Journal of Surgical Oncology via MedWorm.com MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Journal of Surgical Oncology' source. Wed, 08 Feb 2012 08:41:46 +0100 Living with rotationplasty—Quality of life in rotationplasty patients from childhood to adulthood http://www.medworm.com/index.php?rid=5666788&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22088 ConclusionsThe assessment of QoL by the SF‐36 questionnaire was effective, and a correspondence was found between what emerged from the quantitative study and the contents of the interview. Knowing the strengths and weaknesses that were highlighted is indispensable for parents and operators when choosing among the various surgical options and to facilitate coming to terms with the injury and the “scars”. J. Surg. Oncol. 2012;105:331–336. © 2012 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5666788 Wed, 08 Feb 2012 13:16:21 +0100 5666788 Does preoperative therapy optimize outcomes in patients with resectable pancreatic cancer? http://www.medworm.com/index.php?rid=5666787&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23044 The objective of this study was to compare survival between all patients with radiographically resectable adenocarcinoma of the proximal pancreas who underwent preoperative chemoradiation therapy (PRE‐OP CRT) or surgical exploration first (SURGERY) with “intention to resect.” Pancreatic cancer patients who undergo resection after PREOP CRT live longer than patients who undergo resection without PREOP CRT, a difference that may be attributable to patient selection. We retrospectively identified 236 patients with pancreatic head adenocarcinoma seen between 1999 and 2007 with sufficient data to be confirmed medically and radiographically resectable. The outcomes of 144 patients who underwent PREOP CRT were compared to those of 92 patients who proceeded straight to SURGERY. The groups we... Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5666787 Wed, 08 Feb 2012 13:14:09 +0100 5666787 Adjuvant treatment of early colon cancer with micrometastases: Results of a national survey http://www.medworm.com/index.php?rid=5659447&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23057 ConclusionsMM in colon cancer apparently influenced adjuvant treatment decisions absent known prognostic benefit. Prospective trials are needed to improve the selection of patients for systemic chemotherapy in early, node‐negative colon cancer. J. Surg. Oncol © 2012 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5659447 Sun, 05 Feb 2012 13:13:44 +0100 5659447 Factors influencing survival in patients undergoing palliative bypass for pancreatic adenocarcinoma http://www.medworm.com/index.php?rid=5659448&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23047 ConclusionsIn a cohort of patients undergoing a palliative bypass procedure, specific peri‐operative factors can be used to identify patients who are at risk of early mortality. These factors may be helpful in selecting appropriate interventions for this group of patients. J. Surg. Oncol © 2012 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5659448 Fri, 03 Feb 2012 05:00:00 +0100 5659448 High dose stereotactic body radiotherapy using three fractions for colorectal oligometastases http://www.medworm.com/index.php?rid=5647106&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23058 ConclusionsHigh dose SBRT for colorectal oligometastases was found to produce results comparable with surgical series. To improve local control, dose higher than 48 Gy are recommend when possible, but further study will be required to define the optimal normal tissue constraints and acceptable toxicity. J. Surg. Oncol © 2012 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5647106 Thu, 02 Feb 2012 13:15:32 +0100 5647106 Follow‐up after primary treatment of soft tissue sarcoma of extremities: Impact of frequency of follow‐up imaging on disease‐specific survival http://www.medworm.com/index.php?rid=5647108&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23060 ConclusionMore frequent follow‐up were associated with improved survival in high‐risk relapsing patients with extremity STS by providing greater opportunities for adequate reoperation. J. Surg. Oncol © 2012 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5647108 Wed, 01 Feb 2012 05:00:00 +0100 5647108 Adjuvant chemotherapy decreases and postpones distant metastasis in extremity stage IIB/III synovial sarcoma patients http://www.medworm.com/index.php?rid=5647107&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23061 ConclusionsPatients with stage IIB/III synovial sarcoma might benefit in DSS, MFS, and a prolonged TTM from AC. J. Surg. Oncol © 2012 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5647107 Wed, 01 Feb 2012 05:00:00 +0100 5647107 Brain metastasis from colorectal cancer: Prognostic factors and survival http://www.medworm.com/index.php?rid=5638164&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23055 ConclusionsThe prognosis of patients with BM from CRC was associated with the curability of the therapy for BM, number of metastatic organs, and the serum CEA level. The modality of treatment had no significant impact on the outcome. J. Surg. Oncol © 2012 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5638164 Sun, 29 Jan 2012 13:15:24 +0100 5638164 The flavonoid MonoHER prevents monocrotaline‐induced hepatic sinusoidal injury in rats http://www.medworm.com/index.php?rid=5638167&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23046 ConclusionsMonoHER prevented MCT induced portal hypertension and hepatic injury in rats. J. Surg. Oncol © 2012 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5638167 Fri, 27 Jan 2012 05:00:00 +0100 5638167 High expression of CD73 as a poor prognostic biomarker in human colorectal cancer http://www.medworm.com/index.php?rid=5638166&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23056 ConclusionsHigh expression of CD73 can be an independent and useful biomarker for predicting the poor survival of patients with CRC. J. Surg. Oncol © 2012 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5638166 Fri, 27 Jan 2012 05:00:00 +0100 5638166 The promoting effect of adiponectin in hepatocellular carcinoma http://www.medworm.com/index.php?rid=5638165&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23059 ConclusionsIncreased adiponectin expressions were found in HCC and this increase might contribute to tumor growth. J. Surg. Oncol © 2012 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5638165 Fri, 27 Jan 2012 05:00:00 +0100 5638165 Tumor spectrum in lynch syndrome, DNA mismatch repair system and endogenous carcinogens http://www.medworm.com/index.php?rid=5628138&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23054 AbstractInactivation of Mismatch Repair genes in Lynch Syndrome, caused by inherited mutations, decreases the ability to repair DNA errors throughout life. This deficit may allow the development of any tumor type. Nevertheless, the Syndrome develops a specific tumor spectrum associated with the disease. We think that such spectrum of tumors would be related to the action of certain endogenous carcinogens such as bile acids and estrogens that aggravate the inherited defect. J. Surg. Oncol © 2012 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5628138 Thu, 26 Jan 2012 13:16:10 +0100 5628138 Radiofrequency ablation combined with systemic chemotherapy in nasopharyngeal carcinoma liver metastases improves response to treatment and survival outcomes http://www.medworm.com/index.php?rid=5628139&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23034 ConclusionsRFA combined with chemotherapy is a promising treatment for NPC metastatic liver disease with improved local response, PFS, and OS compared to current chemotherapy protocols. J. Surg. Oncol © 2012 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5628139 Mon, 23 Jan 2012 05:00:00 +0100 5628139 Free peritoneal tumor cells detection in gastric and colorectal cancer patients http://www.medworm.com/index.php?rid=5608233&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23052 ConclusionsEpithelial immunoenrichment and immunofluorescence analysis allows unequivocal identification of the FPTC. The real time qRT‐PCR showed higher sensitivity for the detection of CEA and CK20 mRNA levels and confirmed its prognostic value in gastrointestinal cancers. J. Surg. Oncol © 2012 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5608233 Fri, 20 Jan 2012 13:16:52 +0100 5608233 Erratum: Relation of MT1‐MMP gene expression to outcomes in colorectal cancer http://www.medworm.com/index.php?rid=5608238&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23043 (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5608238 Wed, 18 Jan 2012 05:00:00 +0100 5608238 Is transureteroureterostomy performed during multi‐organ resection for non‐urothelial malignancy safe and effective? http://www.medworm.com/index.php?rid=5608236&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23039 ConclusionsTUU during multi‐organ resection for non‐urothelial malignancy is safe and effective. Long‐term renal function is maintained in the majority of patients. J. Surg. Oncol © 2012 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5608236 Wed, 18 Jan 2012 05:00:00 +0100 5608236 Extensive nodal involvement increases the positivity of blue nodes in the axillary reverse mapping procedure in patients with breast cancer http://www.medworm.com/index.php?rid=5608235&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23048 ConclusionsThe ARM technique is feasible in patients undergoing NAC. Patients with extensive nodal involvement have increased risk of having positive blue nodes. More studies are needed to assess the subgroup of patients with positive axilla that may have the blue node spared without compromising the oncological treatment. J. Surg. Oncol © 2012 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5608235 Wed, 18 Jan 2012 05:00:00 +0100 5608235 Participation and conflict in the decision‐making process for endoscopic resection or surgical gastrectomy for early gastric cancer http://www.medworm.com/index.php?rid=5608234&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23049 ConclusionDespite the high overall decisional conflict, patients with preference for endoscopic treatment tended to be more autonomous. After consultation, all patients exhibited a passive participation role in the decision‐making process. J. Surg. Oncol © 2012 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5608234 Wed, 18 Jan 2012 05:00:00 +0100 5608234 Malignant triton tumors—complete surgical resection and adjuvant radiotherapy associated with improved survival http://www.medworm.com/index.php?rid=5608241&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23042 ConclusionComplete surgical resection and adjuvant radiotherapy should be the cornerstones of treatment for MTT. J. Surg. Oncol © 2012 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5608241 Tue, 17 Jan 2012 05:00:00 +0100 5608241 Analytic lymph node number establishes staging accuracy by occult tumor burden in colorectal cancer http://www.medworm.com/index.php?rid=5608240&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23051 ConclusionsThe prognostic utility of occult tumor burden assessed by GUCY2C RT‐qPCR is dependent on the number of analytic lymph nodes. J. Surg. Oncol © 2012 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5608240 Tue, 17 Jan 2012 05:00:00 +0100 5608240 Indocyanine green fluorescence‐navigated sentinel node biopsy showed higher sensitivity than the radioisotope or blue dye method, which may help to reduce false‐negative cases in skin cancer http://www.medworm.com/index.php?rid=5608239&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23045 ConclusionICG‐FI detected SLNs more efficiently than did the conventional methods, and these “occult” SLNs may offer an explanation for some false‐negative cases. We recommend using ICG‐FI in addition to a conventional method to reduce the risk of overlooking these “occult” SLNs. J. Surg. Oncol © 2012 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5608239 Tue, 17 Jan 2012 05:00:00 +0100 5608239 Increased expression of HMGB1 is associated with poor prognosis in human bladder cancer http://www.medworm.com/index.php?rid=5581069&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23040 ConclusionsHMGB1 might be a new molecular marker to predict the prognosis of patients with BC. J. Surg. Oncol © 2012 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5581069 Fri, 13 Jan 2012 13:11:47 +0100 5581069 Improved guideline compliance after a 3‐year audit of multidisciplinary colorectal cancer care in the western part of the netherlands http://www.medworm.com/index.php?rid=5581072&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23038 ConclusionsAfter the feedback of benchmark information, compliance with guidelines for diagnosis and treatment of colorectal cancer patients improved, and differences between individual hospitals decreased. Although secular trends cannot be ruled out, it is highly likely that these results can be attributed to the audit. J. Surg. Oncol © 2012 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5581072 Tue, 10 Jan 2012 05:00:00 +0100 5581072 Comparison of hepatocellular carcinoma in American and Asian patients by tissue array analysis http://www.medworm.com/index.php?rid=5581071&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23036 ConclusionThese data likely correlate with differences in molecular pathogenesis of HCC based on racial and regional differences. These findings may have implications in choice of molecular targeted therapies based on patient ethnicity. J. Surg. Oncol © 2012 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5581071 Tue, 10 Jan 2012 05:00:00 +0100 5581071 Completeness of dictated operative reports in breast cancer—the case for synoptic reporting http://www.medworm.com/index.php?rid=5581070&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23031 ConclusionsThe dictated operative report for breast cancer surgery does not adequately capture important data. A synoptic reporting system, which requires documentation of important elements, is a potentially beneficial tool in breast cancer surgery. J. Surg. Oncol © 2012 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5581070 Tue, 10 Jan 2012 05:00:00 +0100 5581070 Overexpression of thrombospondin‐1 in stromal myofibroblasts is associated with tumor growth and nodal metastasis in gastric carcinoma http://www.medworm.com/index.php?rid=5581076&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23037 ConclusionsThis clinical study revealed that overexpression of THBS‐1 in stromal myofibroblasts is associated with tumor growth and nodal metastasis in gastric carcinoma. THBS‐1 may activate latent transforming growth factor‐β1 to stimulate fibroblasts to differentiate into myofibroblasts, though further studies are needed to validate this hypothesis. These results suggest that THBS‐1 and myofibroblasts may serve as novel targets for strategies aimed at protection against and treatment of gastric carcinoma. J. Surg. Oncol © 2012 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5581076 Mon, 09 Jan 2012 05:00:00 +0100 5581076 Abnormal expression of E‐cadherin in tumor cells is associated with poor prognosis of gastric carcinoma http://www.medworm.com/index.php?rid=5581075&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23008 ConclusionWe found significant correlation among HGF/c‐Met, E‐cadherin expression and worse prognosis of patients with GC. Abnormal E‐cadherin expression may serve as an independent predictive factor for prognosis of GC patients. J. Surg. Oncol © 2012 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5581075 Mon, 09 Jan 2012 05:00:00 +0100 5581075 Perioperative mortality in patients with myelodysplastic syndrome http://www.medworm.com/index.php?rid=5581074&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23032 ConclusionOutcomes in MDS patients are poor with expected survival less than 2 years and high postoperative mortality in the setting of urgent/emergent operations. While maybe not prohibitive, we believe it is an imperative part of the informed consent process particularly for urgent/emergent procedures. J. Surg. Oncol © 2012 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5581074 Mon, 09 Jan 2012 05:00:00 +0100 5581074 Perioperative change in peripheral blood monocyte count may predict prognosis in patients with colorectal liver metastasis after hepatic resection http://www.medworm.com/index.php?rid=5581073&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23033 ConclusionsPerioperative change in peripheral blood monocyte count is an independent risk factor for overall survival after hepatic resection for CRLM, and may reflect immunosuppressive state. J. Surg. Oncol © 2012 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5581073 Mon, 09 Jan 2012 05:00:00 +0100 5581073 Strong YB‐1 expression is associated with liver metastasis progression and predicts shorter disease‐free survival in advanced gastric cancer http://www.medworm.com/index.php?rid=5559505&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23030 ConclusionsOur results indicate that YB‐1 plays a role in the process of GC metastasis, and that the immunohistochemical detection of this protein potentially delivers valuable insight regarding the prediction of liver metastasis and shorter DFS in patients undergoing curative resection for advanced GC. J. Surg. Oncol © 2012 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5559505 Wed, 04 Jan 2012 17:41:38 +0100 5559505 Role of intraoperative ultrasonography for pancreatic schwannoma http://www.medworm.com/index.php?rid=5559507&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.21979 (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5559507 Tue, 03 Jan 2012 05:00:00 +0100 5559507 Updates on the multimodality management of desmoplastic small round cell tumor http://www.medworm.com/index.php?rid=5559506&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22130 AbstractDesmoplastic Small Round Cell Tumor (DSRCT) is a rare and an aggressive malignancy with poor outcome. This tumor can co‐express epithelial, neural, and mesenchymal markers. The molecular hallmark of DSRCT is the EWS–WT1 fusion protein. Despite the diversities in treatment modality, the best results have been seen with radical surgery and adjuvant or neoadjuvant chemotherapy. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5559506 Tue, 03 Jan 2012 05:00:00 +0100 5559506 Down‐regulation of RhoE is associated with progression and poor prognosis in hepatocellular carcinoma http://www.medworm.com/index.php?rid=5552074&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23019 ConclusionsRhoE, down‐regulated in patients with HCC, could serve as an independent prognostic predictor for patients with HCC. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5552074 Sat, 31 Dec 2011 01:44:10 +0100 5552074 Prognostic impact of tumor encapsulation in patients with large hepatocellular carcinoma http://www.medworm.com/index.php?rid=5552075&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23029 (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5552075 Wed, 28 Dec 2011 05:00:00 +0100 5552075 Reirradiation to the pelvis for recurrent rectal cancer http://www.medworm.com/index.php?rid=5544227&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23023 ConclusionsTumor location (axial or anterior) and surgery after reirradiation may increase severe late toxicity. In addition, an EQD2 exceeding 50 Gyαβ10 may improve infield control. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5544227 Wed, 28 Dec 2011 04:54:34 +0100 5544227 Primary surgical treatment of T2 oropharyngeal carcinoma http://www.medworm.com/index.php?rid=5544239&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23026 ConclusionsPrimary surgical treatment of T2 OPC proved to be an effective treatment modality with a low rate of complications and satisfactory functional results. Complete tumor excision is essential and a neck dissection is justified. Most patients need adjuvant radiotherapy. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5544239 Tue, 27 Dec 2011 05:00:00 +0100 5544239 High‐grade osteosarcoma treated with hemicortical resection and biological reconstruction http://www.medworm.com/index.php?rid=5544238&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23005 ConclusionsHemicortical resection for high‐grade osteosarcomas located eccentrically in the long bones may be a reliable technique leading to good joint function by preserving surrounding healthy tissues. The functional outcome was encouraging, although long‐term follow‐up is mandatory to validate. With the advancement of chemotherapy and radiographic three‐dimensional imaging, the safe margin in wide excision of high‐grade osteosarcoma may be narrowed down in light of joint surface preservation. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5544238 Tue, 27 Dec 2011 05:00:00 +0100 5544238 Routine prophylactic sentinel lymph node biopsy is not indicated in women undergoing prophylactic mastectomy http://www.medworm.com/index.php?rid=5544237&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23018 ConclusionsAlthough it is not uncommon to find occult carcinomas in the prophylactic breast, it is rare for the occult carcinoma to spread to the lymph nodes. Therefore, routine prophylactic SLNB is not indicated in patients undergoing PM. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5544237 Tue, 27 Dec 2011 05:00:00 +0100 5544237 Clinicopathological prognostic factors of superficial non‐small round cell soft tissue sarcomas http://www.medworm.com/index.php?rid=5544236&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23025 ConclusionsFascial invasion on pathological examination of resected specimens was identified as a significant unfavorable prognostic factor. Selecting the postoperative adjuvant therapy based on a detailed evaluation of any fascial invasion is an important part of the therapeutic strategy. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5544236 Tue, 27 Dec 2011 05:00:00 +0100 5544236 Primary excision compared with re‐excision of extremity soft tissue sarcomas—is anything new? http://www.medworm.com/index.php?rid=5544235&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23021 ConclusionsThere were no differences in death, metastases, or local recurrence between the two groups after adjusting for high‐risk variables. Survival advantages previously reported with STS re‐excision serve as proxy for tumors that have a better survival profile. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5544235 Tue, 27 Dec 2011 05:00:00 +0100 5544235 Prognostic significance of lymph node station 7 for patients with gastric cancers underwent radical surgery http://www.medworm.com/index.php?rid=5544234&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23011 ConclusionIt might be more suitable for cancers in Group B being classified as level‐based n1 stage disease. And we recommend the anatomical location of metastatic lymph nodes also being considered in the categorization of lymph node metastasis. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5544234 Tue, 27 Dec 2011 05:00:00 +0100 5544234 Overexpression of ZEB1 relates to metastasis and invasion in osteosarcoma http://www.medworm.com/index.php?rid=5544233&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23012 ConclusionsThe overexpression of ZEB1 in osteosarcoma may be related to the carcinogenesis and development as well as metastasis and invasion of osteosarcoma. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5544233 Tue, 27 Dec 2011 05:00:00 +0100 5544233 Epithelial–mesenchymal transition and mesenchymal–epithelial transition via regulation of ZEB‐1 and ZEB‐2 expression in pancreatic cancer http://www.medworm.com/index.php?rid=5544232&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23020 ConclusionsIn primary pancreatic tumors and metastatic lymph nodes, high and low expression of ZEB‐1 and ZEB‐2 was associated with mesenchymal and epithelial phenotype of cancer cells, respectively. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5544232 Tue, 27 Dec 2011 05:00:00 +0100 5544232 Composite biological reconstruction following total calcanectomy of primary calcaneal tumors http://www.medworm.com/index.php?rid=5544231&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23022 ConclusionsVascularized fibular flaps in combination with massive allografts provide an excellent option for biological reconstruction after total calcanectomy in tumor situation and have proven to be a successful limb salvage procedure, which result in earlier patient recovery and return of function.Level of EvidenceTherapeutic Level IV. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5544231 Tue, 27 Dec 2011 05:00:00 +0100 5544231 Expression patterns of endothelin‐1 and its receptors in colorectal cancer http://www.medworm.com/index.php?rid=5544230&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23017 ConclusionsET‐1 and ETAR, but not ETBR, are expressed at a higher level in primary and cultured colon carcinoma cells as compared to normal colon mucosa cells. Further functional studies are needed to explore the role of ET‐1/ETAR axis in colon carcinogenesis. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5544230 Tue, 27 Dec 2011 05:00:00 +0100 5544230 Mechanism and function of decreased FOXO1 in renal cell carcinoma http://www.medworm.com/index.php?rid=5544229&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23013 ConclusionReduced expression of FOXO1 is common in RCC and a potentially suitable marker of different histological subtypes and prognosis of cRCC. Increasing expression of FOXO1 by the miR‐27a inhibitor could prevent cell growth. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5544229 Tue, 27 Dec 2011 05:00:00 +0100 5544229 Comparison of radioguided occult lesion localization (ROLL) and wire localization for non‐palpable breast cancers: A meta‐analysis http://www.medworm.com/index.php?rid=5544228&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23016 AbstractFour randomized trials encompassing 449 patients of non‐palpable breast cancer undergoing with radio‐guided occult lesion localization (ROLL) or wire guided localization (WGL). In the fixed effects model, accurate localization, peri‐procedural complications, and reoperation rate were comparable between two techniques. Risk of having positive resection margins following WGL was higher. Duration of localization and surgical excision was shorter for ROLL. Volume and weight of the excised occult breast lesion was similar in WGL and ROLL groups. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5544228 Tue, 27 Dec 2011 05:00:00 +0100 5544228 Operative management for recurrent and metastatic adrenocortical carcinoma http://www.medworm.com/index.php?rid=5524182&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23015 ConclusionsResection of recurrent or metastatic ACC is safe, and may result in prolongation of survival in selected patients with DFI greater than 1 year. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5524182 Thu, 22 Dec 2011 01:45:45 +0100 5524182 Neoadjuvant chemotherapy with FOLFOX: Improved outcomes in Chinese patients with locally advanced gastric cancer http://www.medworm.com/index.php?rid=5524184&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23009 ConclusionPeri‐operative treatment with FOLFOX shows promise in patients with resectable locally advanced gastric cancer. It warrants further evaluation and should be considered an alternative to peri‐operative ECF. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5524184 Tue, 20 Dec 2011 05:00:00 +0100 5524184 The decision criterion of histological mixed type in “T1/T2” gastric carcinoma—comparison between TNM classification and Japanese classification of gastric cancer http://www.medworm.com/index.php?rid=5524183&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23010 ConclusionsThe presence of undifferentiated component in differentiated T1/T2 gastric cancer is associated with tumor progression. Therefore, the decision criterion of histological mixed type in TNM classification is better suited than JCGC in T1/T2 gastric cancer. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5524183 Tue, 20 Dec 2011 05:00:00 +0100 5524183 Preoperative serum value of sialyl Lewis X predicts pathological nodal extension and survival in patients with surgically treated small cell lung cancer http://www.medworm.com/index.php?rid=5504396&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23002 ConclusionsSerum SLX values were associated with pathological stage and survival after surgery in SCLC patients. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5504396 Fri, 16 Dec 2011 01:46:20 +0100 5504396 The number of pathologic lymph nodes involved is still a significant prognostic factor even after neoadjuvant chemoradiotherapy in esophageal squamous cell carcinoma http://www.medworm.com/index.php?rid=5494663&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23007 ConclusionsOf the various factors, the number of pathologic metastatic LNs was the strongest indicator to predict the patients' survival. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5494663 Tue, 13 Dec 2011 01:50:33 +0100 5494663 Comparison of circumferential resection margin clearance criteria with survival after surgery for cancer of esophagus http://www.medworm.com/index.php?rid=5494665&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23006 ConclusionThis study appears to lend credence to the RCP criteria for definition of CRM over the CAP criteria. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5494665 Mon, 12 Dec 2011 05:00:00 +0100 5494665 Self‐expanding metal stents (SEMS) for patients with advanced Esophageal cancer in Malawi: An effective palliative treatment http://www.medworm.com/index.php?rid=5494664&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23003 ConclusionsSEMS is an appropriate palliative treatment in a resource‐limited environment. For the vast majority of patients a single intervention provides lasting improvement of dysphagia. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5494664 Mon, 12 Dec 2011 05:00:00 +0100 5494664 Encapsulation is a significant prognostic factor for better outcome in large hepatocellular carcinoma http://www.medworm.com/index.php?rid=5486486&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22060 ConclusionsTumor encapsulation is a significant prognostic factor for HCC >5 cm. J. Surg. Oncol. 2012; 105:85–90. © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5486486 Sat, 10 Dec 2011 01:55:39 +0100 5486486 Outcomes following oesophageal stent insertion for palliation of malignant strictures: A large single centre series http://www.medworm.com/index.php?rid=5486485&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22059 ConclusionOesophageal stent insertion provides good palliation for malignant dysphagia, however recurrent dysphagia remains a problem. This major complication occurs more frequently with covered Niti S stents than double‐layered Niti S stents. This finding may aid the stent choice used in advanced oesophageal malignancy. J. Surg. Oncol. 2012; 105:60–65. © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5486485 Sat, 10 Dec 2011 01:55:33 +0100 5486485 Intravenous electrocardiography helps inexperienced operators to place totally implantable venous access device more accurately http://www.medworm.com/index.php?rid=5486484&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.23000 ConclusionIV‐ECG is a safe and convenient method to help inexperienced operators placing TIVAD. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5486484 Sat, 10 Dec 2011 01:53:04 +0100 5486484 Estimating underreported N2 disease in rectal cancer patients with low lymph node counts http://www.medworm.com/index.php?rid=5468496&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22158 ConclusionUtilizing estimated probabilities of N2 disease improves our ability to predict survival, in particular in patients with low LN count. These probabilities allow for a simple rule in patient counseling and clinical decision making. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5468496 Thu, 01 Dec 2011 05:00:00 +0100 5468496 Definitive chemoradiotherapy in patients with esophageal adenocarcinoma: An alternative to surgery? http://www.medworm.com/index.php?rid=5457035&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22157 ConclusionsThe results of the study do not support definitive CRT as an alternative to surgery in esophageal ADC treatment. Definitive CRT should be reserved for patients with a major operative risk. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5457035 Thu, 01 Dec 2011 01:47:31 +0100 5457035 Reconstruction of the pulmonary trunk via cardiopulmonary bypass in extended resection of locally advanced lung malignancies http://www.medworm.com/index.php?rid=5457036&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22159 ConclusionsCPB‐supported extended resection of lung malignancies involving the pulmonary trunk is feasible. Left anterolateral thoracotomy through the fourth intercostal space with right atrial‐aortic cannulation would be the convenient approach. Survival may be prolonged in some selected patients. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5457036 Mon, 28 Nov 2011 05:00:00 +0100 5457036 Nuclear localization of 14‐3‐3epsilon inversely correlates with poor long‐term survival of patients with colorectal cancer http://www.medworm.com/index.php?rid=5431395&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22152 ConclusionsThe current data provide evidence that 14‐3‐3ε is not exclusively a cytosolic protein, but is also detectable within the nucleus. Our results suggest that nuclear 14‐3‐3ε as a suppressor may serve as important biomarker of tumor metastasis. Loss of nuclear 14‐3‐3ε is closely associated with poor overall survival in CRC patients. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5431395 Tue, 22 Nov 2011 01:48:39 +0100 5431395 Thoracic recurrent laryngeal lymph node metastases predict cervical node metastases and benefit from three‐field dissection in selected patients with thoracic esophageal squamous cell carcinoma http://www.medworm.com/index.php?rid=5431401&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22148 ConclusionsMetastasis to RLN LNs is a reliable indicator of cervical LN metastasis in middle/lower thoracic esophageal cancer, while 3FL offers survival benefit over 2FL in certain patient subgroups. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5431401 Mon, 21 Nov 2011 05:00:00 +0100 5431401 Effect of surgeon specialization on long‐term survival following colon cancer resection at an NCI‐designated cancer center http://www.medworm.com/index.php?rid=5431400&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22154 ConclusionSurgeon specialization appears to be associated with improved overall survival in the setting of an NCI‐designated cancer center. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5431400 Mon, 21 Nov 2011 05:00:00 +0100 5431400 Clinical significance of MicoRNA‐155 expression in human breast cancer http://www.medworm.com/index.php?rid=5431399&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22153 ConclusionsMiR‐155 expression might be an independent prognostic factor and a therapeutic target for human breast cancer. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5431399 Mon, 21 Nov 2011 05:00:00 +0100 5431399 Aquaporins in human breast cancer: Identification and involvement in carcinogenesis of breast cancer http://www.medworm.com/index.php?rid=5431398&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22155 ConclusionsThese observations suggested that several subtypes of the AQP family play a role in human breast carcinogenesis. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5431398 Mon, 21 Nov 2011 05:00:00 +0100 5431398 Impact of lymph node retrieval on surgical outcomes in colorectal cancers http://www.medworm.com/index.php?rid=5431397&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22156 ConclusionOur data emphasize the importance of lymph node harvesting during the surgical resection of CRCs. In addition, LNR is a strong independent factor associated with CRC survival. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5431397 Mon, 21 Nov 2011 05:00:00 +0100 5431397 Splenic hilar lymph node metastasis independently predicts poor survival for patients with gastric cancers in the upper and/or the middle third of the stomach http://www.medworm.com/index.php?rid=5431396&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22149 ConclusionsSplenic hilar lymph node metastasis should be considered as one of incurable factors. Consequently, the efficiency of splenectomy aiming at prolonging survival for patients with high risk of splenic hilar lymph nodes metastasis should be questioned, although resection of invasive organs form gastric cancers has been recommended if R0 surgery could be achieved. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5431396 Mon, 21 Nov 2011 05:00:00 +0100 5431396 The quality of life trajectory of resected gastric cancer http://www.medworm.com/index.php?rid=5421675&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22139 ConclusionsSurgery adversely affects QoL for up to 6 months. Thereafter, QoL mirrors changes in disease status. More studies are required to document the QoL cost‐benefit ratio in gastric cancer, which often is accompanied by short survival benefits. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5421675 Sat, 19 Nov 2011 01:46:22 +0100 5421675 Clinical significance of zinc finger E‐box binding homeobox 1 (ZEB1) in human gastric cancer http://www.medworm.com/index.php?rid=5421681&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22142 ConclusionsZEB1 is an independent factor for peritoneal dissemination in patients with gastric cancer, and may therefore play a key role in the progression to peritoneal dissemination in gastric cancer patients. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5421681 Thu, 17 Nov 2011 05:00:00 +0100 5421681 Bilateral neck metastases in upper aero‐digestive tract cancer: Emphasis on the distribution of lymphatic metastases and prognostic implications http://www.medworm.com/index.php?rid=5421680&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22145 ConclusionBNM at lower neck nodes can be a significant prognostic factor for early systemic dissemination and worse prognosis in UADTC patients. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5421680 Thu, 17 Nov 2011 05:00:00 +0100 5421680 Evaluation of a hydrogel based breast biopsy marker (HydroMARK®) as an alternative to wire and radioactive seed localization for non‐palpable breast lesions http://www.medworm.com/index.php?rid=5421679&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22146 ConclusionsWhile intraoperative sonographic visibility was excellent, a large number of excisions were associated with extrusion of the marker. Modifications are needed to improve acceptability of this marker for intra‐operative localization independent of pre‐operative wire or seed localization. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5421679 Thu, 17 Nov 2011 05:00:00 +0100 5421679 Decreased expression of V‐set and immunoglobulin domain containing 1 (VSIG1) is associated with poor prognosis in primary gastric cancer http://www.medworm.com/index.php?rid=5421678&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22150 ConclusionsOur findings suggest that silencing VSIG1 may play an important role in gastric carcinogenesis and that VSIG1 may serve as a prognostic marker as well as a potential therapeutic target for gastric cancer. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5421678 Thu, 17 Nov 2011 05:00:00 +0100 5421678 Decreased expression of Beclin 1 correlates with a metastatic phenotypic feature and adverse prognosis of gastric carcinomas http://www.medworm.com/index.php?rid=5421677&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22151 ConclusionsOur findings provide a basis for the concept that decreased expression of Beclin 1 in GC may be important in the acquisition of a metastatic phenotype, suggesting that decreased Beclin 1 expression, as examined by IHC, is an independent biomarker for poor prognosis of patients with GC. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5421677 Thu, 17 Nov 2011 05:00:00 +0100 5421677 A study of UbcH10 expression and its association with recurrence of meningiomas http://www.medworm.com/index.php?rid=5421676&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22141 ConclusionWe conclude that UbcH10 may play important roles in the development of meningioma, high UbcH10 labeling index indicates higher grade of meningioma, and UbcH10 may be a useful molecular marker for predicting the prognosis of meningioma. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5421676 Thu, 17 Nov 2011 05:00:00 +0100 5421676 Special considerations in pediatric gastrointestinal tumors http://www.medworm.com/index.php?rid=5400130&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.21868 AbstractPediatric gastrointestinal tumors are rare in children but are being increasingly recognized. These tumors have distinct biologic and clinical feature that are different from those observed in adults. This review highlights the biological and clinical characteristics of pediatric GIST and provides diagnostic and therapeutic guidelines for the management these unique and challenging group of tumors. J. Surg. Oncol. 2011; 104:928–932. © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5400130 Sun, 13 Nov 2011 01:48:37 +0100 5400130 Surveillance strategies for gastrointestinal stromal tumors http://www.medworm.com/index.php?rid=5400129&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.21862 AbstractAlthough only 10–30% of gastrointestinal stromal tumors (GISTs) are clinically malignant, all have some degree of malignant potential. The management of high risk patients should be evidence based. However, prospective data and a consensus for guidelines concerning the screening of asymptomatic high risk patients and surveillance following multidisciplinary treatment do not exist. This review provides an overview of GIST, with an emphasis on the available data regarding screening and surveillance of certain populations with GISTs. J. Surg. Oncol. 2011; 104:921–927. © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5400129 Sun, 13 Nov 2011 01:48:36 +0100 5400129 Imaging modalities of gastrointestinal stromal tumors http://www.medworm.com/index.php?rid=5400128&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.21871 This article reviews the current roles of different imaging modalities in clinical management of the gastrointestinal stromal tumors. J. Surg. Oncol. 2011; 104:907–914. © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5400128 Sun, 13 Nov 2011 01:48:34 +0100 5400128 Systemic therapy for advanced gastrointestinal stromal tumors: Beyond imatinib http://www.medworm.com/index.php?rid=5400127&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.21872 AbstractProgression on first‐line therapy with imatinib in gastrointestinal stromal tumors (GIST) is caused by either initial resistance or more often a secondary mutation in tyrosine kinases KIT or PDGFR. Therapies in development for imatinib‐resistant GIST include agents that target KIT/PDGFR with greater potency or possess broader kinase inhibition profiles including VEGFR. To circumvent secondary mutations in KIT/PDGFR, inhibition of the downstream signaling in PI3K/Akt/mTOR pathway and enhanced degradation of KIT/PDGFR are also under investigation. J. Surg. Oncol. 2011; 104:901–906. © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5400127 Sun, 13 Nov 2011 01:48:32 +0100 5400127 Adjuvant imatinib therapy for gastrointestinal stromal tumors http://www.medworm.com/index.php?rid=5400126&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22002 AbstractSurgery is the standard of care for primary resectable gastrointestinal stromal tumors (GISTs), but half of surgically treated patients relapse. Imatinib (IM) has been shown to prolong recurrence‐free survival after complete surgery and is now approved as adjuvant therapy (400 mg/day) for high‐risk GIST patients. IM is well tolerated, with mild to moderate side effects observed. Whether adjuvant IM prolongs overall survival is under evaluation in two ongoing clinical trials. J. Surg. Oncol. 2011; 104:896–900. © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5400126 Sun, 13 Nov 2011 01:48:31 +0100 5400126 Advanced or metastatic gastrointestinal stromal tumors: Systemic treatment options http://www.medworm.com/index.php?rid=5400125&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.21930 AbstractGastrointestinal stromal tumor (GIST), the most common sarcoma arising in the gastrointestinal tract, typically expresses the tyrosine‐kinase receptor, C‐KIT, and contains activating mutation in the c‐kit or platelet‐derived growth factor receptor (pdgfr) gene. Recently, development of small molecules that inhibit the kinase activity of mutant C‐KIT and PDGFR proteins has radically changed treatment and prognosis of patients diagnosed with advanced GIST as this molecularly “targeted” therapy has demonstrated remarkable high‐level of activity in this disease. J. Surg. Oncol. 2011; 104:888–895. © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5400125 Sun, 13 Nov 2011 01:48:30 +0100 5400125 Morphology of gastrointestinal stromal tumors: Historical perspectives http://www.medworm.com/index.php?rid=5400124&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.21873 AbstractAbout 2/3 of gastrointestinal stromal tumors occur in the stomach and about 1/5 in the small intestine with few in the rectum, colon, and esophagus. Their cells are related to the interstitial cells of Cajal. They differ by site in terms of cell type and growth pattern. Benign and malignant tumors are separated based on their light microscopic appearances, size as measured by innumerable pathologists and assistants and mitotic counts. J. Surg. Oncol. 2011; 104:874–881. © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5400124 Sun, 13 Nov 2011 01:48:28 +0100 5400124 Histopathology of gastrointestinal stromal tumor http://www.medworm.com/index.php?rid=5400123&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.21945 AbstractGastrointestinal stromal tumor (GIST), generally driven by oncogenic KIT or PDGFRA mutations, is the most common mesenchymal tumor of the gastrointestinal (GI) tract. GIST is most common in the stomach (60%) and small intestine (30%), but can occur anywhere in the GI‐tract and the intra‐abdominal soft tissues. GIST can show spindle cell or epithelioid morphology, and mitotic count and tumor size are most important prognostic parameters. GISTs in NF1 patients and children are distinctive clinicopathologic groups. Immunohistochemical testing for KIT and sometimes for DOG1/Ano 1 is essential in confirming the diagnosis. J. Surg. Oncol. 2011; 104:865–873. © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5400123 Sun, 13 Nov 2011 01:48:26 +0100 5400123 The molecular evolution of surgical oncology http://www.medworm.com/index.php?rid=5400122&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22050 (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5400122 Sun, 13 Nov 2011 01:48:25 +0100 5400122 Tribute to Alfred E. Chang http://www.medworm.com/index.php?rid=5400121&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22036 (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5400121 Sun, 13 Nov 2011 01:48:24 +0100 5400121 The influence of postoperative glycemic control on recurrence after curative resection in diabetics with hepatitis C virus‐related hepatocellular carcinoma http://www.medworm.com/index.php?rid=5400113&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22137 ConclusionsCareful control of plasma glucose should be performed to prevent tumor recurrence after curative resection for HCV‐related HCC in patients with diabetes. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5400113 Sun, 13 Nov 2011 01:46:21 +0100 5400113 Overexpression of survivin is correlated with increased invasion and metastasis of colorectal cancer http://www.medworm.com/index.php?rid=5400119&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22134 ConclusionTargeting survivin will be a potential strategy to suppress metastasis of CRC. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5400119 Mon, 07 Nov 2011 05:00:00 +0100 5400119 Clinical efficacy of paclitaxel/cisplatin as an adjuvant chemotherapy for patients with cervical cancer who underwent radical hysterectomy and systematic lymphadenectomy http://www.medworm.com/index.php?rid=5400118&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22136 ConclusionsPostoperative chemotherapy using TP might be more beneficial for survival than adjuvant RT and can reduce postoperative complications for cervical cancer patients treated with radical hysterectomy. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5400118 Mon, 07 Nov 2011 05:00:00 +0100 5400118 Prognostic values of the miR‐17‐92 cluster and its paralogs in colon cancer http://www.medworm.com/index.php?rid=5400117&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22138 ConclusionsThe miR‐17‐92 cluster and its paralogs were significantly elevated in patients with colon cancer, and heightened expression of miR‐17 was associated with poor survival. Moreover, miR‐17 and TNM staging were both identified as significant, but independent, prognostic biomarkers in colon cancer. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5400117 Mon, 07 Nov 2011 05:00:00 +0100 5400117 Influence of uncommon histology on breast conservation therapy for breast cancer‐biology dictates technique? http://www.medworm.com/index.php?rid=5400116&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22132 ConclusionsPatients with uncommon breast cancer histologies show wide variation in the application of BCT depending on the primary tumor. This suggests that an individualized approach in the use of BCT depending on histology should be used. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5400116 Mon, 07 Nov 2011 05:00:00 +0100 5400116 Peri‐operative chemotherapy for resectable colorectal liver metastasis: Does timing of systemic therapy matter? http://www.medworm.com/index.php?rid=5400115&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22133 ConclusionPre‐operative chemotherapy was associated with a trend toward increased morbidity among patients undergoing a major hepatic resection. Receipt of pre‐operative chemotherapy was associated with neither an advantage nor disadvantage in terms of long‐term survival. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5400115 Mon, 07 Nov 2011 05:00:00 +0100 5400115 A prognostic model to predict outcome of patients failing to achieve pathological complete response after anthracycline‐containing neoadjuvant chemotherapy for breast cancer http://www.medworm.com/index.php?rid=5400114&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22140 ConclusionOur prognostic model could easily discriminate patients with different risks of experiencing an event or death, which could allow physicians to tailor treatment strategies specifically and individually. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5400114 Mon, 07 Nov 2011 05:00:00 +0100 5400114 Identification of the a kinase anchor protein 12 (AKAP12) gene as a candidate tumor suppressor of hepatocellular carcinoma http://www.medworm.com/index.php?rid=5400120&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22135 ConclusionsThe current data suggest that AKAP12 is downregulated in cancer tissues through promoter hypermethylation, and may have a role as a candidate tumor suppressor gene for HCC. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5400120 Thu, 03 Nov 2011 04:00:00 +0100 5400120 The changing landscape of axillary surgery: Which breast cancer patients may still benefit from complete axillary lymph node dissection? http://www.medworm.com/index.php?rid=5360037&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22131 ConclusionA SLN+ biopsy by FS predicts the presence of NSLN metastases and, in combination with other factors, may justify immediate CALND. CALND may, however, be avoided in selected low‐risk SLN+ patients. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5360037 Mon, 31 Oct 2011 00:20:27 +0100 5360037 Atypical fibroxanthoma: Clinicopathologic determinants for recurrence and implications for surgical management http://www.medworm.com/index.php?rid=5346966&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22128 ConclusionsWhile the majority of AFX presentations are benign, there is a real possibility of metastatic spread. Invasion beyond the dermis and a rapid rate of recurrence are suggestive of a more aggressive clinical course. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5346966 Wed, 26 Oct 2011 05:45:37 +0100 5346966 Perioperative and long‐term results of laparoscopic spleen‐preserving distal pancreatectomy with or without splenic vessels conservation: A retrospective analysis http://www.medworm.com/index.php?rid=5346968&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22117 ConclusionLaparoscopic spleen‐preserving distal pancreatectomy is feasible. A moderate risk of postoperative splenic infarction has to be taken into account, and the formation of perigastric varices may be interpreted as a paraphysiologic phenomenon, especially after splenic vessels resection. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5346968 Mon, 24 Oct 2011 04:00:00 +0100 5346968 Elevated high‐sensitivity C‐reactive protein, a marker of advanced stage gastric cancer and postgastrectomy disease recurrence http://www.medworm.com/index.php?rid=5346967&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22129 ConclusionElevated preoperative hs‐CRP levels in gastric cancer patients are clinically significant indicators of advanced stage and postoperative disease recurrence. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5346967 Mon, 24 Oct 2011 04:00:00 +0100 5346967 Isolated limb perfusion with TNF‐alpha and melphalan for distal parts of the limb in soft tissue sarcoma patients http://www.medworm.com/index.php?rid=5335218&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22121 ConclusionWith a limb salvage rate of 87%, TM‐ILP is an effective treatment modality in patients with distal STS. In all patients with an indication for amputation surgery due to an STS in the distal part of the limb, TM‐ILP should be considered. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5335218 Sat, 22 Oct 2011 00:50:04 +0100 5335218 Oncofetal protein, IMP‐3, a potential marker for prediction of postoperative peritoneal dissemination in gastric adenocarcinoma http://www.medworm.com/index.php?rid=5335221&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22108 ConclusionsIMP‐3 expression in primary gastric tumors was an independent poor prognostic factor. IMP‐3 mRNA expression in peritoneal lavage fluid was a predictor of recurrence after surgery in gastric cancer and a marker of poor prognosis. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5335221 Wed, 19 Oct 2011 04:00:00 +0100 5335221 Post‐radiation sarcomas. Clinical outcome of 52 Patients http://www.medworm.com/index.php?rid=5335220&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22122 ConclusionsPrognosis of post‐radiation sarcomas is poor; the type of the sarcomas is the only significant variable for survival. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5335220 Wed, 19 Oct 2011 04:00:00 +0100 5335220 A phase I/II clinical trial of preoperative short‐course carbon‐ion radiotherapy for patients with squamous cell carcinoma of the esophagus http://www.medworm.com/index.php?rid=5335219&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22127 ConclusionsCIR showed strong local tumor control and is highly effective as a neoadjuvant therapy without severe adverse events. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5335219 Wed, 19 Oct 2011 04:00:00 +0100 5335219 Liver‐directed therapy for neuroendocrine neoplasm hepatic metastasis prolongs survival following progression after initial surgery http://www.medworm.com/index.php?rid=5323743&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22114 ConclusionA multimodality approach towards treatment of disease progression as shown in this study that includes repeat surgery or radioembolization has been shown to achieve a superior outcome in the setting of disease progression/recurrence. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5323743 Tue, 18 Oct 2011 00:54:47 +0100 5323743 Efficacy of pre‐operative chemotherapy with docetaxel, cisplatin, and S‐1 (DCS therapy) and curative resection for gastric cancer with pathologically positive para‐aortic lymph nodes http://www.medworm.com/index.php?rid=5323751&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22125 ConclusionMultimodal therapy comprising combined pre‐operative DCS therapy and gastrectomy with PAND was extremely effective and feasible for advanced gastric cancer with PAN metastasis. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5323751 Mon, 17 Oct 2011 04:00:00 +0100 5323751 Pretreatment risk factors for multiple gastric cancer and missed lesions http://www.medworm.com/index.php?rid=5323750&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22124 ConclusionPhysicians should keep pretreatment risk factors for MGC in mind to avoid missing a synchronous lesion. Meticulous examination is required after a detection of large‐sized main lesion. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5323750 Mon, 17 Oct 2011 04:00:00 +0100 5323750 Survival impact of malignant pancreatic neuroendocrine and islet cell neoplasm phenotypes http://www.medworm.com/index.php?rid=5323749&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22118 ConclusionsWhen controlled for other established prognostic parameters, histopathologic subtype assignment of pancreatic ICTs affects survival prediction. Resection is associated with superior survival for all tumor types. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5323749 Mon, 17 Oct 2011 04:00:00 +0100 5323749 Increased expression of fibroblastic growth factor receptor 2 is correlated with poor prognosis in patients with breast cancer http://www.medworm.com/index.php?rid=5323748&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22120 ConclusionsHigh FGFR2 expression is correlated with poor OS and DFS in breast cancer patients. It could be a biomarker for poor prognosis. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5323748 Mon, 17 Oct 2011 04:00:00 +0100 5323748 TS and DPD mRNA levels on formalin‐fixed paraffin‐embedded specimens as predictors for distant recurrence of rectal cancer treated with preoperative chemoradiotherapy http://www.medworm.com/index.php?rid=5323747&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22123 ConclusionsHigh TS and DPD mRNA levels on FFPE specimens may predict distant recurrence of rectal cancer treated with 5‐FU‐based preoperative CRT followed by surgery. Expression analysis of 5‐FU metabolizing enzyme in residual cancer may be useful for treatment stratification and clinical management in these patients. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5323747 Mon, 17 Oct 2011 04:00:00 +0100 5323747 Targeting the proteasome as a promising therapeutic strategy in thyroid cancer http://www.medworm.com/index.php?rid=5323746&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22113 ConclusionProteasome inhibition is effective in reducing cell growth and inducing apoptosis of ATC in vitro and inhibiting tumor growth and vascularity in vivo. However, the impact on nuclear transcription remains controversial. Clinical evaluation of bortezomib treatment in ATC is warranted. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5323746 Mon, 17 Oct 2011 04:00:00 +0100 5323746 The role of preoperative neck ultrasounds to assess lymph nodes in patients with suspicious or indeterminate thyroid nodules http://www.medworm.com/index.php?rid=5323745&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22115 ConclusionThyroid nodule microcalcifications on ultrasound and category of FNAB appear to be the best predictors of metastatic disease. Because the surgical approach was altered in only a few patients, further analysis is needed to delineate whether performing cervical ultrasound for suspicious/indeterminate nodules is cost effective. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5323745 Mon, 17 Oct 2011 04:00:00 +0100 5323745 Adding surgery as a complementary approach to radioiodine therapy in patients of differentiated thyroid carcinoma with large solitary flat bone metastases: the unresolved issues http://www.medworm.com/index.php?rid=5323744&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22116 (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5323744 Mon, 17 Oct 2011 04:00:00 +0100 5323744 The effect of postoperative pelvic irradiation after complete resection of metastatic rectal cancer http://www.medworm.com/index.php?rid=5304120&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22109 ConclusionsSurvival benefit of postoperative RTx in stage IV rectal cancer after complete removal of tumors was not apparent. RTx could be recommended for selected patients at high risk of local recurrence or for palliation of symptoms. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5304120 Wed, 12 Oct 2011 00:53:37 +0100 5304120 Prevention of lymphocele in female pelvic lymphadenectomy by a collagen patch coated with the human coagulation factors: A pilot study http://www.medworm.com/index.php?rid=5304121&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22110 ConclusionsIntraoperative application of TachoSil reduced rate of postoperative lymphocysts after PL, and it seems to provide a useful additional treatment option for reducing drainage volume and preventing lymphocele development after PL. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5304121 Mon, 10 Oct 2011 04:00:00 +0100 5304121 Multidisciplinary management of malignant pleural effusion http://www.medworm.com/index.php?rid=5273294&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22100 AbstractApproximately 50% of patients with metastatic disease develop a malignant pleural effusion (MPE). Prompt clinical evaluation and treatment to achieve successful palliation are the main goals of management of MPE. Optimal treatment is still controversial and there is no universal standard approach. Management options include observation, thoracentesis, indwelling pleural catheter (IPC) or chest tube placement, pleurodesis, and surgical pleurectomy. The treatment for each patient should be based on symptoms, general condition, and life expectancy. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5273294 Sat, 01 Oct 2011 04:00:00 +0100 5273294 Kyphoplasty in patients with multiple myeloma a retrospective comparative pilot study http://www.medworm.com/index.php?rid=5273296&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22101 ConclusionAdditional kyphoplasty was more effective than additional radiation or systemic therapy in terms of pain relief, reduction of pain associated disability and reduction of fracture incidence of the entire lumbar and thoracic spine. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5273296 Thu, 29 Sep 2011 04:00:00 +0100 5273296 Stereotactic body radiation therapy in hepatocellular carcinoma and cirrhosis: Evaluation of radiological and pathological response http://www.medworm.com/index.php?rid=5273295&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22104 ConclusionSBRT achieves total or partial radiological response in 37% of patients and total or partial pathological response in 37% of patients with early HCC in the setting of cirrhosis. SBRT may be a safe and effective alternative for local tumor control in patients with HCC and cirrhosis awaiting OLT. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5273295 Thu, 29 Sep 2011 04:00:00 +0100 5273295 Comparison of surgical outcomes between endoscopic and robotic thyroidectomy http://www.medworm.com/index.php?rid=5260210&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22106 ConclusionRobotic thyroidectomy was lengthier in duration than endoscopic thyroidectomy, more costly, and associated with increased postoperative drainage with no improvement in oncologic outcomes or complication rates. Therefore our data do not support any advantage of robotic surgery over endoscopic surgery. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5260210 Thu, 29 Sep 2011 00:51:02 +0100 5260210 Potent antitumour activity of the combination of HSV‐TK and endostatin armed oncolytic adeno‐associated virus for bladder cancer in vitro and in vivo http://www.medworm.com/index.php?rid=5260213&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22107 ConclusionsWe concluded that the inhibition of angiogenesis using Endostatin gene transfer, together with the cytotoxicity HSV‐TK gene therapy, resulted in a significant antitumour effect compared to the single gene based therapy in BTCC. The results warrant further development of the combination gene therapy, and suggest that this approach, directed towards systemic efficiency, could be used as an additional treatment for human BTCC. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5260213 Tue, 27 Sep 2011 04:00:00 +0100 5260213 Targeting integrins and enhanced permeability and retention (EPR) effect for optical imaging of oral cancer http://www.medworm.com/index.php?rid=5260212&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22102 ConclusionThis study demonstrates the feasibility of optical imaging of oral squamous cell carcinoma based on targeting of αvβ3 integrins and the EPR effect. Once these NIR fluorescence agents become available for clinical testing, optical image‐guided surgery could reduce residual disease after oral cancer surgery. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5260212 Tue, 27 Sep 2011 04:00:00 +0100 5260212 Ten‐year survival of esophageal cancer after an en‐bloc esophagectomy http://www.medworm.com/index.php?rid=5260211&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22096 ConclusionPatients with locally advanced disease, managed by a multidisciplinary treatment strategy, achieved a similar long‐term survival to patients with early disease (stadium I + II). J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5260211 Tue, 27 Sep 2011 04:00:00 +0100 5260211 Meta‐analysis of laparoscopy‐assisted distal gastrectomy with D2 lymph node dissection for gastric cancer http://www.medworm.com/index.php?rid=5250372&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22098 ConclusionsCompared with ODG, LADG with D2 dissection has the advantages of minimal invasion, faster recovery, and fewer complications, and it can achieve the same degree of radicality and short‐term prognosis as ODG. The drawbacks are that the operating time is slightly longer and long‐term prognosis is not clear. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5250372 Sun, 25 Sep 2011 08:54:49 +0100 5250372 Primary liver cancer presenting as pyogenic liver abscess: Characteristics, diagnosis, and management http://www.medworm.com/index.php?rid=5250375&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22103 ConclusionsElevated AFP and CA19‐9 could suggest HCC and IHCC in patients with symptoms/signs typical of PLA. Contrast‐enhanced computed tomography could be helpful in patients with normal AFP and CA19‐9. Making an accurate and early diagnosis and seizing the opportunity of surgery are essential to improve the management strategies of patients with PLC mimicking PLA. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5250375 Thu, 22 Sep 2011 04:00:00 +0100 5250375 Impact of perineal pseudocontinent colostomy on perineal wound healing after abdominoperineal resection http://www.medworm.com/index.php?rid=5250374&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22105 ConclusionsPPC accelerates perineal wound healing after APR without decreasing the overall perineal complication rate. J. Surg. Oncol © 2011 Wiley Periodicals, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5250374 Thu, 22 Sep 2011 04:00:00 +0100 5250374 A retrospective study of surgical treatment of chronic radiation enteritis http://www.medworm.com/index.php?rid=5236869&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22099 ConclusionsSurgery is justified for patients with bowel obstruction or fistula after CRE. A comprehensive perioperative management, especially perioperative nutrition therapy was important for the success of the surgery. J. Surg. Oncol © 2011 Wiley‐Liss, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5236869 Wed, 21 Sep 2011 17:36:48 +0100 5236869 Differential expression of sprouty genes in hepatocellular carcinoma http://www.medworm.com/index.php?rid=5236871&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22095 ConclusionThis study demonstrates that Sprouty genes are differentially expressed in HCC and might provide some insight into their roles in HCC carcinogenesis. J. Surg. Oncol © 2011 Wiley‐Liss, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5236871 Mon, 19 Sep 2011 04:00:00 +0100 5236871 High phosphorylated 4E‐binding protein 1 expression after chemoradiotherapy is a predictor for locoregional recurrence and worse survival in esophageal squamous cell carcinoma patients http://www.medworm.com/index.php?rid=5236870&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22097 Conclusion High p‐4E‐BP1 expression after CRT is a predictor for LR and worse survival in esophageal SCC patients. J. Surg. Oncol © 2011 Wiley‐Liss, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5236870 Mon, 19 Sep 2011 04:00:00 +0100 5236870 Axillary reverse mapping using a fluorescence imaging system in breast cancer http://www.medworm.com/index.php?rid=5207979&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22094 ConclusionsIt may be feasible to spare ARM nodes during ALND in patients with positive SLN. J. Surg. Oncol © 2011 Wiley‐Liss, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5207979 Mon, 12 Sep 2011 18:01:10 +0100 5207979 Cutaneous apocrine adenocarcinoma: Defining epidemiology, outcomes, and optimal therapy for a rare neoplasm http://www.medworm.com/index.php?rid=5207981&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22023 ConclusionsCutaneous apocrine adenocarcinoma is a rare neoplasm. Excision is standard treatment. The most important predictor of survival in localized disease is lymph node status; therefore, sentinel lymph node biopsy could be considered in management of this disease. J. Surg. Oncol © 2011 Wiley‐Liss, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5207981 Mon, 12 Sep 2011 04:00:00 +0100 5207981 Clinical decision‐making and implementation challenges with the AJCC VII staging system for colorectal carcinoma http://www.medworm.com/index.php?rid=5207980&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22086 (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5207980 Mon, 12 Sep 2011 04:00:00 +0100 5207980 Anti‐cancer agents for breast cancer treatment during pregnancy http://www.medworm.com/index.php?rid=5196125&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.21951 (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5196125 Tue, 06 Sep 2011 17:45:05 +0100 5196125 Response to letter to the editor http://www.medworm.com/index.php?rid=5196124&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.21950 (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5196124 Tue, 06 Sep 2011 17:45:04 +0100 5196124 Long‐term results and prognostic factors of gastric cancer patients with only positive peritoneal lavage cytology http://www.medworm.com/index.php?rid=5196121&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22091 ConclusionsA Borrmann type IV carcinoma may be the candidates for intraperitoneal chemotherapy among advanced gastric cancer patients. J. Surg. Oncol © 2011 Wiley‐Liss, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5196121 Tue, 06 Sep 2011 17:42:43 +0100 5196121 B lymphocytes as effector cells in the immunotherapy of cancer http://www.medworm.com/index.php?rid=5196123&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22093 AbstractOver the years, the role of B cells in the host immune response to malignancy has been overshadowed by our focus on T cells. Nevertheless, B cells play important roles as antigen‐presenting cells and in the production of antibodies. Furthermore, B cells can function as effector cells that mediate tumor destruction on their own. This review will highlight the various functions of B cells that are involved in the host response to tumor. J. Surg. Oncol. © 2011 Wiley‐Liss, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5196123 Mon, 05 Sep 2011 23:00:00 +0100 5196123 Survival analysis of gastric cancer patients with tumor thrombus in the portal vein http://www.medworm.com/index.php?rid=5196122&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22083 ConclusionsPVTT originating from gastric cancer was a poor prognostic factor and the median survival from PVTT was different according to several clinical factors. J. Surg. Oncol. © 2011 Wiley‐Liss, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5196122 Mon, 05 Sep 2011 23:00:00 +0100 5196122 Clinical significance of pathologic subtype in curatively resected ampulla of vater cancer http://www.medworm.com/index.php?rid=5183440&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22090 ConclusionsAn advanced T stage, nodal metastasis, poor differentiation, and the pancreaticobiliary type were found to be independent predictors of recurrence after curative resection of ampullary carcinoma by multivariate analysis. In addition, the pancreatobiliary type tended to present in a more advanced T stage and more frequently with regional lymph node involvement and perineural invasion than the intestinal type. Furthermore, CEA level and lymph node metastasis were found to be independent predictors of recurrence for the intestinal and pancreatobiliary types, respectively. J. Surg. Oncol © 2011 Wiley‐Liss, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5183440 Wed, 31 Aug 2011 23:00:00 +0100 5183440 Implementation of educational video improves patient understanding of basic breast cancer concepts in an undereducated county hospital population http://www.medworm.com/index.php?rid=5183445&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22046 ConclusionsImplementation of an educational video significantly improved understanding of breast cancer concepts in an undereducated population. J. Surg. Oncol. © 2011 Wiley‐Liss, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5183445 Tue, 30 Aug 2011 23:00:00 +0100 5183445 Gastric cancer: Biology and clinical manifestations in Israel http://www.medworm.com/index.php?rid=5183444&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22078 ConclusionThere do not appear to be any major differences in the biology or clinical manifestations of GC in Israel. Western recommendations for diagnosis and treatment of GC may therefore be applied to the Israeli patient population. J. Surg. Oncol. © 2011 Wiley‐Liss, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5183444 Tue, 30 Aug 2011 23:00:00 +0100 5183444 Controversies in parathyroid surgery: The quest for a “mini” unilateral parathyroid operation seems to have gone too far http://www.medworm.com/index.php?rid=5183443&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22040 (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5183443 Tue, 30 Aug 2011 23:00:00 +0100 5183443 Intraperitoneal docetaxel combined with S‐1 for advanced gastric cancer with peritoneal dissemination http://www.medworm.com/index.php?rid=5183442&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22057 ConclusionThis study indicated that the NIPS combined with surgery was highly active and well tolerated by advanced gastric cancer patients with PC. J. Surg. Oncol © 2011 Wiley‐Liss, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5183442 Tue, 30 Aug 2011 23:00:00 +0100 5183442 Clinicopathologic variables predicting tumor response to neoadjuvant chemotherapy in patients with locally advanced gastric cancer http://www.medworm.com/index.php?rid=5183441&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22085 ConclusionsThis study suggests that both tumor differentiation and tumor size is the most important clinical predicator of pathologic tumor response, it may be of benefit in the selection of treatment options in locally advanced gastric cancer. J. Surg. Oncol © 2011 Wiley‐Liss, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5183441 Tue, 30 Aug 2011 23:00:00 +0100 5183441 Prognostic significance of high podoplanin expression after chemoradiotherapy in esophageal squamous cell carcinoma patients http://www.medworm.com/index.php?rid=5183450&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22068 ConclusionTumor PP immunoreactivity in conjunction with CRM status are useful markers to identify aggressive post‐CRT treated ypT3N0 stage esophageal SCC. J. Surg. Oncol © 2011 Wiley‐Liss, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5183450 Mon, 29 Aug 2011 23:00:00 +0100 5183450 Prognostic significance of intraoperative chemotherapy and extensive lymphadenectomy in patients with node‐negative gastric cancer http://www.medworm.com/index.php?rid=5183449&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22089 ConclusionsIn pN0 gastric cancers, prognostic factors differed significantly between early stage and advanced stage. For patients with pT3, besides curative gastrectomy and postoperative chemotherapy, it might be beneficial to perform intraoperative chemotherapy and extensive lymphadenectomy. J. Surg. Oncol © 2011 Wiley‐Liss, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5183449 Mon, 29 Aug 2011 23:00:00 +0100 5183449 Down‐regulated SPARCL1 is associated with clinical significance in human gastric cancer http://www.medworm.com/index.php?rid=5183448&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22025 ConclusionsOur study revealed the clinical significance of SPARCL1 expression, providing a basis that the loss of SPARCL1 is a negative event in GC progression and prognosis. Furthermore, SPARCL1 protein might be considered to be a potential differentiation marker. J. Surg. Oncol. © 2011 Wiley‐Liss, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5183448 Mon, 29 Aug 2011 23:00:00 +0100 5183448 Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy for patients with peritoneal carcinomatosis secondary to urachal adenocarcinoma http://www.medworm.com/index.php?rid=5183447&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22081 ConclusionsUrachal adenocarcinoma with peritoneal dissemination is an aggressive, rare disease, which is uniformly fatal. In our experience, CRS followed by HIPEC with Mitomycin C may increase patient survival and palliation, although further treatment improvements are clearly required. J. Surg. Oncol. © 2011 Wiley‐Liss, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5183447 Mon, 29 Aug 2011 23:00:00 +0100 5183447 RUNX3 methylation as a predictor for disease progression in patients with non‐muscle‐invasive bladder cancer http://www.medworm.com/index.php?rid=5183446&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22087 ConclusionsRUNX3 methylation status predicted the risk of NMIBC progression independently of tumor stage. In conjunction with tumor grade, RUNX3 methylation status in patients with NMIBC strongly predicts disease progression. J. Surg. Oncol © 2011 Wiley‐Liss, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5183446 Mon, 29 Aug 2011 23:00:00 +0100 5183446 Lymphatic vessel invasion detected by the D2‐40 monoclonal antibody is an independent prognostic factor in node‐negative esophageal squamous cell carcinoma http://www.medworm.com/index.php?rid=5161156&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22079 ConclusionsLVI detected by D2‐40 staining was an independent prognostic factor in patients with node‐negative ESCC. J. Surg. Oncol © 2011 Wiley‐Liss, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5161156 Sat, 27 Aug 2011 13:01:39 +0100 5161156 Poor prognostic factors in patients with stage I gastric cancer according to the seventh edition TNM classification: A comparative analysis of three subgroups http://www.medworm.com/index.php?rid=5161158&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22082 ConclusionsSurvival data support the accuracy of new TNM classification for stage I gastric cancer. Tumor stage, the presence of LBVI and PNI are important independent prognostic factors in stage I gastric cancer. J. Surg. Oncol © 2011 Wiley‐Liss, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5161158 Tue, 23 Aug 2011 23:00:00 +0100 5161158 Clinicopathological features and prognostic factors of gastric cancer patients aged 40 years or younger http://www.medworm.com/index.php?rid=5161157&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22084 ConclusionsGC tends to exhibit more aggressive tumor behavior in young patients than in old patients; however, the surgical survival of young and old patients was similar. Advanced nodal involvement (N3) is the most important independent prognostic factor in the young. J. Surg. Oncol © 2011 Wiley‐Liss, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5161157 Tue, 23 Aug 2011 23:00:00 +0100 5161157 Increased expression of insulin‐like growth factor‐1 receptor is correlated with tumor metastasis and prognosis in patients with osteosarcoma http://www.medworm.com/index.php?rid=5161164&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22077 ConclusionsIGF‐1R is an independent prognostic marker for osteosarcoma patients and increased expression of this molecular is correlated with metastasis of osteosarcoma. J. Surg. Oncol © 2011 Wiley‐Liss, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5161164 Sun, 21 Aug 2011 23:00:00 +0100 5161164 MiR‐142‐3p as a potential prognostic biomarker for esophageal squamous cell carcinoma http://www.medworm.com/index.php?rid=5161163&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22066 ConclusionThe main findings suggest that miR‐142‐3p is involved in the progression of ESCC and is a potential prognostic biomarker for ESCC. J. Surg. Oncol © 2011 Wiley‐Liss, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5161163 Sun, 21 Aug 2011 23:00:00 +0100 5161163 Is a level III dissection necessary for a positive sentinel lymph node in melanoma? http://www.medworm.com/index.php?rid=5161162&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22076 ConclusionsThe complication rate and regional recurrence rate for patients undergoing a level I/II ALND for a positive SLN are either lower than or on par with reported series of ALND for level I, II, and III dissections, suggesting that in this setting, the level III dissection may be of minimal benefit. J. Surg. Oncol © 2011 Wiley‐Liss, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5161162 Sun, 21 Aug 2011 23:00:00 +0100 5161162 The impact of recurrent laryngeal neuromonitoring on multi‐dimensional voice outcomes following thyroid surgery http://www.medworm.com/index.php?rid=5161161&cid=s_33654_6_f&fid=33654&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fjso.22063 ConclusionIn this study, recurrent laryngeal neuromonitoring did not appear to influence non‐RLN injury related VO as measured by a comprehensive multidimensional voice assessment. J. Surg. Oncol © 2011 Wiley‐Liss, Inc. (Source: Journal of Surgical Oncology) Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5161161 Sun, 21 Aug 2011 23:00:00 +0100 5161161