MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Korean J Hepatol' source. Sun, 31 Oct 2010 10:09:52 +0100 http://www.medworm.com/index.php?rid=4053671&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20924208%26dopt%3DAbstract Authors: Jang JY, Chung RT Treatments for chronic hepatitis C has evolved significantly in the past 15 years. The standard of care (SOC) is peginterferon alfa-2a/-2b with ribavirin for 48 weeks or 24 weeks in patients infected with HCV genotype 1 or 2/3, respectively. The treatment duration can be individualized based on the baseline viral load and the speed of the virologic response during treatment. However, current therapies are associated with side effects, complications, and poor patient tolerability. Therefore, there is an urgent need to identify better strategies for treating this disease. An improved sustained virologic response (SVR) can be achieved with new HCV-specific inhibitors against NS3/4A and NS5B polymerases. Recent trials have found SVR rates in patients with HCV gen... Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=4053671 Tue, 31 Aug 2010 23:00:00 +0100 4053671 http://www.medworm.com/index.php?rid=4053670&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20924209%26dopt%3DAbstract Authors: Kim JW PMID: 20924209 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=4053670 Tue, 31 Aug 2010 23:00:00 +0100 4053670 http://www.medworm.com/index.php?rid=4053669&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20924210%26dopt%3DAbstract CONCLUSIONS: These data suggest that adenovirus-mediated inhibition of HIF-1α inhibits the invasion, tube formation, and cell growth in HUVECs and HCC cells. PMID: 20924210 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=4053669 Tue, 31 Aug 2010 23:00:00 +0100 4053669 http://www.medworm.com/index.php?rid=4053668&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20924211%26dopt%3DAbstract CONCLUSIONS: The role of prohepcidin may differ in different human liver diseases. In the setting of CH-C, both the serum prohepcidin and IL-6 levels were significantly elevated and were positively correlated with each other. PMID: 20924211 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=4053668 Tue, 31 Aug 2010 23:00:00 +0100 4053668 http://www.medworm.com/index.php?rid=4053667&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20924212%26dopt%3DAbstract CONCLUSIONS: While most patients with acute hepatitis A have an uncomplicated clinical course, our data suggest that a more-severe clinical course is correlated with being older, significant alcohol intake, and chronic hepatitis-B-virus infection. PMID: 20924212 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=4053667 Tue, 31 Aug 2010 23:00:00 +0100 4053667 http://www.medworm.com/index.php?rid=4053666&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20924213%26dopt%3DAbstract CONCLUSIONS: The accuracy in predicting acute kidney injury and short-term mortality was higher for a serum cystatin C level of >1.23 mg/L than for the serum creatinine concentration in patients with cirrhosis. PMID: 20924213 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=4053666 Tue, 31 Aug 2010 23:00:00 +0100 4053666 http://www.medworm.com/index.php?rid=4053665&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20924214%26dopt%3DAbstract CONCLUSIONS: Alcohol intake might not increase the risk of HCC in patients with HBV infection. PMID: 20924214 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=4053665 Tue, 31 Aug 2010 23:00:00 +0100 4053665 http://www.medworm.com/index.php?rid=4053664&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20924215%26dopt%3DAbstract CONCLUSIONS: A 48-week dosing with clevudine 30 mg daily was superior to lamivudine 100 mg daily in suppressing HBV replication, with no emergence of viral breakthrough in patients with HBeAg positive chronic hepatits B. PMID: 20924215 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=4053664 Tue, 31 Aug 2010 23:00:00 +0100 4053664 http://www.medworm.com/index.php?rid=4053663&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20924216%26dopt%3DAbstract We describe moderate hyperbilirubinemia in a 28-year-old man who suffered from gallstones and splenomegaly, with combined disorders of hereditary spherocytosis (HS) and Gilbert's syndrome (GS). Since it is difficult to diagnose HS in the absence of signs of anemia, we evaluated both the genetic mutation in the UGT1A1 gene and abnormalities in the erythrocyte membrane protein; the former was heterozygous for a UGT1A1 allele with three mutations and the latter was partially deficient in ankyrin expression. This is the first report of the concomitance of HS and GS with three heterozygous mutations [T-3279G, A (TA)7TAA, and G211A] in the UGT1A1 gene. PMID: 20924216 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=4053663 Tue, 31 Aug 2010 23:00:00 +0100 4053663 http://www.medworm.com/index.php?rid=4053662&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20924217%26dopt%3DAbstract Authors: Park SK, Kim YS, Kim SG, Jang JY, Moon JH, Lee MS, Kim BS, Koh ES, Park JM Intrahepatic cholangiocarcinoma is a rare malignancy that originates from the epithelial cells of the intrahepatic bile ducts. Intrahepatic cholangiocarcinoma can metastasize in lymphatic chains, including the hepatoduodenal ligament, and it often invades adjacent organs or metastasizes to other visceral organs such as the lungs, bones, adrenal glands, and brain. However, distant skeletal muscle metastasis is very rare. Moreover, a metastatic skeletal muscle tumor rarely shows specific symptoms, making it difficult to identify in a routine examination. A 45-year-old man with a chief complaint of right upper quadrant abdominal pain was admitted to our hospital. Abdominal ultrasound and computed tomograph... Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=4053662 Tue, 31 Aug 2010 23:00:00 +0100 4053662 http://www.medworm.com/index.php?rid=4053661&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20924218%26dopt%3DAbstract We report three cases of severely cholestatic hepatitis A, who showed favorable responses to oral corticosteroids. Thirty milligram of prednisolone was initiated and tapered according to the responses. Rapid improvement was observed in all cases without side effects. We suggest that corticosteroid administration can be useful in hepatitis A patients with severe cholestasis who do not show improvement by conservative managements. Clinical trial will be needed to evaluate effectiveness of corticosteroids in these patients. PMID: 20924218 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=4053661 Tue, 31 Aug 2010 23:00:00 +0100 4053661 http://www.medworm.com/index.php?rid=4053660&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20924219%26dopt%3DAbstract Authors: Kim H, Park YN PMID: 20924219 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=4053660 Tue, 31 Aug 2010 23:00:00 +0100 4053660 http://www.medworm.com/index.php?rid=4053659&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20924220%26dopt%3DAbstract Authors: Shin YM PMID: 20924220 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=4053659 Tue, 31 Aug 2010 23:00:00 +0100 4053659 http://www.medworm.com/index.php?rid=4053658&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20924221%26dopt%3DAbstract Authors: Jang JW PMID: 20924221 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=4053658 Tue, 31 Aug 2010 23:00:00 +0100 4053658 http://www.medworm.com/index.php?rid=3867214&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20606494%26dopt%3DAbstract Authors: Song BC PMID: 20606494 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3867214 Mon, 31 May 2010 23:00:00 +0100 3867214 http://www.medworm.com/index.php?rid=3867213&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20606495%26dopt%3DAbstract Authors: Kim KH Infection of hepatitis B virus (HBV) is a main cause of liver diseases including hepatitis, cirrhosis and hepatocellular carcinoma (HCC). Among the HBV-encoded proteins, the HBV X protein (HBx) has been suspected to be strongly involved in HBV-associated liver pathogenesis. HBx, a virally encoded multifunctional regulator, has been shown to induce apoptosis, anti-apoptosis, proliferation, and transformation of cells depending on the cell lines, model systems used, assay protocols, and research groups. Among the several activities of HBx, the pro-apoptotic function of HBx will be discussed in this review. Given that the disruption of apoptosis pathway by HBx contributes to the liver pathogenesis, a better understanding of the molecular interference in the cellular pro-ap... Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3867213 Mon, 31 May 2010 23:00:00 +0100 3867213 http://www.medworm.com/index.php?rid=3867212&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20606496%26dopt%3DAbstract CONCLUSIONS: This study reveals that age, GGT, and albumin are clinical factors influencing LSM values. This reinforces the need to interpret LSM values in the context of a defined diagnosis, biochemical data, radiologic examination, and other clinical findings. PMID: 20606496 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3867212 Mon, 31 May 2010 23:00:00 +0100 3867212 http://www.medworm.com/index.php?rid=3867211&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20606497%26dopt%3DAbstract CONCLUSIONS: Gas-forming liver abscesses are not uncommon in cases of pyogenic liver abscesses and are associated with high morbidity and mortality rates. The clinical manifestations and complications do not differ significantly between DM and non-DM patients. PMID: 20606497 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3867211 Mon, 31 May 2010 23:00:00 +0100 3867211 http://www.medworm.com/index.php?rid=3867210&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20606498%26dopt%3DAbstract CONCLUSIONS: Most patients diagnosed as PBC were asymptomatic, and these patients had a favorable short-term prognosis. The prognosis of PBC was dependent on the initial severity of liver disease. PMID: 20606498 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3867210 Mon, 31 May 2010 23:00:00 +0100 3867210 http://www.medworm.com/index.php?rid=3867209&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20606499%26dopt%3DAbstract CONCLUSIONS: We suspect that VBT is mostly associated with genotypic resistance to ETV. However, nonresponse might be associated with the continuance or reselection of the YMDD mutant in LAM-experienced patients. PMID: 20606499 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3867209 Mon, 31 May 2010 23:00:00 +0100 3867209 http://www.medworm.com/index.php?rid=3867208&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20606500%26dopt%3DAbstract CONCLUSIONS: The frequency of ISDR mutations was low in our cohort of Korean patients infected with HCV-Ib. Therefore, ISDR mutations might not contribute to the response to treatment with peginterferon plus ribavirin. PMID: 20606500 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3867208 Mon, 31 May 2010 23:00:00 +0100 3867208 http://www.medworm.com/index.php?rid=3867207&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20606502%26dopt%3DAbstract We report the case of a 19-year-old male diagnosed as IPH with PVT and combined deficiencies in proteins C and S. PMID: 20606502 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3867207 Mon, 31 May 2010 23:00:00 +0100 3867207 http://www.medworm.com/index.php?rid=3867206&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20606503%26dopt%3DAbstract Authors: Bae SH, Kim DH, Bae YS, Lee KJ, Kim DW, Yoon JB, Hong JH, Kim SH Toxic hepatitis has been reported as a major cause of acute hepatitis, but its potential induction by herbal remedies and/or health foods is usually neglected. We experienced a case of toxic hepatitis associated with Polygoni multiflori, a Chinese herb commonly known as Ho-Shou-Wu. A 54-year-old woman consumed Ho-Shou-Wu for 1 month, after which she experienced fatigue and overall weakness. A diagnosis of toxic hepatitis was made based on her clinical history, the findings for viral markers and other laboratory data, and ultrasonography. Her condition improved considerably after she stopped taking Ho-Shou-Wu. However, she resumed taking Ho-Shou-Wu immediately after discharge from hospital, which aggravated her sy... Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3867206 Mon, 31 May 2010 23:00:00 +0100 3867206 http://www.medworm.com/index.php?rid=3867205&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20606504%26dopt%3DAbstract We report a case of a 33-year-old female patient with chronic hepatitis C who simultaneously developed diabetic ketoacidosis and autoimmune thyroiditis after treatment with pegylated interferon-alpha 2b and ribavirin. PMID: 20606504 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3867205 Mon, 31 May 2010 23:00:00 +0100 3867205 http://www.medworm.com/index.php?rid=3867204&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20606505%26dopt%3DAbstract Authors: Seok JY, Kim YB PMID: 20606505 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3867204 Mon, 31 May 2010 23:00:00 +0100 3867204 http://www.medworm.com/index.php?rid=3867203&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20606506%26dopt%3DAbstract Authors: Shin YM PMID: 20606506 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3867203 Mon, 31 May 2010 23:00:00 +0100 3867203 http://www.medworm.com/index.php?rid=3737875&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20606494%26dopt%3DAbstract Authors: Song BC PMID: 20606494 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3737875 Mon, 31 May 2010 23:00:00 +0100 3737875 http://www.medworm.com/index.php?rid=3737874&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20606495%26dopt%3DAbstract Authors: Kim KH Infection of hepatitis B virus (HBV) is a main cause of liver diseases including hepatitis, cirrhosis and hepatocellular carcinoma (HCC). Among the HBV-encoded proteins, the HBV X protein (HBx) has been suspected to be strongly involved in HBV-associated liver pathogenesis. HBx, a virally encoded multifunctional regulator, has been shown to induce apoptosis, anti-apoptosis, proliferation, and transformation of cells depending on the cell lines, model systems used, assay protocols, and research groups. Among the several activities of HBx, the pro-apoptotic function of HBx will be discussed in this review. Given that the disruption of apoptosis pathway by HBx contributes to the liver pathogenesis, a better understanding of the molecular interference in the cellular pro-ap... Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3737874 Mon, 31 May 2010 23:00:00 +0100 3737874 http://www.medworm.com/index.php?rid=3737873&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20606496%26dopt%3DAbstract CONCLUSIONS: This study reveals that age, GGT, and albumin are clinical factors influencing LSM values. This reinforces the need to interpret LSM values in the context of a defined diagnosis, biochemical data, radiologic examination, and other clinical findings. PMID: 20606496 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3737873 Mon, 31 May 2010 23:00:00 +0100 3737873 http://www.medworm.com/index.php?rid=3737872&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20606497%26dopt%3DAbstract CONCLUSIONS: Gas-forming liver abscesses are not uncommon in cases of pyogenic liver abscesses and are associated with high morbidity and mortality rates. The clinical manifestations and complications do not differ significantly between DM and non-DM patients. PMID: 20606497 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3737872 Mon, 31 May 2010 23:00:00 +0100 3737872 http://www.medworm.com/index.php?rid=3737871&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20606498%26dopt%3DAbstract CONCLUSIONS: Most patients diagnosed as PBC were asymptomatic, and these patients had a favorable short-term prognosis. The prognosis of PBC was dependent on the initial severity of liver disease. PMID: 20606498 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3737871 Mon, 31 May 2010 23:00:00 +0100 3737871 http://www.medworm.com/index.php?rid=3737870&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20606499%26dopt%3DAbstract CONCLUSIONS: We suspect that VBT is mostly associated with genotypic resistance to ETV. However, nonresponse might be associated with the continuance or reselection of the YMDD mutant in LAM-experienced patients. PMID: 20606499 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3737870 Mon, 31 May 2010 23:00:00 +0100 3737870 http://www.medworm.com/index.php?rid=3737869&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20606500%26dopt%3DAbstract CONCLUSIONS: The frequency of ISDR mutations was low in our cohort of Korean patients infected with HCV-Ib. Therefore, ISDR mutations might not contribute to the response to treatment with peginterferon plus ribavirin. PMID: 20606500 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3737869 Mon, 31 May 2010 23:00:00 +0100 3737869 http://www.medworm.com/index.php?rid=3737868&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20606501%26dopt%3DAbstract CONCLUSIONS: In patients with preoperative AFP level >400 ng/ml, the AFP level tended to increase above 20 ng/ml at recurrence mostly within 1 year. Hence, we proposed that these patients could be monitored by only AFP until 1 year after surgery. PMID: 20606501 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3737868 Mon, 31 May 2010 23:00:00 +0100 3737868 http://www.medworm.com/index.php?rid=3737867&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20606502%26dopt%3DAbstract We report the case of a 19-year-old male diagnosed as IPH with PVT and combined deficiencies in proteins C and S. PMID: 20606502 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3737867 Mon, 31 May 2010 23:00:00 +0100 3737867 http://www.medworm.com/index.php?rid=3737866&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20606503%26dopt%3DAbstract Authors: Bae SH, Kim DH, Bae YS, Lee KJ, Kim DW, Yoon JB, Hong JH, Kim SH Toxic hepatitis has been reported as a major cause of acute hepatitis, but its potential induction by herbal remedies and/or health foods is usually neglected. We experienced a case of toxic hepatitis associated with Polygoni multiflori, a Chinese herb commonly known as Ho-Shou-Wu. A 54-year-old woman consumed Ho-Shou-Wu for 1 month, after which she experienced fatigue and overall weakness. A diagnosis of toxic hepatitis was made based on her clinical history, the findings for viral markers and other laboratory data, and ultrasonography. Her condition improved considerably after she stopped taking Ho-Shou-Wu. However, she resumed taking Ho-Shou-Wu immediately after discharge from hospital, which aggravated her sy... Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3737866 Mon, 31 May 2010 23:00:00 +0100 3737866 http://www.medworm.com/index.php?rid=3737865&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20606504%26dopt%3DAbstract We report a case of a 33-year-old female patient with chronic hepatitis C who simultaneously developed diabetic ketoacidosis and autoimmune thyroiditis after treatment with pegylated interferon-alpha 2b and ribavirin. PMID: 20606504 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3737865 Mon, 31 May 2010 23:00:00 +0100 3737865 http://www.medworm.com/index.php?rid=3737864&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20606505%26dopt%3DAbstract Authors: Seok JY, Kim YB PMID: 20606505 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3737864 Mon, 31 May 2010 23:00:00 +0100 3737864 http://www.medworm.com/index.php?rid=3737863&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20606506%26dopt%3DAbstract Authors: Shin YM PMID: 20606506 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3737863 Mon, 31 May 2010 23:00:00 +0100 3737863 http://www.medworm.com/index.php?rid=3737862&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20606507%26dopt%3DAbstract Authors: Kim IH PMID: 20606507 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3737862 Mon, 31 May 2010 23:00:00 +0100 3737862 http://www.medworm.com/index.php?rid=3586574&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20375637%26dopt%3DAbstract Authors: Lee JM, Ahn SH PMID: 20375637 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3586574 Mon, 01 Mar 2010 00:00:00 +0100 3586574 http://www.medworm.com/index.php?rid=3586573&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20375638%26dopt%3DAbstract Authors: Lim YS Acute liver failure (ALF) is a rare condition in which rapid deterioration of liver function results in altered mentation and coagulopathy in individuals without previously recognized liver disease. The outcomes of patients with ALF vary greatly according to etiology, and the etiology of ALF varies markedly by geographical region. In Korea, about 90% of ALF are associated with etiologies that usually result in poor outcomes, including hepatitis B virus (HBV) infection and herbal remedies. The main causes of death in patients with ALF are increased intracranial pressure, systemic infection, and multi-organ failure. Recent advances in the intensive care of patients with ALF have contributed to a marked improvement in their overall survival. Emergency adult to adult living... Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3586573 Mon, 01 Mar 2010 00:00:00 +0100 3586573 http://www.medworm.com/index.php?rid=3586572&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20375639%26dopt%3DAbstract CONCLUSIONS: The results of this study indicate that the clinical condition of patients with HAV-related ALF requiring emergency LT aggravates rapidly. Prognostic parameters are not sufficient for discriminating transplant candidates in patients with fulminant hepatitis A. PMID: 20375639 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3586572 Mon, 01 Mar 2010 00:00:00 +0100 3586572 http://www.medworm.com/index.php?rid=3586571&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20375640%26dopt%3DAbstract CONCLUSIONS: The simple and reproducible NAS was found to be a useful pathologic grading system in Korean NAFLD patients. However, the proportion of borderline cases based on the NAS was high. The "wait and see" strategy is necessary for evaluating the long-term prognosis. PMID: 20375640 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3586571 Mon, 01 Mar 2010 00:00:00 +0100 3586571 http://www.medworm.com/index.php?rid=3586570&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20375641%26dopt%3DAbstract CONCLUSION: The combination therapy of PEG-IFN and ribavirin exhibited a low efficacy in cirrhotic patients with HCV infection and was associated with frequent serious complications. However, with careful management of complications, the therapy may have a considerable efficacy in some patients with cirrhosis and HCV infection. PMID: 20375641 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3586570 Mon, 01 Mar 2010 00:00:00 +0100 3586570 http://www.medworm.com/index.php?rid=3586569&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20375642%26dopt%3DAbstract CONCLUSIONS: There was no significant association between seropositivity for HBsAg or anti-HCV and PC. Further studies are warranted to clarify the association between HBV infection and PC in regions where HBV is endemic. PMID: 20375642 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3586569 Mon, 01 Mar 2010 00:00:00 +0100 3586569 http://www.medworm.com/index.php?rid=3586568&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20375643%26dopt%3DAbstract CONCLUSIONS: Entecavir therapy showed excellent efficacy in nucleoside-naive chronic hepatitis B patients. The predictors of a virologic response were an absence of HBeAg and a low baseline HBV DNA level. PMID: 20375643 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3586568 Mon, 01 Mar 2010 00:00:00 +0100 3586568 http://www.medworm.com/index.php?rid=3586567&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20375644%26dopt%3DAbstract CONCLUSIONS: The results suggest that anytime random UNa/K greater than 1.25 is an accurate, cost-effective, and convenient method for replacing 24-h UNa. Large multicentered cohort studies are needed to confirm our results. PMID: 20375644 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3586567 Mon, 01 Mar 2010 00:00:00 +0100 3586567 http://www.medworm.com/index.php?rid=3586566&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20375645%26dopt%3DAbstract We present a case of a 75-year-old female patient who experienced complicated jaundice and abdominal discomfort after taking alverine citrate. Other causes of hepatitis were ruled out and the results of the liver function test returned to normal after ceasing the drug. This is the first case report in Korea of alverine-citrate-induced hepatotoxicity. PMID: 20375645 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3586566 Mon, 01 Mar 2010 00:00:00 +0100 3586566 http://www.medworm.com/index.php?rid=3586565&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20375646%26dopt%3DAbstract We report a case of a 22-year-old woman infected by hepatitis A virus who was consequently complicated with HPS. She presented typical clinical features of acute hepatitis A, and showed clinical and biochemical improvements. However, HPS developed as a complication of acute hepatitis A and the patient died of intraperitoneal bleeding caused by hepatic decompensation and disseminated intravascular coagulation. PMID: 20375646 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3586565 Mon, 01 Mar 2010 00:00:00 +0100 3586565 http://www.medworm.com/index.php?rid=3586564&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20375648%26dopt%3DAbstract Authors: Seok JY, Kim YB PMID: 20375648 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3586564 Mon, 01 Mar 2010 00:00:00 +0100 3586564 http://www.medworm.com/index.php?rid=3586563&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20375649%26dopt%3DAbstract Authors: Shin YM PMID: 20375649 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3586563 Mon, 01 Mar 2010 00:00:00 +0100 3586563 http://www.medworm.com/index.php?rid=3454373&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20375637%26dopt%3DAbstract Authors: Lee JM, Ahn SH PMID: 20375637 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3454373 Mon, 01 Mar 2010 00:00:00 +0100 3454373 http://www.medworm.com/index.php?rid=3454372&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20375638%26dopt%3DAbstract Authors: Lim YS Acute liver failure (ALF) is a rare condition in which rapid deterioration of liver function results in altered mentation and coagulopathy in individuals without previously recognized liver disease. The outcomes of patients with ALF vary greatly according to etiology, and the etiology of ALF varies markedly by geographical region. In Korea, about 90% of ALF are associated with etiologies that usually result in poor outcomes, including hepatitis B virus (HBV) infection and herbal remedies. The main causes of death in patients with ALF are increased intracranial pressure, systemic infection, and multi-organ failure. Recent advances in the intensive care of patients with ALF have contributed to a marked improvement in their overall survival. Emergency adult to adult living... Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3454372 Mon, 01 Mar 2010 00:00:00 +0100 3454372 http://www.medworm.com/index.php?rid=3454371&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20375639%26dopt%3DAbstract CONCLUSIONS: The results of this study indicate that the clinical condition of patients with HAV-related ALF requiring emergency LT aggravates rapidly. Prognostic parameters are not sufficient for discriminating transplant candidates in patients with fulminant hepatitis A. PMID: 20375639 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3454371 Mon, 01 Mar 2010 00:00:00 +0100 3454371 http://www.medworm.com/index.php?rid=3454370&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20375640%26dopt%3DAbstract CONCLUSIONS: The simple and reproducible NAS was found to be a useful pathologic grading system in Korean NAFLD patients. However, the proportion of borderline cases based on the NAS was high. The "wait and see" strategy is necessary for evaluating the long-term prognosis. PMID: 20375640 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3454370 Mon, 01 Mar 2010 00:00:00 +0100 3454370 http://www.medworm.com/index.php?rid=3454369&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20375641%26dopt%3DAbstract CONCLUSION: The combination therapy of PEG-IFN and ribavirin exhibited a low efficacy in cirrhotic patients with HCV infection and was associated with frequent serious complications. However, with careful management of complications, the therapy may have a considerable efficacy in some patients with cirrhosis and HCV infection. PMID: 20375641 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3454369 Mon, 01 Mar 2010 00:00:00 +0100 3454369 http://www.medworm.com/index.php?rid=3454368&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20375642%26dopt%3DAbstract CONCLUSIONS: There was no significant association between seropositivity for HBsAg or anti-HCV and PC. Further studies are warranted to clarify the association between HBV infection and PC in regions where HBV is endemic. PMID: 20375642 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3454368 Mon, 01 Mar 2010 00:00:00 +0100 3454368 http://www.medworm.com/index.php?rid=3454367&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20375643%26dopt%3DAbstract CONCLUSIONS: Entecavir therapy showed excellent efficacy in nucleoside-naive chronic hepatitis B patients. The predictors of a virologic response were an absence of HBeAg and a low baseline HBV DNA level. PMID: 20375643 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3454367 Mon, 01 Mar 2010 00:00:00 +0100 3454367 http://www.medworm.com/index.php?rid=3454366&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20375644%26dopt%3DAbstract CONCLUSIONS: The results suggest that anytime random UNa/K greater than 1.25 is an accurate, cost-effective, and convenient method for replacing 24-h UNa. Large multicentered cohort studies are needed to confirm our results. PMID: 20375644 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3454366 Mon, 01 Mar 2010 00:00:00 +0100 3454366 http://www.medworm.com/index.php?rid=3454365&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20375645%26dopt%3DAbstract We present a case of a 75-year-old female patient who experienced complicated jaundice and abdominal discomfort after taking alverine citrate. Other causes of hepatitis were ruled out and the results of the liver function test returned to normal after ceasing the drug. This is the first case report in Korea of alverine-citrate-induced hepatotoxicity. PMID: 20375645 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3454365 Mon, 01 Mar 2010 00:00:00 +0100 3454365 http://www.medworm.com/index.php?rid=3454364&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20375646%26dopt%3DAbstract We report a case of a 22-year-old woman infected by hepatitis A virus who was consequently complicated with HPS. She presented typical clinical features of acute hepatitis A, and showed clinical and biochemical improvements. However, HPS developed as a complication of acute hepatitis A and the patient died of intraperitoneal bleeding caused by hepatic decompensation and disseminated intravascular coagulation. PMID: 20375646 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3454364 Mon, 01 Mar 2010 00:00:00 +0100 3454364 http://www.medworm.com/index.php?rid=3454363&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20375647%26dopt%3DAbstract We described a 20-year-old male with severe liver disease who was diagnosed with EPP based on clinical and laboratory findings. He was treated with cholestyramine resin. Six months after the treatment, he was doing well without any abdominal pain or photosensitivity. PMID: 20375647 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3454363 Mon, 01 Mar 2010 00:00:00 +0100 3454363 http://www.medworm.com/index.php?rid=3454362&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20375648%26dopt%3DAbstract Authors: Seok JY, Kim YB PMID: 20375648 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3454362 Mon, 01 Mar 2010 00:00:00 +0100 3454362 http://www.medworm.com/index.php?rid=3454361&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20375649%26dopt%3DAbstract Authors: Shin YM PMID: 20375649 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3454361 Mon, 01 Mar 2010 00:00:00 +0100 3454361 http://www.medworm.com/index.php?rid=3454360&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20375650%26dopt%3DAbstract Authors: Kwon OS PMID: 20375650 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3454360 Mon, 01 Mar 2010 00:00:00 +0100 3454360 http://www.medworm.com/index.php?rid=3444231&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20037275%26dopt%3DAbstract Authors: Chae HB, Kim JH, Kim JK, Yim HJ Hepatitis B virus (HBV) infection is the one of the most common causes of the liver diseases in Korea. Since the discovery of Australia antigen (hepatitis associated antigen, or HBsAg later), hepatitis associated antigen was tested widely. HBsAg was detected in 6.6-8.6% in 1980's. Later, it decreased to 5.7% in 1990's. Remarkably, seropositivity of the children deceased to 0.2% after the nationwide vaccination program. Although hepatitis B vaccines are highly effective, the failure rate of perinatal prophylaxis in babies born to HBsAg positive mother was reported to be 4.25%. Treatment of chronic hepatitis B was initiated after the introduction of interferon alpha. Lamivudine opened a new era of oral antiviral agent, and it has been widely used ... Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3444231 Tue, 01 Dec 2009 00:00:00 +0100 3444231 http://www.medworm.com/index.php?rid=3444230&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20037276%26dopt%3DAbstract Authors: Lim YS Chronic hepatitis C (CHC) is the third most common cause of chronic liver disease and hepatocellular carcinoma (HCC) in Korea, following hepatitis B virus (HBV) infection and alcohol. HCV prevalence among Koreans older than 40 years of age has been estimated to be 1.29%. The prevalence of CHC increases with age, with the peak prevalence at the age of 60 or older. Blood transfusions have generated no risk of HCV infection since April 1991, when routine screening for anti-HCV in blood donors was adopted in Korea. Although injection drug use seems to be one of the most important risk factors of HCV infection among young adults in urban areas, the majority of CHC patients are not associated with injection drug use. Exposure to acupuncture was identified as a significant ris... Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3444230 Tue, 01 Dec 2009 00:00:00 +0100 3444230 http://www.medworm.com/index.php?rid=3444229&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20037277%26dopt%3DAbstract Authors: Kim KA The study of the epidemiology of toxic liver injury has been limited in Korea. The number of hospitalizations for toxic liver injury has been estimated to be 2,400 persons per year. About 30~40% of fulminant hepatitis was attributed to toxic hepatitis. The frequent causative agents of toxic hepatitis in Korea are herbal medicines (34-40%), folk remedies (23-34%), and prescribed medicines (24-55%). However, the most common agents causing severe liver injury including fulminant hepatitis are herbal medicine and folk remedies. Antituberculosis drugs and acetaminophen are two common causes of fulminant hepatitis among prescribed drugs. Alcohol is one of the leading causes of chronic liver disease in Korea. No nationwide study on the epidemiology of alcoholic liver disease (... Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3444229 Tue, 01 Dec 2009 00:00:00 +0100 3444229 http://www.medworm.com/index.php?rid=3444228&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20037278%26dopt%3DAbstract Authors: Park SH Recently, obesity (BMI>or=25 kg/m2) and type II diabetes mellitus have reached epidemic proportions in Korea, and rates of nonalcoholic fatty liver disease (NAFLD) are between 10% and 25% of the general population. NAFLD in Korea is as closely associated with several components of metabolic syndrome including, obesity, hypertension, diabetes and dyslipidemia as it is in Western countries. Insulin resistance and hyperinsulinemia may play a role in the pathogenesis of fatty liver in patients with normal body weight as well as in patients with obesity. And, obesity induced accumulation of fat in the adipose tissue leads to an imbalance in the regulation of adipokines, such as downregulation of adiponectin and upregulation of retinol-binding protein 4 (RBP4) and ghrelin... Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3444228 Tue, 01 Dec 2009 00:00:00 +0100 3444228 http://www.medworm.com/index.php?rid=3444227&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20037279%26dopt%3DAbstract Authors: Jang JW Liver cirrhosis represents the final common pathway of virtually all chronic liver diseases, and is characterized by an accumulation of extracellular matrix rich in fibrillar collagens. Patients with cirrhosis are at risk of developing many potential complications. The most common complication seen in patients with liver cirrhosis is ascites, and the most lethal one is bleeding varices. Other intermediate and late stage complications include spontaneous bacterial peritonitis, hepatic encephalopathy, and hepatorenal syndrome. The mortality and morbidity attributable to liver disease in Korea have decreased continuously over the past decades, probably due to the implementation of universal vaccination and potent antiviral therapies. In addition, recent advances in the un... Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3444227 Tue, 01 Dec 2009 00:00:00 +0100 3444227 http://www.medworm.com/index.php?rid=3444226&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20037280%26dopt%3DAbstract Authors: Song IH, Kim KS Primary liver cancer, most of which is hepatocellular carcinoma (HCC), is the third common leading cancer in Korea. During the last two decades, the incidence rate of primary liver cancer has shown a modest decrease, but its mortality rate has slightly increased. The incidence of HCC, according to age, peaks in the late sixth decade in men and in the early seventh decade in women. Hepatitis B virus (HBV) is the most important risk factor, which represents approximately 70% of all HCC, and hepatitis C virus (HCV) and alcohol are the next in order of major risk factors for the development of HCC in Korea. HBV-associated HCC occurs 10 years earlier than HCV-associated HCC due to a more prolonged exposure to HBV, which is vertically transmitted almost from HBsAg-po... Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3444226 Tue, 01 Dec 2009 00:00:00 +0100 3444226 http://www.medworm.com/index.php?rid=3444225&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20037281%26dopt%3DAbstract Authors: Kim KS Since the first liver resection was carried out in Korea in 1959, there have been remarkable changes in the field of surgery. With technical advancement and the improvement of perioperative care, liver resections are widely performed and surgical mortality is approaching zero. In the early 1990s, liver transplantation evolved as a feasible option in the treatment of end-stage liver disease in Korea, with successful adult living-donor liver transplantation (LDLT) as one of the greatest achievements. Various innovations in surgical approaches have been introduced. We review the current status of hepatic surgery in liver disease in Korea. PMID: 20037281 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3444225 Tue, 01 Dec 2009 00:00:00 +0100 3444225 http://www.medworm.com/index.php?rid=3444224&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20037282%26dopt%3DAbstract Authors: Kwon SY The seroprevalence of anti-HAV (hepatitis A virus) has been decreasing in Korea. The decrease in HAV infection in young adults has resulted in the reduction of individuals with protective antibody and an increase in hepatitis A in the adult population. The increase in HAV infection in adults will have an impact on the magnitude and severity of the disease. In Korea, symptomatic hepatitis A has been gradually increasing since the mid-1990s, with a tendency toward an increase in mean age and disease severity. The endemic genotype of HAV in Korea has been changing from genotype IA alone to a mixture of genotype IA and IIIA. Therefore, preventive measures including universal vaccination in infants and active immunization of the adult population should be considered. PM... Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3444224 Tue, 01 Dec 2009 00:00:00 +0100 3444224 http://www.medworm.com/index.php?rid=3127041&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20037261%26dopt%3DAbstract Authors: Seo YS PMID: 20037261 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3127041 Tue, 01 Dec 2009 00:00:00 +0100 3127041 http://www.medworm.com/index.php?rid=3127040&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20037262%26dopt%3DAbstract Authors: Jung YK, Kim JH Acute viral hepatitis A has recently become a major public health problem in Korea, and the incidence of symptomatic hepatitis A is growing rapidly. With improvements in socioeconomic conditions and environmental hygiene, the chances of exposure to hepatitis A virus (HAV) during childhood have decreased and, in turn, the proportion of young adults with positive anti-HAV has significantly decreased. This has led to the incidence of symptomatic acute hepatitis A increasing since the late 1990s. The incidence of serious complications including fulminant hepatic failure and acute kidney injury has also showed an increasing trend. Variation of the genotype of virus isolated from recent hepatitis A patients suggests an inflow of the hepatitis virus from other countri... Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3127040 Tue, 01 Dec 2009 00:00:00 +0100 3127040 http://www.medworm.com/index.php?rid=3127039&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20037263%26dopt%3DAbstract CONCLUSIONS: Entecavir induced excellent biochemical and virologic responses in naive CHB patients. EVR was an independent factor for predicting HBV PCR negativity and HBeAg loss. PMID: 20037263 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3127039 Tue, 01 Dec 2009 00:00:00 +0100 3127039 http://www.medworm.com/index.php?rid=3127038&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20037264%26dopt%3DAbstract CONCLUSIONS: All noninvasive serum markers evaluated in this study were useful for predicting significant or extensive liver fibrosis in chronic viral liver diseases. In particular, APRI was most useful for the prediction of significant fibrosis, and CDS was most useful for the prediction of extensive fibrosis. PMID: 20037264 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3127038 Tue, 01 Dec 2009 00:00:00 +0100 3127038 http://www.medworm.com/index.php?rid=3127037&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20037265%26dopt%3DAbstract CONCLUSIONS: Liver stiffness as measured by transient elastography is associated with the grade of necroinflammatory activity and the stage of fibrosis, irrespective of serum ALT levels. PMID: 20037265 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3127037 Tue, 01 Dec 2009 00:00:00 +0100 3127037 http://www.medworm.com/index.php?rid=3127036&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20037266%26dopt%3DAbstract CONCLUSIONS: TACE and RFA exhibited similar therapeutic effects in terms of recurrence and survival for patients with a single HCC smaller than 4 cm, if they could exhibited complete responses. PMID: 20037266 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3127036 Tue, 01 Dec 2009 00:00:00 +0100 3127036 http://www.medworm.com/index.php?rid=3127035&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20037267%26dopt%3DAbstract CONCLUSIONS: The up-regulated expression of FZD10 and CAMK2A suggests that the Wnt/Ca(2+) signaling pathway is active in hTERT HSCs and may participate in HSC activation and proliferation. PMID: 20037267 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3127035 Tue, 01 Dec 2009 00:00:00 +0100 3127035 http://www.medworm.com/index.php?rid=3127034&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20037268%26dopt%3DAbstract CONCLUSIONS: The 24-week plus additional split 24-week therapy following failure is a useful treatment strategy for patients with genotype 1 CHC. PMID: 20037268 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3127034 Tue, 01 Dec 2009 00:00:00 +0100 3127034 http://www.medworm.com/index.php?rid=3127033&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20037269%26dopt%3DAbstract We describe two cases of symptomatic toxic hepatitis that developed in middle-aged women after ingesting arrowroot juice. The clinical manifestations were nausea, vomiting, and jaundice. The diagnosis of toxic hepatitis was made using the Roussel Uclaf Causality Assessment Method score on the basis of the patient's history and laboratory data. After supportive care, the patients showed rapid improvements of clinical symptoms, laboratory findings, and liver stiffness. Clinicians should be aware that the consumption of arrowroot juice can cause toxic hepatitis. PMID: 20037269 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3127033 Tue, 01 Dec 2009 00:00:00 +0100 3127033 http://www.medworm.com/index.php?rid=3127032&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20037270%26dopt%3DAbstract We present a case of primary hepatic epithelioid hemangioendothelioma in a 65-year-old male patient with alcoholic liver cirrhosis. He was hospitalized due to epigastric pain and multiple liver masses on abdominal ultrasound. Dynamic liver CT imaging revealed multiple peripheral nodular enhanced mass lesions with delayed centripetal enhancement, and the adjacent collection of high-attenuation fluid along the liver capsule. Abdominal tapping revealed blood in the peritoneal cavity. Primary hepatic epithelioid hemangioendothelioma with spontaneous rupture was finally diagnosed based on a histopathologic examination revealing positive immunohistochemical staining for CD34. PMID: 20037270 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3127032 Tue, 01 Dec 2009 00:00:00 +0100 3127032 http://www.medworm.com/index.php?rid=3127031&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20037271%26dopt%3DAbstract We report herein a case of hepatotoxicity induced by Corydalis speciosa Max. A 37-year-old male complained of jaundice and mild abdominal discomfort. A thorough history was taken, and laboratory investigation, diagnostic imaging studies, and percutaneous liver biopsy sampling were conducted to determine the cause of liver injury. An accurate cause was not revealed. We administered supportive management for acute cholestatic hepatitis of unknown origin, after which his symptoms disappeared and serum aminotransferase levels decreased gradually to near normal levels. However, at 2 months after discharge, the symptoms and the elevation of aminotransferase levels recurred. At that time he told us that he had repeatedly but unintentionally eaten a herb called "Hwang-geun cho"(Corydalis speciosa ... Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3127031 Tue, 01 Dec 2009 00:00:00 +0100 3127031 http://www.medworm.com/index.php?rid=3127030&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20037272%26dopt%3DAbstract Authors: Jeen YM, Jin SY PMID: 20037272 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3127030 Tue, 01 Dec 2009 00:00:00 +0100 3127030 http://www.medworm.com/index.php?rid=3127029&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20037273%26dopt%3DAbstract Authors: Lee WJ PMID: 20037273 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3127029 Tue, 01 Dec 2009 00:00:00 +0100 3127029 http://www.medworm.com/index.php?rid=3127028&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20037274%26dopt%3DAbstract Authors: Hahn T PMID: 20037274 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=3127028 Tue, 01 Dec 2009 00:00:00 +0100 3127028 http://www.medworm.com/index.php?rid=2843181&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19783878%26dopt%3DAbstract Authors: Jin HS, Oh B PMID: 19783878 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2843181 Mon, 31 Aug 2009 23:00:00 +0100 2843181 http://www.medworm.com/index.php?rid=2843180&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19783879%26dopt%3DAbstract Authors: Song IH Hepatocellular carcinoma (HCC) is a major global health problem, which has a grave morbidity and mortality. Over the past few decades, no effective systemic therapeutic modalities have been established for patients with the unresectable HCC in advanced stage. Sorafenib is a small molecule that blocks cancer cell proliferation by targeting the intracellular signaling pathway at the level of Raf-1 and B-Raf serine-threonine kinases, and exerts an anti-angiogenic effect by targeting the vascular endothelial growth factor receptor-1, 2 and 3, and platelet-derived growth factor receptor-beta tyrosine kinases. Recently, two clinical successful applications, SHARP and Asia-Pacific trial, of multikinase inhibitor sorafenib represent a significant advance in the treatment of ad... Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2843180 Mon, 31 Aug 2009 23:00:00 +0100 2843180 http://www.medworm.com/index.php?rid=2843179&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19783880%26dopt%3DAbstract CONCLUSIONS: The arche haplotype of the ATP7B gene in Korean patients with WD may be 5-R778L-4 (D13S315.mutation.D13S316), and it might illustrate a founder effect. PMID: 19783880 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2843179 Mon, 31 Aug 2009 23:00:00 +0100 2843179 http://www.medworm.com/index.php?rid=2843178&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19783881%26dopt%3DAbstract CONCLUSIONS: Serum OPN levels were significantly higher in patients with advanced HCC. In addition, HCC patients with low pretreatment serum OPN levels and those for whom serum OPN declined following TACE exhibited better tumor responses and survived for longer. PMID: 19783881 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2843178 Mon, 31 Aug 2009 23:00:00 +0100 2843178 http://www.medworm.com/index.php?rid=2843177&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19783882%26dopt%3DAbstract CONCLUSION: A 48-week course of clevudine therapy was highly effective in patients with CHB. The risk of development of resistance to clevudine was increased in patients with previous exposure to lamivudine and cirrhosis. PMID: 19783882 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2843177 Mon, 31 Aug 2009 23:00:00 +0100 2843177 http://www.medworm.com/index.php?rid=2843176&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19783883%26dopt%3DAbstract CONCLUSIONS: Adherence to therapy is a key factor in achieving an SVR. Supportive strategies to improve adherence will increase overall SVR rates. PMID: 19783883 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2843176 Mon, 31 Aug 2009 23:00:00 +0100 2843176 http://www.medworm.com/index.php?rid=2843175&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19783884%26dopt%3DAbstract CONCLUSIONS: Both MELD and HVPG are independent prognostic factors of death within 3 and 12 months in patients with decompensated liver cirrhosis, and their accuracies are similar. However, HVPG has a limited role in the prediction of death in decompensated cirrhosis due to its invasiveness and limited use. PMID: 19783884 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2843175 Mon, 31 Aug 2009 23:00:00 +0100 2843175 http://www.medworm.com/index.php?rid=2843174&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19783885%26dopt%3DAbstract We report a rare case of rib metastasis from HCC treated by transcatheter arterial chemoembolization (TACE). A 55-year-old man with liver cirrhosis presented with right lower chest pain. The diagnosis was an HCC with a bone metastasis in the right eighth rib. Intra-arterial injections of doxorubicin mixed with Lipiodol and Gelfoam particles were instituted through the right eighth intercostal artery. Computed tomography and a Tc(99)-labeled scan performed 2 months after the third TACE revealed no viable HCC in the right eighth rib. PMID: 19783885 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2843174 Mon, 31 Aug 2009 23:00:00 +0100 2843174 http://www.medworm.com/index.php?rid=2843173&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19783886%26dopt%3DAbstract We report four cases of hepatitis A in which patients presented with fulminant hepatitis and acute renal failure and underwent liver transplantation. The following common features were observed in our cases: (1) occurrence in relatively old age (>/=39 years old), (2) association with acute renal failure, (3) presence of hepatomegaly, and (4) microscopic features of submassive hepatic necrosis. PMID: 19783886 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2843173 Mon, 31 Aug 2009 23:00:00 +0100 2843173 http://www.medworm.com/index.php?rid=2843172&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19783887%26dopt%3DAbstract We report a 60-year-old male patient who developed sudden-onset hearing loss during combination therapy with pegylated interferon alpha and ribavirin for chronic hepatitis C. This patient had been diagnosed with chronic hepatitis C (genotype Ib) and early-stage liver cirrhosis 3 years previously, and had been treated with conventional interferon-alpha and ribavirin for 12 months. However, 6 months from the end of the treatment course the patient relapsed and received combination retreatment with pegylated interferon alpha-2b and ribavirin. He developed sudden-onset right-side hearing loss and tinnitus 42 weeks after the start of this retreatment. Pure-tone audiometry revealed a right-side hearing loss of 60~90dB. The patient consequently immediately discontinued the pegylated interferon th... Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2843172 Mon, 31 Aug 2009 23:00:00 +0100 2843172 http://www.medworm.com/index.php?rid=2843171&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19783888%26dopt%3DAbstract Authors: Kim H, Park YN PMID: 19783888 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2843171 Mon, 31 Aug 2009 23:00:00 +0100 2843171 http://www.medworm.com/index.php?rid=2843170&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19783889%26dopt%3DAbstract Authors: Lee WJ PMID: 19783889 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2843170 Mon, 31 Aug 2009 23:00:00 +0100 2843170 http://www.medworm.com/index.php?rid=2843169&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19783890%26dopt%3DAbstract Authors: Kim JH PMID: 19783890 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2843169 Mon, 31 Aug 2009 23:00:00 +0100 2843169 http://www.medworm.com/index.php?rid=2843168&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19783891%26dopt%3DAbstract Authors: Hepatocellular carcinoma (HCC) is a major cancer in Korea, typically has a poor prognosis, and constitutes the majority of primary hepatic malignancies. It is the number one cause of death among people in their 50s in Korea. The five-year survival rate of liver cancer is poor; at 18.9%. Efforts to increase the survival rate through early diagnosis of HCC and optimal treatments are keenly needed. Western guideline for the management of HCC were developed, but these guidelines are somewhat unsuitable for Korean patients. Thus, the Korean Liver Cancer Study Group (KLCSG) and the National Cancer Center (NCC), Korea jointly produced the Clinical Practice Guidelines for HCC for the first time in Korea in 2003. Owing to medical advances over the following six years, diagnosis and t... Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2843168 Mon, 31 Aug 2009 23:00:00 +0100 2843168 http://www.medworm.com/index.php?rid=2843167&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19783892%26dopt%3DAbstract Authors: Cho JH, Yoon KH, Lee KE, Park do S, Lee YJ, Moon HB, Lee KR, Choi CS, Cho EY, Kim HC PMID: 19783892 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2843167 Mon, 31 Aug 2009 23:00:00 +0100 2843167 http://www.medworm.com/index.php?rid=2581438&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19581763%26dopt%3DAbstract Authors: Lee KS PMID: 19581763 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2581438 Sun, 31 May 2009 23:00:00 +0100 2581438 http://www.medworm.com/index.php?rid=2581437&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19581764%26dopt%3DAbstract Authors: Jeen YM, Jin SY Nonalcoholic steatohepatitis (NASH), one of the NAFLDs (nonalcoholic fatty liver diseases), is regarded as a hepatic manifestation of metabolic syndrome. NASH can progress to cirrhosis, and possibly to hepatic malignancy. Currently, liver biopsy is the only reliable method of assessing the presence or absence of NASH and the stage of fibrosis. The finding of steatosis with evidence of hepatocyte injury such as inflammation, ballooning, degeneration, and/or fibrosis, is generally essential for making a diagnosis of NASH. However, its diagnostic criteria have not yet been established. The pathologic findings of NASH and related diseases, and the grading system currently in use are reviewed herein. PMID: 19581764 [PubMed - in process] (Source: Korean J Hepatol... Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2581437 Sun, 31 May 2009 23:00:00 +0100 2581437 http://www.medworm.com/index.php?rid=2581436&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19581765%26dopt%3DAbstract CONCLUSIONS: Due to the adoptive immunity that was transferred from anti-HBs-positive donors, a seroconversion of HBsAg could occur in some HBsAg-positive recipients. HBsAg-positive donors had a lesser effect on the HBV serologic markers of recipients. However, a reactivation of HBV can occur following hematopoietic stem-cell transplantation in the cases of recipients or donors with a history of HBV, infection by an accompanying immune suppression. Therefore, prevention should be instigated. PMID: 19581765 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2581436 Sun, 31 May 2009 23:00:00 +0100 2581436 http://www.medworm.com/index.php?rid=2581435&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19581766%26dopt%3DAbstract CONCLUSIONS: The prevailing HBV genotype in Korea is C2; the other genotypes occur only rarely. Future studies should include confirmation of the detection of genotypes other than C. PMID: 19581766 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2581435 Sun, 31 May 2009 23:00:00 +0100 2581435 http://www.medworm.com/index.php?rid=2581434&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19581767%26dopt%3DAbstract CONCLUSIONS: The prognosis in patients with ruptured HCCs was poor with a 30-day mortality of 43.5%. The early deaths after the rupture of HCC were associated with elevated serum bilirubin levels, hepatic encephalopathy, and the massive or diffuse type of tumor morphology. PMID: 19581767 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2581434 Sun, 31 May 2009 23:00:00 +0100 2581434 http://www.medworm.com/index.php?rid=2581433&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19581768%26dopt%3DAbstract CONCLUSIONS: In patients with a protracted illness, hepatosplenomegaly and/or abnormal liver function tests, hepatic tuberculosis should be suspected, even in healthy young patients or patients with normal imaging findings. Patients with tuberculous abscess formation tend to respond poorly to antituberculosis therapy, and surgery could be considered in these patients. PMID: 19581768 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2581433 Sun, 31 May 2009 23:00:00 +0100 2581433 http://www.medworm.com/index.php?rid=2581432&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19581769%26dopt%3DAbstract CONCLUSIONS: Younger children (age <7 years old) have a higher chance of HBsAg clearance than older children after the treatment of HBeAg-positive chronic hepatitis B with lamivudine. PMID: 19581769 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2581432 Sun, 31 May 2009 23:00:00 +0100 2581432 http://www.medworm.com/index.php?rid=2581431&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19581770%26dopt%3DAbstract CONCLUSIONS: Clevudine is one of the recommended first-line medicines for the treatment of chronic hepatitis B, but it is not free from resistance, particularly in patients with a history of previous lamivudine treatment, but also in naive patients. Clevudine should be avoided in previously lamivudine-exposed patients. In addition, reelevation of serum AST and CPK levels is not a rare occurrence, and close observation and follow-up tests are essential. PMID: 19581770 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2581431 Sun, 31 May 2009 23:00:00 +0100 2581431 http://www.medworm.com/index.php?rid=2581430&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19581771%26dopt%3DAbstract We report herein a case of benign HHN mimicking hepatocellular carcinoma in a 32-year-old male alcoholic liver cirrhosis patient without viral hepatitis infection. PMID: 19581771 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2581430 Sun, 31 May 2009 23:00:00 +0100 2581430 http://www.medworm.com/index.php?rid=2581429&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19581772%26dopt%3DAbstract We report herein a case of hepatoid adenocarcinoma of the stomach with liver metastasis. Gastric carcinoma generally presents as adenocarcinoma and rarely shows a hepatoid pattern, which can produce alpha-fetoprotein (AFP). The stomach is one of the common sites at which hepatoid adenocarcinoma has been detected. A 75-year-old female patient was admitted to the hospital with a symptom of epigastric discomfort. Gastrofibroscopy revealed a large tumor occupying the greater curvature of the stomach body. The level of serum AFP was markedly increased. Abdominal computed tomography revealed multiple liver masses. Biopsy samples of the gastric lesion and liver masses finally confirmed her case as hepatoid adenocarcinoma in the stomach with liver metastasis. The AFP-producing gastric carcinoma ne... Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2581429 Sun, 31 May 2009 23:00:00 +0100 2581429 http://www.medworm.com/index.php?rid=2581428&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19581773%26dopt%3DAbstract Authors: Kang HM, Park MJ, Hwang JM, Kim JW, Jeong SH A 63-year-old male experienced sudden diplopia after 9 weeks of administration of pegylated interferon (IFN) alpha-2b and ribavirin for chronic hepatitis C (CHC). Ophthalmologic examinations showed ptosis on the right upper lid and restricted right eye movement without any other neurological signs. A brain imaging study and repetitive nerve stimulation test indicated no abnormality. The acetylcholine receptor antibody titer and response to acetylcholinesterase inhibitors were negative, and the results of thyroid function tests were normal. The patient's ophthalmological symptoms improved rapidly 3 weeks after discontinuation of pegylated IFN alpha-2b and ribavirin. The ocular myasthenia associated with combination therapy of pegylat... Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2581428 Sun, 31 May 2009 23:00:00 +0100 2581428 http://www.medworm.com/index.php?rid=2581427&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19581774%26dopt%3DAbstract Authors: Seok JY, Kim YB PMID: 19581774 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2581427 Sun, 31 May 2009 23:00:00 +0100 2581427 http://www.medworm.com/index.php?rid=2581426&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19581775%26dopt%3DAbstract Authors: Lee WJ PMID: 19581775 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2581426 Sun, 31 May 2009 23:00:00 +0100 2581426 http://www.medworm.com/index.php?rid=2581425&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19581776%26dopt%3DAbstract Authors: Heo J PMID: 19581776 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2581425 Sun, 31 May 2009 23:00:00 +0100 2581425 http://www.medworm.com/index.php?rid=2309369&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19346780%26dopt%3DAbstract Authors: Park YG PMID: 19346780 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2309369 Sun, 01 Mar 2009 05:00:00 +0100 2309369 http://www.medworm.com/index.php?rid=2309367&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19346781%26dopt%3DAbstract Authors: Kim YJ, Lee HS Hepatocellular carcinoma (HCC) is associated with hepatitis B virus (HBV) as an etiologic agent in 80% of cases, and is the major cause of death among HBV carriers. Family history of HCC is a known risk factor for the development of HCC among chronically HBV infected patients; therefore, genetic factors are likely to modify the risk of HCC. However, the genetic factors that determine progression to HCC remain mostly to be recovered. It is estimated that there are millions of single nucleotide polymorphisms (SNPs) within human genome and they are likely to explain much of the genetic diversity of individuals. In this review, the natural history of HBV infection and host genetic factors related to HCC, study design and target gene selection for the detection of SN... Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2309367 Sun, 01 Mar 2009 05:00:00 +0100 2309367 http://www.medworm.com/index.php?rid=2309365&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19346782%26dopt%3DAbstract CONCLUSIONS: Lentivirus-mediated delivery of shRNA against HBx can effectively suppress the replication of HBV and reduce HBV cccDNA in cell culture systems. PMID: 19346782 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2309365 Sun, 01 Mar 2009 05:00:00 +0100 2309365 http://www.medworm.com/index.php?rid=2309363&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19346783%26dopt%3DAbstract CONCLUSIONS: Antiviral treatment of CHB with LMV or ADV for up to 5 years using the alternative antiviral agent as rescue medication appears to be a cost-effective strategy for both HBeAg-positive and HBeAg-negative CHB patients in Korea. Economic evaluation of antiviral therapies should be studied further and updated, particularly for newer agents. PMID: 19346783 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2309363 Sun, 01 Mar 2009 05:00:00 +0100 2309363 http://www.medworm.com/index.php?rid=2309360&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19346784%26dopt%3DAbstract CONCLUSIONS: Transient elastography is a useful method for diagnosing cirrhosis in patients with alcoholic liver disease. PMID: 19346784 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2309360 Sun, 01 Mar 2009 05:00:00 +0100 2309360 http://www.medworm.com/index.php?rid=2309358&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19346785%26dopt%3DAbstract CONCLUSIONS: Our data suggest that the adefovir-monotherapy-induced virologic response is not durable in most patients with LAMV-R HBeAg-positive CHB, especially in those with a high pretreatment HBV DNA level. PMID: 19346785 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2309358 Sun, 01 Mar 2009 05:00:00 +0100 2309358 http://www.medworm.com/index.php?rid=2309356&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19346786%26dopt%3DAbstract CONCLUSIONS: The results of our study suggest that RBP4 is a serologic marker for disease severity in patients with CLD. It could also be useful as an early marker of CLD and of the relative success of antiviral therapy. PMID: 19346786 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2309356 Sun, 01 Mar 2009 05:00:00 +0100 2309356 http://www.medworm.com/index.php?rid=2309354&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19346787%26dopt%3DAbstract CONCLUSIONS: Reappearance of HCV RNA after earlier achievement of an SVR might appear more frequently than previously reported. Close follow-up of these patients is recommended and the implication of temporary viremia should be determined in the future. PMID: 19346787 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2309354 Sun, 01 Mar 2009 05:00:00 +0100 2309354 http://www.medworm.com/index.php?rid=2309352&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19346788%26dopt%3DAbstract We report here a case of HCC that directly invaded the gallbladder, and that resembled gallbladder carcinoma invading the liver. PMID: 19346788 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2309352 Sun, 01 Mar 2009 05:00:00 +0100 2309352 http://www.medworm.com/index.php?rid=2309350&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19346789%26dopt%3DAbstract We report a case of acute hepatitis A complicated by rhabdomyolysis during hospitalization. PMID: 19346789 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2309350 Sun, 01 Mar 2009 05:00:00 +0100 2309350 http://www.medworm.com/index.php?rid=2309348&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19346790%26dopt%3DAbstract We report here a case of advanced HCC with portal vein tumor thrombosis that was effectively treated with percutaneous ethanol injection (PEI), having previously enabled subsequent successive transarterial chemoembolization (TACE). A 60-year-old male patient was diagnosed with a huge HCC, based on computed tomography and angiographic findings. Despite two sessions of TACE, the tumor invaded the right portal vein. PEI was performed on the malignant portal vein thrombosis, and three sessions thereof reduced the extent of tumor thrombi in the portal vein. Successive TACEs were performed to treat the HCC in the hepatic parenchyma. The patient was still living 19 months after the first PEI with no evidence of tumor recurrence, and his liver function remained well preserved. PMID: 19346790 [... Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2309348 Sun, 01 Mar 2009 05:00:00 +0100 2309348 http://www.medworm.com/index.php?rid=2309346&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19346791%26dopt%3DAbstract Authors: Seok JY, Park YN PMID: 19346791 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2309346 Sun, 01 Mar 2009 05:00:00 +0100 2309346 http://www.medworm.com/index.php?rid=2309344&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19346792%26dopt%3DAbstract Authors: Lee WJ PMID: 19346792 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2309344 Sun, 01 Mar 2009 05:00:00 +0100 2309344 http://www.medworm.com/index.php?rid=2309342&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19346793%26dopt%3DAbstract Authors: Park NH PMID: 19346793 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2309342 Sun, 01 Mar 2009 05:00:00 +0100 2309342 http://www.medworm.com/index.php?rid=2309393&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19119239%26dopt%3DAbstract Authors: Lee YJ PMID: 19119239 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2309393 Mon, 01 Dec 2008 05:00:00 +0100 2309393 http://www.medworm.com/index.php?rid=2309391&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19119240%26dopt%3DAbstract Authors: Yim HJ Hepatitis B virus (HBV) is a partially double stranded DNA virus with genetic diversity represented by eight genotypes (A to H). Natural course and response to treatment could be affected by HBV genotypes. HBV shows high rates of turn over in the absence of proof-reading ability. As a result, large amounts of quasispecies are produced naturally or antiviral-associated. HBV consists of four open reading frames, namely preS/S gene, precore/core gene, polymerase gene, and X gene. Mutations on preS gene can result in undetectable HBsAg even in case that HBV is replicating. Surface gene mutation leads to decreased binding affinity to anti-HBs, which is associated with a vaccine escape mutant. Precore mutation abolishes HBeAg whereas mutations on basal core promoter gene down... Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2309391 Mon, 01 Dec 2008 05:00:00 +0100 2309391 http://www.medworm.com/index.php?rid=2309388&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19119242%26dopt%3DAbstract CONCLUSIONS: FHF due to hepatitis A has increased in recent years, and in our cohort the HEP grade was closely associated with spontaneous survival. PMID: 19119242 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2309388 Mon, 01 Dec 2008 05:00:00 +0100 2309388 http://www.medworm.com/index.php?rid=2309386&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19119243%26dopt%3DAbstract CONCLUSIONS: The main cause of acute toxic hepatitis in the current study was the use of herbal medicines. The severity of liver injury at the time of admission was a major factor significantly associated with the hospitalization and recovery periods. PMID: 19119243 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2309386 Mon, 01 Dec 2008 05:00:00 +0100 2309386 http://www.medworm.com/index.php?rid=2309383&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19119244%26dopt%3DAbstract CONCLUSIONS: We found no significant differences in therapeutic efficacies and adverse effects between the alpha-2a and -2b types of peginterferon as the initial treatment regimen in naive chronic hepatitis C patients. PMID: 19119244 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2309383 Mon, 01 Dec 2008 05:00:00 +0100 2309383 http://www.medworm.com/index.php?rid=2309381&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19119245%26dopt%3DAbstract CONCLUSIONS: Although ADV monotherapy is effective, it leads to a high rate of mutations of HBV DNA reverse transcriptase gene in patients with chronic HBV infections who have LMV-resistant HBV mutants. PMID: 19119245 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2309381 Mon, 01 Dec 2008 05:00:00 +0100 2309381 http://www.medworm.com/index.php?rid=2309379&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19119246%26dopt%3DAbstract Authors: Hur WH, Woo HY, Jeong SW, You CR, Bae SH, Choi JY, Yoon SK The wide use of lamivudine in chronic hepatitis B has produced a monotonic increase in patients with lamivudine resistance. Therefore, treating lamivudine resistance in chronic hepatitis B is a major concern in clinical practice for the treatment of hepatitis B virus (HBV). There is conflicting evidence on the outcome of pegylated interferon alpha (PEG-IFN alpha) therapy against lamivudine-resistant HBV, which is due to mutations in the YMDD motif. We experienced a patient with chronic hepatitis B who was successfully treated with PEG-IFN alpha-2a after the development of virologic and biochemical breakthrough during lamivudine therapy. Virologic breakthrough was associated with the emergence of YMDD mutants 48 months ... Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2309379 Mon, 01 Dec 2008 05:00:00 +0100 2309379 http://www.medworm.com/index.php?rid=2309377&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19119247%26dopt%3DAbstract We report the clinical course and antiviral response in a patient with FCH due to recurrent hepatitis C after cadaveric liver transplantation who was treated with pegylated interferon alpha-2a and ribavirin. PMID: 19119247 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2309377 Mon, 01 Dec 2008 05:00:00 +0100 2309377 http://www.medworm.com/index.php?rid=2309375&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19119248%26dopt%3DAbstract We report a case of a 64-year old woman who underwent hepatic resection due to epithelioid hemangioendothelioma in the right lobe that progressed to extrahepatic metastases of the bone, pleura, and peritoneum 22 months later. However, after resection there was no primary hepatic recurrence. PMID: 19119248 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2309375 Mon, 01 Dec 2008 05:00:00 +0100 2309375 http://www.medworm.com/index.php?rid=2309373&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19119249%26dopt%3DAbstract Authors: Jeen YM, Jin SY PMID: 19119249 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2309373 Mon, 01 Dec 2008 05:00:00 +0100 2309373 http://www.medworm.com/index.php?rid=2309371&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19119250%26dopt%3DAbstract Authors: Lee WJ PMID: 19119250 [PubMed - indexed for MEDLINE] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2309371 Mon, 01 Dec 2008 05:00:00 +0100 2309371 http://www.medworm.com/index.php?rid=2077424&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19119239%26dopt%3DAbstract Authors: Lee YJ PMID: 19119239 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2077424 Mon, 01 Dec 2008 05:00:00 +0100 2077424 http://www.medworm.com/index.php?rid=2077423&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19119240%26dopt%3DAbstract Authors: Yim HJ Hepatitis B virus (HBV) is a partially double stranded DNA virus with genetic diversity represented by eight genotypes (A to H). Natural course and response to treatment could be affected by HBV genotypes. HBV shows high rates of turn over in the absence of proof-reading ability. As a result, large amounts of quasispecies are produced naturally or antiviral-associated. HBV consists of four open reading frames, namely preS/S gene, precore/core gene, polymerase gene, and X gene. Mutations on preS gene can result in undetectable HBsAg even in case that HBV is replicating. Surface gene mutation leads to decreased binding affinity to anti-HBs, which is associated with a vaccine escape mutant. Precore mutation abolishes HBeAg whereas mutations on basal core promoter gene down... Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2077423 Mon, 01 Dec 2008 05:00:00 +0100 2077423 http://www.medworm.com/index.php?rid=2077422&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19119241%26dopt%3DAbstract CONCLUSIONS: Severe hepatic inflammation can affect the LS findings and thus, care is required when assessing fibrosis stage using LS measurement in patients with severe inflammation. PMID: 19119241 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2077422 Mon, 01 Dec 2008 05:00:00 +0100 2077422 http://www.medworm.com/index.php?rid=2077421&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19119242%26dopt%3DAbstract CONCLUSIONS: FHF due to hepatitis A has increased in recent years, and in our cohort the HEP grade was closely associated with spontaneous survival. PMID: 19119242 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2077421 Mon, 01 Dec 2008 05:00:00 +0100 2077421 http://www.medworm.com/index.php?rid=2077420&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19119243%26dopt%3DAbstract CONCLUSIONS: The main cause of acute toxic hepatitis in the current study was the use of herbal medicines. The severity of liver injury at the time of admission was a major factor significantly associated with the hospitalization and recovery periods. PMID: 19119243 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2077420 Mon, 01 Dec 2008 05:00:00 +0100 2077420 http://www.medworm.com/index.php?rid=2077419&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19119244%26dopt%3DAbstract CONCLUSIONS: We found no significant differences in therapeutic efficacies and adverse effects between the alpha-2a and -2b types of peginterferon as the initial treatment regimen in naive chronic hepatitis C patients. PMID: 19119244 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2077419 Mon, 01 Dec 2008 05:00:00 +0100 2077419 http://www.medworm.com/index.php?rid=2077418&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19119245%26dopt%3DAbstract CONCLUSIONS: Although ADV monotherapy is effective, it leads to a high rate of mutations of HBV DNA reverse transcriptase gene in patients with chronic HBV infections who have LMV-resistant HBV mutants. PMID: 19119245 [PubMed - in process] (Source: Korean J Hepatol) Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2077418 Mon, 01 Dec 2008 05:00:00 +0100 2077418 http://www.medworm.com/index.php?rid=2077417&cid=s_30410_17_f&fid=30410&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19119246%26dopt%3DAbstract Authors: Hur WH, Woo HY, Jeong SW, You CR, Bae SH, Choi JY, Yoon SK The wide use of lamivudine in chronic hepatitis B has produced a monotonic increase in patients with lamivudine resistance. Therefore, treating lamivudine resistance in chronic hepatitis B is a major concern in clinical practice for the treatment of hepatitis B virus (HBV). There is conflicting evidence on the outcome of pegylated interferon alpha (PEG-IFN alpha) therapy against lamivudine-resistant HBV, which is due to mutations in the YMDD motif. We experienced a patient with chronic hepatitis B who was successfully treated with PEG-IFN alpha-2a after the development of virologic and biochemical breakthrough during lamivudine therapy. Virologic breakthrough was associated with the emergence of YMDD mutants 48 months ... Korean J Hepatol journals http://www.medworm.com/rss/comments.php?id=2077417 Mon, 01 Dec 2008 05:00:00 +0100 2077417