Journal of Medicinal Chemistry via MedWorm.com MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Journal of Medicinal Chemistry' source. Sat, 20 Mar 2010 15:58:16 +0100 (1S)-1,5-Anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4-methylphenyl]-1-thio-d-glucitol (TS-071) is a Potent, Selective Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Inhibitor for Type 2 Diabetes Treatment http://www.medworm.com/index.php?rid=3384999&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901893x%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3384999 Sat, 20 Mar 2010 10:05:20 +0100 3384999 Cyclic Sulfones as Novel P3-Caps for Hepatitis C Virus NS3/4A (HCV NS3/4A) Protease Inhibitors: Synthesis and Evaluation of Inhibitors with Improved Potency and Pharmacokinetic Profiles http://www.medworm.com/index.php?rid=3385000&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm9016027%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3385000 Fri, 19 Mar 2010 15:26:20 +0100 3385000 Structure−Activity Relationships in Toll-like Receptor-2 Agonistic Diacylthioglycerol Lipopeptides http://www.medworm.com/index.php?rid=3385001&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901839g%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3385001 Fri, 19 Mar 2010 15:26:06 +0100 3385001 Targeted Delivery of Paclitaxel to Tumor Cells: Synthesis and in Vitro Evaluation http://www.medworm.com/index.php?rid=3385002&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901763f%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3385002 Fri, 19 Mar 2010 15:24:51 +0100 3385002 Discovery of Novel Small Molecule Orally Bioavailable C−X−C Chemokine Receptor 4 Antagonists That Are Potent Inhibitors of T-Tropic (X4) HIV-1 Replication http://www.medworm.com/index.php?rid=3385003&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm100073m%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3385003 Fri, 19 Mar 2010 11:46:04 +0100 3385003 Modulation of Cell Surface Expression of Nonactivated Cholecystokinin Receptors Using Bivalent Ligand-Induced Internalization http://www.medworm.com/index.php?rid=3381984&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm100135g%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3381984 Fri, 19 Mar 2010 10:03:16 +0100 3381984 An Analysis of the Binding Efficiencies of Drugs and Their Leads in Successful Drug Discovery Programs http://www.medworm.com/index.php?rid=3377548&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm100118x%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3377548 Thu, 18 Mar 2010 10:04:15 +0100 3377548 Synthesis and Biological Evaluation of 8-Oxoadenine Derivatives as Toll-like Receptor 7 Agonists Introducing the Antedrug Concept http://www.medworm.com/index.php?rid=3373377&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm100070n%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3373377 Wed, 17 Mar 2010 10:03:25 +0100 3373377 The Impact of Polyether Chain Length on the Iron Clearing Efficiency and Physiochemical Properties of Desferrithiocin Analogues http://www.medworm.com/index.php?rid=3373378&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm9018146%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3373378 Tue, 16 Mar 2010 12:34:13 +0100 3373378 Improving Binding Specificity of Pharmacological Chaperones That Target Mutant Superoxide Dismutase-1 Linked to Familial Amyotrophic Lateral Sclerosis Using Computational Methods http://www.medworm.com/index.php?rid=3373379&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901062p%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3373379 Tue, 16 Mar 2010 12:33:02 +0100 3373379 Chemical Fragments that Hydrogen Bond to Asp, Glu, Arg, and His Side Chains in Protein Binding Sites http://www.medworm.com/index.php?rid=3369510&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901696w%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3369510 Tue, 16 Mar 2010 10:04:10 +0100 3369510 Synthesis, Antitubulin, and Antiproliferative SAR of Analogues of 2-Methoxyestradiol-3,17-O,O-bis-sulfamate http://www.medworm.com/index.php?rid=3361964&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm9018806%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3361964 Sat, 13 Mar 2010 11:04:01 +0100 3361964 Synthesis and Biological Evaluation of 4-Anilinoquinolines as Potent Inhibitors of Epidermal Growth Factor Receptor http://www.medworm.com/index.php?rid=3358099&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901877j%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3358099 Fri, 12 Mar 2010 11:03:51 +0100 3358099 Complexity in Influenza Virus Targeted Drug Design: Interaction with Human Sialidases http://www.medworm.com/index.php?rid=3358100&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm100078r%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3358100 Thu, 11 Mar 2010 18:01:13 +0100 3358100 Exploring the Structural Requirements for Inhibition of the Ubiquitin E3 Ligase Breast Cancer Associated Protein 2 (BCA2) as a Treatment for Breast Cancer http://www.medworm.com/index.php?rid=3358101&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901757t%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3358101 Thu, 11 Mar 2010 14:36:48 +0100 3358101 Structure−Activity Relationship for Thiohydantoin Androgen Receptor Antagonists for Castration-Resistant Prostate Cancer (CRPC) http://www.medworm.com/index.php?rid=3353567&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901488g%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3353567 Thu, 11 Mar 2010 11:04:06 +0100 3353567 Modified Cap Group Suberoylanilide Hydroxamic Acid Histone Deacetylase Inhibitor Derivatives Reveal Improved Selective Antileukemic Activity http://www.medworm.com/index.php?rid=3353568&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901358y%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3353568 Wed, 10 Mar 2010 16:34:30 +0100 3353568 Structure−Activity Relationships of Monomeric C2-Aryl Pyrrolo[2,1-c][1,4]benzodiazepine (PBD) Antitumor Agents http://www.medworm.com/index.php?rid=3353569&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901722v%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3353569 Wed, 10 Mar 2010 14:19:45 +0100 3353569 “Carba”-Analogues of Fentanyl are Opioid Receptor Agonists‡‡Dedicated to the memory of Ralph F. Hirschmann http://www.medworm.com/index.php?rid=3353570&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm9019068%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3353570 Wed, 10 Mar 2010 14:19:31 +0100 3353570 Emerging Targets in Osteoporosis Disease Modification http://www.medworm.com/index.php?rid=3353572&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm9018756%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3353572 Wed, 10 Mar 2010 14:19:28 +0100 3353572 Synthesis and in Vitro Biological Evaluation of Carbonyl Group-Containing Inhibitors of Vesicular Acetylcholine Transporter http://www.medworm.com/index.php?rid=3353571&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm9017916%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3353571 Wed, 10 Mar 2010 14:19:28 +0100 3353571 Discovery of an Oxybenzylglycine Based Peroxisome Proliferator Activated Receptor α Selective Agonist 2-((3-((2-(4-Chlorophenyl)-5-methyloxazol-4-yl)methoxy)benzyl)(methoxycarbonyl)amino)acetic Acid (BMS-687453) http://www.medworm.com/index.php?rid=3353573&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm9016812%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3353573 Wed, 10 Mar 2010 14:16:25 +0100 3353573 3′-[4-Aryl-(1,2,3-triazol-1-yl)]-3′-deoxythymidine Analogues as Potent and Selective Inhibitors of Human Mitochondrial Thymidine Kinase http://www.medworm.com/index.php?rid=3353574&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901532h%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3353574 Wed, 10 Mar 2010 14:15:56 +0100 3353574 A Virtual Screening Hit Reveals New Possibilities for Developing Group III Metabotropic Glutamate Receptor Agonists http://www.medworm.com/index.php?rid=3353575&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901523t%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3353575 Wed, 10 Mar 2010 14:14:27 +0100 3353575 Discovery and Evaluation of 7-Alkyl-1,5-bis-aryl-pyrazolopyridinones as Highly Potent, Selective, and Orally Efficacious Inhibitors of p38α Mitogen-Activated Protein Kinase⊥⊥Atomic coordinates and structure factors for crystal structure of compound 3d with p38α can be accessed using PDB code 3LHJ http://www.medworm.com/index.php?rid=3353576&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm100095x%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3353576 Wed, 10 Mar 2010 14:14:20 +0100 3353576 New Angiopep-Modified Doxorubicin (ANG1007) and Etoposide (ANG1009) Chemotherapeutics With Increased Brain Penetration http://www.medworm.com/index.php?rid=3349574&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm9016637%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3349574 Tue, 09 Mar 2010 15:42:02 +0100 3349574 Radiosynthesis and Bioimaging of the Tuberculosis Chemotherapeutics Isoniazid, Rifampicin and Pyrazinamide in Baboons http://www.medworm.com/index.php?rid=3349575&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901858n%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3349575 Mon, 08 Mar 2010 12:13:29 +0100 3349575 Erratum: Corrections to Cationic Amphiphile with Shikimic Acid Headgroup Shows More Systemic Promise Than Its Mannosyl Analogue as DNA Vaccine Carrier in Dendritic Cell Based Genetic Immunization http://www.medworm.com/index.php?rid=3337655&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm100267e%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3337655 Sat, 06 Mar 2010 11:04:34 +0100 3337655 Discovery, Biological Evaluation, and Structure−Activity Relationship of Amidine Based Sphingosine Kinase Inhibitors http://www.medworm.com/index.php?rid=3337656&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901860h%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3337656 Fri, 05 Mar 2010 14:42:47 +0100 3337656 Conformational Refinement of Hydroxamate-Based Histone Deacetylase Inhibitors and Exploration of 3-Piperidin-3-ylindole Analogues of Dacinostat (LAQ824) http://www.medworm.com/index.php?rid=3337657&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm100007m%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3337657 Fri, 05 Mar 2010 14:42:32 +0100 3337657 2009 Reviewers http://www.medworm.com/index.php?rid=3337658&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm100264u%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3337658 Fri, 05 Mar 2010 14:42:30 +0100 3337658 Sulfonamide Linked Neoglycoconjugates−A New Class of Inhibitors for Cancer-Associated Carbonic Anhydrases http://www.medworm.com/index.php?rid=3334498&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901888x%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3334498 Fri, 05 Mar 2010 11:05:02 +0100 3334498 Development of Novel, Highly Potent Inhibitors of V-RAF Murine Sarcoma Viral Oncogene Homologue B1 (BRAF): Increasing Cellular Potency through Optimization of a Distal Heteroaromatic Group http://www.medworm.com/index.php?rid=3330613&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm900607f%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3330613 Thu, 04 Mar 2010 11:04:20 +0100 3330613 In Vitro and In Vivo Photocytotoxicity of Boron Dipyrromethene Derivatives for Photodynamic Therapy http://www.medworm.com/index.php?rid=3326172&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901823u%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3326172 Wed, 03 Mar 2010 13:25:01 +0100 3326172 Design, Synthesis, and Biological Evaluation of 3-[4-(2-Hydroxyethyl)piperazin-1-yl]-7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)pyrido[3,4-b]pyrazin-2(1H)-one, a Potent, Orally Active, Brain Penetrant Inhibitor of Phosphodiesterase 5 (PDE5) http://www.medworm.com/index.php?rid=3326173&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901781q%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3326173 Tue, 02 Mar 2010 20:21:27 +0100 3326173 Book Review of Comprehensive Organic Name Reactions and Reagents http://www.medworm.com/index.php?rid=3326174&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm100232f%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3326174 Tue, 02 Mar 2010 20:20:03 +0100 3326174 Structure−Activity Relationship of (N)-Methanocarba Phosphonate Analogues of 5′-AMP as Cardioprotective Agents Acting Through a Cardiac P2X Receptor http://www.medworm.com/index.php?rid=3321527&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm9018542%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3321527 Mon, 01 Mar 2010 17:56:18 +0100 3321527 Synthesis and QSAR of Quinazoline Sulfonamides As Highly Potent Human Histamine H4 Receptor Inverse Agonists http://www.medworm.com/index.php?rid=3317856&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901379s%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3317856 Mon, 01 Mar 2010 14:11:22 +0100 3317856 Fragment-Based Deconstruction of Bcl-xL Inhibitors http://www.medworm.com/index.php?rid=3317857&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm100009z%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3317857 Mon, 01 Mar 2010 14:10:09 +0100 3317857 Discovery of a Biaryl Cyclohexene Carboxylic Acid (MK-6892): A Potent and Selective High Affinity Niacin Receptor Full Agonist with Reduced Flushing Profiles in Animals as a Preclinical Candidate http://www.medworm.com/index.php?rid=3305950&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm100022r%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3305950 Thu, 25 Feb 2010 15:29:17 +0100 3305950 Fluorescent Epigenetic Small Molecule Induces Expression of the Tumor Suppressor Ras-Association Domain Family 1A and Inhibits Human Prostate Xenograft http://www.medworm.com/index.php?rid=3305951&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm9011615%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3305951 Thu, 25 Feb 2010 15:26:34 +0100 3305951 Identification of Inhibitors of Drug-Resistant Candida albicans Strains from a Library of Bicyclic Peptidomimetic Compounds http://www.medworm.com/index.php?rid=3305952&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901734u%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3305952 Thu, 25 Feb 2010 15:26:32 +0100 3305952 Dopamine Receptor Ligands. Part 18:(1) Modification of the Structural Skeleton of Indolobenzazecine-Type Dopamine Receptor Antagonists http://www.medworm.com/index.php?rid=3305953&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901291r%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3305953 Wed, 24 Feb 2010 18:01:56 +0100 3305953 Membrane Permeable Cyclic Peptidyl Inhibitors against Human Peptidylprolyl Isomerase Pin1 http://www.medworm.com/index.php?rid=3301332&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901778v%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3301332 Wed, 24 Feb 2010 14:06:58 +0100 3301332 Discovery of a Novel Series of Semisynthetic Vancomycin Derivatives Effective against Vancomycin-Resistant Bacteria http://www.medworm.com/index.php?rid=3301333&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm9017543%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3301333 Wed, 24 Feb 2010 14:03:32 +0100 3301333 Prediction and Evaluation of Protein Farnesyltransferase Inhibition by Commercial Drugs http://www.medworm.com/index.php?rid=3301334&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901613f%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3301334 Wed, 24 Feb 2010 14:02:26 +0100 3301334 Potent Arylsulfonamide Inhibitors of Tumor Necrosis Factor-α Converting Enzyme Able to Reduce Activated Leukocyte Cell Adhesion Molecule Shedding in Cancer Cell Models http://www.medworm.com/index.php?rid=3301335&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901868z%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3301335 Wed, 24 Feb 2010 13:01:08 +0100 3301335 Discovery of Dipeptides with High Affinity to the Specific Binding Site for Substance P1−7 http://www.medworm.com/index.php?rid=3297685&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901352b%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3297685 Tue, 23 Feb 2010 15:51:42 +0100 3297685 Discovery and SAR of Thiazolidine-2,4-dione Analogues as Insulin-like Growth Factor-1 Receptor (IGF-1R) Inhibitors via Hierarchical Virtual Screening http://www.medworm.com/index.php?rid=3297686&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901798e%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3297686 Tue, 23 Feb 2010 15:49:21 +0100 3297686 Intramolecular Hydrogen Bonding in Medicinal Chemistry http://www.medworm.com/index.php?rid=3297687&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm100087s%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3297687 Mon, 22 Feb 2010 17:11:23 +0100 3297687 A Novel Insulin Secretagogue Based on a Dinucleoside Polyphosphate Scaffold(1) http://www.medworm.com/index.php?rid=3297688&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901621h%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3297688 Mon, 22 Feb 2010 16:36:06 +0100 3297688 Synthesis, Biological Activity, and Molecular Modeling Studies of 1H-1,2,3-Triazole Derivatives of Carbohydrates as α-Glucosidases Inhibitors http://www.medworm.com/index.php?rid=3290366&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901265h%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3290366 Fri, 19 Feb 2010 21:32:52 +0100 3290366 1-(Aryl)-6-[alkoxyalkyl]-3-azabicyclo[3.1.0]hexanes and 6-(Aryl)-6-[alkoxyalkyl]-3-azabicyclo[3.1.0]hexanes: A New Series of Potent and Selective Triple Reuptake Inhibitors http://www.medworm.com/index.php?rid=3290367&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901818u%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3290367 Fri, 19 Feb 2010 21:24:19 +0100 3290367 Development of Novel Adenosine Monophosphate-Activated Protein Kinase Activators http://www.medworm.com/index.php?rid=3290368&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901773d%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3290368 Fri, 19 Feb 2010 21:24:18 +0100 3290368 Identification of 2-Anilino-9-methoxy-5,7-dihydro-6H-pyrimido[5,4-d][1]benzazepin-6-ones as Dual PLK1/VEGF-R2 Kinase Inhibitor Chemotypes by Structure-Based Lead Generation http://www.medworm.com/index.php?rid=3290369&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901388c%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3290369 Fri, 19 Feb 2010 18:29:12 +0100 3290369 A New Class of Naphthalimide-Based Antitumor Agents That Inhibit Topoisomerase II and Induce Lysosomal Membrane Permeabilization and Apoptosis http://www.medworm.com/index.php?rid=3290370&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm100025u%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3290370 Fri, 19 Feb 2010 18:28:27 +0100 3290370 Noncovalent Tripeptidyl Benzyl- and Cyclohexyl-Amine Inhibitors of the Cysteine Protease Caspase-1 http://www.medworm.com/index.php?rid=3290371&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901790w%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3290371 Fri, 19 Feb 2010 18:24:42 +0100 3290371 N-Methyl Phenylalanine-Rich Peptides as Highly Versatile Blood−Brain Barrier Shuttles http://www.medworm.com/index.php?rid=3290372&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901654x%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3290372 Fri, 19 Feb 2010 16:11:29 +0100 3290372 Salicylic Acid Based Small Molecule Inhibitor for the Oncogenic Src Homology-2 Domain Containing Protein Tyrosine Phosphatase-2 (SHP2) http://www.medworm.com/index.php?rid=3287022&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901645u%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3287022 Fri, 19 Feb 2010 15:33:14 +0100 3287022 Novel Diamidino-Substituted Derivatives of Phenyl Benzothiazolyl and Dibenzothiazolyl Furans and Thiophenes: Synthesis, Antiproliferative and DNA Binding Properties http://www.medworm.com/index.php?rid=3287023&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901441b%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3287023 Fri, 19 Feb 2010 15:32:15 +0100 3287023 5-Cyclic Amine-3-arylsulfonylindazoles as Novel 5-HT6 Receptor Antagonists http://www.medworm.com/index.php?rid=3287025&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901674f%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3287025 Fri, 19 Feb 2010 15:31:57 +0100 3287025 Synthesis and Biological Activities of 2-Amino-1-arylidenamino Imidazoles as Orally Active Anticancer Agents http://www.medworm.com/index.php?rid=3287024&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901501s%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3287024 Fri, 19 Feb 2010 15:31:57 +0100 3287024 Identification of 3,4-Dihydroisoquinoline-2(1H)-sulfonamides as Potent Carbonic Anhydrase Inhibitors: Synthesis, Biological Evaluation, and Enzyme−Ligand X-ray Studies http://www.medworm.com/index.php?rid=3287026&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm9014026%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3287026 Fri, 19 Feb 2010 15:31:55 +0100 3287026 Synthesis and Characterization of Rhenium and Technetium-99m Labeled Insulin http://www.medworm.com/index.php?rid=3287027&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm100096c%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3287027 Fri, 19 Feb 2010 15:31:32 +0100 3287027 Bis(morpholino-1,3,5-triazine) Derivatives: Potent Adenosine 5′-Triphosphate Competitive Phosphatidylinositol-3-kinase/Mammalian Target of Rapamycin Inhibitors: Discovery of Compound 26 (PKI-587), a Highly Efficacious Dual Inhibitor http://www.medworm.com/index.php?rid=3287028&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901830p%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3287028 Thu, 18 Feb 2010 16:23:47 +0100 3287028 Discovery of Vaniprevir (MK-7009), a Macrocyclic Hepatitis C Virus NS3/4a Protease Inhibitor http://www.medworm.com/index.php?rid=3282913&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm9015526%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3282913 Thu, 18 Feb 2010 15:43:14 +0100 3282913 Piracetam Defines a New Binding Site for Allosteric Modulators of α-Amino-3-hydroxy-5-methyl-4-isoxazole-propionic Acid (AMPA) Receptors http://www.medworm.com/index.php?rid=3279275&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901905j%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3279275 Wed, 17 Feb 2010 14:05:50 +0100 3279275 The Discovery of 4-{1-[({2,5-Dimethyl-4-[4-(trifluoromethyl)benzyl]-3-thienyl}carbonyl)amino]cyclopropyl}benzoic Acid (MK-2894), A Potent and Selective Prostaglandin E2 Subtype 4 Receptor Antagonist† http://www.medworm.com/index.php?rid=3279276&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901771h%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3279276 Wed, 17 Feb 2010 13:55:36 +0100 3279276 Synthesis and Biological Evaluation of Bupropion Analogues as Potential Pharmacotherapies for Smoking Cessation http://www.medworm.com/index.php?rid=3275245&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm9017465%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3275245 Tue, 16 Feb 2010 15:34:46 +0100 3275245 Structural Insights into the Design of Small Molecule Inhibitors That Selectively Antagonize Mcl-1 http://www.medworm.com/index.php?rid=3275257&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901469p%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3275257 Tue, 16 Feb 2010 15:32:49 +0100 3275257 Hybrid Molecules from Xanomeline and Tacrine: Enhanced Tacrine Actions on Cholinesterases and Muscarinic M1 Receptors http://www.medworm.com/index.php?rid=3275246&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901616h%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3275246 Tue, 16 Feb 2010 15:31:32 +0100 3275246 Molecular Shape and Medicinal Chemistry: A Perspective http://www.medworm.com/index.php?rid=3275247&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm900818s%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3275247 Tue, 16 Feb 2010 13:35:34 +0100 3275247 Structural Basis for Platelet Antiaggregation by Angiotensin II Type 1 Receptor Antagonist Losartan (DuP-753) via Glycoprotein VI http://www.medworm.com/index.php?rid=3275249&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901534d%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3275249 Tue, 16 Feb 2010 13:34:28 +0100 3275249 Synthesis, in Vitro and in Vivo Biological Evaluation, Docking Studies, and Structure−Activity Relationship (SAR) Discussion of Dipeptidyl Boronic Acid Proteasome Inhibitors Composed of β-Amino Acids http://www.medworm.com/index.php?rid=3275248&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901407s%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3275248 Tue, 16 Feb 2010 13:34:28 +0100 3275248 1-Alkyl-4-phenyl-6-alkoxy-1H-quinazolin-2-ones: A Novel Series of Potent Calcium-Sensing Receptor Antagonists http://www.medworm.com/index.php?rid=3275250&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901811v%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3275250 Tue, 16 Feb 2010 13:33:49 +0100 3275250 Cloning, Characterization, and Inhibition Studies of a β-Carbonic Anhydrase from Brucella suis http://www.medworm.com/index.php?rid=3275251&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901855h%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3275251 Tue, 16 Feb 2010 13:33:33 +0100 3275251 Direct Determination of the Insulin−Insulin Receptor Interface Using Transferred Cross-Saturation Experiments http://www.medworm.com/index.php?rid=3275252&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901099v%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3275252 Tue, 16 Feb 2010 13:33:31 +0100 3275252 Synthesis and Biological Evaluation of Botulinum Neurotoxin A Protease Inhibitors http://www.medworm.com/index.php?rid=3275253&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901852f%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3275253 Mon, 15 Feb 2010 14:23:30 +0100 3275253 Leech-Derived Thrombin Inhibitors: From Structures to Mechanisms to Clinical Applications http://www.medworm.com/index.php?rid=3275254&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901743x%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3275254 Mon, 15 Feb 2010 13:52:02 +0100 3275254 Structure-Based Design, Synthesis, and Biological Studies of New Anticancer Norindenoisoquinoline Topoisomerase I Inhibitors http://www.medworm.com/index.php?rid=3275255&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901649x%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3275255 Mon, 15 Feb 2010 13:51:05 +0100 3275255 Synthesis and Evaluation of a Set of 4-Phenylpiperidines and 4-Phenylpiperazines as D2 Receptor Ligands and the Discovery of the Dopaminergic Stabilizer 4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine (Huntexil, Pridopidine, ACR16) http://www.medworm.com/index.php?rid=3275256&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901689v%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3275256 Mon, 15 Feb 2010 13:50:35 +0100 3275256 Discovery of 4-Amino-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamides As Selective, Orally Active Inhibitors of Protein Kinase B (Akt) http://www.medworm.com/index.php?rid=3269208&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901788j%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3269208 Fri, 12 Feb 2010 19:18:04 +0100 3269208 Small Molecule Inhibitors of the Neuropilin-1 Vascular Endothelial Growth Factor A (VEGF-A) Interaction http://www.medworm.com/index.php?rid=3269209&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901755g%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3269209 Fri, 12 Feb 2010 19:16:37 +0100 3269209 Novel Irreversible Epidermal Growth Factor Receptor Inhibitors by Chemical Modulation of the Cysteine-Trap Portion http://www.medworm.com/index.php?rid=3269210&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901558p%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3269210 Fri, 12 Feb 2010 19:16:36 +0100 3269210 Erratum: Corrections to Discovery of Leukotriene A4 Hydrolase Inhibitors Using Metabolomics Biased Fragment Crystallography http://www.medworm.com/index.php?rid=3269211&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm100015w%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3269211 Fri, 12 Feb 2010 19:16:31 +0100 3269211 Synthesis and Uptake of Fluorescence-Labeled Combi-molecules by P-Glycoprotein-Proficient and -Deficient Uterine Sarcoma Cells MES-SA and MES-SA/DX5 http://www.medworm.com/index.php?rid=3266189&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm9016043%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3266189 Fri, 12 Feb 2010 14:56:11 +0100 3266189 N-Heterocyclic Carbene-Amine Pt(II) Complexes, a New Chemical Space for the Development of Platinum-Based Anticancer Drugs http://www.medworm.com/index.php?rid=3266190&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901693m%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3266190 Thu, 11 Feb 2010 19:40:55 +0100 3266190 BRAF Inhibitors Based on an Imidazo[4,5]pyridin-2-one Scaffold and a Meta Substituted Middle Ring http://www.medworm.com/index.php?rid=3266191&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901509a%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3266191 Thu, 11 Feb 2010 18:13:24 +0100 3266191 Highly Potent First Examples of Dual Aromatase−Steroid Sulfatase Inhibitors based on a Biphenyl Template† http://www.medworm.com/index.php?rid=3266192&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901705h%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3266192 Thu, 11 Feb 2010 18:13:18 +0100 3266192 5-Amino-2-Aroylquinolines as Highly Potent Tubulin Polymerization Inhibitors http://www.medworm.com/index.php?rid=3266193&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm900685y%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3266193 Thu, 11 Feb 2010 18:13:17 +0100 3266193 Antitumor Agents. 272. Structure−Activity Relationships and In Vivo Selective Anti-Breast Cancer Activity of Novel Neo-tanshinlactone Analogues http://www.medworm.com/index.php?rid=3266194&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm1000858%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3266194 Thu, 11 Feb 2010 18:11:51 +0100 3266194 Enhancement of Hydrophobic Interactions and Hydrogen Bond Strength by Cooperativity: Synthesis, Modeling, and Molecular Dynamics Simulations of a Congeneric Series of Thrombin Inhibitors http://www.medworm.com/index.php?rid=3262039&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm9016416%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3262039 Thu, 11 Feb 2010 16:05:30 +0100 3262039 Development of Potent and Selective Inhibitors of ecto-5′-Nucleotidase Based on an Anthraquinone Scaffold http://www.medworm.com/index.php?rid=3262040&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901851t%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3262040 Wed, 10 Feb 2010 18:04:09 +0100 3262040 Toward Biophysical Probes for the 5-HT3 Receptor: Structure−Activity Relationship Study of Granisetron Derivatives http://www.medworm.com/index.php?rid=3262041&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901827x%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3262041 Wed, 10 Feb 2010 18:03:01 +0100 3262041 Discovery of 4-(4-(2-((5-Hydroxy-1,2,3,4-tetrahydronaphthalen-2-yl)(propyl)amino)ethyl)piperazin-1-yl)quinolin-8-ol and Its Analogues as Highly Potent Dopamine D2/D3 Agonists and as Iron Chelator: In Vivo Activity Indicates Potential Application in Symptomatic and Neuroprotective Therapy for Parkinson’s Disease http://www.medworm.com/index.php?rid=3262042&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901618d%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3262042 Wed, 10 Feb 2010 18:02:25 +0100 3262042 The Amino-Terminus of Angiotensin II Contacts Several Ectodomains of the Angiotensin II Receptor AT1 http://www.medworm.com/index.php?rid=3262043&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm9015747%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3262043 Wed, 10 Feb 2010 18:01:27 +0100 3262043 Small Molecule JNK (c-Jun N-Terminal Kinase) Inhibitors http://www.medworm.com/index.php?rid=3262044&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm9003279%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3262044 Wed, 10 Feb 2010 18:00:23 +0100 3262044 Design, Synthesis, and Evaluation of 2-Methyl- and 2-Amino-N-aryl-4,5-dihydrothiazolo[4,5-h]quinazolin-8-amines as Ring-Constrained 2-Anilino-4-(thiazol-5-yl)pyrimidine Cyclin-Dependent Kinase Inhibitors http://www.medworm.com/index.php?rid=3258035&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901660c%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3258035 Wed, 10 Feb 2010 13:48:48 +0100 3258035 Erratum: Corrections to Heat Shock Protein 90: Inhibitors in Clinical Trials http://www.medworm.com/index.php?rid=3258036&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm100114u%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3258036 Wed, 10 Feb 2010 13:04:23 +0100 3258036 Biological and Biophysical Properties of the Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid Are Affected by the Presence of Short Alkyl Groups on the Phenyl Ring http://www.medworm.com/index.php?rid=3258037&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901561u%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3258037 Tue, 09 Feb 2010 16:30:51 +0100 3258037 Synthesis and Evaluation of Paracetamol Esters As Novel Fatty Acid Amide Hydrolase Inhibitors http://www.medworm.com/index.php?rid=3253777&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901891p%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3253777 Tue, 09 Feb 2010 13:24:15 +0100 3253777 Discovery of 7-(4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyheptanamide (CUDC-101) as a Potent Multi-Acting HDAC, EGFR, and HER2 Inhibitor for the Treatment of Cancer http://www.medworm.com/index.php?rid=3253778&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901453q%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3253778 Tue, 09 Feb 2010 13:23:16 +0100 3253778 Discovery of 1-[3-(4-Bromo-2-methyl-2H-pyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea (Nelotanserin) and Related 5-Hydroxytryptamine2A Inverse Agonists for the Treatment of Insomnia http://www.medworm.com/index.php?rid=3253779&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm9007328%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3253779 Tue, 09 Feb 2010 13:23:10 +0100 3253779 Identification of Potent Pyrazolo[4,3-h]quinazoline-3-carboxamides as Multi-Cyclin-Dependent Kinase Inhibitors† http://www.medworm.com/index.php?rid=3253780&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901710h%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3253780 Mon, 08 Feb 2010 16:50:45 +0100 3253780 Piperazinyl Glutamate Pyridines as Potent Orally Bioavailable P2Y12 Antagonists for Inhibition of Platelet Aggregation http://www.medworm.com/index.php?rid=3253781&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901518t%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3253781 Mon, 08 Feb 2010 16:49:35 +0100 3253781 Incorporation of Fluorinated Phenylalanine Generates Highly Specific Inhibitor of Proteasome’s Chymotrypsin-like Sites http://www.medworm.com/index.php?rid=3243016&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm9015685%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3243016 Thu, 04 Feb 2010 22:08:22 +0100 3243016 Michael Acceptor Based Antiplasmodial and Antitrypanosomal Cysteine Protease Inhibitors with Unusual Amino Acids http://www.medworm.com/index.php?rid=3238782&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm900946n%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3238782 Thu, 04 Feb 2010 15:44:25 +0100 3238782 New Substructure Filters for Removal of Pan Assay Interference Compounds (PAINS) from Screening Libraries and for Their Exclusion in Bioassays http://www.medworm.com/index.php?rid=3238783&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901137j%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3238783 Thu, 04 Feb 2010 15:43:56 +0100 3238783 Photooxidation and Phototoxicity of π-Extended Squaraines http://www.medworm.com/index.php?rid=3238784&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901727j%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3238784 Thu, 04 Feb 2010 15:43:54 +0100 3238784 New Benzophenone-Derived Bisphosphonium Salts as Leishmanicidal Leads Targeting Mitochondria through Inhibition of Respiratory Complex II http://www.medworm.com/index.php?rid=3234977&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901677h%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3234977 Wed, 03 Feb 2010 14:02:34 +0100 3234977 Structure of Human G Protein-Coupled Receptor Kinase 2 in Complex with the Kinase Inhibitor Balanol http://www.medworm.com/index.php?rid=3234978&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm9017515%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3234978 Wed, 03 Feb 2010 13:53:20 +0100 3234978 Synthesis and Biological Evaluation of Polysulfated Oligosaccharide Glycosides as Inhibitors of Angiogenesis and Tumor Growth http://www.medworm.com/index.php?rid=3234979&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901449m%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3234979 Wed, 03 Feb 2010 13:32:22 +0100 3234979 Design and Synthesis of Potent and Selective BACE-1 Inhibitors http://www.medworm.com/index.php?rid=3234980&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901168f%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3234980 Wed, 03 Feb 2010 13:30:30 +0100 3234980 Identification and Characterization of 4-Chloro-N-(2-{[5-trifluoromethyl)-2-pyridyl]sulfonyl}ethyl)benzamide (GSK3787), a Selective and Irreversible Peroxisome Proliferator-Activated Receptor δ (PPARδ) Antagonist http://www.medworm.com/index.php?rid=3234981&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm900464j%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3234981 Wed, 03 Feb 2010 13:30:29 +0100 3234981 Structure Based Drug Design: Development of Potent and Selective Factor IXa (FIXa) Inhibitors http://www.medworm.com/index.php?rid=3230664&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901476x%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3230664 Tue, 02 Feb 2010 16:08:55 +0100 3230664 1-(Indolin-1-yl)-1-phenyl-3-propan-2-olamines as Potent and Selective Norepinephrine Reuptake Inhibitors http://www.medworm.com/index.php?rid=3230665&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901559e%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3230665 Tue, 02 Feb 2010 15:35:44 +0100 3230665 Studies of Benzothiophene Template as Potent Factor IXa (FIXa) Inhibitors in Thrombosis http://www.medworm.com/index.php?rid=3230666&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901475e%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3230666 Tue, 02 Feb 2010 15:35:39 +0100 3230666 Discovery of Novel Fibroblast Growth Factor Receptor 1 Kinase Inhibitors by Structure-Based Virtual Screening http://www.medworm.com/index.php?rid=3230667&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901386e%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3230667 Tue, 02 Feb 2010 15:32:45 +0100 3230667 Engineering Galanin Analogues That Discriminate between GalR1 and GalR2 Receptor Subtypes and Exhibit Anticonvulsant Activity following Systemic Delivery http://www.medworm.com/index.php?rid=3227055&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm9018349%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3227055 Mon, 01 Feb 2010 16:48:28 +0100 3227055 Insight into Binding of Phosphodiesterase-9A Selective Inhibitors by Crystal Structures and Mutagenesis http://www.medworm.com/index.php?rid=3227056&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901519f%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3227056 Mon, 01 Feb 2010 16:44:27 +0100 3227056 Synthesis, Biological Evaluation, and Molecular Modeling of 1-Benzyl-1H-imidazoles as Selective Inhibitors of Aldosterone Synthase (CYP11B2) http://www.medworm.com/index.php?rid=3227057&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901356d%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3227057 Mon, 01 Feb 2010 16:38:38 +0100 3227057 New Structures and Bioactivity Properties of Jasplakinolide (Jaspamide) Analogues from Marine Sponges http://www.medworm.com/index.php?rid=3227058&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm9013554%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3227058 Mon, 01 Feb 2010 16:37:15 +0100 3227058 Evolving Carbapenemases: Can Medicinal Chemists Advance One Step Ahead of the Coming Storm? http://www.medworm.com/index.php?rid=3227059&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm9012938%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3227059 Mon, 01 Feb 2010 16:21:21 +0100 3227059 A Novel Cationic Lipophosphoramide with Diunsaturated Lipid Chains: Synthesis, Physicochemical Properties, and Transfection Activities http://www.medworm.com/index.php?rid=3222691&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm900897a%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3222691 Fri, 29 Jan 2010 19:52:31 +0100 3222691 5-Modified-2′-dU and 2′-dC as Mutagenic Anti HIV-1 Proliferation Agents: Synthesis and Activity http://www.medworm.com/index.php?rid=3219651&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901758f%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3219651 Fri, 29 Jan 2010 13:57:51 +0100 3219651 Studies of the Synthesis of All Stereoisomers of MG-132 Proteasome Inhibitors in the Tumor Targeting Approach http://www.medworm.com/index.php?rid=3219652&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901619n%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3219652 Fri, 29 Jan 2010 13:56:17 +0100 3219652 Synthesis of New Thienyl Ring Containing HIV-1 Protease Inhibitors: Promising Preliminary Pharmacological Evaluation against Recombinant HIV-1 Proteases§ http://www.medworm.com/index.php?rid=3215614&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm900846f%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3215614 Thu, 28 Jan 2010 16:04:23 +0100 3215614 New Fluorinated 1,2,4-Benzothiadiazine 1,1-Dioxides: Discovery of an Orally Active Cognitive Enhancer Acting through Potentiation of the 2-Amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic Acid Receptors http://www.medworm.com/index.php?rid=3215615&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901495t%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3215615 Thu, 28 Jan 2010 16:02:33 +0100 3215615 Antisense Oligonucleotides Containing Conformationally Constrained 2′,4′-(N-Methoxy)aminomethylene and 2′,4′-Aminooxymethylene and 2′-O,4′-C-Aminomethylene Bridged Nucleoside Analogues Show Improved Potency in Animal Models http://www.medworm.com/index.php?rid=3215616&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm9013295%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3215616 Thu, 28 Jan 2010 16:01:41 +0100 3215616 Novel Inhibitors of Dengue Virus Methyltransferase: Discovery by in Vitro-Driven Virtual Screening on a Desktop Computer Grid http://www.medworm.com/index.php?rid=3215617&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm900776m%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3215617 Thu, 28 Jan 2010 15:58:34 +0100 3215617 Nitric Oxide Donors or Nitrite Counteract Copper-[dithiocarbamate]2-Mediated Tumor Cell Death and Inducible Nitric Oxide Synthase Down-Regulation: Possible Role of a Nitrosyl-Copper [Dithiocarbamate]2 Complex http://www.medworm.com/index.php?rid=3215618&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901314r%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3215618 Thu, 28 Jan 2010 15:57:36 +0100 3215618 Structure−Activity Relationships Studies in a Series of N,N-Bis(alkanol)amine Aryl Esters as P-Glycoprotein (Pgp) Dependent Multidrug Resistance (MDR) Inhibitors† http://www.medworm.com/index.php?rid=3211444&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm9016174%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3211444 Wed, 27 Jan 2010 14:16:44 +0100 3211444 Subtlety of the Structure−Affinity and Structure−Efficacy Relationships around a Nonpeptide Oxytocin Receptor Agonist http://www.medworm.com/index.php?rid=3211445&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901084f%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3211445 Wed, 27 Jan 2010 13:24:34 +0100 3211445 Two-Step Synthesis of Galactosylated Human Serum Albumin as a Targeted Optical Imaging Agent for Peritoneal Carcinomatosis http://www.medworm.com/index.php?rid=3211446&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901228u%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3211446 Tue, 26 Jan 2010 19:41:04 +0100 3211446 Synthesis and Preclinical Evaluations of 2-(2-Fluorophenyl)-6,7-methylenedioxyquinolin-4-one Monosodium Phosphate (CHM-1−P-Na) as a Potent Antitumor Agent http://www.medworm.com/index.php?rid=3211447&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901292j%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3211447 Tue, 26 Jan 2010 18:22:18 +0100 3211447 Current and Future Medical Approaches To Combat the Anthrax Threat http://www.medworm.com/index.php?rid=3207702&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901024b%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3207702 Tue, 26 Jan 2010 14:09:01 +0100 3207702 Discovery and Clinical Evaluation of 1-{N-[2-(Amidinoaminooxy)ethyl]amino}carbonylmethyl-6-methyl-3-[2,2-difluoro-2-phenylethylamino]pyrazinone (RWJ-671818), a Thrombin Inhibitor with an Oxyguanidine P1 Motif http://www.medworm.com/index.php?rid=3207703&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901802n%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3207703 Tue, 26 Jan 2010 13:23:22 +0100 3207703 Characterization of Tunable Piperidine and Piperazine Carbamates as Inhibitors of Endocannabinoid Hydrolases http://www.medworm.com/index.php?rid=3207704&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm9016976%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3207704 Mon, 25 Jan 2010 19:25:03 +0100 3207704 Discovery and Optimization of Novel 3-Piperazinylcoumarin Antagonist of Chemokine-like Factor 1 with Oral Antiasthma Activity in Mice http://www.medworm.com/index.php?rid=3204265&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901652p%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3204265 Mon, 25 Jan 2010 14:29:48 +0100 3204265 Exploring Epidermal Growth Factor Receptor (EGFR) Inhibitor Features: The Role of Fused Dioxygenated Rings on the Quinazoline Scaffold http://www.medworm.com/index.php?rid=3199941&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901338g%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3199941 Fri, 22 Jan 2010 20:22:21 +0100 3199941 Structure-Based Discovery of Novel Chemotypes for Adenosine A2A Receptor Antagonists http://www.medworm.com/index.php?rid=3199942&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901647p%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3199942 Fri, 22 Jan 2010 20:20:51 +0100 3199942 Improvement of Physiochemical Properties of the Tetrahydroazepinoindole Series of Farnesoid X Receptor (FXR) Agonists: Beneficial Modulation of Lipids in Primates http://www.medworm.com/index.php?rid=3199943&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901650u%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3199943 Fri, 22 Jan 2010 20:18:30 +0100 3199943 Low Molecular Weight Antagonists of the Myelin-Associated Glycoprotein: Synthesis, Docking, and Biological Evaluation http://www.medworm.com/index.php?rid=3199944&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901517k%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3199944 Fri, 22 Jan 2010 19:10:31 +0100 3199944 Erratum: Corrections to Synthesis, Biological Evaluation, X-ray Structure, and Pharmacokinetics of Aminopyrimidine c-jun-N-terminal Kinase (JNK) Inhibitors http://www.medworm.com/index.php?rid=3199945&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm1000425%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3199945 Fri, 22 Jan 2010 18:47:19 +0100 3199945 5-OMe-UDP is a Potent and Selective P2Y6-Receptor Agonist http://www.medworm.com/index.php?rid=3199946&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901450d%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3199946 Fri, 22 Jan 2010 16:22:10 +0100 3199946 Synthesis and Structure−Activity Relationships of Dimeric Peptide Antagonists of the Human Immunoglobulin G−Human Neonatal Fc Receptor (IgG−FcRn) Interaction http://www.medworm.com/index.php?rid=3196976&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901128z%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3196976 Thu, 21 Jan 2010 20:02:10 +0100 3196976 Erratum: Corrections to Aminoimidazoles as Potent and Selective Human β-Secretase (BACE1) Inhibitors http://www.medworm.com/index.php?rid=3196977&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901921x%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3196977 Thu, 21 Jan 2010 20:00:16 +0100 3196977 Single Agents with Designed Combination Chemotherapy Potential: Synthesis and Evaluation of Substituted Pyrimido[4,5-b]indoles as Receptor Tyrosine Kinase and Thymidylate Synthase Inhibitors and as Antitumor Agents http://www.medworm.com/index.php?rid=3196978&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm9011142%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3196978 Thu, 21 Jan 2010 19:43:04 +0100 3196978 Anti-Influenza Drug Discovery: Structure−Activity Relationship and Mechanistic Insight into Novel Angelicin Derivatives http://www.medworm.com/index.php?rid=3192855&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901570x%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3192855 Thu, 21 Jan 2010 13:23:28 +0100 3192855 Nonpeptidic Tetrafluorophenoxymethyl Ketone Cruzain Inhibitors as Promising New Leads for Chagas Disease Chemotherapy http://www.medworm.com/index.php?rid=3192856&cid=s_32526_59_f&fid=32526&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fjm901633v%3Fai%3D55a%26af%3DR Journal of Medicinal Chemistry, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Journal of Medicinal Chemistry) Journal of Medicinal Chemistry journals http://www.medworm.com/rss/comments.php?id=3192856 Wed, 20 Jan 2010 16:36:30 +0100 3192856