MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Journal of the European Academy of Dermatology and Venereology' source. Wed, 08 Feb 2012 13:12:34 +0100 http://www.medworm.com/index.php?rid=5667283&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2012.04450.x Conclusion  Systemic treatments for psoriasis resulted in heterogeneous effects on the parameters analysed. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5667283 Tue, 07 Feb 2012 05:00:00 +0100 5667283 http://www.medworm.com/index.php?rid=5667284&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2012.04459.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5667284 Mon, 06 Feb 2012 05:00:00 +0100 5667284 http://www.medworm.com/index.php?rid=5659873&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2012.04449.x AbstractThe skin‐blanching assay is used for the determination and bioequivalence of dermatologic glucocorticoids (GCs). The exact mechanism of the production of blanching is not fully understood, but it is considered that local vasoconstriction of the skin microvasculature and the consequent blood‐flow reduction cause this phenomenon. Several factors influence skin blanching, including drug concentration, duration of application, nature of vehicle, occlusion, posture and location. The intensity of vasoconstriction can be measured in several ways: visual or quantitative methods, such as reflectance spectroscopy, thermography, laser Doppler velocimetry and chromametry. In literature, contradicting results in the correlation of the skin‐blanching assay with different tests to determine... Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5659873 Sat, 04 Feb 2012 05:00:00 +0100 5659873 http://www.medworm.com/index.php?rid=5667282&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2012.04453.x Conclusion  Mutations and LOH in PTCH1 were also highly prevalent in Chinese sporadic BCCs. However, UV light plays a less role in causing these mutations, suggesting other potential mechanisms in the development of sporadic BCC in Chinese patients. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5667282 Wed, 01 Feb 2012 05:00:00 +0100 5667282 http://www.medworm.com/index.php?rid=5659872&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2012.04454.x Conclusion  The survival after recurrence of melanoma patients that has relapsed with only locoregional cutaneous metastasis depends on the mitotic rate of the primary tumor and the subcutaneous involvement of the metastasis. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5659872 Wed, 01 Feb 2012 05:00:00 +0100 5659872 http://www.medworm.com/index.php?rid=5638583&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04426.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5638583 Sun, 29 Jan 2012 17:57:39 +0100 5638583 http://www.medworm.com/index.php?rid=5638582&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04425.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5638582 Sun, 29 Jan 2012 17:57:37 +0100 5638582 http://www.medworm.com/index.php?rid=5638581&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04424.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5638581 Sun, 29 Jan 2012 17:57:35 +0100 5638581 http://www.medworm.com/index.php?rid=5597903&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04441.x Conclusion  Serum 8‐OHdG levels could be used as good biomarker for the early diagnosis of psoriasis and its management. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5597903 Sat, 14 Jan 2012 05:00:00 +0100 5597903 http://www.medworm.com/index.php?rid=5597902&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04442.x Conclusions  FMF with ELE as the first disease manifestation form an uncommon subgroup, clinically and genetically diverging from the rest of the FMF‐ELE patients. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5597902 Sat, 14 Jan 2012 05:00:00 +0100 5597902 http://www.medworm.com/index.php?rid=5581959&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04445.x Conclusion  Over the last decade, the number of patients hospitalized in Dermatological Departments has declined; moreover, patients hospitalized with dermatological disorders have been increasingly admitted to wards with a non‐dermatologist attending physician. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5581959 Fri, 13 Jan 2012 05:00:00 +0100 5581959 http://www.medworm.com/index.php?rid=5581958&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04446.x Conclusions  Our DE unit satisfies a genuine need. Its activity increased over 10 years, most likely because of the decrease in the number of dermatologists in France. Although our results are close to those reported in the literature, comparison with previously published studies is difficult because of the heterogeneity of the definition of DE. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5581958 Fri, 13 Jan 2012 05:00:00 +0100 5581958 http://www.medworm.com/index.php?rid=5581957&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04447.x Conclusion  Self‐assessment of erythema from diaries is unreliable. Erythema is considerably underestimated and possibly neglected. Even for the trained eye, it can be difficult to detect erythema. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5581957 Fri, 13 Jan 2012 05:00:00 +0100 5581957 http://www.medworm.com/index.php?rid=5581963&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04431.x Conclusion  Our data do not support prevalence of GST isoenzymes or polymorphisms as a protective effect against PLE. Especially a higher carrier frequency of GSTP1 Val105 as a protective factor against PLE which has been published before could not be proved. The GST genotypes GSTM1, GSTT1 and GSTP1 (including SNPs) seem to have no relevant association with PLE. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5581963 Mon, 09 Jan 2012 05:00:00 +0100 5581963 http://www.medworm.com/index.php?rid=5581962&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04433.x Conclusion  The present study confirms that topical nitrogen mustard is a safe and effective therapy. The treatment response in patients with parapsoriasis was not statistically different from the response in patients with MF. This supports, that parapsoriasis is not a distinct entity, but an early stage of MF. Nitrogen mustard should therefore still be considered as an important treatment modality in patients with early stages (parapsoriasis) and later stages of MF either as monotherapy or in combination with other topical or systemic therapies. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5581962 Mon, 09 Jan 2012 05:00:00 +0100 5581962 http://www.medworm.com/index.php?rid=5581961&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04437.x Conclusion  Dyslipoproteinemia is a common feature in patients with DM that is characterized by an increase in TG and a decrease in HDL‐C, suggesting a high risk of atherosclerosis. Inflammation might partly account for the changes of serum lipid profiles in DM. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5581961 Mon, 09 Jan 2012 05:00:00 +0100 5581961 http://www.medworm.com/index.php?rid=5581960&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04439.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5581960 Mon, 09 Jan 2012 05:00:00 +0100 5581960 http://www.medworm.com/index.php?rid=5572253&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04420.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5572253 Fri, 06 Jan 2012 05:00:00 +0100 5572253 http://www.medworm.com/index.php?rid=5560251&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04414.x Conclusions  Resveratrate exerts protective effects against repetitive ssUVR‐induced sunburn and suntan. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5560251 Thu, 05 Jan 2012 05:00:00 +0100 5560251 http://www.medworm.com/index.php?rid=5560250&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04428.x Conclusions  Serum testing of anti‐Dsg1 and anti‐Dsg3 in PV patients not only provides significant correlations with IIF, treatment and disease type, but may serve as a monitoring tool for clinical course and treatment guidance. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5560250 Thu, 05 Jan 2012 05:00:00 +0100 5560250 http://www.medworm.com/index.php?rid=5560249&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04432.x AbstractField cancerization is a term that describes the presence of genetic abnormalities in a tissue chronically exposed to a carcinogen. These abnormalities are responsible for the presence of multilocular clinical and sub‐clinical cancerous lesions that explains the increased risks of multiple cancers in this area. With respect to the skin, this term is used to define the presence of multiple non‐melanoma skin cancer, its precursors, actinic keratoses and dysplastic keratinocytes in sun exposed areas. The multiplicity of the lesions and the extent of the area influence the treatment decision. Providing at least equivalent efficacy and tolerability, field directed therapies are therefore often more worthwhile than lesion targeted approaches. Photodynamic therapy (PDT) with its selec... Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5560249 Thu, 05 Jan 2012 05:00:00 +0100 5560249 http://www.medworm.com/index.php?rid=5560248&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04435.x Conclusions  Our study increases the total number of FLG mutations. We clearly demonstrated that FLG loss‐of‐function mutations were significantly associated with AD in northern China. The FLG null mutations in the Chinese population differed not only from that in the European population but also from that in sub‐populations of Asians outside of the Chinese mainland. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5560248 Thu, 05 Jan 2012 05:00:00 +0100 5560248 http://www.medworm.com/index.php?rid=5560247&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04436.x Conclusion  Cathepsin K expression may contribute to tumour invasion and peculiar histopathological features, such as fibromucinous stroma around the tumour nests by mediating extracellular matrix degradation in BCC. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5560247 Thu, 05 Jan 2012 05:00:00 +0100 5560247 http://www.medworm.com/index.php?rid=5560259&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04406.x AbstractIn the past 5 years since their US introduction, there has been a rapid proliferation of light‐based hair removal devices intended for home‐use. In the last 2 years in Europe, sales already run into many tens of thousands of units with well‐known multi‐national companies entering the market. These guidelines provide a definition of light‐based home‐use technology, to inform healthcare professionals about home‐use light‐based technology and encourage manufacturers wishing to sell in Europe to adopt ‘best practice’. The review presents the current status on standards and regulation issues and considers home‐use safety issues, encompassing human, device and electrical safety, given risks to the eyes and skin from optical radiation both to the consumer and per... Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5560259 Tue, 03 Jan 2012 05:00:00 +0100 5560259 http://www.medworm.com/index.php?rid=5560258&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04407.x Conclusions  The total burden of BCC is underestimated by the absence of data on the occurrence of non‐histologically diagnosed BCCs in daily dermatological practice. It is pivotal for Dutch healthcare policy makers to acknowledge this to make accurate BCC‐related cost estimates. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5560258 Tue, 03 Jan 2012 05:00:00 +0100 5560258 http://www.medworm.com/index.php?rid=5560257&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04418.x Conclusion  Drug patch testing is a safe and useful method for the identification of CBZ as the culprit drug of SJS/TEN as well as DRESS. Testing of chemically or pharmacologically related AEDs may provide information on cross‐reactivity for these patients. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5560257 Tue, 03 Jan 2012 05:00:00 +0100 5560257 http://www.medworm.com/index.php?rid=5560256&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04421.x Conclusion  This original survey emphasizes the interest of greater multidisciplinary collaboration and the necessity to harmonize practice. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5560256 Tue, 03 Jan 2012 05:00:00 +0100 5560256 http://www.medworm.com/index.php?rid=5560255&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04423.x Conclusion  The use of confocal microscopy is likely to facilitate earlier diagnosis of Paget’s disease and the instigation of appropriate management with concomitant improvement in clinical outcomes. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5560255 Tue, 03 Jan 2012 05:00:00 +0100 5560255 http://www.medworm.com/index.php?rid=5560254&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04429.x Conclusions  A wide range of mucocutaneous disorders were observed in HIV‐infected Chinese patients. Oral candidiasis, P. marneffei infection and PPE may be the signs of advanced HIV infection. HAART had an impact on the spectrum of HIV‐associated mucocutaneous disorders. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5560254 Tue, 03 Jan 2012 05:00:00 +0100 5560254 http://www.medworm.com/index.php?rid=5560253&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04430.x Conclusion  This population was characterized by: a high prevalence in adult females, intermediate skin phototypes, disease precipitation by hormonal stimulus and familiar genetic influence. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5560253 Tue, 03 Jan 2012 05:00:00 +0100 5560253 http://www.medworm.com/index.php?rid=5560252&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04416.x AbstractBacterial skin and soft tissues infections (SSTI) often determine acute disease and frequent emergency recovering, and they are one of the most common causes of infection among groups of different ages. Given the variable presentation of SSTI, a thorough assessment of their incidence and prevalence is difficult. The presence of patient‐related (local or systemic) or environmental risk factors, along with the emergence of multi‐drug resistant pathogens, can promote SSTI. These infections may present with a wide spectrum of clinical features and different severity, and can be classified according to various criteria. Many bacterial species can cause SSTI, but Gram‐positive bacteria are the most frequently isolated, with a predominance of Staphylococcus aureus and Streptococcus ... Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5560252 Tue, 03 Jan 2012 05:00:00 +0100 5560252 http://www.medworm.com/index.php?rid=5560261&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04417.x Conclusion  Our study points to the possible role played by OPN in the pathogenesis of psoriasis and in reflecting disease severity. These standard therapeutic modalities used in the current study were associated with a significant decrease in PASI and OPN levels. They constitute highly effective therapeutic modalities for psoriasis, which might exert their anti‐psoriatic activity partially through altering the expression of OPN. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5560261 Mon, 02 Jan 2012 05:00:00 +0100 5560261 http://www.medworm.com/index.php?rid=5560260&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04419.x Conclusion  Cutaneous oxidative stress in patients with plantar warts may play a role in pathogenesis of the disease. The addition of topical drugs with antioxidative effects may be valuable in the treatment of warts. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5560260 Mon, 02 Jan 2012 05:00:00 +0100 5560260 http://www.medworm.com/index.php?rid=5608960&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04443.x Conclusion  Exposure to chronic mild stress in NC/Nga atopic‐like mice may result in altered expression patterns of substance P in the skin and hippocampus. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5608960 Sun, 01 Jan 2012 05:00:00 +0100 5608960 http://www.medworm.com/index.php?rid=5597901&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04444.x AbstractTwins have always fascinated medical research even before the discovery of DNA and the understanding of the differences between identical and non‐identical twins. Dermatology with the benefit of being able to visualize phenotypes was one of the first specialities reporting on the fascinating concordance in identical (MZ) twins in the 1920’s. Over the last 20 years, the heritability of skin diseases using twins has been clearly demonstrated, across a wide variety of traits including melanoma, polymorphic light eruption, psoriasis, eczema and acne. Other rarer diseases have also been shown to have a significant genetic basis such as lupus, sarcoidosis and lichen sclerosus. Following evidence of heritability for many skin disease the next step was Genome‐Wide Association Studi... Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5597901 Sun, 01 Jan 2012 05:00:00 +0100 5597901 http://www.medworm.com/index.php?rid=5581956&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04397.x Conclusions  Systemic isotretinoin and antibiotic treatments in acne patients precisely caused variations in the microbial floras of several sites of the body, while isotretinoin was commonly more responsible than antibiotics. Knowing that alterations in the microbial colonization of the flora regions may preceede infectious disease and bacterial resistance, treatment options and follow‐up procedures in acne vulgaris should be carefully determined to reduce the risk of destruction of the microbial flora. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5581956 Sun, 01 Jan 2012 05:00:00 +0100 5581956 http://www.medworm.com/index.php?rid=5572252&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04440.x Conclusions  Treatment preferences may change over time course and with treatment experience. Participants on injectables attach great importance to efficiency and convenience of therapies, and are highly satisfied with their treatment. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5572252 Sun, 01 Jan 2012 05:00:00 +0100 5572252 http://www.medworm.com/index.php?rid=5560246&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04438.x Conclusion  Digital dermatoscopic follow‐up facilitates the recognition of thin malignant melanomas and helps to reduce the number of unnecessary excisions. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5560246 Sun, 01 Jan 2012 05:00:00 +0100 5560246 http://www.medworm.com/index.php?rid=5552411&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04427.x AbstractAs the most common form of skin cancer, basal cell carcinoma (BCC) is typified by locally infiltrative growth and a very low risk of metastasis. On occasion, however, this otherwise indolent neoplasm may behave aggressively, demonstrating deep tissue invasion and a high rate of postsurgical recurrence. The pathogenesis and determinants of such tenacious growth are not completely understood. Only 1% of all BCC’s achieve the status of ‘giant’, as defined in 1988 by the American Joint Committee on Cancer. In this article, the authors provide a comprehensive review of the scientific literature on giant basal cell carcinoma (GBCC) of the skin and report their experience with this rare tumour subtype. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5552411 Sat, 31 Dec 2011 06:08:29 +0100 5552411 http://www.medworm.com/index.php?rid=5544660&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04415.x AbstractIn wound healing, a variety of mediators have been identified throughout the years. The mediators discussed here comprise growth factors, cytokines and chemokines. These mediators act via multiple (specific) receptors to facilitate wound closure. As research in the last years has led to many new findings, there is a need to give an overview on what is known, and on what might possibly play a role as a molecular target for future wound therapy. This review aims to keep the reader up to date with selected important and novel findings regarding growth factors, cytokines and chemokines in wound healing. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5544660 Wed, 28 Dec 2011 09:14:11 +0100 5544660 http://www.medworm.com/index.php?rid=5552413&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04422.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5552413 Wed, 28 Dec 2011 05:00:00 +0100 5552413 http://www.medworm.com/index.php?rid=5544661&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04413.x Conclusion  Decreased RBP4 levels are associated with the prevalence of Raynaud’s phenomenon in dcSSc and lcSSc, with the severity of interstitial lung disease in dcSSc, and with the degree of pulmonary vascular involvement in lcSSc, suggesting the possible contribution of RBP4 to the pathological events in this disorder. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5544661 Mon, 26 Dec 2011 05:00:00 +0100 5544661 http://www.medworm.com/index.php?rid=5538075&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04386.x AbstractPhotodynamic therapy (PDT) is an attractive therapy for non‐melanoma skin cancers including actinic keratoses (AKs) because it allows treatment of large areas; it has a high response rate and results in an excellent cosmesis. However, conventional PDT for AKs is associated with inconveniently long clinic visits and discomfort during therapy. In this article, we critically review daylight‐mediated PDT, which is a simpler and more tolerable treatment procedure for PDT. We review the effective light dose, efficacy and safety, the need for prior application of sunscreen, and potential clinical scope of daylight‐PDT. Three randomized controlled studies have shown that daylight‐mediated PDT is an effective treatment of thin AKs. Daylight‐mediated PDT is nearly pain‐free and m... Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5538075 Sun, 25 Dec 2011 06:05:34 +0100 5538075 http://www.medworm.com/index.php?rid=5524884&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04408.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5524884 Thu, 22 Dec 2011 06:03:59 +0100 5524884 http://www.medworm.com/index.php?rid=5560262&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04405.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5560262 Thu, 22 Dec 2011 05:00:00 +0100 5560262 http://www.medworm.com/index.php?rid=5538078&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04395.x Conclusions  Treatment with cold plasma did not result in higher pruritus reduction than treatment with placebo. A significant reduction of pruritus compared to no effect was found at the end of therapy in both groups. Both treatment options had similar safety profiles. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5538078 Thu, 22 Dec 2011 05:00:00 +0100 5538078 http://www.medworm.com/index.php?rid=5538077&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04401.x Conclusions  Serum leptin displays an association with obesity and insulin resistance. Assessment of HOMA‐IR in patients with skin tags may serve as a useful approach for diagnosis of insulin resistance. Waist circumference is the only criteria of metabolic syndrome that correlates with number of skin tags. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5538077 Thu, 22 Dec 2011 05:00:00 +0100 5538077 http://www.medworm.com/index.php?rid=5538076&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04405.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5538076 Thu, 22 Dec 2011 05:00:00 +0100 5538076 http://www.medworm.com/index.php?rid=5524887&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04394.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5524887 Wed, 21 Dec 2011 05:00:00 +0100 5524887 http://www.medworm.com/index.php?rid=5524886&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04396.x Conclusions  The results of our study suggest that acrochordons may represent a cutaneous sign for impaired carbohydrate or lipid metabolism, liver enzyme abnormalities and hypertension. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5524886 Wed, 21 Dec 2011 05:00:00 +0100 5524886 http://www.medworm.com/index.php?rid=5524885&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04402.x Conclusion  Generalized GA showed weak improvement after treatment with a high recurrence rate. Only localized forms showed notable improvement in a more than half of treated lesions. Thus, PDL could be proposed as an alternative approach, but only for localized forms of GA. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5524885 Wed, 21 Dec 2011 05:00:00 +0100 5524885 http://www.medworm.com/index.php?rid=5524895&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04373.x Conclusion  Primary efficacy objectives were not met in the studies reported herein. Possible reasons for failure to achieve significant outcomes include insufficient length of treatment; stringency of primary endpoint and severity of nail involvement of study population. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5524895 Tue, 20 Dec 2011 05:00:00 +0100 5524895 http://www.medworm.com/index.php?rid=5524894&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04385.x Conclusion  Aggressive irradiation using QS lasers resulted in a high PIH incidence, while having no advantage in efficacy. For darker skin types, mild irradiation reduces the PIH risk with no disadvantage in efficacy. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5524894 Tue, 20 Dec 2011 05:00:00 +0100 5524894 http://www.medworm.com/index.php?rid=5524893&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04390.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5524893 Tue, 20 Dec 2011 05:00:00 +0100 5524893 http://www.medworm.com/index.php?rid=5524892&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04399.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5524892 Tue, 20 Dec 2011 05:00:00 +0100 5524892 http://www.medworm.com/index.php?rid=5524891&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04400.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5524891 Tue, 20 Dec 2011 05:00:00 +0100 5524891 http://www.medworm.com/index.php?rid=5524890&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04403.x AbstractBackground  Atopic dermatitis (AD; OMIM#603165) and psoriasis (OMIM#177900) are two common inflammatory skin disorders. Both are genetically complex, multifactorial and do not follow a Mendelian pattern of inheritance. Both diseases share several genetic susceptibility loci such as the epidermal differentiation complex (EDC) on chromosome 1q21. Within the EDC, mutations in the filaggrin (FLG) gene are strongly associated with AD whereas no association has been replicated with psoriasis. However, reduced levels of filaggrin have been reported in psoriatic skin. Further, filaggrin deficiency was shown to be a modifying factor for the phenotype in another epidermal skin disorder, X‐linked recessive ichthyosis. Altogether, this raises the question if FLG mutations may modify the di... Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5524890 Tue, 20 Dec 2011 05:00:00 +0100 5524890 http://www.medworm.com/index.php?rid=5524889&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04398.x Conclusion  Imatinib mesylate may be an effective drug in the treatment of skin fibrosis in moderate to severe NSF cases, even at reduced doses. We found a positive clinical effect on the skin, but no convincing improvement of the joint mobility. Only few patients could be recruited limiting the interpretation and conclusions of the results. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5524889 Tue, 20 Dec 2011 05:00:00 +0100 5524889 http://www.medworm.com/index.php?rid=5524888&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04404.x Conclusions  Single‐agent oral etoposide is an effective treatment option and is acceptably toxic and easily administered. Therefore, we recommend the single agent of oral etoposide as the first‐line chemotherapy for advanced CKS. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5524888 Tue, 20 Dec 2011 05:00:00 +0100 5524888 http://www.medworm.com/index.php?rid=5515565&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04392.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5515565 Mon, 19 Dec 2011 05:52:25 +0100 5515565 http://www.medworm.com/index.php?rid=5524897&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04393.x Conclusion  Our results strongly support the role of VEGF gene polymorphism in the pathogenesis of psoriasis. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5524897 Mon, 19 Dec 2011 05:00:00 +0100 5524897 http://www.medworm.com/index.php?rid=5524896&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04383.x Conclusion  In our experience, patches were more prevalent among childhood MF cases. Overrepresentation of hypopigmented and purpuric lesions was remarkable. Progression to an advanced stage was not seen. However, recurrences after discontinuation of therapy were common. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5524896 Mon, 19 Dec 2011 05:00:00 +0100 5524896 http://www.medworm.com/index.php?rid=5515570&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04384.x Conclusion  This was the first study to report the significant correlations between the casual sebum level and the number, proportion and location of acne lesions in a large acne patients group, using an objective, bioengineering method. Moreover, we also found that the influence of sebum was prominent on the inflammatory lesions. In addition, both age and gender influenced the correlation between the casual sebum level and the acne. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5515570 Sat, 17 Dec 2011 05:00:00 +0100 5515570 http://www.medworm.com/index.php?rid=5515569&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04387.x Conclusion  This study indicates that some urticaria patients, especially those with unknown causes or with an H1‐antihistamine‐resistant disease, may benefit from a referral to tertiary care centres. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5515569 Sat, 17 Dec 2011 05:00:00 +0100 5515569 http://www.medworm.com/index.php?rid=5515568&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04388.x Conclusion  The severe type of hair loss in patient with SLE presents a unique set of clinical, dermoscopic and histopathological features. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5515568 Sat, 17 Dec 2011 05:00:00 +0100 5515568 http://www.medworm.com/index.php?rid=5515567&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04389.x Conclusion  As the first report of a large series of sporotrichosis cases from China to be published in English literature, our study indicated a serious sporotrichosis endemic situation in Jilin province, Northeast China, with epidemiological and clinical characteristics similar to those of previous Chinese reports, but different from those in other countries. KI, itraconazole and terbinafine are effective for the treatment. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5515567 Sat, 17 Dec 2011 05:00:00 +0100 5515567 http://www.medworm.com/index.php?rid=5515566&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04391.x Conclusion  Rituximab is effective in treating resistant and severe pemphigus in Indian patients. Acute complications can occur during rituximab infusion and require close monitoring. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5515566 Sat, 17 Dec 2011 05:00:00 +0100 5515566 http://www.medworm.com/index.php?rid=5504992&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04382.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5504992 Fri, 16 Dec 2011 06:11:23 +0100 5504992 http://www.medworm.com/index.php?rid=5504991&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04381.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5504991 Fri, 16 Dec 2011 06:11:21 +0100 5504991 http://www.medworm.com/index.php?rid=5504990&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04000.x Conclusion  In this study, skin pain and skin discomfort were significantly related to HRQoL when controlling for demographic and clinical characteristics. In addition, sleep disturbance mediated the association between skin pain and HRQoL. An understanding of the complex association among physiological and psychological factors, and HRQoL is clinically important in order to provide proper treatment and care of patients with psoriasis. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5504990 Fri, 16 Dec 2011 06:10:45 +0100 5504990 http://www.medworm.com/index.php?rid=5486960&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04368.x Conclusion  The study’s findings demonstrate that the studied hypopigmented (vitiligo, hypopigmented MF, hypopigmented TV) disorders show similar changes in their cutaneous microenvironment with increased TNF‐α and decreased bFGF mRNA expression. This cytokine microenvironment change may be implicated in the pigment loss and hence these cytokines may have future therapeutic implications. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5486960 Thu, 08 Dec 2011 05:00:00 +0100 5486960 http://www.medworm.com/index.php?rid=5486959&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04370.x Conclusion  The diagnostic and therapeutic management of csU by private practice physicians does not sufficiently comply with the guidelines. Awareness of the guidelines can lead to improved care. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5486959 Thu, 08 Dec 2011 05:00:00 +0100 5486959 http://www.medworm.com/index.php?rid=5486961&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04371.x Conclusion  The Chinese version of DLQI is a reliable and valid measure to assess patient‐reported impact of skin disease and could be used in QoL and health outcome studies on Chinese psoriasis patients. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5486961 Wed, 07 Dec 2011 05:00:00 +0100 5486961 http://www.medworm.com/index.php?rid=5476689&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04359.x Conclusions  The European Council resolutions regarding safety of tattoo inks are not effective. Stock bottles of tattoo ink may contain bacteria pathogenic to humans and environmental bacteria, and packaging, labelling and preservation of inks are of inadequate quality. Claim of sterility can be erroneous. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5476689 Wed, 07 Dec 2011 05:00:00 +0100 5476689 http://www.medworm.com/index.php?rid=5476688&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04362.x Conclusion  Our study illustrates the poor prognosis of pemphigus by a long duration to disease control, a high initial dose of oral steroid, a high rate of relapse and a short remission period. Only mucosal involvement at presentation was identified as a poor prognostic factor. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5476688 Wed, 07 Dec 2011 05:00:00 +0100 5476688 http://www.medworm.com/index.php?rid=5476692&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04358.x Conclusions  Both treatments were equally effective in the induction of skin tolerance to sunlight in PLE patients. However, the home treatment was much better accepted than the treatment in the hospital. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5476692 Tue, 06 Dec 2011 05:00:00 +0100 5476692 http://www.medworm.com/index.php?rid=5476691&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04360.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5476691 Tue, 06 Dec 2011 05:00:00 +0100 5476691 http://www.medworm.com/index.php?rid=5476690&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04372.x Conclusion  Differential TLR4/2 gene expressions on psoriatic peripheral blood mononuclear cells and correlations with regulatory and/or proinflammatory cytokines and/or damage‐associated molecular pattern molecule S100A9 emphasize innate immune response role in psoriasis. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5476690 Tue, 06 Dec 2011 05:00:00 +0100 5476690 http://www.medworm.com/index.php?rid=5494975&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04356.x Conclusions  This position article summarizes those discussions and makes recommendations concerning a standardized protocol for treating OTRs, for a large randomized controlled trial to provide robust data on safety, efficacy and optimal pain control, and to provide pharmaco‐economics data that can be used to support extended reimbursement in this patient group. The authors also recommend a second clinical trial to further investigate induced immunosuppression with PDT in healthy volunteers. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5494975 Thu, 01 Dec 2011 05:00:00 +0100 5494975 http://www.medworm.com/index.php?rid=5486958&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04349.x Conclusion  This article provides useful and practical considerations for the management and treatment of patients with moderate to severe skin and nail psoriasis. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5486958 Thu, 01 Dec 2011 05:00:00 +0100 5486958 http://www.medworm.com/index.php?rid=5476687&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04364.x Conclusions  This prospective and comparative study is, to our knowledge, the first to report the frequency of SpSA in stage IV melanoma. Our results suggest that spontaneous autoimmunity, through a rupture of self‐tolerance, is a good prognostic factor in a subgroup of patients with stage IV melanoma. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5476687 Thu, 01 Dec 2011 05:00:00 +0100 5476687 http://www.medworm.com/index.php?rid=5457871&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04361.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5457871 Thu, 01 Dec 2011 05:00:00 +0100 5457871 http://www.medworm.com/index.php?rid=5457874&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04353.x Conclusions  Available evidence from prospective, uncontrolled clinical trials indicates short‐term hair removal efficacy of currently available home‐use light‐based hair removal devices. Additional controlled trials will be helpful to substantiate the efficacy and to better predict the incidence of adverse events associated with optical home‐use hair removal. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5457874 Wed, 30 Nov 2011 05:00:00 +0100 5457874 http://www.medworm.com/index.php?rid=5457873&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04365.x Conclusion  Mastocytosis in children usually has a benign course. Nevertheless, severe mediator‐related symptoms and systemic involvement may appear. Therefore, a multidisciplinary approach involving careful monitoring of the serum tryptase level, SCORMA Index and the organ function is recommended. Both tryptase levels and the SCORMA Index are of a great value as disease severity parameters and they should be assessed simultaneously in all mastocytosis patients. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5457873 Wed, 30 Nov 2011 05:00:00 +0100 5457873 http://www.medworm.com/index.php?rid=5457872&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04357.x Conclusion  In terms of cost‐efficacy, the most efficient biological drug was adalimumab. The robustness of this finding was confirmed by sensitivity analysis. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5457872 Wed, 30 Nov 2011 05:00:00 +0100 5457872 http://www.medworm.com/index.php?rid=5457879&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04304.x Conclusions  Dexeryl® showed a significant improvement of xerosis and related symptoms in children with ichthyosis and was well tolerated. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5457879 Mon, 28 Nov 2011 05:00:00 +0100 5457879 http://www.medworm.com/index.php?rid=5457878&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04355.x Conclusions  Darier’s disease has a negative impact on HRQL of patients and the HRQL is associated with various disease characteristics, mainly skin area affected and clinical severity. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5457878 Mon, 28 Nov 2011 05:00:00 +0100 5457878 http://www.medworm.com/index.php?rid=5457877&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04363.x Conclusion  In PV, the combination of anti‐desmoglein autoantibody‐mediated acantholysis in conjunction with secondary factors, such as inflammatory changes due to infection, may cause weakening of hair follicle anchorage resulting in hair loss and alopecic patches. This unusual clinical phenotype should alert physicians to PV as a potential diagnosis. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5457877 Mon, 28 Nov 2011 05:00:00 +0100 5457877 http://www.medworm.com/index.php?rid=5457876&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04369.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5457876 Mon, 28 Nov 2011 05:00:00 +0100 5457876 http://www.medworm.com/index.php?rid=5457875&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04367.x Conclusion  Our study provides novel information relative to the clinical details, demographic features and serological parameters of a population of vitiligo patients from Mumbai, India. Important distinctions from similar surveys conducted in European patients were evident such as an infrequency of family history, a low prevalence of clinical autoimmune disease, and an absence of particular antibody specificities. These differences may have a bearing on the pathogenesis and course of the disease in Indian patients. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5457875 Mon, 28 Nov 2011 05:00:00 +0100 5457875 http://www.medworm.com/index.php?rid=5441165&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04366.x AbstractThe patterns of acute‐phase response (APR) biomarkers differ upon various inflammatory conditions. Little information is available on the systemic inflammatory response in urticaria/angio‐oedema. It has been shown that concentrations of circulating APR biomarkers, IL‐6 and C‐reactive protein (CRP), are elevated more in severe chronic urticaria (CU) than in patients showing milder urticarial symptoms. It is not clear whether the increase of IL‐6 and CRP is merely an epiphenomenon or may contribute to the pathogenesis of CU. It is tempting to speculate that mediators of APR may enhance urticarial inflammation. In addition, there is some association between APR and activation of coagulation/fibrinolysis in CU. It is well known that even slight elevation in CRP baseline conce... Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5441165 Fri, 25 Nov 2011 05:58:54 +0100 5441165 http://www.medworm.com/index.php?rid=5441168&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04333.x Conclusion  Our data suggest a possible role for PPARγ in the pathogenesis of MF possibly through several mechanisms, one of which might be conferring upon the lymphoma cells, a survival advantage at least partially through up regulating Bcl‐2. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5441168 Thu, 24 Nov 2011 05:00:00 +0100 5441168 http://www.medworm.com/index.php?rid=5441167&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04344.x Conclusion  Our study provides evidence that the presence of dermal elastosis and cutaneous ageing may be influenced by the type of food intake: Vitamin E and C‐rich fruit and tea are positively associated with less elastosis. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5441167 Thu, 24 Nov 2011 05:00:00 +0100 5441167 http://www.medworm.com/index.php?rid=5441166&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04354.x Conclusion  Apelin may be associated with altered and activated angiogenesis prior to fibrotic responses in early SSc and with the development of proliferative vasculopathy in late stage SSc. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5441166 Thu, 24 Nov 2011 05:00:00 +0100 5441166 http://www.medworm.com/index.php?rid=5431854&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04351.x Conclusions  Antibiotic‐resistant P. acnes is prevalent in Hong Kong. Dermatologists should be more vigilant in prescribing antibiotics for acne patients. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5431854 Tue, 22 Nov 2011 06:00:17 +0100 5431854 http://www.medworm.com/index.php?rid=5431856&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04341.x Discussion  The use of the flexible blade alone in Mohs may yield jagged tissue peripheral edges after cutting on the cryostat. The classic technique with a scalpel excision often results in a deeper cut than desired, resulting in a larger defect. We modified both the traditional Mohs technique and the flexible blade by combining both. We have performed this method in approximately over 100 cases on the scalp, face and ears, preserving tissue, minimizing bleeding and avoiding alopecia. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5431856 Mon, 21 Nov 2011 05:00:00 +0100 5431856 http://www.medworm.com/index.php?rid=5431855&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04347.x Conclusion  The use of the 4‐point scale is a valid method to compare scars of non‐invasive dermatological treatments. Supplementary registering vascularity and pigmentation can be useful in future studies. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5431855 Mon, 21 Nov 2011 05:00:00 +0100 5431855 http://www.medworm.com/index.php?rid=5422249&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04348.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5422249 Sat, 19 Nov 2011 05:53:24 +0100 5422249 http://www.medworm.com/index.php?rid=5422252&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04342.x Conclusions  A higher MN count is associated with lower phototype (blonde hair and fair skin) and higher age. The mean number of MN, including those of smaller size (<2 mm), was elevated in our series, especially on intermittently exposed sites. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5422252 Sat, 19 Nov 2011 05:00:00 +0100 5422252 http://www.medworm.com/index.php?rid=5422251&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04345.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5422251 Sat, 19 Nov 2011 05:00:00 +0100 5422251 http://www.medworm.com/index.php?rid=5422250&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04346.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5422250 Sat, 19 Nov 2011 05:00:00 +0100 5422250 http://www.medworm.com/index.php?rid=5422254&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04339.x Conclusion  In our study we found low awareness for important epidemiological aspects like transmission of the disease, risk factors and prevention. Our study provides a baseline to understand and correct deficits in the perceptions and knowledge regarding CL in Saudi Arabia and would provide a template to design interventions. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5422254 Fri, 18 Nov 2011 05:00:00 +0100 5422254 http://www.medworm.com/index.php?rid=5422253&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04350.x Conclusions  Diffuse cutaneous mastocytosis, DCM is a heterogeneous, severe, cutaneous disease, associated with mediator‐related symptoms and risk of anaphylactic shock. Although our results suggest generally favourable prognosis, the review of the literature indicate that SM may occur. Therefore, more guarded prognosis should be given in DCM patients. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5422253 Fri, 18 Nov 2011 05:00:00 +0100 5422253 http://www.medworm.com/index.php?rid=5408277&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04352.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5408277 Wed, 16 Nov 2011 21:15:15 +0100 5408277 http://www.medworm.com/index.php?rid=5408276&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04336.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5408276 Wed, 16 Nov 2011 21:15:14 +0100 5408276 http://www.medworm.com/index.php?rid=5408275&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04335.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5408275 Wed, 16 Nov 2011 21:15:12 +0100 5408275 http://www.medworm.com/index.php?rid=5408274&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04278.x AbstractHair colour is one of the most conspicuous phenotypes in humans, ranging from black, brown, blond to red. This diversity arises mostly from the quantity and ratio of the black‐dark brown eumelanin and the reddish‐brown pheomelanin. To study the chemical basis underlying the diversity of hair colour, we have developed several chemical methods to quantify those two pigments. Alkaline H2O2 oxidation affords pyrrole‐2,3,5‐tricarboxylic acid (PTCA) as a eumelanin marker and thiazole‐2,4,5‐tricarboxylic acid (TTCA) as a pheomelanin marker. Pheomelanin can also be analysed as 4‐amino‐3‐hydroxyphenylalanine (4‐AHP) after hydroiodic acid hydrolysis. Using those methods, we evaluated the contents of eumelanin and pheomelanin (the ‘chemical’ phenotype) in human hairs o... Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5408274 Wed, 16 Nov 2011 21:14:33 +0100 5408274 http://www.medworm.com/index.php?rid=5408265&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04338.x Conclusions  Carriage of gene SNPs is protective against the development of acne conglobata even in the presence of P. acnes. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5408265 Wed, 16 Nov 2011 21:07:57 +0100 5408265 http://www.medworm.com/index.php?rid=5408266&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04343.x Conclusions  The correlation between antioxidant levels and clinical phototype confirmed the hypothesis that other factors than melanin determine largely the minimal erythema dose values in vitiligo lesional skin. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5408266 Tue, 15 Nov 2011 05:00:00 +0100 5408266 http://www.medworm.com/index.php?rid=5408268&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04340.x Conclusion  Serum sCD26 levels, combined with serum TARC levels, are helpful in diagnosis of AD, CTCL and psoriasis. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5408268 Mon, 14 Nov 2011 05:00:00 +0100 5408268 http://www.medworm.com/index.php?rid=5408267&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04327.x Conclusion  Compression was shown to be feasible for elderly community care patients in Hong Kong and is currently implemented as part of standard venous leg ulcer treatment. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5408267 Mon, 14 Nov 2011 05:00:00 +0100 5408267 http://www.medworm.com/index.php?rid=5400843&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04325.x Conclusions  In clinical practice, ustekinumab is effective both in biologic‐naÿve patients and as salvage therapy when other biological treatments have failed. The response rates prior to the third injection in our series were better in patients weighing ≤ 100 kg and in those without previous exposure to biologics. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5400843 Sun, 13 Nov 2011 05:50:28 +0100 5400843 http://www.medworm.com/index.php?rid=5400845&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04332.x Conclusion  Topical WBI‐1001 induces rapid and significant improvement in patients with plaque psoriasis. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5400845 Sat, 12 Nov 2011 05:00:00 +0100 5400845 http://www.medworm.com/index.php?rid=5400844&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04337.x Conclusions  Melasma skin is characterized by impaired stratum corneum integrity and a delayed barrier recovery rate. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5400844 Sat, 12 Nov 2011 05:00:00 +0100 5400844 http://www.medworm.com/index.php?rid=5387036&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04296.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5387036 Thu, 10 Nov 2011 07:20:27 +0100 5387036 http://www.medworm.com/index.php?rid=5387006&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04334.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5387006 Thu, 10 Nov 2011 07:13:20 +0100 5387006 http://www.medworm.com/index.php?rid=5387008&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04329.x Conclusions  Acne prevalence is high among adolescents in Eskisehir but the rate of consulting doctor is low. Increasing public awareness is critical for convincing adolescents to seek medical help earlier. Acne was related with dietary habits. Fat, sugar and fast food consumption is found to be positively correlated with acne prevalence. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5387008 Thu, 10 Nov 2011 05:00:00 +0100 5387008 http://www.medworm.com/index.php?rid=5387007&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04331.x Conclusion  Dead Sea climatotherapy is a particularly effective treatment method for the sub‐population of adults with severe AD. The SCORAD 75 can be useful for defining sub‐populations in which treatment is more likely to be successful. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5387007 Thu, 10 Nov 2011 05:00:00 +0100 5387007 http://www.medworm.com/index.php?rid=5387009&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04330.x Conclusion  We have found the characteristics of acne scar through the serial sections of several atrophic scars, and suggest that the treatment must reflect several considerations, including the understanding of histopathological findings and the use of combination therapy. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5387009 Sat, 05 Nov 2011 04:00:00 +0100 5387009 http://www.medworm.com/index.php?rid=5387010&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04309.x Conclusion  Our study found a novel mutation in exon 10 of CYLD gene. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5387010 Fri, 04 Nov 2011 04:00:00 +0100 5387010 http://www.medworm.com/index.php?rid=5387015&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04282.x Conclusion  Long‐pulsed Nd : YAG laser can be considered as another effective and safe treatment modality for stubborn telangeictasia even on face, if applied cautiously. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5387015 Thu, 03 Nov 2011 04:00:00 +0100 5387015 http://www.medworm.com/index.php?rid=5387014&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04326.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5387014 Thu, 03 Nov 2011 04:00:00 +0100 5387014 http://www.medworm.com/index.php?rid=5387013&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04328.x Conclusion  The clinical and histopathological features of the CRP patients in our study are generally comparable to those published in the literature, with minor differences. Clinically, one case had an atypical clinical presentation, and microscopically follicular plugging was seen in the majority of cases. Yeast‐like spores were seen in six cases further supporting a role of Malassezia furfur in the pathogenesis of CRP. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5387013 Thu, 03 Nov 2011 04:00:00 +0100 5387013 http://www.medworm.com/index.php?rid=5387012&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04315.x Conclusion C. parapsilosis was the most common fungal species isolated from patients with onychomycosis. The different response obtained by in vitro susceptibility testing to drugs shows the importance of these methods to assist clinicians in choosing the best therapeutic option. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5387012 Thu, 03 Nov 2011 04:00:00 +0100 5387012 http://www.medworm.com/index.php?rid=5387011&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04288.x Conclusions  Our findings indicate that if NLP is correctly diagnosed and appropriately treated. Nail biopsy is proven to be a relatively simple, safe and useful procedure with a minimal scarring risk. Long‐term observation indicates that the prognosis of NLP is poor with high rate of relapses, with permanent damage to the nail unit. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5387011 Thu, 03 Nov 2011 04:00:00 +0100 5387011 http://www.medworm.com/index.php?rid=5387018&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04285.x Conclusions  Mucosal and hepatic involvement was frequent in cases with a high number of cutaneous haemangiomas (>100), but only frequency of mucosal involvement was statistically significant (P = 0.021). (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5387018 Wed, 02 Nov 2011 04:00:00 +0100 5387018 http://www.medworm.com/index.php?rid=5387017&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04316.x Conclusions  Male skin colour homogeneity, driven by melanin and haemoglobin distribution, influences perception of age, health and attractiveness. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5387017 Wed, 02 Nov 2011 04:00:00 +0100 5387017 http://www.medworm.com/index.php?rid=5387016&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04319.x Conclusion  The significant decrease in the IL‐6 level after therapy suggests that blocking of IL‐6 could have therapeutic benefits for the treatment of PV, particularly in severe forms. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5387016 Wed, 02 Nov 2011 04:00:00 +0100 5387016 http://www.medworm.com/index.php?rid=5387019&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04323.x Conclusions  We found distinctive dermoscopic signs that are exclusive to distal subungual onychomycosis and to traumatic onycholysis. Detection of these signs is simple and can, in selected cases, help to avoid mycology. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5387019 Tue, 01 Nov 2011 04:00:00 +0100 5387019 http://www.medworm.com/index.php?rid=5387029&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04297.x Conclusion  Follow‐up frequency was higher than recommended by the current melanoma guideline in a large group of patients, mainly those with lower Breslow thickness. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5387029 Mon, 31 Oct 2011 04:00:00 +0100 5387029 http://www.medworm.com/index.php?rid=5387028&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04298.x Conclusion  Skin type appears to be a significant factor in psychological morbidity in acne. The FSPC is a reliable method for assessing skin phenotype, even when elicited via a concise questionnaire item suitable for assessing skin type as a potential confounder in studies of other outcome factors. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5387028 Mon, 31 Oct 2011 04:00:00 +0100 5387028 http://www.medworm.com/index.php?rid=5387027&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04318.x Conclusion  Being a systemic vasculitis, BD may cause cardiovascular involvement. In this study, dyslipidemia, insulin resistance and low adiponectin levels were not detected among our patients with Behçet’s disease. Our results suggest that there exists no increased risk for atherosclerotic cardiovascular disease associated with adiponectin levels and insulin resistance in patients with Behçet’s disease. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5387027 Mon, 31 Oct 2011 04:00:00 +0100 5387027 http://www.medworm.com/index.php?rid=5387026&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04308.x Conclusions  Greater improvements in PROs specific to skin disorders were seen with etanercept BIW than QW at Week 12, but not at Week 24. Both etanercept regimens led to sustained PRO improvements, starting as early as Week 3. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5387026 Mon, 31 Oct 2011 04:00:00 +0100 5387026 http://www.medworm.com/index.php?rid=5387025&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04314.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5387025 Mon, 31 Oct 2011 04:00:00 +0100 5387025 http://www.medworm.com/index.php?rid=5387024&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04317.x Conclusion  The presence of white shiny lines of any length accompanied by white shiny areas is most suggestive of a diagnosis of BCC (P < 0.001). Melanomas are more likely to display short white shiny lines in an orthogonal distribution (P < 0.001) and without white shiny areas. Actinic tumours are most likely to exhibit rosettes (P < 0.001). (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5387024 Mon, 31 Oct 2011 04:00:00 +0100 5387024 http://www.medworm.com/index.php?rid=5387023&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04320.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5387023 Mon, 31 Oct 2011 04:00:00 +0100 5387023 http://www.medworm.com/index.php?rid=5387022&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04321.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5387022 Mon, 31 Oct 2011 04:00:00 +0100 5387022 http://www.medworm.com/index.php?rid=5387021&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04322.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5387021 Mon, 31 Oct 2011 04:00:00 +0100 5387021 http://www.medworm.com/index.php?rid=5387020&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04324.x Conclusions  Topical pre‐treatment with phytomenadione cream might become useful in epidermal growth factor inhibitor‐associated acneiform eruptions. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5387020 Mon, 31 Oct 2011 04:00:00 +0100 5387020 http://www.medworm.com/index.php?rid=5360487&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04305.x Conclusion  This model suggests that CPS is cost‐effective in maintaining the success achieved in moderate scalp psoriasis patients. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5360487 Mon, 31 Oct 2011 03:56:29 +0100 5360487 http://www.medworm.com/index.php?rid=5360488&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04204.x Conclusions  The clinical, histological and immunopathological characteristics of Chinese patients with DH are similar to those seen in Caucasian populations. The positive rates of anti‐EMA and anti‐tTG antibodies were lower compared with those seen in Western countries. DH is not extremely rare in China and should be actively investigated. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5360488 Thu, 27 Oct 2011 04:00:00 +0100 5360488 http://www.medworm.com/index.php?rid=5347649&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04225.x Conclusion  Adalimumab was safe, well‐tolerated and effective for treatment of active plaque psoriasis in patients who had not adequately responded to prior therapy. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5347649 Wed, 26 Oct 2011 11:46:43 +0100 5347649 http://www.medworm.com/index.php?rid=5347653&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04306.x Conclusion  Increased expression of COX‐2 and decreased expression of miR‐26b in OLP suggests both to play a role in OLP. COX‐2 has been connected to both malignant development and autoimmunity but as malignant development of OLP is quite rare we suggest that the increased levels of COX‐2 seen here support an autoimmune cause of the disease. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5347653 Mon, 24 Oct 2011 04:00:00 +0100 5347653 http://www.medworm.com/index.php?rid=5347652&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04310.x AbstractPapulopustular rosacea (PPR) is a common facial skin disease, characterized by erythema, telangiectasia, papules and pustules. Its physiopathology is still being discussed, but recently several molecular features of its inflammatory process have been identified: an overproduction of Toll‐Like receptors 2, of a serine protease, and of abnormal forms of cathelicidin.The two factors which stimulate the Toll‐like receptors to induce cathelicidin expression are skin infection and cutaneous barrier disruption: these two conditions are, at least theoretically, fulfilled by Demodex, which is present in high density in PPR and creates epithelial breaches by eating cells. So, the major pathogenic mechanisms of Demodex and its role in PPR are reviewed here in the context of these recent d... Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5347652 Mon, 24 Oct 2011 04:00:00 +0100 5347652 http://www.medworm.com/index.php?rid=5347651&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04312.x AbstractBackground  FDG PET‐CT is the superior imaging modality for the detection of visceral metastases (M+) in patients with melanoma. Conflicting evidence exists regarding its role for the initial staging of patients with high risk localized melanoma (large Breslow Thickness (BT) and/or ulceration).Objective  To assess the role of routine staging with FDG PET‐CT in melanoma patients with localized high risk melanoma.Methods  Forty‐eight consecutive patients with 1 < BT < 4 mm with ulceration and with BT ≥ 4 mm were staged with PET‐CT. PET‐CT procedures were performed on a GE Discovery ST® scanner. PET‐CT findings for regional nodal status and presence of distant metastatic disease were collected. The gold standard for nodal assessment was patho... Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5347651 Mon, 24 Oct 2011 04:00:00 +0100 5347651 http://www.medworm.com/index.php?rid=5347650&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04313.x Conclusion  Considering the populations size of Southern Sardinia, is plausible that 1.5/100 000 Sardinian will be affected by allopurinol related ADR per year. Advanced age, and inappropriate allopurinol prescription were the main conditions affecting morbidity and mortality. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5347650 Mon, 24 Oct 2011 04:00:00 +0100 5347650 http://www.medworm.com/index.php?rid=5336006&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04262.x Conclusion  The number of scientific publications in the field of dermoscopy has increased significantly over the past 25 years. Italy, the United States and Austria have dominated the field of dermoscopy. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5336006 Sat, 22 Oct 2011 04:59:36 +0100 5336006 http://www.medworm.com/index.php?rid=5336008&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04292.x Conclusions  Estroprogestins represent an effective and safe treatment in women with acne and polycystic ovary syndrome (PCOS). Nevertheless, the combination EE 30 mcg/DRSP 3 mg appears to be a more potent therapeutic option. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5336008 Wed, 19 Oct 2011 04:00:00 +0100 5336008 http://www.medworm.com/index.php?rid=5336007&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04311.x (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5336007 Wed, 19 Oct 2011 04:00:00 +0100 5336007 http://www.medworm.com/index.php?rid=5324092&cid=s_38739_12_f&fid=38739&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1468-3083.2011.04307.x Conclusions  Physicians treating patients with psoriasis must be aware of physical, psychological and social aspects of the disease and need to use a multidimensional approach. (Source: Journal of the European Academy of Dermatology and Venereology) Journal of the European Academy of Dermatology and Venereology journals http://www.medworm.com/rss/comments.php?id=5324092 Tue, 18 Oct 2011 05:14:49 +0100 5324092