MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Lasers in Medical Science' source. Thu, 09 Feb 2012 19:02:35 +0100 http://www.medworm.com/index.php?rid=5674095&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ffv451873hmn0n483%2F Abstract  Diabetes mellitus (DM) and chronic periodontitis are common chronic diseases in adults in the world population. DM has a strong influence on the oral cavity and represents a risk factor for gingivitis and periodontitis. Low-level laser therapy (LLLT) has proven effective in the reduction of inflammation and swelling. The aim of the present study was to evaluate the efficacy of LLLT in diabetic periodontitis through histological analysis. A total of 300 diabetics with chronic periodontal disease and teeth indicated for extraction were assigned into six equal groups. In the groups 1 and 4, indicated teeth were extracted before treatment, and in the rest of the groups upon completion of the entire treatment. All patients received oral hygiene instructions and full-mo... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5674095 Mon, 06 Feb 2012 19:33:44 +0100 5674095 http://www.medworm.com/index.php?rid=5664361&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp0992383075764lj%2F Abstract  The aim of this work was to investigate the correlation between scanning laser polarimetry with variable corneal compensation (GDx VCC) parameters and blue-on-yellow perimetry (B/YP) indices in ocular hypertension (OHT). One eye each of 52 patients with OHT (with a normal visual field, a normal optic nerve, and an untreated IOP > 21 mmHg) was chosen. All patients were examined with the Octopus 101 automated perimetry dG2 program using the dynamic/normal strategy (white-on-white perimetry, W/WP), with the dG2 program using the dynamic strategy/BY method (blue-on-yellow perimetry, B/YP), and with GDx VCC. Seven of the 52 OHT patients had both B/YP visual field loss and retinal nerve fiber layer (RNFL) defects with the GDx VCC measurements, and four patients ... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5664361 Fri, 03 Feb 2012 17:11:21 +0100 5664361 http://www.medworm.com/index.php?rid=5664362&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw267877027j22176%2F Abstract  Lasers are used extensively in ophthalmology for a variety of conditions, including many choroidal and retinal tumors. With technologic advances, current therapy attempts not only to maximize survival with globe-salvaging treatment, but also to preserve vision. Each neoplasm has different indications for primary and adjuvant therapy, as well as differing laser treatment protocols. Additionally, there are numerous laser applications available for use, including laser photocoagulation, transpupillary thermotherapy (TTT), and photodynamic therapy (PDT). The current review outlines the basic principles of laser treatment for intraocular tumors, focusing on the indications, treatment protocols, efficacy, and safety, while also presenting the latest advances in intraocu... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5664362 Thu, 02 Feb 2012 18:15:44 +0100 5664362 http://www.medworm.com/index.php?rid=5643989&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk0412k1uw3311600%2F Abstract  With good hemostatic ability, the end-firing continuous-wave diode laser at 980 nm was used to enucleate the prostate (DiLEP) for the treatment of benign prostatic obstruction (BPO). The study compared the patients’ demographics and surgical outcomes between DiLEP and transurethral resection of the prostate (TURP). Patients with significant BPO and a total prostatic weight of 40 g or more who had undergone DiLEP (n = 74) or TURP (n = 52) during the same period at our hospital were enrolled for analysis. DiLEP was performed by a single surgeon (Yang), and TURP by three surgeons (Yang, Hsieh and Chang). The 4-U incision technique was developed for DiLEP. The diode laser ensured bloodless incision followed by blunt dissection using the resectoscope... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5643989 Thu, 26 Jan 2012 16:44:13 +0100 5643989 http://www.medworm.com/index.php?rid=5643991&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh9t627p055734602%2F Abstract  The biofilms formed by opportunistic yeasts serve as a persistent reservoir of infection and impair the treatment of fungal diseases. The aim of this study was to evaluate photodynamic inactivation (PDI) of biofilms formed by Candida spp. and the emerging pathogens Trichosporon mucoides and Kodamaea ohmeri by a cationic nanoemulsion of zinc 2,9,16,23-tetrakis(phenylthio)-29H,31H-phthalocyanine (ZnPc). Biofilms formed by yeasts after 48 h in the bottom of 96-well microtiter plates were treated with the photosensitizer (ZnPc) and a GaAlAs laser (26.3 J cm–2). The biofilm cells were scraped off the well wall, homogenized, and seeded onto Sabouraud dextrose agar plates that were then incubated at 37°C for 48 h. Efficient PDI of biofilms was verifie... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5643991 Wed, 25 Jan 2012 18:11:34 +0100 5643991 http://www.medworm.com/index.php?rid=5643990&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fhr3041460kh730r7%2F Abstract  Beneficial medical laser ablation removes material efficiently with minimal collateral damage. A Mark-III free electron laser (FEL), at a wavelength of 6.45 μm has demonstrated minimal damage and high ablation yield in ocular and neural tissues. While this wavelength has shown promise for surgical applications, further advances are limited by the high overhead for FEL use. Alternative mid-infrared sources are needed for further development. We compared the FEL with a 5-μs pulse duration with a Q-switched ZGP-OPO with a 100-ns pulse duration at mid-infrared wavelengths. There were no differences in the ablation threshold of water and mouse dermis with these two sources in spite of the difference in their pulse structures. There was a significant difference i... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5643990 Wed, 25 Jan 2012 18:11:34 +0100 5643990 http://www.medworm.com/index.php?rid=5635669&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F05114634m53186k6%2F Abstract  The aim of the present study was to evaluate the influence of post surface treatment methods on the push-out bond strength of adhesively luted quartz fiber posts. Thirty freshly extracted and endodontically treated human incisor teeth were prepared for quartz fiber posts. The posts were submitted to three different surface treatments (n = 10), including no treatment, 50-µm aluminum-oxide (Al2O3) airborne-particle abrasion and Er:YAG laser (10 Hz, 150 mJ) irradiation. The posts were luted with resin cement. Each root was sectioned perpendicularly to its long axis to create specimens of 1-mm thickness. After the specimens were stored in distilled water at 37°C for 24 h, their push-out bond strength was tested using a universal testing machin... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5635669 Tue, 24 Jan 2012 18:14:12 +0100 5635669 http://www.medworm.com/index.php?rid=5635670&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn44n60x241001203%2F Abstract  The aim of this study was to quantitatively investigate the effects of extracorporeal shockwave therapy (ESWT) on the nanostructure and adhesion force of collagen fibrils in a rat model of collagenase-induced Achilles tendinitis (CIAT) using histology and atomic force microscopy. A total of 45 rats were divided into experimental groups of three rats each: a control group, 27 CIAT rats with nine time points, and 15 ESWT rats with five time points. Progressive changes in nanostructure including the fibrillary diameter and D-periodicity, and biomechanical properties including the fibrillary adhesion forces in each healing phase were investigated over a 5-week period after collagenase injection. On postoperative day 3, CIAT rats showed granulomatous tissue associ... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5635670 Tue, 24 Jan 2012 18:14:09 +0100 5635670 http://www.medworm.com/index.php?rid=5635671&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fpm8r29315854408t%2F Abstract  Photodynamic therapy (PDT) is a therapeutic technique mainly applied to the treatment of malignant and pre-malignant lesions, which induces cell death by the combined effect of a photosensitizer, irradiation in a proper wavelength, and molecular oxygen. One of the main limitations of PDT using 5-aminolevulinic acid (ALA) is the superficial volume of treatment, mainly due to the limited penetration of topical photosensitization. In this context, the present study investigates if a laser micromachining producing microchannels on the tissue surface could improve ALA penetration and result in an increase in the treatment depth. The laser micromachining under femtosecond regime was performed on the tissue surface of rat livers. Conventional PDT was applied and the indu... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5635671 Tue, 24 Jan 2012 07:17:34 +0100 5635671 http://www.medworm.com/index.php?rid=5617209&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl38354061n2h6125%2F This article addresses the management of hereditary ankyloglossia using the diode laser and conventional surgery in siblings. Content Type Journal ArticleCategory Original ArticlePages 1-6DOI 10.1007/s10103-011-1047-2Authors S. Elanchezhiyan, Department of Periodontia, KSR Institute of Dental Sciences & Research, KSR Kalvinagar, Tiruchengode, Tamil Nadu 637215, IndiaR. Renukadevi, Department of Periodontia, KSR Institute of Dental Sciences & Research, KSR Kalvinagar, Tiruchengode, Tamil Nadu 637215, IndiaK. Vennila, Department of Periodontia, JKK Nataraja Dental College, NH 47, Komarapalayam, Namakkal, 638183 India Journal Lasers in Medical ScienceOnline ISSN 1435-604XPrint ISSN 0268-8921 (Source: Lasers in Medical Science) Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5617209 Wed, 18 Jan 2012 06:59:05 +0100 5617209 http://www.medworm.com/index.php?rid=5617210&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fkq36600718647h26%2F Abstract  Topical glucocorticoid (GC) therapy has been successfully used in the treatment of several common cutaneous diseases in clinical practice for a long time, and skin atrophy is one of the most typical cutaneous side effects of this therapy. The aim of this study was to evaluate the potential of noninvasive fluorescence spectroscopy (FS) technique in the detection and classification of GC-induced skin atrophy. A total of 20 male Wistar rats were used in the experimental protocol under controlled environmental conditions and with free access to food. One group received topical application of clobetasol propionate 0.05% for 14 days to induce cutaneous atrophy (atrophic group) and the other (control) group received only vehicle application following the same protoc... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5617210 Tue, 17 Jan 2012 07:17:27 +0100 5617210 http://www.medworm.com/index.php?rid=5593423&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc676825nu2310643%2F Content Type Journal ArticleCategory Brief ReportPages 1-4DOI 10.1007/s10103-011-1044-5Authors Parastoo Davari, Center for Research and Training in Skin Diseases and Leprosy, Tehran University of Medical Sciences, 415 Taleghani Ave, Tehran, 14166 IranFarzam Gorouhi, Center for Research and Training in Skin Diseases and Leprosy, Tehran University of Medical Sciences, 415 Taleghani Ave, Tehran, 14166 IranPantea Hashemi, Center for Research and Training in Skin Diseases and Leprosy, Tehran University of Medical Sciences, 415 Taleghani Ave, Tehran, 14166 IranFereydoun Behnia, Center for Research and Training in Skin Diseases and Leprosy, Tehran University of Medical Sciences, 415 Taleghani Ave, Tehran, 14166 IranAfsaneh Ghassemi, Tehran University of Medical Sciences, 83 Mostaghimi Alley, ... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5593423 Sat, 07 Jan 2012 16:55:39 +0100 5593423 http://www.medworm.com/index.php?rid=5576878&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft04885459666g2u4%2F Content Type Journal ArticleCategory Brief ReportPages 1-3DOI 10.1007/s10103-011-1041-8Authors Merete Haedersdal, Department of Dermatology D42, Bispebjerg University Hospital, Bispebjerg Bakke 23, 2400 Copenhagen, NV, DenmarkKatrine Togsverd-Bo, Department of Dermatology D42, Bispebjerg University Hospital, Bispebjerg Bakke 23, 2400 Copenhagen, NV, DenmarkUwe Paasch, Department for Dermatology, Venerology and Allergology, University of Leipzig, Leipzig, Germany Journal Lasers in Medical ScienceOnline ISSN 1435-604XPrint ISSN 0268-8921 (Source: Lasers in Medical Science) Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5576878 Thu, 05 Jan 2012 17:06:09 +0100 5576878 http://www.medworm.com/index.php?rid=5576879&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj41m52t63kw22712%2F Abstract  The aim of this work is to analyze the effects of LED therapy at 940 nm or cold water immersion therapy (CWI) after an acute bout of exercise on markers of muscle damage and inflammation. Thirty-two male Wistar rats were allocated into four groups: animals kept at rest (control), exercised animals (E), exercised + CWI (CWI), and exercised + LED therapy (LED). The animals swam for 100 min, after which blood samples were collected for lactate analysis. Animals in the E group were returned to their cages without treatment, the CWI group was placed in cold water (10°C) for 10 min and the LED group received LED irradiation on both gastrocnemius muscles (4 J/cm2 each). After 24 h, the animals were killed and the soleus muscles were submitted to histological an... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5576879 Thu, 05 Jan 2012 17:06:08 +0100 5576879 http://www.medworm.com/index.php?rid=5569115&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Few262q50x3rp2217%2F The objective of this study was to evaluate the effect of LLLT and LED on the viability of random skin flaps in rats. Forty-eight rats were divided into four groups, and a random skin flap (10 × 4 cm) was performed in all animals. Group 1 was the sham group; group 2 was submitted to LLLT 660 nm, 0.14 J; group 3 with LED 630 nm, 2.49 J, and group 4 with LLLT 660 nm, with 2.49 J. Irradiation was applied after surgery and repeated on the four subsequent days. On the 7th postoperative day, the percentage of flap necrosis was calculated and skin samples were collected from the viable area and from the transition line of the flap to evaluate blood vessels and mast cells. The percentage of necrosis was significantly lower in groups 3 and 4 compared to... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5569115 Fri, 30 Dec 2011 07:10:10 +0100 5569115 http://www.medworm.com/index.php?rid=5556870&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl82h1834p1868516%2F This study was designed to determine the laser dose for the stimulation, zero-bioactivation, and inhibition of normal and neoplastic cells in vitro. The medical use of laser biomodulation has been occurring for decades in the area of tissue healing and inflammatory conditions. The potential to modulate the regeneration and differentiation of early cellular precursors by laser photons is a valuable endeavor searching for novel and efficient methods. A 35-mW HeNe (632.8-nm) laser and power density of 1.25 mW/cm2 was used to irradiate tissue culture dishes seeded with 400 cells/dish of normal cells (CHO, CCL-226, 3 T3, and HSF) and neoplastic cells (EMT-6 and RIF-1). All cell lines were cultured using DMEM supplemented with 10% and 5% FBS, 2 mM glutamine and 100 U pe... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5556870 Wed, 28 Dec 2011 16:49:55 +0100 5556870 http://www.medworm.com/index.php?rid=5556871&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb51u2062453t4571%2F Abstract  The aim of this study was to validate the safety and effectiveness of a new therapeutic procedure for the treatment of lower leg telangiectasia without clinical vein insufficiency. A group of 20 healthy women aged between 24 and 47 years (mean±sem 37.05 ± 1.47) with lower leg telangiectasia without clinical vein insufficiency, previously investigated by echo colour Doppler sonography, were recruited and were treated with neodymium:YAG laser (mean±sem 2.5 ± 0.11 sessions). Good or excellent results were obtained in 16 patients and the improvements were statistically significant (p < 0.01). Out of the 20 patients, 16 were satisfied with the procedure. We strongly support laser treatment of lower leg telangiectasia since it allows injection of ... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5556871 Wed, 28 Dec 2011 16:49:53 +0100 5556871 http://www.medworm.com/index.php?rid=5556872&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq127l0n2k0556026%2F Abstract  From the oncological point of view, discrimination between the normal healing process and a pathological condition following laser surgery of the larynx is important in the management of possible residual/recurrent disease. However, the wound-healing process following laser surgery of the larynx is not well understood, especially regarding the gross morphological changes over time. The aims of this study were to analyze the serial temporal changes in the laryngeal endoscopic findings following laser cordectomy and to define the process involved in stabilization of the laryngeal mucosa. The study group comprised 46 consecutive patients with early glottic cancer undergoing laser cordectomy using the CO2 laser. All outpatient clinic endoscopic examinations were docume... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5556872 Tue, 27 Dec 2011 17:03:35 +0100 5556872 http://www.medworm.com/index.php?rid=5542367&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa628306n3272r013%2F Abstract  Many dental bleaching techniques are now available, several of them using a laser source. However, the literature on the exact role of coherent light in the biochemical reaction of the whitening process is very discordant. The aims of this in vitro study were: (1) to compare two different laser sources, a KTP laser with a wavelength of 532 nm and a diode laser with a wavelength of 808 nm, during dental bleaching, and (2) to investigate the relationships among changes in gel temperature, tooth shade and hydrogen peroxide (HP) concentration during laser irradiation. Altogether, 116 bovine teeth were bleached using a 30% HP gel, some of them with gel only and others with gel plus one of the two lasers (532 or 808 nm) at two different powers (2 and 4&nb... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5542367 Fri, 23 Dec 2011 16:52:25 +0100 5542367 http://www.medworm.com/index.php?rid=5542368&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb3x8367271434204%2F Abstract  There has recently been constant effort to evaluate therapies that may have a positive effect on bone regeneration. However, there are few studies in the literature on the effects of low-level laser therapy (LLLT) involving tissues treated with anabolic steroids. The present study evaluated the effects of LLLT (AsGaAl 780 nm, 3 J/cm2, 10 mW, beam spot of 0.04 cm2, total energy 0.12 J) on the proliferation, adhesion, and differentiation of osteoblasts cultured in the presence of nandrolone decanoate (ND). The MTT method was employed to evaluate cell proliferation and adhesion. Cell differentiation was evaluated by measuring alkaline phosphatase activity. There was a significant decrease in cell proliferation in the irradiated group treated w... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5542368 Wed, 21 Dec 2011 20:07:00 +0100 5542368 http://www.medworm.com/index.php?rid=5512542&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F950353471438t774%2F Abstract  This work carried out a histological analysis on bone defects grafted (MTA) treated or not with LED, BMPs, and membrane (GBR). Benefits of their isolated or combined usage on bone repair were reported, but not their association. Ninety rats were divided into ten groups and each subdivided into three. Defects on G II and I were filled with the blood clot. G II was further LED irradiated. G III and IV were filled with MTA; G IV was further LED irradiated. In G V and VI, the defects were filled with MTA and covered with a membrane (GBR). G VI was further LED irradiated. In G VII and VIII, BMPs were added to the MTA and group VIII was further LED irradiated. In G IX and X, the MTA + BMP graft was covered with a membrane (GBR). G X was further LED irradiated. ... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5512542 Wed, 14 Dec 2011 16:31:11 +0100 5512542 http://www.medworm.com/index.php?rid=5512543&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fjvr54u4734546572%2F In this study, a novel and less-traumatic method was tested. Tissue shrinkage effect of the CO2 laser was used to create cicatricial changes to treat involutional entropion in five patients. Resurfacing was accomplished with the Ultra Pulse CO2 (carbon dioxide) laser (model UP 5005, Coherent Medical Group, Santa Clara, CA) by the help of computerized pattern generator (CPG) scanning device. The first pass was performed to the entire lower lid and periorbital area, sparing the subciliary region, using 200 mJ of energy. The second pass used the same energy level, but this time resurfacing was extended as close as the lash line. All four of the five patients available for follow-up clinical evaluation (interval between 5 and 21 months) had surgical success with no recurrence of... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5512543 Tue, 13 Dec 2011 17:05:38 +0100 5512543 http://www.medworm.com/index.php?rid=5492760&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F66736u76l16q5547%2F This study examined the photothermal properties and cancer cell-killing ability of oxidized pSi (pSiO). The temperature measurement and in vitro cell tests including the annexin V-fluorescein isothiocyanate (FITC) apoptosis assay tests, MTT assay tests, and Trypan blue cell death assay tests were performed to compare the photothermal properties and the cytotoxic effect of pSiO with those of pSi in combination with an 808-nm NIR laser. pSiO showed lower photothermal properties and a lower cell-death rate than bare pSi. On the other hand, the pSiO treatment used in combination with an NIR laser treatment showed a cytotoxic effect high enough to kill a considerable portion of the cancer cells. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s10103-011-1032... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5492760 Wed, 07 Dec 2011 10:52:18 +0100 5492760 http://www.medworm.com/index.php?rid=5483467&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp1360w5w4n648233%2F Abstract  This work investigated the effect of gallium arsenide (GaAs) irradiation (power: 5 mW; intensity: 77.14 mW/cm2, spot: 0.07 cm2) on regenerating skeletal muscles damaged by crotoxin (CTX). Male C57Bl6 mice were divided into six groups (n = 5 each): control, treated only with laser at doses of 1.5 J or 3 J, CTX-injured and, CTX-injured and treated with laser at doses of 1.5 J or 3 J. The injured groups received a CTX injection into the tibialis anterior (TA) muscle. After 3 days, TA muscles were submitted to GaAs irradiation at doses of 1.5 or 3 J (once a day, during 5 days) and were killed on the eighth day. Muscle histological sections were stained with hematoxylin and eosin (H&E) in order to determine the myofibe... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5483467 Mon, 05 Dec 2011 17:43:52 +0100 5483467 http://www.medworm.com/index.php?rid=5483468&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh71t9586qu01m6pj%2F Abstract  Cochlear hair cells are the sensory receptors of the auditory system. It is well established that antibiotic drugs such as gentamicin can damage hair cells and cause hearing loss. Rescuing hair cells after ototoxic injury is an important issue in hearing recovery. Although many studies have indicated a positive effect of low-level laser therapy (LLLT) on neural cell survival, there has been no study on the effects of LLLT on cochlear hair cells. Therefore, the aim of this study was to elucidate the effects of LLLT on hair cell survival following gentamicin exposure in organotypic cultures of the cochlea of rats. The cochlea cultures were then divided into a control group (n = 8), a laser-only group (n = 8), a gentamicin-only group (n = 8) and a gentamic... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5483468 Sat, 03 Dec 2011 16:49:59 +0100 5483468 http://www.medworm.com/index.php?rid=5473770&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd03862k8048kw749%2F Abstract  Retinal development involves a complex coordination of events that may be affected by premature delivery, leading to retinopathy of prematurity (ROP), a potential blinding childhood disease. The avascular retina drives further disease progression, with laser ablation reducing unfavorable anatomic outcomes as well as maintaining visual acuity. Trials have stressed the importance of early identification and treatment of threshold and high-risk prethreshold disease to improve outcomes. Retinal ablation with laser photocoagulation should involve entire treatment of avascular retina with a confluent laser spot density, avoiding skip lesions. The current review highlights the use of laser photocoagulation in the treatment of ROP. Content Type Journal ArticleCategory... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5473770 Thu, 01 Dec 2011 19:20:51 +0100 5473770 http://www.medworm.com/index.php?rid=5465334&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe577335270567166%2F The objective of this study was to investigate the effects of sandblasting and different types of laser irradiation on the interfacial bond between titanium and resin cement through shear testing. A total of 60 samples (10 mm in length and 12 mm in diameter) were cut from titanium rods. The samples were divided into four equal groups according to the surface treatment: control, sandblasted, Nd:YAG laser-irradiated, and Er:YAG laser-irradiated. After surface treatment, the implant restorative cements were applied to the titanium samples which were stored in distilled water at 37°C for 24 h. The samples were then subjected to shear bond strength testing using a universal testing machine with a crosshead speed of 1 mm/min. The data were analysed with the Kruskal-Wal... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5465334 Mon, 28 Nov 2011 16:50:54 +0100 5465334 http://www.medworm.com/index.php?rid=5454214&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj1697g3635911244%2F Abstract  Acneiform rash associated with epidermal growth factor receptor inhibitors frequently presents facial manifestations. The treatment modality for such lesions still needs to be elucidated. The aim of this original report was to evaluate the effectiveness of high-level laser therapy in reducing the severity of facial acneiform rash induced by cetuximab, an epidermal growth factor receptor inhibitors. Four patients with metastatic colorectal cancer and two patients with head and neck cancer showing cetuximab-induced facial rash were treated by high-level laser therapy in two 8-min-long consecutive sessions/day over a 4-day treatment. Patients wore protective glasses to prevent eye damage related to laser light. Subsequently, patients were seen once a week for up to 2... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5454214 Fri, 25 Nov 2011 17:59:52 +0100 5454214 http://www.medworm.com/index.php?rid=5454213&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F30436v167h27q770%2F Abstract  The aim of this study was to evaluate the influence of the LED curing unit and selective enamel etching on dentin microtensile bond strength (μTBS) for self-etch adhesives in class I composite restorations. On 96 human molars, box-shaped class I cavities were made maintaining enamel margins. Self-etch adhesives (Clearfil SE – CSE and Clearfil S3 – S3) were used to bond a microhybrid composite. Before adhesive application, half of the teeth were enamel acid-etched and the other half was not. Adhesives and composites were cured with the following light curing units (LCUs): one polywave (UltraLume 5 - UL) and two single-peak (FlashLite 1401 - FL and Radii Cal - RD) LEDs. The specimens were then submitted to thermomechanical aging and longitudinally sectioned to o... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5454213 Fri, 25 Nov 2011 17:59:52 +0100 5454213 http://www.medworm.com/index.php?rid=5454215&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F437hu76141621161%2F In conclusion, the moisture conditions do not influence significantly the performance of the LFpen, but the presence of plaque can affect its performance in detecting occlusal caries lesions in primary teeth. Content Type Journal ArticleCategory Original ArticlePages 1-6DOI 10.1007/s10103-011-1025-8Authors Daniela G. Bittar, Department of Pediatric Dentistry, School of Dentistry, University of São Paulo, Av. Lineu Prestes 2227, São Paulo, BrazilThaís Gimenez, Department of Pediatric Dentistry, School of Dentistry, University of São Paulo, Av. Lineu Prestes 2227, São Paulo, BrazilCaroline C. Morais, Department of Pediatric Dentistry, School of Dentistry, University of São Paulo, Av. Lineu Prestes 2227, São Paulo, BrazilMonique S. De Benedetto, Department of Pediatric Dentist... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5454215 Thu, 24 Nov 2011 17:53:10 +0100 5454215 http://www.medworm.com/index.php?rid=5454216&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn107185074277435%2F Abstract  The success of endodontic treatment depends on the complete elimination of microorganisms from the root canal system, thus the search for new procedures to eliminate them is justified. The aim of this study was to assess bacterial reduction after intracanal irradiation with the Er:YAG laser. The canals of 70 extracted human maxillary canines were prepared up to file #40 using 1% NaOCl, irrigated with 17% EDTA, and then washed with physiological solution activated by ultrasound. The roots were sterilized by autoclaving, inoculated with 10 μl of a suspension containing 1.5 × 108 CFU/ml of Enterococcus faecalis ATCC 29212 and incubated at 37°C for 72 h. The canals were irradiated with the Er:YAG laser using two energy settings: 60 mJ and 15 ... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5454216 Tue, 22 Nov 2011 18:01:44 +0100 5454216 http://www.medworm.com/index.php?rid=5447794&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl2662863n6675650%2F The objective of this work was to compare the effects of antimicrobial photodynamic therapy (PDT), diode soft laser therapy (DSL), and thorough deep scaling and root planing (SRP) for treatment of residual pockets. Thirty-two subjects with a history of non-surgical treatment for chronic periodontitis were included. Residual pockets >4 mm and bleeding upon probing were debrided with an ultrasonic device and then subjected to either PDT, DSL, or SRP. Pocket probing depth (PPD), bleeding on probing (BOP), and gingival recession were monitored over 6 months. Counts of four microorganisms were determined by direct hybridization with RNA probes. PPD decreased from 5.6 ± 1.0 to 3.8 ± 1.1 in 6 months (p < 0.001), and BOP decreased from 100% to 52% (p <�... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5447794 Mon, 21 Nov 2011 18:08:57 +0100 5447794 http://www.medworm.com/index.php?rid=5437426&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F42805083275v8vl2%2F Abstract  Low-level laser irradiation (LLLI) and recombinant human bone morphogenetic protein type 2 (rhBMP-2) have been used to stimulate bone formation. LLLI stimulates proliferation of osteoblast precursor cells and cell differentiation and rhBMP-2 recruits osteoprogenitor cells to the bone healing area. This in vivo study evaluated the effects of LLLI and rhBMP-2 on the bone healing process in rats. Critical bone defects were created in the parietal bone in 42 animals, and the animals were divided into six treatment groups: (1) laser, (2) 7 μg of rhBMP-2, (3) laser and 7 μg of rhBMP-2, (4) 7 μg of rhBMP-2/monoolein gel, (5) laser and 7 μg rhBMP-2/monoolein gel, and (6) critical bone defect controls. A gallium-aluminum-arsenide diode laser was used... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5437426 Fri, 18 Nov 2011 06:59:01 +0100 5437426 http://www.medworm.com/index.php?rid=5428256&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn887477345263534%2F Content Type Journal ArticleCategory Brief ReportPages 1-7DOI 10.1007/s10103-011-1019-6Authors Carlos de Paula Eduardo, Special Laboratory of Lasers in Dentistry – LELO, Department of Restorative Dentistry, Faculdade de Odontologia da Universidade de São Paulo, São Paulo, BrazilLetícia Mello Bezinelli, Hematology and Bone Marrow Transplantation, Hospital Israelita Albert Einstein – HIAE, São Paulo, BrazilFernanda de Paula Eduardo, Hematology and Bone Marrow Transplantation, Hospital Israelita Albert Einstein – HIAE, São Paulo, BrazilRoberta Marques da Graça Lopes, Hematology and Bone Marrow Transplantation, Hospital Israelita Albert Einstein – HIAE, São Paulo, BrazilKaren Müller Ramalho, Special Laboratory of Lasers in Dentistry – LELO, Department of Restorative Denti... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5428256 Tue, 15 Nov 2011 16:48:47 +0100 5428256 http://www.medworm.com/index.php?rid=5417896&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe567164r37q83378%2F Abstract  Many studies have shown the positive effects of low-level laser therapy in the treatment of bone disease. However, laser radiation is scattered in the skin surface which reduces the initial photon density for tissue penetration and consequently the therapeutic efficacy. We developed a minimally invasive laser needle system (MILNS) to avoid laser scattering in tissue and investigated its stimulatory effects in the cortical bone of osteoporotic mice. The MILNS was designed to stimulate cortical bone directly by employing fine hollow needles to guide 100 μm optical fibers. The study animals comprised 12 mice which were subjected to sciatic denervation of the right hind limb and were randomly divided into two groups, a sham group and a laser group which were tre... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5417896 Mon, 14 Nov 2011 16:54:51 +0100 5417896 http://www.medworm.com/index.php?rid=5417897&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fht1m17u2861x3685%2F Abstract  The aim of this in-vitro study was to compare the performance of laser-based (DIAGNOdent, KaVo, Biberach, Germany) and LED-based (Midwest Caries I.D., DENTSPLY Professional, New York, USA) caries detectors in the detection of occlusal caries in permanent molars. The study consisted of 129 visually sound or non-cavitated pits or fissures in 82 extracted permanent human molar teeth. Two trained examiners used the laser-based and LED-based caries detectors to examine the fissures for caries. The teeth were then sectioned at the surfaces suspected of containing occlusal caries and histologically evaluated using stereomicroscopy as a gold standard. Inter-examiner reliability of the caries detector examination was assessed using Cohen’s Kappa statistics. The sensitivi... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5417897 Sat, 12 Nov 2011 06:48:35 +0100 5417897 http://www.medworm.com/index.php?rid=5404857&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl237734770t16284%2F Abstract  Laser use is effective in the debonding of ceramic brackets. However, a standardization of the laser debonding techniques used has not yet been implemented. The purpose of this study was to evaluate the effect of the time lag elapsed between lasing and shearing on debonding of ceramic brackets. One hundred polycrystalline ceramic brackets were placed on human premolar teeth, which were randomly divided into five groups of 20. One group was assigned as the control. The Er-YAG laser was applied on each bracket in four experimental groups at 5 W for 6 s with the scanning method. Debonding was performed 1 s, 18 s, 30 s, or 60 s after laser exposure. Shear bond strengths and adhesive remnant index scores were measured. Statistically significant ... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5404857 Thu, 10 Nov 2011 16:51:14 +0100 5404857 http://www.medworm.com/index.php?rid=5404858&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj421m04g7q647v65%2F This study demonstrates the higher ablation efficiency and resistance to degradation of the LTW fiber as compared to the STW and SF fibers. The STW fiber has a similar ablation rate of the SF fiber but resists degradation better. Content Type Journal ArticleCategory Original ArticlePages 1-5DOI 10.1007/s10103-011-1017-8Authors Hassan Shaker, Urology Department, Ain Shams University, Cairo, EgyptAlsayed Alokda, Department of Occupational Health and Environment, Ain Shams University, Cairo, EgyptHisham Mahmoud, National Institute of Laser Sciences, Cairo University, Cairo, Egypt Journal Lasers in Medical ScienceOnline ISSN 1435-604XPrint ISSN 0268-8921 (Source: Lasers in Medical Science) Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5404858 Wed, 09 Nov 2011 17:55:25 +0100 5404858 http://www.medworm.com/index.php?rid=5404859&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj3r531m885047818%2F Abstract  The aim of this study is to quantitatively investigate the short-term effects of RF tissue-tightening treatment in in vivo rabbit dermal collagen fibrils. These effects were measured at different energy levels and at varying pass procedures on the nanostructural response level using histology and AFM analysis. Each rabbit was divided into one of seven experimental groups, which included the following: control group, and six RF group according to RF energy (20 W and 40 W) and three RF pass procedures. The progressive changes in the diameter and D-periodicity of rabbit dermal collagen fibrils were investigated in detail over a 7-day post-treatment period. The dermal tissues treated with the RF tissue-tightening device showed more prominent inflammatory res... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5404859 Tue, 08 Nov 2011 19:15:04 +0100 5404859 http://www.medworm.com/index.php?rid=5397020&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F26484537486x4002%2F The objective of this study was to evaluate the possible additive effects of low-power laser treatment in combination with conventional physiotherapy endeavors in these patients. A total of 50 patients who were referred to the Physical Medicine and Rehabilitation Clinic with shoulder pain and rotator cuff disorders were selected. Pain severity measured with visual analogue scale (VAS), abduction, and external rotation range of motion in shoulder joint was measured by goniometry, and evaluation of daily functional abilities of patients was measured by shoulder disability questionnaire. Twenty-five of the above patients were randomly assigned into the control group and received only routine physiotherapy. The other 25 patients were assigned into the experimental group and received conv... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5397020 Thu, 03 Nov 2011 16:55:09 +0100 5397020 http://www.medworm.com/index.php?rid=5375848&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm7226r7w46g94q11%2F Abstract  Human immunodeficiency virus (HIV) particles that remain in the blood of patients are frequently ignored as targets for AIDS treatment. We therefore investigated the use of photodynamic therapy (PDT) with hematoporphyrin monomethyl ether (HMME) as a means of inactivating cell-free HIV in vitro. Virus particles including HIV-1IIIB, resistant HIV-1 variants, HIV-1 clinical variants, and HIV-2 variants were incubated with HMME for 40 min, followed by irradiation with a 630-nm semiconductor laser at an energy density of 0.3 J/cm2. The antiviral effects were evaluated by counting syncytium formation or measuring p24 antigen expression levels in supernatants by enzyme-linked immunosorbent assay. The relationships between photoinactivation and HMME concentrations... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5375848 Wed, 02 Nov 2011 05:49:51 +0100 5375848 http://www.medworm.com/index.php?rid=5375849&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv1t40235xw6kp742%2F Abstract  The application of low-power laser irradiation (LLI) affects the cell cycle and cell proliferation in various kinds of cells. LLI at a wavelength of 808 nm and a power of 30 mW has been found to significantly decrease the proliferation rate of cells of the human-derived glioblastoma cell line A-172. To determine if this effect of LLI is specific to 808-nm LLI, the present study was designed to reveal the effects of 405-nm LLI under the same experimental conditions. A-172 glioblastoma cells were cultured in 96-well plates according to the conventional protocol. Two different schedules of 405-nm LLI (27 mW) were tested: longer periods of 20, 40 and 60 min and shorter periods of 1, 2, 3, 5, 10 and 15 min. Cells on a digital image displayed on ... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5375849 Mon, 31 Oct 2011 16:58:23 +0100 5375849 http://www.medworm.com/index.php?rid=5375850&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl05773p15l8vu925%2F This study may be relevant when determining the overall satisfaction of patients with this new technology. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s10103-011-1012-0Authors Carlo Fornaini, TELEO Laboratory, Faculty of Dentistry, University of Nice-Sophia Antipolis (France), 24, Avenue des Diables Bleus, 06357 Nice Cedex, FranceDavid Riceputi, TELEO Laboratory, Faculty of Dentistry, University of Nice-Sophia Antipolis (France), 24, Avenue des Diables Bleus, 06357 Nice Cedex, FranceLaurence Lupi-Pegurier, TELEO Laboratory, Faculty of Dentistry, University of Nice-Sophia Antipolis (France), 24, Avenue des Diables Bleus, 06357 Nice Cedex, FranceJean Paul Rocca, TELEO Laboratory, Faculty of Dentistry, University of Nice-Sophia Antipolis (France), 24, Aven... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5375850 Mon, 31 Oct 2011 16:58:22 +0100 5375850 http://www.medworm.com/index.php?rid=5375851&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk1722711863w4967%2F Content Type Journal ArticleCategory Brief ReportPages 1-4DOI 10.1007/s10103-011-1015-xAuthors Guillaume Mahé, Laboratory of Vascular Investigations, University Hospital of Angers, 4 rue Larrey, 49933 Angers Cedex 9, FranceSylvain Durand, Laboratory “Motricité, Interactions, Performance” EA 4334, Faculty of Sport Sciences, University of Le Mans, Le Mans, FranceAnne Humeau, Laboratoire d’Ingénierie des Systèmes Automatisés (LISA), Université d’Angers, 62 Avenue Notre Dame du Lac, 49000 Angers, FranceGeorges Leftheriotis, Laboratory of Vascular Investigations, University Hospital of Angers, 4 rue Larrey, 49933 Angers Cedex 9, FrancePascal Rousseau, Laboratory of Vascular Investigations, University Hospital of Angers, 4 rue Larrey, 49933 Angers Cedex 9, FrancePierre Abraham,... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5375851 Mon, 31 Oct 2011 16:58:21 +0100 5375851 http://www.medworm.com/index.php?rid=5375852&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj7qu45p04v6125gn%2F Abstract  The aim of this study was to investigate the effect of different working modes (pulsed and micropulsed) and power settings of a standardized 980-nm diode laser on collateral thermal soft-tissue damage. A total of 108 bovine liver samples were cut with a diode laser at various settings in pulsed and micropulsed mode and histologically assessed to determine the area and depth of carbonization, necrosis and reversible tissue damage, as well as incision depth and width. Incision depth and width and the area and depth of carbonization, necrosis and reversible damage were correlated strongly with cutting speed. The area and depth of reversible damage were correlated with average power. The micropulsed mode produced a smaller zone of carbonization and necrosis and a smal... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5375852 Fri, 28 Oct 2011 05:48:40 +0100 5375852 http://www.medworm.com/index.php?rid=5343672&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq25m2vn15970082w%2F Abstract  We studied peaks of calcium hydroxyapatite (CHA) and protein and lipid CH groups in defects grafted with mineral trioxide aggregate (MTA) treated or not with LED irradiation, bone morphogenetic proteins and guided bone regeneration. A total of 90 rats were divided into ten groups each of which was subdivided into three subgroups (evaluated at 15, 21 and 30 days after surgery). Defects were irradiated with LED light (wavelength 850 ± 10 nm) at 48-h intervals for 15 days. Raman readings were taken at the surface of the defects. There were no statistically significant differences in the CHA peaks among the nonirradiated defects at any of the experimental time-points. On the other hand, there were significant differences between the defects filled ... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5343672 Thu, 20 Oct 2011 15:52:46 +0100 5343672 http://www.medworm.com/index.php?rid=5343671&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F174g836322047766%2F Abstract  Skin flaps are still a matter of concern among surgeons, as failures can occur leading to flap necrosis. However, low-level laser irradiation has been reported as an effective tool to improve the viability of ischemic flaps, yet its mechanisms of action remain unclear. We investigated the effect of low-level laser irradiation on the viability of random skin flaps in rats and determined COX-2 expression in the flap pedicle. The study animals comprised 24 EPM-1 Wistar rats which were randomly allocated into three equal groups. A cranially based dorsal random skin flap measuring 10 × 4 cm was created in all the animals. In one group, laser irradiation was simulated (sham group), and in the other two groups the animals were irradiated at 12 points with 0.29&... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5343671 Thu, 20 Oct 2011 15:52:46 +0100 5343671 http://www.medworm.com/index.php?rid=5343673&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp757m137xjp1m541%2F In conclusion, nonconherent red light can promote proliferation but cannot induce osteogenic differentiation of MSCs in normal media, while it enhances osteogenic differentiation and decreases proliferation of MSCs in media with osteogenic supplements. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s10103-011-1005-zAuthors Fei Peng, Department of Orthopedics, Renmin Hospital of Wuhan University, Wuhan, 430060 ChinaHua Wu, Department of Orthopedics, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 1095 Jiefang Street, Wuhan, 430030 ChinaYadong Zheng, Department of Orthopedics, Minzu Hospital of Guangxi Zhuang Autonomous Region, Nanning, 530001 ChinaXiqiang Xu, Department of Orthopedics, Tongji Hospital, Tongji Medica... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5343673 Thu, 20 Oct 2011 15:52:44 +0100 5343673 http://www.medworm.com/index.php?rid=5343674&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp167850732p23630%2F Abstract  Ureteroscopic laser lithotripsy is a commonly used technique to treat ureteral calculi.The type of energy source used is one of the main influences of retrograd calculi propulsion. Using a momentum pendulum under-water set-up the induced momentum and the initial velocity were investigated. Pulsed laser light from three different clinically available laser systems, including a Ho:YAG laser, a frequency-doubled double-pulse (second harmonic generation, SHG) Nd:YAG laser and a flash-lamp pumped dye (FLPD) laser, were transmitted via flexible fibres of different core diameter to the front of the pendulum sinker. Single pulses at variable pulse energy, according to the clinical laser parameter settings, were applied to the target sinker, thus causing a repulsion-induce... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5343674 Wed, 19 Oct 2011 15:50:38 +0100 5343674 http://www.medworm.com/index.php?rid=5343675&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh90l787154489536%2F Abstract  The aim of this study is to analyze the effects of low-level laser therapy (LLLT) on the regeneration of the sciatic nerve in rats following a complete nerve resection. Male Wistar rats were divided into a control injury group, injury groups irradiated with a 660-nm laser at 10 or 50 J/cm2, and injury groups irradiated with an 808-nm laser at 10 or 50 J/cm2. Treatment began 24 h following nerve resection and continued for 15 days. Using the sciatic functional index (SFI), we show that the injured animals treated with 660 nm at 10 and 50 J/cm2 had better SFI values compared with the control injury and the 808-nm groups. Animals irradiated with the 808-nm laser at 50 J/cm2 show higher values for fiber density than do control animals.... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5343675 Tue, 18 Oct 2011 15:57:36 +0100 5343675 http://www.medworm.com/index.php?rid=5330947&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa60377177l73667k%2F Conclusions: low-level diode laser treatment increased the MG63 cell proliferative ability and decreased the expression of inflammatory mediators in MG63 cells. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s10103-011-1006-yAuthors Tsui Hsien Huang, Graduate School of Dentistry, Chung Shan Medical University Hospital, Chung Shan Medical University, 110, section 1, Chien Kuo N Road, Taichung City, 40201 TaiwanYu Chuan Lu, Graduate School of Dentistry, Chung Shan Medical University Hospital, Chung Shan Medical University, 110, section 1, Chien Kuo N Road, Taichung City, 40201 TaiwanChia Tze Kao, Graduate School of Dentistry, Chung Shan Medical University Hospital, Chung Shan Medical University, 110, section 1, Chien Kuo N Road, Taichung City, 40201 Taiwan ... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5330947 Sat, 15 Oct 2011 15:47:28 +0100 5330947 http://www.medworm.com/index.php?rid=5330948&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2185919147223687%2F Abstract  This meta-analysis was conducted to investigate the efficacy and safety of antimicrobial photodynamic therapy used alone or adjunctive to scaling root planing in patients with chronic periodontitis. The meta-analysis was conducted according to the QUOROM statement and recommendations of the Cochrane Collaboration. An extensive literature search was performed on seven databases, followed by a manual search. Weighted mean differences and 95% confidence intervals were calculated for clinical attachment level, probing depth and gingival recession. The I2 test was used for inter-study heterogeneity; visual asymmetry inspection of the funnel plot, Egger’s regression test and the trim-and-fill method were used to investigate publication bias. At 3 months, significa... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5330948 Sat, 15 Oct 2011 15:47:27 +0100 5330948 http://www.medworm.com/index.php?rid=5330949&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg6367524121v2r0v%2F Content Type Journal ArticleCategory Letter to the EditorPages 1-2DOI 10.1007/s10103-011-1004-0Authors Jan Tunér, Private dental clinic, Spjutvägen 11, 772 32 Grängesberg, SwedenPeter Jenkins, SpectraVet, 736 W Double Shoals Rd, Lawndale, NC 28090, USA Journal Lasers in Medical ScienceOnline ISSN 1435-604XPrint ISSN 0268-8921 (Source: Lasers in Medical Science) Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5330949 Thu, 13 Oct 2011 15:50:38 +0100 5330949 http://www.medworm.com/index.php?rid=5301982&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F35v356t411555447%2F Content Type Journal ArticleCategory Brief ReportPages 1-4DOI 10.1007/s10103-011-1000-4Authors Juan Manuel Segura Palacios, Department of Dermatology, Hospital Carlos Haya, Plaza Hospital Civil s/n, 29009 Málaga, SpainPablo Boixeda, Department of Dermatology, Hospital Ramón y Cajal, Carretera Colmenar km 9.1, 28034 Madrid, SpainJoana Rocha, Department of Dermatology, Hospital de Braga, Braga, PortugalJavier Alcántara González, Department of Dermatology, Hospital Ramón y Cajal, Carretera Colmenar km 9.1, 28034 Madrid, SpainLeticia Alonso Castro, Department of Dermatology, Hospital Ramón y Cajal, Carretera Colmenar km 9.1, 28034 Madrid, SpainCristina de Daniel Rodríguez, Department of Dermatology, Hospital Ramón y Cajal, Carretera Colmenar km 9.1, 28034 Madrid, Spain Journ... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5301982 Thu, 06 Oct 2011 06:27:27 +0100 5301982 http://www.medworm.com/index.php?rid=5301983&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb044631hxju5r288%2F Abstract  The current study was conducted to improve fissure sealing by pre-treatment with Er:YAG laser irradiation in order to remove organic debris. The surface morphology, surface roughness of fissure cavities, and the degree of microleakage after laser treatment were compared with those after bristle brush treatment in vitro. Sixty extracted human teeth were used in this study. The teeth were randomly divided into two groups of 30 each. Artificial fissures were prepared in all teeth into which artificial organic debris was placed. The debris in 30 teeth of one group was removed by means of Er:YAG laser system and the remaining 30 teeth were cleaned using a bristle brush with prophylaxis paste. Surface morphology and surface roughness of were analyzed in ten samples from... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5301983 Tue, 04 Oct 2011 05:56:09 +0100 5301983 http://www.medworm.com/index.php?rid=5293117&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc515m53341682024%2F Abstract  The susceptibility of bacterial cultures in biofilm formations is important for a variety of clinical treatment procedures. Therefore, the aim of the study was to assess the impact of laser-induced antimicrobial photodynamic therapy on the viability of Streptococcus mutans cells employing an artificial biofilm model. Using sterile chambered coverglasses, a salivary pellicle layer was formed in 40 chambers. Streptococcus mutans cells were inoculated in a sterile culture medium. Employing a live/dead bacterial viability kit, bacteria with intact cell membranes stained fluorescent green. Each pellicle-coated test chamber was filled with 0.7 ml of the bacterial suspension and analysed using a confocal laser scanning microscope within a layer of 10 μm at inte... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5293117 Sun, 02 Oct 2011 05:50:04 +0100 5293117 http://www.medworm.com/index.php?rid=5293118&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu1q615176u6848q2%2F Content Type Journal ArticleCategory AbstractsPages 1-43DOI 10.1007/s10103-011-0999-6 Journal Lasers in Medical ScienceOnline ISSN 1435-604XPrint ISSN 0268-8921 (Source: Lasers in Medical Science) Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5293118 Sun, 02 Oct 2011 05:50:02 +0100 5293118 http://www.medworm.com/index.php?rid=5281723&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft04mtw4h12867142%2F Abstract  In the present study, we demonstrated the use of nanoporous zinc oxide (ZnO NPs) in photodynamic therapy. The ZnO NPs structure possesses a high surface to volume ratio due to its porosity and ZnO NPs can be used as an efficient photosensitizer carrier system. We were able to grow ZnO NPs on the tip of borosilicate glass capillaries (0.5 μm diameter) and conjugated this with Photofrin for efficient intracellular drug delivery. The ZnO NPs on the capillary tip could be excited intracellularly with 240 nm UV light, and the resultant 625 nm red light emitted in the presence of Photofrin activated a chemical reaction that produced reactive oxygen species (ROS). The procedure was tested in A-549 cells and led to cell death within a few minutes. The morp... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5281723 Fri, 30 Sep 2011 06:25:04 +0100 5281723 http://www.medworm.com/index.php?rid=5281724&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F22584v2641h04h54%2F Abstract  The aim of this study was to analyze the role of vascular endothelial growth factor (VEGF) in mechanisms of cutaneous remodeling induced by fractional CO2 laser treatment. The dorsal skin of Kunming mice was exposed to a single-pass fractional CO2 laser treatment. Biopsies were taken 1 h, and 1, 3, 7, 14, 28 and 56 days after treatment. Skin samples VEGF expression was evaluated by immunohistochemistry and ELISA, fibroblasts by hematoxylin-eosin staining, and types I and III collagen by ELISA. Staining for VEGF was found in many types of cell including fibroblasts. The amount of VEGF in the skin of laser-treated areas had increased significantly compared to that in the control areas on days 1 and 3 (P < 0.05, P < 0.01, respectively)... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5281724 Fri, 30 Sep 2011 06:25:03 +0100 5281724 http://www.medworm.com/index.php?rid=5281725&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fgw7860631644171n%2F Content Type Journal ArticleCategory Brief ReportPages 1-5DOI 10.1007/s10103-011-0997-8Authors Katrine Togsverd-Bo, Department of Dermatology, Bispebjerg Hospital, University of Copenhagen, Bispebjerg Bakke 23, 2400 Copenhagen, NV, DenmarkUwe Paasch, Department for Dermatology, Venerology and Allergology, University of Leipzig, Philipp-Rosenthal-Strasse 23, 04103 Leipzig, GermanyChristina S. Haak, Department of Dermatology, Bispebjerg Hospital, University of Copenhagen, Bispebjerg Bakke 23, 2400 Copenhagen, NV, DenmarkMerete Haedersdal, Department of Dermatology, Bispebjerg Hospital, University of Copenhagen, Bispebjerg Bakke 23, 2400 Copenhagen, NV, Denmark Journal Lasers in Medical ScienceOnline ISSN 1435-604XPrint ISSN 0268-8921 (Source: Lasers in Medical Science) Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5281725 Fri, 30 Sep 2011 06:25:01 +0100 5281725 http://www.medworm.com/index.php?rid=5281726&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F96pv117433872257%2F Abstract  Increased proliferation after low-level laser irradiation (LLLI) has been well demonstrated in many cell types including mesenchymal stem cells (MSCs), but the exact molecular mechanisms involved remain poorly understood. The aim of this study was to investigate the change in mRNA expression in rat MSCs after LLLI and to reveal the associated molecular mechanisms. MSCs were exposed to a diode laser (635 nm) as the irradiated group. Cells undergoing the same procedure without LLLI served as the control group. Proliferation was evaluated using the MTS assay. Differences in the gene expression profiles between irradiated and control MSCs at 4 days after LLLI were analyzed using a cDNA microarray. Gene ontology and pathway analysis were used to find the key ... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5281726 Thu, 29 Sep 2011 06:16:08 +0100 5281726 http://www.medworm.com/index.php?rid=5281727&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq358k36023010204%2F Abstract  Gingival epithelial cells are the first physical barrier against periodontal pathogenic microorganisms. Bacterial products may penetrate the epithelium and directly disturb its integrity. We investigated the clinical and cytomorphological status of the gingiva in children with gingivitis before and after low-level laser therapy. The study enrolled 130 children divided into three groups: group 1 comprised 50 children with chronic catarrhal gingivitis who received basic treatment, group 2 comprised 50 children with chronic catarrhal gingivitis who received low-level laser treatment in addition to basic treatment, and group 3 comprised 30 children with healthy gingiva as controls. Oral hygiene and the status of the gingiva were assessed using the appropriate indexes ... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5281727 Thu, 29 Sep 2011 06:16:07 +0100 5281727 http://www.medworm.com/index.php?rid=5269144&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy3376372jh8r0556%2F Abstract  The aims of this study were to establish a rat model of carotid artery injury and to evaluate its suitability for evaluating therapeutic agents active against endothelial proliferation. Wistar-Kyoto rats were injected intravenously with the photochemically reactive dyes rose bengal or Evans blue, and the carotid artery was then focally irradiated with laser light of the appropriate wavelength. Histological sections of the carotid artery were analyzed to determine the appropriate parameters for this model. Ferulic acid was used to assess the suitability of this model for drug screening. No animal died as a result of the photochemical treatment. Endothelial proliferation in the carotid artery was observed in rats injected with rose Bengal and exposed to green laser ... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5269144 Wed, 28 Sep 2011 05:51:37 +0100 5269144 http://www.medworm.com/index.php?rid=5269146&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F14g470g24256gwm2%2F Abstract  The goal of this study was to show the modifications in the ultrastructure of the dentin surface morphology following different surface treatments. The stability of the adhesive compound with dentin after laser preparation compared with conventional preparation using different bonding agents was evaluated. An Er,Cr:YSGG laser and 36% phosphoric acid in combination with various bonding systems were used. A total of 100 caries-free human third molars were used in this study. Immediately after surgical removal teeth were cut using a band saw and 1-mm thick dentin slices were created starting at a distance of 4 mm from the cusp plane to ensure complete removal of the enamel. The discs were polished with silicon carbide paper into rectangular shapes to a size of 6... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5269146 Tue, 27 Sep 2011 06:18:10 +0100 5269146 http://www.medworm.com/index.php?rid=5269145&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F9g18551300587196%2F Abstract  A rabbit model of endophthalmitis was established to evaluate the antiinflammatory effect of low-level laser therapy (LLLT) as an adjunct to treatment for Staphylococcus epidermidis endophthalmitis. Rabbits were randomly divided into three groups to receive intravitreal injections into their left eye: group A received 0.5 mg vancomycin (100 μl), group B received 0.5 mg vancomycin + 0.2 mg dexamethasone (100 μl), and group C received 0.5 mg vancomycin (100 μl) and continuous wave semiconductor laser irradiation (10 mW, λ = 632 nm) focused on the pupil. Slit lamp examination and B-mode ultrasonography were conducted to evaluate the symptoms of endophthalmitis. Polymorphonuclear cells and tumour necrosis factor alph... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5269145 Tue, 27 Sep 2011 06:18:10 +0100 5269145 http://www.medworm.com/index.php?rid=5269147&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy35725175v52165p%2F Abstract  The aim of the present study was to determine clinical parameters for the use of Er,Cr:YSGG laser in the treatment of dentine hypersensitivity. Two antagonist areas were determined as control and experimental areas for irradiation in 90 premolar roots. Each surface was conditioned with 24% EDTA (sub-group 1) and 35% phosphoric acid (sub-group 2) and irradiated with the following settings: 1) Er:YAG, 60 mJ, 2 Hz, defocused; groups 2 to 9: irradiation with Er,Cr:YSGG laser, 20 Hz, Z6 tip, 0% of air and water: 2) Er,Cr:YSGG 0.25 W; 3) 0.5 W; 4) 0.75 W; 5) 1.0 W; 6) 1.25 W, 7) 1.50 W, 8) 2 W; 9) 2 W. After irradiation, samples were immersed in methylene blue solution and included in epoxy resin to obtain longitudin... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5269147 Tue, 27 Sep 2011 06:18:07 +0100 5269147 http://www.medworm.com/index.php?rid=5233648&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fph38r8131n621jx0%2F We describe our preliminary experience with Nd-YAG laser waves in the treatment of pilonidal sinus. A total of 41 consecutive patients with pilonidal sinus underwent the intended Nd-YAG laser treatment. Structured telephone interviews were carried out in 37 patients (90%). The median duration of treatment and observation time were 5.1 months and 15.2 months, respectively. Three patients (7%) received additional surgery: two had granulomas removed via a minor excision, and one requested more traditional surgery. At follow-up, 28 out of the 37 patients (75.7%) reported freedom from symptoms without supplementary treatment, and 30 (81%) were symptom-free after supplementary laser treatment and minimal surgery, if needed. We have identified a potential treatment for pilonidal ... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5233648 Fri, 16 Sep 2011 16:52:11 +0100 5233648 http://www.medworm.com/index.php?rid=5233649&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv53p57157433446r%2F In conclusion, although ozone decreased the microtensile bond strength of the self-etch adhesive system to dentin, the Nd:YAG laser and 2% chlorhexidine did not change the microtensile bond strength so in context of the present study it would appear that the Nd:YAG laser and 2% chlorhexidine may be used as pre-restorative sterilization procedures on the dentin prior to the application of a two-step, self-etch adhesive. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s10103-011-0987-xAuthors Evrim Eliguzeloglu Dalkilic, Faculty of Dentistry, Department of Restorative Dentistry, Yuzuncu Yil University, Kampus, Van, 65080 TurkeyHacer Deniz Arisu, Faculty of Dentistry, Department of Restorative Dentistry, Gazi University, Emek, Ankara, 06500 TurkeyBagdagul H... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5233649 Tue, 13 Sep 2011 15:53:03 +0100 5233649 http://www.medworm.com/index.php?rid=5233650&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh6647hx3686l2257%2F Abstract  Dentine hypersensitivity (DH) is a painful condition and is a clinical challenge due to the different treatment strategies available. High-intensity lasers have been studied as a possible option. The aim of this randomized, controlled, double-blind clinical study was to evaluate the effects of Er:YAG and Er,Cr:YSGG lasers on DH. The study group comprised 28 subjects who met the inclusion criteria. A visual analogue scale was used to quantify sensitivity before treatment as baseline, immediately before and immediately after treatment, and 1 week and 1 month after treatment. Teeth were assigned to four groups: group 1 control (no treatment), group 2 Er:YAG laser treatment (2 Hz/32.4 mJ/5.9 J/cm2), group 3 Er,Cr:YSGG laser treatment (0.25 ... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5233650 Tue, 13 Sep 2011 05:48:01 +0100 5233650 http://www.medworm.com/index.php?rid=5217821&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe53p01589707r78n%2F Content Type Journal ArticleCategory Brief ReportPages 1-4DOI 10.1007/s10103-011-0983-1Authors Xingjia Wu, Department of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814, USAHelina Moges, Department of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814, USALuis DeTaboada, PhotoThera Inc, Carlsbad, CA 92008, USAJuanita Anders, Department of Anatomy, Physiology and Genetics, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Road, Bethesda, MD 20814, USA Journal Lasers in Medical ScienceOnline ISSN 1435-604XPrint ISSN 0268-8921 (Source: Lasers in Medical Science) Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5217821 Fri, 09 Sep 2011 16:47:11 +0100 5217821 http://www.medworm.com/index.php?rid=5204397&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd85376th39626773%2F This study aims to research whether the 800-nm laser can be used for non-ablative rejuvenation and its possible mechanism by using an animal model. Eight 2-month-old rats were irradiated with the 800-nm diode laser at 20, 40, and 60 J/cm2, respectively. Skin samples were taken for histological study and dermal thickness measurement at day 30 after laser irradiation. The expression of procollagen type I, III, IV, transforming growth factor-β (TGF-β), Smad2, 3, 4, and phosphorylated-Smad2, 3 in the rat skin was analyzed 24 h after completing all laser treatments by using RT-PCR and Western blot. Immunohistochemistry was performed to evaluate the content of type I collagen in the skin at day 30 after laser irradiation. The 800-nm diode laser treatments markedly improved the histo... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5204397 Sun, 04 Sep 2011 10:47:28 +0100 5204397 http://www.medworm.com/index.php?rid=5174002&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F4260629051268461%2F This study tested whether endurance training associated with LLLT could increase human muscle performance in isokinetic dynamometry when compared to the same training without LLLT. The primary objective was to determine the fatigue index of the knee extensor muscles (FIext) and the secondary objective was to determine the total work of the knee extensor muscles (TWext). Included in the study were 45 clinically healthy women (21 ± 1.78 years old) who were randomly distributed into three groups: CG (control group), TG (training group) and TLG (training with LLLT group). The training for the TG and TLG groups involved cycle ergometer exercise with load applied to the ventilatory threshold (VT) for 9 consecutive weeks. Immediately after each training session, LLLT was applied t... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5174002 Thu, 25 Aug 2011 15:48:16 +0100 5174002 http://www.medworm.com/index.php?rid=5155865&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd1g4888rp78382kv%2F This study clearly demonstrated a significant positive effect of LILT on improvement of nerve conduction velocity on diabetic distal symmetric polyneuropathy (DSP). This finding supports the therapeutic potential of LILT in DSP. Content Type Journal ArticleCategory Original ArticlePages 1-5DOI 10.1007/s10103-011-0977-zAuthors Mohammad Ebrahim Khamseh, Endocrine Research Center (Firouzgar), Institute of Endocrinology and Metabolism (Hemmat Campus), Tehran University of Medical Sciences, Tehran, IranNooshafarin Kazemikho, Endocrine Research Center (Firouzgar), Institute of Endocrinology and Metabolism (Hemmat Campus), Tehran University of Medical Sciences, Tehran, IranRokhsareh Aghili, Endocrine Research Center (Firouzgar), Institute of Endocrinology and Metabolism (Hemmat Campus), T... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5155865 Fri, 19 Aug 2011 06:40:59 +0100 5155865 http://www.medworm.com/index.php?rid=5155866&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl21n7242pp1853w6%2F Abstract  The aim of this study was to compare the effect of the Er,Cr:YSGG laser and different cavity disinfection agents on microleakage of an etch-and-rinse and a self-etch adhesive. Class V preparations were completed on the buccal and lingual surfaces of 30 extracted noncarious human molars. The occlusal margin was placed on enamel and the gingival margin on dentin. Preparations were randomly divided into five experimental groups (n = 12); (1) 2% chlorhexidine gluconate (CHX), (2) propolis, (3) ozone, (4) Er,Cr:YSGG laser, and (5) control (no treatment). Each group was divided into two subgroups according to the adhesive system: etch-and-rinse (Adper Single Bond 2), and a self-etch adhesive (All-Bond SE). The preparations were bulk-filled with a resin composite (Ara... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5155866 Fri, 19 Aug 2011 06:40:58 +0100 5155866 http://www.medworm.com/index.php?rid=5155867&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr342p360u0q6r527%2F Abstract  Selecting the most representative site for biopsy is crucial in establishing a definitive diagnosis of oral epithelial dysplasia. The current process involves clinical examination that can be subjective and prone to sampling errors. The aim of this study was therefore to investigate the use of optical coherence tomography (OCT) for differentiation of normal and dysplastic oral epithelial samples, with a view to developing an objective and reproducible approach for biopsy site selection. Biopsy samples from patients with fibro-epithelial polyps (n = 13), mild dysplasia (n = 2), and moderate/severe dysplasia (n = 4) were scanned at 5-μm intervals using an OCT microscope and subsequently processed and stained with hematoxylin and eosin (H&E). Epithelial d... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5155867 Thu, 18 Aug 2011 05:48:16 +0100 5155867 http://www.medworm.com/index.php?rid=5155868&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F8757724261123424%2F Abstract  The aim of this in vitro study was to compare the microleakage of Er:YAG laser and diamond bur on different bonding systems in class V restorations. Class V cavities were prepared with Er:YAG laser or diamond bur on 80 intact human molars. Teeth were randomly distributed into ten groups and cavities were restored with CeramX duo (DENTSPLY) or Filtek Silorane (3M/ESPE) using different bonding materials (One Coat 7.0 (Coltène), XP Bond (DENTSPLY), Clearfil Protect Bond (Kuraray), AdperSE (3M/ESPE), and Silorane System Adhesive (3M/ESPE). All specimens were subjected to thermocycling and load cycling. After being immersed in silver nitrate dye, the specimens were sectioned. Microleakage was evaluated by stereomicroscope and SEM. Data were statistically analyzed by o... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5155868 Tue, 16 Aug 2011 06:18:17 +0100 5155868 http://www.medworm.com/index.php?rid=5137885&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F938x4159u6555251%2F Content Type Journal ArticlePages 1-15DOI 10.1007/s10103-011-0967-1 Journal Lasers in Medical ScienceOnline ISSN 1435-604XPrint ISSN 0268-8921 (Source: Lasers in Medical Science) Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5137885 Sat, 13 Aug 2011 06:05:25 +0100 5137885 http://www.medworm.com/index.php?rid=5137886&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F824335213818h525%2F Abstract  The aim of this study was to investigate the osteoblastic activity of cells derived from the midpalatal suture upon treatment with low-level laser therapy (LLLT) after rapid maxillary expansion (RME). A total of 30 rats were divided into two groups: experimental I (15 rats with RME without LLLT) and experimental II (15 rats with RME + LLLT). The rats were euthanized at 24 h, 48 h, and 7 days after RME, when the osteoblastic cells derived from the rats’ midpalatal suture were explanted. These cells were cultured for periods up to 17 days, and then in vitro osteogenesis parameters and gene expression markers were evaluated. The cellular doubling time in the proliferative stage (3–7 days) was decreased in cultured cells harvested from the... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5137886 Sat, 13 Aug 2011 06:05:24 +0100 5137886 http://www.medworm.com/index.php?rid=5137887&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F0753731012574352%2F Abstract  During pulsed laser irradiation of dental enamel, laser-induced photoemissions result from the laser–tissue interaction through mechanisms including fluorescence and plasma formation. Fluorescence induced by non-ablative laser light interaction has been used in tissue diagnosis, but the photoemission signal accompanying higher power ablative processes may also be used to provide real-time monitoring of the laser–tissue interaction. The spectral characteristics of the photoemission signals from normal and carious tooth enamel induced by two different pulsed lasers were examined. The radiation sources compared were a high-power extra-long Q-switched Nd:YAG laser operating at a wavelength of 1,066 nm giving pulses (with pulse durations in the range 200–250... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5137887 Sat, 13 Aug 2011 06:05:23 +0100 5137887 http://www.medworm.com/index.php?rid=5137888&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fph49hv618ur237uh%2F We report the successful treatment of TS in 20 patients using a short-pulsed 755-nm alexandrite laser. The 20 patients (skin types II–V) presented with TS lesions on the tip of their nose. All patients received a single treatment (one to three passes) with the laser with cold air cooling but without anaesthesia or analgesia. Treatment parameters were as follows: pulse duration 0.5 ms, fluence 15–17 J/cm2, and spot size 5 mm. The entire procedure required less than 5 min to perform. The patients were followed up for 3 months for any adverse effects or recurrence. In all patients the lesions disappeared immediately after treatment with minimal or no pain. Erythema was minimal and lasted 5–20 min in all patients. Patients were very satisfied. The treat... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5137888 Sat, 13 Aug 2011 06:05:22 +0100 5137888 http://www.medworm.com/index.php?rid=5129990&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F6m6470h625504j0u%2F Abstract  The influence of creatine (Cr) supplementation on cortical and trabecular bone from ovariectomized rats was studied using FT-Raman spectroscopy. The intensity of organic-phase Raman bands was compared to mineral phase ones. Twenty-one female Wistar rats aged 3 months were divided into three groups (n = 7 per group): ovariectomized (OVX), ovariectomized treated with creatine (CRE) and sham-operated (SHAM) groups. Creatine supplementation (300 mg kg−1 day−1) was provided for 8 weeks, starting 12 weeks after ovariectomy. FT-Raman spectroscopy was performed on the right medial femoral mid-shaft (cortical bone) and third lumbar vertebral body (trabecular bone). The integrated intensities of mineral phase (phosphate and carbonate ban... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5129990 Fri, 12 Aug 2011 06:17:10 +0100 5129990 http://www.medworm.com/index.php?rid=5129991&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw0r7h642l12273q1%2F This study evaluated the functional and quantitative differences between the early and delayed use of phototherapy in crushed median nerves. After a crush injury, low-level laser therapy (GaAs) was applied transcutaneously at the injury site, 3 min daily, with a frequency of five treatments per week for 2 weeks. In the early group, the first laser treatment started immediately after surgery, and in the delayed group, after 7 days. The grasping test was used for functional evaluation of the median nerve, before, 10, and 21 days after surgery, when the rats were killed. Three segments of the median nerve were analyzed histomorphometrically by light microscopy and computer analysis. The following features were observed: myelinated fiber and axon diameters, myelin she... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5129991 Thu, 11 Aug 2011 06:57:08 +0100 5129991 http://www.medworm.com/index.php?rid=5106147&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk824212878m84710%2F Abstract  Physical stimulation of body surface points is known to affect various organ functions. In traditional Chinese medicine, so-called acupoints were defined. These points can be physically stimulated to effectively treat various diseases. Here we describe for the first time the effect of CO2 laser stimulation at the acupoints Neiguan (PC-6), Quchi (LI-11), Zusanli (ST-36), and Taichong (LR-3) on heart rate and mean arterial blood pressure in anesthetized rats. CO2 laser stimulation increased the skin surface temperature to 54°C. Our results revealed that the laser stimulation at the left or right PC-6 and LR-3 increased heart rate and mean arterial pressure. There was no response of heart rate and mean arterial pressure during and after stimulation of the left LI-11,... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5106147 Fri, 05 Aug 2011 05:56:42 +0100 5106147 http://www.medworm.com/index.php?rid=5106148&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F17570453v60l0g43%2F This study examined the effects of 635-nm irradiation of P. gingivalis LPS-treated human gingival fibroblasts on inflammatory cytokine profiles and the mitogen-activated protein kinase (MAPK) pathway, which is involved in cytokine production. Gingival fibroblasts treated or not treated with P. gingivalis LPS were irradiated with 635-nm LED light, and cytokine profiles in the supernatant were assessed using a human inflammation antibody array. Expression of cyclooxyginase-2 (COX-2) protein and phosphorylation of extracellular signal-regulated kinase (ERK 1/2), p38, and c-Jun-N-terminal kinase (JNK) were assessed by Western-blot analysis to determine the effects on the MAPK pathway, and prostaglandin E2 (PGE2) in the supernatant was measured using an enzyme-linked immunoassay. COX-2 prot... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5106148 Thu, 04 Aug 2011 15:32:24 +0100 5106148 http://www.medworm.com/index.php?rid=5102845&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F9702478647584211%2F Abstract  Bisphosphonates (BSPs) are used for the treatment of multiple myeloma, metastatic breast and lung cancer, Paget's disease, osteoporosis, hypercalcemia due to malignancy, and many other skeletal diseases. BSPs reduce osteoclastic functions, which result in bone resorption. Bisphosphonates-related osteonecrosis of jaws (BRONJ) is a newly developed term that is used to describe the significant complication in patients receiving bisphosphonates. BSPs are known to exhibit an anti-angiogenetic effect that initiates tissue necrosis of the hard tissue. There is currently no consensus on the correct approach to this issue. The aim of this retrospective study is to compare the effects of laser surgery with biostimulation to conventional surgery in the treatment of BSP-induc... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5102845 Tue, 02 Aug 2011 06:18:44 +0100 5102845 http://www.medworm.com/index.php?rid=5102846&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg44j20x24326273p%2F Abstract  Photodynamic therapy (PDT) is a technique employed in the treatment of several superficial infections, such as caries. PDT uses a non-toxic drug termed photosensitizer (PS) followed by light irradiation. The cytotoxic effects of the therapy are related to the production of reactive species produced after light activation of a photosensitizer, which reacts with surrounding molecules and disrupts several of the cell's functions. Within this context, this study aimed to develop a clinical protocol involving PDT application mediated by aluminum-chloride-phthalocyanine (AlClPc) entrapped in cationic liposomes against cariogenic bacteria in caries lesions. Cationic liposomes were used to delivery AlClPc preferentially to bacterial cells due to the strong anionic superfi... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5102846 Tue, 02 Aug 2011 06:18:43 +0100 5102846 http://www.medworm.com/index.php?rid=5102847&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fph4u617474400h76%2F Abstract  The bond strength of resin composite to Er,Cr:YSGG laser-irradiated enamel and dentin has been evaluated in only a few studies. Therefore, we measured and compared the micro-shear bond strength of composite restorations to enamel and dentin using two different cavity-preparation tools and conditioning methods. One hundred and seventy-five caries-free human third molars were sectioned longitudinally into two different thicknesses and randomly assigned to seven subgroups (n = 25). Enamel groups included laser-cut without etching (LO), laser-cut and laser-etched (LL), laser-cut and acid-etched (LA), bur-cut and laser-etched (BL1), and bur-cut and acid-etched (BA1-comparison group). Dentinal groups included bur-cut and laser-etched (BL2) and bur-cut and acid-etched... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5102847 Tue, 02 Aug 2011 06:18:42 +0100 5102847 http://www.medworm.com/index.php?rid=5085327&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn771113k1004k075%2F Content Type Journal ArticlePages 1-4DOI 10.1007/s10103-011-0970-6Authors Stefano Sivolella, Department of Oral Surgery, Institute of Clinical Dentistry, University of Padova, Via Venezia, 90, 35129 Padova, ItalyMario Berengo, Department of Oral Surgery, Institute of Clinical Dentistry, University of Padova, Via Venezia, 90, 35129 Padova, ItalySerena Cernuschi, Department of Oral Surgery, Institute of Clinical Dentistry, University of Padova, Via Venezia, 90, 35129 Padova, ItalyMarialuisa Valente, Section of Special Pathology, Department of Medical-Diagnostic Sciences and Special Therapies, University of Padova, Padova, Italy Journal Lasers in Medical ScienceOnline ISSN 1435-604XPrint ISSN 0268-8921 (Source: Lasers in Medical Science) Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5085327 Sat, 30 Jul 2011 15:52:02 +0100 5085327 http://www.medworm.com/index.php?rid=5085328&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq3x442875715j104%2F In this study, 120 bovine incisors were distributed into two groups: group C: without bleaching treatment; group B: bleached with 35% hydrogen peroxide. Each group was divided into three subgroups: subgroup N: without laser treatment; subgroup Nd: irradiation with Nd:YAG laser; subgroup Er: irradiation with Er:YAG laser. The adhesive system (Adper Single Bond 2) was then applied and composite buildups were constructed with Filtek Supreme composite. The teeth were sectioned to obtain enamel-resin sticks (1 × 1 mm) and submitted to microtensile bond testing. The data were statistically analyzed by the ANOVA and Tukey tests. The bond strength values in the bleached control group (5.57 MPa) presented a significant difference in comparison to the group bleached and ir... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5085328 Thu, 28 Jul 2011 15:56:50 +0100 5085328 http://www.medworm.com/index.php?rid=5076458&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ftu38331770561k33%2F Abstract  In oral pathology, laser devices can provide important advantages, especially in the treatment of certain lesions. However, there is controversy about the use of some wavelengths in the analysis of suspected dysplastic or neoplastic lesions, raising doubt about the laser’s suitability for use in biopsy procedures. In recent studies, the KTP and diode lasers have been used in biopsy procedures without histological artefacts. The aim of this in vitro study was to evaluate the exact extent of peripheral thermal damage to oral soft tissues caused by an Er:YAG laser (λ 2,940 nm) without water cooling. The study was performed on five swine cadaver tongues. Nine samples from each tongue were taken by the same operator using the Er:YAG laser with increasing energi... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5076458 Wed, 27 Jul 2011 15:48:56 +0100 5076458 http://www.medworm.com/index.php?rid=5076459&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F1320765003m2120v%2F Abstract  The aim of this study was to evaluate the mineral content of dentin prepared using three different desensitizing agents and the Nd:YAG laser. The occlusal third of the crowns of 30 molar teeth were cut with a slow-speed diamond saw sectioning machine under water cooling. Dentin slabs from the 30 teeth were randomly divided into five experimental groups, each comprising six slabs. The five groups were treated as follows: group A, no treatment; group B, treatment with oxalate-containing desensitizing agent (BisBlock); group C, treatment with resin-based desensitizing agent (Admira Protect); group D, treatment with glutaraldehyde-containing desensitizing agent (Systemp); and group E, irradiation with the Nd:YAG laser (DEKATM ) at 0.40 W. The levels of Mg, P, Ca, K, a... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5076459 Tue, 26 Jul 2011 05:49:37 +0100 5076459 http://www.medworm.com/index.php?rid=5061553&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd84025320565m220%2F This study evaluated the microhardness and polymerization shrinkage of flowable resins that are cured using different light sources. Seven flowable resins and two light sources (diode-pumped solid-state (DPSS) laser (LAS) and Optilux 501 (OP)) were chosen for the study. To evaluate the microhardness, a mold (height: 2 mm, inner diameter: 4 mm) was filled with resin and then light cured. The microhardness was measured at the top and bottom surfaces after aging for 24 h. The level of polymerization shrinkage was evaluated for 130 s (during and after the light curing) by measuring the dimensions of the cylindrical shape resin filling. The light intensity of the LAS and OP was approximately 520 mW/cm2 and 800 mW/cm2, respectively. The data for the microhardness an... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5061553 Sat, 23 Jul 2011 15:47:22 +0100 5061553 http://www.medworm.com/index.php?rid=5061552&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F6383l6x151770638%2F Abstract  The purpose of this study was to investigate the surface morphology and roughness of zirconia after different surface treatments. Eighty sintered zirconia specimens were divided into four groups (n = 20) according to the surface treatments received: no treatment, erbium:yttrium-aluminum-garnet (Er:YAG) laser irradiation (400 mJ, 10 Hz, 4 W, 100 MPS, distance: 1 mm), tribochemical silica coating with 30 μm aluminum oxide (Al2O3) modified by silica, and air abrasion with 110 μm Al2O3 particles. After the surface treatments, the surface roughness (Ra in μm) of the specimens was evaluated using a surface texture measuring instrument. Surface morphology of a specimen from each group was evaluated with atomic force microscope (AFM) and... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5061552 Sat, 23 Jul 2011 15:47:22 +0100 5061552 http://www.medworm.com/index.php?rid=5061554&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp2883j710p228u66%2F Content Type Journal ArticlePages 1-1DOI 10.1007/s10103-011-0966-2Authors Viroj Wiwanitkit, Wiwanitkit House, Bangkhae, Bangkok, Thailand 10160 Journal Lasers in Medical ScienceOnline ISSN 1435-604XPrint ISSN 0268-8921 (Source: Lasers in Medical Science) Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5061554 Fri, 22 Jul 2011 17:07:48 +0100 5061554 http://www.medworm.com/index.php?rid=5061556&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F83x45563753g7v15%2F Abstract  In animal and clinical trials low-level laser therapy (LLLT) using red, infrared and mixed wavelengths has been shown to delay the development of skeletal muscle fatigue. However, the parameters employed in these studies do not allow a conclusion as to which wavelength range is better in delaying the development of skeletal muscle fatigue. With this perspective in mind, we compared the effects of red and infrared LLLT on skeletal muscle fatigue. A randomized double-blind placebo-controlled crossover trial was performed in ten healthy male volunteers. They were treated with active red LLLT, active infrared LLLT (660 or 830 nm, 50 mW, 17.85 W/cm2, 100 s irradiation per point, 5 J, 1,785 J/cm2 at each point irradiated, total 20 J irr... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5061556 Thu, 21 Jul 2011 18:12:59 +0100 5061556 http://www.medworm.com/index.php?rid=5061555&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F8m575102p750v068%2F The objective of this study was to investigate the effect of two different surface treatments (Er:YAG laser and bur) and three different numbers of thermal cycling (no aging, 1,000, 5,000, and 10,000 cycles) on the micro-shear bond strength of repaired composite resin. Ninety-six composite blocks (4 mm × 4 mm × 1 mm) obtained with a micromatrix hybrid composite were prepared. The composite blocks were then randomly divided into four groups (n = 24), according to the thermal cycling procedure: (1) stored in distilled water at 37°C for 24 h (control group), (2) 1,000 cycles, (3) 5,000 cycles, and (4) 10,000 cycles. After aging, the blocks were further subdivided into two subgroups (n = 12), according to surface treatment. Bur and laser-treated composite ... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5061555 Thu, 21 Jul 2011 18:12:59 +0100 5061555 http://www.medworm.com/index.php?rid=5061557&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh004317048608l65%2F Abstract  The bond joint between dentin and ceramic is a critical determinant in prosthodontic dentistry. The laser is an alternative to the diamond bur for preparing tooth cavities. However, the impact of lasers on the bond between the laser-irradiated dentin and the ceramic remains a matter of controversy. We determined the shear strength of bonds between ceramic blocks and human dentin discs prepared with either an Er,Cr:YSGG laser or a diamond bur. A total of 180 dentin discs were randomly assigned to four groups. Three groups of discs were prepared with the Er,Cr:YSGG laser irradiation (2 W, 30 Hz, 50% H2O, 70% air) and the fourth group was prepared with a diamond bur. In one of the laser groups the discs surfaces were also treated with phosphoric acid and in ... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5061557 Tue, 19 Jul 2011 23:40:55 +0100 5061557 http://www.medworm.com/index.php?rid=5061558&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F23353003526k4168%2F This study provides experimental evidence that systemic PDT could effectively be applied to systemic and spread tumors, for which tumor formation areas cannot clearly be determined. Content Type Journal ArticlePages 1-8DOI 10.1007/s10103-011-0950-xAuthors Lan Ying Wen, Cancer Research Institute of Medical Science, The Catholic University of Korea College of Medicine, 505 Banpodong, Seocho-ku, Seoul, 137–040 South KoreaSu-Mi Bae, Cancer Research Institute of Medical Science, The Catholic University of Korea College of Medicine, 505 Banpodong, Seocho-ku, Seoul, 137–040 South KoreaHeung-Jae Chun, Institute of Cell and Tissue Engineering, The Catholic University of Korea College of Medicine, 505 Banpodong, Seocho-ku, Seoul, 137–040 South KoreaKye-Shin Park, Diatech Korea, 57-5 Mu... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5061558 Tue, 19 Jul 2011 06:40:27 +0100 5061558 http://www.medworm.com/index.php?rid=5048449&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw02026261862j57m%2F Abstract  The purpose of this article was to analyze the photobiomodulator role of low-level laser therapy (LLLT) on the skeletal muscle remodeling following cryoinjury in rats, focusing the types I and III collagen proteins. Laser phototherapy has been employed to stimulate repair in different tissues. However, its role in skeletal muscle remodeling is not yet well clarified, especially its effect on the collagen component of the extracellular matrix. Fifty adult Wistar rats were divided into four groups: control, sham, cryoinjury, and laser-treated cryoinjury. Laser irradiation was performed three times a week on the injured region using the InGaAlP (indium-gallium-aluminum-phosphorous) laser (660 nm; beam spot of 0.04 cm2, output power of 20 mW, power densi... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5048449 Thu, 14 Jul 2011 16:50:04 +0100 5048449 http://www.medworm.com/index.php?rid=5035530&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk320r2hu702v2633%2F In this study we investigated the healing of open wounds created on the back of rats treated with nicotine with or without LLLT. Of 115 animals, 59 received subcutaneous injections of saline solution, and the others received subcutaneous injections of nicotine (3 mg/kg body weight), twice a day throughout the study period. After 30 days, skin wounds were created on the back of the animals. The animals receiving saline injections were divided into two groups: group 1 (G1, n = 29), in which the wounds were left untreated, and group 2 (G2, n = 30), in which the wounds were treated with LLLT (GaAlAs, 660 nm, 30 mW, 5.57 J/cm2 per point, 0.39 J, 13 s per point, 0.42 W/cm2). The animals receiving nicotine injections were also divided into two groups... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5035530 Wed, 13 Jul 2011 06:18:24 +0100 5035530 http://www.medworm.com/index.php?rid=5035531&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr23583r487r83t77%2F This study showed that all three application times of Er-YAG laser were effective for debonding ceramic laminate veneers by softening the adhesive resin. Content Type Journal ArticlePages 1-4DOI 10.1007/s10103-011-0959-1Authors Mehmet Oguz Oztoprak, Department of Orthodontics, Faculty of Dentistry, Yeditepe University, Bagdat cad. No 238 Göztepe, Istanbul, TurkeyMurat Tozlu, Department of Orthodontics, Faculty of Dentistry, Yeditepe University, Bagdat cad. No 238 Göztepe, Istanbul, TurkeyUfuk Iseri, Department of Prosthodontics, Faculty of Dentistry, Yeditepe University, Istanbul, TurkeyFeyza Ulkur, Department of Orthodontics, Faculty of Dentistry, Yeditepe University, Bagdat cad. No 238 Göztepe, Istanbul, TurkeyTulin Arun, Department of Orthodontics, Faculty of Dentistry, Yedit... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5035531 Tue, 12 Jul 2011 06:03:27 +0100 5035531 http://www.medworm.com/index.php?rid=5035532&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fqh75ju7925x81h66%2F Abstract  Basal cell carcinomas (BCC) have a specialized microvasculature system that can be targeted by the 585-nm pulsed dye laser (PDL) utilizing the theory of selective photothermolysis. Seven volunteers with nine well-defined, biopsy-proven BCCs, were treated with the PDL (585-nm wavelength, a single 450-μs pulse, 7-mm spot size, and 9.0 J/cm2 energy). The lesions, along with a 4-mm border of normal skin were treated. Pain assessment was carried out immediately after the laser treatment. A deep shave biopsy with histological examination occurred 4 weeks after the laser treatment. Pain was assessed on a scale of 0 (no pain) to 10 (worst pain possible). The average patient score was 2.1 (range 1–4). On histology, 5/9 (55.6%) sites demonstrated no evidence of BCC; ... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5035532 Tue, 12 Jul 2011 06:03:24 +0100 5035532 http://www.medworm.com/index.php?rid=5018100&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F5xg2pj1818q03812%2F Abstract  Alopecia areata (AA) is a common autoimmune disease that presents with non-scarring alopecia. It is characterized by intra- or peri-follicular lymphocytic infiltrates composed of CD4+ and CD8+ T-cells on histology. To this day, few treatments are effective for AA. Here we present findings of using a low-level laser comb to alleviate the symptoms of AA in a C3H/HeJ mouse model for AA. Fourteen C3H/HeJ mice with induced AA were used in this study. Two were killed to confirm AA through histology. The remaining 12 mice were randomized into two groups; group I received HairMax LaserComb (wavelength: 655 nm, beam diameter <5 mm; divergence 57 mrad; nine lasers) for 20 s daily, three times per week for a total of 6 weeks; group II was treated similarly,... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5018100 Fri, 08 Jul 2011 06:32:37 +0100 5018100 http://www.medworm.com/index.php?rid=5018101&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F4nk231124k31m5q2%2F Abstract  The aim of this work was to evaluate the effects of low-level laser therapy (LLLT) on exercise performance, oxidative stress, and muscle status in humans. A randomized double-blind placebo-controlled crossover trial was performed with 22 untrained male volunteers. LLLT (810 nm, 200 mW, 30 J in each site, 30 s of irradiation in each site) using a multi-diode cluster (with five spots - 6 J from each spot) at 12 sites of each lower limb (six in quadriceps, four in hamstrings, and two in gastrocnemius) was performed 5 min before a standardized progressive-intensity running protocol on a motor-drive treadmill until exhaustion. We analyzed exercise performance (VO2 max, time to exhaustion, aerobic threshold and anaerobic threshold), levels of oxidativ... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5018101 Fri, 08 Jul 2011 06:32:36 +0100 5018101 http://www.medworm.com/index.php?rid=5018102&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fbh32224w71k51612%2F Content Type Journal ArticlePages 1-6DOI 10.1007/s10103-011-0943-9Authors Assi Levi, The Hadassah-Germany Skin Center, Department of Dermatology, Hadassah-Hebrew University Medical Center, PO Box 12000, Jerusalem, 91010 IsraelItai Ophir, The Hadassah-Germany Skin Center, Department of Dermatology, Hadassah-Hebrew University Medical Center, PO Box 12000, Jerusalem, 91010 IsraelNatalia Lemster, The Hadassah-Germany Skin Center, Department of Dermatology, Hadassah-Hebrew University Medical Center, PO Box 12000, Jerusalem, 91010 IsraelAlexander Maly, Department of Pathology, Hadassah-Hebrew University Medical Center, PO Box 12000, Jerusalem, 91010 IsraelThomas Ruzicka, Department of Dermatology and Allergy, Ludwig-Maximilian-University, Munich, GermanyArieh Ingber, The Hadassah-Germany Ski... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5018102 Wed, 06 Jul 2011 05:56:02 +0100 5018102 http://www.medworm.com/index.php?rid=5018103&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2r5x166413015u81%2F Abstract  Little is known about the benefits of low-level laser therapy (LLLT) on improvement of stability of dental implants. The aim of this randomized clinical study was to assess the LLLT effect on implants stability by means of resonance frequency analysis (RFA). Thirty implants were distributed bilaterally in the posterior mandible of eight patients. At the experimental side, the implants were submitted to LLLT (830 nm, 86 mW, 92.1 J/cm2, 0.25 J, 3 s/point, at 20 points), and on the control side, the irradiation was simulated (placebo). The first irradiation was performed in the immediate postoperative period, and it was repeated every 48 h in the first 14 days. The initial implant stability quotient (ISQ) of the implants was measured... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5018103 Wed, 06 Jul 2011 05:56:01 +0100 5018103 http://www.medworm.com/index.php?rid=5018104&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh814357l4q570581%2F In this study, we examined the effect of LLLT (low-level laser therapy) on the healing of extraction sockets in diabetic and healthy rats. Forty-eight Sprague-Dawley rats were divided into normal (n = 24) and diabetic (n = 24) rats, and streptozotocin (STZ) injection was used to induce diabetes in the latter. The left and right maxillary first molars of all the rats were extracted. In the non-diabetic rats, the left extraction sockets were not irradiated (group 1) and the right ones were irradiated daily for 3, 5, 7, and 14 days after extraction with a galium-aluminum-arsenide (GaAlAs) diode laser (group 2), and in the diabetic rats, similarly the left ones were not irradiated (group 3) and the right ones were irradiated (group 4). Specimens acquired at these intervals we... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5018104 Wed, 06 Jul 2011 05:55:59 +0100 5018104 http://www.medworm.com/index.php?rid=5018105&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg77072kut81327l8%2F Abstract  The theory of selective photothermolysis (SP) is used in many fields of laser surgery and medicine. As several parameters and a number of complicated photothermal interactions are involved in SP, numerical simulations have been providing an important and effective way in SP studies. However, with different photothermal models of SP, simulated results differ considerably. In addition, insufficient attention has been paid to tissue pressure variation during SP in these models, so that vessel rupture and other clinical phenomena cannot be explained. A novel photothermal model of SP was proposed using a Monte Carlo method to simulate the laser transport in the tissue, a heat transfer equation with dynamically changing vaporization temperature to calculate the temperat... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=5018105 Wed, 06 Jul 2011 05:55:57 +0100 5018105 http://www.medworm.com/index.php?rid=4991884&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu42278h3526h06r6%2F Abstract  The aim of this study was to examine the cytomorphological changes occurring in the buccal mucosa in patients treated with low-level 1,064-nm laser radiation. Seventeen individuals (12 males, five females) 18–24 years of age were included in the study. Low-level 1,064-nm laser radiation was applied to the right buccal mucosa near the premolar region; this therapy was repeated for 10 days. Buccal epithelial cells were collected from the right and left premolar regions of the individuals with a brush before and after therapy. The specimens collected from the left side were measured cytomorphometrically and used for the control group. Student’s t test was used for statistical comparison of the values of the buccal epithelial cells collected from individu... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4991884 Tue, 28 Jun 2011 15:51:28 +0100 4991884 http://www.medworm.com/index.php?rid=4974769&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk686822v553g9538%2F Abstract  Low-intensity laser therapy is based on the excitation of endogenous chromophores in biotissues and free-radical generation could be involved in its biological effects. In this work, the effects of the low-intensity infrared laser on plasma protein content and oxidative stress in blood from Wistar rats were studied. Blood samples from Wistar rats were exposed to low-intensity infrared laser in continuous wave and pulsed-emission modes at different fluencies. Plasma protein content and two oxidative stress markers (thiobarbituric acid-reactive species formation and myeloperoxidase activity) were carried out to assess the effects of laser irradiation on blood samples. Low-intensity infrared laser exposure increases plasma protein content, induces lipid peroxidation,... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4974769 Thu, 23 Jun 2011 16:33:10 +0100 4974769 http://www.medworm.com/index.php?rid=4967659&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F4673412gp1452124%2F Abstract  Both Nd:YAG and Er:YAG lasers have been suggested as root canal disinfection aids. The aim of this in vitro study is to compare both wavelengths in terms of irradiation dose required for microbial inactivation, to quantify these irradiation doses and to investigate the influence of certain (laser) parameters on the antimicrobial efficacy. Agar plates containing a uniform layer of Enterococcus faecalis, Candida albicans or Propionibacterium acnes were mounted perpendicularly underneath the laser handpieces (5 mm spot). The Er:YAG laser was operated in single-pulse mode. Pulse energies of 40–400 mJ and pulse lengths of 100, 300, 600, and 1,000 μs were tested. After incubation at 37°C for 48 h, growth on the plates was scored. The pulse energy ... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4967659 Tue, 21 Jun 2011 18:33:57 +0100 4967659 http://www.medworm.com/index.php?rid=4959315&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy22528687077q36m%2F In conclusion, this is the first prospective study to show that clinical healing of leukoplakia treated by laser surgery may be accompanied by altered cell turnover in 20% of the cases. Ki67, as a marker of proliferative status, may be a prognostic indicator in the mucosa replacing the lesion. Content Type Journal ArticlePages 1-6DOI 10.1007/s10103-011-0941-yAuthors Lucio Montebugnoli, Department of Oral Science, University of Bologna, Via S. Vitale 59, 40125 Bologna, ItalyFrancesca Frini, Postgraduate School of Oral and Maxillofacial Surgery, University of Bologna, Bologna, ItalyDavide Bartolomeo Gissi, Department of Oral Science, University of Bologna, Via S. Vitale 59, 40125 Bologna, ItalyAndrea Gabusi, Department of Oral Science, University of Bologna, Via S. Vitale 59, 40125 ... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4959315 Mon, 20 Jun 2011 14:17:54 +0100 4959315 http://www.medworm.com/index.php?rid=4959314&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F8321012x1074473k%2F Abstract  Experimental studies in animals and in vitro have shown the usefulness of photodynamic therapy (PDT) as an adjunct to periodontal treatment. The aim of this study was to evaluate the long-term clinical and microbiological effects of PDT associated with nonsurgical periodontal treatment. Three sites in each of 33 patients with chronic periodontitis were randomly allocated in a split-mouth design to a treatment group: (1) scaling and root planing (SRP group); (2) SRP and irrigation with toluidine blue O (TBO group); and (3) SRP, irrigation with TBO and low-level laser irradiation (PDT group). Clinical parameters including visible plaque index, bleeding gingival index, bleeding on probing, probing depth, gingival recession and clinical attachment level were measured ... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4959314 Mon, 20 Jun 2011 14:17:54 +0100 4959314 http://www.medworm.com/index.php?rid=4932486&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F742356p1422612t2%2F This study seeks to evaluate the enamel surface characteristics of teeth after debonding of ceramic brackets with or without laser light. Eighty premolars were bonded with either of the chemically retained or the mechanically retained ceramic brackets and later debonded conventionally or through a CO2 laser (188 W, 400 Hz). The laser was applied for 5 s with scanning movement. After debonding, the adhesive remnant index (ARI), the incidence of bracket and enamel fracture, and the lengths, frequency, and directions of enamel cracks were compared among the groups. The increase in intrapulpal temperature was measured in ten extra specimens. The data were analyzed with SPSS software. There was one case of enamel fracture in the chemical retention/conventional debonding group. Wh... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4932486 Sat, 11 Jun 2011 06:37:44 +0100 4932486 http://www.medworm.com/index.php?rid=4901399&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd0667524132j75v7%2F Abstract  Phototherapy with low-level coherent light (laser) has been reported as an analgesic and anti-inflammatory as well as having a positive effect in tissue repair in orthodontics. However, there are few clinical studies using low-level LED therapy (non-coherent light). The aim of the present study was to analyze the pain symptoms after orthodontic tooth movement associated with and not associated with coherent and non-coherent phototherapy. Fifty-five volunteers (mean age = 24.1 ± 8.1 years) were randomly divided into four groups: G1 (control), G2 (placebo), G3 (protocol 1: laser, InGaAlP, 660 nm, 4 J/cm2, 0.03 W, 25 s), G4 (protocol 2: LED, GaAlAs, 640 nm with 40 nm full-bandwidth at half-maximum, 4 J/cm2, 0.10 W, ... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4901399 Mon, 30 May 2011 16:54:06 +0100 4901399 http://www.medworm.com/index.php?rid=4901400&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm1633131r7522160%2F Abstract  Pain, swelling, and trismus are the most common complications after surgical removal of impacted lower third molars. The aim of this study was to evaluate the analgesic and anti-inflammatory effects of a low-level laser therapy (Laser Smile™, Biolase®, San Clemente, USA) applied to the wound appeared after the surgical removal of impacted lower third molars. A prospective, randomized, and double-blind study was undertaken in 20 healthy patients with two symmetrically impacted lower third molars. The application of a low-level laser was made randomly on one of the two sides after surgery. The experimental side received 5 J/cm2 of energy density, a wavelength of 810 nm, and an output power of 0.5 W. On the control side, a handpiece was applied intra... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4901400 Thu, 26 May 2011 16:08:41 +0100 4901400 http://www.medworm.com/index.php?rid=4901401&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv25634715472344k%2F Abstract  Low-level laser therapy is a tool employed in the management of post-operative inflammation process and in the enhancement of reparative process. The aim of the study was to perform histological evaluation of dental and periodontal ligament of rats central upper-left incisor teeth re-implanted and irradiated with low-level laser (InGaAl, 685 nm, 50 J/cm2) 15, 30, and 60 days after re-implantation. Seventy-two male rats had the central upper left incisor removed and kept for 15 min on dry gauze before replantation. Laser was irradiated over the root surface and empty alveolus prior replantation and over surrounding mucosa after the re-implantation. After histological procedures, all slices were analyzed regarding external resorption area and histologi... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4901401 Thu, 26 May 2011 16:08:40 +0100 4901401 http://www.medworm.com/index.php?rid=4901402&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx41qw52p52620m36%2F This study was performed according to a random split-mouth-design, controlled clinical trial for sulcular debridement on 40 teeth from 20 patients with generalized moderate chronic periodontitis. The periodontal healing outcomes were compared after periodontal treatment with either SRP + NDL at 1 W (test side) or SRP (control side). Plaque index (PI), gingival index (GI), probing pocket depth (PPD), and clinical attachment level (CAL) were recorded, and samples of gingival crevicular fluid (GCF) were taken at baseline and post-therapy (3 and 9 months after treatment). The GCF samples were analyzed for IL-1β and MMP-8. There was postoperative improvement of all clinical parameters in both groups, but test side GI, PPD, and CAL recovery was higher than that of the control side (p... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4901402 Wed, 25 May 2011 16:03:16 +0100 4901402 http://www.medworm.com/index.php?rid=4901404&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm2q9367p2t44107u%2F Content Type Journal ArticlePages 1-4DOI 10.1007/s10103-011-0919-9Authors Tahwinder Upile, UCL Department of Surgery, University College London Medical School, London, UKWaseem Jerjes, UCL Department of Surgery, University College London Medical School, London, UKJaspal Mahil, Department of Head and Neck Surgery, Barnet and Chase Farm Hospitals NHS Trust, London, UKColin Hopper, UCL Department of Surgery, University College London Medical School, London, UKHolger Sudhoff, University Hospital Bielefeld, Bielefeld, Germany Journal Lasers in Medical ScienceOnline ISSN 1435-604XPrint ISSN 0268-8921 (Source: Lasers in Medical Science) Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4901404 Wed, 25 May 2011 16:03:14 +0100 4901404 http://www.medworm.com/index.php?rid=4901403&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw51r1807826w8755%2F Abstract  Several studies suggest a biomodulatory influence of low-level laser irradiation in the inflammatory and reparative processes of dental tissues. The aim of this study was to investigate the stimulatory effect of 808-nm laser irradiation on root development of rat molars and also to evaluate the histological reaction of pulp and periapical tissues. Twenty-four 30-day-old Wistar male rats were randomly assigned to three-time and five-time laser therapy groups. After initial x-ray, using mammography equipment, laser energy was applied at a wavelength of 808 nm (2 J/cm2, 100 mW, 20 s) to the midroot area of the lower molars of one side of mouth at repeated intervals of the 48 h. The animals were killed 1 day after the final treatment, and ... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4901403 Wed, 25 May 2011 16:03:14 +0100 4901403 http://www.medworm.com/index.php?rid=4901405&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd34418766617615x%2F Abstract  This paper reports an investigation into the characteristics of femtosecond laser (800-nm central wavelength) in the ablation of human dental enamel, dentine, and cementum at various laser fluences from 0.2 to 3.68 J/cm2 with single and multiple pulses. The femtosecond laser interaction with cementum is reported for the first time. Ablation thresholds were determined to be 0.58, 0.44, and 0.51 J/cm2 for enamel, dentine, and cementum, respectively. Under the average laser fluences of 1.13 to 3.68 J/cm2, clean ablated surfaces without debris and microcracks were obtained. Laser fluence was found to influence the ablated diameter and depth, whereas under a certain fluence, pulse number only affects the depth, without affecting the diameter. The ablation ... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4901405 Tue, 24 May 2011 16:02:12 +0100 4901405 http://www.medworm.com/index.php?rid=4852340&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ftn31722663268102%2F Abstract  Bone marrow-derived mesenchymal stem cells (BMSCs) are promising for use in regenerative medicine. Several studies have shown that low-level laser irradiation (LLLI) could affect the differentiation and proliferation of MSCs. The aim of this study was to examine the influence of LLLI at different energy densities on BMSCs differentiation into neuron and osteoblast. Human BMSCs were cultured and induced to differentiate to either neuron or osteoblast in the absence or presence of LLLI. Gallium aluminum arsenide (GaAlAs) laser irradiation (810 nm) was applied at days 1, 3, and 5 of differentiation process at energy densities of 3 or 6 J/cm2 for BMSCs being induced to neurons, and 2 or 4 J/cm2 for BMSCs being induced to osteoblasts. BMSCs proliferation ... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4852340 Thu, 19 May 2011 16:34:32 +0100 4852340 http://www.medworm.com/index.php?rid=4861352&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj5512712v0ur0778%2F Content Type Journal ArticlePages 1-5DOI 10.1007/s10103-011-0929-7Authors Marita Luomanen, Institute of Biomedicine/Anatomy, University of Helsinki, PO Box 63, Haartmaninkatu 8, 00014 Helsinki, FinlandSatu Alaluusua, Institute of Dentistry/Department of Pediatric and Preventive Dentistry, University of Helsinki, PO Box 41, 00014 Helsinki, Finland Journal Lasers in Medical ScienceOnline ISSN 1435-604XPrint ISSN 0268-8921 (Source: Lasers in Medical Science) Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4861352 Thu, 19 May 2011 16:34:30 +0100 4861352 http://www.medworm.com/index.php?rid=4819755&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu28q220351114k18%2F Abstract  The optical properties of bovine ocular tissues have been determined at laser wavelengths in the near-infrared (NIR) region. The inverse adding doubling (IAD), Kubelka–Munk (KM), and inverse Monte Carlo (IMC) methods were applied to the measured values of the total diffuse transmission, total diffuse reflection, and collimated transmission to determine the optical absorption and scattering coefficients of the bovine cornea, lens and retina from 750 to 1,000 nm using a CW Ti:sapphire laser. The optical properties obtained from these three methods have been compared and are discussed. Content Type Journal ArticlePages 1-10DOI 10.1007/s10103-011-0927-9Authors Brian G. Yust, Department of Physics and Astronomy, University of Texas at San Antonio, San Anton... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4819755 Tue, 10 May 2011 06:05:28 +0100 4819755 http://www.medworm.com/index.php?rid=4819756&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk1122x98750p3147%2F This study evaluated the influence of the dentin permeability on the transdentinal LED light (630 nm) transmission. Forty-five 0.5-mm-thick dentin disks were prepared from the coronal dentin of extracted sound human molars. An initial measurement of transdentinal LED light transmission was carried out by illuminating the discs in the occlusal-to-pulpal direction onto a light power sensor to determine light attenuation. The discs were treated with EDTA for smear layer removal, subjected to analysis of hydraulic conductance, and a new measurement of transdentinal LED light transmission was taken. Spearman’s correlation coefficient was used for analysis of data and showed a weak correlation between dentin permeability and light attenuation (coefficient = 0.19). This result i... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4819756 Tue, 10 May 2011 06:05:27 +0100 4819756 http://www.medworm.com/index.php?rid=4819757&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fbh31283x14tw222j%2F Abstract  Low-level laser therapy is used in the treatment of many diseases based on its biostimulative effect. However, the photobiological basis for its mechanism of action and adverse effects are not well understood. The aim of this study, using experimental models, was to evaluate the effects of laser on bacterial plasmids in alkaline agarose gel electrophoresis and Escherichia coli cultures. The electrophoretic profile of bacterial plasmids in alkaline agarose gels were used for studying lesions in DNA exposed to infrared laser. Transformation efficiency and survival of Escherichia coli AB1157 (wild-type), BH20 (fpg/mutM - ), BW9091 (xth-), and DH5αF’Iq (recA - ) cells harboring pBSK plasmids were used as experimental models to assess the effect of laser on pla... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4819757 Tue, 10 May 2011 06:05:26 +0100 4819757 http://www.medworm.com/index.php?rid=4812105&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp215084317j24054%2F Abstract  Scaling root planing (SRP) has been proven efficacious as the traditional treatment approach for chronic periodontitis. However, important limitations such as difficult access in deep pockets, grooves, and furcations have led to the development of new therapeutic strategies. The erbium-doped:yttrium-aluminium-garnet (Er:YAG) laser is one of the most promising laser types for periodontal therapy. Its efficacy in radicular debris removal and root smoothing has been proven in vitro. However, the clinical effectiveness of the Er:YAG laser remains controversial. The aim of the present systematic review was to systemically assess the scientific evidence for the effectiveness of Er:YAG laser compared to SRP in the treatment of chronic periodontitis. Electronic database s... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4812105 Fri, 06 May 2011 16:19:30 +0100 4812105 http://www.medworm.com/index.php?rid=4812106&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp1wk856544u75301%2F The objective of the present study was to evaluate the effect of 940 nm wavelength light emitting diode (LED) phototherapy on nerve regeneration in rats. Forty male Wistar rats weighing approximately 300 g each were divided into four groups: control (C); control submitted to LED phototherapy (CLed); Sciatic Nerve Lesion without LED phototherapy (L); Sciatic Nerve Lesion with LED phototherapy (LLed). The lesion was caused by crushing the right sciatic nerve. A dose of 4 J/cm2 was used for ten consecutive days beginning on the first postoperative day. Groups C and L were submitted to the same procedure as the LLed group, but the equipment was turned off. The LED phototherapy with 940 nm wavelength reduced the areas of edema, the number of mononuclear cells present in... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4812106 Thu, 05 May 2011 15:45:38 +0100 4812106 http://www.medworm.com/index.php?rid=4812107&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F76260l71vv0r7390%2F Abstract  The aim of this controlled animal study was to investigate the effect of low-level laser therapy (LLLT) administered 30 min after injury to the Achilles tendon. The study animals comprised 16 Sprague Dawley male rats divided in two groups. The right Achilles tendons were injured by blunt trauma using a mini guillotine, and were treated with LLLT or placebo LLLT 30 min later. The injury and LLLT procedures were then repeated 15 hours later on the same tendon. One group received active LLLT (λ = 904 nm, 60 mW mean output power, 0.158 W/cm2 for 50 s, energy 3 J) and the other group received placebo LLLT 23 hours after LLLT. Ultrasonographic images were taken to measure the thickness of the right and left Achilles tendons. Animal... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4812107 Thu, 05 May 2011 15:45:35 +0100 4812107 http://www.medworm.com/index.php?rid=4812108&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj651600402883801%2F Abstract  The purpose of this study was to investigate the histological changes that occur in rat soft and hard tissues after Er,Cr:YSGG laser surgery. Each of 20 rats was submitted to four procedures which were randomly distributed to the right and left sides of the animal: procedure 1 dorsal incision with a scalpel; procedure 2 dorsal incision with a 2.0-W Er,Cr:YSGG laser; procedure 3 skull defect created with a diamond bur; procedure 4 skull defect created with a 3.0-W Er,Cr:YSGG laser. The animals were killed 3, 7, 15 and 30 days after surgery, and histological examinations were performed. The histometric analysis of the bone defects was evaluated using an unpaired t-test. Initially, the dorsum showed more histological signs of repair following procedure 1, although ... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4812108 Thu, 05 May 2011 05:44:23 +0100 4812108 http://www.medworm.com/index.php?rid=4794335&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv301m537612056kj%2F Abstract  Rheumatoid arthritis (RA) is an inflammatory joint disorder whose progression leads to the destruction of cartilage and bone. Although low-level laser irradiation (LLLI) is currently being evaluated for the treatment of RA, the molecular mechanisms underlying its effectiveness remain unclear. To investigate possible LLLI-mediated antiinflammatory effects, we utilized a collagen-induced arthritis (CIA) rat model and analyzed gene expression profiles in the synovial membranes of the knee joint. Total RNA was isolated from the synovial membrane tissue of the joints of untreated CIA rats or CIA rats treated with LLLI (830 nm Ga-Al-As diode), and gene expression profiles were analyzed by DNA microarray (41,000 rat genes), coupled with Ingenuity pathways analy... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4794335 Tue, 03 May 2011 15:33:58 +0100 4794335 http://www.medworm.com/index.php?rid=4794336&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fju870120r78m6945%2F Abstract  It has been reported that low-power laser irradiation (LLI) can modulate various biological processes including cell proliferation. Some reports suggest that LLI interferes with the cell cycle and inhibits cell proliferation, while others suggest that LLI has a stimulatory effect. Mechanisms underlying the effects of LLI remain unclear. Since the effects of LLI on cancer cells are not well understood, with the aim of developing an LLI therapy for malignant glioblastoma, we investigated the effects of LLI on the cell proliferation of the human-derived glioblastoma cell line A-172. Glioblastoma cell cultures were irradiated with a diode laser at a wavelength of 808 nm and the effects on cell viability and proliferation were examined. Cell counting at 24 and 48&... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4794336 Tue, 03 May 2011 05:57:09 +0100 4794336 http://www.medworm.com/index.php?rid=4779814&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F5l54qr4103161214%2F Abstract  Laser light is frequently used in both diagnostics and treatment of patients. For any laser treatment to be effective it is important to deliver the correct dose at the treatment site. Human skin scatters and absorbs laser light in the visible wavelength region, which results in a decrease in fluence some distance into the skin. Computer simulations can be used to predict the fluence at the treatment site. Liquid and solid phantoms were prepared and the optical properties were measured. These values were then used as input values to a commercial software package simulating the different layers of skin representing phantoms. The transmission and reflected fractions of the different phantoms were measured with an integrating sphere and compared with the computer sim... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4779814 Sun, 01 May 2011 05:42:05 +0100 4779814 http://www.medworm.com/index.php?rid=4779815&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq715010576226516%2F Abstract  We review the different spectroscopic techniques including the most recent laser-induced breakdown spectroscopy (LIBS) for the characterization of materials in any phase (solid, liquid or gas) including biological materials. A brief history of the laser and its application in bioscience is presented. The development of LIBS, its working principle and its instrumentation (different parts of the experimental set up) are briefly summarized. The generation of laser-induced plasma and detection of light emitted from this plasma are also discussed. The merit and demerits of LIBS are discussed in comparison with other conventional analytical techniques. The work done using the laser in the biomedical field is also summarized. The analysis of different tissues, mineral an... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4779815 Fri, 29 Apr 2011 23:19:05 +0100 4779815 http://www.medworm.com/index.php?rid=4770698&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx62554j685288830%2F The objective of this study was to evaluate efficacy and safety profile of laser-assisted hair removal in individuals with Fitzpatrick type IV–VI skin using long-pulsed Nd:YAG laser. Retrospective data was collected from 150 individuals with Fitzpatrick type IV–VI skin who underwent laser-assisted hair removal. This included area treated, fluence, number of treatments, and outcome. Data was also gathered on patient satisfaction and complications. The most common phototype was type IV (94%). The most frequently treated area was the face (84.7%) followed by the underarms and legs. Among the facial areas, the chin was the most frequently treated area followed by the upper lip and jaw line. The mean number of treatments was 8.9 (range 4–22). The maximum fluence averaged 26.8 Joules... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4770698 Mon, 25 Apr 2011 16:46:43 +0100 4770698 http://www.medworm.com/index.php?rid=4770699&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn22424v568x20290%2F Abstract  This prospective clinical study evaluated the survival rate and the implant-crown success of 201 direct laser metal forming (DLMF) implants in different clinical applications, after short-term follow-up of functional loading. At the 1-year scheduled follow-up examination, several clinical, radiographic, and prosthetic parameters were assessed. Success criteria included absence of pain, sensitivity, suppuration, exudation; absence of implant mobility; absence of continuous peri-implant radiolucency, DIB <1.5 mm; absence of prosthetic complications at the implant-abutment interface. A total of 201 implants (106 maxilla, 95 mandible) were inserted in 62 patients (39 males, 23 females; aged between 26 and 65 years) in eight different clinical centers. The... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4770699 Mon, 25 Apr 2011 16:46:41 +0100 4770699 http://www.medworm.com/index.php?rid=4723069&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F3425153l04115l56%2F Abstract  The use of the CO2 laser in the management of oral dysplastic lesions has become a more common practice. Very few studies have evaluated recurrence, residual disease malignant transformation, and overall outcome in patients undergoing such a procedure. In this prospective study, a total of 123 oral dysplastic lesions from 77 consecutive patients were treated with the CO2 laser (resection and/or ablation). The average age was 58 ± 4.8 years. The patients’ recovery was uneventful and no complications were reported. Comparisons with the clinical and histopathological features and rate of recurrence as well as malignant transformation were made. The patients were followed-up for a mean of 6.4 years, and biopsies taken in case of changes suggestive of ma... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4723069 Thu, 14 Apr 2011 17:03:03 +0100 4723069 http://www.medworm.com/index.php?rid=4723071&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F9n11r3k533j6t7k6%2F Abstract  The aim of this study was to evaluate the effectiveness of photodynamic therapy (PDT) for the disinfection of complete dentures. Biofilm samples were collected from dentures of 60 denture users who were randomly divided into four experimental groups (n = 15 each): subjects whose maxillary dentures were sprayed with 50 and 100 mg/l of Photogem® suspension (groups P50S and P100S) and patients whose maxillary dentures were treated with 50 and 100 mg/l of Photogem® gel (groups P50G and P100G). Dentures with photosensitizers were left in the dark for 30 min (pre-irradiation time) and then irradiated with blue LED light at 37.5 J/cm2 (26 min). Denture samples were taken with sterile cotton swab before (left side surfaces) and after (right sid... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4723071 Tue, 12 Apr 2011 05:50:39 +0100 4723071 http://www.medworm.com/index.php?rid=4723070&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh9j4442qv3785q85%2F Abstract  Arthritis of the knee is the most common type of joint inflammatory disorder and it is associated with pain and inflammation of the joint capsule. Few studies address the effects of the 810-nm laser in such conditions. Here we investigated the effects of low-level laser therapy (LLLT; infrared, 810-nm) in experimentally induced rat knee inflammation. Thirty male Wistar rats (230–250 g) were anesthetized and injected with carrageenan by an intra-articular route. After 6 and 12 h, all animals were killed by CO2 inhalation and the articular cavity was washed for cellular and biochemical analysis. Articular tissue was carefully removed for real-time PCR analysis in order to evaluate COX-1 and COX-2 expression. LLLT was able to significantly inhibit the total nu... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4723070 Tue, 12 Apr 2011 05:50:39 +0100 4723070 http://www.medworm.com/index.php?rid=4723073&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp681j5528643526t%2F In conclusion, both LLL and LED irradiation reduced venom-induced local effects even though symptoms were already present. Thus, the effect of phototherapy in reducing local effects induced by BmV may be clinically relevant. Content Type Journal ArticlePages 1-6DOI 10.1007/s10103-011-0914-1Authors Nikele Nadur-Andrade, Laboratory of Physiology and Pharmacology, Institute of Research and Development, University of Vale do Paraíba, São José dos Campos, BrazilAna Maria Barbosa, Laboratory of Physiology and Pharmacology, Institute of Research and Development, University of Vale do Paraíba, São José dos Campos, BrazilFernando Pereira Carlos, Rehabilitation Sciences Master’s Program, Nove de Julho University – UNINOVE, Av. Francisco Matarazzo, 612 São Paulo, SP, BrazilCarlos ... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4723073 Tue, 12 Apr 2011 05:50:36 +0100 4723073 http://www.medworm.com/index.php?rid=4723072&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fpx131372h21183h3%2F In this study, a thulium (Tm:YAP) laser system was developed for brain surgery applications. As the Tm:YAP laser is a continuous-wave laser delivered via silica fibers, it would have great potential for stereotaxic neurosurgery with highest local absorption in the IR region. The laser system developed in this study allowed the user to set the power level, exposure time, and modulation parameters (pulse width and on-off cycles). The Tm:YAP laser beam (200–600 mW, 69–208 W/cm2) was delivered from a distance of 2 mm to cortical and subcortical regions of ex-vivo Wistar rat brain tissue samples via a 200-μm-core optical fiber. The system performance, dosimetry study, and ablation characteristics of the Tm:YAP laser were tested at different power levels by maximizing th... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4723072 Tue, 12 Apr 2011 05:50:36 +0100 4723072 http://www.medworm.com/index.php?rid=4708728&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F3377735q4j256230%2F Abstract  The aim of this study was to evaluate the effects of different techniques of surface treatment on the microleakage of a fissure sealant in molar teeth. A total of 50 freshly extracted noncarious human third molars were randomly assigned to one of five groups. Occlusal fissures were treated with one of the following: acid etching with 35% orthophosphoric acid (group 1); fissurotomy with a Fissurotomy Micro NTF metal bur (group 2); laser etching with an Er,Cr:YSGG laser at 2 W and 20 Hz (group 3); laser etching with an Er,Cr:YSGG laser at 2 W and 40 Hz (group 4); and air abrasion for 20 s with 30-µm Al2O3 particles via a CoJet Prep device (group 5). After surface pretreatment, a resin-based sealant was applied to the fissures. The sample tee... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4708728 Fri, 08 Apr 2011 07:07:08 +0100 4708728 http://www.medworm.com/index.php?rid=4696051&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb136180626404632%2F Abstract  The pulsed dye laser is an effective and established treatment for port-wine stains and has become the generally accepted standard of care. However, in many cases, complete clearance cannot be achieved as a significant proportion of lesions become resistant to treatment. Multiple passes or pulse-stacking techniques have been used to improve the extent and rate of fading, but concerns over increased adverse effects have limited this clinical approach. In this work, a double-pass technique with the pulsed dye laser has been described, which may allow for increased depth of vascular injury, greater efficacy, and an acceptable risk profile. Our aim was to determine the efficacy and the rate of side-effects for a double-pass protocol with a pulsed dye laser (PDL) to tr... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4696051 Thu, 07 Apr 2011 17:07:48 +0100 4696051 http://www.medworm.com/index.php?rid=4692586&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff3617621l0k15161%2F This study presents the results of Raman spectroscopy applied to the classification of arterial tissue based on a simplified model using basal morphological and biochemical information extracted from the Raman spectra of arteries. The Raman spectrograph uses an 830-nm diode laser, imaging spectrograph, and a CCD camera. A total of 111 Raman spectra from arterial fragments were used to develop the model, and those spectra were compared to the spectra of collagen, fat cells, smooth muscle cells, calcification, and cholesterol in a linear fit model. Non-atherosclerotic (NA), fatty and fibrous-fatty atherosclerotic plaques (A) and calcified (C) arteries exhibited different spectral signatures related to different morphological structures presented in each tissue type. Discriminant analys... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4692586 Tue, 05 Apr 2011 16:58:19 +0100 4692586 http://www.medworm.com/index.php?rid=4692585&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy371247q4433g715%2F Abstract  The aims of this study were to evaluate the effects of Photogem®-mediated photosensitization on rat palatal mucosa and the biodistribution of the photosensitizer in this tissue. A solution of Photogem® (500 or 1000 mg/l) was applied to the palatal mucosa for 30 min and the exposure time to blue LED (460 nm) was 20 min (144 J/cm2). At 0, 1, 3, and 7 days, palatal mucosa was photographed for macroscopic analysis. After killing, the palate was removed for microscopic analysis. Thermal mapping evaluated temperature change in the tissue during irradiation. All experimental groups revealed intact mucosa in the macroscopic analysis. Tissue alterations were observed microscopically for only four out of 80 animals subjected to PDT. Fluorescen... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4692585 Tue, 05 Apr 2011 16:58:19 +0100 4692585 http://www.medworm.com/index.php?rid=4683073&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fhn2355l715380531%2F This study is the first to compare the effectiveness of laser-induced thermotherapy and radiofrequency ablation of thyroid tissue. LITT as well as RFA are suitable for singular thyroid nodules and induces reproducible clinically relevant lesions in an appropriate application time. The maximum inducible lesion volumes by LITT are significantly larger than by RFA with the devices used herein. Content Type Journal ArticlePages 1-8DOI 10.1007/s10103-011-0907-0Authors Jörg-Peter Ritz, Department of General, Vascular and Thoracic Surgery, Charité – Universitätsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12200 Berlin, GermanyKai S. Lehmann, Department of General, Vascular and Thoracic Surgery, Charité – Universitätsmedizin Berlin, Campus Benjamin Franklin, Hind... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4683073 Fri, 01 Apr 2011 05:44:40 +0100 4683073 http://www.medworm.com/index.php?rid=4683074&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq314484400w17348%2F This study used a paired t test to determine the significance of blood flow recovery after treatment within each group while Independent t test compared results between the three groups. The level of significance was p < 0.05. The most frequently detected diabetes specific skin lesions were dryness, nail changes, hair loss, infections, itching, and frank eczema-like reactions, mostly in combinations (76%). This pattern appears specific for Egyptians as it is different from data registered in foreign literature. The minimum perfusion flow improved from 16.45 before LILT to 25.94 after, while maximum flow recovered from 32.91 to 48.47 and basal perfusion changed from 24.68 to 34.84 blood perfusion units. The percentage change in perfusion values was 23.17. All these were statistic... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4683074 Fri, 01 Apr 2011 05:44:39 +0100 4683074 http://www.medworm.com/index.php?rid=4669643&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg42gp1184u550v17%2F Abstract  Use of the CO2 laser (λ = 10.6 μm, continuous wave, defocused) is an established procedure for the treatment of premalignant lesions. Through employment of the sp-mode as well as scanners, thermal laser effects can be reduced but, on the other hand, a lesser degree of destruction of dysplastic cells could lead to an increased recurrence rate. The purpose of this study was to prospectively evaluate the recurrence rates resulting from different methods of CO2 laser vaporization. From May 1995 to May, 2005, 145 patients with a total of 148 premalignant lesions of the oral mucosa were treated in a prospective clinical study. Sixty-two lesions in 62 patients were vaporized with the defocused CO2 laser (group 1). In a further 45 lesions (43 patients, group 2), ... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4669643 Thu, 31 Mar 2011 07:20:09 +0100 4669643 http://www.medworm.com/index.php?rid=4630899&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl7306568556774h0%2F Abstract  Detection of demineralization of root surface caries is an important issue since preventive approaches prolong tooth life. Quantitative light-induced fluorescence (QLF) has been shown to be useful for the laboratory assessment of demineralization of root surfaces. The aim of this study was to determine the demineralization and remineralization of root surface intact and cavitated caries lesions using a QLF system as a nondestructive in vivo method. Noncavitated and demineralized root surface lesions were detected and scored using the QLF system. Oral hygiene education was given and periodontal cleaning was completed before the remineralization treatment. After obtaining baseline QLF data, the patients were informed about the remineralization treatment. Fluoride va... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4630899 Mon, 21 Mar 2011 19:07:28 +0100 4630899 http://www.medworm.com/index.php?rid=4580641&cid=s_33333_72_f&fid=33333&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh456003h51528742%2F Abstract  The aim of this trial was to investigate changes occurring in the subgingival microbiological composition of subjects with aggressive periodontitis, treated with antimicrobial photodynamic therapy (aPDT), in a single episode, or scaling and root planing (SRP), in a split-mouth design on −7, 0, and +90 days. Ten patients were randomly assigned to either aPDT using a laser source in conjunction with a photosensitizer or SRP with hand instruments. Subgingival plaque samples were collected and the counts of 40 subgingival species were determined using checkerboard DNA-DNA hybridization. The data were analyzed using the method of generalized estimating equations (GEE) to test the associations between treatments, evaluated parameters, and experimental times (α�... Lasers in Medical Science journals http://www.medworm.com/rss/comments.php?id=4580641 Fri, 11 Mar 2011 18:09:21 +0100 4580641