MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Mayo Clinic Proceedings' source. Mon, 30 Jan 2012 12:52:10 +0100 http://www.medworm.com/index.php?rid=5463561&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F12%2F1248%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5463561 Thu, 01 Dec 2011 05:00:00 +0100 5463561 http://www.medworm.com/index.php?rid=5463560&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F12%2F1247%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5463560 Thu, 01 Dec 2011 05:00:00 +0100 5463560 http://www.medworm.com/index.php?rid=5463559&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F12%2F1245%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5463559 Thu, 01 Dec 2011 05:00:00 +0100 5463559 http://www.medworm.com/index.php?rid=5463558&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F12%2F1244%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5463558 Thu, 01 Dec 2011 05:00:00 +0100 5463558 http://www.medworm.com/index.php?rid=5463557&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F12%2F1243%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5463557 Thu, 01 Dec 2011 05:00:00 +0100 5463557 http://www.medworm.com/index.php?rid=5463556&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F12%2F1230%3Frss%3D1 Gram-positive bacteria cause a broad spectrum of disease in immunocompetent and immunocompromised hosts. Despite increasing knowledge about resistance transmission patterns and new antibiotics, these organisms continue to cause significant morbidity and mortality, especially in the health care setting. Methicillin-resistant Staphylococcus aureus poses major problems worldwide as a cause of nosocomial infection and has emerged as a cause of community-acquired infections. This change in epidemiology affects choices of empirical antibiotics for skin and skin-structure infections and community-acquired pneumonia in many settings. Throughout the world, the treatment of community-acquired pneumonia and other respiratory tract infections caused by penicillin-resistant Streptococcus pneumoniae has... Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5463556 Thu, 01 Dec 2011 05:00:00 +0100 5463556 http://www.medworm.com/index.php?rid=5463555&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F12%2F1225%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5463555 Thu, 01 Dec 2011 05:00:00 +0100 5463555 http://www.medworm.com/index.php?rid=5463554&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F12%2F1211%3Frss%3D1 Treatment of seniors with Parkinson disease is within the domain of primary care physicians and internists. A good working knowledge of carbidopa/levodopa principles should allow excellent care of most patients, at least during the early years of the disease. Even later, when levodopa responses become more complicated (eg, dyskinesias, motor fluctuations, insomnia, anxiety), levodopa adjustments may be all that is necessary. A dozen tips for optimizing treatment of Parkinson disease are discussed herein. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5463554 Thu, 01 Dec 2011 05:00:00 +0100 5463554 http://www.medworm.com/index.php?rid=5463553&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F12%2F1198%3Frss%3D1 Every year more than 500,000 patients present to the emergency department with cocaine-associated complications, most commonly chest pain. Many of these patients undergo extensive work-up and treatment. Much of the evidence regarding cocaine’s cardiovascular effects, as well as the current management of cocaine-associated chest pain and acute coronary syndromes, is anecdotally derived and based on studies written more than 2 decades ago that involved only a few patients. Newer studies have brought into question many of the commonly held theories and practices regarding the etiology, diagnosis, and treatment of this common clinical scenario. However, there continues to be a paucity of prospective, randomized trials addressing this topic as it relates to clinical outcomes. We searched ... Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5463553 Thu, 01 Dec 2011 05:00:00 +0100 5463553 http://www.medworm.com/index.php?rid=5463552&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F12%2F1192%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5463552 Thu, 01 Dec 2011 05:00:00 +0100 5463552 http://www.medworm.com/index.php?rid=5463551&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F12%2F1188%3Frss%3D1 Ruxolitinib (INCB018424) is a JAK1 and JAK2 inhibitor recently evaluated for the treatment of myelofibrosis (MF) in early- and advanced-phase clinical trials. In 2 recent communications that focused on short-term and long-term ruxolitinib treatment outcome, respectively, the drug was shown to be effective in controlling constitutional symptoms and splenomegaly but was also associated with important adverse effects, including moderate to severe thrombocytopenia and anemia. The most recent of the 2 communications focused on 51 Mayo Clinic patients who participated in the original phase 1/2 ruxolitinib clinical trial and highlighted a high treatment discontinuation rate (92% after a median time of 9.2 months), primarily for loss of treatment benefit but also because of drug-associated adverse... Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5463551 Thu, 01 Dec 2011 05:00:00 +0100 5463551 http://www.medworm.com/index.php?rid=5463550&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F12%2F1181%3Frss%3D1 We developed a computerized medical informatics tool to identify patients who had a culture performed on a sterile body site specimen during their hospitalization that subsequently turned positive after hospital dismissal. During a 13-month period, 533 patients had a positive culture identified by our Computer-Based Antimicrobial Monitoring (CBAM) program after hospital dismissal, and 112 (21%) of these culture results necessitated an intervention and communication with the primary health care professional. Thirty-two (29%) of positive cultures were from the blood. Thirty-eight (34%) of the CBAM interventions with available outcome data resulted in initiation of, change in, or prolongation of outpatient antimicrobial therapy. The CBAM program serves an important role in optimizing patient ... Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5463550 Thu, 01 Dec 2011 05:00:00 +0100 5463550 http://www.medworm.com/index.php?rid=5463549&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F12%2F1174%3Frss%3D1 CONCLUSION: Unsedated techniques may be acceptable, feasible, and safe alternatives to sEGD to screen for BE in the community. Trial Registration: clinicaltrials.gov identifier: NCT00943280 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5463549 Thu, 01 Dec 2011 05:00:00 +0100 5463549 http://www.medworm.com/index.php?rid=5463548&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F12%2F1165%3Frss%3D1 CONCLUSION: In patients with atherosclerotic renal artery stenosis, the change in eGFR after RAI was related to plaque composition classified by VH-IVUS. The evaluation of plaque composition may provide more insights into the change in renal function after RAI. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5463548 Thu, 01 Dec 2011 05:00:00 +0100 5463548 http://www.medworm.com/index.php?rid=5463547&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F12%2F1161%3Frss%3D1 CONCLUSION: Medication errors occur frequently in patients with CKD admitted with ACS and result in a high risk of in-hospital bleeding. Use of CPOE with decision support is feasible in the ACS setting and may lead to improved patient safety. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5463547 Thu, 01 Dec 2011 05:00:00 +0100 5463547 http://www.medworm.com/index.php?rid=5463546&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F12%2F1154%3Frss%3D1 CONCLUSION: Our results suggest that NT-proBNP is a more robust cardiac biomarker compared with ANP or NT-proANP and is independently predictive of mortality and HF in the general population free of overt HF. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5463546 Thu, 01 Dec 2011 05:00:00 +0100 5463546 http://www.medworm.com/index.php?rid=5463545&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F12%2F1146%3Frss%3D1 CONCLUSION: Novel algorithms incorporating multiple streams of electronic health data can reasonably detect herpes zoster and PHN. These algorithms could facilitate meaningful public health surveillance using electronic health data. The incidence of PHN may be increasing. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5463545 Thu, 01 Dec 2011 05:00:00 +0100 5463545 http://www.medworm.com/index.php?rid=5463544&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F12%2F1143%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5463544 Thu, 01 Dec 2011 05:00:00 +0100 5463544 http://www.medworm.com/index.php?rid=5463543&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F12%2F1141%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5463543 Thu, 01 Dec 2011 05:00:00 +0100 5463543 http://www.medworm.com/index.php?rid=5463542&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F12%2F1138%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5463542 Thu, 01 Dec 2011 05:00:00 +0100 5463542 http://www.medworm.com/index.php?rid=5463541&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F12%2Fe54%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5463541 Thu, 01 Dec 2011 05:00:00 +0100 5463541 http://www.medworm.com/index.php?rid=5463540&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F12%2Fe53%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5463540 Thu, 01 Dec 2011 05:00:00 +0100 5463540 http://www.medworm.com/index.php?rid=5371959&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F11%2F1126-a%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5371959 Thu, 27 Oct 2011 04:00:00 +0100 5371959 http://www.medworm.com/index.php?rid=5371958&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F11%2F1126%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5371958 Thu, 27 Oct 2011 04:00:00 +0100 5371958 http://www.medworm.com/index.php?rid=5371957&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F11%2F1125%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5371957 Thu, 27 Oct 2011 04:00:00 +0100 5371957 http://www.medworm.com/index.php?rid=5371956&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F11%2F1124%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5371956 Thu, 27 Oct 2011 04:00:00 +0100 5371956 http://www.medworm.com/index.php?rid=5371955&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F11%2F1113%3Frss%3D1 Antimicrobial resistance is increasing; however, antimicrobial drug development is slowing. Now more than ever before, antimicrobial stewardship is of the utmost importance as a way to optimize the use of antimicrobials to prevent the development of resistance and improve patient outcomes. This review describes the why, what, who, how, when, and where of antimicrobial stewardship. Techniques of stewardship are summarized, and a plan for implementation of a stewardship program is outlined. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5371955 Thu, 27 Oct 2011 04:00:00 +0100 5371955 http://www.medworm.com/index.php?rid=5371954&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F11%2F1109%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5371954 Thu, 27 Oct 2011 04:00:00 +0100 5371954 http://www.medworm.com/index.php?rid=5371953&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F11%2F1104%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5371953 Thu, 27 Oct 2011 04:00:00 +0100 5371953 http://www.medworm.com/index.php?rid=5371952&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F11%2F1095%3Frss%3D1 Endomyocardial biopsy (EMB) is widely used for surveillance of cardiac allograft rejection and for the diagnosis of unexplained ventricular dysfunction. Typically, EMB is performed through the jugular or femoral veins and is associated with a serious acute complication rate of less than 1% using current flexible bioptomes. Although it is accepted that EMB should be used to monitor for rejection after transplant, use of EMB for the diagnosis of various myocardial diseases is controversial. Diagnosis of myocardial disease in the nontransplant recipient is often successful via noninvasive investigations including laboratory evaluation; echocardiography, nuclear studies, and magnetic resonance imaging can yield specific diagnoses in the absence of invasive EMB. Therefore, use of the technique ... Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5371952 Thu, 27 Oct 2011 04:00:00 +0100 5371952 http://www.medworm.com/index.php?rid=5371951&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F11%2F1086%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5371951 Thu, 27 Oct 2011 04:00:00 +0100 5371951 http://www.medworm.com/index.php?rid=5371950&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F11%2F1075%3Frss%3D1 CONCLUSION: The TNFSF8 polymorphisms rs927374 and rs2295800 were associated with neutrophil count. This finding suggests that post-MI inflammatory response is genetically modulated. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5371950 Thu, 27 Oct 2011 04:00:00 +0100 5371950 http://www.medworm.com/index.php?rid=5371949&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F11%2F1068%3Frss%3D1 CONCLUSION: The rate of symptomatic emboli associated with IE was reduced in patients who received continuous daily statin therapy before onset of IE. Despite fewer embolic events observed in patients who received antiplatelet agents, a significant association was not found after adjusting for propensity factors. A continued evaluation of these drugs and their potential impact on subsequent embolism among IE patients is warranted. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5371949 Thu, 27 Oct 2011 04:00:00 +0100 5371949 http://www.medworm.com/index.php?rid=5371948&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F11%2F1063%3Frss%3D1 CONCLUSION: Clinical outcome in patients with CPM is not predicted by the volume of radiologic T2 signal abnormality on MRI or the severity of hyponatremia. Serial brain imaging is of value because a substantial proportion of patients have normal findings on initial MRI. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5371948 Thu, 27 Oct 2011 04:00:00 +0100 5371948 http://www.medworm.com/index.php?rid=5371947&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F11%2F1056%3Frss%3D1 CONCLUSION: Among patients with CVD, both preexisting depression and anxiety, occurring on average 17 years before the CVD event, independently predict hospitalizations. In addition, the 2 conditions may act synergistically on increasing health care utilization in patients with CVD. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5371947 Thu, 27 Oct 2011 04:00:00 +0100 5371947 http://www.medworm.com/index.php?rid=5371946&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F11%2F1050%3Frss%3D1 CONCLUSION: We found that low vitamin D levels are associated with depressive symptoms, especially in persons with a history of depression. These findings suggest that primary care patients with a history of depression may be an important target for assessment of vitamin D levels. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5371946 Thu, 27 Oct 2011 04:00:00 +0100 5371946 http://www.medworm.com/index.php?rid=5371945&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F11%2F1042%3Frss%3D1 CONCLUSION: Hyperglycemia (FPG, ≥110 mg/dL), even below the DM threshold (such as with impaired fasting glucose), was associated with a higher risk of fatal, nonfatal, or total stroke events in asymptomatic men. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5371945 Thu, 27 Oct 2011 04:00:00 +0100 5371945 http://www.medworm.com/index.php?rid=5371944&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F11%2F1038%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5371944 Thu, 27 Oct 2011 04:00:00 +0100 5371944 http://www.medworm.com/index.php?rid=5371943&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F11%2Fe52%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5371943 Thu, 27 Oct 2011 04:00:00 +0100 5371943 http://www.medworm.com/index.php?rid=5371942&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F11%2Fe51%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5371942 Thu, 27 Oct 2011 04:00:00 +0100 5371942 http://www.medworm.com/index.php?rid=5371941&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F11%2Fe50%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5371941 Thu, 27 Oct 2011 04:00:00 +0100 5371941 http://www.medworm.com/index.php?rid=5279938&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F10%2F1027-a%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5279938 Fri, 30 Sep 2011 04:00:00 +0100 5279938 http://www.medworm.com/index.php?rid=5279937&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F10%2F1027%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5279937 Fri, 30 Sep 2011 04:00:00 +0100 5279937 http://www.medworm.com/index.php?rid=5279936&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F10%2F1009%3Frss%3D1 This article provides an overview of clinically available antiviral drugs for the primary care physician, with a special focus on pharmacology, clinical uses, and adverse effects. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5279936 Fri, 30 Sep 2011 04:00:00 +0100 5279936 http://www.medworm.com/index.php?rid=5279935&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F10%2F1005%3Frss%3D1 We report a case of alcohol-induced rhabdomyolysis that responded dramatically to high-dose corticosteroids. A 55-year-old man presented to the emergency department for evaluation of diffuse muscle pain, weakness, and darkening urine. On admission, his creatine kinase (CK) level was 50,022 U/L. Despite aggressive fluid repletion, his CK level continued to increase, peaking at 401,280 U/L with a concomitant increase in muscle pain and urine darkening. On administration of high-dose corticosteroids, clinical symptoms and CK levels improved dramatically, and the patient was discharged 36 hours later with complete resolution of muscle pain and weakness. Given their low toxicity profile, short-term high-dose corticosteroids may be a valid treatment option for recurrent rhabdomyolysis unresponsi... Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5279935 Fri, 30 Sep 2011 04:00:00 +0100 5279935 http://www.medworm.com/index.php?rid=5279934&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F10%2F1002%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5279934 Fri, 30 Sep 2011 04:00:00 +0100 5279934 http://www.medworm.com/index.php?rid=5279933&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F10%2F999%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5279933 Fri, 30 Sep 2011 04:00:00 +0100 5279933 http://www.medworm.com/index.php?rid=5279932&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F10%2F981%3Frss%3D1 The worldwide incidence of malignant melanoma has been increasing during the past decade and is a public health concern because this disease accounts for up to 90% of deaths from cutaneous malignancies. It remains a devastating disease with few therapeutic options once in an advanced stage. Current methods of detection, prognostication, and monitoring of melanoma focus on clinical, morphologic, and histopathologic characteristics of measurable tumor. Although this information provides some insight into disease behavior and outcome, melanoma is still an unpredictable disease. Significant effort has been put into finding an informative serologic biomarker. However, the marker remains elusive, and investigations continue. Using the PubMed database, we reviewed the published literature on sero... Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5279932 Fri, 30 Sep 2011 04:00:00 +0100 5279932 http://www.medworm.com/index.php?rid=5279931&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F10%2F973%3Frss%3D1 Meaningful health reform in the United States must improve the health of the population while lowering costs. In an effort to provide a framework for doing so, the Institute of Health Care Improvement created the triple aim, which encompasses the goals of (1) improving individual health and experience with the health care system, (2) improving population health, and (3) decreasing the rate of per capita health care costs. Current reform efforts have focused on the development of Patient-Centered Medical Homes (an innovative team-based model of care that facilitates a partnership between the patient’s personal physician coordinating care throughout a patient’s lifetime to maximize health outcomes), but these relatively narrow efforts are focused on office practice and payment me... Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5279931 Fri, 30 Sep 2011 04:00:00 +0100 5279931 http://www.medworm.com/index.php?rid=5279930&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F10%2F960%3Frss%3D1 CONCLUSION: The REACH Registry, a large international study of individuals with atherothrombotic disease, documents the important ethnic-specific differences in cardiovascular risk factors and variations in cardiovascular mortality that currently exist worldwide. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5279930 Fri, 30 Sep 2011 04:00:00 +0100 5279930 http://www.medworm.com/index.php?rid=5279929&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F10%2F948%3Frss%3D1 CONCLUSION: This post hoc subanalysis shows that MAP0004 was effective in treating migraine irrespective of the time of treatment, even more than 8 hours after onset of migraine pain. Trial Registration: clinicaltrials.gov identifier: NCT00623636 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5279929 Fri, 30 Sep 2011 04:00:00 +0100 5279929 http://www.medworm.com/index.php?rid=5279928&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F10%2F941%3Frss%3D1 CONCLUSION: Nearly 30% of the victims of swimming-related drowning hosted a cardiac channel mutation. Genetic testing should be considered in the postmortem evaluation of an unexplained drowning, especially if a positive personal or family history is elicited. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5279928 Fri, 30 Sep 2011 04:00:00 +0100 5279928 http://www.medworm.com/index.php?rid=5279927&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F10%2F933%3Frss%3D1 CONCLUSION: Predictive genomic risk information modestly influences risk perception and worry. The extent and direction of this influence may depend on the condition being tested and its baseline prominence in preventive health care and may attenuate with time. Trial Registration: clinicaltrials.gov identifier: NCT00782366 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5279927 Fri, 30 Sep 2011 04:00:00 +0100 5279927 http://www.medworm.com/index.php?rid=5279926&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F10%2F930%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5279926 Fri, 30 Sep 2011 04:00:00 +0100 5279926 http://www.medworm.com/index.php?rid=5279925&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F10%2F929%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5279925 Fri, 30 Sep 2011 04:00:00 +0100 5279925 http://www.medworm.com/index.php?rid=5279924&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F10%2F922%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5279924 Fri, 30 Sep 2011 04:00:00 +0100 5279924 http://www.medworm.com/index.php?rid=5279923&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F10%2Fe49%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5279923 Fri, 30 Sep 2011 04:00:00 +0100 5279923 http://www.medworm.com/index.php?rid=5178624&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F9%2F917-a%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5178624 Mon, 29 Aug 2011 23:00:00 +0100 5178624 http://www.medworm.com/index.php?rid=5178623&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F9%2F917%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5178623 Mon, 29 Aug 2011 23:00:00 +0100 5178623 http://www.medworm.com/index.php?rid=5178622&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F9%2F916-a%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5178622 Mon, 29 Aug 2011 23:00:00 +0100 5178622 http://www.medworm.com/index.php?rid=5178621&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F9%2F916%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5178621 Mon, 29 Aug 2011 23:00:00 +0100 5178621 http://www.medworm.com/index.php?rid=5178620&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F9%2F912%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5178620 Mon, 29 Aug 2011 23:00:00 +0100 5178620 http://www.medworm.com/index.php?rid=5178619&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F9%2F907%3Frss%3D1 Fibromyalgia (FM) is a common chronic widespread pain disorder. Our understanding of FM has increased substantially in recent years with extensive research suggesting a neurogenic origin for the most prominent symptom of FM, chronic widespread pain. Neurochemical imbalances in the central nervous system are associated with central amplification of pain perception characterized by allodynia (a heightened sensitivity to stimuli that are not normally painful) and hyperalgesia (an increased response to painful stimuli). Despite this increased awareness and understanding, FM remains undiagnosed in an estimated 75% of people with the disorder. Clinicians could more effectively diagnose and manage FM if they better understood its underlying mechanisms. Fibromyalgia is a disorder of pain processin... Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5178619 Mon, 29 Aug 2011 23:00:00 +0100 5178619 http://www.medworm.com/index.php?rid=5178618&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F9%2F903%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5178618 Mon, 29 Aug 2011 23:00:00 +0100 5178618 http://www.medworm.com/index.php?rid=5178617&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F9%2F894%3Frss%3D1 Many adolescents and adults with asthma continue to have poorly controlled disease, often attributable to poor adherence to asthma therapy. Failure to adhere to recommended treatment may result from a desire to avoid regular reliance on medications, inappropriate high tolerance of asthma symptoms, failure to perceive the chronic nature of asthma, and poor inhaler technique. Primary care physicians need to find opportunities and methods to address these and other issues related to poor asthma control. Few adolescents or adults with asthma currently have asthma "checkup" visits, usually seeking medical care only with an exacerbation. Therefore, nonrespiratory-related office visits represent an important opportunity to assess baseline asthma control and the factors that most commonly lead to ... Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5178617 Mon, 29 Aug 2011 23:00:00 +0100 5178617 http://www.medworm.com/index.php?rid=5178616&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F9%2F885%3Frss%3D1 Elderly patients who have an acute illness or who undergo surgery often experience cognitive decline. The pathophysiologic mechanisms that cause neurodegeneration resulting in cognitive decline, including protein deposition and neuroinflammation, also play a role in animal models of surgery-induced cognitive decline. With the aging of the population, surgical candidates of advanced age with underlying neurodegeneration are encountered more often, raising concerns that, in patients with this combination, cognitive function will precipitously decline postoperatively. This special article is based on a symposium that the University of California, San Francisco, convened to explore the contributions of surgery and anesthesia to the development of cognitive decline in the aged patient. A road m... Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5178616 Mon, 29 Aug 2011 23:00:00 +0100 5178616 http://www.medworm.com/index.php?rid=5178615&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F9%2F876%3Frss%3D1 A rapidly growing literature strongly suggests that exercise, specifically aerobic exercise, may attenuate cognitive impairment and reduce dementia risk. We used PubMed (keywords exercise and cognition) and manuscript bibliographies to examine the published evidence of a cognitive neuroprotective effect of exercise. Meta-analyses of prospective studies documented a significantly reduced risk of dementia associated with midlife exercise; similarly, midlife exercise significantly reduced later risks of mild cognitive impairment in several studies. Among patients with dementia or mild cognitive impairment, randomized controlled trials (RCTs) documented better cognitive scores after 6 to 12 months of exercise compared with sedentary controls. Meta-analyses of RCTs of aerobic exercise in health... Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5178615 Mon, 29 Aug 2011 23:00:00 +0100 5178615 http://www.medworm.com/index.php?rid=5178614&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F9%2F869%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5178614 Mon, 29 Aug 2011 23:00:00 +0100 5178614 http://www.medworm.com/index.php?rid=5178613&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F9%2F865%3Frss%3D1 CONCLUSION: At least 80% of patients prefer full disclosure of the risk of POVL, by the surgeon, during a face-to-face discussion before the day of scheduled surgery. This finding supports development of a national patient-driven guideline for disclosing the risk of POVL before prone spinal surgery. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5178613 Mon, 29 Aug 2011 23:00:00 +0100 5178613 http://www.medworm.com/index.php?rid=5178612&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F9%2F857%3Frss%3D1 CONCLUSION: Although both low BF and low BMI are independent predictors of mortality in patients with CHD, only patients with combined low BF/low BMI appear to be at particularly high risk of mortality during follow-up. Studies are needed to determine optimal body composition in the secondary prevention of CHD. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5178612 Mon, 29 Aug 2011 23:00:00 +0100 5178612 http://www.medworm.com/index.php?rid=5178611&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F9%2F851%3Frss%3D1 CONCLUSION: Our results suggest that the clinical syndrome of eclampsia is associated with an anatomical substrate that is recognizable by neuroimaging as PRES. The levels of blood pressure elevation are lower than those reported in cases of PRES because of hypertensive encephalopathy. Further studies are needed to determine whether more aggressive blood pressure control and early neuroimaging may have a role in the management of these patients. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5178611 Mon, 29 Aug 2011 23:00:00 +0100 5178611 http://www.medworm.com/index.php?rid=5178610&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F9%2F845%3Frss%3D1 CONCLUSION: This study involving patients with spontaneous coronary artery dissection demonstrates the feasibility of and is a successful model for developing a "virtual" multicenter disease registry through disease-specific social media networks to better characterize an uncommon condition. This study is a prime example of patient-initiated research that could be used by other health care professionals and institutions. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5178610 Mon, 29 Aug 2011 23:00:00 +0100 5178610 http://www.medworm.com/index.php?rid=5178609&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F9%2F838%3Frss%3D1 CONCLUSION: Robot-assisted MV repair using proven, conventional open-repair techniques is reproducible and safe and hastens recovery for all categories of leaflet prolapse. One month after surgery, significant regression in left ventricular size and volume is evident. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5178609 Mon, 29 Aug 2011 23:00:00 +0100 5178609 http://www.medworm.com/index.php?rid=5178608&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F9%2F836%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5178608 Mon, 29 Aug 2011 23:00:00 +0100 5178608 http://www.medworm.com/index.php?rid=5178607&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F9%2F834%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5178607 Mon, 29 Aug 2011 23:00:00 +0100 5178607 http://www.medworm.com/index.php?rid=5178606&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F9%2Fe48%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5178606 Mon, 29 Aug 2011 23:00:00 +0100 5178606 http://www.medworm.com/index.php?rid=5178605&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F9%2Fe47%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5178605 Mon, 29 Aug 2011 23:00:00 +0100 5178605 http://www.medworm.com/index.php?rid=5075008&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F8%2F824-a%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5075008 Thu, 28 Jul 2011 23:00:00 +0100 5075008 http://www.medworm.com/index.php?rid=5075007&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F8%2F824%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5075007 Thu, 28 Jul 2011 23:00:00 +0100 5075007 http://www.medworm.com/index.php?rid=5075006&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F8%2F821%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5075006 Thu, 28 Jul 2011 23:00:00 +0100 5075006 http://www.medworm.com/index.php?rid=5075005&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F8%2F820%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5075005 Thu, 28 Jul 2011 23:00:00 +0100 5075005 http://www.medworm.com/index.php?rid=5075004&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F8%2F818%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5075004 Thu, 28 Jul 2011 23:00:00 +0100 5075004 http://www.medworm.com/index.php?rid=5075003&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F8%2F805%3Frss%3D1 This article reviews key pharmacological aspects of systemic antifungal agents as well as evolving strategies, such as pharmacokinetic-pharmacodynamic optimization and therapeutic drug monitoring, to improve the safety and efficacy of systemic antifungal therapy. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5075003 Thu, 28 Jul 2011 23:00:00 +0100 5075003 http://www.medworm.com/index.php?rid=5075002&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F8%2F801%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5075002 Thu, 28 Jul 2011 23:00:00 +0100 5075002 http://www.medworm.com/index.php?rid=5075001&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F8%2F792%3Frss%3D1 Suicide is a public health problem and a leading cause of death. The number of people thinking seriously about suicide, making plans, and attempting suicide is surprisingly high. In total, primary care clinicians write more prescriptions for antidepressants than mental health clinicians and see patients more often in the month before their death by suicide. Treatment of depression by primary care physicians is improving, but opportunities remain in addressing suicide-related treatment variables. Collaborative care models for treating depression have the potential both to improve depression outcomes and decrease suicide risk. Alcohol use disorders and anxiety symptoms are important comorbid conditions to identify and treat. Management of suicide risk includes understanding the difference be... Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5075001 Thu, 28 Jul 2011 23:00:00 +0100 5075001 http://www.medworm.com/index.php?rid=5075000&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F8%2F788%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5075000 Thu, 28 Jul 2011 23:00:00 +0100 5075000 http://www.medworm.com/index.php?rid=5074999&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F8%2F781%3Frss%3D1 In August 2010, the Third Annual Mayo Clinic Conference on Systems Engineering and Operations Research in Health Care was held. The continuing mission of the conference is to gather a multidisciplinary group of systems engineers, clinicians, administrators, and academic professors to discuss the translation of systems engineering methods to more effective health care delivery. Education, research, and practice were enhanced via a mix of formal presentations, tutorials, and informal gatherings of participants with diverse backgrounds. Although the conference promotes a diversity of perspectives and methods, participants are united in their desire to find ways in which systems engineering can transform health care, especially in the context of health care reform and other significant changes... Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5074999 Thu, 28 Jul 2011 23:00:00 +0100 5074999 http://www.medworm.com/index.php?rid=5074998&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F8%2F762%3Frss%3D1 Statins (3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors) represent the cornerstone of drug therapy to reduce low-density lipoprotein (LDL) cholesterol and cardiovascular risk. However, even optimal statin management of LDL cholesterol leaves many patients with residual cardiovascular risk, in part because statins are more effective in reducing LDL cholesterol than apolipoprotein B (Apo B). Apo B may be a better marker of atherogenic risk than LDL cholesterol because Apo B measures the total number of all atherogenic particles (total atherosclerotic burden), including LDL, very low-density lipoprotein, intermediate-density lipoprotein, remnant lipoproteins, and lipoprotein(a). To determine whether Apo B is a better indicator of baseline cardiovascular risk and residual risk afte... Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5074998 Thu, 28 Jul 2011 23:00:00 +0100 5074998 http://www.medworm.com/index.php?rid=5074997&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F8%2F748%3Frss%3D1 The perioperative management of patients with inflammatory bowel disease is challenging given the altered immune system that results from a variety of biologic and immunomodulator therapies. Clinicians are often faced with challenges and complicated equations when deciding on the type and dose of medication. To understand the effect of these medications and review the evidence regarding the management of these medications in the perioperative setting, a PubMed-based literature search (January 1, 1960, through April 1, 2011) was conducted using the following search terms: perioperative management, risk, outcome, inflammatory bowel disease, ulcerative colitis, Crohn's disease, aminosalicylates, glucocorticoids, purine analogues, cyclosporine, methotrexate, biologic therapy, infliximab, and t... Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5074997 Thu, 28 Jul 2011 23:00:00 +0100 5074997 http://www.medworm.com/index.php?rid=5074996&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F8%2F738%3Frss%3D1 CONCLUSION: In the presence of CLL or NHL, MFH seems to behave more aggressively, suggested by the increased likelihood of metastases compared with controls without prior CLL or NHL. However, overall survival does not appear to be worse in cases of MFH and CLL or NHL than in MFH alone. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5074996 Thu, 28 Jul 2011 23:00:00 +0100 5074996 http://www.medworm.com/index.php?rid=5074995&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F8%2F730%3Frss%3D1 CONCLUSION: The LAVI significantly predicts mortality risk, independent of LV geometry, and adds to the overall mortality prediction in a large cohort of patients with preserved systolic function. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5074995 Thu, 28 Jul 2011 23:00:00 +0100 5074995 http://www.medworm.com/index.php?rid=5074994&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F8%2F721%3Frss%3D1 CONCLUSION: In this series, a small-diameter uniportal approach has eliminated intercostal neuralgia. Selecting a T1-T2 sympathotomy yields an excellent palmar response, with a very low severe compensatory hyperhidrosis complication rate. The low failure rate was noted during 18 months of follow-up and suggests that longer follow-up is necessary in these patients. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5074994 Thu, 28 Jul 2011 23:00:00 +0100 5074994 http://www.medworm.com/index.php?rid=5074993&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F8%2F719%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5074993 Thu, 28 Jul 2011 23:00:00 +0100 5074993 http://www.medworm.com/index.php?rid=5074992&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F8%2F717%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5074992 Thu, 28 Jul 2011 23:00:00 +0100 5074992 http://www.medworm.com/index.php?rid=5074991&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F8%2F713%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5074991 Thu, 28 Jul 2011 23:00:00 +0100 5074991 http://www.medworm.com/index.php?rid=5074990&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F8%2Fe46%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5074990 Thu, 28 Jul 2011 23:00:00 +0100 5074990 http://www.medworm.com/index.php?rid=5074989&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F8%2Fe45%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=5074989 Thu, 28 Jul 2011 23:00:00 +0100 5074989 http://www.medworm.com/index.php?rid=4990283&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F7%2F709%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4990283 Wed, 29 Jun 2011 23:00:00 +0100 4990283 http://www.medworm.com/index.php?rid=4990282&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F7%2F708-a%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4990282 Wed, 29 Jun 2011 23:00:00 +0100 4990282 http://www.medworm.com/index.php?rid=4990281&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F7%2F708%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4990281 Wed, 29 Jun 2011 23:00:00 +0100 4990281 http://www.medworm.com/index.php?rid=4990280&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F7%2F707%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4990280 Wed, 29 Jun 2011 23:00:00 +0100 4990280 http://www.medworm.com/index.php?rid=4990279&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F7%2F706%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4990279 Wed, 29 Jun 2011 23:00:00 +0100 4990279 http://www.medworm.com/index.php?rid=4990278&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F7%2F705%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4990278 Wed, 29 Jun 2011 23:00:00 +0100 4990278 http://www.medworm.com/index.php?rid=4990277&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F7%2F703-a%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4990277 Wed, 29 Jun 2011 23:00:00 +0100 4990277 http://www.medworm.com/index.php?rid=4990276&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F7%2F703%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4990276 Wed, 29 Jun 2011 23:00:00 +0100 4990276 http://www.medworm.com/index.php?rid=4990275&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F7%2F702%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4990275 Wed, 29 Jun 2011 23:00:00 +0100 4990275 http://www.medworm.com/index.php?rid=4990274&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F7%2F686%3Frss%3D1 Antimicrobial prophylaxis is commonly used by clinicians for the prevention of numerous infectious diseases, including herpes simplex infection, rheumatic fever, recurrent cellulitis, meningococcal disease, recurrent uncomplicated urinary tract infections in women, spontaneous bacterial peritonitis in patients with cirrhosis, influenza, infective endocarditis, pertussis, and acute necrotizing pancreatitis, as well as infections associated with open fractures, recent prosthetic joint placement, and bite wounds. Perioperative antimicrobial prophylaxis is recommended for various surgical procedures to prevent surgical site infections. Optimal antimicrobial agents for prophylaxis should be bactericidal, nontoxic, inexpensive, and active against the typical pathogens that can cause surgical sit... Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4990274 Wed, 29 Jun 2011 23:00:00 +0100 4990274 http://www.medworm.com/index.php?rid=4990273&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F7%2F681%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4990273 Wed, 29 Jun 2011 23:00:00 +0100 4990273 http://www.medworm.com/index.php?rid=4990272&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F7%2F673%3Frss%3D1 This article defines compounded bioidentical HT and explores the similarities and differences between it and US Food and Drug Administration–approved HT. We will examine the major claims made by proponents of compounded bioidentical HT and recommend strategies for management of patients who request bioidentical HT from physicians. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4990272 Wed, 29 Jun 2011 23:00:00 +0100 4990272 http://www.medworm.com/index.php?rid=4990271&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F7%2F662%3Frss%3D1 Deep brain stimulation (DBS) has developed during the past 20 years as a remarkable treatment option for several different disorders. Advances in technology and surgical techniques have essentially replaced ablative procedures for most of these conditions. Stimulation of the ventralis intermedius nucleus of the thalamus has clearly been shown to markedly improve tremor control in patients with essential tremor and tremor related to Parkinson disease. Symptoms of bradykinesia, tremor, gait disturbance, and rigidity can be significantly improved in patients with Parkinson disease. Because of these improvements, a decrease in medication can be instrumental in reducing the disabling features of dyskinesias in such patients. Primary dystonia has been shown to respond well to DBS of the globus p... Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4990271 Wed, 29 Jun 2011 23:00:00 +0100 4990271 http://www.medworm.com/index.php?rid=4990270&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F7%2F649%3Frss%3D1 Renal artery stenosis (RAS) is characterized by a heterogeneous group of pathophysiologic entities, of which fibromuscular dysplasia and atherosclerotic RAS (ARAS) are the most common. Whether and which patients should undergo revascularization for ARAS is controversial. The general consensus is that all patients with ARAS should receive intensive medical treatment. The latest randomized clinical trials have increased confusion regarding recommendations for revascularization for ARAS. Although revascularization is not indicated in all patients with ARAS, experts agree that it should be considered in some patients, especially those with unstable angina, unexplained pulmonary edema, and hemodynamically significant ARAS with either worsening renal function or with difficult to control hyperte... Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4990270 Wed, 29 Jun 2011 23:00:00 +0100 4990270 http://www.medworm.com/index.php?rid=4990269&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F7%2F634%3Frss%3D1 This article briefly reviews current stem cell platforms, looking specifically at the two existing pluripotent lines available for potential therapeutic applications: hES cells and induced pluripotent stem (iPS) cells. We submit iPS technology as a viable and possibly superior alternative for future medical and research endeavors as it obviates many ethical and resource-related concerns posed by hES cells while prospectively matching their potential for scientific use. However, while the clinical realities of iPS cells appear promising, we must recognize the current limitations of this technology, avoid hype, and articulate ethically acceptable medical and scientific goals. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4990269 Wed, 29 Jun 2011 23:00:00 +0100 4990269 http://www.medworm.com/index.php?rid=4990268&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F7%2F626%3Frss%3D1 CONCLUSION: Potentially modifiable factors, such as patient-reported fast food intake, fish intake, and smoking, are independently associated with the omega-3 index in patients with AMI. These characteristics may be useful to identify patients who would benefit most from omega-3 supplementation and lifestyle modification. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4990268 Wed, 29 Jun 2011 23:00:00 +0100 4990268 http://www.medworm.com/index.php?rid=4990267&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F7%2F615%3Frss%3D1 CONCLUSION: Duloxetine was noninferior to pregabalin for the treatment of pain in patients with diabetic peripheral neuropathy who had an inadequate pain response to gabapentin. Trial Registration: clinicaltrials.gov Identifier: NCT00385671 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4990267 Wed, 29 Jun 2011 23:00:00 +0100 4990267 http://www.medworm.com/index.php?rid=4990266&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F7%2F606%3Frss%3D1 CONCLUSION: Genome-wide association studies have identified genetic variants associated with numerous phenotypes but have been historically limited by inadequate sample size due to costly genotyping and phenotyping. Large consortia with harmonized genotype data have been assembled to attain sufficient statistical power, but phenotyping remains a rate-limiting factor in gene discovery research efforts. The EMR consists of an abundance of phenotype data that can be extracted in a relatively quick and systematic manner. The MayoGC provides a model of a unique collaborative effort in the environment of a common EMR for the investigation of genetic determinants of diseases. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4990266 Wed, 29 Jun 2011 23:00:00 +0100 4990266 http://www.medworm.com/index.php?rid=4990265&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F7%2F603%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4990265 Wed, 29 Jun 2011 23:00:00 +0100 4990265 http://www.medworm.com/index.php?rid=4990264&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F7%2F600%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4990264 Wed, 29 Jun 2011 23:00:00 +0100 4990264 http://www.medworm.com/index.php?rid=4990263&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F7%2F597%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4990263 Wed, 29 Jun 2011 23:00:00 +0100 4990263 http://www.medworm.com/index.php?rid=4990262&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F7%2Fe44%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4990262 Wed, 29 Jun 2011 23:00:00 +0100 4990262 http://www.medworm.com/index.php?rid=4990261&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F7%2Fe40%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4990261 Wed, 29 Jun 2011 23:00:00 +0100 4990261 http://www.medworm.com/index.php?rid=4882180&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F6%2F588%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4882180 Mon, 30 May 2011 23:00:00 +0100 4882180 http://www.medworm.com/index.php?rid=4882179&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F6%2F586-a%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4882179 Mon, 30 May 2011 23:00:00 +0100 4882179 http://www.medworm.com/index.php?rid=4882178&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F6%2F586%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4882178 Mon, 30 May 2011 23:00:00 +0100 4882178 http://www.medworm.com/index.php?rid=4882177&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F6%2F584-a%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4882177 Mon, 30 May 2011 23:00:00 +0100 4882177 http://www.medworm.com/index.php?rid=4882176&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F6%2F584%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4882176 Mon, 30 May 2011 23:00:00 +0100 4882176 http://www.medworm.com/index.php?rid=4882175&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F6%2F561%3Frss%3D1 Parasitic diseases affect more than 2 billion people globally and cause substantial morbidity and mortality, particularly among the world's poorest people. This overview focuses on the treatment of the major protozoan and helminth infections in humans. Recent developments in antiparasitic therapy include the expansion of artemisinin-based therapies for malaria, new drugs for soil-transmitted helminths and intestinal protozoa, expansion of the indications for antiparasitic drug treatment in patients with Chagas disease, and the use of combination therapy for leishmaniasis and human African trypanosomiasis. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4882175 Mon, 30 May 2011 23:00:00 +0100 4882175 http://www.medworm.com/index.php?rid=4882174&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F6%2F557%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4882174 Mon, 30 May 2011 23:00:00 +0100 4882174 http://www.medworm.com/index.php?rid=4882173&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F6%2F556%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4882173 Mon, 30 May 2011 23:00:00 +0100 4882173 http://www.medworm.com/index.php?rid=4882172&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F6%2F549%3Frss%3D1 Obstructive sleep apnea (OSA) is a breathing disorder during sleep that has implications beyond disrupted sleep. It is increasingly recognized as an independent risk factor for cardiac, neurologic, and perioperative morbidities. Yet this disorder remains undiagnosed in a substantial portion of our population. It is imperative for all physicians to remain vigilant in identifying patients with signs and symptoms consistent with OSA. This review focuses on updates in the areas of terminology and testing, complications of untreated OSA, perioperative considerations, treatment options, and new developments in this field. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4882172 Mon, 30 May 2011 23:00:00 +0100 4882172 http://www.medworm.com/index.php?rid=4882171&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F6%2F544%3Frss%3D1 A 54-year-old man with no known cardiac disease collapsed outdoors in a small rural community. The cardiac arrest was witnessed, and immediate cardiopulmonary resuscitation was begun by a bystander and a trained first responder who was nearby. The patient was moved into a building across the street for continued resuscitation. First responders arrived with an automated external defibrillator, and ventricular fibrillation was documented. First responders delivered 6 defibrillation shocks, 4 of which transiently restored an organized electrocardiographic rhythm but with no pulse at any time. Additional emergency medical services personnel from nearby communities and an advanced life support (ALS) flight crew arrived. The flight crew initiated ALS care. The trachea was intubated, ventilation ... Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4882171 Mon, 30 May 2011 23:00:00 +0100 4882171 http://www.medworm.com/index.php?rid=4882170&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F6%2F531%3Frss%3D1 Heart failure with preserved ejection fraction (HF-PEF) is the clinical syndrome of heart failure associated with normal or near-normal systolic function. Because inhibition of the adrenergic and renin-angiotensin-aldosterone systems has been so effective in the treatment of systolic heart failure, these same therapies have been the subject of recent clinical trials of HF-PEF. In this review, we examine the current evidence about treatment of HF-PEF, with particular emphasis on reviewing the literature for large-scale randomized clinical studies. The lack of significant benefit with neurohormonal antagonism in HF-PEF suggests that this condition might not involve neurohormonal activation as a critical pathophysiologic mechanism. Perhaps heart failure as we traditionally think of it is the ... Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4882170 Mon, 30 May 2011 23:00:00 +0100 4882170 http://www.medworm.com/index.php?rid=4882169&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F6%2F522%3Frss%3D1 Currently, no data from randomized controlled clinical trials are available to guide the depth of resection for intermediate-thickness primary cutaneous melanoma. Thus, we hypothesized that substantial variability exists in this aspect of surgical care. We have summarized the literature regarding depth of resection and report the results of our survey of surgeons who treat melanoma. Most of the 320 respondents resected down to, but did not include, the muscular fascia (extremity, 71%; trunk, 66%; and head and neck, 62%). However, significant variation exists. We identified variability in our own practice and have elected to standardize this common aspect of routine surgical care across our institution. In light of the lack of evidence to support resection of the deep muscular fascia, we ha... Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4882169 Mon, 30 May 2011 23:00:00 +0100 4882169 http://www.medworm.com/index.php?rid=4882168&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F6%2F509%3Frss%3D1 CONCLUSION: The associations between CHADS2 covariates and increased bleeding risk were weak, with the exception of age. Given the known association of the CHADS2 score and stroke risk, the decision to prescribe warfarin should be driven more by patients' risk of stroke than by the risk of bleeding. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4882168 Mon, 30 May 2011 23:00:00 +0100 4882168 http://www.medworm.com/index.php?rid=4882167&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F6%2F493%3Frss%3D1 CONCLUSION: Proactive palliative medicine consultation for patients being considered for or being treated with DT improves advance care planning and thus contributes to better overall care of these patients. Our experience highlights focused advance care planning, thorough exploration of goals of care, and expert symptom management and end-of-life care when appropriate. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4882167 Mon, 30 May 2011 23:00:00 +0100 4882167 http://www.medworm.com/index.php?rid=4882166&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F6%2F489%3Frss%3D1 CONCLUSION: Patients with Cowden syndrome have a heavy colon polyp burden with a wide pathologic spectrum, both benign and malignant. The colon polyposis results in a previously unreported morbidity with a high colectomy rate. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4882166 Mon, 30 May 2011 23:00:00 +0100 4882166 http://www.medworm.com/index.php?rid=4882165&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F6%2F480%3Frss%3D1 CONCLUSION: From a payer perspective, nitrofurantoin appears to be a reasonable alternative to TMP-SMX and fluoroquinolones for empirical treatment of uncomplicated UTIs, especially given the current prevalence of antibiotic resistance among community uropathogens. On the basis of efficacy, cost, and low impact on promoting antimicrobial resistance, clinicians should consider nitrofurantoin as a reasonable alternative to TMP-SMX and fluoroquinolones for first-line therapy for uncomplicated UTIs. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4882165 Mon, 30 May 2011 23:00:00 +0100 4882165 http://www.medworm.com/index.php?rid=4882164&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F6%2F477%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4882164 Mon, 30 May 2011 23:00:00 +0100 4882164 http://www.medworm.com/index.php?rid=4882163&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F6%2Fe39%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4882163 Mon, 30 May 2011 23:00:00 +0100 4882163 http://www.medworm.com/index.php?rid=4882162&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F6%2Fe35%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4882162 Mon, 30 May 2011 23:00:00 +0100 4882162 http://www.medworm.com/index.php?rid=4766877&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F5%2F469-c%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4766877 Thu, 28 Apr 2011 23:00:00 +0100 4766877 http://www.medworm.com/index.php?rid=4766875&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F5%2F469-a%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4766875 Thu, 28 Apr 2011 23:00:00 +0100 4766875 http://www.medworm.com/index.php?rid=4766874&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F5%2F469%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4766874 Thu, 28 Apr 2011 23:00:00 +0100 4766874 http://www.medworm.com/index.php?rid=4766873&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F5%2F465%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4766873 Thu, 28 Apr 2011 23:00:00 +0100 4766873 http://www.medworm.com/index.php?rid=4766872&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F5%2F457%3Frss%3D1 Fibromyalgia (FM) is a chronic widespread pain disorder often seen in primary care practices. Advances in the understanding of FM pathophysiology and clinical presentation have improved the recognition and diagnosis of FM in clinical practice. Fibromyalgia is a clinical diagnosis based on signs and symptoms and is appropriate for primary care practitioners to make. The hallmark symptoms used to identify FM are chronic widespread pain, fatigue, and sleep disturbances. Awareness of common mimics of FM and comorbid disorders will increase confidence in establishing a diagnosis of FM. (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4766872 Thu, 28 Apr 2011 23:00:00 +0100 4766872 http://www.medworm.com/index.php?rid=4766871&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F5%2F444%3Frss%3D1 Nephropathy is a common microvascular complication among patients with type 2 diabetes mellitus and a major cause of kidney failure. It is characterized by albuminuria (≥300 mg/d) and a reduced glomerular filtration rate and is often present at the time of diabetes diagnosis after the kidney has been exposed to chronic hyperglycemia during the prediabetic phase. A low glomerular filtration rate (<60 mL/min/1.73 m2) is also an independent risk factor for cardiovascular events and death. Detection of diabetic nephropathy during its initial stages provides the opportunity for early therapeutic interventions to prevent or delay the onset of complications and improve outcomes. An intensive and multifactorial management approach is needed that targets all risk determinants simultaneously. ... Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4766871 Thu, 28 Apr 2011 23:00:00 +0100 4766871 http://www.medworm.com/index.php?rid=4766870&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F5%2F427%3Frss%3D1 Rhinosinusitis (RS) affects approximately 1 in 7 adults in the United States, and its effect on quality of life, productivity, and finances is substantial. During the past 10 years, several expert panels from authoritative bodies have published evidence-based guidelines for the diagnosis and management of RS and its subtypes, including acute viral RS, acute bacterial RS, chronic RS (CRS) without nasal polyposis, CRS with nasal polyposis, and allergic fungal RS. This review examines and compares the recommendations of the Rhinosinusitis Initiative, the Joint Task Force on Practice Parameters, the Clinical Practice Guideline: Adult Sinusitis, the European Position Paper on Rhinosinusitis and Nasal Polyps 2007, and the British Society for Allergy and Clinical Immunology. Points of consensus a... Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4766870 Thu, 28 Apr 2011 23:00:00 +0100 4766870 http://www.medworm.com/index.php?rid=4766869&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F5%2F421%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4766869 Thu, 28 Apr 2011 23:00:00 +0100 4766869 http://www.medworm.com/index.php?rid=4766868&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F5%2F419%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4766868 Thu, 28 Apr 2011 23:00:00 +0100 4766868 http://www.medworm.com/index.php?rid=4766867&cid=s_36819_49_f&fid=36819&url=http%3A%2F%2Fmayoclinicproceedings.com%2Fcgi%2Fcontent%2Fshort%2F86%2F5%2F414%3Frss%3D1 (Source: Mayo Clinic Proceedings) Mayo Clinic Proceedings journals http://www.medworm.com/rss/comments.php?id=4766867 Thu, 28 Apr 2011 23:00:00 +0100 4766867