Journal of Gastroenterology and Hepatology via MedWorm.com MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Journal of Gastroenterology and Hepatology' source. Mon, 15 Mar 2010 14:33:05 +0100 Percutaneous radiofrequency ablation as first-line treatment for small hepatocellular carcinoma: Results and prognostic factors on long-term follow up http://www.medworm.com/index.php?rid=3169055&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06125.x Conclusion: Percutaneous RFA under the protocol reported here has the potential to provide local tumor control for small HCC. In addition to host factors, time interval from RFA to recurrence was an important determinant of prognosis. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3169055 Thu, 14 Jan 2010 00:00:00 +0100 3169055 Radiotherapy for hepatocellular carcinoma: Systematic review of radiobiology and modeling projections indicate reconsideration of its use http://www.medworm.com/index.php?rid=3169054&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06126.x Conclusion: New radiobiological data, modeling, emerging clinical data and the advantages offered by standard external beam radiotherapy techniques suggest the need for reconsidering the use of radiotherapy and for new trials. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3169054 Thu, 14 Jan 2010 00:00:00 +0100 3169054 Hepatitis C virus induces oxidative stress, DNA damage and modulates the DNA repair enzyme NEIL1 http://www.medworm.com/index.php?rid=3169053&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06128.x Conclusion: Collectively, the data indicate that HCV induction of ROS and perturbation of NEIL1 expression may be mechanistically involved in progression of liver disease and suggest that antioxidant and antiviral therapies can reverse these deleterious effects of HCV in part by restoring function of the DNA repair enzyme/s. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3169053 Thu, 14 Jan 2010 00:00:00 +0100 3169053 Trend of colorectal cancer in Hong Kong: 1983–2006 http://www.medworm.com/index.php?rid=3169052&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06130.x Conclusions: Increasing incidence of CC in HK was mostly in the older and male population, but not in the younger age group. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3169052 Thu, 14 Jan 2010 00:00:00 +0100 3169052 Terlipressin therapy for reversal of type 1 hepatorenal syndrome: A meta-analysis of randomized controlled trials http://www.medworm.com/index.php?rid=3169051&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06132.x Background and Aim: Hepatorenal syndrome (HRS) is a serious complication of advanced liver disease and carries a poor prognosis. Recent trials have indicated that terlipressin may be effective in reversing HRS. Our aim was to evaluate the efficacy of terlipressin therapy in reversing type 1 HRS defined as a serum creatinine (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3169051 Thu, 14 Jan 2010 00:00:00 +0100 3169051 Bugs and irritable bowel syndrome: The good, the bad and the ugly http://www.medworm.com/index.php?rid=3169050&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06133.x Recently, there has been strong interest in the therapeutic potential of probiotics for irritable bowel syndrome (IBS). At the same time, there is a rapidly growing body of evidence to support an etiological role for gastrointestinal infection and the associated immune activation in the development of post-infectious IBS. In a more controversial area, small intestinal bacterial overgrowth has been associated with a subset of patients with IBS; the issue of whether it is appropriate to treat a subset of IBS patients with antibiotics and probiotics is currently a matter for debate. Thus, it appears that the gastrointestinal microbial flora may exert beneficial effects for symptoms of IBS under some circumstances, while in other situations gut microbes could give rise to symptoms of IBS. How ... Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3169050 Thu, 14 Jan 2010 00:00:00 +0100 3169050 Prevalence of Helicobacter pylori infection in duodenal ulcer and gastro-duodenal ulcer diseases in Taiwan http://www.medworm.com/index.php?rid=3169049&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06139.x Conclusion: The prevalence of H. pylori infection in DU appears to be decreasing in Taiwan. Thus, eradication therapy without confirming the presence of H. pylori in DU patients cannot be recommended. NSAIDs/aspirin is the major risk factor for H. pylori-negative DU patients, especially those with co-morbid gastric ulcer. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3169049 Thu, 14 Jan 2010 00:00:00 +0100 3169049 Population-based cases control study of inflammatory bowel disease risk factors http://www.medworm.com/index.php?rid=3169048&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06140.x Conclusions: The importance of childhood factors in the development of IBD is confirmed. The duration-response protective association between breast-feeding and subsequent development of IBD requires further evaluation, as does the protective effect associated with a childhood vegetable garden. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3169048 Thu, 14 Jan 2010 00:00:00 +0100 3169048 Intra-arterial 5-fluorouracil/interferon combination therapy for hepatocellular carcinoma with portal vein tumor thrombosis and extrahepatic metastases http://www.medworm.com/index.php?rid=3169047&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06110.x Conclusions: The efficacy of 5-FU/IFN for advanced HCC with Vp3/4 and extrahepatic metastases was markedly limited. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3169047 Thu, 14 Jan 2010 00:00:00 +0100 3169047 Accuracy of high-frequency catheter-based endoscopic ultrasonography according to the indications for endoscopic treatment of early gastric cancer http://www.medworm.com/index.php?rid=3169046&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06111.x Conclusions: The accuracy of EUS for the lesions with the extended indications was lower than that for the lesions with the accepted indications. In particular, lesions with ulceration and minute submucosal invasion should be carefully considered prior to endoscopic treatment by pretreatment EUS staging. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3169046 Thu, 14 Jan 2010 00:00:00 +0100 3169046 Diagnostic accuracy of multidetector-row computed tomography for hilar cholangiocarcinoma http://www.medworm.com/index.php?rid=3169045&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06113.x Conclusions: The diagnostic accuracy of MDCT for tumor location and vertical invasion was satisfactory, but ductal spread was underestimated in comparison with microscopic measurements. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3169045 Thu, 14 Jan 2010 00:00:00 +0100 3169045 Investigation of doublecortin and calcium/calmodulin-dependent protein kinase-like-1-expressing cells in the mouse stomach http://www.medworm.com/index.php?rid=3169044&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06114.x Conclusion: Using DCAMKL-1 as a marker for stomach stem cells, we could describe the expression pattern of stomach stem cells during mucosal injury. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3169044 Thu, 14 Jan 2010 00:00:00 +0100 3169044 Favorable α-fetoprotein decrease as a prognostic surrogate in patients with hepatocellular carcinoma after radiofrequency ablation http://www.medworm.com/index.php?rid=3169043&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06115.x Conclusions: A favorable [alpha]-fetoprotein decrease has better predictive power for disease-free survival than for an unfavorable [alpha]-fetoprotein decrease. HCC patients after RFA with an unfavorable [alpha]-fetoprotein decrease should be considered to have undergone incomplete treatment, despite the complete response by standard image modality post-RFA. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3169043 Thu, 14 Jan 2010 00:00:00 +0100 3169043 Characteristics of delayed hemorrhage after endoscopic sphincterotomy http://www.medworm.com/index.php?rid=3169042&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06123.x Conclusion: Complete control of intra-procedural bleeding is an important step in the prevention of late post-EST hemorrhage. Careful observation for delayed hemorrhage after EST, especially in patients with CKD, hypertension and IHD, is recommended. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3169042 Thu, 14 Jan 2010 00:00:00 +0100 3169042 Treatment of type I gastric neuroendocrine tumors with somatostatin analogs http://www.medworm.com/index.php?rid=3169041&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06131.x Conclusions: Octreotide-LAR therapy causes regression of type-I gastric neuroendocrine tumors. After completion of drug therapy there was no recurrence of tumors even with continued hypergastrinemia. Octreotide therapy should be considered as one of the treatment options in such patients. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3169041 Thu, 14 Jan 2010 00:00:00 +0100 3169041 Effect of biotherapeutics on cyclosporin-induced Clostridium difficile infection in mice http://www.medworm.com/index.php?rid=3169040&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06135.x Conclusions: Cyclosporin led to the development of mild to moderate CDAD in animals. Administration of biotherapeutics reduced the severity of CDAD. Future clinical trials are needed for further investigation of these potential biotherapeutic measures. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3169040 Thu, 14 Jan 2010 00:00:00 +0100 3169040 Prevalence of erosive esophagitis among Japanese patients taking low-dose aspirin http://www.medworm.com/index.php?rid=3169062&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06105.x Conclusion: In Japanese patients taking ASA, EE was not as common as peptic ulcers. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3169062 Wed, 13 Jan 2010 00:00:00 +0100 3169062 Comparison of temporary stent insertion with pneumatic dilation of the same diameter in the treatment of achalasia patients: A retrospective study http://www.medworm.com/index.php?rid=3169061&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06107.x Conclusion: Retrievable stent placement is more effective than the same diameter pneumatic dilation for the treatment of achalasia with a long-term follow up. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3169061 Wed, 13 Jan 2010 00:00:00 +0100 3169061 Successful stenting in ductal disruption favorably impacts treatment outcomes in patients undergoing transmural drainage of peripancreatic fluid collections http://www.medworm.com/index.php?rid=3169060&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06109.x Conclusions: Transpapillary PD stenting improves treatment outcomes in patients undergoing endoscopic transmural drainage of PFC. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3169060 Wed, 13 Jan 2010 00:00:00 +0100 3169060 Polymorphisms in promoter region of FAS and FASL gene and risk of gastric cardiac adenocarcinoma http://www.medworm.com/index.php?rid=3169059&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06116.x Conclusion: In the high-incidence region of Hebei Province, FAS-1377 G/A and FASL-844 T/C polymorphisms were not associated with the risk of GCA. However, the FAS-670 A/G genotype might decrease the risk of GCA for smoker individuals. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3169059 Wed, 13 Jan 2010 00:00:00 +0100 3169059 Relationship of non-alcoholic fatty liver disease to colorectal adenomatous polyps http://www.medworm.com/index.php?rid=3169058&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06117.x Conclusion: NAFLD was associated with colorectal adenomatous polyps. Further studies are needed to confirm whether NAFLD is a predictor for the development of colorectal adenomatous polyps and cancer. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3169058 Wed, 13 Jan 2010 00:00:00 +0100 3169058 Prevalence and clinical characterization of patients with acute hepatitis B induced by lamivudine-resistant strains http://www.medworm.com/index.php?rid=3169057&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06118.x Conclusion: LMV-resistant strains are rare, but they are starting to be found in patients with acute hepatitis B. Surveillance for detecting drug-resistant HBV strains would be important for clinical practice. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3169057 Wed, 13 Jan 2010 00:00:00 +0100 3169057 Irritable bowel syndrome: Epidemiology, diagnosis and treatment: An update for health-care practitioners http://www.medworm.com/index.php?rid=3169056&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06120.x Irritable bowel syndrome (IBS), a chronic gastrointestinal disorder, affects from 3[ndash]20% of the US population, depending on sociocultural and comorbid factors. IBS is characterized by a symptom complex of abdominal pain and abnormal bowel habits that present as diarrhea or constipation, and general physical weakness in the absence of abnormal morphological, histological or inflammatory markers. The main diagnostic Rome III criteria as established by international professional organizations are based on exclusion criteria and the occurrence and rate of symptoms. Because the pathophysiology and causes of IBS are poorly understood, treatment approaches are mainly focused on symptom management to maintain everyday functioning and improve quality of life for persons with IBS. The mainstay ... Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3169056 Wed, 13 Jan 2010 00:00:00 +0100 3169056 Anandamide induces cell death through lipid rafts in hepatic stellate cells http://www.medworm.com/index.php?rid=3140172&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06122.x Conclusion: These results demonstrated that AEA induced HSC necrosis through lipid rafts: a possible role of PI3K/PKB signaling pathway downregulation and inflammatory factors production. Cholesterol depletion abolished the effects of AEA on HSC necrosis. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3140172 Tue, 05 Jan 2010 00:00:00 +0100 3140172 Bmi-1 is critical for the proliferation and invasiveness of gastric carcinoma cells http://www.medworm.com/index.php?rid=3041363&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06045.x Conclusions: Our study highlights critical roles for Bmi-1 in gastric cancer, and suggests that Bmi-1 nuclear localization could be an important marker for the diagnosis of gastric cancer. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3041363 Tue, 01 Dec 2009 00:00:00 +0100 3041363 Histological evaluation of intracapsular venous invasion for discrimination between portal and hepatic venous invasion in hepatocellular carcinoma http://www.medworm.com/index.php?rid=3020393&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06008.x Conclusions: D2-40 immunoreactivity for the histological evaluation of IVI in HCC allows discrimination between portal and hepatic venous invasion for cases in which portal venous invasion predominates. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3020393 Tue, 24 Nov 2009 00:00:00 +0100 3020393 Roles of Fyn in pancreatic cancer metastasis http://www.medworm.com/index.php?rid=3020392&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06021.x Conclusions: Our results suggest a possible mechanism by which Fyn activity regulates cell proliferation and apoptosis that exerts an effect on pancreatic cancer metastasis. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3020392 Tue, 24 Nov 2009 00:00:00 +0100 3020392 Does a small biopsied gastric specimen limit the usage of two directional transnasal esophagogastroduodenoscopy? http://www.medworm.com/index.php?rid=3020391&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06029.x Conclusion: TN-EGD biopsied specimens obtained from the posterior aspect of the cardia exhibit limitations in both quality and quantity. When performing a biopsy using two directional TN-EGD, special attention should be paid to gastric lesions located on the posterior aspect of the cardia. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3020391 Tue, 24 Nov 2009 00:00:00 +0100 3020391 Low-grade dysplasia component in early invasive squamous cell carcinoma of the esophagus http://www.medworm.com/index.php?rid=3020390&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06032.x Conclusion: Our results indicate the possibility that the lesion was formed by a combination of small lesions that arose as a multicentric occurrence of squamous cell carcinoma and dysplasia. Our results also suggest that an LGD component would transform to carcinoma along with tumor progression. However, the concept of 'basal cell layer type carcinoma in situ' may be suitable for squamous cell lesions with a high degree of cytological abnormalities confined to the lower half of the epithelium. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3020390 Tue, 24 Nov 2009 00:00:00 +0100 3020390 Electrogastrographic characteristics in subjects with stomach remnant http://www.medworm.com/index.php?rid=3020389&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06038.x Conclusions: Distal RSG patients may have decreased SW frequency and less meal ingestion changed EGG parameters in terms of SW frequency, normality and stability, whereas their EGG power remained unchanged irrespective of meal ingestion. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3020389 Tue, 24 Nov 2009 00:00:00 +0100 3020389 Four hundred and twenty-three consecutive adults piggy-back liver transplantations with the three suprahepatic veins: Was the portal systemic shunt required? http://www.medworm.com/index.php?rid=3020388&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06084.x Conclusion: This experience indicates that our approach is feasible with a low specific risk and can be performed without portacaval shunt, with minimal outflow venous complications. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3020388 Tue, 24 Nov 2009 00:00:00 +0100 3020388 Influential factors of prognosis in lamivudine treatment for patients with acute-on-chronic hepatitis B liver failure http://www.medworm.com/index.php?rid=3020387&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06089.x Conclusion: Lamivudine can significantly decrease the 3-month mortality of patients with a MELD score of 20[ndash]30, and a low pretreatment viral load and rapid decline of HBV DNA load are good predictors for the outcome of the treatment. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3020387 Tue, 24 Nov 2009 00:00:00 +0100 3020387 Do we need an 'in-house' neutralization assay for confirmation of hepatitis B surface antigen? Answers from a tertiary care hospital in India http://www.medworm.com/index.php?rid=3010060&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06088.x Conclusion: The enzyme immunoassay-based 'in-house' HBsAg neutralization assay is a feasible alternative to the commercial HBsAg confirmatory assay. This technique is easily adaptable, cost-effective and reliable for the confirmation of HBsAg in a low resource setting, enhancing the overall quality of HBsAg screening. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3010060 Fri, 20 Nov 2009 00:00:00 +0100 3010060 Evidence for the insufficient evaluation and undertreatment of chronic hepatitis B infection in a predominantly low-income and immigrant population http://www.medworm.com/index.php?rid=3010071&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06023.x Conclusions: After the diagnosis of HBV infection, few patients in our population received laboratory evaluation to determine eligibility for HBV treatment. Furthermore, only a small percentage received HBV treatment. Further research needs to be done to validate these findings in other populations and understand barriers to receiving HBV treatment. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3010071 Thu, 19 Nov 2009 00:00:00 +0100 3010071 Radiofrequency ablation therapy for hepatocellular carcinoma in elderly patients http://www.medworm.com/index.php?rid=3010070&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06037.x Conclusions: Elderly HCC patients, who have good performance status, should be treated in the same manner and with the same strategy as young HCC patients. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3010070 Thu, 19 Nov 2009 00:00:00 +0100 3010070 Naturally occurring K vitamins inhibit pancreatic cancer cell survival through a caspase-dependent pathway http://www.medworm.com/index.php?rid=3010069&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06085.x Conclusion: These data show that naturally-occurring, non-toxic K vitamins can inhibit the survival of some pancreatic cancer cell lines. These novel, safe and clinically-utilized agents initiate a caspase-dependent apoptosis via the MAP kinase pathway and could potentially benefit patients with pancreatic cancer either as a single agent or in combination with chemotherapy for treatment, or for prevention of recurrence of pancreas cancer post resection. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3010069 Thu, 19 Nov 2009 00:00:00 +0100 3010069 Gastric metastasis of hepatocellular carcinoma via a possible existing retrograde hematogenous pathway http://www.medworm.com/index.php?rid=3010068&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06022.x Conclusions: When cirrhotic patients with portal hypertension have HCC with PVT, a hematogenous pathway can exist for gastric metastasis of tumor thrombi involving hepatofugal flow to the stomach after TAE or EVL apart from the major pathway of direct invasion. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3010068 Thu, 19 Nov 2009 00:00:00 +0100 3010068 Asian perspectives in the management of inflammatory bowel disease: Findings from a recent survey http://www.medworm.com/index.php?rid=3010067&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06024.x Conclusion: Clinical practice with regards to IBD diagnosis and management varies within Asia.5-ASA is the preferred treatment and maintenance therapy for mild-to-moderate IBD. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3010067 Thu, 19 Nov 2009 00:00:00 +0100 3010067 Laparoscopic splenectomy may be a superior supportive intervention for cirrhotic patients with hypersplenism http://www.medworm.com/index.php?rid=3010066&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06031.x Conclusion: Laparoscopic splenectomy may be superior to partial splenic embolization as a supportive intervention for cirrhotic patients with hypersplenism. Future prospective, randomized controlled patient studies are required to confirm these findings. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3010066 Thu, 19 Nov 2009 00:00:00 +0100 3010066 Factors associated with nutritional status in liver transplant patients who survived the first year after transplantation http://www.medworm.com/index.php?rid=3010065&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06033.x Conclusion: No influence on nutritional status was observed for peri- or postoperative factors after 3 or 12 months of follow up. As expected, dietary factors, especially adequate calorie intake, were always associated with nutritional status during all periods analyzed. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3010065 Thu, 19 Nov 2009 00:00:00 +0100 3010065 Clinical manifestations and survival of patients with hepatocellular carcinoma and cardiac metastasis http://www.medworm.com/index.php?rid=3010064&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06036.x Conclusions: Hepatocellular carcinoma patients with cardiac metastases were in the advanced stages. These patients had limited survival from the diagnosis of cardiac metastases. The most common cause of death was related to HCC per se or the underlying liver disease. Only a few patients expired because of cardiac metastases. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3010064 Thu, 19 Nov 2009 00:00:00 +0100 3010064 Prevalence, human leukocyte antigen typing and strategy for screening among Asian first-degree relatives of children with celiac disease http://www.medworm.com/index.php?rid=3010063&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06044.x Conclusions: In this first Asian study on a limited number of families of children with CD, 4.4% of the first-degree relatives had CD. Only 15% of the first-degree relatives were negative for HLA DQ2/DQ8. Initial evaluation with HLA and serology followed by only serial serology in HLA-positive relatives is recommended. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3010063 Thu, 19 Nov 2009 00:00:00 +0100 3010063 TLR4 monoclonal antibody blockade suppresses dextran-sulfate-sodium-induced colitis in mice http://www.medworm.com/index.php?rid=3010062&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06046.x Conclusion: Blocking TLR4 by TLR4mAb can prevent the development of DSS-induced colitis through the TLR4-P38MAPK-c-jun pathway. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3010062 Thu, 19 Nov 2009 00:00:00 +0100 3010062 Endoplasmic reticulum stress involved in the course of lipogenesis in fatty acids-induced hepatic steatosis http://www.medworm.com/index.php?rid=3010061&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06086.x Conclusion: Endoplasmic reticulum stress might be involved in lipogenesis in fatty acids-induced hepatic steatosis. Therefore, endoplasmic reticulum stress might serve as a novel target in the pathogenesis and therapy of non- alcoholic fatty liver disease. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=3010061 Thu, 19 Nov 2009 00:00:00 +0100 3010061 Sex differences in epidemiological, clinical and pathological characteristics of colorectal cancer http://www.medworm.com/index.php?rid=2928753&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05992.x Sex significantly influences the clinical and pathological characteristics of colorectal cancer (CRC). These include differences in incidence and mortality rates, clinical presentations including age, emergency surgery for complications from CRC, screening participation rates, site, stage and treatment utilization, histopathology and survival. Environmental, behavioral and biological factors contribute to the differential risk. Recent advances in the molecular biology of CRC, specifically in microsatellite status, estrogen hormone and estrogen receptor [beta], have led to greater understanding of the effect of estrogen in colorectal carcinogenesis. Estrogen may preferentially protect against microsatellite unstable cancers through its effect on selected molecular targets; however, the exac... Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2928753 Tue, 27 Oct 2009 00:00:00 +0100 2928753 Narrow-band imaging endoscopy with magnification is useful for detecting metachronous superficial pharyngeal cancer in patients with esophageal squamous cell carcinoma http://www.medworm.com/index.php?rid=2928752&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05993.x Conclusion: NBI endoscopy with magnification is a promising technique for detecting superficial pharyngeal cancer at an early stage in patients previously treated for esophageal SCC. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2928752 Tue, 27 Oct 2009 00:00:00 +0100 2928752 Oral buffered esomeprazole is superior to i.v. pantoprazole for rapid rise of intragastric pH: A wireless pH metry analysis http://www.medworm.com/index.php?rid=2928751&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05994.x Conclusion: BE achieves and maintains a pH of more than 6 within minutes of administration. It was significantly superior to i.v. pantoprazole in equivalent dosing. This finding could have implications in the management of non-variceal bleed where a rapid and sustained pH of more than 6 is desirable. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2928751 Tue, 27 Oct 2009 00:00:00 +0100 2928751 Eukaryotic expression of extracellular ligand binding domains of murine Tie-2 and its anti-angiogenesis effect in SGC-7901 cell lines http://www.medworm.com/index.php?rid=2928750&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05997.x Conclusion: The protein of extracellular ligand binding domains of murine Tie-2 can be expressed at high level in the eukaryotic expression system, and the expressed protein may have the anti-angiogenesis effect. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2928750 Tue, 27 Oct 2009 00:00:00 +0100 2928750 Protecting effects of a large dose of dexamethasone on spleen injury of rats with severe acute pancreatitis http://www.medworm.com/index.php?rid=2928749&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05999.x Conclusion: Dexamethasone can protect spleen from injury during SAP mainly by reducing the content of inflammatory mediators in blood. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2928749 Tue, 27 Oct 2009 00:00:00 +0100 2928749 Role of endoscopic ultrasound-guided fine-needle aspiration with flow cytometry to diagnose lymphoma: A single center experience http://www.medworm.com/index.php?rid=2906404&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06005.x Conclusions: EUS[minus]FNA is sensitive and specific for the diagnosis of suspected lymphoma. Confirmatory or further testing should be performed when EUS[minus]FNA with or without FC is indeterminate and or non-diagnostic. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2906404 Mon, 19 Oct 2009 23:00:00 +0100 2906404 Ascitic fluid infection in patients with hepatitis B virus-related liver cirrhosis: Culture-negative neutrocytic ascites versus spontaneous bacterial peritonitis http://www.medworm.com/index.php?rid=2906405&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05970.x Conclusions: Although in-hospital mortality was higher in patients with SBP than CNNA, the clinical course of the two groups was similar after the first episode of AFI. Thus, liver transplantation should be considered, irrespective of culture positivity of ascitic fluid. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2906405 Sun, 18 Oct 2009 23:00:00 +0100 2906405 Overlap of primary biliary cirrhosis and autoimmune hepatitis: Characteristics, therapy, and long term outcomes http://www.medworm.com/index.php?rid=2877716&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06018.x Conclusions: PBC-AIH overlap is not a rare entity; it was observed in 11% of PBC patients in this study. Further studies will be required to investigate whether PBC-AIH overlap is distinct from the two individual diseases in terms of long-term outcomes and therapeutic implications. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2877716 Fri, 09 Oct 2009 23:00:00 +0100 2877716 Occult hepatitis B virus infection and lamivudine-resistant mutations in isolates from renal patients undergoing hemodialysis http://www.medworm.com/index.php?rid=2877728&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05972.x Conclusions: HBV isolates with the identified substitutions have the potential to spread silently by nosocomial transmission within the hemodialysis unit. These results have potential implications for the management of patients with occult HBV infection undergoing hemodialysis. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2877728 Thu, 08 Oct 2009 23:00:00 +0100 2877728 Eradication of Helicobacter pylori infection improved gastric mucosal atrophy and prevented progression of intestinal metaplasia, especially in the elderly population: A long-term prospective cohort study http://www.medworm.com/index.php?rid=2877727&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05995.x Conclusion: Eradication of H. pylori infection improved gastric atrophy and prevented the progression of intestinal metaplasia in the elderly population during the long-term follow-up periods. H. pylori eradication for the elderly population is effective. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2877727 Thu, 08 Oct 2009 23:00:00 +0100 2877727 Fatty liver predicts impaired fasting glucose and type 2 diabetes mellitus in Japanese undergoing a health checkup http://www.medworm.com/index.php?rid=2877726&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05998.x Conclusion: Fatty liver is an independent risk factor for impaired fasting glucose and type 2 diabetes mellitus, having a stronger impact in those Japanese with a lower body mass index undergoing a health checkup. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2877726 Thu, 08 Oct 2009 23:00:00 +0100 2877726 Association of polymorphisms of glutamate-cystein ligase and microsomal triglyceride transfer protein genes in non-alcoholic fatty liver disease http://www.medworm.com/index.php?rid=2877725&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06001.x Conclusion: This difference clearly warrants further investigation in larger samples. These two polymorphisms could represent an additional factor for consideration in evaluating the risk of NAFLD progression. Further studies involving a larger population are necessary to confirm this notion. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2877725 Thu, 08 Oct 2009 23:00:00 +0100 2877725 Diagnosis of hepatic hydrothorax using contrast-enhanced ultrasonography with intraperitoneal injection of Sonazoid http://www.medworm.com/index.php?rid=2877724&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06002.x Conclusions: This is the first report to confirm transdiaphragmatic movement of ascitic fluid into the pleural cavity using contrast-enhanced ultrasonography with Sonazoid. This method can safely detect ascitic flow in real time, and is thus very useful for the diagnosis of hepatic hydrothorax. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2877724 Thu, 08 Oct 2009 23:00:00 +0100 2877724 High incidence of zinc deficiency among Filipino children with compensated and decompensated liver disease http://www.medworm.com/index.php?rid=2877723&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06003.x Conclusions: Children with chronic liver disease, whether in a compensated or decompensated state, had lower serum zinc levels compared with the healthy controls. As the severity of liver disease worsened, the zinc levels decreased. The study suggests that zinc supplementation should constitute part of the micronutrient intake of children with chronic liver disease. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2877723 Thu, 08 Oct 2009 23:00:00 +0100 2877723 Therapeutic effects of pegylated interferon plus ribavirin in chronic hepatitis C patients with occult hepatitis B virus dual infection http://www.medworm.com/index.php?rid=2877722&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06006.x Conclusion: Occult HBV infection in CHC patients is rare. The biochemical and virological responses to combined PEG[ndash]IFN and RBV therapy might be similar in CHC patients with or without occult HBV infection. The serum HBV[ndash]DNA level was low in patients with occult HBV/HCV dual infection who responded to combined therapy. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2877722 Thu, 08 Oct 2009 23:00:00 +0100 2877722 Ursodeoxycholic acid and artesunate in the treatment of severe falciparum malaria patients with jaundice http://www.medworm.com/index.php?rid=2877721&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06007.x Conclusions: In severe PF malaria patients with jaundice, combined therapy with UDCA and artesunate is safe, but does not significantly improve liver tests compared to placebo and artesunate. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2877721 Thu, 08 Oct 2009 23:00:00 +0100 2877721 Secreted protein acidic and rich in cysteine (SPARC) gene polymorphism association with hepatocellular carcinoma in Italian patients http://www.medworm.com/index.php?rid=2877720&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06009.x Conclusion: Since the presence of the rs2304052 C allele is associated with an increased risk (odds ratio: 2.76) of developing hepatocarcinoma, our results allowed us to identify a SNP in the SPARC gene correlating to HCC susceptibility. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2877720 Thu, 08 Oct 2009 23:00:00 +0100 2877720 Simple diagnostic approach to childhood fecal retention using the Leech score and Bristol stool form scale in medical practice http://www.medworm.com/index.php?rid=2877719&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06015.x Conclusions: The Leech score and the Bristol stool form scale may be simple and useful diagnostic tools for pediatricians to access childhood fecal loading in outpatient clinics along with a thorough clinical history. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2877719 Thu, 08 Oct 2009 23:00:00 +0100 2877719 Diagnosis of obscure gastrointestinal hemorrhage with capsule endoscopy in combination with multiple-detector computed tomography http://www.medworm.com/index.php?rid=2877718&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06016.x Conclusion: The contribution of CE is critical in the diagnosis of GHOO, given the fact that there is a significant difference in the detection rate between CE and MDCT, but there is no significant difference in the rate between CE plus MDCT and CE alone. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2877718 Thu, 08 Oct 2009 23:00:00 +0100 2877718 Cow's milk protein allergy: An entity for recognition in developing countries http://www.medworm.com/index.php?rid=2877717&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06017.x Conclusions: CMPA is not uncommon in a developing country such as India. Presence of aphthous ulcers and abnormal rectal biopsy are clues to initial diagnosis. Milk challenge confirms the diagnosis in all if it is done on time. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2877717 Thu, 08 Oct 2009 23:00:00 +0100 2877717 Monitoring of CD95 and CD38 expression in peripheral blood T lymphocytes during active human cytomegalovirus infection after orthotopic liver transplantation http://www.medworm.com/index.php?rid=2873572&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05966.x Conclusions: The present study showed that CD38+CD8+ T cells can be an appropriate immunological marker for early detection and antiviral therapeutic monitoring of HCMV infection. The evaluation of CD95 molecule levels may be used routinely in clinical practice to assess the level of immunosuppression. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2873572 Thu, 08 Oct 2009 23:00:00 +0100 2873572 Prevalence of gastroesophageal reflux disease in patients with asthma and chronic obstructive pulmonary disease http://www.medworm.com/index.php?rid=2873573&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.06035.x Conclusions: These results implicate that the prevalence of GERD in asthma and COPD are lower than in published reports in a tertiary referral center. These differences might be related to the characteristics of developing countries, increased consumption of powerful medications in GERD and pulmonary diseases, or methodological flaws in earlier studies. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2873573 Wed, 07 Oct 2009 23:00:00 +0100 2873573 Outcomes of endoscopic resection of large colorectal neoplasms: An Australian experience http://www.medworm.com/index.php?rid=2837217&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05987.x Conclusion: Endoscopic resection of large colorectal neoplasms is safe and effective even for very large benign neoplasms. When the lesion is endoscopically resectable this should be the preferred treatment. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2837217 Sun, 27 Sep 2009 23:00:00 +0100 2837217 Association of exon 9 but not intron 8 VDR polymorphisms with occult HBV infection in south-eastern Iranian patients http://www.medworm.com/index.php?rid=2837228&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05950.x Conclusion: The polymorphisms in the T/T allele of exon 9 of VDR is possibly associated with OBI, thus it can be concluded that VDR and its functional polymorphisms are likely to be related to sensitivity and resistance of the immune system to HBV in OBI patients. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2837228 Sat, 26 Sep 2009 23:00:00 +0100 2837228 Usefulness of non-invasive markers for predicting liver cirrhosis in patients with chronic hepatitis B http://www.medworm.com/index.php?rid=2837227&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05953.x Conclusion: The devised PAHA system was found to be useful for predicting the presence of liver cirrhosis in patients with chronic hepatitis B. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2837227 Sat, 26 Sep 2009 23:00:00 +0100 2837227 Chronic pancreatitis in Chinese children: Etiology, clinical presentation and imaging diagnosis http://www.medworm.com/index.php?rid=2837226&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05967.x Conclusion: The main etiological factor of Chinese children with CP is idiopathic. The main symptom in these patients is multiple episodes of mild to moderate abdominal pain, which often lead to a delay in the definite diagnosis. CT and MRCP (or MRI) should be used as the first investigation in the evaluation of these cases. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2837226 Sat, 26 Sep 2009 23:00:00 +0100 2837226 Usefulness of polyethylene glycol solution with dimethylpolysiloxanes for bowel preparation before capsule endoscopy http://www.medworm.com/index.php?rid=2837225&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05968.x Conclusion: Bowel preparation using 1 L PEG with dimethylpolysiloxane 3 h before CE significantly reduced residue and intraluminal gas bubbles, and was considered to be a useful method for CE. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2837225 Sat, 26 Sep 2009 23:00:00 +0100 2837225 MicroRNA-224 is upregulated in HepG2 cells and involved in cellular migration and invasion http://www.medworm.com/index.php?rid=2837224&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05971.x Conclusions: Overexpression of miR-224 was involved in the malignant phenotype of HepG2 cells, and it may be an important factor in regulating the migration and invasion of HepG2 cells. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2837224 Sat, 26 Sep 2009 23:00:00 +0100 2837224 Analysis of 3'-end variable region of the cagA gene in Helicobacter pylori isolated from Iranian population http://www.medworm.com/index.php?rid=2837223&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05979.x Conclusion: The structure of the 3' region of the cagA gene in Iranian strains was Western type. Although we could not find differences between EPIYA types and clinical outcomes, low prevalence of strains with multiple EPIYA-C segments might be reasons for low incidence of gastric cancer in Iran. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2837223 Sat, 26 Sep 2009 23:00:00 +0100 2837223 Interstitial cells of Cajal are present in human extrahepatic bile ducts http://www.medworm.com/index.php?rid=2837222&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05980.x Conclusion: This study demonstrates for the first time that ICC are present in human extrahepatic bile ducts where they are more densely aggregated than in the gallbladder. This cellular network is likely to be involved in biliary tract motility and its related disorders. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2837222 Sat, 26 Sep 2009 23:00:00 +0100 2837222 Compound Astragalus and Salvia miltiorrhiza extract inhibits cell invasion by modulating transforming growth factor-β/Smad in HepG2 cell http://www.medworm.com/index.php?rid=2837221&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05981.x Conclusion: All these results suggest that CASE exerts anti-HepG2 cell invasion effect by modulating TGF-[beta]/Smad signaling. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2837221 Sat, 26 Sep 2009 23:00:00 +0100 2837221 Diagnostic role of serum glypican-3 in differentiating hepatocellular carcinoma from non-malignant chronic liver disease and other liver cancers http://www.medworm.com/index.php?rid=2837220&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05988.x Conclusion: Serum GPC3 is highly specific for detecting HCC. The combined use of serum GPC3 and AFP provides a potentially promising tool to better differentiate HCC from benign liver disorders, as well as from other liver cancers. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2837220 Sat, 26 Sep 2009 23:00:00 +0100 2837220 Serum ornithine carbamyltransferase reflects hepatic damage in diabetic obese mice http://www.medworm.com/index.php?rid=2837219&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05969.x Conclusions: Serum OCT seemed to reflect tumor necrosis factor-alpha-mediated hepatic damage when compared with ALT in diabetic obese mice and could be useful in the application for non-alcoholic fatty liver disease with features of metabolic syndrome, such as obesity and diabetes. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2837219 Sat, 26 Sep 2009 23:00:00 +0100 2837219 Short-term celecoxib to regress long-term persistent gastric intestinal metaplasia after Helicobacter pylori eradication http://www.medworm.com/index.php?rid=2837218&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05974.x Conclusion: Short-term celecoxib treatment can be safe and promising to regress long-term persistent IM after H. pylori eradication. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2837218 Sat, 26 Sep 2009 23:00:00 +0100 2837218 Hydroxyoctadecadienoic acid as a potential biomarker for oxidative stress in patients with chronic hepatitis C http://www.medworm.com/index.php?rid=2829809&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05928.x Conclusion: The levels of tHODE in chronic HCV-infected patients can be a useful biomarker for the evaluation of oxidative stress in chronic hepatitis C. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2829809 Thu, 24 Sep 2009 23:00:00 +0100 2829809 Evaluation of visualization of squamous cell carcinoma of esophagus and pharynx using an autofluorescence imaging videoendoscope system http://www.medworm.com/index.php?rid=2829808&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05941.x Conclusion: The AFI system appears to be more useful than WLE for early diagnosis of SCC of the esophagus and pharynx. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2829808 Thu, 24 Sep 2009 23:00:00 +0100 2829808 Prevalence of irritable bowel syndrome and its relationship with psychological stress status in Chinese university students http://www.medworm.com/index.php?rid=2829807&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05943.x Conclusion: The prevalence of IBS in Chinese university students is often compared with university students in developed countries and the general Chinese population. Depression and anxiety could potentially induce IBS. Medical education should be considered when aiming to reduce stress of university students who are susceptible to IBS. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2829807 Thu, 24 Sep 2009 23:00:00 +0100 2829807 Intraductal ultrasonography combined with percutaneous transhepatic cholangioscopy for the preoperative evaluation of longitudinal tumor extent in hilar cholangiocarcinoma http://www.medworm.com/index.php?rid=2829806&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05944.x Conclusions: The combination of IDUS and PTCS with biopsy was highly accurate for assessing Bismuth type and may help in the identification of an optimal surgical plan for the treatment of hilar cholangiocarcinoma, especially in Bismuth type IIIa, IIIb, or IV. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2829806 Thu, 24 Sep 2009 23:00:00 +0100 2829806 Feasibility of individualized treatment for hepatitis C patients in the real world http://www.medworm.com/index.php?rid=2829805&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05946.x Conclusion: Individualized therapy is feasible in the real world, especially for patients with HCV-1 infection. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2829805 Thu, 24 Sep 2009 23:00:00 +0100 2829805 Guidewire cannulation increases the success rate of needle-knife fistulotomy for difficult bile duct access http://www.medworm.com/index.php?rid=2829804&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05947.x Conclusions: In this retrospective and small case series, guidewire cannulation after needle-knife fistulotomy increased the success rate of selective bile duct cannulation in patients with difficult bile duct access. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2829804 Thu, 24 Sep 2009 23:00:00 +0100 2829804 N-Acetylcysteine improves disturbed ileal contractility following partial hepatectomy in rats http://www.medworm.com/index.php?rid=2829803&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05948.x Conclusions: Our data indicated that disturbed ileal contractility after partial hepatectomy was remedied by preoperative NAC treatment, which in turn might cause attenuation of bacterial translocation. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2829803 Thu, 24 Sep 2009 23:00:00 +0100 2829803 Effect of miRNA-10b in regulating cellular steatosis level by targeting PPAR-α expression, a novel mechanism for the pathogenesis of NAFLD http://www.medworm.com/index.php?rid=2829802&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05949.x Conclusion: The established miRNA profile of the steatotic L02 cell model and the novel effect of miRNA-10b in regulating hepatocyte steatosis may provide a new explanation of the pathogenesis of NAFLD. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2829802 Thu, 24 Sep 2009 23:00:00 +0100 2829802 Pilot study on confocal endomicroscopy for determination of the depth of squamous cell esophageal cancer in vivo http://www.medworm.com/index.php?rid=2829801&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05892.x Conclusion: Scoring and quantification of confocal endomicroscopic images may be useful for the differential diagnosis and diagnosis of superficial invasion by squamous cell carcinoma. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2829801 Thu, 24 Sep 2009 23:00:00 +0100 2829801 Effect of baicalin and octreotide on the expression levels of P-selectin protein in multiple organs of rats with severe acute pancreatitis http://www.medworm.com/index.php?rid=2829800&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05902.x Conclusion: Both baicalin and octreotide can exert some protective effects on multiple organs and the former is superior to the latter in protecting pancreas. Furthermore, decreasing the expression levels of P-selectin protein in these organs is one of the possible mechanisms. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2829800 Thu, 24 Sep 2009 23:00:00 +0100 2829800 Biliary drainage, photodynamic therapy and chemotherapy for unresectable cholangiocarcinoma with jaundice http://www.medworm.com/index.php?rid=2829799&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05915.x Conclusion: These results confirm the beneficial effect of biliary drainage, photodynamic therapy and chemotherapy for unresectable cholangiocarcinoma in selected patients with jaundice. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2829799 Thu, 24 Sep 2009 23:00:00 +0100 2829799 Protective effects of resveratrol on small intestines against intestinal ischemia–reperfusion injury in rats http://www.medworm.com/index.php?rid=2829798&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05945.x Conclusions: The results of this study indicated that resveratrol treatment limits the oxidative injury of the small intestine induced by I/R in rats. However, more precise investigations are required to evaluate the antioxidative effect of resveratrol on small intestine tissue damage in clinical and experimental models. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2829798 Thu, 24 Sep 2009 23:00:00 +0100 2829798 Adefovir plus lamivudine are more effective than adefovir alone in lamivudine-resistant HBeAg- chronic hepatitis B patients: A 4-year study http://www.medworm.com/index.php?rid=2822037&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05952.x Background and Aim: Adefovir dipivoxil (ADV) is effective in lamivudine (LAM)-resistant hepatitis B e antigen-negative (HBeAg-) chronic hepatitis B (CHB). However, it is unclear whether LAM treatment should be continued in these patients. We aimed to compare the long-term efficacy of adding ADV to ongoing LAM treatment versus switching to ADV monotherapy in LAM-resistant HBeAg- CHB.Methods: Sixty LAM-resistant patients with HBeAg- CHB were randomly assigned (3:1) to combination therapy (10 mg ADV once daily plus ongoing LAM at 100 mg once daily [n = 45]) or 10 mg ADV monotherapy once daily (n = 15). Virological and biochemical responses were defined as hepatitis B virus (HBV)[ndash]DNA (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2822037 Tue, 22 Sep 2009 23:00:00 +0100 2822037 Cecal intubation rate with the double-balloon endoscope after incomplete conventional colonoscopy: A study in 45 patients http://www.medworm.com/index.php?rid=2665274&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05942.x Conclusions: The present study illustrates that the concept of double-balloon endoscopy is a valuable alternative to reach the cecum after prior incomplete conventional colonoscopy, especially due to redundant colon and colonic loop formation. The procedure requires less conscious sedation and no fluoroscopic control, but allows all conventional endoscopic interventions. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2665274 Mon, 03 Aug 2009 23:00:00 +0100 2665274 Effects of terlipressin on systemic, hepatic and renal hemodynamics in patients with cirrhosis http://www.medworm.com/index.php?rid=2665289&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05873.x Conclusion: Terlipressin decreases hepatic and renal arterial resistance in patients with cirrhosis. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2665289 Sun, 02 Aug 2009 23:00:00 +0100 2665289 Interleukin-27 polymorphisms are associated with inflammatory bowel diseases in a Korean population http://www.medworm.com/index.php?rid=2665288&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05901.x Conclusion: Our results suggest that the g.-964A > G polymorphism of the IL-27 gene located on the IBD1 locus might be associated with the susceptibility to IBD. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2665288 Sun, 02 Aug 2009 23:00:00 +0100 2665288 Melatonin prevents peritoneal adhesions in rats http://www.medworm.com/index.php?rid=2665287&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05907.x Conclusion: Antioxidant activity increases in the oxidative process. We conclude that melatonin may be an important molecule in preventing peritoneal adhesions. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2665287 Sun, 02 Aug 2009 23:00:00 +0100 2665287 Propranolol reduces variceal pressure and wall tension in schistosomiasis presinusoidal portal hypertension http://www.medworm.com/index.php?rid=2665286&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05912.x Conclusion: Propranolol significantly reduced variceal pressure and wall tension in schistosomiasis. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2665286 Sun, 02 Aug 2009 23:00:00 +0100 2665286 Validation of model for end-stage liver disease score to serum sodium ratio index as a prognostic predictor in patients with cirrhosis http://www.medworm.com/index.php?rid=2665285&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05913.x Conclusions: The MESO index, which adds SNa to MELD, is a useful prognostic marker and is found to be superior to the MELD score and modified CTP score for short-term prognostication of patients with cirrhosis. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2665285 Sun, 02 Aug 2009 23:00:00 +0100 2665285 Non-alcoholic fatty liver disease: An expanding problem with low levels of awareness in Hong Kong http://www.medworm.com/index.php?rid=2665284&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05914.x Conclusion: This survey revealed an inadequate knowledge of NAFLD among the general population in Hong Kong. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2665284 Sun, 02 Aug 2009 23:00:00 +0100 2665284 Protein C and D-dimer are related to portal vein thrombosis in patients with liver cirrhosis http://www.medworm.com/index.php?rid=2665283&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05921.x Conclusions: Cirrhotic patients displayed dysfunctions in the coagulation, anti-coagulation and fibrolytic systems. The development of PVT in these patients may be independently associated with the decrease of PC, PS and D-dimer. Furthermore, decreasing PC and increasing D-dimer may be risk factors inducing PVT in cirrhotic patients. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2665283 Sun, 02 Aug 2009 23:00:00 +0100 2665283 Quantitation of tissue polypeptide antigen (TPA) in hepatic and systemic circulation in patients with chronic liver diseases http://www.medworm.com/index.php?rid=2665282&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05916.x Conclusions: Our data suggest that the increased TPA levels observed in cirrhotic patients and the high systemic-to-hepatic blood TPA gradient are probably due to the presence of portal-systemic shunts rather than to hepatic necro-inflammatory activity. In clinical practice, TPA determination could help us to identify and to follow up cirrhotic patients with more severe portal hypertension. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2665282 Sun, 02 Aug 2009 23:00:00 +0100 2665282 Preoperative colonoscopy for patients with gastric adenocarcinoma http://www.medworm.com/index.php?rid=2665281&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05922.x Conclusion: Preoperative colonoscopy for screening of CRN should be considered in GA patients [ge] 50 years because of a relatively high prevalence of CRN and the possibility of synchronous CRC. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2665281 Sun, 02 Aug 2009 23:00:00 +0100 2665281 Impact of the Tokyo guidelines on the management of patients with acute calculous cholecystitis http://www.medworm.com/index.php?rid=2665280&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05923.x Conclusion: No significant benefit of the application of the Tokyo guidelines in the management of patients was found between the two subgroups except for reduced mean length of hospital stay. The application of the Tokyo guidelines for improving the outcomes of patients with acute cholecystitis needs further investigation and evaluation. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2665280 Sun, 02 Aug 2009 23:00:00 +0100 2665280 Epidemiology of hepatitis E: Current status http://www.medworm.com/index.php?rid=2665279&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05933.x Hepatitis E, caused by infection with hepatitis E virus (HEV), is a common cause of acute hepatitis in areas with poor sanitation. The virus has four genotypes with one serotype: genotypes 1 and 2 exclusively infect humans, whereas genotypes 3 and 4 also infect other animals, particularly pigs. In endemic areas, both large outbreaks of acute hepatitis as well as sporadic cases occur frequently. These cases are usually due to genotype 1 or 2 HEV and are predominantly caused by fecal[ndash]oral transmission, usually through contamination of drinking water; contaminated food, materno-fetal (vertical spread) and parenteral routes are less common modes of infection. The acute hepatitis caused by this virus has the highest attack rates in young adults and the disease is particularly severe among... Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2665279 Sun, 02 Aug 2009 23:00:00 +0100 2665279 Can preoperative CA19-9 and CEA levels predict the resectability of patients with pancreatic adenocarcinoma? http://www.medworm.com/index.php?rid=2665278&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05935.x Conclusion: The present study demonstrates that preoperative serum CA19-9 and CEA levels can be used for the prediction of resectability (R0 resection) in patients with pancreatic adenocarcinoma, which may enable a simple and cost-effective exclusion of such patients who are unlikely to benefit from surgery. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2665278 Sun, 02 Aug 2009 23:00:00 +0100 2665278 Diagnostic yield and therapeutic impact of single-balloon enteroscopy: Series of 106 cases http://www.medworm.com/index.php?rid=2665277&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05936.x Conclusion: SBE is well tolerated and has good diagnostic yield, having a similar yield to previous double-balloon enteroscopy reports. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2665277 Sun, 02 Aug 2009 23:00:00 +0100 2665277 Optimal dose of intravenous pantoprazole in patients with peptic ulcer bleeding requiring endoscopic hemostasis in Korea http://www.medworm.com/index.php?rid=2665276&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05939.x Conclusions: A continuous infusion, regardless of high or low dose, was more effective for acid suppression than a 40 mg bolus PPI injection in Korea. H. pylori infection was an important factor for the maintenance of an intragastric pH > 6. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2665276 Sun, 02 Aug 2009 23:00:00 +0100 2665276 Trunk strength and mobility changes in children with slow transit constipation http://www.medworm.com/index.php?rid=2665275&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05940.x Conclusion: The results show that STC children have reduced trunk control and posture, which indicates that clinicians should include training of trunk muscles and correction of sitting posture. There was no evidence that children with STC exercised less than the controls. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2665275 Sun, 02 Aug 2009 23:00:00 +0100 2665275 Rapamycin prevents Concanavalin A-induced liver injury by inhibiting lymphocyte activation http://www.medworm.com/index.php?rid=2449575&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05866.x Conclusion: These findings suggested that Rapa has the therapeutic potential for treatment of immune-mediated liver injury in the clinic. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2449575 Tue, 02 Jun 2009 04:00:00 +0100 2449575 Uridine diphosphate glucuronosyl transferase 1A1 promoter polymorphism is associated with choledocholithiasis in Taiwanese patients http://www.medworm.com/index.php?rid=2444074&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05867.x Conclusions: The results suggest that the UGT1A1 promoter TA-repeat polymorphism is associated with choledocholithiasis in Taiwanese patients. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2444074 Sat, 30 May 2009 04:00:00 +0100 2444074 Multiple primary malignancies in Spanish patients with hepatocellular carcinoma: Analysis of a hospital-based tumor registry http://www.medworm.com/index.php?rid=2444078&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05793.x Conclusions: EHPM is not rare among Spanish patients with HCC, although no specific clinicopathological features were detected in this population. Our results suggest that the association of another primary tumor with HCC does not imply a worse prognosis. The possibility of development of EHPM should be kept in mind when deciding on therapy and follow-up of HCC. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2444078 Thu, 28 May 2009 04:00:00 +0100 2444078 Cytosine deaminase-producing human mesenchymal stem cells mediate an antitumor effect in a mouse xenograft model http://www.medworm.com/index.php?rid=2444077&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05862.x Conclusion: The CD-hMSC system showed anticancer therapeutic potential, and minimized the side-effects of 5-FU. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2444077 Thu, 28 May 2009 04:00:00 +0100 2444077 Combination therapy with transarterial chemoembolization and interferon-α compared with transarterial chemoembolization alone for hepatitis B virus related unresectable hepatocellular carcinoma http://www.medworm.com/index.php?rid=2444076&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05863.x Conclusions: IFN-[alpha] treatment reduced recurrence and improved the survival of patients after TACE treatment of HBV-related HCC, with acceptable toxicities. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2444076 Thu, 28 May 2009 04:00:00 +0100 2444076 Characterization of hepatitis B virus reverse transcriptase sequences in Chinese treatment naive patients http://www.medworm.com/index.php?rid=2444075&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05864.x Conclusion: Primarily antiviral resistance related mutant strains do exist in treatment naïve patients. Without antiviral pressure, HBV strains evolved at a normal speed. In depth sequence analysis implied that viral replication might be correlated with its variability, which needs to be further investigated. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2444075 Thu, 28 May 2009 04:00:00 +0100 2444075 Opioid receptor antagonist promotes angiogenesis in bile duct ligated rats http://www.medworm.com/index.php?rid=2434391&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05794.x Conclusion: In order to clarify the impacts of opioid system blockade in cirrhosis, our findings demonstrate the promoting role of opioid antagonist in angiogenesis in a rat model of cholestasis. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2434391 Wed, 27 May 2009 01:25:13 +0100 2434391 Endoscopic treatment as first-line therapy for pancreatic ascites and pleural effusion http://www.medworm.com/index.php?rid=2434392&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05796.x Conclusion: Endoscopic therapy offers an excellent therapeutic alternative in patients with pancreatic ascites and pleural effusion. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2434392 Tue, 26 May 2009 04:00:00 +0100 2434392 Prevalence and risk factors for non-alcoholic fatty liver disease among adults in an urban Sri Lankan population http://www.medworm.com/index.php?rid=2425204&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05831.x Conclusion: The prevalence of NAFLD among adults in this urban Sri Lankan community is high and is strongly associated with constituent features of the metabolic syndrome. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2425204 Wed, 20 May 2009 04:00:00 +0100 2425204 Clinical fate of branch duct and mixed forms of intraductal papillary mucinous neoplasia of the pancreas http://www.medworm.com/index.php?rid=2425207&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05826.x Conclusion: Patients with the mixed form of IPMN as well as with symptomatic branch duct IPMN should require pancreatic resection because of symptoms and the risk for malignancy. In silent branch duct IPMN without radiological signs of malignancy, a non-operative watch-and-wait strategy can be discussed. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2425207 Tue, 19 May 2009 04:00:00 +0100 2425207 Resistance to metronidazole, clarithromycin and levofloxacin of Helicobacter pylori before and after clarithromycin-based therapy in Taiwan http://www.medworm.com/index.php?rid=2425206&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05829.x Conclusion: The levofloxacin resistance of naive H. pylori remains less than 10% in Taiwan. With relatively lower resistance to levofloxacin than to metronidazole of the H. pylori isolates collected after a failed clarithromycin-based therapy, proton pump inhibitor[ndash]levofloxacin[ndash]amoxicillin may be an alternative choice to serve as the second-line therapy. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2425206 Tue, 19 May 2009 04:00:00 +0100 2425206 Gastroscopy in immigrants of Turkish descent http://www.medworm.com/index.php?rid=2425205&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05830.x Conclusion: There are differences in the presence of ulcer disease and reflux esophagitis between Turkish men and women. Men are significantly more often H. pylori-positive. Prevalence of H. pylori infection in Turkish patients slowly decreases in the consecutive years in both men and women. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2425205 Tue, 19 May 2009 04:00:00 +0100 2425205 Comparison of one-week and two-week empirical trial with a high-dose rabeprazole in non-cardiac chest pain patients http://www.medworm.com/index.php?rid=2407843&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05859.x Conclusions: The rabeprazole empirical trial was diagnostic for patients with GERD-related NCCP, and its optimal duration was determined to be at least two weeks. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2407843 Fri, 15 May 2009 04:00:00 +0100 2407843 Factors affecting recurrence in node-negative advanced gastric cancer http://www.medworm.com/index.php?rid=2407847&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05844.x Conclusion: Node-negative advanced gastric cancer has more peritoneal seeding and locoregional recurrence. Aggressive cell behavior predicted the route of tumor cell spreading. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2407847 Sun, 10 May 2009 04:00:00 +0100 2407847 Management of the rare entity of primary pancreatic cystic neoplasms http://www.medworm.com/index.php?rid=2407846&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05855.x Primary cystic neoplasms of the pancreas constitute a rare entity and are composed of a variety of neoplasms with a wide range of malignant potential. Approximately 90% of these lesions are serous cystic neoplasms or mucin-producing neoplasms. In contrast to serous cystadenomas which are nearly always benign, the mucinous cystic neoplasms represent a more diverse, heterogenous spectrum of related neoplasms. Intraductal papillary mucinous neoplasms manifest a much greater latent or overt malignant potential than other cystic neoplasms of the pancreas. The various subgroups of cystic neoplasms of the pancreas are evaluated and compared through a review of current literature. No symptoms or signs are pathognomonic for the cystic pancreatic neoplasms. While identification of a cystic tumor is ... Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2407846 Sun, 10 May 2009 04:00:00 +0100 2407846 Feasibility of self-expandable metallic stent plus chemotherapy for metastatic gastric cancer with pyloric stenosis http://www.medworm.com/index.php?rid=2407845&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05857.x Conclusions: The present results suggest that chemotherapy after stenting is as effective and safe as chemotherapy after surgery. Stents may replace surgery in combination therapy with chemotherapy for metastatic gastric cancer with gastric outlet obstruction. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2407845 Sun, 10 May 2009 04:00:00 +0100 2407845 Metabolic risk factors associated with erosive esophagitis http://www.medworm.com/index.php?rid=2407844&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05858.x Conclusions: Obesity and hypertriglyceridemia, which are key components of metabolic syndrome, are moderate independent risk factors for erosive esophagitis. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2407844 Sun, 10 May 2009 04:00:00 +0100 2407844 Increased liver stiffness measurement by transient elastography in severe acute exacerbation of chronic hepatitis B http://www.medworm.com/index.php?rid=2360385&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05779.x Conclusions: LSM using transient elastography with the current proposed cut-off values might misdiagnose liver cirrhosis in patients suffering from severe acute exacerbation of CHB. LSM should be assessed after normalization of ALT levels in order to accurately assess the degree of fibrosis. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2360385 Fri, 24 Apr 2009 04:00:00 +0100 2360385 An evaluation of the potential cost-effectiveness of non-invasive testing strategies in the diagnosis of significant liver fibrosis http://www.medworm.com/index.php?rid=2360386&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05778.x Conclusions: The results of our study suggest that compared with liver biopsy, non-invasive testing algorithms can result in short-term cost savings, but the consequences of misdiagnosis in terms of health outcomes and treatment costs might outweigh the short-term gains in cost and convenience. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2360386 Thu, 23 Apr 2009 04:00:00 +0100 2360386 Evaluation of esophageal varices on liver computed tomography: Receiver operating characteristic analyses of the performance of radiologists and endoscopists http://www.medworm.com/index.php?rid=2333794&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05849.x Conclusions: Experienced readers have a better ability to detect esophageal varices on liver MDCT, but had no higher performance to evaluate high-risk esophageal varices. As the accuracy of detecting high-risk esophageal varices with clinical relevance on liver MDCT is excellent, even by endoscopists, the evaluation of esophageal varices from a recent liver MDCT may be useful to avoid the use of low-yield endoscopy. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2333794 Fri, 17 Apr 2009 04:00:00 +0100 2333794 The preliminary experimental and clinical study of the relationship between the pigment gallstone and intestinal mucosal barrier http://www.medworm.com/index.php?rid=2333799&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05842.x Conclusions: The formation of pigment gallstone was related to the abnormal function of the intestinal mucosal barrier. The abnormality in the function of the intestinal mucosal barrier probably induced the formation of gallstone by a bacterial translocation mechanism. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2333799 Mon, 13 Apr 2009 04:00:00 +0100 2333799 Effects of muscarinic receptor stimulation and nitric oxide synthase inhibition on gastric tone and gastric myoelectrical activity in canines http://www.medworm.com/index.php?rid=2333798&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05843.x Conclusions: Muscarinic receptor stimulation and nitric oxide synthase inhibition have similar effects on gastric tone and gastric spike activities, but different effects on gastric slow waves. Gastric fundic tone does not correlate with gastric slow waves. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2333798 Mon, 13 Apr 2009 04:00:00 +0100 2333798 Performance of acidified 14C-urea capsule breath test during pantoprazole and ranitidine treatment http://www.medworm.com/index.php?rid=2333797&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05845.x Conclusions: The use of acidified 14C-urea capsule did not prevent false negative UBT results in patients taking pantoprazole and ranitidine, and the duration of medication does not affect the test results. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2333797 Mon, 13 Apr 2009 04:00:00 +0100 2333797 Identification of a novel protein binding to hepatitis C virus core protein http://www.medworm.com/index.php?rid=2333796&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05846.x Conclusion: Our data suggest that ACY3 is an HCV core binding protein, which may play a role in the development of HCV-associated diseases. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2333796 Mon, 13 Apr 2009 04:00:00 +0100 2333796 Predictors of microscopic portal vein invasion by hepatocellular carcinoma: Measurement of portal perfusion defect area ratio http://www.medworm.com/index.php?rid=2333795&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05847.x Objective: Microscopic portal vein invasion (PVI) by cancer cells is a poor prognostic factor after hepatic resection for hepatocellular carcinoma (HCC). The aim of this study is to predict PVI preoperatively in patients with HCC.Methods: We studied 46 hepatectomized patients who had HCC without any portal venous invasion detected during preoperative radiographic evaluation. We defined the portal perfusion defect area ratio (PPDAR) as the following: the quotient of the maximal portal perfusion defect area, on computed tomography during arterio-portography (CTAP) is divided by the maximal tumor area on magnetic resonance imaging (MRI) or CT.Results: The median PPDAR was 1.3 (mean 1.4 ± 1.1; ranged from 0.7 to 5.8). The incidence of PVI was 4.5% in patients with a PPDAR (Source: Journal of ... Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2333795 Mon, 13 Apr 2009 04:00:00 +0100 2333795 Comparison of outcomes between patients with alcoholic cirrhosis and those with hepatitis C virus-related cirrhosis http://www.medworm.com/index.php?rid=2309527&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05851.x Conclusions: Survival of patients with alcoholic cirrhosis was similar to that of patients with HCV-related cirrhosis. The risk of HCC development was lower in alcoholic cirrhosis than in HCV-related cirrhosis. Abstinence from alcohol was important for improving the survival of patients with alcoholic cirrhosis. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2309527 Tue, 07 Apr 2009 04:00:00 +0100 2309527 Chronic hepatitis B infection in an Australian antenatal population: seroprevalence and opportunities for better outcomes http://www.medworm.com/index.php?rid=2309533&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05841.x Conclusion: It is clear that chronic HBV infection is prevalent in the antenatal population. However, there are no strategies to ensure that infected mothers subsequently undergo further education for HBV or evaluation of infectivity. Clearly strategies are required to ensure improved follow up of hepatitis B infected mothers. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2309533 Mon, 06 Apr 2009 04:00:00 +0100 2309533 Clinical manifestations and survival of hepatocellular carcinoma patients with peritoneal metastasis http://www.medworm.com/index.php?rid=2309531&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05848.x Conclusions: Peritoneal metastases of HCC are rare and can occur synchronously or metachronously. Though increased long-term survival was found in patients who had surgical removal of peritoneal metastases, the main determinant of better survival is Child-Pugh grade. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2309531 Mon, 06 Apr 2009 04:00:00 +0100 2309531 Efficacy of a single 24-hour pre-anesthetic dose of proton pump inhibitors http://www.medworm.com/index.php?rid=2309529&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05850.x Conclusion: Single rabeprazole (but not lansoperazole) medication may be a suitable alternative to standard roxatidine for prophylaxis of acid aspiration pneumonia. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2309529 Mon, 06 Apr 2009 04:00:00 +0100 2309529 Endoscopic retrograde pancreatography in pancreatic trauma: Need to break the mental barrier http://www.medworm.com/index.php?rid=2263674&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05809.x Pancreatic injury has a high morbidity and mortality. The integrity of the main pancreatic duct is the most important determinant of prognosis. Serum amylase, peritoneal lavage and computed tomography of the abdomen can assist with diagnosis but endoscopic retrograde pancreatography (ERP) is the most accurate investigation for diagnosing the site and extent of ductal disruption. However, it is invasive and can be associated with significant complications. Magnetic resonance cholangiopancreatography (MRCP) and secretin-enhanced MRCP probably parallel ERP in delineating pancreatic ductal injuries. They can also delineate the duct upstream to complete disruption, an area not visualized on ERP. In relation to therapy, endoscopic transpapillary drainage has been successfully used to heal duct d... Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2263674 Sat, 14 Mar 2009 04:00:00 +0100 2263674 Increased heat-shock protein 90 expression contributes to impaired adaptive cytoprotection in the gastric mucosa of portal hypertensive rats http://www.medworm.com/index.php?rid=2263689&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2008.05763.x Conclusions: These results show that 10% ethanol pretreatment markedly increases gastric Hsp90 expression in PHT rats. Excessive production of Hsp90 may contribute impaired adaptive cytoprotection. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2263689 Wed, 11 Mar 2009 04:00:00 +0100 2263689 Application of surveillance programs for hepatocellular carcinoma in the Asia–Pacific Region http://www.medworm.com/index.php?rid=2263686&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05805.x In conclusion, HCC surveillance could be effective at reducing disease-specific mortality with acceptable cost-effectiveness among selected patient groups, provided it is a well-organized program. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2263686 Wed, 11 Mar 2009 04:00:00 +0100 2263686 Application of per oral cholangiopancreatoscopy in pancreatobiliary diseases http://www.medworm.com/index.php?rid=2263683&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05808.x Pancreaticobiliary ductal diseases are largely investigated by indirect imaging techniques. Therefore, the pathology of up to 30% of cases remains undetermined. Cholangiopancreatoscopy allows direct visualization of ductal abnormalities with the ability to sample tissue and deliver a number of endotherapies. The technique can be broadly categorized into either two-operator or single-operator systems. Both systems provide important diagnostic information in the investigation of undetermined biliary or pancreatic strictures, intraductal papillary mucinous neoplasia, occult ductal malignant changes in patients with primary sclerosing cholangitis and occult intraductal stones in patients with complex biliary stone diseases. Therapeutically, cholangiopancreatoscopy-guided endotherapies provide ... Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2263683 Wed, 11 Mar 2009 04:00:00 +0100 2263683 Significance of lymphatic invasion and cancer invasion-related proteins on lymph node metastasis in gastric cancer http://www.medworm.com/index.php?rid=2263680&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05810.x Conclusion: Among the cancer invasion-related proteins examined, MMP-1 plays a vital role in LN metastasis of gastric cancer. Tumor size, lymphatic invasion and MMP-1 expression level at the invasive front were the predictive factors of LN metastasis of gastric cancer. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2263680 Wed, 11 Mar 2009 04:00:00 +0100 2263680 Benefits of endoscopic submucosal dissection according to size and location of gastric neoplasm, compared with conventional mucosal resection http://www.medworm.com/index.php?rid=2263678&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05811.x Conclusion: We concluded that lesions exceeding 5 mm in diameter should be treated by ESD, although a high resection rate is obtained also with EMR for lesions of 5 mm or less in diameter. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2263678 Wed, 11 Mar 2009 04:00:00 +0100 2263678 Thyroid dysfunction in patients with chronic hepatitis C: Virus- or therapy-related? http://www.medworm.com/index.php?rid=2263676&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05812.x Conclusion: Antiviral therapy of CHC possibly induces de novo or exacerbates pre-existing silent TD. TD does not seem to correlate with any pretreatment virological parameter; it is probably not related to dose or treatment duration, nor linked to viral kinetics or virological outcome. The role of chronic hepatitis C per se in TD remains to be determined. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2263676 Wed, 11 Mar 2009 04:00:00 +0100 2263676 Apoptosis in experimental NASH is associated with p53 activation and TRAIL receptor expression http://www.medworm.com/index.php?rid=2189902&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05785.x Conclusions: Methionine and choline deficiency lower IGF-1 to de-repress p53 during induction of steatohepatitis. The p53 induced by nutritional stress is biologically active in mediating mitochondrial cell death pathways, but may also be responsible for TRAIL receptor expression, thereby linking intrinsic and exogenous apoptosis pathways in NASH. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2189902 Tue, 17 Feb 2009 05:00:00 +0100 2189902 Increased plasma nitric oxide, L-arginine, and arginase-1 in cirrhotic patients with progressive renal dysfunction http://www.medworm.com/index.php?rid=2189907&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2008.05757.x Conclusion: Worsening renal function in decompensated cirrhosis is accompanied by progressive elevation in plasma NOx and L-Arg. These findings support the hypothesis that NO-mediated vasodilation is probably linked with the mechanism of progressive renal failure in decompensated cirrhotics. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2189907 Sun, 15 Feb 2009 05:00:00 +0100 2189907 Efficacy of entecavir treatment for lamivudine-resistant hepatitis B over 3 years: Histological improvement or entecavir resistance? http://www.medworm.com/index.php?rid=2189906&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2008.05760.x Conclusion: Entecavir in the long term would be useful for histological improvement of breakthrough hepatitis induced by lamivudine-resistant HBV mutants in patients with chronic hepatitis B. However, the relatively high rate of entecavir resistance is a concern, and other strategies need to be considered when available. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2189906 Sun, 15 Feb 2009 05:00:00 +0100 2189906 Relationship between Helicobacter pylori hopQ genotype and clinical outcome in Asian and Western populations http://www.medworm.com/index.php?rid=2189905&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2008.05762.x Conclusion: The expression of multiple putative virulence factors in Asian strains likely explains the relatively high incidence of clinical outcomes including gastric cancer compared with other parts of the world. Although hopQ genotype did not improve the predictive value above other genotyping for development of H. pylori-related gastroduodenal diseases, the hopQ genotype might be able to add a useful virulence marker for gastroduodenal diseases. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2189905 Sun, 15 Feb 2009 05:00:00 +0100 2189905 Retinoid metabolism in the small intestine during development of liver cirrhosis http://www.medworm.com/index.php?rid=2189904&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2008.05771.x Conclusion: These results suggest that altered retinoid metabolism in the intestine of cirrhotic rats might have an influence on changes in intestinal epithelial cell differentiation, seen in liver cirrhosis. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2189904 Sun, 15 Feb 2009 05:00:00 +0100 2189904 Therapeutic approach to regulate innate immune response by Toll-like receptor 4 antagonist E5564 in rats with D-galactosamine-induced acute severe liver injury http://www.medworm.com/index.php?rid=2189903&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2008.05770.x Conclusion: TLR4 antagonist E5564 reduced GalN-induced ALI in rats. It may contribute to the treatment of acute liver failure through blocking endotoxin-induced TNF-[alpha] overproduction of macrophages. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2189903 Sun, 15 Feb 2009 05:00:00 +0100 2189903 Single-operator double-balloon endoscopy (DBE) is as effective as dual-operator DBE http://www.medworm.com/index.php?rid=2180932&cid=s_30386_17_f&fid=30386&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1746.2009.05787.x Conclusions: The single-operator method for DBE was as efficient as the dual-operator DBE without any higher risk of complications and, therefore, could replace the conventional dual-operator method in the future. (Source: Journal of Gastroenterology and Hepatology) Journal of Gastroenterology and Hepatology journals http://www.medworm.com/rss/comments.php?id=2180932 Fri, 13 Feb 2009 05:00:00 +0100 2180932