validation (CV) when determining the optimum tuning parameters and bootstrapping the deviance in order to summarize the measure of goodness-of-fit in SVMs. The leaving-one-out CV is also adapted in order to provide estimates of the bias of the excess error in a prediction rule constructed with training samples. We analyze the data from a mackerel-egg survey and a liver-disease study. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5067754 Wed, 27 Jul 2011 14:50:38 +0100 5067754 http://www.medworm.com/index.php?rid=5067753&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fjnt%2F2011%2F696535%2F The present study demonstrates an effect of nano-ZnO particles on the growth of plant seedlings of mung (Vigna radiate) and gram (Cicer arietinum). The study was carried out in plant agar media to prevent precipitation of water-insoluble nanoparticles in the test units. Various concentrations of nano-ZnO particles in suspension form were introduced to the agar media, and their effect on the root and shoot growth of the seedlings was examined. The main experimental approach, using correlative light and scanning electron microscopy provided evidence of adsorption of nanoparticles on the root surface. Absorption of nanoparticles by seedlings root was also detected by inductive coupled plasma/atomic emission spectroscopy (ICP-AES). It was found that at certain optimum concentration, the seedli... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5067753 Wed, 27 Jul 2011 14:50:38 +0100 5067753 http://www.medworm.com/index.php?rid=5067752&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fjr%2F2011%2F943137%2F Building a human-like robot that could be involved in our daily lives is a dream of many scientists. Achieving a sophisticated robot's vision system, which can enhance the robot's real-time interaction ability with the human, is one of the main keys toward realizing such an autonomous robot. In this work, we are suggesting a bioinspired vision system that helps to develop an advanced human-robot interaction in an autonomous humanoid robot. First, we enhance the robot's vision accuracy online by applying a novel dynamic edge detection algorithm abstracted from the rules that the horizontal cells play in the mammalian retina. Second, in order to support the first algorithm, we improve the robot's tracking ability by designing a variant photoreceptors distribution correspondin... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5067752 Wed, 27 Jul 2011 14:50:38 +0100 5067752 http://www.medworm.com/index.php?rid=5067751&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Famp%2F2011%2F138358%2F The quantum Langevin equation has been studied for dissipative system using the approach of Ford et al. Here, we have considered the inverted harmonic oscillator potential and calculated the effect of dissipation on tunneling time, group delay, and the self-interference term. A critical value of the friction coefficient has been determined for which the self-interference term vanishes. This approach sheds new light on understanding the ion transport at nanoscale. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5067751 Wed, 27 Jul 2011 14:50:38 +0100 5067751 http://www.medworm.com/index.php?rid=5067750&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fijqsr%2F2011%2F637079%2F This paper considers three competing maintenance actions: corrective after failure, condition-based preventive to avoid failure, and scheduled. A stochastic model is set for the time relationship between corrective and preventive maintenance. This model defines a version of the so-called random signs censoring, and it leads to natural goodness measures for condition control. The effect of condition control on important observable and unobservable indicators is studied. The latter half of the paper considers static Weibull models for the time to failure and the effect of condition control; the main contribution is a calculation method that derives the four model parameters from four figures of input data. Corresponding parameter experimentation is demonstrated on maintenance cost analysis a... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=5067750 Wed, 27 Jul 2011 14:50:38 +0100 5067750 http://www.medworm.com/index.php?rid=4930751&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fedr%2F2011%2F406182%2F Diabetes mellitus is a chronic disease with many debilitating complications. Treatment of diabetes mellitus mainly revolves around conventional oral hypoglycaemic agents and insulin replacement therapy. Recently, scientists have turned their attention to the generation of insulin-producing cells (IPCs) from stem cells of various sources. To date, many types of stem cells of human and animal origins have been successfully turned into IPCs in vitro and have been shown to exert glucose-lowering effect in vivo. However, scientists are still faced with the challenge of producing a sufficient number of IPCs that can in turn produce sufficient insulin for clinical use. A careful choice of stem cells, methods, and extrinsic factors for induction may all be contributing factors to successful produc... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=4930751 Thu, 16 Jun 2011 17:24:48 +0100 4930751 http://www.medworm.com/index.php?rid=4731018&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fisrn%2Fnursing%2F2011%2F672579%2F Sickle cell disease (SCD) is a chronic illness, and the major complication, pain, results in complex multidimensional problems that affect an individual's ability to maintain adequate quality of life in multiple areas. Chronic SCD pain is inadequately treated, because it is not well understood, and the degree of chronic pain, clinical presentation, and sequela complications can vary from patient to patient, even among individuals with the same SCD genotype. The reason for this variation is unknown, but the underlying cause might be genetic. Researchers have not explored the contribution of a genomic variable to the occurrence of heterogeneous chronic SCD pain. Previous research on the guanosine triphosphate cyclohydrolase (GCH1) gene suggests that in some cases, phenotypic heterogeneit... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=4731018 Wed, 20 Apr 2011 12:33:35 +0100 4731018 http://www.medworm.com/index.php?rid=4731017&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fisrn%2Fsurgery%2F2011%2F962186%2F Conclusions. Despite the risk of removing a histologically normal gland, we believe that when parathyroid “incidentalomas” are found during surgery they should be excised and sent for histological analysis. We have found this to be a safe procedure with minimal morbidity to the patient. As the natural history of primary hyperparathyroidism is better understood, these glands found in normocalcaemic patients may in fact represent the early or preclinical phase of the disease. By removing them at the original operation, the patient is saved redo neck surgery with its high complication rate as or when clinically apparent primary hyperparthryoidism develops in the future. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=4731017 Wed, 20 Apr 2011 12:33:35 +0100 4731017 http://www.medworm.com/index.php?rid=4731016&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fisrn%2Fme%2F2011%2F979532%2F To reduce computational effort of finite element (FE) calculations a corrugated sheet is replaced with an orthotropic plate. Analytical expressions for the mechanical properties are studied and compared to finite Element calculations in extension, free vibration, and buckling. Good similarity is shown in the stiffened and transverse direction of the corrugated sheet; however, the orthotropic models do not give an accurate twisting behavior. The stiffened direction of the corrugated sheet best matches the analytical expressions. Keeping in mind the presented limitation, the orthotropic model presented herein can be used to drastically reduce the number of elements needed when modelling corrugated sheet with finite elements. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=4731016 Wed, 20 Apr 2011 12:33:35 +0100 4731016 http://www.medworm.com/index.php?rid=4731015&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fsrcm%2F2011%2F130484%2F In this study we have used a genetically engineered mouse model for alveolar rhabdomyosarcoma (ARMS) which faithfully recapitulates the human disease by activating the pathognomic Pax3:Fkhr fusion gene and inactivating p53 in the maturing myoblasts. We have demonstrated that tumors from our mouse model of alveolar rhabdomyosarcoma express EGFR at both the mRNA and protein levels. We then tested the EGFR inhibitor, Erlotinib, for its efficacy in this mouse model of alveolar rhabdomyosarcoma. Surprisingly, Erlotinib had no effect on tumor progression, yet mice treated with Erlotinib showed 10–20% loss of body weight. These results suggest that EGFR might not be an a priori monotherapy target in alveolar rhabdomyosarcoma. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=4731015 Wed, 20 Apr 2011 12:33:35 +0100 4731015 http://www.medworm.com/index.php?rid=4722373&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fisrn%2Foc%2F2011%2F541082%2F The crystal structures of 4-(4-methylphenyl)-6-phenyl-2,3,3a,4-tetrahydro-1H-pyrido[3,2,1-jk]carbazole (IIa) and 4-(4-methoxyphenyl)-6-phenyl-2,3,3a,4-tetrahydro-1H-pyrido[3,2,1-jk]carbazole (IIb) were elucidated by single crystal X-ray diffraction. Compound (IIa), C28H25N, crystallizes in the triclinic system, space group P-1, with a=8.936(2) Å,b=10.490(1) Å,c=11.801(1) Å,α=102.69(5)°, β=103.27(3)°,γ=93.80(1)°, and Z=2. The compound (IIb), C28H25NO, crystallizes in the monoclinic system, space group P21/a, with a=11.376(5) Å,b=14.139(3) Å,c=13.237(4) Å,β=97.41(3)°, and Z=4. In both the structures, the pyrido ring adopts a twist boat conformatio... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=4722373 Sun, 17 Apr 2011 14:21:05 +0100 4722373 http://www.medworm.com/index.php?rid=4681850&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fjps%2F2011%2F497463%2F Power method polynomial transformations are commonly used for simulating continuous nonnormal distributions with specified moments. However, conventional moment-based estimators can (a) be substantially biased, (b) have high variance, or (c) be influenced by outliers. In view of these concerns, a characterization of power method transformations by L-moments is introduced. Specifically, systems of equations are derived for determining coefficients for specified L-moment ratios, which are associated with standard normal and standard logistic-based polynomials of order five and three. Boundaries for L-moment ratios are also derived, and closed-formed formulae are provided for determining if a power method distribution has a valid probability density function. It is demonstrated that L-moment ... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=4681850 Thu, 07 Apr 2011 14:34:46 +0100 4681850 http://www.medworm.com/index.php?rid=4681849&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fprt%2F2011%2F968218%2F Chronic pain is a major health concern that affects millions of people. There are no adequate long-term therapies for chronic pain sufferers, leading to significant cost for both society and the individual. The most commonly used therapy for chronic pain is the application of opioid analgesics and nonsteroidal anti-inflammatory drugs, but these drugs can lead to addiction and may cause side effects. Further studies of the mechanisms of chronic pain have opened the way for development of new treatment strategies, one of which is gene therapy. The key to gene therapy is selecting safe and highly efficient gene delivery systems that can deliver therapeutic genes to overexpress or suppress relevant targets in specific cell types. Here we review several promising viral vectors that could be app... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=4681849 Thu, 07 Apr 2011 14:34:46 +0100 4681849 http://www.medworm.com/index.php?rid=4640393&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fijped%2F2010%2F789183%2F Conclusions. We found statistically significant association between low-birth-weight and maternal sociodemographic status in Tuzla Canton during 1992–1995 war in Bosnia and Herzegovina. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=4640393 Mon, 28 Mar 2011 16:12:03 +0100 4640393 http://www.medworm.com/index.php?rid=4534988&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fmi%2F2010%2F158514%2F Our objective was to analyse the relationship between circulating cytokines, autoantibodies, acute phase reactants, and disease activity in DMARDs-naïve rheumatoid arthritis (RA) patients (n=140). All cytokines were significantly higher in the RA cohort than in healthy controls. Moderate-to-strong positive intercorrelations were observed between Th1/Th2/macrophage/fibroblast-derived cytokines. RF correlated significantly with IL-1β, IL-2, IL-4, IL-10, IL-12, G-CSF, GM-CSF, IFN-γ, and TNF (P<.0001), and aCCP and aMCV with IL-1β, IL-2, IL-4, and IL-10 (P<.0002), while IL-6 correlated best with the acute phase reactants, CRP, and SAA (P<.0001). In patients with a DAS28 score of ≥5.1, IFN-γ, IL-1β, IL-1Ra, TNF, GM-CSF, and VEG... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=4534988 Wed, 02 Mar 2011 10:37:58 +0100 4534988 http://www.medworm.com/index.php?rid=4534987&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fijp%2F2010%2F312580%2F In applications with low-energy conversion efficiency, maximizing the output power improves the efficiency. The maximum output power of a solar panel depends on the environmental conditions and load profile. In this paper, a method based on simultaneous use of two fuzzy controllers is developed in order to maximize the generated output power of a solar panel in a photovoltaic system: fuzzy-based sun tracking and maximum power point tracking. The sun tracking is performed by changing the solar panel orientation in horizontal and vertical directions by two DC motors properly designed. A DC-DC converter is employed to track the solar panel maximum power point. In addition, the proposed system has the capability of the extraction of solar panel I-V curves. Experimental results present that the... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=4534987 Wed, 02 Mar 2011 10:37:58 +0100 4534987 http://www.medworm.com/index.php?rid=4534986&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Farp%2F2011%2F521084%2F The aim of this experiment was to establish whether verapamil, nicardipine, and nitroglycerin have (1) infarct size-limiting effects and (2) antiarrhythmic effects in in vivo rabbit hearts during ischemia/reperfusion. Rabbits received regional ischemia by 30 min of left anterior descending coronary artery occlusion followed by 3 hours of reperfusion under ketamine and xylazine anesthesia. The animals were randomly assigned to the following 4 treatment groups: a control group, a verapamil group, a nicardipine group, and a nitroglycerin group. A continuous infusion of verapamil, nicardipine, or nitroglycerin was initiated 5 min prior to ischemia. Infarct size/area at risk decreased in verapamil, and nitroglycerin. The incidence of ischemia-induced arrhythmia decreased in nicard... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=4534986 Wed, 02 Mar 2011 10:37:58 +0100 4534986 http://www.medworm.com/index.php?rid=4534985&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fasp%2F2011%2F485738%2F Acoustic event detection (AED) aims at determining the identity of sounds and their temporal position in audio signals. When applied to spontaneously generated acoustic events, AED based only on audio information shows a large amount of errors, which are mostly due to temporal overlaps. Actually, temporal overlaps accounted for more than 70% of errors in the real-world interactive seminar recordings used in CLEAR 2007 evaluations. In this paper, we improve the recognition rate of acoustic events using information from both audio and video modalities. First, the acoustic data are processed to obtain both a set of spectrotemporal features and the 3D localization coordinates of the sound source. Second, a number of features are extracted from video recordings by means of object detection,... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=4534985 Wed, 02 Mar 2011 10:37:58 +0100 4534985 http://www.medworm.com/index.php?rid=4298088&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fjce%2F2010%2F569517.html Conclusions. ICD-9 codes were re-classified by group consensus into categories that are designed for oncology survivorship research. The novel re-classification system can be used by those involved in cancer survivorship research. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=4298088 Thu, 30 Dec 2010 07:40:00 +0100 4298088 http://www.medworm.com/index.php?rid=4292377&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fjce%2F2010%2F250606.html Conclusion. Our data suggest that inactivation of p53 may play an important role in the evolution of pleomorphic salivary adenoma and carcinoma ex pleomorphic adenoma. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=4292377 Wed, 29 Dec 2010 01:50:36 +0100 4292377 http://www.medworm.com/index.php?rid=3686125&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fjce%2F2010%2F824691.html Shorter survival has been associated with low socioeconomic status (SES) among elderly non-Hodgkin's lymphoma (NHL) patients; however it remains unknown whether the same relationship holds for younger patients. We explored the California Cancer Registry (CCR), to investigate this relationship in adolescent and young adult (AYA) NHL patients diagnosed from 1996 to 2005. A case-only survival analysis was conducted to examine demographic and clinical variables hypothesized to be related to survival. Included in the final analysis were 3,489 incident NHL cases. In the multivariate analyses, all-cause mortality (ACM) was higher in individuals who had later stage at diagnosis (P<.05) or did not receive first-course chemotherapy (P<.05). There was also a significant gradient dec... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=3686125 Wed, 23 Jun 2010 07:07:24 +0100 3686125 http://www.medworm.com/index.php?rid=3664943&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fjce%2F2010%2F509347.html Evidence independently links smoking, family history, and gender with increased risk of adenomatous polyps. Using data from the New Hampshire Colonoscopy Registry (2004–2006), we examined the relation of combined risk factors with adenoma occurrence in 5,395 individuals undergoing screening colonoscopy. Self-reported data on smoking, family history and other factors were linked to pathology reports identifying adenomatous polyps and modeled with multiple logistic regression. In adjusted models a >15 pack-year smoking history increased the likelihood of an adenoma (OR=1.54, 95% CI 1.28–1.86), although ≤15 pack-years did not (OR=1.07, 95% CI 0.87–1.32). Gender-stratified models showed a significantly increased risk of adenoma at lower smoking exposure eve... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=3664943 Wed, 16 Jun 2010 14:46:57 +0100 3664943 http://www.medworm.com/index.php?rid=3365556&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fjce%2F2009%2F354257.html Advances have been made in treatment and outcomes for pediatric cancer. However adolescents and young adults (AYAs) with cancer have not experienced similar relative improvements. We undertook a study to develop the methodology necessary for epidemiologic cancer research in these age groups. Our goal was to create the Kids, Adolescents, and Young Adults Cancer (KAYAC) project to create a resource to address research questions relevant to this population. We used a combination of clinic and population-based ascertainment to enroll 111 cases aged 0–39 for this methodology development study. The largest groups of cancer types enrolled include: breast cancer, leukemia, lymphoma, and melanoma. The overall participation rate is 69.8% and varies by age and tumor type. The study included... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=3365556 Mon, 15 Mar 2010 16:18:44 +0100 3365556 http://www.medworm.com/index.php?rid=3363498&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fjce%2F2009%2F591753.html This study examines the influence of sex on lymphoma risk in a relevant large animal model. Records for dogs in the Veterinary Medical Database were analyzed from 1964 to 2002. Risk ratios were calculated to evaluate associations between sex, neutering status, and lymphoma occurrence. A total of 14,573 cases and 1,157,342 controls were identified. Intact females had a significantly lower risk of developing lymphoma, Odds Ratio 0.69 (0.63–0.74) with a P<.001. We conclude that there is a sex effect on NHL risk in dogs similar to humans. We hypothesize that the hormone levels of intact females lower the risk of NHL. The possibility of a protective role of endogenous estrogens in the etiology of NHL should be investigated. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=3363498 Sun, 14 Mar 2010 15:51:09 +0100 3363498 http://www.medworm.com/index.php?rid=3282727&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fjce%2F2009%2F242151.html In a population-based case-control study, we explored the associations between 42 polymorphisms in seven genes in this region and non-small cell lung cancer (NSCLC) risk among Caucasian (364 cases; 380 controls) and African American (95 cases; 103 controls) women. Two TERT region SNPs, rs2075786 and rs2853677, conferred an increased risk of developing NSCLC, especially among African American women, and TERT-rs2735940 was associated with a decreased risk of lung cancer among African Americans. Five of the 20 GHR polymorphisms and SEPP1-rs6413428 were associated with a marginally increased risk of NSCLC among Caucasians. Random forest analysis reinforced the importance of GHR among Caucasians and identified AMACR, TERT, and GHR among African Americans, which were also significant using gene-... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=3282727 Thu, 18 Feb 2010 16:00:17 +0100 3282727 http://www.medworm.com/index.php?rid=3275080&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fjce%2F2009%2F182521.html There is uncertainty about risk heterogeneity for venous thromboembolism (VTE) in older patients with advanced cancer and whether patients can be stratified according to VTE risk. We performed a retrospective cohort study of the linked Medicare-Surveillance, Epidemiology, and End Results cancer registry in older patients with advanced cancer of lung, breast, colon, prostate, or pancreas diagnosed between 1995–1999. We used survival analysis with demographics, comorbidities, and tumor characteristics/treatment as independent variables. Outcome was VTE diagnosed at least one month after cancer diagnosis. VTE rate was highest in the first year (3.4%). Compared to prostate cancer (1.4 VTEs/100 person-years), there was marked variability in VTE risk (hazard ratio (HR) for ma... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=3275080 Tue, 16 Feb 2010 16:02:08 +0100 3275080 http://www.medworm.com/index.php?rid=3257815&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fjce%2F2009%2F354257.html Advances have been made in treatment and outcomes for pediatric cancer. However adolescents and young adults (AYAs) with cancer have not experienced similar relative improvements. We undertook a study to develop the methodology necessary for epidemiologic cancer research in these age groups. Our goal was to create the Kids, Adolescents, and Young Adults Cancer (KAYAC) project to create a resource to address research questions relevant to this population. We used a combination of clinic and population-based ascertainment to enroll 111 cases aged 0–39 for this methodology development study. The largest groups of cancer types enrolled include: breast cancer, leukemia, lymphoma, and melanoma. The overall participation rate is 69.8% and varies by age and tumor type. The study included... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=3257815 Wed, 10 Feb 2010 16:12:40 +0100 3257815 http://www.medworm.com/index.php?rid=2957961&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fjce%2F2009%2F302047.html Radiotherapy exerts part of its antineoplastic effect by generating oxidative stress, therefore genetic variation in oxidative stress-related enzymes may influence survival of rectal cancer patients. We hypothesized that genetic polymorphisms associated with higher amounts of reactive oxygen species (ROS) that exaggerate cytotoxic activity could improve survival after radiotherapy. We followed 114 rectal cancer patients who received radiotherapy for an average of 42.5 months. Associations between genotypes (GSTP1, GSTM1, GSTT1, CAT, MnSOD, MPO and eNOS) and overall survival were assessed using Kaplan-Meier curves and Cox proportional hazards regression. As hypothesized, patients carrying low ROS producing eNOS Glu298Asp asparagine allele showed an increased hazard of death compared to homo... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=2957961 Wed, 04 Nov 2009 16:11:40 +0100 2957961 http://www.medworm.com/index.php?rid=2930104&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fjce%2F2009%2F301973.html Retinoblastoma (Rb) is considered to represent the prototype of cancer linked to the sequential loss or inactivation of both alleles of a so-called “tumor suppressor gene”, the Rb1 gene. The pathogenetic mechanism behind this tumor was first hypothesized by Knudson in 1971 and further confirmed by others who identified the Rb1 gene whose loss or inactivation was claimed to be responsible for the disease. However, after about four decades of continuous research in the field of molecular biology, the evidence behind the role of the Rb1 gene in Rb appears to be seriously flawed in the light of epidemiological, biological, and clinical evidences. This editorial summarizes the inconsistencies on this subject. Nevertheless, the molecular biology establishment still adheres to the bia... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=2930104 Tue, 27 Oct 2009 15:55:56 +0100 2930104 http://www.medworm.com/index.php?rid=2501333&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fjce%2F2009%2F791754.html Lynch syndrome is mostly characterized by early-onset colorectal and endometrial adenocarcinomas. Over 90% of the causal mutations occur in two mismatch repair genes, MSH2 and MLH1. The aim of this study was to evaluate the age-dependent cancer risk in MSH2 or MLH1 mutation carriers from data of DNA diagnostic laboratories. To avoid overestimation, evaluation was based on the age-dependent proportion of mutation carriers in asymptomatic first-degree relatives of identified mutation carriers. Data from 859 such eligible relatives were collected from 8 centers; 387 were found to have inherited the mutation from their relatives. Age-dependent risks were calculated either using a nonparametric approach for four discrete age groups or assuming a modified Weibull distribution for the dep... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=2501333 Thu, 25 Jun 2009 08:43:02 +0100 2501333 http://www.medworm.com/index.php?rid=2467292&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fjce%2F2008%2F298495.html The majority of squamous cell carcinomas of cervix are preceded by visible changes in the cervix, most often detected by cervical smear. As cervical cancer is preceded by long precancerous stages, identification of the high-risk population through detection of DNA ploidy may be of importance in effective management of this disease. Here we attempted to correlate aneuploid DNA patterns and their influence on biological behavior of flow-cytometry analysis of DNA ploidy which was carried out in cytologically diagnosed cases of mild (79), moderate (36), and severe (12) dysplasia, as well as “atypical squamous cells of unknown significance (ASCUS)” (57) along with controls (69), in order to understand its importance in malignant progression of disease. Cytologically diagnosed dyspla... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=2467292 Wed, 10 Jun 2009 01:20:15 +0100 2467292 http://www.medworm.com/index.php?rid=2467291&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fjce%2F2008%2F147905.html Apoptotic capacity (AC) in primary lymphocytes may be a marker for cancer susceptibility, and functional single nucleotide polymorphisms (SNPs) in genes involved in apoptotic pathways may modulate cellular AC in response to DNA damage. To further examine the correlation between apoptotic genotypes and phenotype, we genotyped 14 published SNPs in 11 apoptosis-related genes (i.e., p53, Bcl-2, BAX, CASP9, DR4, Fas, FasL, CASP8, CASP10, CASP3, and CASP7) and assessed the AC in response to benzo[a]pyrene-7,8-9,10-diol epoxide (BPDE) in cultured primary lymphocytes from 172 cancer-free subjects. We found that among these 14 SNPs, R72P, intron 3 16-bp del/ins, and intron 6 G>A in p53, −938C>A in Bcl-2, and I522L in CASP10 were significant predictors of the BPDE-induced lymphocytic... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=2467291 Wed, 10 Jun 2009 01:20:15 +0100 2467291 http://www.medworm.com/index.php?rid=2467290&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fjce%2F2008%2F215809.html Both genetic and epigenetic alterations characterize human nonsmall cell lung cancer (NSCLC), but the biological processes that create or select these alterations remain incompletely investigated. Our hypothesis posits that a roughly reciprocal relationship between the propensity for promoter hypermethylation and a propensity for genetic deletion leads to distinct molecular phenotypes of lung cancer. To test this hypothesis, we examined promoter hypermethylation of 17 tumor suppressor genes, as a marker of epigenetic alteration propensity, and deletion events at the 3p21 region, as a marker of genetic alteration. To model the complex biology between these somatic alterations, we utilized an item response theory model. We demonstrated that tumors exhibiting LOH at greater than 30% of in... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=2467290 Wed, 10 Jun 2009 01:20:15 +0100 2467290 http://www.medworm.com/index.php?rid=2467289&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fjce%2F2009%2F791754.html Lynch syndrome is mostly characterized by early-onset colorectal and endometrial adenocarcinomas. Over 90% of the causal mutations occur in two mismatch repair genes, MSH2 and MLH1. The aim of this study was to evaluate the age-dependent cancer risk in MSH2 or MLH1 mutation carriers from data of DNA diagnostic laboratories. To avoid overestimation, evaluation was based on the age-dependent proportion of mutation carriers in asymptomatic first-degree relatives of identified mutation carriers. Data from 859 such eligible relatives were collected from 8 centers; 387 were found to have inherited the mutation from their relatives. Age-dependent risks were calculated either using a nonparametric approach for four discrete age groups or assuming a modified Weibull distribution for the dep... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=2467289 Wed, 10 Jun 2009 01:20:15 +0100 2467289 http://www.medworm.com/index.php?rid=2467288&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fjce%2F2008%2F387423.html Nonsynonymous SNPs (nsSNPs) in DNA repair genes may be important determinants of DNA damage and cancer risk. We applied a set of screening criteria to a large number of nsSNPs and selected a subset of SNPs that were likely candidates for phenotypic effects on DNA double-strand break repair (DSBR). In order to induce and follow DSBR, we exposed panels of cell lines to gamma irradiation and followed the formation and disappearance of γH2A.X foci over time. All panels of cell lines showed significant increases in number, intensity, and area of foci at both the 1-hour and 3-hour time points. Twenty four hours following exposure, the number of foci returned to preexposure levels in all cell lines, whereas the size and intensity of foci remained significantly elevated. We saw no significa... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=2467288 Wed, 10 Jun 2009 01:20:15 +0100 2467288 http://www.medworm.com/index.php?rid=2467287&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2Fjournals%2Fjce%2F2009%2F748367.html In conclusion, weight history did affect breast cancer risk. Moreover, smoking appeared to raise the risk, whereas moderate physical activity had a protective effect. (Source: Journal of Cancer Epidemiology) Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=2467287 Wed, 10 Jun 2009 01:20:15 +0100 2467287 http://www.medworm.com/index.php?rid=2256316&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2FGetArticle.aspx%3Fdoi%3D10.1155%2F2008%2F387423 Nonsynonymous SNPs (nsSNPs) in DNA repair genes may be important determinants of DNA damage and cancer risk. We applied a set of screening criteria to a large number of nsSNPs and selected a subset of SNPs that were likely candidates for phenotypic effects on DNA double-strand break repair (DSBR). In order to induce and follow DSBR, we exposed panels of cell lines to gamma irradiation and followed the formation and disappearance of γH2A.X foci over time. All panels of cell lines showed significant increases in number, intensity, and area of foci at both the 1-hour and 3-hour time points. Twenty four hours following exposure, the number of foci returned to preexposure levels in all cell lines, whereas the size and intensity of foci remained significantly elevated. We saw no significa... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=2256316 Thu, 12 Mar 2009 22:40:10 +0100 2256316 http://www.medworm.com/index.php?rid=2249874&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2FGetArticle.aspx%3Fdoi%3D10.1155%2F2009%2F791754 Lynch syndrome is mostly characterized by early-onset colorectal and endometrial adenocarcinomas. Over 90% of the causal mutations occur in two mismatch repair genes, MSH2 and MLH1. The aim of this study was to evaluate the age-dependent cancer risk in MSH2 or MLH1 mutation carriers from data of DNA diagnostic laboratories. To avoid overestimation, evaluation was based on the age-dependent proportion of mutation carriers in asymptomatic first-degree relatives of identified mutation carriers. Data from 859 such eligible relatives were collected from 8 centers; 387 were found to have inherited the mutation from their relatives. Age-dependent risks were calculated either using a nonparametric approach for four discrete age groups or assuming a modified Weibull distribution for the dep... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=2249874 Mon, 09 Mar 2009 05:41:56 +0100 2249874 http://www.medworm.com/index.php?rid=2142069&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2FGetArticle.aspx%3Fdoi%3D10.1155%2F2008%2F215809 Both genetic and epigenetic alterations characterize human nonsmall cell lung cancer (NSCLC), but the biological processes that create or select these alterations remain incompletely investigated. Our hypothesis posits that a roughly reciprocal relationship between the propensity for promoter hypermethylation and a propensity for genetic deletion leads to distinct molecular phenotypes of lung cancer. To test this hypothesis, we examined promoter hypermethylation of 17 tumor suppressor genes, as a marker of epigenetic alteration propensity, and deletion events at the 3p21 region, as a marker of genetic alteration. To model the complex biology between these somatic alterations, we utilized an item response theory model. We demonstrated that tumors exhibiting LOH at greater than 30% of in... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=2142069 Thu, 29 Jan 2009 16:20:46 +0100 2142069 http://www.medworm.com/index.php?rid=1915510&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2FGetArticle.aspx%3Fdoi%3D10.1155%2F2008%2F147905 Apoptotic capacity (AC) in primary lymphocytes may be a marker for cancer susceptibility, and functional single nucleotide polymorphisms (SNPs) in genes involved in apoptotic pathways may modulate cellular AC in response to DNA damage. To further examine the correlation between apoptotic genotypes and phenotype, we genotyped 14 published SNPs in 11 apoptosis-related genes (i.e., p53, Bcl-2, BAX, CASP9, DR4, Fas, FasL, CASP8, CASP10, CASP3, and CASP7) and assessed the AC in response to benzo[a]pyrene-7,8-9,10-diol epoxide (BPDE) in cultured primary lymphocytes from 172 cancer-free subjects. We found that among these 14 SNPs, R72P, intron 3 16-bp del/ins, and intron 6 G>A in p53, −938C>A in Bcl-2, and I522L in CASP10 were significant predictors of the BPDE-induced lymphocytic... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=1915510 Wed, 29 Oct 2008 16:14:11 +0100 1915510 http://www.medworm.com/index.php?rid=1489680&cid=s_37032_54_f&fid=37032&url=http%3A%2F%2Fwww.hindawi.com%2FGetArticle.aspx%3Fdoi%3D10.1155%2F2008%2F298495 The majority of squamous cell carcinomas of cervix are preceded by visible changes in the cervix, most often detected by cervical smear. As cervical cancer is preceded by long precancerous stages, identification of the high-risk population through detection of DNA ploidy may be of importance in effective management of this disease. Here we attempted to correlate aneuploid DNA patterns and their influence on biological behavior of flow-cytometry analysis of DNA ploidy which was carried out in cytologically diagnosed cases of mild (79), moderate (36), and severe (12) dysplasia, as well as “atypical squamous cells of unknown significance (ASCUS)” (57) along with controls (69), in order to understand its importance in malignant progression of disease. Cytologically diagnosed dyspla... Journal of Cancer Epidemiology journals http://www.medworm.com/rss/comments.php?id=1489680 Tue, 03 Jun 2008 22:24:00 +0100 1489680