MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Malaria Journal' source. Wed, 08 Feb 2012 18:15:49 +0100 http://www.medworm.com/index.php?rid=5668189&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F36 Plasmodium knowlesi infection in humans along the southwestern border of Thailand, including interesting discussion on the possible changes in epidemiology. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5668189 Wed, 08 Feb 2012 05:00:00 +0100 5668189 http://www.medworm.com/index.php?rid=5668188&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F37 A paper which helps to understand how supply is organized from central to peripheral level, and how this might affect the supply of peripheral units. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5668188 Wed, 08 Feb 2012 05:00:00 +0100 5668188 http://www.medworm.com/index.php?rid=5668187&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F38 The paper adds to our knowledge of field-based, clinically oriented, NK cell subsets and cytokine production related to malarial innate immunity. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5668187 Wed, 08 Feb 2012 05:00:00 +0100 5668187 http://www.medworm.com/index.php?rid=5668190&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F35 An interesting study confirming that the parasite genetic complexity is lower in cerebral malaria than in patients with non-complicated malaria. In their study, the authors found that cerebral malaria patients harbour a parasite population dominated by a single variant identical throughout the blood and organs. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5668190 Tue, 07 Feb 2012 05:00:00 +0100 5668190 http://www.medworm.com/index.php?rid=5668191&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F34 Conclusions: There is a need to identify new compounds with activity against late stage gametocytes and the information provided by this in vitro assay is a valuable first step, which can guide future clinical studies. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5668191 Mon, 06 Feb 2012 05:00:00 +0100 5668191 http://www.medworm.com/index.php?rid=5660603&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F33 Another twist in the tale of cytoadherence ? Is in vitro cytoadherence really a marker of virulence, even in case of parasites, such as P. knowlesi or P. vivax, which are not normally sequestered ? (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5660603 Fri, 03 Feb 2012 05:00:00 +0100 5660603 http://www.medworm.com/index.php?rid=5649406&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F30 The paper describes histopathological changes induced by a murine malaria infection and relates this with hearing loss. It uses a well-stablished experimental model and addresses a major issue for malaria patients. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5649406 Wed, 01 Feb 2012 05:00:00 +0100 5649406 http://www.medworm.com/index.php?rid=5649405&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F31 This field study in the arid malaria-free oasis environment of Israel compares how the availability of a primary natural sugar source for mosquitoes - flowering Acacia trees - affects the efficacy of ATSB methods for mosquito control. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5649405 Wed, 01 Feb 2012 05:00:00 +0100 5649405 http://www.medworm.com/index.php?rid=5649404&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F32 Using data from a post-campaign survey, the authors investigated the effect of the mass distribution campaigns in achieving equity in household ownership and use ITNs (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5649404 Wed, 01 Feb 2012 05:00:00 +0100 5649404 http://www.medworm.com/index.php?rid=5649407&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F29 The pathogenesis of malaria is complex, and the clinical presentation of disease ranges from severe malaria, to mild and uncomplicated, to asymptomatic infections. Asymptomatic malaria remains a major challenge for malaria control programmes. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5649407 Tue, 31 Jan 2012 05:00:00 +0100 5649407 http://www.medworm.com/index.php?rid=5639172&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F27 The paper investigated associative learning in Anopheles gambiae in a laboratory bioassay using visual and olfactory cues. The results address an important knowledge gap in mosquito ecology and emphasize the role of associative memory for host finding and blood-feeding behaviour, with important potential implications for vector control. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5639172 Fri, 27 Jan 2012 05:00:00 +0100 5639172 http://www.medworm.com/index.php?rid=5639171&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F28 A new Thematic Series in Malaria Journal will, after each meeting of the Malaria Policy Advisory Committee (MPAC), a new WHO committee, publish its recommendations and the evidence to support them. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5639171 Fri, 27 Jan 2012 05:00:00 +0100 5639171 http://www.medworm.com/index.php?rid=5629992&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F26 This is a retrospective study of 519 cases of imported malaria, examining patterns and mechanisms of associated hyponatraemia. The results, which builds on work by the same authors published last year, is timely, because the issue of fluid resuscitation of patients with malaria controversial. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5629992 Thu, 26 Jan 2012 05:00:00 +0100 5629992 http://www.medworm.com/index.php?rid=5629993&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F25 Effect of different antimalarial treatments on haematologic parameters comparing artesunate-amodiaquine against various single treatment lines and combination therapies. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5629993 Wed, 25 Jan 2012 05:00:00 +0100 5629993 http://www.medworm.com/index.php?rid=5620957&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F24 The main finding here is that older mosquitoes are more susceptible to insecticides. This has important implications for understanding the epidemiological impact of resistance in field-based vector control interventions. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5620957 Mon, 23 Jan 2012 05:00:00 +0100 5620957 http://www.medworm.com/index.php?rid=5610439&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F23 Paper reporting the development of a TaqMan Real Time PCR assay for the detection of SNPs associated with anti-malarial resistance. This assay has promise as a convenient and efficient way to examine patient samples in resource-constrained settings. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5610439 Fri, 20 Jan 2012 05:00:00 +0100 5610439 http://www.medworm.com/index.php?rid=5610440&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F22 Paper describing a series of semi-automated protocols that will facilitate transfection of P. falciparum. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5610440 Wed, 18 Jan 2012 05:00:00 +0100 5610440 http://www.medworm.com/index.php?rid=5583571&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F21 This paper focuses on status of Integrated Vector Management in Uganda and is a good demonstration how surveys of individuals in different sectors can advance the development of IVM-based programmes in African countries. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5583571 Sat, 14 Jan 2012 05:00:00 +0100 5583571 http://www.medworm.com/index.php?rid=5583573&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F19 This paper provides an interesting descriptive review of nine years (eight malaria seasons) of routine malaria data from Mpumalanga Province, South Africa. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5583573 Fri, 13 Jan 2012 05:00:00 +0100 5583573 http://www.medworm.com/index.php?rid=5583572&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F20 Use of a pre-existing agent-based mathematical modelling platform for malaria to extend knowledge that is based on field studies on net and insecticide decay to model and estimate the epidemiological lifetimes of insecticide-treated bed nets under field conditions. A topic about which rather little is actually known. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5583572 Fri, 13 Jan 2012 05:00:00 +0100 5583572 http://www.medworm.com/index.php?rid=5583577&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F15 This study points to the importance of building malaria programmes, research and statistics that take into consideration the consequences of permanent impairment after a malaria attack, as well as the context of poverty in which they often occur. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5583577 Wed, 11 Jan 2012 05:00:00 +0100 5583577 http://www.medworm.com/index.php?rid=5583576&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F16 In this study, the distribution of pfcrt haplotypes and the pfmdr-1 mutation (N86Y) has been described across 11 sites in India and evaluated for a correlation between the prevalence of mutations and the clinical outcome of CQ treatment. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5583576 Wed, 11 Jan 2012 05:00:00 +0100 5583576 http://www.medworm.com/index.php?rid=5583575&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F17 The authors extend a previously published mathematical model to investigate the combined use of outdoor and indoor malaria vector control tools. These tools consist of a contact toxicant and a spatial repellent. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5583575 Wed, 11 Jan 2012 05:00:00 +0100 5583575 http://www.medworm.com/index.php?rid=5583574&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F18 The authors analysed the significance of distance and ITN possession/use through standard statistical tests. Strategies that exclusively distribute ITNs through health facilities are likely to be less effective in increasing possession and use in communities that are more distant from those facilities. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5583574 Wed, 11 Jan 2012 05:00:00 +0100 5583574 http://www.medworm.com/index.php?rid=5583579&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F13 The paper addresses the potential of statins in preventing experimental cerebral. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5583579 Tue, 10 Jan 2012 05:00:00 +0100 5583579 http://www.medworm.com/index.php?rid=5583578&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F14 With malaria elimination back on the global agenda, mapping of global and local P. vivax population structure is essential prior to establishing goals for elimination and the roll-out of interventions. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5583578 Tue, 10 Jan 2012 05:00:00 +0100 5583578 http://www.medworm.com/index.php?rid=5583580&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F12 There has recently been a renewed interested in Plasmodium vivax malaria.The publication of grey literature is useful and the manuscript brings to light data not previously accessible in the English language literature. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5583580 Mon, 09 Jan 2012 05:00:00 +0100 5583580 http://www.medworm.com/index.php?rid=5572838&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F8 As the coverage and use targets for ITNs move to ¿universal coverage¿, the role of community-level fostering of a ¿bed-net¿ culture will be an essential tool to reach those targets. The study design is robust and adds to the appeal of the study. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5572838 Fri, 06 Jan 2012 05:00:00 +0100 5572838 http://www.medworm.com/index.php?rid=5572839&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F7 Association of pfmdr1 polymorphisms with quinine reduced susceptibility. Polymorphisms in pfnhe-1 gene and copy numbers of pfmdr1 were not associated with decreased susceptibility to quinine. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5572839 Thu, 05 Jan 2012 05:00:00 +0100 5572839 http://www.medworm.com/index.php?rid=5561411&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F5 The authors investigate placenta volumes measured by 3D ultrasound technique in malaria affected pregnancies and in a control group. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5561411 Thu, 05 Jan 2012 05:00:00 +0100 5561411 http://www.medworm.com/index.php?rid=5561410&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F6 This report is the first to evaluate serum copeptin as a potential marker of infection severity in imported malaria. Copeptin was not superior to C-reactive protein in discriminating between severe and non-severe malaria infections in this study. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5561410 Thu, 05 Jan 2012 05:00:00 +0100 5561410 http://www.medworm.com/index.php?rid=5561414&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F2 The evidence on the efficacy of clindamycin plus quinine as an alternative treatment for uncomplicated malaria is inconclusive. Adequately powered trials are urgently required to compare this combination with artemisinin-based combinations. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5561414 Wed, 04 Jan 2012 05:00:00 +0100 5561414 http://www.medworm.com/index.php?rid=5561413&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F3 The aim of this study was to determine how the decision of female Anopheles gambiae to feed on sugar sources is influenced by the concurrent availability of resources, their body size and environmental variation. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5561413 Wed, 04 Jan 2012 05:00:00 +0100 5561413 http://www.medworm.com/index.php?rid=5561412&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F4 The Cambodian experience clearly demonstrated that a nationwide scale-up of community-based malaria control can be achieved without degrading community the quality of health workers¿ service. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5561412 Wed, 04 Jan 2012 05:00:00 +0100 5561412 http://www.medworm.com/index.php?rid=5561415&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F11%2F1%2F1 An interesting case study for future discussions of reimbursing malaria chemoprophylaxis for travellers to high risk areas. Only little data exist in the literature on the effect of chemoprophylaxis on treatment costs of imported malaria cases. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5561415 Mon, 02 Jan 2012 05:00:00 +0100 5561415 http://www.medworm.com/index.php?rid=5553097&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F388 An unusual contribution to the history of drug resistance in Africa: from collected blood slides from Japanese patients who had acquired malaria in Africa between 1984 and 1998, the authors extracted DNA and used PCR-based typing techniques to identify mutations associated with resistance to pyrimethamine and chloroquine. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5553097 Sat, 31 Dec 2011 05:00:00 +0100 5553097 http://www.medworm.com/index.php?rid=5553098&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F387 This is a report of a large study aimed to develop, implement and evaluate a strategy for the routine deployment of IPTi by the existing health services in Tanzania. The paper focuses on the impact of IPTi on mortality in children aged 2-11 months using the data from the cluster-randomized trial in 243,000 households. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5553098 Fri, 30 Dec 2011 05:00:00 +0100 5553098 http://www.medworm.com/index.php?rid=5553100&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F385 Evaluation of IPT for malaria in pregnant women using a cross-sectional design in antenatal clinics in Ghana, combined with qualitative assessment of perceptions of IPTp in the community. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5553100 Thu, 29 Dec 2011 05:00:00 +0100 5553100 http://www.medworm.com/index.php?rid=5553099&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F386 This paper explores the hypothesis that loss of Complement Regulatory Proteins on the surface of uninfected erythrocytes during falciparum malaria is associated with a decline in haemoglobin. The alternative hypothesis is that loss of CRP simply reflects the change in age distribution of erythrocytes in acute malarial anaemia. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5553099 Thu, 29 Dec 2011 05:00:00 +0100 5553099 http://www.medworm.com/index.php?rid=5538844&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F383 This retrospective study reports the prognostic significance of plasma Ang-1 and Ang-2 in falciparum malaria in a group of Indian patients. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5538844 Fri, 23 Dec 2011 05:00:00 +0100 5538844 http://www.medworm.com/index.php?rid=5538843&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F384 Analysis of healthy, malaria-infected, and non-malarious febrile patients: spectra of urine samples were collected and traditional multivariate tools were used to classify samples and ¿identify¿ putative biomarkers. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5538843 Fri, 23 Dec 2011 05:00:00 +0100 5538843 http://www.medworm.com/index.php?rid=5526332&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F381 Albeit the usefulness (and limitations) of spleen rate and parasite rates as malaria metrics is already covered by an abundant literature, this study is presented as standard surveillance data that could be helpful to local health authorities. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5526332 Wed, 21 Dec 2011 05:00:00 +0100 5526332 http://www.medworm.com/index.php?rid=5526331&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F382 The authors investigated the possibility that susceptibility of Anopheles gambiae to malaria is associated with the environment experienced by its mother. Two maternal environmental factors food quality and microsporidian infection were used as maternal stressors, and their implications on susceptibility of the next generation Plasmodium was investigated. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5526331 Wed, 21 Dec 2011 05:00:00 +0100 5526331 http://www.medworm.com/index.php?rid=5526336&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F377 Large-scale assessment of the effect of malaria diagnostics on the probability of receiving antibiotics in a Ugandan population living in an area of unstable malaria transmission. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5526336 Tue, 20 Dec 2011 05:00:00 +0100 5526336 http://www.medworm.com/index.php?rid=5526335&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F378 The paper represents a Herculean effort to provide an updated map of the global distribution of malaria, based on three key malariometric indices PfPR, PfEIR and PfRC and represents a unique contribution. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5526335 Tue, 20 Dec 2011 05:00:00 +0100 5526335 http://www.medworm.com/index.php?rid=5526334&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F379 A case study proposing a framework for evaluating the performance of malaria control strategies. The malaria control strategies (indoor spraying, ITNs, diagnosis, and treatment) of five Latin American countries (Bolivia, Colombia, Guyana, Equador, Peru) are assessed on the adequacy level with information and data from national health officials and PAHO reports. Results show heterogeneity with respect to the adequate implementation of control measures within and between the countries. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5526334 Tue, 20 Dec 2011 05:00:00 +0100 5526334 http://www.medworm.com/index.php?rid=5526333&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F380 This study closely followed malaria parasite dynamics in Tanzanian children before and after therapy, with genotyping of parasites collected at 11 different time points affording a comprehensive look at genotype complexity.The report adds importantly to our understanding of parasite dynamics during therapy, and in particular to the limitations of current genotyping methodology for the classification of treatment outcomes. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5526333 Tue, 20 Dec 2011 05:00:00 +0100 5526333 http://www.medworm.com/index.php?rid=5526338&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F375 A paper demonstrating that burning plants releases repellent volatiles that are repellent to mosquitoes. It also introduces a slight modification to the membrane method of testing mosquito repellents, which should be further pursued. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5526338 Mon, 19 Dec 2011 05:00:00 +0100 5526338 http://www.medworm.com/index.php?rid=5526337&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F376 The paper describes a comprehensive study of the loci associated with chloroquine and sulphadoxine-pyrimethamine resistance in P. falciparum and P. vivax in Honduras. Mesoamerica is one of the few places in the world where these two drugs are still the first-line therapy for both parasites. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5526337 Mon, 19 Dec 2011 05:00:00 +0100 5526337 http://www.medworm.com/index.php?rid=5516096&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F372 RDT was cost effective in both low and high transmission settings. This confirms that in a Malaria Control Programme, the stakeholders need a strategy for malaria diagnosis, because of the risk that presumptive treatment may always seem more attractive. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5516096 Mon, 19 Dec 2011 05:00:00 +0100 5516096 http://www.medworm.com/index.php?rid=5516095&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F373 In Uganda, parasite-based diagnosis is recommended for every patient suspected to have malaria before prescribing anti-malarials. The study showed that it was more feasible to implement parasite-based diagnosis for malaria using RDT than with microscopy, but a high proportion of patients with negative results were still prescribed anti-malarials. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5516095 Mon, 19 Dec 2011 05:00:00 +0100 5516095 http://www.medworm.com/index.php?rid=5516097&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F371 Paper measures genetic diversity among natural parasite populations of Plasmodium falciparum from Lao PDR. The report is relevant as it may help understand local parasite population structure and transmission dynamics, and provides important data for future vaccine and drug deployment. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5516097 Sat, 17 Dec 2011 05:00:00 +0100 5516097 http://www.medworm.com/index.php?rid=5506212&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F369 The study investigates the impact of different weight bands on treatment outcome after AL treatment. There has been some concern that the dosing optimization according weight bands may result in over dosing young children and under dosing older children. Therefore this study and the findings are very important for malaria endemic countries that have adopted AL as the first-line regimen. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5506212 Fri, 16 Dec 2011 05:00:00 +0100 5506212 http://www.medworm.com/index.php?rid=5506214&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F367 A study linking observed household infection status to a series of individual and household level covariates. The results are likely to be of regional interest. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5506214 Thu, 15 Dec 2011 05:00:00 +0100 5506214 http://www.medworm.com/index.php?rid=5506213&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F368 Although the sample size is small, the results indicate difference in the prevalence and distribution of G6PD gene variants among the Thai and Burmese populations in different malaria endemic areas. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5506213 Thu, 15 Dec 2011 05:00:00 +0100 5506213 http://www.medworm.com/index.php?rid=5506216&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F365 Paper addressing a very important problem within the policy of using ACT treating uncomplicated falciparum malaria in African children. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5506216 Wed, 14 Dec 2011 05:00:00 +0100 5506216 http://www.medworm.com/index.php?rid=5506215&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F366 Report on the association of 6 SNPs in the ADAMTS13 gene and the risk of cerebral malaria. There is indeed increasing evidence that an imbalance in plasma levels and activity of von Willebrand factor and ADAMTS13 may contribute to the malaria-associated thrombocytopaenia and possibly the pathogenesis of severe disease. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5506215 Wed, 14 Dec 2011 05:00:00 +0100 5506215 http://www.medworm.com/index.php?rid=5506221&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F357 Success of any bed-net programme depends on two key issues, community acceptability of nets and compliance to use. In this context, the present manuscript assumes importance as it has clearly summarized the results of the study that assessed the progress in the possession of nets by the community and their preferential use. The outcome of the study has practical implication on malaria control. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5506221 Tue, 13 Dec 2011 05:00:00 +0100 5506221 http://www.medworm.com/index.php?rid=5506220&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F359 The paper reports results of immunogenicity studies with GMZ2 formulated with various adjuvants in different mouse strains.Since vaccines with virosomal formulations are already commercial available and display a good safety profile a malaria vaccine formulated with virosomes may be developed fast if they prove to be better. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5506220 Tue, 13 Dec 2011 05:00:00 +0100 5506220 http://www.medworm.com/index.php?rid=5506219&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F360 This paper reports the findings for a study carried out in India in 2008 which aimed to document the availability of and prescription practices with regards anti-malarial drugs and in particular artemisinin monotherapy. This is an important topic given India¿s geographically strategic location, lying between the epicentre of artemisinin resistance on the Thai-Cambodia border to the East ¿ and the continent of Africa to the West. The key finding are very concerning and it is reassuring that some action has apparently taken place since the study took place. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5506219 Tue, 13 Dec 2011 05:00:00 +0100 5506219 http://www.medworm.com/index.php?rid=5506218&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F361 A well-conducted study which shows an interesting way to map the malaria transmission risk area using spatial technologies, such as remote sensing, GPS and GIS. This is the way to go for improving information and knowledge on malaria vectors and for implementing more efficient and targeted vector control. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5506218 Tue, 13 Dec 2011 05:00:00 +0100 5506218 http://www.medworm.com/index.php?rid=5506217&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F362 The authors address an important question in malaria immunology, namely do the immune parameters of infants differ among those living in the areas of malaria-endemic transmission versus malaria unstable transmission. The parameters the authors chose to measure are B and T cell subsets in peripheral blood and serum Ig levels. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5506217 Tue, 13 Dec 2011 05:00:00 +0100 5506217 http://www.medworm.com/index.php?rid=5495596&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F352 Criminals are producing diverse harmful anti-malarial counterfeits with important public health consequences. With the threatening spread of artemisinin resistance to Africa, much greater investment is required to ensure the quality of ACT and removal of artemisinin monotherapies. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5495596 Tue, 13 Dec 2011 05:00:00 +0100 5495596 http://www.medworm.com/index.php?rid=5495597&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F351 Paper reviews the published literature on the use of primaquine as an agent for prophylaxis and radical cure. The detailed section on G6PD deficiency as a barrier for mass administration of primaquine and the section on the use of primaquine with blood schizontocidals other than chloroquine is useful. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5495597 Mon, 12 Dec 2011 05:00:00 +0100 5495597 http://www.medworm.com/index.php?rid=5488015&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F350 Paper summarizes the use of the transgenic P. berghei parasite expressing luciferase (PbGFP-Luc) for the analysis of sporozoite induced immunity in vivo and in vitro. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5488015 Fri, 09 Dec 2011 05:00:00 +0100 5488015 http://www.medworm.com/index.php?rid=5477495&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F349 An interesting study of how artemether-lumefantrine is used in practice in Ethiopia. It highlights that adherence to treatment is a major concern, something that may not be fully appreciated by all practitioners. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5477495 Mon, 05 Dec 2011 05:00:00 +0100 5477495 http://www.medworm.com/index.php?rid=5469891&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F348 Report of a compound that could be used to inhibit or reverse infected red blood cell binding to the host receptor, ICAM-1. This manuscript is focused on a very narrow question whether the compound (+)-epigallocatechin (EGCG) can inhibit binding of different ICAM-1 binding parasite isolates. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5469891 Thu, 01 Dec 2011 05:00:00 +0100 5469891 http://www.medworm.com/index.php?rid=5450121&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F346 Surprisingly, while Plasmodium falciparum has been grown in vitro for many years, other malaria parasites have always proven much more difficult to adapt. Optimization of the in vitro culture conditions for P. berghei parasites is likely open up the field. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5450121 Fri, 25 Nov 2011 05:00:00 +0100 5450121 http://www.medworm.com/index.php?rid=5450120&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F347 Imported malaria cases among children and adolescents in Barcelona over a period of 18 years, analysing demographic and clinical aspects, as well as the development of the incidence during the study period. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5450120 Fri, 25 Nov 2011 05:00:00 +0100 5450120 http://www.medworm.com/index.php?rid=5442280&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F345 Although several papers have addressed the accuracy of pLDH-based rapid tests, this paper also deals with the important issue of the potential use of RDTs for treatment follow-up. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5442280 Thu, 24 Nov 2011 05:00:00 +0100 5442280 http://www.medworm.com/index.php?rid=5442281&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F344 The paper outlines the importance of qualitative research in understanding community programmes. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5442281 Wed, 23 Nov 2011 05:00:00 +0100 5442281 http://www.medworm.com/index.php?rid=5409746&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F343 A very relevant paper given the prevailing malaria vector control landscape where there are emerging reports of pyrethroid insecticide resistance among malaria vectors across Africa at a rate never experienced before. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5409746 Wed, 16 Nov 2011 05:00:00 +0100 5409746 http://www.medworm.com/index.php?rid=5409747&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F342 The authors recommend that the WHO recommendation for the routine insertion of a central venous catheter, and the maintenance of a central venous pressure of 0-5 cmH2O in adults with severe malaria, should be reconsidered. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5409747 Mon, 14 Nov 2011 05:00:00 +0100 5409747 http://www.medworm.com/index.php?rid=5409748&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F341 ITN delivery through routine health services, such as antenatal care (ANC) and childhood vaccination (EPI), is a promising channel of delivery to reach individuals with the highest risk (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5409748 Sun, 13 Nov 2011 05:00:00 +0100 5409748 http://www.medworm.com/index.php?rid=5401437&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F339 The paper presents a new tool to estimate the parasite clearance rate of Plasmodium falciparum in subjects under treatment with an artemisinin-based combination. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5401437 Thu, 10 Nov 2011 05:00:00 +0100 5401437 http://www.medworm.com/index.php?rid=5401436&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F340 A nationwide survey of laboratories in the United States and its nine dependent territories was conducted in 2010 to determine factors that may contribute to shortcomings in the diagnosis of malaria. Although malaria diagnostic testing services were available to a majority of U.S. laboratories surveyed, very few were in complete compliance with all of the CLSI guidelines for analysis and reporting of results, and most respondents reported very few cases of malaria annually. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5401436 Thu, 10 Nov 2011 05:00:00 +0100 5401436 http://www.medworm.com/index.php?rid=5389024&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F338 Despite its enormous historical successes, mosquito larval source management (LSM) remains a largely forgotten and often dismissed intervention for malaria control in Africa, in large part because of the perceived cost of such interventions. The paper shows that costs for LSM compare favourably with costs for IRS and LLINs, especially in areas with moderate and focal malaria transmission where mosquito larval habitats are accessible and well defined. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5389024 Tue, 08 Nov 2011 05:00:00 +0100 5389024 http://www.medworm.com/index.php?rid=5389028&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F334 A study that has the potential to add to our knowledge of the cognitive and behavioral impairments associated with malaria with neurological impairment in particularly by extending the range of outcomes that have been assessed in this population. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5389028 Thu, 03 Nov 2011 04:00:00 +0100 5389028 http://www.medworm.com/index.php?rid=5389027&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F335 Study on malaria pharmaceutical practices in six Brazilian municipalities with high malaria incidence. The topic of pharmaceutical assistance for malaria in Latin America is of major public health importance and has not received the deserved attention in the literature and the results of this study may have important consequences for malaria-oriented health services in the Amazon region and may contribute to the adoption of more effective organizational strategies. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5389027 Thu, 03 Nov 2011 04:00:00 +0100 5389027 http://www.medworm.com/index.php?rid=5389026&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F336 The paper further documents the susceptibility of individuals previously considered to be resistant to P. vivax infection and disease. Moreover, with previous reports, their findings in Mauritania now illustrate that the capacity of P. vivax to infect Duffy-negatives spans from coastal western Africa to eastern African study locations in Kenya and in Madagascar. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5389026 Thu, 03 Nov 2011 04:00:00 +0100 5389026 http://www.medworm.com/index.php?rid=5389025&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F337 This paper covers a systematic review on the costs and cost-effectiveness of malaria control interventions. The interventions covered include insecticide-treated bed nets Indoor residual spraying and Intermittent preventative treatment, diagnostic testing and appropriate treatment. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5389025 Thu, 03 Nov 2011 04:00:00 +0100 5389025 http://www.medworm.com/index.php?rid=5389032&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F330 Interesting contribution to our knowledge of the pathophysiology of severe malaria in the ANKA model - characterization of metabolites in pleural effusion formed during murine cerebral malaria (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5389032 Wed, 02 Nov 2011 04:00:00 +0100 5389032 http://www.medworm.com/index.php?rid=5389031&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F331 Important issue for in-vitro diagnostics (and many other medical practices and procedures): do the symbols created by the manufacturer or others to convey essential information successfully convey that information to people who will be preparing the tests or carrying out the procedures? (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5389031 Wed, 02 Nov 2011 04:00:00 +0100 5389031 http://www.medworm.com/index.php?rid=5389030&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F332 There is a general awareness that quality is generally exceedingly poor in African malarious areas and that microscopy is not as an effective aid to clinical decision as it could be. Having fresh data on microscopy quality in the field is remarkably useful. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5389030 Wed, 02 Nov 2011 04:00:00 +0100 5389030 http://www.medworm.com/index.php?rid=5389029&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F333 The study is a useful for Cameroon and other malaria control programmes on how to make judicious choice of the best candidate to be used for IRS. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5389029 Wed, 02 Nov 2011 04:00:00 +0100 5389029 http://www.medworm.com/index.php?rid=5362864&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F324 The paper raises an interesting question which has relevance to current efforts to eliminate and control malaria, namely whether risk factors for malaria vary over the time. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5362864 Mon, 31 Oct 2011 04:00:00 +0100 5362864 http://www.medworm.com/index.php?rid=5362863&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F325 This is a methodological paper that describes how the ACTwatch project is implemented and the design of the three components, supply chain research, outlet surveys and household surveys. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5362863 Mon, 31 Oct 2011 04:00:00 +0100 5362863 http://www.medworm.com/index.php?rid=5362862&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F326 Useful synthesis of survey results providing essential information on the availability of anti-malarials, especially in the private sector where data has been extremely limited. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5362862 Mon, 31 Oct 2011 04:00:00 +0100 5362862 http://www.medworm.com/index.php?rid=5362861&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F327 The household surveys conducted by ACTwatch are rich resources of information on case management and this synthesis of the data adds to our knowledge of care-seeking, diagnostics and treatment of sick children. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5362861 Mon, 31 Oct 2011 04:00:00 +0100 5362861 http://www.medworm.com/index.php?rid=5362860&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F328 An interesting paper, reporting data from large surveys both at outlet and household level. While this data shows favourable progress towards replacing artemisinin monotherapies with ACT, the widespread use of drug cocktails to treat malaria is a barrier to effective case management. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5362860 Mon, 31 Oct 2011 04:00:00 +0100 5362860 http://www.medworm.com/index.php?rid=5362859&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F329 A hypothesis that sexual recombination is important to determine the local subpopulation structure, based on the analysis of a longitudinal dataset. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5362859 Mon, 31 Oct 2011 04:00:00 +0100 5362859 http://www.medworm.com/index.php?rid=5362867&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F321 A thorough review of malaria diagnostic comparisons for the detection of malaria in pregnancy. The paper demonstrates that most of the available information is from Africa and involves the detection of P. falciparum, while our knowledge of issues outside Africa and for the detection of non-falciparum species are very limited. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5362867 Fri, 28 Oct 2011 04:00:00 +0100 5362867 http://www.medworm.com/index.php?rid=5362866&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F322 Introducing an intervention with system-wide effect, such as the use of RDTs in areas where malaria is still a public health problem, should be accompanied by system strengthening measures to better attain the goal of improving quality of care. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5362866 Fri, 28 Oct 2011 04:00:00 +0100 5362866 http://www.medworm.com/index.php?rid=5362865&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F323 The sensitivity of a given PCR assay varies between laboratories. The optimal approach to standardize methodologies is to provide PCR template standards. These will help researchers in different settings to ensure that the nucleic acid amplification protocols they wish to use provide the requisite level of sensitivity, and will permit comparison between sites. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5362865 Fri, 28 Oct 2011 04:00:00 +0100 5362865 http://www.medworm.com/index.php?rid=5362868&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F319 A baseline survey of malaria-related issues in the south-eastern areas of Iran, including Sistan & Baluchestan, Hormozgan and the tropical part of Kerman provinces, which account for around 95% of all malaria cases in the country (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5362868 Thu, 27 Oct 2011 04:00:00 +0100 5362868 http://www.medworm.com/index.php?rid=5349166&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F316 This paper addresses a timely and extremely relevant topic for improving access to effective malaria medicines through an ambitious yet experimental subsidy scheme intervention‐the Affordable Medicine Facility‐malaria (AMFm) pilot in one of the country in sub‐Saharan Africa. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5349166 Wed, 26 Oct 2011 04:00:00 +0100 5349166 http://www.medworm.com/index.php?rid=5349165&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F317 One of the findings of the study is the protective role ACT can have in slowing down the rate of drug resistance: here, the adoption of ACT slowed the rate of increase in the frequency of the triple mutant resistant dhfr allele. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5349165 Wed, 26 Oct 2011 04:00:00 +0100 5349165 http://www.medworm.com/index.php?rid=5349164&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F318 The paper describes the characterization of a mitochondrial malic enzyme from A. stephensi. The authors identified the enzyme in the mitochondrial fraction from cultured mosquito cells via LC/MS.MS analysis. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5349164 Wed, 26 Oct 2011 04:00:00 +0100 5349164 http://www.medworm.com/index.php?rid=5349167&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F315 Elegant methodology enabling the absolute quantification of pre-selected plasmodial proteins using a combined QconCAT SRM-MS approach. The novel method would clearly offer a direct route to quantifying potentially any protein in this most difficult of proteomes. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5349167 Tue, 25 Oct 2011 04:00:00 +0100 5349167 http://www.medworm.com/index.php?rid=5349168&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F314 Conclusions: This study shows the identification and characterization of the P. vivax rhoptry neck protein-1 in the VCG-1 strain. Taking into account that PvRON1 shares several important characteristics with other Plasmodium antigens that play a functional role during RBC invasion and, as shown here, it is antigenic, it could be considered as a good vaccine candidate. Further studies aimed at assessing its immunogenicity and protection-inducing ability in the Aotus monkey model are thus recommended. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5349168 Mon, 24 Oct 2011 04:00:00 +0100 5349168 http://www.medworm.com/index.php?rid=5337405&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F311 Responsiveness of the NK cell line NK92 to P. falciparum parasitized red blood cells. Under the experimental conditions used, NK92 cells were unable to secrete IFN-gamma or to upregulate the expression of activation markers upon parasite stimulation. Changes in transcriptional profiles were detected in NK92 cells after contact with the parasite. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5337405 Fri, 21 Oct 2011 04:00:00 +0100 5337405 http://www.medworm.com/index.php?rid=5337404&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F312 This study examines the determinants of malaria transmission in Dakar and is important given the emerging problem of malaria in urban environments. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5337404 Fri, 21 Oct 2011 04:00:00 +0100 5337404 http://www.medworm.com/index.php?rid=5337403&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F313 A valuable case study that needs to be evaluated in detail in order to better understand malaria elimination and control. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5337403 Fri, 21 Oct 2011 04:00:00 +0100 5337403 http://www.medworm.com/index.php?rid=5337406&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F310 The paper describes a steep reduction in the prevalence of chloroquine resistant parasites and an increase in the prevalence of mefloquine resistant parasites in the Dakar region. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5337406 Thu, 20 Oct 2011 04:00:00 +0100 5337406 http://www.medworm.com/index.php?rid=5337407&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F309 Results of the study indicate that blood group ¿O¿ is associated with reduced and ¿B¿ blood group with increased risk of development of severe malaria in Odisha, India. Meta-analysis also supports the protective nature of blood group ¿O¿ from severe falciparum infection. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5337407 Wed, 19 Oct 2011 04:00:00 +0100 5337407 http://www.medworm.com/index.php?rid=5324743&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F306 Hospital-based operational study comparing the accuracy of an HRP-2 specific rapid diagnostic test (RDT) to Giemsa light microscopy in the diagnosis of falciparum malaria in a hyper-endemic setting. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5324743 Tue, 18 Oct 2011 04:00:00 +0100 5324743 http://www.medworm.com/index.php?rid=5324742&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F307 Conclusions: Bioassay experiments indicated that incorporating insecticides into a conventional paint binder or adsorbing them onto phosphogypsum can provide for extended effective life spans that compare favourably with DDT's performance under accelerated ageing conditions. Best results were obtained with propoxur in standard acrylic emulsion paint. Similarly, insecticides adsorbed on phosphogypsum and sprayed on cattle manure coated surfaces provided superior lifespans compared with DDT sprayed directly on a similar surface. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5324742 Tue, 18 Oct 2011 04:00:00 +0100 5324742 http://www.medworm.com/index.php?rid=5324741&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F308 This study reports the findings of an external quality assessment (EQA) showing an alternative to cross-checking of blood slides in the quality control of malaria microscopy. The present EQA revealed a poor quality of malaria microscopy the Democratic Republic of the Congo (DRC). (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5324741 Tue, 18 Oct 2011 04:00:00 +0100 5324741 http://www.medworm.com/index.php?rid=5324746&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F303 This paper presents a new mathematical model describing the mosquito life-cycle and ecology. The model is fairly detailed and comprehensive, and similar in its intent and scope to the Depinay model. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5324746 Mon, 17 Oct 2011 04:00:00 +0100 5324746 http://www.medworm.com/index.php?rid=5324745&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F304 A longitudinal analysis of the haplotypes of P. falciparum isolates collected before and after the replacement of chloroquine with AQ/AS in Gabon. The authors document the very strong retention of the CQ-resistant alleles of Pfcrt even after the withdrawal of chloroquine in 2003. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5324745 Mon, 17 Oct 2011 04:00:00 +0100 5324745 http://www.medworm.com/index.php?rid=5324744&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F305 The findings in this paper focus on two topics: (i) the cost-effectiveness of IPTi at averting anaemia and (ii) the influence of using according to protocol trial analysis as the measure of effect, as opposed to the more commonly used intention to treat. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5324744 Mon, 17 Oct 2011 04:00:00 +0100 5324744 http://www.medworm.com/index.php?rid=5316474&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F300 Assessment of HRP-2 and aldolase co-reactivity can be of help in clinical decision making in the acute care setting of returning travellers suspected of having malaria. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5316474 Fri, 14 Oct 2011 04:00:00 +0100 5316474 http://www.medworm.com/index.php?rid=5316473&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F301 Elucidation of the relationships between malaria incidence and climatic and non-climatic factors in a region is essential for understanding the causative factors of disease dissemination and design of control strategies. The methodology described promises to provide reliable forecast of malaria incidence across varying environmental conditions (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5316473 Fri, 14 Oct 2011 04:00:00 +0100 5316473 http://www.medworm.com/index.php?rid=5316472&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F302 The article suggests that the changing symptomatology, reduced capacity of technicians and failure to inform the relevant authorities can lead to setbacks in the malaria elimination process. Further, it highlights the possible role of clinicians in the pre-elimination phase of malaria in Sri Lanka. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5316472 Fri, 14 Oct 2011 04:00:00 +0100 5316472 http://www.medworm.com/index.php?rid=5316475&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F299 The paper describes an assessment of net effectiveness after three years of field use. It includes important data and observations, especially on the aspect physical durability and to a lesser degree on bio-efficacy. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5316475 Thu, 13 Oct 2011 04:00:00 +0100 5316475 http://www.medworm.com/index.php?rid=5305317&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F295 Paper investigates the anti-plasmodial effect of the South African medicinal plant Dicoma anomala subsp. gerrardii, based on its ethnomedicinal profile. Using conventional fractionation and purification techniques, authors were able by various chemical techniques to identify the most active anti-plasmodial compound in the in vitro P. falciparum as dehydrobrachylaenolide, a sesquiterpene lactone. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5305317 Tue, 11 Oct 2011 04:00:00 +0100 5305317 http://www.medworm.com/index.php?rid=5305316&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F296 The paper explores the changes in parasite rates and ITN use in young children in eight purposively selected villages in Burkina Faso over a period of ten years. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5305316 Tue, 11 Oct 2011 04:00:00 +0100 5305316 http://www.medworm.com/index.php?rid=5305315&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F297 A review describing current and, more importantly, past (and forgotten) understanding of the biology of relapse in P. vivax malaria. It provides a welcome treasure trove of citations to that older literature, in addition to putting forth an interesting new hypothesis worthy of testing, i.e., activation of hypnozoites by febrile illness. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5305315 Tue, 11 Oct 2011 04:00:00 +0100 5305315 http://www.medworm.com/index.php?rid=5305314&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F298 Co-distribution of LF and malaria parasites, using survey data collected in the same individuals (school aged children) at the same time (national survey conducted between 2000-2003) in Uganda. These are important pathogens, transmitted by the same vector and, given the potential for integrated control, investigation of factors driving co-endemicity are timely. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5305314 Tue, 11 Oct 2011 04:00:00 +0100 5305314 http://www.medworm.com/index.php?rid=5305319&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F293 Lumefantrine displayed similar pharmacokinetics in the rat as in humans, with multiphasic disposition, low clearance, and a large volume of distribution resulting in a long terminal elimination half-life. The absolute oral bioavailability of lumefantrine was found to be dose dependent. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5305319 Mon, 10 Oct 2011 04:00:00 +0100 5305319 http://www.medworm.com/index.php?rid=5305318&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F294 A mosquito population model is proposed to evaluate the sensitivity of An. gambiae s.s. population to some peculiar thermal-pluviometric scenarios. The scenarios are obtained from four Kenyan sites (Nairobi, Nyabondo, Kibwesi, and Malindi) representing four different eco-epidemiological settings. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5305318 Mon, 10 Oct 2011 04:00:00 +0100 5305318 http://www.medworm.com/index.php?rid=5297827&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F291 In this study, transgenic P. falciparum and P. berghei lines stably expressing PvDHFR-TS were obtained. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5297827 Fri, 07 Oct 2011 04:00:00 +0100 5297827 http://www.medworm.com/index.php?rid=5297826&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F292 This paper covers an interesting and important topic: an overview of available material on the use of mefloquine in children, including some data from reports that were previously submitted to regulatory authorities, but which were otherwise not available in the public domain. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5297826 Fri, 07 Oct 2011 04:00:00 +0100 5297826 http://www.medworm.com/index.php?rid=5297828&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F290 Use of RDTs to direct the use of anti-malarial drugs in young children did not result in any missed diagnoses of malaria although new infections soon after a consultation with a negative RDT result may undermine confidence in results. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5297828 Thu, 06 Oct 2011 04:00:00 +0100 5297828 http://www.medworm.com/index.php?rid=5286813&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F289 Paper reports evidence of high genetic differentiation among An. arabiensis populations from Kilombero valley in Tanzania. This subject is very relevant and original, as very few indications of population sub-structuring have been reported in this malaria vector species. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5286813 Wed, 05 Oct 2011 04:00:00 +0100 5286813 http://www.medworm.com/index.php?rid=5286814&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F288 Paper sheds light on fundamental issues, such as inequality in health and the value of health promotion and education, particularly among the poorer segments of the population. Such knowledge may change behaviour and lead to an increased utilization of LLINs. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5286814 Tue, 04 Oct 2011 04:00:00 +0100 5286814 http://www.medworm.com/index.php?rid=5274983&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F287 An important paper on the malaria vectors of the Santa Isabel Province, Solomon Islands, which gives the current status of the vectorial fauna and valuable insights into vector control and the perspective of malaria elimination from this area of Southwest Pacific. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5274983 Fri, 30 Sep 2011 04:00:00 +0100 5274983 http://www.medworm.com/index.php?rid=5274985&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F285 The paper describes a retrospective study of hospital records of children aged 2months to 13 years seen at a hospital in Senegal in 2004 and 2005. Data are presented for treatments given to febrile, non-febrile, tested, untested patients and patients with unknown temperature. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5274985 Thu, 29 Sep 2011 04:00:00 +0100 5274985 http://www.medworm.com/index.php?rid=5274984&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F286 These results suggest that false-negative malaria RDT results will rarely occur due to a prozone-like effect in high-density infections, and other causes are more likely. RDT line intensity is poorly indicative of parasite density in high-density infections and RDTs should, therefore, not be considered quantitative. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5274984 Thu, 29 Sep 2011 04:00:00 +0100 5274984 http://www.medworm.com/index.php?rid=5261932&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F283 Parasites bearing Pfdhfr I164L single mutation were found in Madagascar. These new mutants may challenge the use of antifolates for the intermittent preventive treatment of malaria during pregnancy. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5261932 Tue, 27 Sep 2011 04:00:00 +0100 5261932 http://www.medworm.com/index.php?rid=5261931&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F284 Paper describing a pLDH-based test which has appears to be superior to previous pLDH RDTs. The very high sensitivity for both P. falciparum and P. vivax is particularly encouraging. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5261931 Tue, 27 Sep 2011 04:00:00 +0100 5261931 http://www.medworm.com/index.php?rid=5251633&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F282 Monitoring P. vivax resistance to anti-malarial drugs in vivo and in vitro remaind challenging, but some molecular markers of resistance can be used in surveillance studies. A new high-throughput assay relevant markers of drug resistance was developed and assessed on Papua New Guinea patient isolates. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5251633 Sat, 24 Sep 2011 04:00:00 +0100 5251633 http://www.medworm.com/index.php?rid=5251634&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F281 In the perspective of the present deployment of ACT in Africa and the risk of emergence of resistance to these combinations, the paper addresses the important topic of how to influence adherence to treatment. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5251634 Fri, 23 Sep 2011 04:00:00 +0100 5251634 http://www.medworm.com/index.php?rid=5251635&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F280 A cohort study in Tanzania in which the incidence of malaria was compared between individuals with and without alpha thalassaemia. Thalassaemics had more episodes in the first year of life, but then had fewer episodes than non thalassaemics after this. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5251635 Thu, 22 Sep 2011 04:00:00 +0100 5251635 http://www.medworm.com/index.php?rid=5239178&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F276 A descriptive study of genotyping patterns of P falciparum in isolates from Brazaville. The paper is informative considering the few papers published on molecular epidemiology in this area. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5239178 Thu, 22 Sep 2011 04:00:00 +0100 5239178 http://www.medworm.com/index.php?rid=5239177&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F277 Data were collected in a cluster randomized cross-sectional survey from 5,466 households in both rural and urban areas of 20 malaria-affected districts of Iran. The study indicates that low access along with low understanding of the role of nets in malaria prevention are the main barriers to utilization of bed nets. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5239177 Thu, 22 Sep 2011 04:00:00 +0100 5239177 http://www.medworm.com/index.php?rid=5239176&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F278 The author presents a clear and concise introduction to the parasite clearance curve, which is important in determining the therapeutic response to anti-malarials, particularly artemisinin derivatives. Given the recent reports of emerging artemisinin resistance in Western Cambodia, this is a very timely report. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5239176 Thu, 22 Sep 2011 04:00:00 +0100 5239176 http://www.medworm.com/index.php?rid=5239175&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F279 A survey of ACT knowledge conducted among health care providers in Malawi. Most of the participants have not received any training on how to use ACT and how to report adverse effects arising from the use of ACT. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5239175 Thu, 22 Sep 2011 04:00:00 +0100 5239175 http://www.medworm.com/index.php?rid=5239179&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F275 A succinct and well-written study on the pharmacokinetic interactions of amodiaquine and artesunate on sulphadoxine/pyrimethamine. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5239179 Wed, 21 Sep 2011 04:00:00 +0100 5239179 http://www.medworm.com/index.php?rid=5239181&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F273 This paper analyses the costs of intermittent screening and treatment (IST) of malaria in schools on the Kenyan coast.In the current context, IST is a relatively expensive school-based malaria intervention, but costs can be reduced by simplifying the protocole. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5239181 Tue, 20 Sep 2011 04:00:00 +0100 5239181 http://www.medworm.com/index.php?rid=5239180&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F274 The gradient metric modelling approach and electron-density molecular representation can be powerful tools in the discovery and design of novel anti-malarial compounds. The technology can be used for de novo design of small molecules with activity against not only the asexual phase, but also against the liver stage of the parasite. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5239180 Tue, 20 Sep 2011 04:00:00 +0100 5239180 http://www.medworm.com/index.php?rid=5239184&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F270 This study describes comparative efficiency of three mosquito sampling techniques; HLC, CDC-LT and IRS for sampling malaria vectors in two villages in Senegal. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5239184 Mon, 19 Sep 2011 04:00:00 +0100 5239184 http://www.medworm.com/index.php?rid=5239183&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F271 This review describes and discusses human gene polymorphisms identified thus far that have been shown to be associated with susceptibility or resistance to P. falciparum malaria. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5239183 Mon, 19 Sep 2011 04:00:00 +0100 5239183 http://www.medworm.com/index.php?rid=5239182&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F272 This study uses a rodent malaria model to seek correlation of tissue sequestration patterns with expression of members of the large gene family, cir. The re-annotation of the cir gene family is an important contribution (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5239182 Mon, 19 Sep 2011 04:00:00 +0100 5239182 http://www.medworm.com/index.php?rid=5227399&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F268 In vitro drug susceptibility patterns of a clinical isolate obtained from a patient who was infected in southeast Asia. The case report is of interest for the epidemiology of drug-resistant malaria and illustrates the possibility of artemisinin resistance with increased IC50 values (in contrast to the hypothesis of quiescence). (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5227399 Sun, 18 Sep 2011 04:00:00 +0100 5227399 http://www.medworm.com/index.php?rid=5227400&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F267 Results of histological comparisons between patients who died with cerebral and non cerebral malaria. An important contribution to understanding the pathophysiology of severe malaria. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5227400 Sat, 17 Sep 2011 04:00:00 +0100 5227400 http://www.medworm.com/index.php?rid=5227401&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F266 A panel of MSP4-specific Mabs was produced, recognizing six distinct epitopes that are also targeted by human antibodies during natural malaria infection. Antibodies directed to more than three epitope regions spread across MSP4 are likely to be required for P. falciparum growth inhibition in vitro. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5227401 Fri, 16 Sep 2011 04:00:00 +0100 5227401 http://www.medworm.com/index.php?rid=5227402&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F265 This study examines the factors associated with use of nets owned in Ghana. The results of this study suggest that net use would increase in Ghana if a number of features where taken into consideration. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5227402 Thu, 15 Sep 2011 04:00:00 +0100 5227402 http://www.medworm.com/index.php?rid=5227403&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F264 Cytokines have the ability to influence many aspects of an immune reaction. A disturbed balance in pro- and anti-inflammatory cytokine responses may affect parasitaemia and pathology in vivax malaria. The study provides interesting insights into the importance of IL10 and IFN-gamma gene polymorphisms during Plasmodium vivax infections. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5227403 Wed, 14 Sep 2011 04:00:00 +0100 5227403 http://www.medworm.com/index.php?rid=5227404&cid=s_34081_20_f&fid=34081&url=http%3A%2F%2Fwww.malariajournal.com%2Fcontent%2F10%2F1%2F263 This paper gives a detailed review of the pharmacokinetic properties of artesunate, and its active metabolite dihydroartemisinin, following all routes of administration. (Source: Malaria Journal) Malaria Journal journals http://www.medworm.com/rss/comments.php?id=5227404 Tue, 13 Sep 2011 04:00:00 +0100 5227404