MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Nature Biotechnology' source. Thu, 09 Feb 2012 18:15:15 +0100 http://www.medworm.com/index.php?rid=5674079&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FuVif1dQGnP8%2Fnbt.2124 Nature Biotechnology 30, 196 (2012). doi:10.1038/nbt.2124 (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674079 Wed, 08 Feb 2012 05:00:00 +0100 5674079 http://www.medworm.com/index.php?rid=5674078&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FI8yPdxzt2rw%2Fnbt.2123 Nature Biotechnology 30, 195 (2012). doi:10.1038/nbt.2123 Author: Michael Francisco (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674078 Wed, 08 Feb 2012 05:00:00 +0100 5674078 http://www.medworm.com/index.php?rid=5674077&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FzvadUHENlNE%2Fnbt0212-193f Authors: Swathi Padmanabhan, Tahir Amin, Bhaven Sampat, Robert Cook-Deegan & Subhashini Chandrasekharan (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674077 Wed, 08 Feb 2012 05:00:00 +0100 5674077 http://www.medworm.com/index.php?rid=5674076&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FSfkxMZD1K0Y%2Fnbt0212-193e Authors: Hepeng Jia & Karen Carey (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674076 Wed, 08 Feb 2012 05:00:00 +0100 5674076 http://www.medworm.com/index.php?rid=5674075&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2F4R_PesGDpkU%2Fnbt0212-193d Nature Biotechnology 30, 193 (2012). doi:10.1038/nbt0212-193d Author: Mark Ratner (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674075 Wed, 08 Feb 2012 05:00:00 +0100 5674075 http://www.medworm.com/index.php?rid=5674074&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FkTjj0FGHTvQ%2Fnbt0212-193c Nature Biotechnology 30, 193 (2012). doi:10.1038/nbt0212-193c Author: Cormac Sheridan (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674074 Wed, 08 Feb 2012 05:00:00 +0100 5674074 http://www.medworm.com/index.php?rid=5674073&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2Fw6h5mG7NW8I%2Fnbt0212-193b Authors: Guo-Yun Chen, Xi Chen, Samantha King, Karen A Cavassani, Jiansong Cheng, Xincheng Zheng, Hongzhi Cao, Hai Yu, Jingyao Qu, Dexing Fang, Wei Wu, Xue-Feng Bai, Jin-Qing Liu, Shireen A Woodiga, Chong Chen, Lei Sun, Cory M Hogaboam, Steven L Kunkel, Pan Zheng & Yang Liu (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674073 Wed, 08 Feb 2012 05:00:00 +0100 5674073 http://www.medworm.com/index.php?rid=5674072&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FXVUt4niNHs4%2Fnbt0212-193a Authors: Obidimma C Ezezika, Abdallah S Daar, Kathryn Barber, Justin Mabeya, Fiona Thomas, Jennifer Deadman, Debbie Wang & Peter A Singer (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674072 Wed, 08 Feb 2012 05:00:00 +0100 5674072 http://www.medworm.com/index.php?rid=5674065&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2Fh9Y0SGeM364%2Fnbt.2131 Nature Biotechnology 30, 158 (2012). doi:10.1038/nbt.2131 Author: Jason Kreisberg (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674065 Wed, 08 Feb 2012 05:00:00 +0100 5674065 http://www.medworm.com/index.php?rid=5674064&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2Fn3HFezDywg8%2Fnbt.2130 Nature Biotechnology 30, 158 (2012). doi:10.1038/nbt.2130 Author: Markus Elsner (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674064 Wed, 08 Feb 2012 05:00:00 +0100 5674064 http://www.medworm.com/index.php?rid=5674063&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FsDBcbyM6j1c%2Fnbt.2129 Nature Biotechnology 30, 158 (2012). doi:10.1038/nbt.2129 Author: Susan Jones (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674063 Wed, 08 Feb 2012 05:00:00 +0100 5674063 http://www.medworm.com/index.php?rid=5674062&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FAPAVilK_62c%2Fnbt.2128 Nature Biotechnology 30, 158 (2012). doi:10.1038/nbt.2128 Author: Susan Jones (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674062 Wed, 08 Feb 2012 05:00:00 +0100 5674062 http://www.medworm.com/index.php?rid=5674061&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FYHaJxL-FMDs%2Fnbt.2127 TAL effector–DNA structure Nature Biotechnology 30, 158 (2012). doi:10.1038/nbt.2127 Author: Laura DeFrancesco (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674061 Wed, 08 Feb 2012 05:00:00 +0100 5674061 http://www.medworm.com/index.php?rid=5674060&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FfwETH_eAd6I%2Fnbt.2114 Nature Biotechnology 30, 156 (2012). doi:10.1038/nbt.2114 Author: Margaret A Liu Optimized AAV vectors encoding broadly neutralizing antibodies against HIV show promise in mice. (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674060 Wed, 08 Feb 2012 05:00:00 +0100 5674060 http://www.medworm.com/index.php?rid=5674059&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FhMt0RUfJSmk%2Fnbt.2118 Authors: Jamie K Scott, Ralph Pantophlet & Lisa Craig A new computational strategy facilitates de novo design of discontinuous epitopes on protein scaffolds. (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674059 Wed, 08 Feb 2012 05:00:00 +0100 5674059 http://www.medworm.com/index.php?rid=5674058&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FRqF3v3ifPCY%2Fnbt.2117 Authors: Mark W Majesky & Christine L Mummery A method for differentiating human pluripotent stem cells into several subtypes of smooth muscle cell should aid the study and treatment of vascular disease. (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674058 Wed, 08 Feb 2012 05:00:00 +0100 5674058 http://www.medworm.com/index.php?rid=5674057&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2F6wJGXoRF2EE%2Fnbt.2125 Nature Biotechnology 30, 151 (2012). doi:10.1038/nbt.2125 (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674057 Wed, 08 Feb 2012 05:00:00 +0100 5674057 http://www.medworm.com/index.php?rid=5674056&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FKsKrqCV0loY%2Fnbt.2110 Nature Biotechnology 30, 148 (2012). doi:10.1038/nbt.2110 Author: Deepak Hegde (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674056 Wed, 08 Feb 2012 05:00:00 +0100 5674056 http://www.medworm.com/index.php?rid=5674055&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FZEF_mInhW6o%2Fnbt.2116 Personal medicine—the new banking crisis Nature Biotechnology 30, 141 (2012). doi:10.1038/nbt.2116 Authors: Christopher Thomas Scott, Timothy Caulfield, Emily Borgelt & Judy Illes (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674055 Wed, 08 Feb 2012 05:00:00 +0100 5674055 http://www.medworm.com/index.php?rid=5674054&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FWY__EhC-mNg%2Fnbt.2094 Nature Biotechnology 30, 139 (2012). doi:10.1038/nbt.2094 Author: Brady Huggett (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674054 Wed, 08 Feb 2012 05:00:00 +0100 5674054 http://www.medworm.com/index.php?rid=5674053&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FfQKnyuSkK_w%2Fnbt.2113 OpenVigil—free eyeballs on AERS pharmacovigilance data Nature Biotechnology 30, 137 (2012). doi:10.1038/nbt.2113 Authors: Ruwen Böhm, Jan Höcker, Ingolf Cascorbi & Thomas Herdegen (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674053 Wed, 08 Feb 2012 05:00:00 +0100 5674053 http://www.medworm.com/index.php?rid=5674052&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FS004FlBl_jY%2Fnbt.2112 Authors: Rui Wang, Antonio Fabregat, Daniel Ríos, David Ovelleiro, Joseph M Foster, Richard G Côté, Johannes Griss, Attila Csordas, Yasset Perez-Riverol, Florian Reisinger, Henning Hermjakob, Lennart Martens & Juan Antonio Vizcaíno (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674052 Wed, 08 Feb 2012 05:00:00 +0100 5674052 http://www.medworm.com/index.php?rid=5674051&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2Fhj51jdg1vzc%2Fnbt.2093 Nature Biotechnology 30, 132 (2012). doi:10.1038/nbt.2093 Author: Kenneth E Eheman (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674051 Wed, 08 Feb 2012 05:00:00 +0100 5674051 http://www.medworm.com/index.php?rid=5674050&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FZLFx8GjyEeo%2Fnbt.2111 Nature Biotechnology 30, 128 (2012). doi:10.1038/nbt.2111 Author: Jim Kling (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674050 Wed, 08 Feb 2012 05:00:00 +0100 5674050 http://www.medworm.com/index.php?rid=5674049&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FxyPSV-uycD0%2Fnbt.2119 2011—Big biotechs gorge on debt Nature Biotechnology 30, 127 (2012). doi:10.1038/nbt.2119 Author: Walter Yang (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674049 Wed, 08 Feb 2012 05:00:00 +0100 5674049 http://www.medworm.com/index.php?rid=5674048&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FPS6nP0nJX9o%2Fnbt0212-126b Nature Biotechnology 30, 126 (2012). doi:10.1038/nbt0212-126b (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674048 Wed, 08 Feb 2012 05:00:00 +0100 5674048 http://www.medworm.com/index.php?rid=5674047&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FJKg2RoaOEJM%2Fnbt0212-126a Life Technologies promises $1,000 genome Nature Biotechnology 30, 126 (2012). doi:10.1038/nbt0212-126a Author: Laura DeFrancesco (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674047 Wed, 08 Feb 2012 05:00:00 +0100 5674047 http://www.medworm.com/index.php?rid=5674046&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FXDLJ-do1t0Q%2Fnbt0212-125 Nature Biotechnology 30, 125 (2012). doi:10.1038/nbt0212-125 Author: Nuala Moran (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674046 Wed, 08 Feb 2012 05:00:00 +0100 5674046 http://www.medworm.com/index.php?rid=5674045&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FKsL6N7vu9fQ%2Fnbt0212-124c Nature Biotechnology 30, 124 (2012). doi:10.1038/nbt0212-124c Author: Susan Aldridge (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674045 Wed, 08 Feb 2012 05:00:00 +0100 5674045 http://www.medworm.com/index.php?rid=5674044&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FWVfdgURdbyE%2Fnbt0212-124b Nature Biotechnology 30, 124 (2012). doi:10.1038/nbt0212-124b Author: Killugudi Jayaraman (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674044 Wed, 08 Feb 2012 05:00:00 +0100 5674044 http://www.medworm.com/index.php?rid=5674043&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FkMnuxjkTWGo%2Fnbt0212-124a Nature Biotechnology 30, 124 (2012). doi:10.1038/nbt0212-124a Author: Gunjan Sinha (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674043 Wed, 08 Feb 2012 05:00:00 +0100 5674043 http://www.medworm.com/index.php?rid=5674042&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FQCbGljrC6Fc%2Fnbt0212-123 Nature Biotechnology 30, 123 (2012). doi:10.1038/nbt0212-123 Author: Charlotte Harrison (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674042 Wed, 08 Feb 2012 05:00:00 +0100 5674042 http://www.medworm.com/index.php?rid=5674041&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2F1qvPs0L2UhI%2Fnbt0212-122b Nature Biotechnology 30, 122 (2012). doi:10.1038/nbt0212-122b Author: Jennifer Rohn (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674041 Wed, 08 Feb 2012 05:00:00 +0100 5674041 http://www.medworm.com/index.php?rid=5674040&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FjYj0wuAe1_A%2Fnbt0212-122a Gilead's $11 billion HCV bet Nature Biotechnology 30, 122 (2012). doi:10.1038/nbt0212-122a Author: Karen Carey (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674040 Wed, 08 Feb 2012 05:00:00 +0100 5674040 http://www.medworm.com/index.php?rid=5674039&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FhHx-1ntqHPQ%2Fnbt0212-121a Nature Biotechnology 30, 121 (2012). doi:10.1038/nbt0212-121a Author: Michael Eisenstein (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674039 Wed, 08 Feb 2012 05:00:00 +0100 5674039 http://www.medworm.com/index.php?rid=5674038&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FNCAT0GQq1b8%2Fnbt0212-121b Nature Biotechnology 30, 121 (2012). doi:10.1038/nbt0212-121b Author: Ken Garber (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674038 Wed, 08 Feb 2012 05:00:00 +0100 5674038 http://www.medworm.com/index.php?rid=5674037&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FXoVVJlCVYk8%2Fnbt0212-119 Nature Biotechnology 30, 119 (2012). doi:10.1038/nbt0212-119 Author: Mark Ratner (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674037 Wed, 08 Feb 2012 05:00:00 +0100 5674037 http://www.medworm.com/index.php?rid=5674036&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FegVKIh8yXkM%2Fnbt.2133 Nature Biotechnology 30, 117 (2012). doi:10.1038/nbt.2133 (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674036 Wed, 08 Feb 2012 05:00:00 +0100 5674036 http://www.medworm.com/index.php?rid=5674035&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FZ50gyvzrxCI%2Fnbt.2132 Nature Biotechnology 30, vii (2012). doi:10.1038/nbt.2132 (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674035 Wed, 08 Feb 2012 05:00:00 +0100 5674035 http://www.medworm.com/index.php?rid=5674071&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FCB18GqzBmnU%2Fnbt.2109 Authors: Christopher B Eiben, Justin B Siegel, Jacob B Bale, Seth Cooper, Firas Khatib, Betty W Shen, Foldit Players, Barry L Stoddard, Zoran Popovic & David Baker Computational enzyme design holds promise for the production of renewable fuels, drugs and chemicals. De novo enzyme design has generated catalysts for several reactions, but with lower catalytic efficiencies than naturally occurring enzymes. Here we report the use of game-driven crowdsourcing to enhance the activity of a computationally designed enzyme through the functional remodeling of its structure. Players of the online game Foldit were challenged to remodel the backbone of a computationally designed bimolecular Diels-Alderase to enable additional interactions with substrates. Several iterations of design and character... Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674071 Sun, 22 Jan 2012 05:00:00 +0100 5674071 http://www.medworm.com/index.php?rid=5674070&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FwS3drYTVuuk%2Fnbt.2108 Authors: Ben-Quan Shen, Keyang Xu, Luna Liu, Helga Raab, Sunil Bhakta, Margaret Kenrick, Kathryn L Parsons-Reponte, Janet Tien, Shang-Fan Yu, Elaine Mai, Dongwei Li, Jay Tibbitts, Jakub Baudys, Ola M Saad, Suzie J Scales, Paul J McDonald, Philip E Hass, Charles Eigenbrot, Trung Nguyen, Willy A Solis, Reina N Fuji, Kelly M Flagella, Darshana Patel, Susan D Spencer, Leslie A Khawli, Allen Ebens, Wai Lee Wong, Richard Vandlen, Surinder Kaur, Mark X Sliwkowski, Richard H Scheller, Paul Polakis & Jagath R Junutula The reactive thiol in cysteine is used for coupling maleimide linkers in the generation of antibody conjugates. To assess the impact of the conjugation site, we engineered cysteines into a therapeutic HER2/neu antibody at three sites differing in solvent accessibility and local ch... Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674070 Sun, 22 Jan 2012 05:00:00 +0100 5674070 http://www.medworm.com/index.php?rid=5674068&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FkmkxTE6d7Tk%2Fnbt.2095 Authors: Akira Abe, Shunichi Kosugi, Kentaro Yoshida, Satoshi Natsume, Hiroki Takagi, Hiroyuki Kanzaki, Hideo Matsumura, Kakoto Yoshida, Chikako Mitsuoka, Muluneh Tamiru, Hideki Innan, Liliana Cano, Sophien Kamoun & Ryohei Terauchi (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674068 Sun, 22 Jan 2012 05:00:00 +0100 5674068 http://www.medworm.com/index.php?rid=5674069&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FpxK3O9GW8Aw%2Fnbt.2089 Authors: Suraj J Patel, Jack M Milwid, Kevin R King, Stefan Bohr, Arvin Iracheta-Velle, Matthew Li, Antonia Vitalo, Biju Parekkadan, Rohit Jindal & Martin L Yarmush Drug-induced liver injury (DILI) limits the development and application of many therapeutic compounds and presents major challenges to the pharmaceutical industry and clinical medicine. Acetaminophen-containing compounds are among the most frequently prescribed drugs and are also the most common cause of DILI. Here we describe a pharmacological strategy that targets gap junction communication to prevent amplification of fulminant hepatic failure and acetaminophen-induced hepatotoxicity. We demonstrate that connexin 32 (Cx32), a key hepatic gap junction protein, is an essential mediator of DILI by showing that mice deficient... Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674069 Sun, 15 Jan 2012 05:00:00 +0100 5674069 http://www.medworm.com/index.php?rid=5674067&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FaazbxiO_Cos%2Fnbt.2107 Generation of human vascular smooth muscle subtypes provides insight into embryological origin–dependent disease susceptibility Nature Biotechnology 30, 165 (2012). doi:10.1038/nbt.2107 Authors: Christine Cheung, Andreia S Bernardo, Matthew W B Trotter, Roger A Pedersen & Sanjay Sinha (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674067 Sun, 15 Jan 2012 05:00:00 +0100 5674067 http://www.medworm.com/index.php?rid=5674066&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FnXE92a79sZI%2Fnbt.2106 Authors: Xiujuan Wang, Xiaomu Wei, Bram Thijssen, Jishnu Das, Steven M Lipkin & Haiyuan Yu (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5674066 Sun, 15 Jan 2012 05:00:00 +0100 5674066 http://www.medworm.com/index.php?rid=5576874&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FTX0Zkfem8Pc%2Fnbt.2097 Nature Biotechnology 30, 116 (2012). doi:10.1038/nbt.2097 (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576874 Mon, 09 Jan 2012 05:00:00 +0100 5576874 http://www.medworm.com/index.php?rid=5576873&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2F6tx89WBE1vA%2Fnbt.2091 Nature Biotechnology 30, 113 (2012). doi:10.1038/nbt.2091 Author: Nathan L Vanderford To provide formal education and training required for PhDs to perform their complex, multidisciplinary job functions, traditional PhD curricula should be restructured to include mandatory professional development course work. (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576873 Mon, 09 Jan 2012 05:00:00 +0100 5576873 http://www.medworm.com/index.php?rid=5576872&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FVzIsND6OfYQ%2Fnbt0112-112f Nature Biotechnology 30, 112 (2012). doi:10.1038/nbt0112-112f Author: Cormac Sheridan (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576872 Mon, 09 Jan 2012 05:00:00 +0100 5576872 http://www.medworm.com/index.php?rid=5576871&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FLFXYYutYKPE%2Fnbt0112-112e Nature Biotechnology 30, 112 (2012). doi:10.1038/nbt0112-112e Author: Nuala Moran (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576871 Mon, 09 Jan 2012 05:00:00 +0100 5576871 http://www.medworm.com/index.php?rid=5576870&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2Foly1AXLEVVI%2Fnbt0112-112d Nature Biotechnology 30, 112 (2012). doi:10.1038/nbt0112-112d Author: Jim Kling (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576870 Mon, 09 Jan 2012 05:00:00 +0100 5576870 http://www.medworm.com/index.php?rid=5576869&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FdT_3XuBEtQA%2Fnbt0112-112c Nature Biotechnology 30, 112 (2012). doi:10.1038/nbt0112-112c Author: Laura DeFrancesco (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576869 Mon, 09 Jan 2012 05:00:00 +0100 5576869 http://www.medworm.com/index.php?rid=5576868&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FuLixrrk5_cE%2Fnbt0112-112b Authors: Kitai Kim, Rui Zhao, Akiko Doi, Kitwa Ng, Juli Unternaehrer, Patrick Cahan, Huo Hongguang, Yuin-Han Loh, Martin J Aryee, M William Lensch, Hu Li, James J Collins, Andrew P Feinberg & George Q Daley (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576868 Mon, 09 Jan 2012 05:00:00 +0100 5576868 http://www.medworm.com/index.php?rid=5576867&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FpDeZ7TviHq8%2Fnbt0112-112a Authors: Bruce L Booth & Bijan Salehizadeh (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576867 Mon, 09 Jan 2012 05:00:00 +0100 5576867 http://www.medworm.com/index.php?rid=5576861&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FAwFjgtu693g%2Fnbt.2076 The discovery and development of belimumab: the anti-BLyS–lupus connection Nature Biotechnology 30, 69 (2012). doi:10.1038/nbt.2076 Authors: William Stohl & David M Hilbert (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576861 Mon, 09 Jan 2012 05:00:00 +0100 5576861 http://www.medworm.com/index.php?rid=5576859&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FYrmfg2HmoLg%2Fnbt.2103 Nature Biotechnology 30, 60 (2012). doi:10.1038/nbt.2103 Author: Kathy Aschheim (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576859 Mon, 09 Jan 2012 05:00:00 +0100 5576859 http://www.medworm.com/index.php?rid=5576858&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2Fb_0f9JohRUQ%2Fnbt.2102 Nature Biotechnology 30, 60 (2012). doi:10.1038/nbt.2102 Author: Laura DeFrancesco (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576858 Mon, 09 Jan 2012 05:00:00 +0100 5576858 http://www.medworm.com/index.php?rid=5576857&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FaxbhxpEVWYY%2Fnbt.2101 Nature Biotechnology 30, 60 (2012). doi:10.1038/nbt.2101 Author: Markus Elsner (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576857 Mon, 09 Jan 2012 05:00:00 +0100 5576857 http://www.medworm.com/index.php?rid=5576856&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FYHEGPSbpgig%2Fnbt.2100 Nature Biotechnology 30, 60 (2012). doi:10.1038/nbt.2100 Author: Markus Elsner (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576856 Mon, 09 Jan 2012 05:00:00 +0100 5576856 http://www.medworm.com/index.php?rid=5576855&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FX-QCa6EBsCw%2Fnbt.2099 Nature Biotechnology 30, 60 (2012). doi:10.1038/nbt.2099 Author: Kathy Aschheim (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576855 Mon, 09 Jan 2012 05:00:00 +0100 5576855 http://www.medworm.com/index.php?rid=5576854&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FnyT8WmsJ8z4%2Fnbt.2092 Authors: Anastasia Khvorova & Alexey Wolfson An additional layer of RNA regulation in which RNAs encoded by genes and pseudogenes compete for microRNAs could offer new opportunities for oligonucleotide therapeutics. (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576854 Mon, 09 Jan 2012 05:00:00 +0100 5576854 http://www.medworm.com/index.php?rid=5576853&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2Fz4nsbNQmKGw%2Fnbt.2077 Nature Biotechnology 30, 56 (2012). doi:10.1038/nbt.2077 Author: Olle Lindvall A differentiation protocol guided by developmental principles produces more-authentic dopaminergic neurons for transplantation in patients. (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576853 Mon, 09 Jan 2012 05:00:00 +0100 5576853 http://www.medworm.com/index.php?rid=5576852&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FkYw6zQwlZdA%2Fnbt.2085 Nature Biotechnology 30, 55 (2012). doi:10.1038/nbt.2085 Author: Tom Misteli A new computational approach gives us the best chance at understanding how genomes are arranged in three-dimensional space and what that may mean for their function. (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576852 Mon, 09 Jan 2012 05:00:00 +0100 5576852 http://www.medworm.com/index.php?rid=5576851&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2F12a3FVia5fU%2Fnbt.2098 Nature Biotechnology 30, 54 (2012). doi:10.1038/nbt.2098 (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576851 Mon, 09 Jan 2012 05:00:00 +0100 5576851 http://www.medworm.com/index.php?rid=5576850&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FNF8KvbuyOds%2Fnbt.2082 Authors: Ganesan Marimuthu, Sangita Kumari, Muthukrishnakumar Kandasamy, Srivatsan Raghunathan & Gayatri Saberwal A look at the maintenance rates of US patents protecting FDA-approved biologics and small molecules. (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576850 Mon, 09 Jan 2012 05:00:00 +0100 5576850 http://www.medworm.com/index.php?rid=5576849&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FV-Wo8Qg9IKc%2Fnbt.2083 Nature Biotechnology 30, 41 (2012). doi:10.1038/nbt.2083 Author: Malorye Allison As R&D costs spiral for drug developers, disruptive approaches to clinical trial design and management are gaining traction. Get ready for electronic data capture, precompetitive data sharing, virtual trials and a variety of bold new paradigms. (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576849 Mon, 09 Jan 2012 05:00:00 +0100 5576849 http://www.medworm.com/index.php?rid=5576848&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FCG4lIgocEYw%2Fnbt.2088 Authors: Obidimma C Ezezika, Abdallah S Daar, Kathryn Barber, Justin Mabeya, Fiona Thomas, Jennifer Deadman, Debbie Wang & Peter A Singer (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576848 Mon, 09 Jan 2012 05:00:00 +0100 5576848 http://www.medworm.com/index.php?rid=5576847&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2Fj_xd0HsoOVI%2Fnbt.2078 Authors: Matthias Fladung, Illimar Altosaar, Detlef Bartsch, Marie Baucher, Fabio Boscaleri, Fernando Gallardo, Hely Häggman, Hans Hoenicka, Kaare Nielsen, Donatella Paffetti, Armand Séguin, Guenther Stotzky & Cristina Vettori (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576847 Mon, 09 Jan 2012 05:00:00 +0100 5576847 http://www.medworm.com/index.php?rid=5576846&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FWQuU30Xolmg%2Fnbt.2080 Authors: Yanhua Fan, Dov Borovsky, Chloe Hawkings, Almudena Ortiz-Urquiza & Nemat O Keyhani (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576846 Mon, 09 Jan 2012 05:00:00 +0100 5576846 http://www.medworm.com/index.php?rid=5576845&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2Fc2y07KRybkg%2Fnbt.2079 Authors: Daniel MacLean & Sophien Kamoun (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576845 Mon, 09 Jan 2012 05:00:00 +0100 5576845 http://www.medworm.com/index.php?rid=5576844&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FJd_WGysdcOo%2Fnbt.2081 Authors: Bill Gruber & Emily Walsh (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576844 Mon, 09 Jan 2012 05:00:00 +0100 5576844 http://www.medworm.com/index.php?rid=5576843&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2F3ifAatf6EnQ%2Fnbt.2084 Nature Biotechnology 30, 26 (2012). doi:10.1038/nbt.2084 Author: Michael Eisenstein In spite of its modest performance in clinical trials, Benlysta may offer effective relief against lupus. But physicians are still working to identify the right patients. Michael Eisenstein reports. (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576843 Mon, 09 Jan 2012 05:00:00 +0100 5576843 http://www.medworm.com/index.php?rid=5576842&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FxdQP7FwbLoU%2Fnbt.2086 Authors: Natalie D DeWitt, Michael P Yaffe & Alan Trounson By devoting funding to whole-genome studies, such as epigenetic and copy-number variation in stem cells, research on new genomic technology, and standards for methodologies and data collection/sharing, CIRM can spur both basic and translational research. (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576842 Mon, 09 Jan 2012 05:00:00 +0100 5576842 http://www.medworm.com/index.php?rid=5576841&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FBoKTsWSRdK8%2Fnbt.2087 Authors: John C Reed, E Lucile White, Jeffrey Aubé, Craig Lindsley, Min Li, Larry Sklar & Stuart Schreiber The NIH's proposed initiatives in translational science deserve solid financial backing from legislators and vocal support from the biomedical community. (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576841 Mon, 09 Jan 2012 05:00:00 +0100 5576841 http://www.medworm.com/index.php?rid=5576840&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FWuzh4GrXD-g%2Fnbt.2090 Nature Biotechnology 30, 15 (2012). doi:10.1038/nbt.2090 Author: H Craig Mak (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576840 Mon, 09 Jan 2012 05:00:00 +0100 5576840 http://www.medworm.com/index.php?rid=5576839&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2F8DpHyX7Y8r8%2Fnbt0112-14 Nature Biotechnology 30, 14 (2012). doi:10.1038/nbt0112-14 Author: Michael Eisenstein The Cambridge, Massachusetts–based company plans to introduce next-generation gene sequencing into oncology practice and pathologists' laboratories. (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576839 Mon, 09 Jan 2012 05:00:00 +0100 5576839 http://www.medworm.com/index.php?rid=5576838&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FYwHBQyX-Ukw%2Fnbt0112-13 Nature Biotechnology 30, 13 (2012). doi:10.1038/nbt0112-13 (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576838 Mon, 09 Jan 2012 05:00:00 +0100 5576838 http://www.medworm.com/index.php?rid=5576837&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FIVBGyihJons%2Fnbt0112-12 Nature Biotechnology 30, 12 (2012). doi:10.1038/nbt0112-12 Author: Simon Frantz (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576837 Mon, 09 Jan 2012 05:00:00 +0100 5576837 http://www.medworm.com/index.php?rid=5576836&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FVi9z3nLk0_A%2Fnbt0112-11 Nature Biotechnology 30, 11 (2012). doi:10.1038/nbt0112-11 Author: Lucas Laursen (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576836 Mon, 09 Jan 2012 05:00:00 +0100 5576836 http://www.medworm.com/index.php?rid=5576835&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FSsdMxfkiYx0%2Fnbt0112-9a Nature Biotechnology 30, 9 (2012). doi:10.1038/nbt0112-9a Author: Alla Katsnelson (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576835 Mon, 09 Jan 2012 05:00:00 +0100 5576835 http://www.medworm.com/index.php?rid=5576834&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FJ117RzuCoxk%2Fnbt0112-9b Nature Biotechnology 30, 9 (2012). doi:10.1038/nbt0112-9b Author: Jeffrey L Fox (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576834 Mon, 09 Jan 2012 05:00:00 +0100 5576834 http://www.medworm.com/index.php?rid=5576833&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FP3VKgyK8_EY%2Fnbt0112-8b $352 million into microRNA Nature Biotechnology 30, 8 (2012). doi:10.1038/nbt0112-8b Author: Sabine Louët (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576833 Mon, 09 Jan 2012 05:00:00 +0100 5576833 http://www.medworm.com/index.php?rid=5576832&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FaxPrQcNmBBk%2Fnbt0112-8a Nature Biotechnology 30, 8 (2012). doi:10.1038/nbt0112-8a Author: Emily Waltz (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576832 Mon, 09 Jan 2012 05:00:00 +0100 5576832 http://www.medworm.com/index.php?rid=5576831&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2Fi9_n_90rXjI%2Fnbt0112-6c Nature Biotechnology 30, 6 (2012). doi:10.1038/nbt0112-6c Author: Cormac Sheridan (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576831 Mon, 09 Jan 2012 05:00:00 +0100 5576831 http://www.medworm.com/index.php?rid=5576830&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FKFpZC4dHbIw%2Fnbt0112-6b Nature Biotechnology 30, 6 (2012). doi:10.1038/nbt0112-6b Author: Mark Ratner (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576830 Mon, 09 Jan 2012 05:00:00 +0100 5576830 http://www.medworm.com/index.php?rid=5576829&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2F61gNc39AVnU%2Fnbt0112-6a Nature Biotechnology 30, 6 (2012). doi:10.1038/nbt0112-6a Author: Karen Carey (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576829 Mon, 09 Jan 2012 05:00:00 +0100 5576829 http://www.medworm.com/index.php?rid=5576828&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FWhBJz8kW8UY%2Fnbt0112-4 Nature Biotechnology 30, 4 (2012). doi:10.1038/nbt0112-4 Author: Mark Ratner (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576828 Mon, 09 Jan 2012 05:00:00 +0100 5576828 http://www.medworm.com/index.php?rid=5576827&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FV5Ru-lADT5s%2Fnbt0112-3 Nature Biotechnology 30, 3 (2012). doi:10.1038/nbt0112-3 Author: Nuala Moran (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576827 Mon, 09 Jan 2012 05:00:00 +0100 5576827 http://www.medworm.com/index.php?rid=5576826&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2Feq-gr6MnGA4%2Fnbt.2096 Nature Biotechnology 30, 1 (2012). doi:10.1038/nbt.2096 Personalized medicine falls a long way short of the predictive and preventative healthcare paradigm it once promised. (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576826 Mon, 09 Jan 2012 05:00:00 +0100 5576826 http://www.medworm.com/index.php?rid=5576825&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FAuGsFeYf7_M%2Fnbt.2104 Nature Biotechnology 30, vii (2012). doi:10.1038/nbt.2104 (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576825 Mon, 09 Jan 2012 05:00:00 +0100 5576825 http://www.medworm.com/index.php?rid=5576864&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FG0kUGD1muus%2Fnbt.2057 Authors: Reza Kalhor, Harianto Tjong, Nimanthi Jayathilaka, Frank Alber & Lin Chen (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576864 Sun, 25 Dec 2011 05:00:00 +0100 5576864 http://www.medworm.com/index.php?rid=5576862&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2Fh45yPFmT_vA%2Fnbt.2065 Authors: Hugo Y K Lam, Michael J Clark, Rui Chen, Rong Chen, Georges Natsoulis, Maeve O'Huallachain, Frederick E Dewey, Lukas Habegger, Euan A Ashley, Mark B Gerstein, Atul J Butte, Hanlee P Ji & Michael Snyder (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576862 Sun, 18 Dec 2011 05:00:00 +0100 5576862 http://www.medworm.com/index.php?rid=5576860&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FXKg8u64DH6A%2Fnbt.2053 Authors: Joke Reumers, Peter De Rijk, Hui Zhao, Anthony Liekens, Dominiek Smeets, John Cleary, Peter Van Loo, Maarten Van Den Bossche, Kirsten Catthoor, Bernard Sabbe, Evelyn Despierre, Ignace Vergote, Brian Hilbush, Diether Lambrechts & Jurgen Del-Favero (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576860 Sun, 18 Dec 2011 05:00:00 +0100 5576860 http://www.medworm.com/index.php?rid=5576866&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FrAuibBhBjkc%2Fnbt.2050 Authors: Xun Xu, Xin Liu, Song Ge, Jeffrey D Jensen, Fengyi Hu, Xin Li, Yang Dong, Ryan N Gutenkunst, Lin Fang, Lei Huang, Jingxiang Li, Weiming He, Guojie Zhang, Xiaoming Zheng, Fumin Zhang, Yingrui Li, Chang Yu, Karsten Kristiansen, Xiuqing Zhang, Jian Wang, Mark Wright, Susan McCouch, Rasmus Nielsen, Jun Wang & Wen Wang (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576866 Sun, 11 Dec 2011 05:00:00 +0100 5576866 http://www.medworm.com/index.php?rid=5492726&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FlFFNSB4ERao%2Fnbt.2067 Nature Biotechnology 29, 1150 (2011). doi:10.1038/nbt.2067 (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492726 Thu, 08 Dec 2011 05:00:00 +0100 5492726 http://www.medworm.com/index.php?rid=5492725&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FH4D_oNaE058%2Fnbt.2062 Authors: Philipp von Roth, Benedict J Canny, Hans-Dieter Volk, J Alison Noble, Charles G Prober, Carsten Perka & Georg N Duda The increasing complexity of medical science poses significant challenges to medical education, leading to a growing gap between medical researchers and treating practitioners. (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492725 Thu, 08 Dec 2011 05:00:00 +0100 5492725 http://www.medworm.com/index.php?rid=5492717&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FiKpAYqlg4P0%2Fnbt.2073 Nature Biotechnology 29, 1101 (2011). doi:10.1038/nbt.2073 Author: Markus Elsner (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492717 Thu, 08 Dec 2011 05:00:00 +0100 5492717 http://www.medworm.com/index.php?rid=5492716&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2Fk0pojOkKbIM%2Fnbt.2072 Nature Biotechnology 29, 1101 (2011). doi:10.1038/nbt.2072 Author: Craig Mak (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492716 Thu, 08 Dec 2011 05:00:00 +0100 5492716 http://www.medworm.com/index.php?rid=5492715&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FUmR9gl77PGA%2Fnbt.2071 Nature Biotechnology 29, 1101 (2011). doi:10.1038/nbt.2071 Author: Markus Elsner (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492715 Thu, 08 Dec 2011 05:00:00 +0100 5492715 http://www.medworm.com/index.php?rid=5492714&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2Fv5ZWrZmw6m8%2Fnbt.2070 Nature Biotechnology 29, 1101 (2011). doi:10.1038/nbt.2070 Author: Craig Mak (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492714 Thu, 08 Dec 2011 05:00:00 +0100 5492714 http://www.medworm.com/index.php?rid=5492713&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FeG09lviAJis%2Fnbt.2069 Nature Biotechnology 29, 1101 (2011). doi:10.1038/nbt.2069 Author: Laura DeFrancesco (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492713 Thu, 08 Dec 2011 05:00:00 +0100 5492713 http://www.medworm.com/index.php?rid=5492712&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2F-di7UmMwsyM%2Fnbt.2061 Authors: Guoqiang Xu & Samie R Jaffrey Proteome-wide identification of ubiquitination events reveals their functional classes and identifies substrates for ubiquitin ligases. (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492712 Thu, 08 Dec 2011 05:00:00 +0100 5492712 http://www.medworm.com/index.php?rid=5492711&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FTBtd1XUY_TQ%2Fnbt.2064 Authors: PJ Hastings & Susan M Rosenberg Two studies illuminate why genome rearrangements in cancer cells occur where they do. (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492711 Thu, 08 Dec 2011 05:00:00 +0100 5492711 http://www.medworm.com/index.php?rid=5492710&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FzKmrdpsagMQ%2Fnbt.2063 Authors: David Dornan & Jeff Settleman Transcriptional profiling of single cells in colon tumors may enable prediction of patient outcomes. (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492710 Thu, 08 Dec 2011 05:00:00 +0100 5492710 http://www.medworm.com/index.php?rid=5492709&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FvFjpBmRjjAo%2Fnbt.2066 Nature Biotechnology 29, 1094 (2011). doi:10.1038/nbt.2066 (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492709 Thu, 08 Dec 2011 05:00:00 +0100 5492709 http://www.medworm.com/index.php?rid=5492708&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FtlU8ni8uwcc%2Fnbt.2056 Authors: David Kothamasi, Matthew Spurlock & E Toby Kiers Agricultural microbes have become an attractive target for patenting, but the lack of a consistent global patent regime and increasingly heated debates over microbial ownership rights are barriers to the development of this resource. (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492708 Thu, 08 Dec 2011 05:00:00 +0100 5492708 http://www.medworm.com/index.php?rid=5492707&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2Fj8XN-VaTlEw%2Fnbt.2060 What's fueling the biotech engine—2010 to 2011 Nature Biotechnology 29, 1083 (2011). doi:10.1038/nbt.2060 Author: Saurabh Aggarwal In the past year, biologics sector sales grew by single digits, driven by monoclonal antibodies and insulin products. New product launches are showing mixed results and are facing rising challenges from changes to reimbursement policies. (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492707 Thu, 08 Dec 2011 05:00:00 +0100 5492707 http://www.medworm.com/index.php?rid=5492706&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FXc1JoAziS6M%2Fnbt.2059 Nature Biotechnology 29, 1081 (2011). doi:10.1038/nbt.2059 Author: Mark Kessel (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492706 Thu, 08 Dec 2011 05:00:00 +0100 5492706 http://www.medworm.com/index.php?rid=5492705&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FYV70j8GdMlY%2Fnbt.2029 Nature Biotechnology 29, 1079 (2011). doi:10.1038/nbt.2029 Author: Aaron D Levine (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492705 Thu, 08 Dec 2011 05:00:00 +0100 5492705 http://www.medworm.com/index.php?rid=5492704&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FDBNMlZAiUHk%2Fnbt.2058 Nature Biotechnology 29, 1078 (2011). doi:10.1038/nbt.2058 Author: Alexei Tulin (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492704 Thu, 08 Dec 2011 05:00:00 +0100 5492704 http://www.medworm.com/index.php?rid=5492703&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FkXDv2PVp_CQ%2Fnbt.2055 Authors: Deepak Dugar & Gregory Stephanopoulos (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492703 Thu, 08 Dec 2011 05:00:00 +0100 5492703 http://www.medworm.com/index.php?rid=5492702&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2Fi0651Th7_yk%2Fnbt.2054 Authors: Moran Farhi, Elena Marhevka, Julius Ben-Ari, Anna Algamas-Dimantov, Zhuobin Liang, Vardit Zeevi, Orit Edelbaum, Ben Spitzer-Rimon, Hagai Abeliovich, Betty Schwartz, Tzvi Tzfira & Alexander Vainstein (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492702 Thu, 08 Dec 2011 05:00:00 +0100 5492702 http://www.medworm.com/index.php?rid=5492701&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2F1f1McQfGuKI%2Fbioe.2011.10 Nature Biotechnology 29, 1069 (2011). doi:10.1038/bioe.2011.10 Author: Bob Baltera Faced with limited funding and the need to find the most time- and cost-efficient route to proof of concept and relevance, how should you reorganize your company to facilitate development of your most valuable assets? (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492701 Thu, 08 Dec 2011 05:00:00 +0100 5492701 http://www.medworm.com/index.php?rid=5492700&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FCsBo8xaT2kg%2Fnbt1211-1068 Nature Biotechnology 29, 1068 (2011). doi:10.1038/nbt1211-1068 Author: Jennifer Rohn Zafgen hopes that small-molecule targeting of methionine aminopeptidase 2 (MetAP2), an enzyme originally associated with tumor angiogenesis, will lead to a new anti-obesity drug. (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492700 Thu, 08 Dec 2011 05:00:00 +0100 5492700 http://www.medworm.com/index.php?rid=5492699&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FSnhj7aN0bKA%2Fnbt1211-1066c Nature Biotechnology 29, 1066 (2011). doi:10.1038/nbt1211-1066c Author: Brady Huggett (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492699 Thu, 08 Dec 2011 05:00:00 +0100 5492699 http://www.medworm.com/index.php?rid=5492698&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FvNUpevSiBh8%2Fnbt1211-1066b Nature Biotechnology 29, 1066 (2011). doi:10.1038/nbt1211-1066b Author: Jeffrey L. Fox (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492698 Thu, 08 Dec 2011 05:00:00 +0100 5492698 http://www.medworm.com/index.php?rid=5492697&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FZ-QsTejVDHw%2Fnbt1211-1066a Jackson's $1.1 billion makeover Nature Biotechnology 29, 1066 (2011). doi:10.1038/nbt1211-1066a Author: Jennifer Rohn (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492697 Thu, 08 Dec 2011 05:00:00 +0100 5492697 http://www.medworm.com/index.php?rid=5492696&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FPC700r7mlEY%2Fnbt1211-1065 Nature Biotechnology 29, 1065 (2011). doi:10.1038/nbt1211-1065 (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492696 Thu, 08 Dec 2011 05:00:00 +0100 5492696 http://www.medworm.com/index.php?rid=5492695&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2Ff5wNWaNY-8o%2Fnbt1211-1063a Nature Biotechnology 29, 1063 (2011). doi:10.1038/nbt1211-1063a Author: Cormac Sheridan (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492695 Thu, 08 Dec 2011 05:00:00 +0100 5492695 http://www.medworm.com/index.php?rid=5492694&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FWEzKnr1YToo%2Fnbt1211-1063b Nature Biotechnology 29, 1063 (2011). doi:10.1038/nbt1211-1063b Author: Emily Walt (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492694 Thu, 08 Dec 2011 05:00:00 +0100 5492694 http://www.medworm.com/index.php?rid=5492693&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FrtKjQ-XXqls%2Fnbt1211-1062 Nature Biotechnology 29, 1062 (2011). doi:10.1038/nbt1211-1062 Author: Jeffrey L Fox (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492693 Thu, 08 Dec 2011 05:00:00 +0100 5492693 http://www.medworm.com/index.php?rid=5492692&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2F66ezZ6pggFg%2Fnbt1211-1060b Nature Biotechnology 29, 1060 (2011). doi:10.1038/nbt1211-1060b Author: Simon Franz (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492692 Thu, 08 Dec 2011 05:00:00 +0100 5492692 http://www.medworm.com/index.php?rid=5492691&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FEqy2zuszWM8%2Fnbt1211-1060a Nature Biotechnology 29, 1060 (2011). doi:10.1038/nbt1211-1060a Author: Brian Orelli (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492691 Thu, 08 Dec 2011 05:00:00 +0100 5492691 http://www.medworm.com/index.php?rid=5492690&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FwjmN6EsI03Y%2Fnbt1211-1058 Nature Biotechnology 29, 1058 (2011). doi:10.1038/nbt1211-1058 Author: Gunjan Sinha (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492690 Thu, 08 Dec 2011 05:00:00 +0100 5492690 http://www.medworm.com/index.php?rid=5492689&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2F7vFGfVbn-Hg%2Fnbt1211-1057 Nature Biotechnology 29, 1057 (2011). doi:10.1038/nbt1211-1057 Author: Nuala Moran (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492689 Thu, 08 Dec 2011 05:00:00 +0100 5492689 http://www.medworm.com/index.php?rid=5492688&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FSv0GuKnIElE%2Fnbt.2075 Nature Biotechnology 29, 1055 (2011). doi:10.1038/nbt.2075 A European high court ruling on the patentability of inventions related to human embryonic stem cells could promote secrecy and reduce access to data and cell lines. (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492688 Thu, 08 Dec 2011 05:00:00 +0100 5492688 http://www.medworm.com/index.php?rid=5492687&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FHrZrtCAJzPY%2Fnbt.2068 Nature Biotechnology 29, vii (2011). doi:10.1038/nbt.2068 (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492687 Thu, 08 Dec 2011 05:00:00 +0100 5492687 http://www.medworm.com/index.php?rid=5492724&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FILRkrJl8DD0%2Fnbt.2051 Authors: Katherine Amps, Peter W Andrews, George Anyfantis, Lyle Armstrong, Stuart Avery, Hossein Baharvand, Julie Baker, Duncan Baker, Maria B Munoz, Stephen Beil, Nissim Benvenisty, Dalit Ben-Yosef, Juan-Carlos Biancotti, Alexis Bosman, Romulo Martin Brena, Daniel Brison, Gunilla Caisander, María V Camarasa, Jieming Chen, Eric Chiao, Young Min Choi, Andre B H Choo, Daniel Collins, Alan Colman, Jeremy M Crook, George Q Daley, Anne Dalton, Paul A De Sousa, Chris Denning, Janet Downie, Petr Dvorak, Karen D Montgomery, Anis Feki, Angela Ford, Victoria Fox, Ana M Fraga, Tzvia Frumkin, Lin Ge, Paul J Gokhale, Tamar Golan-Lev, Hamid Gourabi, Michal Gropp, Lu Guangxiu, Ales Hampl, Katie Harron, Lyn Healy, Wishva Herath, Frida Holm, Outi Hovatta, Johan Hyllner, Maneesha S Inamdar, Astrid Kre... Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492724 Sun, 27 Nov 2011 05:00:00 +0100 5492724 http://www.medworm.com/index.php?rid=5492721&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FLnmySnVwrMQ%2Fnbt.2052 Authors: Kitai Kim, Rui Zhao, Akiko Doi, Kitwa Ng, Juli Unternaehrer, Patrick Cahan, Huo Hongguang, Yuin-Han Loh, Martin J Aryee, M William Lensch, Hu Li, James J Collins, Andrew P Feinberg & George Q Daley (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492721 Sun, 27 Nov 2011 05:00:00 +0100 5492721 http://www.medworm.com/index.php?rid=5492719&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FPuzaS1rzKY8%2Fnbt.2049 Authors: Geoff Fudenberg, Gad Getz, Matthew Meyerson & Leonid A Mirny (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492719 Sun, 20 Nov 2011 05:00:00 +0100 5492719 http://www.medworm.com/index.php?rid=5492718&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2Fx-LflQaZh-U%2Fnbt.2030 Authors: Subhajyoti De & Franziska Michor (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492718 Sun, 20 Nov 2011 05:00:00 +0100 5492718 http://www.medworm.com/index.php?rid=5576865&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FOY1k3LTEahE%2Fnbt.2024 Authors: Tim R Mercer, Daniel J Gerhardt, Marcel E Dinger, Joanna Crawford, Cole Trapnell, Jeffrey A Jeddeloh, John S Mattick & John L Rinn Transcriptomic analyses have revealed an unexpected complexity to the human transcriptome, whose breadth and depth exceeds current RNA sequencing capability. Using tiling arrays to target and sequence select portions of the transcriptome, we identify and characterize unannotated transcripts whose rare or transient expression is below the detection limits of conventional sequencing approaches. We use the unprecedented depth of coverage afforded by this technique to reach the deepest limits of the human transcriptome, exposing widespread, regulated and remarkably complex noncoding transcription in intergenic regions, as well as unannotated exons and ... Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5576865 Sun, 13 Nov 2011 05:00:00 +0100 5576865 http://www.medworm.com/index.php?rid=5492722&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2Flc8m2XN95vE%2Fnbt.2038 Authors: Piero Dalerba, Tomer Kalisky, Debashis Sahoo, Pradeep S Rajendran, Michael E Rothenberg, Anne A Leyrat, Sopheak Sim, Jennifer Okamoto, Darius M Johnston, Dalong Qian, Maider Zabala, Janet Bueno, Norma F Neff, Jianbin Wang, Andrew A Shelton, Brendan Visser, Shigeo Hisamori, Yohei Shimono, Marc van de Wetering, Hans Clevers, Michael F Clarke & Stephen R Quake (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5492722 Sun, 13 Nov 2011 05:00:00 +0100 5492722 http://www.medworm.com/index.php?rid=5396984&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2F8ddZUre6nZQ%2Fnbt.2045 Nature Biotechnology 29, 1054 (2011). doi:10.1038/nbt.2045 (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5396984 Tue, 08 Nov 2011 05:00:00 +0100 5396984 http://www.medworm.com/index.php?rid=5396983&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FBkNxkqCXV64%2Fnbt.2037 Nature Biotechnology 29, 1052 (2011). doi:10.1038/nbt.2037 Author: Michael Francisco (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5396983 Tue, 08 Nov 2011 05:00:00 +0100 5396983 http://www.medworm.com/index.php?rid=5396974&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FVfvVXtyN-rg%2Fnbt.2020 Authors: Ann D Kwong, Robert S Kauffman, Patricia Hurter & Peter Mueller (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5396974 Tue, 08 Nov 2011 05:00:00 +0100 5396974 http://www.medworm.com/index.php?rid=5396973&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2F_DMNdW8GGVs%2Fnbt.2023 Authors: Phillip E C Compeau, Pavel A Pevzner & Glenn Tesler A mathematical concept known as a de Bruijn graph turns the formidable challenge of assembling a contiguous genome from billions of short sequencing reads into a tractable computational problem. (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5396973 Tue, 08 Nov 2011 05:00:00 +0100 5396973 http://www.medworm.com/index.php?rid=5396972&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FKbiJrSQsd68%2Fnbt.2044 Nature Biotechnology 29, 986 (2011). doi:10.1038/nbt.2044 Author: Kathy Aschheim (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5396972 Tue, 08 Nov 2011 05:00:00 +0100 5396972 http://www.medworm.com/index.php?rid=5396971&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FW9bglLg_pJI%2Fnbt.2043 Nature Biotechnology 29, 986 (2011). doi:10.1038/nbt.2043 Author: Markus Elsner (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5396971 Tue, 08 Nov 2011 05:00:00 +0100 5396971 http://www.medworm.com/index.php?rid=5396970&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FwhKZSXlGo5M%2Fnbt.2042 Nature Biotechnology 29, 986 (2011). doi:10.1038/nbt.2042 Author: Markus Elsner (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5396970 Tue, 08 Nov 2011 05:00:00 +0100 5396970 http://www.medworm.com/index.php?rid=5396969&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2F-qPPaJuoSAw%2Fnbt.2041 Nature Biotechnology 29, 986 (2011). doi:10.1038/nbt.2041 Author: Craig Mak (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5396969 Tue, 08 Nov 2011 05:00:00 +0100 5396969 http://www.medworm.com/index.php?rid=5396968&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FRpi7HOqgPQQ%2Fnbt.2040 Nature Biotechnology 29, 986 (2011). doi:10.1038/nbt.2040 Author: Laura DeFrancesco (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5396968 Tue, 08 Nov 2011 05:00:00 +0100 5396968 http://www.medworm.com/index.php?rid=5396967&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FZBZJLIczidE%2Fnbt.2025 Authors: Todd Shelly & Don McInnis Results from the first open-field trial of transgenic mosquitoes bode well for large-scale releases to fight infectious diseases. (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5396967 Tue, 08 Nov 2011 05:00:00 +0100 5396967 http://www.medworm.com/index.php?rid=5396966&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FZFKC-wanBdg%2Fnbt.2032 Authors: Steven E Bosinger, Zachary P Johnson & Guido Silvestri Genome sequences are now available for two macaque species used in infectious disease research and drug safety testing. (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5396966 Tue, 08 Nov 2011 05:00:00 +0100 5396966 http://www.medworm.com/index.php?rid=5396965&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2F2ZkYezmiRHY%2Fnbt.2021 Authors: Chao Zhang, Gaston Habets & Gideon Bollag Comprehensive studies of the kinome set the stage for discovering the next generation of kinase-directed drugs. (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5396965 Tue, 08 Nov 2011 05:00:00 +0100 5396965 http://www.medworm.com/index.php?rid=5396964&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FHtANVK2-Uz8%2Fnbt.2039 Nature Biotechnology 29, 979 (2011). doi:10.1038/nbt.2039 Author: Julien Muzard (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5396964 Tue, 08 Nov 2011 05:00:00 +0100 5396964 http://www.medworm.com/index.php?rid=5396963&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2Fi43aVTbybtQ%2Fnbt.2026 Authors: Myriam M Altamirano-Bustamante, Adalberto de Hoyos & León Olivé The development of original research requires tacit as well as explicit knowledge, which allows for the establishment of new epistemic trajectories with novel epistemic horizons. Much of the tacit knowledge involved in the innovation process can be transmitted as explicit knowledge through the patent document. (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5396963 Tue, 08 Nov 2011 05:00:00 +0100 5396963 http://www.medworm.com/index.php?rid=5396962&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FEO5MAapVmqE%2Fnbt.2033 Authors: Victor Bethencourt & Christopher Scott Affymetrix was an early mover in the DNA microarray space that came to dominate the market, overcoming criticism from its users and a slew of cutthroat competitors. How did it do it? (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5396962 Tue, 08 Nov 2011 05:00:00 +0100 5396962 http://www.medworm.com/index.php?rid=5396961&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2Fn0W1_mn8060%2Fnbt.2028 Authors: Enis Afgan, Dannon Baker, Nate Coraor, Hiroki Goto, Ian M Paul, Kateryna D Makova, Anton Nekrutenko & James Taylor (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5396961 Tue, 08 Nov 2011 05:00:00 +0100 5396961 http://www.medworm.com/index.php?rid=5396960&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FORa1kfbRSoI%2Fnbt.2027 Authors: Henry I Miller & Drew L Kershen (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5396960 Tue, 08 Nov 2011 05:00:00 +0100 5396960 http://www.medworm.com/index.php?rid=5396958&cid=s_32086_70_f&fid=32086&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fnbt%2Frss%2Fcurrent%2F%7E3%2FwV8Al__gHZc%2Fnbt.2031 Nature Biotechnology 29, 963 (2011). doi:10.1038/nbt.2031 Author: Ken Garber Following approval of hepatitis C virus protease inhibitors Incivek and Victrelis, companies are partnering to devise all-oral combination antiviral regimens without interferon α. But the virus is a long way from vanquished. Ken Garber investigates. (Source: Nature Biotechnology) Nature Biotechnology journals http://www.medworm.com/rss/comments.php?id=5396958 Tue, 08 Nov 2011 05:00:00 +0100 5396958