MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Journal of Periodontal Research' source. Wed, 08 Feb 2012 12:06:25 +0100 http://www.medworm.com/index.php?rid=5667193&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01464.x Conclusion:  The results demonstrated a significant increase in the number of some specific markers of Th17 cells in patients suffering from periodontal disease in comparison with normal control subjects. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5667193 Mon, 06 Feb 2012 05:00:00 +0100 5667193 http://www.medworm.com/index.php?rid=5667192&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01463.x Conclusion:  The results from this study clearly demonstrated the sequential histological changes during periodontal tissue regeneration by hPDLSCs. Understanding of this process would potentially enable us to develop better cell‐based treatment techniques. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5667192 Mon, 06 Feb 2012 05:00:00 +0100 5667192 http://www.medworm.com/index.php?rid=5667191&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01466.x Conclusion:  We show, for the first time, the presence of resistin in gingival crevicular fluid. A high resistin level in gingival crevicular fluid samples from periodontitis patients may to some extent be related to P‐LPS‐induced resistin release from neutrophils. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5667191 Wed, 01 Feb 2012 05:00:00 +0100 5667191 http://www.medworm.com/index.php?rid=5647835&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01453.x Conclusion:  In the present study, we showed that the formation of immune complex appears to be involved in the acute phase of periodontal destruction and that the biological activity of antigens is also important. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5647835 Wed, 01 Feb 2012 05:00:00 +0100 5647835 http://www.medworm.com/index.php?rid=5647836&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01452.x Conclusion:  Gram‐positive or gram‐negative PGN worked synergistically with LPS to induce bone resorption and osteoclastogenesis, possibly by co‐ordinating the effects of TLR2, NOD1, NOD2 and TLR4 signaling. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5647836 Sun, 29 Jan 2012 05:00:00 +0100 5647836 http://www.medworm.com/index.php?rid=5608874&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01462.x Conclusion:  The results of the RFA measurements of both tested devices overlap. Although both devices show excellent intra‐observer reliability, there are variations between the measurements of different examiners. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5608874 Fri, 20 Jan 2012 16:12:51 +0100 5608874 http://www.medworm.com/index.php?rid=5560209&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01461.x (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5560209 Thu, 05 Jan 2012 12:10:53 +0100 5560209 http://www.medworm.com/index.php?rid=5560208&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01460.x (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5560208 Thu, 05 Jan 2012 12:10:29 +0100 5560208 http://www.medworm.com/index.php?rid=5560205&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01455.x Conclusion: A. actinomycetemcomitans, F. nucleatum and P. gingivalis were present in significantly different quantities and proportions in subgingival plaque, according to periodontal disease status. No significant differences were identified between the subgingival microbiota of type 2 diabetes mellitus patients compared with nondiabetic subjects. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5560205 Thu, 05 Jan 2012 12:09:20 +0100 5560205 http://www.medworm.com/index.php?rid=5560207&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01458.x Conclusion:  Multiple protein components in gingival crevicular fluid were analysed at the same time using mass spectrometry, and this approach may be useful for the diagnosis of periodontal diseases. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5560207 Tue, 03 Jan 2012 05:00:00 +0100 5560207 http://www.medworm.com/index.php?rid=5560206&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01459.x Conclusion:  Individuals with Down syndrome show higher levels of some subgingival bacterial species and specific associations between certain subgingival bacterial species and loss of periodontal attachment. These findings are consistent with the notion that certain subgingival bacteria may contribute to the increased level of periodontal disease seen in Down syndrome individuals and raise the question as to the reason for increased colonization in Down syndrome. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5560206 Tue, 03 Jan 2012 05:00:00 +0100 5560206 http://www.medworm.com/index.php?rid=5524635&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01439.x Conclusion:  AMI may be reflected in PMN serine protease elastase activity in saliva, despite its strong association with periodontitis. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5524635 Mon, 19 Dec 2011 05:00:00 +0100 5524635 http://www.medworm.com/index.php?rid=5524634&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01449.x Conclusion:  Predialysis and HD are associated with a higher prevalence of severe periodontitis compared with healthy individuals and CAPD patients. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5524634 Mon, 19 Dec 2011 05:00:00 +0100 5524634 http://www.medworm.com/index.php?rid=5524633&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01454.x Conclusion:  These findings suggest that CAM administration is useful to suppress periodontal bacteria‐accelerated abdominal aortic aneurysms via MMP regulation. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5524633 Mon, 19 Dec 2011 05:00:00 +0100 5524633 http://www.medworm.com/index.php?rid=5494927&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01447.x Conclusion:  Religiosity had a protective effect against periodontitis through extrinsic and intrinsic pathways. This should be considered as part of aetiology and prognosis, in potential prevention and care of periodontitis. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5494927 Mon, 12 Dec 2011 05:00:00 +0100 5494927 http://www.medworm.com/index.php?rid=5494928&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01433.x Conclusion:  These data suggest that stabilization of β‐catenin by WNT3A inhibits BMP2‐mediated induction of cementoblast/osteoblast differentiation in SVF4 cells, although BMP2 requires endogenous Wnt/β‐catenin signaling to promote cell maturation. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5494928 Sun, 11 Dec 2011 05:00:00 +0100 5494928 http://www.medworm.com/index.php?rid=5476566&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01443.x Conclusion:  The concentrations and ratios of Ca2+ and P ions could significantly influence proliferation, differentiation and mineralization of hPDLCs. Within the range of concentrations tested, we found that the combination of 9.0 mm Ca2+ ions and 4.5 mm P ions were the optimal concentrations for proliferation, differentiation and mineralization in hPDLCs. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5476566 Mon, 05 Dec 2011 05:00:00 +0100 5476566 http://www.medworm.com/index.php?rid=5552297&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01456.x Conclusion:  Our data indicate that EMD acts as a proangiogenic factor in vitro and, as such, might contribute to periodontal tissue regeneration by stimulation of vessel formation during wound healing. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5552297 Thu, 01 Dec 2011 05:00:00 +0100 5552297 http://www.medworm.com/index.php?rid=5524632&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01440.x Conclusion:  The predominant cultural subgingival flora in dogs shows great similarities with the subgingival bacteria from humans at the genus level, but distinct differences at the species level; however, a genetic relatedness could be disclosed for most strains investigated. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5524632 Thu, 01 Dec 2011 05:00:00 +0100 5524632 http://www.medworm.com/index.php?rid=5494926&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01451.x Conclusion:  The present study demonstrates, for the first time, that DNase activity is a relatively common property of bacteria associated with advanced periodontal disease. Further work is required to determine the importance of this bacterial DNase activity in the pathogenesis of periodontitis. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5494926 Thu, 01 Dec 2011 05:00:00 +0100 5494926 http://www.medworm.com/index.php?rid=5476565&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01438.x Conclusion:  Binary applications of hOP‐1and hTGF‐β3 in Matrigel® matrix in Class II furcation defects of P. ursinus induced substantial periodontal tissue regeneration, which was tempered, however, by the anatomy of the furcation defect model, which does not allow for the rapid growth and expansion of the synergistic induction of bone formation, particularly when additionally treated with responding myoblastic stem cells. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5476565 Thu, 01 Dec 2011 05:00:00 +0100 5476565 http://www.medworm.com/index.php?rid=5457654&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01448.x Conclusion:  The results of present study suggest that bleeding on probing was the only different periodontal parameter between the AS and the control group, and the periodontal status of patients with AS may be affected by IL‐6 levels. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5457654 Thu, 01 Dec 2011 05:00:00 +0100 5457654 http://www.medworm.com/index.php?rid=5457657&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01445.x Conclusion:  These findings suggest that the chemokine MIP‐1α may aid in identifying periodontitis. Future longitudinal studies are warranted to determine whether this biomarker can help in ascertaining the progression of bone loss in subjects with periodontal disease. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5457657 Tue, 29 Nov 2011 05:00:00 +0100 5457657 http://www.medworm.com/index.php?rid=5457656&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01444.x Conclusion:  The data indicate that long‐lived collagen fibers do not exist in the soft tissues of the periodontium, and are probably not responsible for relapse. The differences in collagen half‐life might be caused by local variations in compressive strain induced by normal function. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5457656 Tue, 29 Nov 2011 05:00:00 +0100 5457656 http://www.medworm.com/index.php?rid=5457655&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01446.x Conclusion:  The results of this study indicate that PRF can improve clinical parameters associated with human intrabony periodontal defects, and BPBM has the ability to augment the effects of PRF in reducing pocket depth, improving clinical attachment levels and promoting defect fill. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5457655 Tue, 29 Nov 2011 05:00:00 +0100 5457655 http://www.medworm.com/index.php?rid=5449781&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01426.x Conclusion:  The polymorphisms of −2518MCP‐1 may play an important role in determining generalized aggressive periodontitis susceptibility in this cohort of Chinese women. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5449781 Mon, 28 Nov 2011 04:52:18 +0100 5449781 http://www.medworm.com/index.php?rid=5449782&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01437.x This article critically reviews the current understanding of genetic polymorphism studies in periodontitis, then summarizes the research status of Fcγ receptor polymorphisms and periodontitis and also of other genes involved in the regulatory network of Fcγ receptors, with special reference to their anticipated biological roles. Moreover, some possible future research directions in the related area are discussed. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5449782 Sun, 27 Nov 2011 05:00:00 +0100 5449782 http://www.medworm.com/index.php?rid=5431695&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01441.x Conclusion:  These data demonstrate that oral infection with P. gingivalis induces alterations in systemic cytokine production. These cytokines could play roles in the development not only of periodontitis but also of atherosclerosis. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5431695 Tue, 22 Nov 2011 04:44:37 +0100 5431695 http://www.medworm.com/index.php?rid=5431696&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01428.x Conclusion:  Osteoactivin demonstrates a significant potential to support bone regeneration/formation. Studies using discriminating large animal models are necessary to explore clinical application for periodontal and craniofacial indications. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5431696 Sun, 20 Nov 2011 05:00:00 +0100 5431696 http://www.medworm.com/index.php?rid=5422128&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01424.x Conclusion:  These results confirm that the initiation of experimental periodontal disease is associated with reduction in the expression of claudin‐1 gene and protein. This decreased level of a critical tight junction protein may result in the disruption of barrier function and may play an important role in the initiation of periodontal disease. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5422128 Sat, 19 Nov 2011 04:38:58 +0100 5422128 http://www.medworm.com/index.php?rid=5422129&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01442.x Conclusion:  At less‐than‐pathological concentrations in gingival crevicular fluid, H2S induces apoptosis in osteoblasts. The molecular mechanisms underlying the apoptotic process include p53, a mitochondrial pathway and caspase‐8 activation. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5422129 Fri, 18 Nov 2011 05:00:00 +0100 5422129 http://www.medworm.com/index.php?rid=5422130&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01435.x Conclusion:  The data suggest that the CBD may promote fibrotic gingival enlargement by increasing gingival fibroblast production of transforming growth factor β and fibronectin, while decreasing MMP production and activity. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5422130 Thu, 17 Nov 2011 05:00:00 +0100 5422130 http://www.medworm.com/index.php?rid=5386613&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01436.x Conclusion:  LL‐37 strongly attenuates lipopolysaccharide‐induced cytokine and chemokine expression and, in high concentrations, reduces cell proliferation through inhibition of DNA synthesis and by promoting apoptosis in human periodontal ligament cells. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5386613 Thu, 10 Nov 2011 05:05:03 +0100 5386613 http://www.medworm.com/index.php?rid=5386614&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01430.x Conclusion:  These results suggest that APM is more effective than AsANa in terms of intake, collagen synthesis, decreasing cell damage and inhibiting interleukin‐8 expression in human gingival fibroblasts. This suggests that local application of APM can help to prevent periodontal disease. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5386614 Wed, 09 Nov 2011 05:00:00 +0100 5386614 http://www.medworm.com/index.php?rid=5386616&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01418.x Hirsch R, Deng H, Laohachai MN. Azithromycin in periodontal treatment: more than an antibiotic. J Periodont Res 2011.doi: 10.1111/j.1600‐0765.2011.01418.x.©2011 John Wiley & Sons A/SAzithromycin is a macrolide antibiotic used extensively in medicine for the treatment of a wide range of infections such as upper respiratory tract infections, middle ear infections, sexually transmitted infections and trachoma. It is also effective against the most common periodontopathogens. The versatility of the macrolides extends beyond their antibiotic properties as a result of their well‐documented immune‐modulating/anti‐inflammatory effects. Macrolides, including azithromycin, are therefore used to treat diseases not associated with bacteria, such as severe asthma, chronic obstructive pulmo... Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5386616 Fri, 04 Nov 2011 04:00:00 +0100 5386616 http://www.medworm.com/index.php?rid=5386615&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01431.x Conclusion:  Patients with IBD have higher prevalence, severity and extent of periodontitis compared with those having no IBD. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5386615 Fri, 04 Nov 2011 04:00:00 +0100 5386615 http://www.medworm.com/index.php?rid=5360419&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01425.x Conclusion:  The reduced concentrations of SLPI and ELAFIN may contribute to the loss of host protective capacity and increase susceptibility to breakdown from chronic infection. The work of this investigation may aid in finding diagnostic and prognostic markers in periodontal health and disease and may also help in finding pharmacological targets directed against periodontal inflammation. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5360419 Mon, 31 Oct 2011 02:42:10 +0100 5360419 http://www.medworm.com/index.php?rid=5386617&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01427.x Conclusion: P. gingivalis supernatant increased the migratory ability of monocytes, in part, by increasing activation and expression of MMP‐9. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5386617 Sun, 30 Oct 2011 04:00:00 +0100 5386617 http://www.medworm.com/index.php?rid=5360420&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01429.x Conclusion:  Firstly, the data presented herein provide the proteome of gingival crevicular fluid from periodontally healthy sites through establishment of innovative analytical approaches for effective analysis of gingival crevicular fluid from periopapers both at the level of complete elusion and with removal of abundant albumin, which restricts identification of low‐abundant proteins. Secondly, it adds significantly to the knowledge of gingival crevicular fluid composition and highlights new groups of proteins specific to the gingival crevicular fluid microenvironment. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5360420 Wed, 26 Oct 2011 04:00:00 +0100 5360420 http://www.medworm.com/index.php?rid=5335740&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01434.x (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5335740 Sat, 22 Oct 2011 03:47:06 +0100 5335740 http://www.medworm.com/index.php?rid=5335739&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01423.x Conclusion:  The study has identified several mechanoresponsive adhesion‐related genes, and shown that onset of mechanical stress was followed by a transient reduction in overall cellular activity, including the expression of two apoptosis ‘executioner’ caspases. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5335739 Sat, 22 Oct 2011 03:46:32 +0100 5335739 http://www.medworm.com/index.php?rid=5285649&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01422.x Conclusion:  Although additional studies are required to dissect the molecular mechanism of action, our results suggest that daidzein could be a promising agent for treating inflammatory periodontal disease. Further research in animal models of periodontitis is necessary to better evaluate the potential of daidzein as a novel therapeutic agent to treat periodontal disease. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5285649 Wed, 05 Oct 2011 04:00:00 +0100 5285649 http://www.medworm.com/index.php?rid=5314505&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01406.x Conclusion:  The present study showed that the oral administration of thymoquinone diminishes alveolar bone resorption in a rat periodontitis model. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5314505 Sat, 01 Oct 2011 04:00:00 +0100 5314505 http://www.medworm.com/index.php?rid=5285648&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01419.x Conclusion:  These results suggest that ZFH/Chd3 might play an important role in tooth root development and subsequent cementogenesis. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5285648 Sat, 01 Oct 2011 04:00:00 +0100 5285648 http://www.medworm.com/index.php?rid=5273792&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01421.x Conclusion:  These results suggest that ANE exposure interfered with the differentiation of dendritic cells from monocytes. Moreover, the functionality of mature monocyte‐derived dendritic cells was attenuated in the presence of ANE. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5273792 Sat, 01 Oct 2011 04:00:00 +0100 5273792 http://www.medworm.com/index.php?rid=5273793&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01416.x Conclusion:  In this sample of female periodontitis patients, a broad range of intra‐individual and interindividual aMMP‐8 values was found. Although the explained variance was rather weak, a statistically significant relationship between aMMP‐8 and pocket depth was proven. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5273793 Fri, 30 Sep 2011 04:00:00 +0100 5273793 http://www.medworm.com/index.php?rid=5260714&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01420.x Conclusion:  Regular interdental cleaning was associated with better oral hygiene outcomes, such as dental plaque and gingivitis, although there was no significant association between regular interdental cleaning and clinical attachment loss. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5260714 Thu, 29 Sep 2011 03:44:26 +0100 5260714 http://www.medworm.com/index.php?rid=5260716&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01415.x Conclusion:  These results suggest that PHD inhibitors enhance the production of VEGF in periodontal fibroblasts, even in the presence of proinflammatory IL‐1. The data further suggest that PHD inhibitors do not provoke a significant proinflammatory or anti‐inflammatory response in this in vitro setting. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5260716 Wed, 28 Sep 2011 04:00:00 +0100 5260716 http://www.medworm.com/index.php?rid=5260715&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01417.x Conclusion A rare haplotype of the NR1I2 (PXR) locus was associated with the individual susceptibility for chronic periodontitis in a German cohort. As a result of the borderline significance and the small effect size the present results need further confirmation (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5260715 Wed, 28 Sep 2011 04:00:00 +0100 5260715 http://www.medworm.com/index.php?rid=5237382&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01414.x Conclusion:  Topical application of poly(P) may induce connective tissue remodeling, contributing to improvement of inflamed gingiva in rats. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5237382 Wed, 21 Sep 2011 20:29:52 +0100 5237382 http://www.medworm.com/index.php?rid=5208738&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01411.x Conclusion:  The higher expression levels of FcγRIIb in subjects with the FcγRIIB‐nt645+25AA genotype may induce a lower level of production of IgG against P. gingivalis and therefore more severe periodontitis. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5208738 Mon, 12 Sep 2011 20:28:46 +0100 5208738 http://www.medworm.com/index.php?rid=5208739&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01402.x Conclusion:  This proof‐of‐principle study suggests that cellular therapy, in combination with a collagen sponge, promoted periodontal regeneration in experimental intrabony periodontal defects. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5208739 Mon, 12 Sep 2011 04:00:00 +0100 5208739 http://www.medworm.com/index.php?rid=5196417&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01404.x Conclusion:  The results suggest that IM reverses the TNF‐α‐induced disruption of the gingival epithelial barrier by regulating E‐cadherin and claudin‐1. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5196417 Tue, 06 Sep 2011 22:18:33 +0100 5196417 http://www.medworm.com/index.php?rid=5196420&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01408.x Conclusion:  The results obtained in the present study show that P. gingivalis extract induces TNF‐α and IL‐6 in an in vitro liver model and that macrophage‐derived TNF‐α mediates the induction of TNF‐α in hepatocytes. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5196420 Sun, 04 Sep 2011 23:00:00 +0100 5196420 http://www.medworm.com/index.php?rid=5196419&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01409.x Conclusion:  There is a defined order in bacterial species succession in early supragingival and subgingival biofilm redevelopment after professional cleaning. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5196419 Sun, 04 Sep 2011 23:00:00 +0100 5196419 http://www.medworm.com/index.php?rid=5196418&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01413.x Conclusion:  This study shows that cytomegalovirus and human herpesvirus 7 can be present at periodontitis‐affected sites but are uncommon at healthy periodontal sites. Moreover, our data suggest that cytomegalovirus can be related to an inflammatory infiltrate with predominance of CD3+ T cells, whereas human herpesvirus 7 can be associated with an infiltrate with predominance of T‐CD4+ cells. However, further studies are necessary to support this hypothesis. Herpesviruses could play a role in human chronic periodontitis by modulation of the T cell response. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5196418 Sun, 04 Sep 2011 23:00:00 +0100 5196418 http://www.medworm.com/index.php?rid=5170357&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01412.x Conclusion:  The data presented here confirm that TGF‐β1 expression is related to the molecular events associated with CsA‐induced gingival overgrowth and suggest that Smad7 overexpression is effective in blocking these events, including proliferation, type I collagen synthesis and MMP‐2 activity. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5170357 Mon, 29 Aug 2011 13:04:15 +0100 5170357 http://www.medworm.com/index.php?rid=5170358&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01410.x Conclusion:  The urpA gene is a novel gene required for natural competence in A. actinomycetemcomitans and does not exhibit significant homology with any natural competence genes previously identified in other bacterial species. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5170358 Sat, 27 Aug 2011 23:00:00 +0100 5170358 http://www.medworm.com/index.php?rid=5161754&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01407.x Conclusion:  Our results raise the possibility that HGF signaling controls root formation via the development of HERS. This study is the first to show that HGF is one of the stimulators of root development. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5161754 Sat, 27 Aug 2011 14:31:58 +0100 5161754 http://www.medworm.com/index.php?rid=5143786&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01405.x Conclusion:  These data suggest that the expression of these TLRs 2, 3, 4 and 9 in gingival tissue is higher in individuals with diabetes because its inflammatory reaction is exacerbated. Additionally, the expression of these TLRS is positively regulated with the severity of periodontal disease. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5143786 Sat, 20 Aug 2011 15:16:07 +0100 5143786 http://www.medworm.com/index.php?rid=5143788&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01396.x Conclusion:  Based on the results from this study, the effect of reduced functional loads for a prolonged time could differentially affect morphology, mechanical properties and mineral variations of the local load‐bearing sites in the bone–periodontal ligament–cementum complex. These observed local changes in turn could help to explain the overall biomechanical function and adaptations of the tooth–bone joint. From a clinical translation perspective, our study provides an insight into modulation of load on the complex for improved tooth function during periodontal disease and/or orthodontic and prosthodontic treatments. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5143788 Tue, 16 Aug 2011 23:00:00 +0100 5143788 http://www.medworm.com/index.php?rid=5143787&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01401.x Conclusion:  Our data suggest that P. gingivalis HmuY may be considered an immunogenic protein associated with host–pathogen interactions. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5143787 Tue, 16 Aug 2011 23:00:00 +0100 5143787 http://www.medworm.com/index.php?rid=5088480&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01403.x Conclusion:  Both PMSRP and FMSRP promoted benefits in clinical parameters and showed a similar modulation of cytokines and osteoclastogenesis‐related factors at 12 mo in type 2 diabetic subjects. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5088480 Sun, 31 Jul 2011 23:00:00 +0100 5088480 http://www.medworm.com/index.php?rid=5079492&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01400.x Conclusion:  The quantity of osteoclastic cells and the increased expression of proteolytic enzymes suggest that 8 months after grafting, inorganic bovine bone is slowly resorbing and is the site of important remodeling of the newly formed bone by means of resorption and synthesis. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5079492 Sun, 31 Jul 2011 23:00:00 +0100 5079492 http://www.medworm.com/index.php?rid=5079493&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01398.x Conclusion:  This cross‐sectional study showed that P. nigrescens and P. gingivalis were significantly associated with increased cIMA values. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5079493 Tue, 26 Jul 2011 23:00:00 +0100 5079493 http://www.medworm.com/index.php?rid=5052792&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01393.x Conclusion:  Employing tissue‐engineering techniques with dermal and epidermal cells from the gingiva, a multilayered oral mucosa was generated and characterized with respect to biocompatibility for Matriderm®. The results indicate that Matriderm® is suitable for the ex vivo growth of gingival tissue cells and is a useful scaffold with possible applications in periodontal therapy. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5052792 Sat, 23 Jul 2011 16:00:57 +0100 5052792 http://www.medworm.com/index.php?rid=5052794&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01397.x Conclusion:  This study identified several force‐sensing genes implicated in the apoptotic pathway in periodontal ligament cells and should facilitate future studies on force‐driven apoptosis by providing putative target genes. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5052794 Wed, 20 Jul 2011 23:00:00 +0100 5052794 http://www.medworm.com/index.php?rid=5052793&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01399.x Conclusion:  The existing randomized controlled trials have important methodological limitations; consequently, there is insufficient evidence to support the efficacy of probiotics in treating periodontal disease. More rigorous scientific research, in accordance with existing guidelines and research recommendations of the present review, is required to examine the safety and efficacy of probiotics before they are embraced in periodontal therapy. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5052793 Wed, 20 Jul 2011 23:00:00 +0100 5052793 http://www.medworm.com/index.php?rid=5039593&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01395.x Conclusion:  The present study indicated that periodontal treatment played an important role and tongue cleaning contributed to a lesser extent to reduction in oral malodor in periodontitis patients. In contrast, tongue cleaning alone can be the primary approach to reduce oral malodor in gingivitis patients. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5039593 Wed, 20 Jul 2011 15:27:58 +0100 5039593 http://www.medworm.com/index.php?rid=5039594&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01351.x Conclusion:  In the absence of mechanical stress, the PDL fiber system undergoes degradation concomitantly with a reduction in the periostin and CTGF levels in the PDL. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5039594 Sun, 17 Jul 2011 23:00:00 +0100 5039594 http://www.medworm.com/index.php?rid=5020749&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01394.x Conclusion:  These data suggest that SIRT1 is a potent regulator of differentiation of human periodontal ligament cells and may have clinical implications for periodontal bone regeneration. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5020749 Wed, 13 Jul 2011 16:13:11 +0100 5020749 http://www.medworm.com/index.php?rid=5020750&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01392.x Conclusion:  HDACi were found to effectively suppress bone loss in the mouse model of periodontitis. 1179.4b – the inhibitor of Class I and Class II HDACs – was more effective at suppressing bone loss than MS‐275, which targets Class I HDACs only. These compounds may therefore have the potential to be used for the management of periodontitis. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5020750 Sun, 10 Jul 2011 23:00:00 +0100 5020750 http://www.medworm.com/index.php?rid=5009950&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01391.x Conclusion:  The administration of 20 mg/kg of aminoguanidine daily in diabetic rats raised the biomechanical retention of the implants to the level observed in the healthy rat group. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5009950 Sat, 09 Jul 2011 18:39:10 +0100 5009950 http://www.medworm.com/index.php?rid=4999135&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01385.x Conclusion:  Within the limits of this pilot study, it was concluded that inoculation of P. gingivalis affected the ligature‐induced ABL model by the induction of an anti‐inflammatory and antiresorptive host response. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4999135 Wed, 06 Jul 2011 14:02:04 +0100 4999135 http://www.medworm.com/index.php?rid=5009951&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01375.x Conclusion:  Within its limits, this study demonstrated that smoking affected mRNA expression of MMPs and TIMP‐1, MMPs/TIMP‐1 ratios and relationships among MMPs in untreated chronic periodontitis and expression of MMPs in health. In the absence of smoking, chronic periodontitis affected expression of MMPs and MMPs/TIMP‐1 ratios. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=5009951 Tue, 05 Jul 2011 23:00:00 +0100 5009951 http://www.medworm.com/index.php?rid=4999137&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01383.x Conclusion:  The findings suggest that complement activation, and particularly C5a generation, may play a significant role in the development and progression of periodontitis. Blockade of the major C5a receptor, CD88, with specific inhibitors such as PMX205, may offer novel treatment options for periodontitis. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4999137 Sat, 02 Jul 2011 23:00:00 +0100 4999137 http://www.medworm.com/index.php?rid=4999136&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01386.x Conclusion:  Intermittent treatment with PTH stimulated osteoblastic differentiation in fetal rat calvaria cell cultures, and topical and intermittent administration of PTH recovered alveolar bone loss in rat experimental periodontitis. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4999136 Sat, 02 Jul 2011 23:00:00 +0100 4999136 http://www.medworm.com/index.php?rid=4970328&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01390.x Conclusion:  ErhBMP‐2/bMBCP induced significant bone formation in both calvarial and ectopic sites. Further study appears to be required to evaluate the relevance of the bMBCP carrier. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4970328 Mon, 27 Jun 2011 17:44:47 +0100 4970328 http://www.medworm.com/index.php?rid=4936968&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01387.x Conclusion:  The data generated by the use of ’omic technologies have huge potential to inform paradigm shifts in our understanding of periodontal diseases, but data management, analysis and interpretation require a thoughtful and systematic bioinformatics approach, to ensure meaningful conclusions can be made. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4936968 Wed, 15 Jun 2011 23:00:00 +0100 4936968 http://www.medworm.com/index.php?rid=4936969&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01378.x Conclusion:  This approach provides novel insight into profiles of the salivary proteome during gingival inflammation, which may contribute to improvements in diagnosis. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4936969 Mon, 13 Jun 2011 23:00:00 +0100 4936969 http://www.medworm.com/index.php?rid=4904241&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01384.x Conclusion:  Ultrasound may contribute to the reduction of the trauma‐induced inflammatory reaction through impairment of the TNF‐α signaling pathway. It is therefore suggested that ultrasound shows potential as a therapeutic tool to optimize the regenerative potential of periodontal tissues on replanted teeth. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4904241 Sun, 05 Jun 2011 23:00:00 +0100 4904241 http://www.medworm.com/index.php?rid=4936967&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01388.x Conclusion:  This pilot study provided no evidence to suggest that patients with aggressive periodontitis (not previously diagnosed with diabetes) have evidence of diabetes or altered serum levels of inflammatory mediators, lipids and adipokines. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4936967 Tue, 31 May 2011 23:00:00 +0100 4936967 http://www.medworm.com/index.php?rid=4904240&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01389.x Conclusion:  Hemin binding protein 35 appears to be an important molecule involved in recognition of the redox state of environmental conditions. In addition, TCmAb‐h13 had an inhibitory effect on heme binding to recombinant HBP35, thereby interfering with P. gingivalis growth. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4904240 Tue, 31 May 2011 23:00:00 +0100 4904240 http://www.medworm.com/index.php?rid=4895332&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01377.x Conclusion:  Within the limits of the present study, it may be suggested that an elevated salivary IL‐18 level in untreated nonsmoker chronic periodontitis patients has the potential to be a biomarker for periodontal tissue destruction. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4895332 Tue, 31 May 2011 23:00:00 +0100 4895332 http://www.medworm.com/index.php?rid=4885725&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01380.x Conclusion:  This study demonstrated that nonsurgical periodontal therapy results in a significant reduction in the serum CRP level. The effect of this outcome on systemic disease is still unknown. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4885725 Tue, 31 May 2011 23:00:00 +0100 4885725 http://www.medworm.com/index.php?rid=4885724&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01381.x Conclusion:  The present study demonstrated that both CAF + EMD and CAF + CTG procedures were similarly successful in treating Miller Class I and Class II single gingival recession defects. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4885724 Tue, 31 May 2011 23:00:00 +0100 4885724 http://www.medworm.com/index.php?rid=4864157&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01382.x Conclusion:  Human gingival epithelial cells display strong ERβ but low ERα immunoreactivity both in vivo and in culture. Estrogen attenuates gingival epithelial cell DNA synthesis at high but not low concentrations, suggesting a concentration‐dependent mechanism. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4864157 Thu, 26 May 2011 15:58:51 +0100 4864157 http://www.medworm.com/index.php?rid=4864160&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01374.x Conclusion:  Our results strongly suggest that MAPK, AP‐1 and NF‐κB mediate the IL‐1β‐stimulated synthesis of IL‐6, IL‐8, PGE2 and MMP‐1 in human periodontal ligament cells. Therefore, inhibition of activation of MAPK, AP‐1 and/or NF‐κB may lead to therapeutic effects on progression of periodontitis. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4864160 Tue, 24 May 2011 23:00:00 +0100 4864160 http://www.medworm.com/index.php?rid=4864159&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01379.x Conclusion:  Our study demonstrated the involvement of gap‐junction hemichannels, especially connexin43, in the stress‐induced ATP‐release mechanism. Furthermore, this mechanism may be regulated by the intracellular Ca2+ signaling pathway. These results suggest an important role of gap‐junction hemichannels in the function and behavior of HPDL cells. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4864159 Tue, 24 May 2011 23:00:00 +0100 4864159 http://www.medworm.com/index.php?rid=4864158&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01376.x Conclusion:  These findings suggest proliferation and/or aggregation of periodontal ligament epithelial cells, and interaction between OX6‐immunopositive cells and the periodontal ligament epithelial cells, in response to tooth movement and periodontal inflammation. This method may be a useful experimental model to elucidate the relationship between rete pegs and periodontal ligament epithelial cell clusters in inflammatory conditions. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4864158 Tue, 24 May 2011 23:00:00 +0100 4864158 http://www.medworm.com/index.php?rid=4754947&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01373.x Conclusion:  The mechanism by which S. cristatus attenuates F. nucleatum‐induced proinflammatory responses in oral epithelial cells appears to involve blockade of NF‐κB nuclear translocation at the level of IκB‐α degradation. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4754947 Wed, 27 Apr 2011 15:52:12 +0100 4754947 http://www.medworm.com/index.php?rid=4748590&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01370.x Conclusion:  Exposure to whole cigarette smoke markedly inhibits epithelial cell growth through an apoptosis/necrosis pathway that involves Bax and Bcl‐xL proteins and caspase‐3 activity. Cigarette smoke also disrupts epithelial cell migration, which may negatively affect periodontal wound healing. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4748590 Tue, 26 Apr 2011 13:59:51 +0100 4748590 http://www.medworm.com/index.php?rid=4754948&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01362.x Conclusion:  The results demonstrate that CD40L accelerates osteoclastogenesis in the presence of RANKL and LPS. The results also suggest that mCD40L on LPS‐T cells accelerates osteoclastogenesis. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4754948 Mon, 25 Apr 2011 23:00:00 +0100 4754948 http://www.medworm.com/index.php?rid=4748591&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01363.x Conclusion:  Local expression of TRPV1 and TLR4 in gingival tissues may contribute to both physiological and pathological processes in the periodontium. Our data suggest that TRPV1 and TLR4 may play a role specifically in the pathophysiology of chronic periodontitis. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4748591 Sun, 24 Apr 2011 23:00:00 +0100 4748591 http://www.medworm.com/index.php?rid=4736097&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01372.x Conclusion:  Our study showed that a blackcurrant extract and its major anthocyanins were able to inhibit the activity of host‐ and bacteria‐derived proteinases. This suggests that such natural compounds may represent promising agents for use in adjunctive treatments for periodontitis. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4736097 Fri, 22 Apr 2011 15:52:39 +0100 4736097 http://www.medworm.com/index.php?rid=4736098&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01371.x Conclusion:  Periodontal disease is a possible risk factor for preterm delivery in this population. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4736098 Tue, 19 Apr 2011 23:00:00 +0100 4736098 http://www.medworm.com/index.php?rid=4725707&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01369.x Conclusion:  The subclinical increase of IL‐6 at progesterone peak is not accompanied by clinical changes in the periodontium. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4725707 Tue, 19 Apr 2011 16:12:17 +0100 4725707 http://www.medworm.com/index.php?rid=4725709&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01365.x Conclusion:  Results from the present study suggest that serum osteocalcin was significantly associated with renal function and periodontal disease. The low systemic bone metabolism, which might be caused by low renal function, is associated with periodontal disease. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4725709 Sun, 17 Apr 2011 23:00:00 +0100 4725709 http://www.medworm.com/index.php?rid=4725708&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01368.x Conclusion:  Periodontitis was clinically related to pre‐eclampsia; however, the supposed mechanism that correlates the two diseases, i.e. a systemic inflammatory process involving cytokines TNFα and IL‐6 in the presence of periodontal disease, could not be confirmed in this study. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4725708 Sun, 17 Apr 2011 23:00:00 +0100 4725708 http://www.medworm.com/index.php?rid=4705542&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01359.x Conclusion:  Diabetes affects proteins involved in remodeling of periodontal ligament during mechanical pressure. This may delay the reconstruction and remodeling of periodontal ligament in diabetic individuals. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4705542 Tue, 12 Apr 2011 23:00:00 +0100 4705542 http://www.medworm.com/index.php?rid=4705541&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01366.x Conclusion:  Our results suggest that P. gingivalis can be detected in chorionic tissues of hospitalized high‐risk pregnant women, and that P. gingivalis lipopolysaccharide induces interleukin‐6 and interleukin‐8 production via TLR‐2 in chorion‐derived cells. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4705541 Tue, 12 Apr 2011 23:00:00 +0100 4705541 http://www.medworm.com/index.php?rid=4677667&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01350.x Conclusion:  These findings indicate that aggressive periodontitis is associated with elevated levels of plasma calprotectin and that gene polymorphisms of S100A8 may influence the susceptibility and severity of aggressive periodontitis. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4677667 Sun, 03 Apr 2011 23:00:00 +0100 4677667 http://www.medworm.com/index.php?rid=4710206&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01367.x Conclusion:  Lactate dehydrogenase may distinguish localized and generalized aggressive periodontitis. Alkaline phosphatase increases from moderate to severe states in both types of periodontitis. Aspartate aminotransferase and neutrophil elastase only increase with strong evidence of periodontal destruction. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4710206 Thu, 31 Mar 2011 23:00:00 +0100 4710206 http://www.medworm.com/index.php?rid=4705540&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01355.x Conclusion:  Calprotectin levels were predictors of disease activity at both site and subject levels. The calculated cut‐off values provide a dichotomous basis for prospective evaluation of calprotectin as a diagnostic marker for monitoring periodontal treatment. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4705540 Thu, 31 Mar 2011 23:00:00 +0100 4705540 http://www.medworm.com/index.php?rid=4677666&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01364.x Conclusion:  IL‐1β significantly increased OPG production by HGFs. The statins differed minimally in their effects on OPG and RANKL production by resting and IL‐1β‐activated HGFs. Both statins increased constitutive RANKL/OPG ratios, but generally not IL‐1β‐stimulated ratios. Thus, statins may influence the production of RANKL and OPG by HGFs to favor bone catabolism, under noninflammatory conditions. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4677666 Thu, 31 Mar 2011 23:00:00 +0100 4677666 http://www.medworm.com/index.php?rid=4644493&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01358.x Conclusion:  These results demonstrate that iPS cells can be successfully generated from adult human gingival and periodontal ligament fibroblasts. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4644493 Tue, 29 Mar 2011 15:33:30 +0100 4644493 http://www.medworm.com/index.php?rid=4616609&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01356.x Conclusion: P. gingivalis LPS appears to be an important factor in the development of atherosclerosis by stimulation of atherosclerosis‐related gene expression in both macrophages and foam cells via activation of the NF‐κB pathway. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4616609 Tue, 22 Mar 2011 16:28:34 +0100 4616609 http://www.medworm.com/index.php?rid=4601460&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01357.x Conclusion:  EMD induces not only BMP‐2, but also its receptors and inhibitors, in PDL cells. IL‐1β and biomechanical forces may counteract the beneficial effects of EMD on BMP‐2 activity via the down‐regulation of BMP receptors. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4601460 Thu, 17 Mar 2011 16:18:47 +0100 4601460 http://www.medworm.com/index.php?rid=4581835&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01360.x Conclusion:  The present study shows that simvastatin may alter cell migration by disrupting the cell signaling networks that regulate the actin cytoskeleton dynamics. This mechanism may affect the response of gingival mesenchymal cells during wound healing. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4581835 Mon, 14 Mar 2011 17:28:21 +0100 4581835 http://www.medworm.com/index.php?rid=4571654&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01361.x Conclusion:  In summary, the results of this study revealed that hemodynamic alterations can be detected around diseased peri‐implant sites by optical spectroscopy, and this method may be considered an alternative and feasible approach for the monitoring and diagnosis of peri‐implant diseases. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4571654 Fri, 11 Mar 2011 16:19:27 +0100 4571654 http://www.medworm.com/index.php?rid=4561699&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01349.x Conclusion:  We identified up‐regulated genes (ITGB‐2, MMP‐2, CXCL‐12, CXCR‐4 and Rac‐2) and down‐regulated genes (connexin, DSG‐1, DSC‐1 and nestin) in periodontitis‐affected gingival tissues; these genes may be related to the stimulation of leukocyte transendothelial migration and to the the impairment of cell‐to‐cell communication in periodontitis. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4561699 Wed, 09 Mar 2011 16:17:43 +0100 4561699 http://www.medworm.com/index.php?rid=4536730&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01352.x Conclusion:  The results suggest that local IFN‐γ accelerates osteoclastogenesis in certain conditions of LPS‐induced inflammatory bone loss. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4536730 Wed, 02 Mar 2011 17:15:01 +0100 4536730 http://www.medworm.com/index.php?rid=4536731&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01348.x Conclusion:  Using the rat model, these data suggest CDT intoxication induces cell cycle arrest and damage in periodontal epithelial cells in vivo. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4536731 Tue, 01 Mar 2011 00:00:00 +0100 4536731 http://www.medworm.com/index.php?rid=4502763&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01344.x Conclusion:  Apart from the deletion in the ltx promoter region, no disease‐associated markers were identified. Non‐JP2‐like strains recovered from individuals with periodontal disease exhibited considerable genetic variation regarding aae/apaH genotypes, serotypes and XhoI DNA fingerprints. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4502763 Mon, 21 Feb 2011 00:00:00 +0100 4502763 http://www.medworm.com/index.php?rid=4502762&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01346.x Conclusion:  These findings indicate that LL‐37 induces IL‐8 expression via the P2X7 receptor and the MEK1/2‐dependent p44/42 MAP kinases in HGFs, suggesting both direct and indirect involvement of LL‐37 in neutrophil recruitment into an inflammatory site within diseased periodontal tissues. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4502762 Mon, 21 Feb 2011 00:00:00 +0100 4502762 http://www.medworm.com/index.php?rid=4502761&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2010.01338.x Conclusion:  These findings suggest that FcγRIIB‐nt645+25AA carriers are more likely to experience preterm birth than FcγRIIB‐nt645+25AG and GG carriers. Also, women with FcγRIIB‐nt645+25G exhibited a greater tendency to have periodontitis than those with nt645+25A. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4502761 Mon, 21 Feb 2011 00:00:00 +0100 4502761 http://www.medworm.com/index.php?rid=4490690&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2010.01337.x Conclusions:  The JP2 clone of A. actinomycetemcomitans was not detected in the subgingival plaque of high school subjects in Sudan. The detection of non‐JP2 types of A. actinomycetemcomitans may be a useful marker of increased risk for development of aggressive periodontitis in young subjects. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4490690 Thu, 17 Feb 2011 00:00:00 +0100 4490690 http://www.medworm.com/index.php?rid=4490689&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01345.x Conclusions:  This study showed that the PTH(1–34) effect on ALP activity and osteocalcin production in human PDL cells is maturation state‐dependent and specific in terms of the pathways involved. Whereas in less mature cells the PTH effect is associated with cyclic AMP/protein kinase A‐dependent signaling, more mature cells seem to mediate the PTH signal primarily via protein kinase C‐dependent pathways. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4490689 Thu, 17 Feb 2011 00:00:00 +0100 4490689 http://www.medworm.com/index.php?rid=4490688&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01353.x Conclusion:  Periodontal ligament and gingival fibroblasts respond to P. gingivalis in a different manner and may play different roles in periodontitis. Both subsets of fibroblasts from patients appear more active in interaction with P. gingivalis. Moreover, periodontal ligament fibroblasts from P. gingivalis‐positive donors are more responsive to an in vitro P. gingivalis challenge. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4490688 Thu, 17 Feb 2011 00:00:00 +0100 4490688 http://www.medworm.com/index.php?rid=4451390&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2010.01342.x Conclusion:  Curcumin did not prevent alveolar bone resorption, but its potent anti‐inflammatory effect suggests that it may have a therapeutic potential in periodontal diseases. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4451390 Tue, 08 Feb 2011 00:00:00 +0100 4451390 http://www.medworm.com/index.php?rid=4502760&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01347.x Conclusion:  Although M. oralis was the main species of Archaea associated with both healthy and diseased implant sites, the data indicated an increased prevalence of Archaea in peri‐implantitis sites, and their role in pathogenesis should be further investigated. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4502760 Tue, 01 Feb 2011 00:00:00 +0100 4502760 http://www.medworm.com/index.php?rid=4490687&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2011.01354.x Conclusion:  The balance between FoxO and the Wnt pathway is finely tuned by systemic and local factors, creating a far‐reaching mechanism that dictates the fate of mesenchymal progenitors and regulates the homeostasis of bone, providing a rationale for the impairment of systemic and alveolar bone maintenance clinically observed with age and metabolic diseases. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4490687 Tue, 01 Feb 2011 00:00:00 +0100 4490687 http://www.medworm.com/index.php?rid=4395133&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2010.01335.x Conclusion:  Salivary copy‐counts of P. gingivalis, T. forsythia and P. intermedia appear to have the potential to identify the presence of periodontitis, whereas the salivary level of the other test infectious agents may possess little or no diagnostic utility. Longitudinal studies are warranted to determine the ability of salivary copy‐counts of major periodontopathic bacteria to predict future periodontal breakdown. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4395133 Tue, 25 Jan 2011 00:00:00 +0100 4395133 http://www.medworm.com/index.php?rid=4395132&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2010.01336.x Conclusion:  The findings suggest that the combination therapy demonstrated successful reduction of gingival inflammation, reduction of pocket depth and attachment level gain, accompanied by a trend for modulation of the cytokines profile in gingival crevicular fluid. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4395132 Tue, 25 Jan 2011 00:00:00 +0100 4395132 http://www.medworm.com/index.php?rid=4395131&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2010.01341.x Conclusion:  An in vitro biofilm model was developed and validated, demonstrating a pattern of bacterial colonization and maturation similar to the in vivo development of the subgingival biofilm. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4395131 Tue, 25 Jan 2011 00:00:00 +0100 4395131 http://www.medworm.com/index.php?rid=4395130&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2010.01343.x Conclusion:  This study did not confirm previous findings of periodontal pathogens in atheromas, making it impossible to establish factors associated with their presence in plaques. Presence of bacterial DNA in some samples indicates that periodontal or nonoral bacterial species other than the ones targeted in this study may be involved with some cases of atherosclerosis. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4395130 Tue, 25 Jan 2011 00:00:00 +0100 4395130 http://www.medworm.com/index.php?rid=4362566&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2010.01339.x Conclusion:  Synthetic peptide 19 of P. gingivalis HSP60 is an immunoreactive epitope in the periodontitis–atherosclerosis axis. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4362566 Tue, 18 Jan 2011 00:00:00 +0100 4362566 http://www.medworm.com/index.php?rid=4362565&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2010.01340.x Conclusion:  The results suggested that treatment with CCR2 antagonist inhibited alveolar bone loss and improved bone formation in this model. These data support further evaluation of CCR2 antagonist as a therapeutic target for the development of new treatment modalities on bacterially induced alveolar bone resorption. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4362565 Tue, 18 Jan 2011 00:00:00 +0100 4362565 http://www.medworm.com/index.php?rid=4299060&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2010.01333.x Conclusion:  Taken together, these data show that NIK is important in the bone‐destructive components of inflammation and represents a possible therapeutic target. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4299060 Wed, 29 Dec 2010 00:00:00 +0100 4299060 http://www.medworm.com/index.php?rid=4295847&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2010.01312.x Conclusion:  The increases in cyclin D1, PCNA and CDK4, together with the enhanced phosphorylation of Rb1, suggest that cyclosporine A promotes cell‐cycle progression through the G1/S transition in the gingiva. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4295847 Tue, 28 Dec 2010 00:00:00 +0100 4295847 http://www.medworm.com/index.php?rid=4295846&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2010.01329.x Conclusion:  Lovastatin and simvastatin may stimulate the osteoblastic differentiation of periodontal ligament cells via the ERK1/2 pathway. This suggests that the statins may be useful for regenerating periodontal hard tissue. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4295846 Tue, 28 Dec 2010 00:00:00 +0100 4295846 http://www.medworm.com/index.php?rid=4295845&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2010.01334.x Conclusion:  Photobleaching could be problematic when making quantitative measurements of porphyrin fluorescence in situ. Reducing both light levels and exposure time, in combination with increased camera sensitivity, should be the default approach when undertaking analyses by quantitative light‐induced fluorescence digital. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4295845 Tue, 28 Dec 2010 00:00:00 +0100 4295845 http://www.medworm.com/index.php?rid=4285766&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2010.01330.x Conclusion:  The present study shows the potential regenerative capacity of the CAOMEs by their ability to reach maturity similar to that seen in oral mucosa. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4285766 Thu, 23 Dec 2010 00:00:00 +0100 4285766 http://www.medworm.com/index.php?rid=4246425&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2010.01326.x Conclusion:  These findings demonstrate that challenge with P. gingivalis, but not with A. actinomycetemcomitans, can accelerate, or even initiate, the progression of experimental AAA through the increased expression of MMPs. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4246425 Fri, 10 Dec 2010 00:00:00 +0100 4246425 http://www.medworm.com/index.php?rid=4246424&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2010.01332.x Conclusion:  Periodontitis induces an increase in the output of proteins, including mucin and amylase, thereby enhancing the protective potential of saliva, but this is accompanied by a decrease in flow rate. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4246424 Fri, 10 Dec 2010 00:00:00 +0100 4246424 http://www.medworm.com/index.php?rid=4215064&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2010.01328.x Conclusion:  In summary, the findings of the present study suggest that enhanced adipogenic differentiation and inhibition of collagen synthesis by hPDLSCs appear to be partly responsible for the minimal effect of rhBMP‐2 on cementum and PDL tissue regeneration by hPDLSCs. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4215064 Wed, 01 Dec 2010 00:00:00 +0100 4215064 http://www.medworm.com/index.php?rid=4215063&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2010.01331.x Conclusion:  Therefore, pharmacological treatment of periodontitis should aim to reduce the release of proinflammatory agents not only from classical inflammatory cells but also from periodontal ligament cells. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4215063 Wed, 01 Dec 2010 00:00:00 +0100 4215063 http://www.medworm.com/index.php?rid=4215062&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2010.01327.x Conclusion:  The CC genotype of CD14 (C260T) is related to susceptibility to chronic periodontitis in Caucasians. In addition, differences observed in the distribution of TLR9 (T1486C) genotypes between groups warrant further investigation. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4215062 Wed, 01 Dec 2010 00:00:00 +0100 4215062 http://www.medworm.com/index.php?rid=4215061&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2010.01325.x Conclusion:  Systemic antibodies against A. actionmycetemcomitans leukotoxin were common in this adult Swedish population. These antibodies might contribute to limit the systemic effects of the infection. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4215061 Wed, 01 Dec 2010 00:00:00 +0100 4215061 http://www.medworm.com/index.php?rid=4203844&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2010.01315.x Conclusion:  The severity of periodontal disease increases the extension and the depth of the radicular resorption, and the presence of antagonist forces aggravates the resorption. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4203844 Fri, 26 Nov 2010 00:00:00 +0100 4203844 http://www.medworm.com/index.php?rid=4203843&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2010.01319.x Conclusions:  This study demonstrated that periodontal pathogens antagonize S. mutans quorum‐sensing properties. This may render S. mutans less virulent and less resistant to environmental antibacterial factors. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4203843 Fri, 26 Nov 2010 00:00:00 +0100 4203843 http://www.medworm.com/index.php?rid=4203842&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2010.01320.x Conclusion:  EMD contains a number of high‐molecular‐weight compounds which include the proteinase inhibitors, fetuin A and alpha1‐antichymotrypsin. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4203842 Fri, 26 Nov 2010 00:00:00 +0100 4203842 http://www.medworm.com/index.php?rid=4203841&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2010.01321.x Conclusion:  The set of EMD‐regulated genes identified in this study offers the opportunity to clarify mechanisms underlying the effects of EMD on epithelial cells. Reduced epithelial repopulation of the dental root upon periodontal surgery may be the consequence of reduced migration and cell growth, as well as epithelial‐to‐mesenchymal transition. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4203841 Fri, 26 Nov 2010 00:00:00 +0100 4203841 http://www.medworm.com/index.php?rid=4203840&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2010.01322.x Conclusion:  Our results demonstrated that chitosan–collagen composites might induce in vivo new bone formation around pure titanium implant surfaces. Different molecular weights of chitosan did not show significantly different effects on the osteoinductive potential of the test materials. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4203840 Fri, 26 Nov 2010 00:00:00 +0100 4203840 http://www.medworm.com/index.php?rid=4203839&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2010.01323.x Conclusions:  Peri‐implantitis fibroblasts differ from periodontitis fibroblasts in phenotypic expression of cC1qR and function, and from healthy fibroblasts in proinflammatory, angiogenic and fibrogenic function. Peri‐implantitis fibroblasts may represent a novel subtype. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4203839 Fri, 26 Nov 2010 00:00:00 +0100 4203839 http://www.medworm.com/index.php?rid=4203838&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2010.01324.x Conclusion:  This study shows that IL‐1β and TNF‐α levels in periodontitis patients with T1DM are affected by the duration of diabetes mellitus. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=4203838 Fri, 26 Nov 2010 00:00:00 +0100 4203838 http://www.medworm.com/index.php?rid=3989346&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2010.01316.x Lui J, Corbet EF, Jin L. Combined photodynamic and low‐level laser therapies as an adjunct to nonsurgical treatment of chronic periodontitis. J Periodont Res 2010; doi: 10.1111/j.1600‐0765.2010.01316.x. © 2010 John Wiley & Sons A/S (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=3989346 Thu, 23 Sep 2010 05:48:28 +0100 3989346 http://www.medworm.com/index.php?rid=3930156&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2010.01305.x (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=3930156 Sat, 04 Sep 2010 05:31:05 +0100 3930156 http://www.medworm.com/index.php?rid=3989352&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2010.01304.x Watanabe K, Iizuka T, Adeleke A, Pham L, Shlimon AE, Yasin M, Horvath P, Unterman TG. Involvement of toll‐like receptor 4 in alveolar bone loss and glucose homeostasis in experimental periodontitis. J Periodont Res 2010. doi: 10.1111/j.1600‐0765.2010.01304.x. © 2010 John Wiley & Sons A/S (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=3989352 Tue, 31 Aug 2010 23:00:00 +0100 3989352 http://www.medworm.com/index.php?rid=3989351&cid=s_28245_11_f&fid=28245&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1600-0765.2010.01307.x Song H, Zhao H, Qu Y, Sun Q, Zhang F, Du Z, Liang W, Qi Y, Yang P. Carbon monoxide releasing molecule‐3 inhibits concurrent tumor necrosis factor‐α‐ and interleukin‐1β‐induced expression of adhesion molecules on human gingival fibroblasts. J Periodont Res 2010. doi: 10.1111/j.1600‐0765.2010.01307.x. (Source: Journal of Periodontal Research) Journal of Periodontal Research journals http://www.medworm.com/rss/comments.php?id=3989351 Tue, 31 Aug 2010 23:00:00 +0100 3989351