MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Journal of the American Academy of Dermatology' source. Sun, 21 Mar 2010 14:52:30 +0100 http://www.medworm.com/index.php?rid=3367414&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962210002306%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367414 Tue, 16 Mar 2010 14:28:18 +0100 3367414 http://www.medworm.com/index.php?rid=3367413&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS019096221000229X%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367413 Tue, 16 Mar 2010 14:28:18 +0100 3367413 http://www.medworm.com/index.php?rid=3367412&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962210002288%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367412 Tue, 16 Mar 2010 14:28:18 +0100 3367412 http://www.medworm.com/index.php?rid=3367411&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962210002264%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367411 Tue, 16 Mar 2010 14:28:18 +0100 3367411 http://www.medworm.com/index.php?rid=3367410&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962210002276%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367410 Tue, 16 Mar 2010 14:28:18 +0100 3367410 http://www.medworm.com/index.php?rid=3367409&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS019096220801356X%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367409 Tue, 16 Mar 2010 14:28:17 +0100 3367409 http://www.medworm.com/index.php?rid=3367408&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962208013856%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367408 Tue, 16 Mar 2010 14:28:15 +0100 3367408 http://www.medworm.com/index.php?rid=3367407&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209009578%2Fabstract%3Frss%3Dyes The Pantheon in Rome survives today as one of the triumphs of Western architecture. It was erected between 120 and 124 AD by the Emperor Hadrian as a temple dedicated to the multiple gods of Rome. An eighteenth century depiction of it, in masterful perspective, by Giovanni Paolo Panini, now in the National Gallery of Art in Washington, DC graces the cover of this unique tribute to the “deities” of dermatology. It is fittingly entitled Pantheon der Dermatologie. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367407 Tue, 16 Mar 2010 14:28:14 +0100 3367407 http://www.medworm.com/index.php?rid=3367406&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS019096220801459X%2Fabstract%3Frss%3Dyes To the Editor: A 1-year-old white male with a 6-month history of “raised bumps” overlying the dorsal surface of his neck was brought to our dermatology clinic for evaluation. An agminated patch of white papules was identified on the suboccipital neck (). Nuchal ultrasound was unremarkable. A 3-mm punch biopsy demonstrated spindle cell proliferation within the papillary dermis, without significant atypia (, A). Vascularity was slightly increased. The overlying epidermis was unremarkable. Laboratory tests for Ulex europaeus, S-100, CD68, muscle-specific actin, and smooth muscle actin were negative. The spindle cells and visualized vascular structures stained strongly positive for CD34 (, B). After a thorough Web-based literature search, we were unable to find any reports of CD34+ stainin... Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367406 Tue, 16 Mar 2010 14:28:14 +0100 3367406 http://www.medworm.com/index.php?rid=3367405&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962208014321%2Fabstract%3Frss%3Dyes To the Editor: A 57-year-old African American male with a history of a seizure disorder caused by a traumatic head injury presented to the emergency department with a recent onset of multiple pustular lesions that started on his face and spread to his trunk and upper extremities. He had presented to the same emergency department 5 days earlier in status epilepticus. He was treated with 1 g phenytoin for the first time in addition to increased doses of his other medicines (lorazepam and levetiracetam). His seizure resolved and he was discharged 2 days later on increased doses of levetiracetam and valproic acid. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367405 Tue, 16 Mar 2010 14:28:14 +0100 3367405 http://www.medworm.com/index.php?rid=3367404&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962208013108%2Fabstract%3Frss%3Dyes To the Editor: Nutritional deficiency, a prevalent problem worldwide, remains rare in developed countries. In the United States, acquired nutritional deficiencies have been reported in patients with anorexia nervosa, malabsorption syndromes, those on long-term parenteral nutrition, and patients with food allergies. Given the significant morbidity and sometimes mortality associated with certain nutritional deficiencies, their prompt recognition, diagnosis, and treatment by clinicians is of great importance. Many nutritional deficiencies have classic cutaneous presentations that are valuable clinical diagnostic tools. However, combined nutritional deficiencies often put forth a mixed clinical picture easily mistaken for another condition. There is a paucity of reports of cutaneous presentati... Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367404 Tue, 16 Mar 2010 14:28:14 +0100 3367404 http://www.medworm.com/index.php?rid=3367403&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962208012462%2Fabstract%3Frss%3Dyes To the Editor: Current molecular diagnostics have characterized many new autoimmune bullous diseases that traditional descriptive dermatology would not have been able to define. Herein we report a case of refractory oral ulcers with immunoblots that were confusing, causing difficulty in making a definitive diagnosis. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367403 Tue, 16 Mar 2010 14:28:14 +0100 3367403 http://www.medworm.com/index.php?rid=3367402&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962208012061%2Fabstract%3Frss%3Dyes To the Editor: Myxoinflammatory fibroblastic sarcoma (MIFS) is a slow growing, low grade tumor reported as a soft tissue tumor affecting the distal extremities. It was first described in 1998 by Meis-Kindblom and Kindblom and Montgomery et al. Although it was described by different names—acral MIFS and inflammatory myxohyaline tumor of distal extremities with virocyte or Reed-Sternberg–like cells—it described the same entity of histologic features. The reported histologic similarities included numerous inflammatory cells (plasma cells, granulocytes, eosinophils, and lymphocytes), fibrosis, and scattered, large, bizarre tumor cells resembling Reed-Sternberg–like cells in an abundant myxoid extracellular matrix. Clinically, it is described in all age groups (4-91 yrs of age), occurs... Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367402 Tue, 16 Mar 2010 14:28:14 +0100 3367402 http://www.medworm.com/index.php?rid=3367401&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS019096220901247X%2Fabstract%3Frss%3Dyes To the Editor: We read with interest the article by Rose et al in the August 2009 issue of the Journal. Ultraviolet B light phototherapy (UVB) is generally considered the safest form of systemic psoriasis therapy in pregnancy. We commend the authors for creating a study to examine the photodegradation of serum folate after exposure to narrowband UVB (nbUVB), given that folate deficiency in the first trimester of pregnancy could predispose to the development of neural tube defects. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367401 Tue, 16 Mar 2010 14:28:14 +0100 3367401 http://www.medworm.com/index.php?rid=3367400&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209012432%2Fabstract%3Frss%3Dyes To the Editor: The International Sentinel Node Society (ISNS) opinion, that sentinel node biopsy (SNB) “is standard of care,” is not supported by clinical evidence and warrants scrutiny. Their commentary contradicts recent multidisciplinary Australian guidelines that state that “Patients with a melanoma greater than 1.0 mm in thickness be given the opportunity to discuss SNB to provide staging and prognostic information” but deliberately do not state that SNB should be considered standard of care. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367400 Tue, 16 Mar 2010 14:28:13 +0100 3367400 http://www.medworm.com/index.php?rid=3367399&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209012286%2Fabstract%3Frss%3Dyes To the Editor: I read with interest the article by Nijsten et al in the January 2009 issue of the Journal that describes three minimally invasive techniques in the treatment of saphenous varicose veins: foam sclerotherapy, endovenous laser therapy, and radiofrequency ablation. Another procedure—the 3S saphenectomy (the 3S technique)—should be added to theses techniques. The 3S technique associates the surgical sectioning and sclerotherapy of saphenous veins under local anesthesia. It has been developed in France mainly by Vin et al. Many angiophlebologists learned this technique during the educational program of the European School of Phlebology in Paris. It is useful in the following instances: (1) when surgery is not recommended because of an advanced age and/or in case of a leg ul... Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367399 Tue, 16 Mar 2010 14:28:13 +0100 3367399 http://www.medworm.com/index.php?rid=3367398&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS019096220901216X%2Fabstract%3Frss%3Dyes To the Editor: We read with great interest the comprehensive review by Alikhan et al in the April 2009 issue of the Journal and would like to comment on our own recent findings regarding hidradenitis suppurativa (HS) and the Dermatology Life Quality Index (DLQI). (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367398 Tue, 16 Mar 2010 14:28:13 +0100 3367398 http://www.medworm.com/index.php?rid=3367397&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209010974%2Fabstract%3Frss%3Dyes To the Editor: Choosing appropriate, safe treatment for pregnant patients with psoriasis can be challenging. Although tumor necrosis factor–alfa (TNFα) antagonists are considered category B drugs according to the US Food and Drug Administration (FDA), Carter et al reported a disturbing association of infliximab and etanercept with congenital anomalies associated with the vertebral, anal, cardiovascular, tracheoesophageal, renal, limb (VACTERL) syndrome. In their review of more than 120000 adverse events of patients on TNFα antagonist therapy, they found 61 congenital anomalies occurring at higher than expected frequencies. No reports of congenital anomalies were reported in patients taking adalimumab; however, the database included entries only through 2005, which was relatively soon a... Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367397 Tue, 16 Mar 2010 14:28:13 +0100 3367397 http://www.medworm.com/index.php?rid=3367394&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962208009158%2Fabstract%3Frss%3Dyes We report herein a case of EBV-positive LELCS. An 82-year-old female presented with a red nodule on the right cheek. Histologically, the entire dermis was occupied by atypical tumor cell nests with dense lymphocytic infiltration. Neoplastic cells were strongly positive for cytokeratin 14 but were negative for cytokeratins 19 and 20. EBV genomes in neoplastic cells were detected by polymerase chain reaction analysis and in situ hybridization for EBV-encoded RNA, suggesting an association with EBV. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367394 Tue, 16 Mar 2010 14:28:12 +0100 3367394 http://www.medworm.com/index.php?rid=3367393&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209007294%2Fabstract%3Frss%3Dyes We present a report of a 63-year-old man with AIDS who was diagnosed with coexistent Kaposi sarcoma (KS), Cryptococcus neoformans, and Mycobacterium avium intracellulare in a single, solitary lesion. A literature review identified 11 cases of patients with AIDS and cutaneous lesions with co-existent KS and other infectious organisms. To our knowledge, this is the first report of coexistent KS, C neoformans, and M avium intracellulare in the same cutaneous lesion in a patient with AIDS. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367393 Tue, 16 Mar 2010 14:28:12 +0100 3367393 http://www.medworm.com/index.php?rid=3367390&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962210002513%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367390 Tue, 16 Mar 2010 14:28:12 +0100 3367390 http://www.medworm.com/index.php?rid=3367389&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962210001301%2Fabstract%3Frss%3Dyes Hossler EW. Caterpillars and moths. Part I. Dermatologic manifestations of encounters with Lepidoptera. J Am Acad Dermatol 2010;62:1-10. Hossler EW. Caterpillars and moths. Part II. Dermatologic manifestations of encounters with Lepidoptera. J Am Acad Dermatol 2010;62:13-28. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367389 Tue, 16 Mar 2010 14:28:12 +0100 3367389 http://www.medworm.com/index.php?rid=3367388&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962210000319%2Fabstract%3Frss%3Dyes Dialogues in Dermatology, a monthly audio program from the American Academy of Dermatology, contains discussions between dermatologists on timely topics. Commentaries from Dialogues Editor-in-Chief Jacqueline M. Junkins-Hopkins, MD, are provided after each discussion as a topic summary and are provided here as a special service to readers of the Journal of the American Academy of Dermatology. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367388 Tue, 16 Mar 2010 14:28:12 +0100 3367388 http://www.medworm.com/index.php?rid=3367386&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209006707%2Fabstract%3Frss%3Dyes Pyoderma gangrenosum is a rare and often painful skin disease that can be unpredictable in its response to treatment. There is currently no gold standard of treatment or published algorithm for choice of therapy. The majority of data comes from case studies that lack a standard protocol not only for treatment administration but also for the objective assessment of lesion response to a specific therapy. This review provides an update to the treatment of pyoderma gangrenosum with a particular focus on new systemic therapies. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367386 Tue, 16 Mar 2010 14:28:12 +0100 3367386 http://www.medworm.com/index.php?rid=3367385&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209009827%2Fabstract%3Frss%3Dyes Conclusions: Long-pulsed neodymium:yttrium-aluminium-garnet laser, together with topical benzoyl peroxide and clindamycin, is significantly more effective than topical benzoyl peroxide and clindamycin alone for the treatment of HS. Preliminary review of histopathology suggests the mechanism of action is destruction of the hair follicle. The overall success of the treatment in both clearing pre-existing lesions and preventing new eruptions, coupled with high patient satisfaction, makes the neodymium:yttrium-aluminium-garnet laser a promising treatment advance for this highly disabling condition. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367385 Tue, 16 Mar 2010 14:28:11 +0100 3367385 http://www.medworm.com/index.php?rid=3367384&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209009748%2Fabstract%3Frss%3Dyes Conclusion: The different flaps provide elegant local alternatives to second-intention healing and maximize cosmetic and functional results after matrix excision with narrow margins for longitudinal melanonychia. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367384 Tue, 16 Mar 2010 14:28:11 +0100 3367384 http://www.medworm.com/index.php?rid=3367381&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962210002501%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367381 Tue, 16 Mar 2010 14:28:11 +0100 3367381 http://www.medworm.com/index.php?rid=3367376&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962210002495%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367376 Tue, 16 Mar 2010 14:28:10 +0100 3367376 http://www.medworm.com/index.php?rid=3367374&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962210002483%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367374 Tue, 16 Mar 2010 14:28:10 +0100 3367374 http://www.medworm.com/index.php?rid=3367373&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209023123%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367373 Tue, 16 Mar 2010 14:28:10 +0100 3367373 http://www.medworm.com/index.php?rid=3367372&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209023111%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367372 Tue, 16 Mar 2010 14:28:10 +0100 3367372 http://www.medworm.com/index.php?rid=3367371&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209022920%2Fabstract%3Frss%3Dyes There are a number of systemic disorders that can manifest with urticarial skin lesions, including urticarial vasculitis, connective tissue diseases, hematologic diseases, and autoinflammatory syndromes. All of these conditions may enter into the differential diagnosis of ordinary urticaria. In contrast to urticaria, urticarial syndromes may manifest with skin lesions other than wheals, such as papules, necrosis, vesicles, and hemorrhages. Lesions may have a bilateral and symmetrical distribution; individual lesions have a long duration, and their resolution frequently leaves marks, such as hyperpigmentation or bruising. Moreover, systemic symptoms, such as fever, asthenia, and arthralgia, may be present. The most important differential diagnosis in this group is urticarial vasculitis, whi... Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367371 Tue, 16 Mar 2010 14:28:09 +0100 3367371 http://www.medworm.com/index.php?rid=3367370&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209022944%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367370 Tue, 16 Mar 2010 14:28:09 +0100 3367370 http://www.medworm.com/index.php?rid=3367369&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209022956%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367369 Tue, 16 Mar 2010 14:28:09 +0100 3367369 http://www.medworm.com/index.php?rid=3367368&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209022919%2Fabstract%3Frss%3Dyes Acute urticaria is self-limiting, and a cause can be identified in many patients. Chronic urticaria is a long lasting disease, and patients are commonly examined for an autoimmune origin and for associated diseases. Although the diagnosis of urticaria is straightforward in most patients, it may pose some difficulties at times and it may require a careful differential diagnosis with a number of conditions. Urticarial syndromes comprise both cutaneous and systemic disorders. Part I of this two-part series focuses on the clinical and histologic features that characterize common urticaria and on the cutaneous diseases that may manifest with urticarial lesions and must be considered in the differential diagnosis.Learning objectives: After completing the learning activity, participants should be... Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367368 Tue, 16 Mar 2010 14:28:09 +0100 3367368 http://www.medworm.com/index.php?rid=3367380&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209009402%2Fabstract%3Frss%3Dyes Conclusions: Sunscreens and antimicrobial agents were the most frequent allergens eliciting PACD, and there was a decrease in PACD caused by fragrances. The number of reactions to medications increased. This study also demonstrated that pesticides can be a cause of PACD. The detection of reactions to Fentichlor was unexpected and, although they have been attributed in some studies to cross-reactions to sulfanilamides and bithionol, such a robust association was not observed in this study. This study extends our experience of the changes in the allergens that elicit PACD to 20 years. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367380 Wed, 17 Feb 2010 00:00:00 +0100 3367380 http://www.medworm.com/index.php?rid=3273827&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS019096221000071X%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273827 Tue, 16 Feb 2010 14:09:41 +0100 3273827 http://www.medworm.com/index.php?rid=3273826&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962210000708%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273826 Tue, 16 Feb 2010 14:09:41 +0100 3273826 http://www.medworm.com/index.php?rid=3273825&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS019096221000068X%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273825 Tue, 16 Feb 2010 14:09:41 +0100 3273825 http://www.medworm.com/index.php?rid=3273824&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962210000691%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273824 Tue, 16 Feb 2010 14:09:41 +0100 3273824 http://www.medworm.com/index.php?rid=3273823&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962208011584%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273823 Tue, 16 Feb 2010 14:09:41 +0100 3273823 http://www.medworm.com/index.php?rid=3273822&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962208013157%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273822 Tue, 16 Feb 2010 14:09:41 +0100 3273822 http://www.medworm.com/index.php?rid=3273821&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209007282%2Fabstract%3Frss%3Dyes A 15-year-old healthy black female presented with persistent white spots that had been present since the patient was 4 years of age. Her father had a similar condition. The physical examination revealed scattered circinate hypopigmented to pink macules across her forehead (), neck, and back (). She also had unrelated hyperpigmented scars from a previous chicken pox infection. Shave biopsy specimens revealed coarse hypergranulosis and enlarged keratinocytes with pale blue cytoplasm (). (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273821 Tue, 16 Feb 2010 14:09:40 +0100 3273821 http://www.medworm.com/index.php?rid=3273820&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962210000721%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273820 Tue, 16 Feb 2010 14:09:40 +0100 3273820 http://www.medworm.com/index.php?rid=3273819&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS019096220900663X%2Fabstract%3Frss%3Dyes An 88-year-old white man presented to our department for the evaluation of multiple scalp lesions of relatively recent onset. There was no pertinent family history. He denied trauma to the area, ever having been diagnosed with an infection of the area caused by herpes simplex virus (HSV) or varicella zoster virus (VZV), and ever having received radiation therapy. The physical examination revealed multiple indurated, red, and slightly violaceous plaques and nodules on the scalp in a strikingly linear pattern. The collection of tumors covered a 9 cm × 3 cm area on the right forehead, frontal scalp, and parietal scalp (). There was no clinical lymphadenopathy. Review by a dermatopathologist yielded a diagnosis of malignant epithelioid neoplasm, and additional special stains were performed. I... Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273819 Tue, 16 Feb 2010 14:09:40 +0100 3273819 http://www.medworm.com/index.php?rid=3273818&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209005295%2Fabstract%3Frss%3Dyes A 57-year-old white female presented with small, scattered patches of alopecia. She had a history of metastatic ductal breast cancer, and 2 months before her visit had finished three cycles of adriamycin and cyclophosphamide followed by three cycles of docetaxol and cyclophosphamide. Her current medications included anastrazole and omeprazole. She denied any areas of alopecia before treatment, and she lost all of her hair during chemotherapy. Following chemotherapy, she noticed that some areas of her scalp remained bald. She denied pruritus, pain, and flaking. She had not attempted to treat the condition. She denied any personal or family history of autoimmune disorders. Her review of systems was negative. A physical examination revealed many scattered, 1- to 2-cm, white, atrophic patches ... Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273818 Tue, 16 Feb 2010 14:09:40 +0100 3273818 http://www.medworm.com/index.php?rid=3273817&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209005301%2Fabstract%3Frss%3Dyes Learning objectives: At the conclusion of this learning activity, physician participants should be able to assess their own diagnostic and patient management skills and use the results of this exercise to help determine personal learning needs that can be addressed through subsequent CME involvement. Instructions for claiming CME credit appear in the front advertising section. See last page of Contents for page number.Instructions: In answering each question, refer to the specific directions provided. Because it is often necessary to provide information occurring later in a series that give away answers to earlier questions, please answer the questions in each series in sequence. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273817 Tue, 16 Feb 2010 14:09:40 +0100 3273817 http://www.medworm.com/index.php?rid=3273816&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209002618%2Fabstract%3Frss%3Dyes To the Editor: Cetuximab is an epidermal growth factor receptor (EGFR)-inhibitor approved by the US Food and Drug Administration (FDA) and the European Medicines Agency (EMEA) for metastatic colorectal carcinoma and head and neck squamous cell carcinoma. More recently, a few authors have reported good responses with cetuximab in the treatment of recurrent squamous cell skin cancer in a palliative setting. The safety profile for these drugs is unique, with virtually no hematologic toxicity but frequent cutaneous side effects, which may cause serious discomfort and be disabling. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273816 Tue, 16 Feb 2010 14:09:40 +0100 3273816 http://www.medworm.com/index.php?rid=3273815&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS019096220900259X%2Fabstract%3Frss%3Dyes To the Editor: A 31-year old healthy woman presented with a painful, 6-mm ulcerated subcutaneous nodule on the ventral surface of her left hand (). A similar lesion had developed at a different site on the left palm a few months previously. Histologic examination of the current lesion revealed acanthosis with focal epidermal and dermal necrosis extending into the reticular dermis. There was a dense, superficial and deep, perivascular, and band-like predominantly lymphocytic infiltrate with scattered, enlarged mononuclear cells characterized by hyperchromatic nuclei and prominent nucleoli (, A and B). The latter cells were reactive for CD30 by immunohistochemistry (, C), consistent with lymphomatoid papulosis. Over the next 2 years, the patient had recurrent episodes of similar lesions on t... Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273815 Tue, 16 Feb 2010 14:09:36 +0100 3273815 http://www.medworm.com/index.php?rid=3273814&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209002540%2Fabstract%3Frss%3Dyes To the Editor: Unilateral nevoid telangiectasia (UNT) is a vascular dermatosis of obscure etiology that is characterized by linearly arranged telangiectasias in a unilateral or Blaschkoid pattern. The disorder is frequently found in the upper extremities and/or shoulders. Its histopathology is characterized by dilated capillaries in the papillary dermis and mid-dermis. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273814 Tue, 16 Feb 2010 14:09:36 +0100 3273814 http://www.medworm.com/index.php?rid=3273813&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209002436%2Fabstract%3Frss%3Dyes To the Editor: A 66-year-old man presented with a 2-month history of a slowly enlarging right axillary lymph node. Four years earlier, symmetric papillomatosis and darkening of the axillae and neck had developed (). The patient did not have diabetes and had a history of melanoma excised from his back 17 years earlier. The node was resected (); a skin biopsy specimen showed acanthosis nigricans, with acanthosis, papillomatosis, hyperkeratosis, and increased dermal pigmentation (). Histologic () and immunohistochemical analyses of the axillary node were consistent only with an unspecified sarcoma. Melanoma was excluded by immunohistochemistry. Computed tomography scans revealed metastases in multiple lymph nodes, the liver, and the spleen; the primary tumor was not found. (Source: Journal of... Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273813 Tue, 16 Feb 2010 14:09:36 +0100 3273813 http://www.medworm.com/index.php?rid=3273812&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209001431%2Fabstract%3Frss%3Dyes To the Editor: We previously reported that alopecia areata (AA), an autoimmune disease targeting the hair follicle causing hair loss, had a 55% concordance rate in monozygotic twins, suggesting both genetic and environmental triggers. Recently, we also reported a possible association between Epstein–Barr virus (EBV)-related mononucleosis and onset of AA in 12 young individuals. To further study the role of genes versus environment in the pathogenesis of AA, we examined concordance rates for AA and exposure to EBV by IgG serology in a new cohort of twins from the National Alopecia Areata Registry. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273812 Tue, 16 Feb 2010 14:09:36 +0100 3273812 http://www.medworm.com/index.php?rid=3273811&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS019096220900142X%2Fabstract%3Frss%3Dyes To the Editor: A 44-year-old man was referred to our department with a 1-month history of lesions on his glans penis. A clinical examination revealed two well defined, orange-yellow to skin-colored, dome-shaped, smooth, 5- to 7-mm asymptomatic papules (). General laboratory screening, including lipid levels, renal and liver function tests, and a complete blood count, were within normal limits. A biopsy specimen from one of the papules showed a dermal infiltrate composed of macrophages, neutrophils, lymphocytes, and fibroblasts, along with foam cells and Touton giant cells (). A diagnosis of xanthogranuloma (XG) was made. An ophthalmology examination revealed no abnormalities. Two months after the biopsy, the papules disappeared spontaneously and no obvious relapse has been noted. (Source: ... Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273811 Tue, 16 Feb 2010 14:09:36 +0100 3273811 http://www.medworm.com/index.php?rid=3273810&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209008342%2Fabstract%3Frss%3Dyes To the Editor: There is a shortage of academic dermatologists in the United States. Although dermatology resident applicants have strong academic and research backgrounds, many lose interest in academic careers. We assessed how many academic dermatologists different residency programs produced. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273810 Tue, 16 Feb 2010 14:09:36 +0100 3273810 http://www.medworm.com/index.php?rid=3273809&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209007841%2Fabstract%3Frss%3Dyes To the Editor: Mineral make-up has become increasingly popular in recent years. While there is no legal definition, these products are typically loose powders. Marketed as containing mainly inert minerals, many claim to be “free of preservatives, talc, oil, fragrance, and other harmful chemicals” (http://bareescentuals.com/id/) or “specially formulated for sensitive skin” (http://www.physiciansformula.com/en-us/staticpage/mineralwear.html). In our contact dermatitis clinic, we have noted more patients using mineral make-up when they develop facial rashes. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273809 Tue, 16 Feb 2010 14:09:36 +0100 3273809 http://www.medworm.com/index.php?rid=3273808&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209007130%2Fabstract%3Frss%3Dyes To the Editor: Inpatient dermatology consultation remains an essential component of residency training; with the decline in direct admissions to dermatology services, dermatology inpatient care is provided more often in the consultative setting and can directly impact accurate diagnosis and management of patients. In 1994, Falanga et al reviewed 591 dermatology consults to a teaching hospital, concluding that common diseases may not be recognized or diagnosed correctly by non-dermatologists; misdiagnosis occurred in 78%, and two thirds resulted in treatment change. Nahass et al offered skin exams to medical inpatients; 35.9% of 231 had cutaneous findings, with one third of these directly related to systemic disease and/or reason for hospitalization. Recently Helms, Helms, and Brodell discu... Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273808 Tue, 16 Feb 2010 14:09:35 +0100 3273808 http://www.medworm.com/index.php?rid=3273807&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209007129%2Fabstract%3Frss%3Dyes To the Editor: Our preliminary results on the use of hypnosis in alopecia areata (AA), previously published in the JAAD, have suggested the possible efficacy of hypnosis in refractory AA forms. However, from the research finding of our latest study, another message emerges. In this prospective cohort study, a hypnotherapeutic approach was used without any other treatment, to compare the evolution of anxiety, depression, and health-related quality of life (HRQOL) of patients with AA that was refractory to conventional treatment, with control patients receiving only treatment for AA as usual. Only patients and controls presenting more than 30% hair loss with a minimal duration of 3 months were included. For ethical reasons, a nonrandomized controlled study protocol was selected. (Source: Jou... Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273807 Tue, 16 Feb 2010 14:09:35 +0100 3273807 http://www.medworm.com/index.php?rid=3273806&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209007075%2Fabstract%3Frss%3Dyes In this study they showed that 20 of 23 patients had greater than 80% clearance over the 3-week duration of Goeckerman therapy. Yet, it is interesting to note that only 3 of these subjects, “refractory to biologic therapy”, had previously received infliximab or adalimumab, agents expected to give greater than 80% clearance in the majority of patients. Thus this comparison and statement concerning “resistance to biologics” is certainly not warranted. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273806 Tue, 16 Feb 2010 14:09:35 +0100 3273806 http://www.medworm.com/index.php?rid=3273805&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS019096220900704X%2Fabstract%3Frss%3Dyes To the Editor: Few studies have compared diagnostic accuracy rates between teledermatologists (TDs) based on the gold standard of histopathology, and none have reported accuracy rates (histopathology as standard) between clinic dermatologists (CDs) viewing the same patients as TDs nor accuracy (histopathology as standard) of management plans. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273805 Tue, 16 Feb 2010 14:09:35 +0100 3273805 http://www.medworm.com/index.php?rid=3273804&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209006938%2Fabstract%3Frss%3Dyes To the Editor: Ultraviolet (UV) radiation causes sunburn, immunosuppression, pigmentary changes, photoaging, and skin cancer in a wavelength-dependent fashion. More than 95% of the incident UV radiation is ultraviolet A (UVA; 320-400 nm), which penetrates into the dermis. It induces DNA damage through the formation of reactive oxygen species (ROS), which are involved in oxidative base damage. ROS also induce matrix metalloproteinase (MMP) upregulation, which is partially responsible for skin photoaging. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273804 Tue, 16 Feb 2010 14:09:35 +0100 3273804 http://www.medworm.com/index.php?rid=3273803&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209006732%2Fabstract%3Frss%3Dyes We report the cases of two patients with DH who described significant flares after ingestion of cornstarch. Both followed a strict gluten-free diet with good symptom control, only requiring occasional dapsone after unavoidable gluten ingestion. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273803 Tue, 16 Feb 2010 14:09:35 +0100 3273803 http://www.medworm.com/index.php?rid=3273802&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209010950%2Fabstract%3Frss%3Dyes To the Editor: Wright et al documented nine cases of cutaneous leishmaniasis acquired in Texas between 2005 and 2007 and offered suggestions for the apparent movement of the disease into northeast Texas. Their statement, however, that all 30 previously reported cases were in south-central Texas is incorrect. McHugh et al documented one case in Brown County in Central Texas with a date of onset of June 1988 and another in the same county with a date of onset of 1992. One in Albany, Shackelford County, Texas—approximately 132 miles due west of the Dallas–Fort Worth metroplex—had a date of onset of November 1994 (this case was incorrectly reported in Fig 1 of Wright et al as occurring with the other two cases in Brown County, 70 miles to south). So there are some historic data indicatin... Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273802 Tue, 16 Feb 2010 14:09:35 +0100 3273802 http://www.medworm.com/index.php?rid=3273801&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209010597%2Fabstract%3Frss%3Dyes To the Editor: We note that Goeckerman treatment (ultraviolet light phototherapy plus crude coal tar) was considered as one of the top 10 options for managing moderate to severe psoriasis for only six (including three that concerned its use in pregnancy) of the 32 critically challenging case scenarios in the consensus statement recently published in the Journal. In contrast, at Mayo Clinic, Goeckerman treatment is one of our top considerations (and often the top choice) for managing the vast majority of scenarios described in this article. Goeckerman treatment has been well documented for decades to be extraordinarily effective, safe, and associated with long-lasting remission; it is also cost effective (current cost, approximately $10000-12000) and is associated with a low incidence of ad... Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273801 Tue, 16 Feb 2010 14:09:34 +0100 3273801 http://www.medworm.com/index.php?rid=3273800&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209009979%2Fabstract%3Frss%3Dyes To the Editor: I read with interest both the review and recent study by Gathers et al and would like to make a few comments as follows: The author's statements on the lack of epidemiologic data suggest that they may not be aware of two published population studies that examine these very questions. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273800 Tue, 16 Feb 2010 14:09:33 +0100 3273800 http://www.medworm.com/index.php?rid=3273797&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209005441%2Fabstract%3Frss%3Dyes We describe 4 patients with early-onset recurrent fevers, annular violaceous plaques, persistent violaceous eyelid swelling, low weight and height, lipodystrophy, hepatomegaly, and a range of visceral inflammatory manifestations. Laboratory abnormalities included chronic anemia, elevated acute-phase reactants, and raised liver enzymes. Histopathologic examination of lesional skin showed atypical mononuclear infiltrates of myeloid lineage and mature neutrophils. Our patients have a distinctive early-onset, chronic inflammatory condition with atypical or immature myeloid infiltrates in the skin. We propose the acronym CANDLE (chronic atypical neutrophilic dermatosis with lipodystrophy and elevated temperature) syndrome for this newly described disorder, which is probably genetic in origin. (... Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273797 Tue, 16 Feb 2010 14:09:31 +0100 3273797 http://www.medworm.com/index.php?rid=3273796&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209022117%2Fabstract%3Frss%3Dyes Dialogues in Dermatology, a monthly audio program from the American Academy of Dermatology, contains discussions between dermatologists on timely topics. Commentaries from Dialogues Editor-in-Chief Jacqueline M. Junkins-Hopkins, MD, are provided after each discussion as a topic summary and are provided here as a special service to readers of the Journal of the American Academy of Dermatology. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273796 Tue, 16 Feb 2010 14:09:31 +0100 3273796 http://www.medworm.com/index.php?rid=3273794&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209007737%2Fabstract%3Frss%3Dyes Conclusion: The dermal variant of BMT is a tumor of younger adults and children that can be associated with lymph node disease and a potential for morphologic and biologic progression when inadequately treated. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273794 Tue, 16 Feb 2010 14:09:30 +0100 3273794 http://www.medworm.com/index.php?rid=3273793&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209006963%2Fabstract%3Frss%3Dyes Conclusion: The data presented reinforce the differential diagnosis of tumors with an epidermotropic growth pattern and the importance of immunohistochemical staining in the histologic workup of such tumors: squamous cell carcinoma in situ, melanoma, mycosis fungoides, eccrine porocarcinoma, sebaceous carcinoma of the eyelid, mammary and extramammary Paget disease, MCC, and epidermotropic metastases. It is notable that 3 of 6 identified tumors were located on the eyelid; further study of epidermotropic MCC may shed more light on this finding, either as an unusual coincidence or a finding with unexplained significance. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273793 Tue, 16 Feb 2010 14:09:30 +0100 3273793 http://www.medworm.com/index.php?rid=3273792&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209009621%2Fabstract%3Frss%3Dyes Background: Injectable poly-L-lactic acid (PLLA) is a synthetic, biodegradable, biocompatible polymer device.Objective: We sought to compare the efficacy and safety of injectable PLLA with human-derived collagen in treating nasolabial fold wrinkles.Methods: In this randomized, evaluator-blinded, parallel-group, multicenter study, subjects received injectable PLLA (n = 116) or collagen (n = 117) injections (1-4 visits, 3-week intervals). Wrinkle Assessment Scale scores were calculated at screening; posttreatment week 3; months 3, 6, 9, and 13 (injectable PLLA or collagen groups); and months 19 and 25 (injectable PLLA group). Safety data were obtained from subject interviews and case report forms.Results: Injectable PLLA significantly improved mean Wrinkle Assessment Scale scores (all time p... Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273792 Tue, 16 Feb 2010 14:09:30 +0100 3273792 http://www.medworm.com/index.php?rid=3273790&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962210000952%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273790 Tue, 16 Feb 2010 14:09:29 +0100 3273790 http://www.medworm.com/index.php?rid=3273789&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209006860%2Fabstract%3Frss%3Dyes Conclusion: The safety profile of MEDI-545 supports further clinical development. IFN-α does not appear to be significantly involved in the maintenance of established plaque psoriasis. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273789 Tue, 16 Feb 2010 14:09:29 +0100 3273789 http://www.medworm.com/index.php?rid=3273787&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962210000940%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273787 Tue, 16 Feb 2010 14:09:29 +0100 3273787 http://www.medworm.com/index.php?rid=3273786&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209011451%2Fabstract%3Frss%3Dyes See related article on page 411 Onychomycosis is a common disorder and makes up approximately half of the nail disorders and 30% of the dermatophytoses we see as dermatologists. In older individuals the prevalence is high and likely approaches 60% or more in those older than 70 years. During the 1990s, onychomycosis was “hot,” not in any small part because of the onychomycosis treatment battles between orally administered terbinafine and itraconazole. Since 1996, however, no new Food and Drug Administration–approved systemic drugs for onychomycosis have come to market. During this time, the use of griseofulvin for tinea unguium has greatly diminished because of the greater efficacy of terbinafine and itraconazole. Topical ciclopirox lacquer is the latest onychomycosis drug to be app... Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273786 Tue, 16 Feb 2010 14:09:29 +0100 3273786 http://www.medworm.com/index.php?rid=3273785&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209011608%2Fabstract%3Frss%3Dyes Conclusion: The administration of systemic T to treat the first episode of onychomycosis may provide better long-term success than I in those patients with a complete response. Other factors including the presence of predisposing factors, use of nail lacquer as a prophylactic treatment, and the dermatophyte strain isolated were not significantly related to relapse. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273785 Tue, 16 Feb 2010 14:09:28 +0100 3273785 http://www.medworm.com/index.php?rid=3273784&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209009359%2Fabstract%3Frss%3Dyes See related article on page 402 Hair is a complex protein-based fiber of significant value for the perception of human beauty. All ancient civilizations and modern societies appreciate the appearance of “healthy” hair, yet defining the chemical structure that correlates with the image of hair health has proved challenging for the cosmetic chemist. Khumalo et al investigated the effect of hair straightening on hair chemistry as compared to virgin black tightly curled hair. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273784 Tue, 16 Feb 2010 14:09:28 +0100 3273784 http://www.medworm.com/index.php?rid=3273783&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209009360%2Fabstract%3Frss%3Dyes Conclusions: ‘Relaxers’ are associated with reduced cystine consistent with fragile damaged hair. A decrease in citrulline and glutamine has been associated with inflammation; prospective studies are needed to investigate whether or how ‘relaxers’ induce inflammation. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273783 Tue, 16 Feb 2010 14:09:28 +0100 3273783 http://www.medworm.com/index.php?rid=3273782&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962210000939%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273782 Tue, 16 Feb 2010 14:09:28 +0100 3273782 http://www.medworm.com/index.php?rid=3273778&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962210000927%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273778 Tue, 16 Feb 2010 14:09:28 +0100 3273778 http://www.medworm.com/index.php?rid=3273777&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209014984%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273777 Tue, 16 Feb 2010 14:09:28 +0100 3273777 http://www.medworm.com/index.php?rid=3273776&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209014972%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273776 Tue, 16 Feb 2010 14:09:28 +0100 3273776 http://www.medworm.com/index.php?rid=3273775&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209014480%2Fabstract%3Frss%3Dyes Treatments for localized adiposities range from topical creams to liposuction. Most treatments lack a substantial proof of efficacy. The unpredictable treatment outcome can be related to the fact that cellulite adipose tissue is physiologically and biochemically different from subcutaneous tissue found elsewhere in the body. Part II of this two-part series on cellulite reviews the various treatment options that are currently available for human adipose tissue including, but not limited to, cellulite. It also focuses on newer techniques that can be potentially useful in the future for the treatment of cellulite.Learning objectives: After completing this learning activity, participants should be able to understand the wide range of treatments available for localized adiposities including, bu... Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273775 Tue, 16 Feb 2010 14:09:28 +0100 3273775 http://www.medworm.com/index.php?rid=3273774&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962210000915%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273774 Tue, 16 Feb 2010 14:09:28 +0100 3273774 http://www.medworm.com/index.php?rid=3273773&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209015072%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273773 Tue, 16 Feb 2010 14:09:28 +0100 3273773 http://www.medworm.com/index.php?rid=3273772&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS019096220901500X%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273772 Tue, 16 Feb 2010 14:09:28 +0100 3273772 http://www.medworm.com/index.php?rid=3273771&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209014492%2Fabstract%3Frss%3Dyes Cellulite is a topographic skin change that is nearly ubiquitous in postpubertal women. Treatment remains elusive. The various treatments currently available are only partially or temporarily effective. Newer therapeutic modalities continue to evolve without much understanding of the complex nature of cellulite. The successful treatment of cellulite will ultimately depend upon our understanding of the pathophysiology of cellulite adipose tissue. Part I of this two-part series on cellulite reviews how the concept and perception of cellulite has evolved over time and its proposed etiologies. The article also focuses on the physiology of human adipose tissue, particularly regarding cellulite.Learning objectives: After completing this learning activity, participants should be able to different... Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273771 Tue, 16 Feb 2010 14:09:27 +0100 3273771 http://www.medworm.com/index.php?rid=3367392&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962208012000%2Fabstract%3Frss%3Dyes We present a case of osteonecrosis of the jaw resembling two flesh-colored papules associated with dental sinus tracts to highlight the clinical manifestations that dermatologists may encounter, and review the literature on this rare but morbid condition. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367392 Fri, 12 Feb 2010 00:00:00 +0100 3367392 http://www.medworm.com/index.php?rid=3367391&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209006872%2Fabstract%3Frss%3Dyes We report 3 cases of periorbital mucinosis occurring in association with other cutaneous signs of lupus erythematosus. Based on a review of the literature, periorbital mucinosis is a rare and not widely recognized clinical manifestation of the disease. Although unusual, familiarity with periorbital mucinosis as a manifestation of lupus erythematosus broadens our understanding of these entities and expands the spectrum of cutaneous lupus erythematosus. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367391 Fri, 12 Feb 2010 00:00:00 +0100 3367391 http://www.medworm.com/index.php?rid=3367395&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209003600%2Fabstract%3Frss%3Dyes This article aims to identify key drivers of consumer appeal by comparing tanning advertising strategies to those used by tobacco marketers. Tobacco advertising was selected as a reference framework because it is both well documented and designed to promote a product with known health hazards. Two thousand advertisements from 4 large tobacco advertisement databases were analyzed for type of advertisement strategy used, and 4 advertising method categories were devised to incorporate the maximum number of advertisements reviewed. Subsequently, contemporary tanning advertisements were collected from industry magazines and salon websites and evaluated relative to the identified strategy profiles. Both industries have relied on similar advertising strategies, including mitigating health concern... Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367395 Mon, 08 Feb 2010 00:00:00 +0100 3367395 http://www.medworm.com/index.php?rid=3367382&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209007099%2Fabstract%3Frss%3Dyes Conclusions: OFG can show multiple facial and mucosal clinical features. Long-term treatment with topical and/or combined therapy is needed in the majority of patients. Response to therapy is highly variable even though in the long-term complete/partial disease resolution can be obtained in the majority of patients. Mucosal ulceration tends to be more recalcitrant than orofacial swelling. Adverse side effects of therapy are rare. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367382 Fri, 05 Feb 2010 00:00:00 +0100 3367382 http://www.medworm.com/index.php?rid=3367377&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209008846%2Fabstract%3Frss%3Dyes Conclusions: Both imiquimod 2.5% and 3.75% creams were more effective than placebo and were well tolerated when administered daily as a 2-week on/off/on regimen to treat actinic keratoses. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367377 Thu, 04 Feb 2010 00:00:00 +0100 3367377 http://www.medworm.com/index.php?rid=3367375&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209006999%2Fabstract%3Frss%3Dyes Conclusions: Both imiquimod 2.5% and 3.75% creams were more effective than placebo and had an acceptable safety profile when administered daily as a 3-week on/off/on regimen. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367375 Thu, 04 Feb 2010 00:00:00 +0100 3367375 http://www.medworm.com/index.php?rid=3367396&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS019096220901250X%2Fabstract%3Frss%3Dyes Conclusions: Currently limited and inconclusive data are unable to detect an association between topical corticosteroids and congenital abnormality, preterm delivery, or stillbirth. The current evidence shows no statistically significant difference between pregnant women who use and those who do not use topical corticosteroids. However, there does appear to be an association of very potent topical corticosteroids with low birthweight. Further cohort studies with comprehensive outcome measures, consideration of corticosteroid potency, dosage and indications, and a large sample size are needed. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367396 Mon, 01 Feb 2010 00:00:00 +0100 3367396 http://www.medworm.com/index.php?rid=3367379&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209007087%2Fabstract%3Frss%3Dyes Conclusions are limited by the fact that this was a retrospective, uncontrolled study.Conclusions: Pigmented Bowen's disease has a characteristic dermatoscopic pattern. Linear arrangement of brown and/or gray dots and/or coiled vessels is a specific clue to pigmented Bowen's disease. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3367379 Mon, 18 Jan 2010 00:00:00 +0100 3367379 http://www.medworm.com/index.php?rid=3273795&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209005027%2Fabstract%3Frss%3Dyes X-linked ichthyosis (XLI) is an X-linked recessive disorder of cutaneous keratinization with possible extracutaneous manifestations. It was first described as a distinct type of ichthyosis in 1965. XLI is caused by a deficiency in steroid sulfatase activity, which results in abnormal desquamation and a retention hyperkeratosis. XLI is usually evident during the first few weeks of life as polygonal, loosely adherent translucent scales in a generalized distribution that desquamate widely. These are quickly replaced by large, dark brown, tightly adherent scales occurring primarily symmetrically on the extensor surfaces and the side of the trunk. In addition, extracutaneous manifestations such as corneal opacities, cryptorchidism, and abnormalities related to contiguous gene syndromes may be o... Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273795 Mon, 18 Jan 2010 00:00:00 +0100 3273795 http://www.medworm.com/index.php?rid=3273788&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209003569%2Fabstract%3Frss%3Dyes Conclusions: Folliculotropic MF is a rare but well-defined clinicopathological variant of MF. Although refractory to standard therapies used in classic MF, most of our patients showed only slow disease progression. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273788 Mon, 18 Jan 2010 00:00:00 +0100 3273788 http://www.medworm.com/index.php?rid=3173307&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209022531%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173307 Fri, 15 Jan 2010 14:02:09 +0100 3173307 http://www.medworm.com/index.php?rid=3173306&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS019096220902252X%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173306 Fri, 15 Jan 2010 14:02:09 +0100 3173306 http://www.medworm.com/index.php?rid=3173305&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209022506%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173305 Fri, 15 Jan 2010 14:02:09 +0100 3173305 http://www.medworm.com/index.php?rid=3173304&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209022518%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173304 Fri, 15 Jan 2010 14:02:09 +0100 3173304 http://www.medworm.com/index.php?rid=3173303&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209022543%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173303 Fri, 15 Jan 2010 14:02:09 +0100 3173303 http://www.medworm.com/index.php?rid=3173302&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962208011572%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173302 Fri, 15 Jan 2010 14:02:08 +0100 3173302 http://www.medworm.com/index.php?rid=3173301&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962208011419%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173301 Fri, 15 Jan 2010 14:02:08 +0100 3173301 http://www.medworm.com/index.php?rid=3173300&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209009529%2Fabstract%3Frss%3Dyes A 52-year-old white male presented with worsening blistering skin lesions over the past 2 weeks and reported a history of similar symptoms since shortly after birth. The physical examination was notable for vesicles, bullae, scarring, and mutilation of the face, hands, and forearms, while the upper arms, trunk, and lower extremities appeared normal ( and ). Laboratory values were remarkable for low hemoglobin and iron, and markedly elevated urine porphyrins. The patient mentioned that a distant family member has a similar skin condition. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173300 Fri, 15 Jan 2010 14:02:08 +0100 3173300 http://www.medworm.com/index.php?rid=3173299&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209001467%2Fabstract%3Frss%3Dyes We report a case of 7-year-old white female who presented to our clinic with a 3-year history of three 3- to 4-mm, skin-colored papules on her nose and one on each foot (). The papules were asymptomatic and there was no history of trauma. A biopsy of the lesion on the right foot revealed a well circumscribed proliferation of cells with delicate spindled nuclei in a loose myxoid stroma in the superficial dermis, findings that are characteristic of PEN (). (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173299 Fri, 15 Jan 2010 14:02:08 +0100 3173299 http://www.medworm.com/index.php?rid=3173297&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209001418%2Fabstract%3Frss%3Dyes We report an exceptional case of pigmented BD of the palm clinically suspicious for melanoma, whose correct diagnosis was suggested by dermoscopy. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173297 Fri, 15 Jan 2010 14:02:08 +0100 3173297 http://www.medworm.com/index.php?rid=3173296&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209001406%2Fabstract%3Frss%3Dyes We report a case of LyP with an unusual localized presentation. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173296 Fri, 15 Jan 2010 14:02:07 +0100 3173296 http://www.medworm.com/index.php?rid=3173295&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209006896%2Fabstract%3Frss%3Dyes To the Editor: Key surgical principles include minimizing dead space, encouraging wound eversion, minimizing tension across the epidermal component of the wound, restricting absorbable suture material to the reticular dermis, and maintaining adequate vascular supply to the healing wound. Twenty years ago, Zitelli and Moy described the buried vertical mattress suture. Several other modifications of absorbable dermal suturing techniques have been proposed, including the modified buried vertical mattress technique of Sadick et al, the percutaneous buried vertical mattress suture, and the fully buried horizontal mattress suture described by Alam and Goldberg. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173295 Fri, 15 Jan 2010 14:02:07 +0100 3173295 http://www.medworm.com/index.php?rid=3173294&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209006598%2Fabstract%3Frss%3Dyes To the Editor: The association of pemphigus with autoimmune thyroid diseases, namely Hashimoto thyroiditis and Graves disease, is well known. Nevertheless, controlled studies evaluating thyroidal autoimmunity in pemphigus patients are limited in the English-language literature. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173294 Fri, 15 Jan 2010 14:02:06 +0100 3173294 http://www.medworm.com/index.php?rid=3173293&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209006586%2Fabstract%3Frss%3Dyes To the Editor: On August 27, 2007, the US Food and Drug Administration (FDA) released a proposed amendment to the 1999 sunscreen monograph. An important aspect of this amendment is that the FDA has proposed that manufacturers label their products with a specific sun protection factor (SPF) value up to 50; sunscreens with SPFs >50 would be labeled as 50+. We conducted a double-blind, randomized, split-face clinical study to evaluate whether a statistically significant difference exists between the sunburn protective effects of a SPF 50 sunscreen versus a SPF 85 formulation. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173293 Fri, 15 Jan 2010 14:02:06 +0100 3173293 http://www.medworm.com/index.php?rid=3173292&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209010998%2Fabstract%3Frss%3Dyes To the Editor: I read with great interest the article comparing various treatment modalities for nonmelanoma skin cancer in the July 2009 issue of the Journal. As a critical reader, I typically pay attention to the “financial disclosure” section listed for each article. In this article, no financial conflicts were declared. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173292 Fri, 15 Jan 2010 14:02:06 +0100 3173292 http://www.medworm.com/index.php?rid=3173291&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209000085%2Fabstract%3Frss%3Dyes To the Editor: The use of botulinum neurotoxin A is the most frequent intervention in aesthetic medicine. Sales of the two main preparations—Botox (Allergan Inc, Irvine, CA) and Dysport (Ipsen Ltd, Slough, Berkshire, UK)—amounted to USD $1 billion in 2007, and the trend is still growing. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173291 Fri, 15 Jan 2010 14:02:06 +0100 3173291 http://www.medworm.com/index.php?rid=3173290&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209005088%2Fabstract%3Frss%3Dyes We present immunohistochemical evidence to show that the proliferating fibrocytes of NSF express phospho-70-s6 kinase (PI-3-K), a protein downstream of PI-3-K, and the target of the drug rapamycin. In our patient, use of rapamycin resulted in rapid clinical improvement marked by reduced edema, reduced skin induration, and decreased pain. This suggests a possible role for PI-3-K and rapamycin (mTOR) pathways in the pathogenesis of NSF. Drugs that inhibit these pathways may be a target for future therapy. While our patient did attribute disease onset to GdCA exposure, used on a single occasion for abdominal imaging, he was also exposed to iron, calcium, and darbepoetin alpha at the time of imaging. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173290 Fri, 15 Jan 2010 14:02:06 +0100 3173290 http://www.medworm.com/index.php?rid=3173287&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209003922%2Fabstract%3Frss%3Dyes We report a case of a young patient with SAPHO syndrome who later presented with extensive iliofemoral deep vein thromboses and seven pulmonary emboli. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173287 Fri, 15 Jan 2010 14:02:05 +0100 3173287 http://www.medworm.com/index.php?rid=3173285&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS019096220800916X%2Fabstract%3Frss%3Dyes The pigment synthesizing melanoma, so-called animal type melanoma, is a rare variant of melanoma that is characterized by prominent melanin production and an unpredictable prognosis. Congenital onset of this melanoma is exceedingly rare. A 2-month-old Korean girl had a black nodule and a satellite black macule on the scalp which were noticed at birth. She received a surgical resection 3 months later because of rapidly growing lesions and the histopathologic features of a pigment synthesizing melanoma. Two months later, she returned with cervical area swelling, and the excised multiple lymph nodes showed metastatic malignant melanoma. The exact origin and pathogenesis of congenital pigment synthesizing melanoma is different from the more common forms of melanoma and remains poorly understoo... Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173285 Fri, 15 Jan 2010 14:02:04 +0100 3173285 http://www.medworm.com/index.php?rid=3173283&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209022750%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173283 Fri, 15 Jan 2010 14:02:03 +0100 3173283 http://www.medworm.com/index.php?rid=3173282&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209022105%2Fabstract%3Frss%3Dyes Warshaw EM, Lederle FA, Grill JP, Gravely AA, Bangerter AK, Fortier LA, et al. Accuracy of teledermatology for pigmented neoplasms. J Am Acad Dermatol 2009;61:753-65. In the article above, the final row of Table V printed incorrectly. The corrected table appears below. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173282 Fri, 15 Jan 2010 14:02:03 +0100 3173282 http://www.medworm.com/index.php?rid=3173278&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209022749%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173278 Fri, 15 Jan 2010 14:02:02 +0100 3173278 http://www.medworm.com/index.php?rid=3173276&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209009888%2Fabstract%3Frss%3Dyes Conclusion: This study suggests that, similarly to vulvar carcinoma, penile SCC occurs in association with two types of penile lesions: undifferentiated (or bowenoid) PIN and LS-linked differentiated PIN and/or SH. It appears that the subtype of these carcinomas is related to these adjacent lesions. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173276 Fri, 15 Jan 2010 14:02:02 +0100 3173276 http://www.medworm.com/index.php?rid=3173275&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209009645%2Fabstract%3Frss%3Dyes Conclusion: Our data demonstrate that trichoadenoma typically retains cytokeratin 20–positive Merkel cells but lacks Ber-EP4 and androgen receptor expression. Trichoadenoma is a distinct follicular tumor related but not identical to desmoplastic trichoepithelioma. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173275 Fri, 15 Jan 2010 14:02:02 +0100 3173275 http://www.medworm.com/index.php?rid=3173274&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209009396%2Fabstract%3Frss%3Dyes Conclusion: The absence of nerve tissue in a Mohs surgery specimen, coupled with signs of cranial nerve involvement, could be important early indicators of PNI progressing to LMC. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173274 Fri, 15 Jan 2010 14:02:01 +0100 3173274 http://www.medworm.com/index.php?rid=3173273&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209007245%2Fabstract%3Frss%3Dyes Conclusion: Ultrasound appears to be a safe and effective modality for facial skin tightening. A single ultrasound treatment of the forehead produced on average brow height elevation of slightly less than 2 mm. Most treated individuals responded, commonly with accompanying transitory mild erythema and edema. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173273 Fri, 15 Jan 2010 14:02:01 +0100 3173273 http://www.medworm.com/index.php?rid=3173265&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209007828%2Fabstract%3Frss%3Dyes Conclusions: This clinical study represents the first formal assessment of IFX for treatment of moderate to severe HS. IFX was well tolerated, no unexpected safety issues were identified, and improvements in pain intensity, disease severity, and quality of life were demonstrated with concomitant reduction in clinical markers of inflammation. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173265 Fri, 15 Jan 2010 14:02:00 +0100 3173265 http://www.medworm.com/index.php?rid=3173264&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209022737%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173264 Fri, 15 Jan 2010 14:02:00 +0100 3173264 http://www.medworm.com/index.php?rid=3173263&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209013784%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173263 Fri, 15 Jan 2010 14:02:00 +0100 3173263 http://www.medworm.com/index.php?rid=3173262&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209013772%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173262 Fri, 15 Jan 2010 14:01:59 +0100 3173262 http://www.medworm.com/index.php?rid=3173261&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209013620%2Fabstract%3Frss%3Dyes Various therapeutic agents have been described for the treatment of alopecia areata (AA), but none are curative or preventive. The aim of AA treatment is to suppress the activity of the disease. The high rate of spontaneous remission and the paucity of randomized, double-blind, placebo-controlled studies make the evidence-based assessment of these therapies difficult. The second part of this two-part series on AA discusses treatment options in detail and suggests treatment plans according to specific disease presentation. It also reviews recently reported experimental treatment options and potential directions for future disease management.Learning objectives: After completing this learning activity, participants should be able to compare the efficacy and safety of various treatment option... Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173261 Fri, 15 Jan 2010 14:01:59 +0100 3173261 http://www.medworm.com/index.php?rid=3173260&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209022725%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173260 Fri, 15 Jan 2010 14:01:59 +0100 3173260 http://www.medworm.com/index.php?rid=3173259&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209013760%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173259 Fri, 15 Jan 2010 14:01:59 +0100 3173259 http://www.medworm.com/index.php?rid=3173258&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209013759%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173258 Fri, 15 Jan 2010 14:01:59 +0100 3173258 http://www.medworm.com/index.php?rid=3173257&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209013632%2Fabstract%3Frss%3Dyes Alopecia areata (AA) is an autoimmune disease that presents as nonscarring hair loss, although the exact pathogenesis of the disease remains to be clarified. Disease prevalence rates from 0.1% to 0.2% have been estimated for the United States. AA can affect any hair-bearing area. It often presents as well demarcated patches of nonscarring alopecia on skin of overtly normal appearance. Recently, newer clinical variants have been described. The presence of AA is associated with a higher frequency of other autoimmune diseases. Controversially, there may also be increased psychiatric morbidity in patients with AA. Although some AA features are known poor prognostic signs, the course of the disease is unpredictable and the response to treatment can be variable. Part one of this two-part series ... Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3173257 Fri, 15 Jan 2010 14:01:59 +0100 3173257 http://www.medworm.com/index.php?rid=3273791&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209007105%2Fabstract%3Frss%3Dyes Conclusion: We identified for the first time to our knowledge autoantibodies to meibomian glands and tarsal muscle in El Bagre-EPF. Our findings suggest that the autoantibodies to the ocular structures cause the clinical and histopathological findings in the ocular lesions in El Bagre-EPF. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273791 Mon, 11 Jan 2010 00:00:00 +0100 3273791 http://www.medworm.com/index.php?rid=3273781&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209013565%2Fabstract%3Frss%3Dyes See related articles on pages 387 and 393 For both patients and clinicians, lichen planopilaris (LPP) is a very challenging disease. Clinically and histologically, we observe active inflammation and disease progression, but our safe and simple anti-inflammatory medications often prove to be woefully inadequate. After topical and intralesional corticosteroids have been tried without good disease control, what are we to do? (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273781 Mon, 11 Jan 2010 00:00:00 +0100 3273781 http://www.medworm.com/index.php?rid=3273780&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209006057%2Fabstract%3Frss%3Dyes Background: Lichen planopilaris (LPP) is a chronic inflammatory disorder that causes permanent scalp hair loss and significant patient discomfort.Objectives: We sought to determine the efficacy and safety of mycophenolate mofetil (MMF) for treatment of LPP in patients who had failed prior topical, intralesional, or oral anti-inflammatory medications such as hydroxychloroquine or cyclosporine.Methods: We conducted a retrospective chart review of 16 adult patients with LPP treated with at least 6 months of MMF in an open-label, single-center study from 2003 to 2007. Subjective and objective end points were quantified using the LPP Activity Index (LPPAI) and scores before and after treatment were assessed using a paired t test. Adverse events were monitored.Results: Patients who completed tre... Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273780 Mon, 11 Jan 2010 00:00:00 +0100 3273780 http://www.medworm.com/index.php?rid=3273779&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209012110%2Fabstract%3Frss%3Dyes Conclusions: Hydroxychloroquine is effective in decreasing symptoms and signs in LPP and FFA as shown by significant reduction in the LPPAI in 69% and 83% of patients after 6 and 12 months of treatment, respectively. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3273779 Mon, 11 Jan 2010 00:00:00 +0100 3273779 http://www.medworm.com/index.php?rid=3093892&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209014650%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3093892 Thu, 17 Dec 2009 14:02:51 +0100 3093892 http://www.medworm.com/index.php?rid=3093891&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209014649%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3093891 Thu, 17 Dec 2009 14:02:51 +0100 3093891 http://www.medworm.com/index.php?rid=3093890&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209014637%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3093890 Thu, 17 Dec 2009 14:02:51 +0100 3093890 http://www.medworm.com/index.php?rid=3093889&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209014704%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3093889 Thu, 17 Dec 2009 14:02:51 +0100 3093889 http://www.medworm.com/index.php?rid=3093888&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209014686%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3093888 Thu, 17 Dec 2009 14:02:51 +0100 3093888 http://www.medworm.com/index.php?rid=3093887&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209014625%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3093887 Thu, 17 Dec 2009 14:02:51 +0100 3093887 http://www.medworm.com/index.php?rid=3093886&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209014613%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3093886 Thu, 17 Dec 2009 14:02:51 +0100 3093886 http://www.medworm.com/index.php?rid=3093885&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209014601%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3093885 Thu, 17 Dec 2009 14:02:51 +0100 3093885 http://www.medworm.com/index.php?rid=3093884&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209014583%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3093884 Thu, 17 Dec 2009 14:02:51 +0100 3093884 http://www.medworm.com/index.php?rid=3093883&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209014595%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3093883 Thu, 17 Dec 2009 14:02:51 +0100 3093883 http://www.medworm.com/index.php?rid=3093882&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962208010207%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3093882 Thu, 17 Dec 2009 14:02:51 +0100 3093882 http://www.medworm.com/index.php?rid=3093881&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962208011407%2Fabstract%3Frss%3Dyes (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3093881 Thu, 17 Dec 2009 14:02:51 +0100 3093881 http://www.medworm.com/index.php?rid=3093880&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209005283%2Fabstract%3Frss%3Dyes The dermatologic community lost a true master on April 22, 2008, when Edward A. Krull died at 78 years of age (). His contributions to dermatology are legendary: a pioneer in dermatologic surgery who placed this subspecialty as an integral part of dermatology, a renowned international lecturer, a teacher par excellence, and a superb mentor. He was a respected colleague and a beloved friend to many. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3093880 Thu, 17 Dec 2009 14:02:51 +0100 3093880 http://www.medworm.com/index.php?rid=3093879&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962208024717%2Fabstract%3Frss%3Dyes I have had the privilege of being one of the people who has learned something about medicine and dermatology from Dr Ralph Grover. Ralph passed way on May 25, 2008. He was a physician, a teacher, a researcher, a friend, a father, and a husband. His home office in Floral Park, NY was a place where residents, medical students, and interns in training would rotate to learn from a dedicated teacher, where he stored all the information needed the old-fashioned way, on little 4 × 6 cards filled with beautiful drawings, diagramming where and what lesions looked like. Going to his office was as much like going to a relative's home as a doctor's office. Everyone knew about the pet ducks that he kept in his yard. And he spent time with his patients–as much as they needed. His wife, Jean, was alwa... Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3093879 Thu, 17 Dec 2009 14:02:48 +0100 3093879 http://www.medworm.com/index.php?rid=3093878&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209008895%2Fabstract%3Frss%3Dyes An 85-year-old man was referred to our department for a nonhealing lesion of approximately 3 months' duration on the right side of his lower back (). Agminated papules were also noted in the genitocrural region (). (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3093878 Thu, 17 Dec 2009 14:02:48 +0100 3093878 http://www.medworm.com/index.php?rid=3093877&cid=s_37696_12_f&fid=37696&url=http%3A%2F%2Fwww.eblue.org%2Farticle%2FPIIS0190962209002345%2Fabstract%3Frss%3Dyes A 70-year-old male presented with a 5-year history of pruritic plaques arising on his neck, the upper portion of his chest, and back. These lesions had slowly increased in size and were unresponsive to topical corticosteroids. His medical history was significant for mucinous cystadenocarcinoma of the pancreas that was successfully resected several years earlier; the patient deferred chemotherapy and radiation therapy. He denied recent fevers, night sweats, or unintentional weight loss. The physical examination revealed violaceous, indurated plaques with excoriations on his neck, the upper portion of his chest, and back ( and ). He had no regional lymphadenopathy or hepatosplenomegaly. (Source: Journal of the American Academy of Dermatology) Journal of the American Academy of Dermatology journals http://www.medworm.com/rss/comments.php?id=3093877 Thu, 17 Dec 2009 14:02:48 +0100 3093877