Nature Immunology via MedWorm.com MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Nature Immunology' source. Wed, 08 Feb 2012 06:43:02 +0100 Corrigendum: STING-dependent signaling http://www.medworm.com/index.php?rid=5607675&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FvbOQI0kY8z8%2Fni0212-196c Nature Immunology 13, 196 (2012). doi:10.1038/ni0212-196c Author: Glen N Barber (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5607675 Thu, 19 Jan 2012 05:00:00 +0100 5607675 Corrigendum: The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells http://www.medworm.com/index.php?rid=5607674&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FdlISa4zUEfw%2Fni0212-196b Nature Immunology 13, 196 (2012). doi:10.1038/ni0212-196b Author: Zhiqiang Zhang, Bin Yuan, Musheng Bao, Ning Lu, Taeil Kim & Yong-Jun Liu (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5607674 Thu, 19 Jan 2012 05:00:00 +0100 5607674 Corrigendum: Endocytosed BCRs sequentially regulate MAPK and Akt signaling pathways from intracellular compartments http://www.medworm.com/index.php?rid=5607673&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FtyJzSzmFKRs%2Fni0212-196a Nature Immunology 13, 196 (2012). doi:10.1038/ni0212-196a Author: Akanksha Chaturvedi, Rebecca Martz, David Dorward, Michael Waisberg & Susan K Pierce (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5607673 Thu, 19 Jan 2012 05:00:00 +0100 5607673 How the TCR balances sensitivity and specificity for the recognition of self and pathogens http://www.medworm.com/index.php?rid=5607664&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FN7RglXrOjck%2Fni.2190 Authors: Gerald P Morris & Paul M Allen (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5607664 Thu, 19 Jan 2012 05:00:00 +0100 5607664 Sec22b in cross-presentation http://www.medworm.com/index.php?rid=5607663&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FDG6s72OnGQw%2Fni.2221 Nature Immunology 13, 120 (2012). doi:10.1038/ni.2221 Author: Laurie A. Dempsey (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5607663 Thu, 19 Jan 2012 05:00:00 +0100 5607663 Inhibiting ubiquitin sensing http://www.medworm.com/index.php?rid=5607662&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FtCForfMQI8A%2Fni.2220 Nature Immunology 13, 120 (2012). doi:10.1038/ni.2220 Author: Laurie A. Dempsey (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5607662 Thu, 19 Jan 2012 05:00:00 +0100 5607662 Erythropoiesis regulator http://www.medworm.com/index.php?rid=5607661&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2F8Ew7owo6Py8%2Fni.2219 Nature Immunology 13, 120 (2012). doi:10.1038/ni.2219 Author: Ioana Visan (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5607661 Thu, 19 Jan 2012 05:00:00 +0100 5607661 Asymmetric division http://www.medworm.com/index.php?rid=5607660&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FCab4ZO00f8Q%2Fni.2218 Nature Immunology 13, 120 (2012). doi:10.1038/ni.2218 Author: Ioana Visan (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5607660 Thu, 19 Jan 2012 05:00:00 +0100 5607660 T cell timing http://www.medworm.com/index.php?rid=5607659&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FChhOmV2jMus%2Fni.2217 Nature Immunology 13, 120 (2012). doi:10.1038/ni.2217 Author: Zoltan Fehervari (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5607659 Thu, 19 Jan 2012 05:00:00 +0100 5607659 Spicing up immunity http://www.medworm.com/index.php?rid=5607658&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2F7s_yzzjaxGI%2Fni.2216 Nature Immunology 13, 120 (2012). doi:10.1038/ni.2216 Author: Zoltan Fehervari (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5607658 Thu, 19 Jan 2012 05:00:00 +0100 5607658 You AhR what you eat? http://www.medworm.com/index.php?rid=5607657&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2F2nnMpSPAtAc%2Fni.2213 Authors: B Paige Lawrence & David H Sherr AhR is more than just a receptor for pollutants. Studies have now identified crucial roles for this environment-sensing transcription factor in the development and maintenance of gut-associated lymphoid tissues. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5607657 Thu, 19 Jan 2012 05:00:00 +0100 5607657 Cellular teamwork in antibacterial innate immunity http://www.medworm.com/index.php?rid=5607656&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FFRSz_nw2ujc%2Fni.2212 Authors: Janelle S Ayres & Russell E Vance IFN-γ is a cytokine that is critical for defense against intracellular bacterial pathogens. New work provides evidence that the recognition of bacterial flagellin by the NLRC4 inflammasome in splenic dendritic cells triggers rapid release of IL-18, which leads to IFN-γ production by memory CD8+ T cells. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5607656 Thu, 19 Jan 2012 05:00:00 +0100 5607656 A new therapeutic strategy for malaria: targeting T cell exhaustion http://www.medworm.com/index.php?rid=5607655&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2F7ubM2hn6UOg%2Fni.2211 Authors: Gordon J Freeman & Arlene H Sharpe Boosting immune responses during malaria remains a challenge. Overcoming T cell exhaustion by blocking coinhibitory receptors offers a promising lead. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5607655 Thu, 19 Jan 2012 05:00:00 +0100 5607655 A helping hand from neutrophils in T cell–independent antibody responses? http://www.medworm.com/index.php?rid=5607654&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FoJyqPa0HiAI%2Fni.2214 A helping hand from neutrophils in T cell–independent antibody responses? Nature Immunology 13, 111 (2012). doi:10.1038/ni.2214 Authors: Stuart G Tangye & Robert Brink Neutrophils and B cells are thought to specialize in driving innate and adaptive immune responses to infection. New data suggest that these cells may also communicate in the splenic marginal zone to drive T cell–independent antibody responses. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5607654 Thu, 19 Jan 2012 05:00:00 +0100 5607654 Immuno-waste exposure and further management http://www.medworm.com/index.php?rid=5607653&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FZD090SrgjOk%2Fni.2204 Authors: Robbert M Spaapen & Jacques Neefjes Since the definition of an immunoselective proteasome, the 'immunoproteasome', its function has been heavily disputed. A mouse with complete deficiency in immunoproteasomes has resolved one issue of the adaptation of the immune system to the proteasome but has raised other questions. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5607653 Thu, 19 Jan 2012 05:00:00 +0100 5607653 Writing a first grant proposal http://www.medworm.com/index.php?rid=5607652&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FgEEBge9aEbU%2Fni.2183 Authors: Julian G Cambronero, Lee-Ann H Allen, Martha K Cathcart, Louis B Justement, Elizabeth J Kovacs, Kenneth R McLeish & William M Nauseef A workshop organized by the Society for Leukocyte Biology offered advice to young scientists on how to decipher the grant-submission process of the US National Institutes of Health and compose a clear, compelling and fundable grant. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5607652 Thu, 19 Jan 2012 05:00:00 +0100 5607652 Lloyd John Old 1933–2011 http://www.medworm.com/index.php?rid=5607651&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FxkdQz3kVgRI%2Fni.2209 Lloyd John Old 1933–2011 Nature Immunology 13, 103 (2012). doi:10.1038/ni.2209 Author: Mark J Smyth (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5607651 Thu, 19 Jan 2012 05:00:00 +0100 5607651 NLRC4 inflammasomes in dendritic cells regulate noncognate effector function by memory CD8+ T cells http://www.medworm.com/index.php?rid=5607669&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2F2SU3FOJk24I%2Fni.2195 Authors: Andreas Kupz, Greta Guarda, Thomas Gebhardt, Leif E Sander, Kirsty R Short, Dimitri A Diavatopoulos, Odilia L C Wijburg, Hanwei Cao, Jason C Waithman, Weisan Chen, Daniel Fernandez-Ruiz, Paul G Whitney, William R Heath, Roy Curtiss, Jürg Tschopp, Richard A Strugnell & Sammy Bedoui (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5607669 Sun, 08 Jan 2012 05:00:00 +0100 5607669 Signaling via the kinase p38α programs dendritic cells to drive TH17 differentiation and autoimmune inflammation http://www.medworm.com/index.php?rid=5607668&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2Fpi7m4y09R2o%2Fni.2207 Signaling via the kinase p38α programs dendritic cells to drive TH17 differentiation and autoimmune inflammation Nature Immunology 13, 152 (2012). doi:10.1038/ni.2207 Authors: Gonghua Huang, Yanyan Wang, Peter Vogel, Thirumala-Devi Kanneganti, Kinya Otsu & Hongbo Chi (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5607668 Sun, 08 Jan 2012 05:00:00 +0100 5607668 The neuroimmune guidance cue netrin-1 promotes atherosclerosis by inhibiting the emigration of macrophages from plaques http://www.medworm.com/index.php?rid=5607666&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FSTkgxrrRoks%2Fni.2205 Authors: Janine M van Gils, Merran C Derby, Luciana R Fernandes, Bhama Ramkhelawon, Tathagat D Ray, Katey J Rayner, Sajesh Parathath, Emilie Distel, Jessica L Feig, Jacqueline I Alvarez-Leite, Alistair J Rayner, Thomas O McDonald, Kevin D O'Brien, Lynda M Stuart, Edward A Fisher, Adam Lacy-Hulbert & Kathryn J Moore (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5607666 Sun, 08 Jan 2012 05:00:00 +0100 5607666 B cell–helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen http://www.medworm.com/index.php?rid=5607670&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FxZuURixQavk%2Fni.2194 B cell–helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen Nature Immunology 13, 170 (2012). doi:10.1038/ni.2194 Authors: Irene Puga, Montserrat Cols, Carolina M Barra, Bing He, Linda Cassis, Maurizio Gentile, Laura Comerma, Alejo Chorny, Meimei Shan, Weifeng Xu, Giuliana Magri, Daniel M Knowles, Wayne Tam, April Chiu, James B Bussel, Sergi Serrano, José Antonio Lorente, Beatriz Bellosillo, Josep Lloreta, Nuria Juanpere, Francesc Alameda, Teresa Baró, Cristina Díaz de Heredia, Núria Torán, Albert Català, Montserrat Torrebadell, Claudia Fortuny, Victoria Cusí, Carmen Carreras, George A Diaz, J Magarian Blander, Claire-Michèle Farber, Guido Silvestri, Charlotte Cunningham-R... Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5607670 Sun, 25 Dec 2011 05:00:00 +0100 5607670 Mice completely lacking immunoproteasomes show major changes in antigen presentation http://www.medworm.com/index.php?rid=5607665&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FHCMj2g8vbpc%2Fni.2203 Authors: Eleanor Z Kincaid, Jenny W Che, Ian York, Hernando Escobar, Eduardo Reyes-Vargas, Julio C Delgado, Raymond M Welsh, Margaret L Karow, Andrew J Murphy, David M Valenzuela, George D Yancopoulos & Kenneth L Rock (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5607665 Sun, 25 Dec 2011 05:00:00 +0100 5607665 The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-α receptor http://www.medworm.com/index.php?rid=5607671&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FSxIjhwtnKII%2Fni.2193 The thymic epithelial microRNA network elevates the threshold for infection-associated thymic involution via miR-29a mediated suppression of the IFN-α receptor Nature Immunology 13, 181 (2012). doi:10.1038/ni.2193 Authors: Aikaterini S Papadopoulou, James Dooley, Michelle A Linterman, Wim Pierson, Olga Ucar, Bruno Kyewski, Saulius Zuklys, Georg A Hollander, Patrick Matthys, Daniel H D Gray, Bart De Strooper & Adrian Liston (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5607671 Sun, 18 Dec 2011 05:00:00 +0100 5607671 A new synthesis for antibody-mediated immunity http://www.medworm.com/index.php?rid=5514892&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2Fpf3VXF4TtBY%2Fni.2184 Authors: Arturo Casadevall & Liise-anne Pirofski (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5514892 Fri, 16 Dec 2011 05:00:00 +0100 5514892 Gut conversations http://www.medworm.com/index.php?rid=5514891&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FMw4Mee3xP7U%2Fni.2201 Nature Immunology 13, 19 (2012). doi:10.1038/ni.2201 Author: Laurie A. Dempsey (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5514891 Fri, 16 Dec 2011 05:00:00 +0100 5514891 Regulation by proteoglycans http://www.medworm.com/index.php?rid=5514890&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FIGE8_74LgyQ%2Fni.2200 Nature Immunology 13, 19 (2012). doi:10.1038/ni.2200 Author: Laurie A. Dempsey (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5514890 Fri, 16 Dec 2011 05:00:00 +0100 5514890 Autophagy switch http://www.medworm.com/index.php?rid=5514889&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FwRl2c8r7Q2g%2Fni.2199 Nature Immunology 13, 19 (2012). doi:10.1038/ni.2199 Author: Ioana Visan (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5514889 Fri, 16 Dec 2011 05:00:00 +0100 5514889 Traffic control http://www.medworm.com/index.php?rid=5514888&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2Fyzte1qBKCKo%2Fni.2198 Nature Immunology 13, 19 (2012). doi:10.1038/ni.2198 Author: Ioana Visan (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5514888 Fri, 16 Dec 2011 05:00:00 +0100 5514888 Mining antiviral complexity http://www.medworm.com/index.php?rid=5514887&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FKjPmGj-Oemc%2Fni.2197 Nature Immunology 13, 19 (2012). doi:10.1038/ni.2197 Author: Zoltan Fehervari (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5514887 Fri, 16 Dec 2011 05:00:00 +0100 5514887 Platelets hold the fort http://www.medworm.com/index.php?rid=5514886&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FHlVKKOsgU-k%2Fni.2196 Nature Immunology 13, 19 (2012). doi:10.1038/ni.2196 Author: Zoltan Fehervari (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5514886 Fri, 16 Dec 2011 05:00:00 +0100 5514886 Ikaros changes the face of NuRD remodeling http://www.medworm.com/index.php?rid=5514885&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FY8liUFb6Q6Q%2Fni.2191 Authors: Kenneth J Oestreich & Amy S Weinmann The inclusion of the transcription factor Ikaros in the NuRD chromatin-remodeling complex regulates both the targeting and activity of the NuRD complex in lymphocytes, thereby influencing developmental gene-expression programs. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5514885 Fri, 16 Dec 2011 05:00:00 +0100 5514885 Transmigration of effector T lymphocytes: changing the rules http://www.medworm.com/index.php?rid=5514884&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2F4lms2eXkzZI%2Fni.2188 Authors: Gabriela Constantin & Carlo Laudanna The transmigration of effector T lymphocytes is critical to adoptive immune response. The rules for the migration of effector T cells are now reported to be distinct from those that apply to naive and memory T cells. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5514884 Fri, 16 Dec 2011 05:00:00 +0100 5514884 CD169+ macrophages take the bullet http://www.medworm.com/index.php?rid=5514883&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FUerTjgho8RQ%2Fni.2189 Authors: Burkhard Ludewig & Luisa Cervantes-Barragan Lifting the protective shield provided by the type I interferon system selectively in CD169+ splenic macrophages enforces localized viral replication. Such controlled release of virus amplifies adaptive antiviral immune responses. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5514883 Fri, 16 Dec 2011 05:00:00 +0100 5514883 Innate iNKT cell help to B cells: fast but does not last http://www.medworm.com/index.php?rid=5514882&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2F6jmR4SuaJ7Q%2Fni.2186 Authors: Agnès Lehuen & Nicolas Fazilleau Harnessing invariant natural killer T cells can boost various immune responses. Two studies now shed light on the direct interaction between those cells and B cells that induce strong primary B cell responses. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5514882 Fri, 16 Dec 2011 05:00:00 +0100 5514882 4th Aegean Conference on The Crossroads between Innate and Adaptive Immunity http://www.medworm.com/index.php?rid=5514881&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FfgNgPptrLqk%2Fni.2192 Authors: Stephen P Schoenberger, Bali Pulendran & Peter D Katsikis The worlds of innate and adaptive immunity collided pleasantly and productively as investigators from each field met in Mykonos for the 4th Aegean Conference on the Crossroads Between Innate and Adaptive Immunity. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5514881 Fri, 16 Dec 2011 05:00:00 +0100 5514881 Lymphocyte signaling: a Tuscan affair http://www.medworm.com/index.php?rid=5514880&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2F62sT51k_mps%2Fni.2185 Authors: Cosima T Baldari, Oreste Acuto, Facundo Batista, Gary Koretzky & Arthur Weiss At the third of the three-part EMBO Conference series “Signaling in the immune system,” immunologists presented their most recent findings in this rapidly moving field and discussed new questions and emerging trends. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5514880 Fri, 16 Dec 2011 05:00:00 +0100 5514880 Induction of BALT in the absence of IL-17 http://www.medworm.com/index.php?rid=5514879&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FkbsiNOSV7Sk%2Fni.2168 Authors: Javier Rangel-Moreno, Damian M Carragher, Maria de la Luz Garcia-Hernandez, Ji Young Hwang, Kim Kusser, Louise Hartson, Jay K Kolls, Shabaana A Khader & Troy D Randall (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5514879 Fri, 16 Dec 2011 05:00:00 +0100 5514879 Therapeutic blockade of PD-L1 and LAG-3 rapidly clears established blood-stage Plasmodium infection http://www.medworm.com/index.php?rid=5607672&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FNWFofiXmk34%2Fni.2180 Authors: Noah S Butler, Jacqueline Moebius, Lecia L Pewe, Boubacar Traore, Ogobara K Doumbo, Lorraine T Tygrett, Thomas J Waldschmidt, Peter D Crompton & John T Harty (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5607672 Sun, 11 Dec 2011 05:00:00 +0100 5607672 Transendothelial migration of lymphocytes mediated by intraendothelial vesicle stores rather than by extracellular chemokine depots http://www.medworm.com/index.php?rid=5514898&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FsIM5itWFNGU%2Fni.2173 Authors: Ziv Shulman, Shmuel J Cohen, Ben Roediger, Vyacheslav Kalchenko, Rohit Jain, Valentin Grabovsky, Eugenia Klein, Vera Shinder, Liat Stoler-Barak, Sara W Feigelson, Tsipi Meshel, Susanna M Nurmi, Itamar Goldstein, Olivier Hartley, Carl G Gahmberg, Amos Etzioni, Wolfgang Weninger, Adit Ben-Baruch & Ronen Alon (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5514898 Sun, 04 Dec 2011 05:00:00 +0100 5514898 Divergent expression patterns of IL-4 and IL-13 define unique functions in allergic immunity http://www.medworm.com/index.php?rid=5514897&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FyHXTEyzaeYI%2Fni.2182 Authors: Hong-Erh Liang, R Lee Reinhardt, Jennifer K Bando, Brandon M Sullivan, I-Cheng Ho & Richard M Locksley (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5514897 Sun, 04 Dec 2011 05:00:00 +0100 5514897 Invariant natural killer T cells direct B cell responses to cognate lipid antigen in an IL-21-dependent manner http://www.medworm.com/index.php?rid=5514895&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FlVZog5E9NxI%2Fni.2172 Authors: Irah L King, Anne Fortier, Michael Tighe, John Dibble, Gerald F M Watts, Natacha Veerapen, Ann M Haberman, Gurdyal S Besra, Markus Mohrs, Michael B Brenner & Elizabeth A Leadbetter (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5514895 Sun, 27 Nov 2011 05:00:00 +0100 5514895 Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses http://www.medworm.com/index.php?rid=5514894&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2F_DYf15ZR524%2Fni.2166 Authors: Pheh-Ping Chang, Patricia Barral, Jessica Fitch, Alvin Pratama, Cindy S Ma, Axel Kallies, Jennifer J Hogan, Vincenzo Cerundolo, Stuart G Tangye, Robert Bittman, Stephen L Nutt, Robert Brink, Dale I Godfrey, Facundo D Batista & Carola G Vinuesa (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5514894 Sun, 27 Nov 2011 05:00:00 +0100 5514894 AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch http://www.medworm.com/index.php?rid=5607667&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FzLqP9XlNo8o%2Fni.2187 Authors: Jacob S Lee, Marina Cella, Keely G McDonald, Cecilia Garlanda, Gregory D Kennedy, Manabu Nukaya, Alberto Mantovani, Raphael Kopan, Christopher A Bradfield, Rodney D Newberry & Marco Colonna (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5607667 Sun, 20 Nov 2011 05:00:00 +0100 5607667 Principles of dimer-specific gene regulation revealed by a comprehensive characterization of NF-κB family DNA binding http://www.medworm.com/index.php?rid=5514901&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FvZSuP-y5gxQ%2Fni.2151 Principles of dimer-specific gene regulation revealed by a comprehensive characterization of NF-κB family DNA binding Nature Immunology 13, 95 (2012). doi:10.1038/ni.2151 Authors: Trevor Siggers, Abraham B Chang, Ana Teixeira, Daniel Wong, Kevin J Williams, Bilal Ahmed, Jiannis Ragoussis, Irina A Udalova, Stephen T Smale & Martha L Bulyk (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5514901 Sun, 20 Nov 2011 05:00:00 +0100 5514901 Enforced viral replication activates adaptive immunity and is essential for the control of a cytopathic virus http://www.medworm.com/index.php?rid=5514896&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FB65hMnwaAiA%2Fni.2169 Authors: Nadine Honke, Namir Shaabani, Giuseppe Cadeddu, Ursula R Sorg, Dong-Er Zhang, Mirko Trilling, Karin Klingel, Martina Sauter, Reinhard Kandolf, Nicole Gailus, Nico van Rooijen, Christoph Burkart, Stephan E Baldus, Melanie Grusdat, Max Löhning, Hartmut Hengel, Klaus Pfeffer, Masato Tanaka, Dieter Häussinger, Mike Recher, Philipp A Lang & Karl S Lang (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5514896 Sun, 20 Nov 2011 05:00:00 +0100 5514896 The redox-sensitive cation channel TRPM2 modulates phagocyte ROS production and inflammation http://www.medworm.com/index.php?rid=5514893&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FEu0j64-wbEg%2Fni.2171 Authors: Anke Di, Xiao-Pei Gao, Feng Qian, Takeshi Kawamura, Jin Han, Claudie Hecquet, Richard D Ye, Stephen M Vogel & Asrar B Malik (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5514893 Sun, 20 Nov 2011 05:00:00 +0100 5514893 Programmed necrosis: backup to and competitor with apoptosis in the immune system http://www.medworm.com/index.php?rid=5421221&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FgA6RKInOUmI%2Fni.2159 Authors: Jiahuai Han, Chuan-Qi Zhong & Duan-Wu Zhang (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5421221 Wed, 16 Nov 2011 05:00:00 +0100 5421221 Malaria insights http://www.medworm.com/index.php?rid=5421220&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FiGBnbHlWvmw%2Fni.2175 Nature Immunology 12, 1141 (2011). doi:10.1038/ni.2175 Author: Ioana Visan (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5421220 Wed, 16 Nov 2011 05:00:00 +0100 5421220 Control in chronic infections http://www.medworm.com/index.php?rid=5421219&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2F50QuDss_vkc%2Fni.2174 Nature Immunology 12, 1141 (2011). doi:10.1038/ni.2174 Author: Ioana Visan (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5421219 Wed, 16 Nov 2011 05:00:00 +0100 5421219 Mast cells crack down on venom http://www.medworm.com/index.php?rid=5421218&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FzmWDpUsmgKk%2Fni.2177 Nature Immunology 12, 1141 (2011). doi:10.1038/ni.2177 Author: Zoltan Fehervari (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5421218 Wed, 16 Nov 2011 05:00:00 +0100 5421218 Vegetable boost to IELs http://www.medworm.com/index.php?rid=5421217&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2F8N2VOlXFaZ4%2Fni.2176 Nature Immunology 12, 1141 (2011). doi:10.1038/ni.2176 Author: Zoltan Fehervari (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5421217 Wed, 16 Nov 2011 05:00:00 +0100 5421217 Caspase-11 inflammasomes http://www.medworm.com/index.php?rid=5421216&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FnTYWnZBVHmk%2Fni.2179 Nature Immunology 12, 1141 (2011). doi:10.1038/ni.2179 Author: Laurie A. Dempsey (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5421216 Wed, 16 Nov 2011 05:00:00 +0100 5421216 Reorienting the groove http://www.medworm.com/index.php?rid=5421215&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2F3BoHOnBYYjM%2Fni.2178 Nature Immunology 12, 1141 (2011). doi:10.1038/ni.2178 Author: Laurie A. Dempsey (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5421215 Wed, 16 Nov 2011 05:00:00 +0100 5421215 Turning transcription on or off with STAT5: when more is less http://www.medworm.com/index.php?rid=5421214&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FVduEukLkx6I%2Fni.2163 Authors: Michael A Farrar & Lynn M Heltemes Harris The transcription factor STAT5 can activate or repress gene expression depending on whether binding of dimer or tetrameric STAT5 occurs. Tetrameric STAT5 recruits the chromatin modifier Ezh2 to silence gene expression. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5421214 Wed, 16 Nov 2011 05:00:00 +0100 5421214 A rescue gone wrong http://www.medworm.com/index.php?rid=5421213&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FOhZ1Z2h9otA%2Fni.2161 Nature Immunology 12, 1137 (2011). doi:10.1038/ni.2161 Author: Steffen Jung Becoming covered in platelets rescues complement-opsonized blood-borne bacteria from rapid clearance by macrophages and redirects them to dendritic cells. Although this allows priming of T cells and the generation of immune memory, bacteria can exploit this route as a beachhead and disseminate throughout host tissues. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5421213 Wed, 16 Nov 2011 05:00:00 +0100 5421213 Beta-testing NKT cell self-reactivity http://www.medworm.com/index.php?rid=5421212&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FSzG13tKbCq0%2Fni.2162 Authors: Dale I Godfrey, Daniel G Pellicci & Jamie Rossjohn Natural killer T cells (NKT cells) recognize lipid-based antigens presented by CD1d. The mammalian glycolipid β-glucosylceramide, a ubiquitous self antigen for NKT cells, is upregulated by microbial danger signals, which leads to activation of NKT cells in the absence of foreign glycolipid antigen. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5421212 Wed, 16 Nov 2011 05:00:00 +0100 5421212 It takes two to tango: a new couple in the family of ubiquitin-editing complexes http://www.medworm.com/index.php?rid=5421211&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FQGSIsz6irbU%2Fni.2165 Nature Immunology 12, 1133 (2011). doi:10.1038/ni.2165 Author: Ingrid E Wertz Improper termination of inflammatory signals can contribute to tumorigenesis. Cyld and Itch form an ubiquitin-editing complex that cooperatively downregulates the kinase Tak1 and thereby attenuates downstream activation of the transcription factor NF-κB. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5421211 Wed, 16 Nov 2011 05:00:00 +0100 5421211 Provocative exhibits at the Seventeen Gallery http://www.medworm.com/index.php?rid=5421210&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2F8BgNQczCavc%2Fni.2164 Authors: Mahima Swamy & Adrian Hayday Two studies identify a tissue-autonomous innate immune mechanism whereby infection provokes epithelial cells to produce IL-17C that engages an epithelial receptor composed of IL-17RA and IL-17RE chains, which promotes host defense and immune activation. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5421210 Wed, 16 Nov 2011 05:00:00 +0100 5421210 Ralph Steinman 1943–2011 http://www.medworm.com/index.php?rid=5421209&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FqHCuSTq-96A%2Fni.2160 Ralph Steinman 1943–2011 Nature Immunology 12, 1129 (2011). doi:10.1038/ni.2160 Author: Carl Nathan (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5421209 Wed, 16 Nov 2011 05:00:00 +0100 5421209 Immunology in the limelight http://www.medworm.com/index.php?rid=5421208&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2F8XuVt4mu8Js%2Fni.2170 Nature Immunology 12, 1127 (2011). doi:10.1038/ni.2170 With the announcement of the Nobel Prize in physiology or medicine, immunology research is once again in the limelight. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5421208 Wed, 16 Nov 2011 05:00:00 +0100 5421208 Harnessing of the nucleosome-remodeling-deacetylase complex controls lymphocyte development and prevents leukemogenesis http://www.medworm.com/index.php?rid=5514900&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FvljjjboOtRk%2Fni.2150 Authors: Jiangwen Zhang, Audrey F Jackson, Taku Naito, Marei Dose, John Seavitt, Feifei Liu, Elizabeth J Heller, Mariko Kashiwagi, Toshimi Yoshida, Fotini Gounari, Howard T Petrie & Katia Georgopoulos (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5514900 Sun, 13 Nov 2011 05:00:00 +0100 5514900 TGF-β induces the expression of the adaptor Ndfip1 to silence IL-4 production during iTreg cell differentiation http://www.medworm.com/index.php?rid=5514899&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FxpEIoAij3Y0%2Fni.2154 TGF-β induces the expression of the adaptor Ndfip1 to silence IL-4 production during iTreg cell differentiation Nature Immunology 13, 77 (2012). doi:10.1038/ni.2154 Authors: Allison M Beal, Natalia Ramos-Hernández, Chris R Riling, Erin A Nowelsky & Paula M Oliver (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5514899 Sun, 13 Nov 2011 05:00:00 +0100 5514899 Repression of the DNA-binding inhibitor Id3 by Blimp-1 limits the formation of memory CD8+ T cells http://www.medworm.com/index.php?rid=5421231&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FZ7FZlZ1nbFE%2Fni.2153 Authors: Yun Ji, Zoltan Pos, Mahadev Rao, Christopher A Klebanoff, Zhiya Yu, Madhusudhanan Sukumar, Robert N Reger, Douglas C Palmer, Zachary A Borman, Pawel Muranski, Ena Wang, David S Schrump, Francesco M Marincola, Nicholas P Restifo & Luca Gattinoni (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5421231 Sun, 06 Nov 2011 04:00:00 +0100 5421231 The transcriptional regulators Id2 and Id3 control the formation of distinct memory CD8+ T cell subsets http://www.medworm.com/index.php?rid=5421230&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FNRVKaBEk9ws%2Fni.2158 Authors: Cliff Y Yang, J Adam Best, Jamie Knell, Edward Yang, Alison D Sheridan, Adam K Jesionek, Haiyan S Li, Richard R Rivera, Kristin Camfield Lind, Louise M D'Cruz, Stephanie S Watowich, Cornelis Murre & Ananda W Goldrath (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5421230 Sun, 06 Nov 2011 04:00:00 +0100 5421230 The E3 ligase Itch and deubiquitinase Cyld act together to regulate Tak1 and inflammation http://www.medworm.com/index.php?rid=5421225&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FyFeoPn-ouhs%2Fni.2157 Authors: Neesar Ahmed, Minghui Zeng, Indrajit Sinha, Lisa Polin, Wei-Zen Wei, Chozhavendan Rathinam, Richard Flavell, Ramin Massoumi & K Venuprasad (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5421225 Sun, 06 Nov 2011 04:00:00 +0100 5421225 Epigenetic repression of the Igk locus by STAT5-mediated recruitment of the histone methyltransferase Ezh2 http://www.medworm.com/index.php?rid=5421229&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FlopC8qNB86o%2Fni.2136 Authors: Malay Mandal, Sarah E Powers, Mark Maienschein-Cline, Elizabeth T Bartom, Keith M Hamel, Barbara L Kee, Aaron R Dinner & Marcus R Clark (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5421229 Sun, 30 Oct 2011 04:00:00 +0100 5421229 Invariant natural killer T cells recognize lipid self antigen induced by microbial danger signals http://www.medworm.com/index.php?rid=5421228&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FqlSonnx4YbI%2Fni.2143 Authors: Patrick J Brennan, Raju V V Tatituri, Manfred Brigl, Edy Y Kim, Amit Tuli, Joseph P Sanderson, Stephan D Gadola, Fong-Fu Hsu, Gurdyal S Besra & Michael B Brenner (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5421228 Sun, 30 Oct 2011 04:00:00 +0100 5421228 A platelet-mediated system for shuttling blood-borne bacteria to CD8α+ dendritic cells depends on glycoprotein GPIb and complement C3 http://www.medworm.com/index.php?rid=5421227&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2Fp1iPJ9J81Wg%2Fni.2140 A platelet-mediated system for shuttling blood-borne bacteria to CD8α+ dendritic cells depends on glycoprotein GPIb and complement C3 Nature Immunology 12, 1194 (2011). doi:10.1038/ni.2140 Authors: Admar Verschoor, Michael Neuenhahn, Alexander A Navarini, Patricia Graef, Ann Plaumann, Amelie Seidlmeier, Bernhard Nieswandt, Steffen Massberg, Rolf M Zinkernagel, Hans Hengartner & Dirk H Busch (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5421227 Sun, 30 Oct 2011 04:00:00 +0100 5421227 The IκB kinase complex regulates the stability of cytokine-encoding mRNA induced by TLR–IL-1R by controlling degradation of regnase-1 http://www.medworm.com/index.php?rid=5421224&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FQF3Wbb2yfR4%2Fni.2137 The IκB kinase complex regulates the stability of cytokine-encoding mRNA induced by TLR–IL-1R by controlling degradation of regnase-1 Nature Immunology 12, 1167 (2011). doi:10.1038/ni.2137 Authors: Hidenori Iwasaki, Osamu Takeuchi, Shunsuke Teraguchi, Kazufumi Matsushita, Takuya Uehata, Kanako Kuniyoshi, Takashi Satoh, Tatsuya Saitoh, Mutsuyoshi Matsushita, Daron M Standley & Shizuo Akira (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5421224 Sun, 30 Oct 2011 04:00:00 +0100 5421224 Expression of A20 by dendritic cells preserves immune homeostasis and prevents colitis and spondyloarthritis http://www.medworm.com/index.php?rid=5421226&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2Ftge_PU26Ibs%2Fni.2135 Authors: Gianna Elena Hammer, Emre E Turer, Kimberly E Taylor, Celia J Fang, Rommel Advincula, Shigeru Oshima, Julio Barrera, Eric J Huang, Baidong Hou, Barbara A Malynn, Boris Reizis, Anthony DeFranco, Lindsey A Criswell, Mary C Nakamura & Averil Ma (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5421226 Sun, 23 Oct 2011 04:00:00 +0100 5421226 Phenotypic and functional plasticity of cells of innate immunity: macrophages, mast cells and neutrophils http://www.medworm.com/index.php?rid=5334748&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FmRS88z7Rdd0%2Fni.2109 Authors: Stephen J Galli, Niels Borregaard & Thomas A Wynn (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5334748 Wed, 19 Oct 2011 04:00:00 +0100 5334748 Inflammasome receptors http://www.medworm.com/index.php?rid=5334747&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FUrJfaQuqDAU%2Fni.2145 Nature Immunology 12, 1033 (2011). doi:10.1038/ni.2145 Author: Ioana Visan (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5334747 Wed, 19 Oct 2011 04:00:00 +0100 5334747 Lineage priming http://www.medworm.com/index.php?rid=5334746&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2F8Ga82wTWj1w%2Fni.2144 Nature Immunology 12, 1033 (2011). doi:10.1038/ni.2144 Author: Ioana Visan (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5334746 Wed, 19 Oct 2011 04:00:00 +0100 5334746 Distributed memory http://www.medworm.com/index.php?rid=5334745&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2F5qK60EeMIYQ%2Fni.2148 Nature Immunology 12, 1033 (2011). doi:10.1038/ni.2148 Author: Zoltan Fehervari (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5334745 Wed, 19 Oct 2011 04:00:00 +0100 5334745 Autoimmunity and PTPN22 http://www.medworm.com/index.php?rid=5334744&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FWKKfb8HXBA8%2Fni.2146 Nature Immunology 12, 1033 (2011). doi:10.1038/ni.2146 Author: Zoltan Fehervari (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5334744 Wed, 19 Oct 2011 04:00:00 +0100 5334744 Neural-iNKT communication http://www.medworm.com/index.php?rid=5334743&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2F_hv8BMV3_vM%2Fni.2149 Nature Immunology 12, 1033 (2011). doi:10.1038/ni.2149 Author: Laurie A. Dempsey (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5334743 Wed, 19 Oct 2011 04:00:00 +0100 5334743 Primitive gut interactions http://www.medworm.com/index.php?rid=5334742&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FYEt-eUsdJNI%2Fni.2147 Nature Immunology 12, 1033 (2011). doi:10.1038/ni.2147 Author: Laurie A. Dempsey (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5334742 Wed, 19 Oct 2011 04:00:00 +0100 5334742 PKC-θ: hitting the bull's eye http://www.medworm.com/index.php?rid=5334741&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FGNkVGYGH-As%2Fni.2141 PKC-θ: hitting the bull's eye Nature Immunology 12, 1031 (2011). doi:10.1038/ni.2141 Author: Michael L Dustin How the kinase PKC-θ is targeted to the immunological synapse and is activated once there remains unclear. A targeting motif in PKC-θ and the previously unsuspected kinase GLK identified in two separate papers now explains this. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5334741 Wed, 19 Oct 2011 04:00:00 +0100 5334741 Don't move: LRRK2 arrests NFAT in the cytoplasm http://www.medworm.com/index.php?rid=5334740&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FSqRQeuAVqwg%2Fni.2139 Authors: Bana Jabri & Luis B Barreiro The kinase LRRK2 is a risk factor for inflammatory bowel disease. New data show that LRRK2 blocks the transport of NFAT to the nucleus and that LRRK2 deficiency results in enhanced susceptibility to experimental colitis in mice. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5334740 Wed, 19 Oct 2011 04:00:00 +0100 5334740 TL we meet again http://www.medworm.com/index.php?rid=5334739&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FvmkvxWejAXA%2Fni.2138 Authors: Cathryn Nagler & Joanna Wroblewska The MHC class I–like molecule TL selects high-affinity effector memory T cells to man the barriers in the intestinal mucosa. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5334739 Wed, 19 Oct 2011 04:00:00 +0100 5334739 Innate lymphoid cells wield a double-edged sword http://www.medworm.com/index.php?rid=5334738&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FiDUnWqkA6yI%2Fni.2142 Authors: Marsha Wills-Karp & Fred D Finkelman Type 2 cytokine–producing innate lymphoid cells are present in human and mouse lungs, where they contribute to both type 2 immune responses and tissue repair. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5334738 Wed, 19 Oct 2011 04:00:00 +0100 5334738 Effective presentations: tips for success http://www.medworm.com/index.php?rid=5334737&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FLxKntpkGGCA%2Fni.2119 Nature Immunology 12, 1021 (2011). doi:10.1038/ni.2119 Author: Janet P Hafler Presentations are given in a variety of environments, and effective strategies can be used to improve a speaker's presenting skills. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5334737 Wed, 19 Oct 2011 04:00:00 +0100 5334737 Reply to "Failure to detect production of IL-10 by activated human neutrophils" http://www.medworm.com/index.php?rid=5334736&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2Fm17Eb8z03us%2Fni.2132 Reply to "Failure to detect production of IL-10 by activated human neutrophils" Nature Immunology 12, 1018 (2011). doi:10.1038/ni.2132 Authors: Carmela De Santo, Mariolina Salio, Tao Dong, Yoram Reiter & Vincenzo Cerundolo (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5334736 Wed, 19 Oct 2011 04:00:00 +0100 5334736 Failure to detect production of IL-10 by activated human neutrophils http://www.medworm.com/index.php?rid=5334735&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FOw2iTGIegms%2Fni.2111 Authors: Martin S Davey, Nicola Tamassia, Marzia Rossato, Flavia Bazzoni, Federica Calzetti, Kirsten Bruderek, Marina Sironi, Lisa Zimmer, Barbara Bottazzi, Alberto Mantovani, Sven Brandau, Bernhard Moser, Matthias Eberl & Marco A Cassatella (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5334735 Wed, 19 Oct 2011 04:00:00 +0100 5334735 Transcription factor c-Maf mediates the TGF-β-dependent suppression of IL-22 production in TH17 cells http://www.medworm.com/index.php?rid=5421232&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2Fo-VoUZAcCJQ%2Fni.2134 Transcription factor c-Maf mediates the TGF-β-dependent suppression of IL-22 production in TH17 cells Nature Immunology 12, 1238 (2011). doi:10.1038/ni.2134 Authors: Sascha Rutz, Rajkumar Noubade, Céline Eidenschenk, Naruhisa Ota, Wenwen Zeng, Yan Zheng, Jason Hackney, Jiabing Ding, Harinder Singh & Wenjun Ouyang (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5421232 Sun, 16 Oct 2011 04:00:00 +0100 5421232 IL-17C regulates the innate immune function of epithelial cells in an autocrine manner http://www.medworm.com/index.php?rid=5421223&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FoF52BntpbaI%2Fni.2156 Authors: Vladimir Ramirez-Carrozzi, Arivazhagan Sambandam, Elizabeth Luis, Zhongua Lin, Surinder Jeet, Justin Lesch, Jason Hackney, Janice Kim, Meijuan Zhou, Joyce Lai, Zora Modrusan, Tao Sai, Wyne Lee, Min Xu, Patrick Caplazi, Lauri Diehl, Jason de Voss, Mercedesz Balazs, Lino Gonzalez, Harinder Singh, Wenjun Ouyang & Rajita Pappu (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5421223 Wed, 12 Oct 2011 04:00:00 +0100 5421223 IL-17RE is the functional receptor for IL-17C and mediates mucosal immunity to infection with intestinal pathogens http://www.medworm.com/index.php?rid=5421222&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FqsbA6Zgz26M%2Fni.2155 Authors: Xinyang Song, Shu Zhu, Peiqing Shi, Yan Liu, Yufang Shi, Steven D Levin & Youcun Qian (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5421222 Wed, 12 Oct 2011 04:00:00 +0100 5421222 The kinase GLK controls autoimmunity and NF-κB signaling by activating the kinase PKC-θ in T cells http://www.medworm.com/index.php?rid=5334757&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2Fmmd4HzW0imo%2Fni.2121 The kinase GLK controls autoimmunity and NF-κB signaling by activating the kinase PKC-θ in T cells Nature Immunology 12, 1113 (2011). doi:10.1038/ni.2121 Authors: Huai-Chia Chuang, Joung-Liang Lan, Der-Yuan Chen, Chia-Yu Yang, Yi-Ming Chen, Ju-Pi Li, Ching-Yu Huang, Pao-En Liu, Xiaohong Wang & Tse-Hua Tan (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5334757 Sun, 09 Oct 2011 04:00:00 +0100 5334757 An IL-9 fate reporter demonstrates the induction of an innate IL-9 response in lung inflammation http://www.medworm.com/index.php?rid=5334752&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FjGrdlJ8VRGs%2Fni.2133 Authors: Christoph Wilhelm, Keiji Hirota, Benjamin Stieglitz, Jacques Van Snick, Mauro Tolaini, Katharina Lahl, Tim Sparwasser, Helena Helmby & Brigitta Stockinger (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5334752 Sun, 09 Oct 2011 04:00:00 +0100 5334752 The kinase LRRK2 is a regulator of the transcription factor NFAT that modulates the severity of inflammatory bowel disease http://www.medworm.com/index.php?rid=5334751&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2Fevjo8kqbmJ8%2Fni.2113 Authors: Zhihua Liu, Jinwoo Lee, Scott Krummey, Wei Lu, Huaibin Cai & Michael J Lenardo (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5334751 Sun, 09 Oct 2011 04:00:00 +0100 5334751 Endocytosed BCRs sequentially regulate MAPK and Akt signaling pathways from intracellular compartments http://www.medworm.com/index.php?rid=5334758&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2Fk7DzVwYSMSg%2Fni.2116 Authors: Akanksha Chaturvedi, Rebecca Martz, David Dorward, Michael Waisberg & Susan K Pierce (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5334758 Sun, 02 Oct 2011 04:00:00 +0100 5334758 A motif in the V3 domain of the kinase PKC-θ determines its localization in the immunological synapse and functions in T cells via association with CD28 http://www.medworm.com/index.php?rid=5334756&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FcXmh6NUQ1Jo%2Fni.2120 A motif in the V3 domain of the kinase PKC-θ determines its localization in the immunological synapse and functions in T cells via association with CD28 Nature Immunology 12, 1105 (2011). doi:10.1038/ni.2120 Authors: Kok-Fai Kong, Tadashi Yokosuka, Ann J Canonigo-Balancio, Noah Isakov, Takashi Saito & Amnon Altman (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5334756 Sun, 02 Oct 2011 04:00:00 +0100 5334756 Mucosal memory CD8+ T cells are selected in the periphery by an MHC class I molecule http://www.medworm.com/index.php?rid=5334754&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FJJU1E-mvQos%2Fni.2106 Authors: Yujun Huang, Yunji Park, Yiran Wang-Zhu, Alexandre Larange, Ramon Arens, Iván Bernardo, Danyvid Olivares-Villagómez, Dietmar Herndler-Brandstetter, Ninan Abraham, Beatrix Grubeck-Loebenstein, Stephen P Schoenberger, Luc Van Kaer, Mitchell Kronenberg, Michael A Teitell & Hilde Cheroutre (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5334754 Sun, 02 Oct 2011 04:00:00 +0100 5334754 The carboxypeptidase ACE shapes the MHC class I peptide repertoire http://www.medworm.com/index.php?rid=5334753&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FMRoVZ3SagTk%2Fni.2107 Authors: Xiao Z Shen, Sandrine Billet, Chentao Lin, Derick Okwan-Duodu, Xu Chen, Aron E Lukacher & Kenneth E Bernstein (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5334753 Sun, 02 Oct 2011 04:00:00 +0100 5334753 Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus http://www.medworm.com/index.php?rid=5334749&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FqAA0LnS9TaE%2Fni.2131 Authors: Laurel A Monticelli, Gregory F Sonnenberg, Michael C Abt, Theresa Alenghat, Carly G K Ziegler, Travis A Doering, Jill M Angelosanto, Brian J Laidlaw, Cliff Y Yang, Taheri Sathaliyawala, Masaru Kubota, Damian Turner, Joshua M Diamond, Ananda W Goldrath, Donna L Farber, Ronald G Collman, E John Wherry & David Artis (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5334749 Sun, 25 Sep 2011 04:00:00 +0100 5334749 Malignant pirates of the immune system http://www.medworm.com/index.php?rid=5236409&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FBdXFGpbq4uU%2Fni.2094 Authors: Lixin Rui, Roland Schmitz, Michele Ceribelli & Louis M Staudt (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5236409 Tue, 20 Sep 2011 04:00:00 +0100 5236409 Early steps of HIV-1 infection http://www.medworm.com/index.php?rid=5236408&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FO6ClVtHpyqg%2Fni.2128 Nature Immunology 12, 931 (2011). doi:10.1038/ni.2128 Author: Ioana Visan (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5236408 Tue, 20 Sep 2011 04:00:00 +0100 5236408 The T cell factor http://www.medworm.com/index.php?rid=5236407&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FQum0s5bDTeA%2Fni.2127 Nature Immunology 12, 931 (2011). doi:10.1038/ni.2127 Author: Ioana Visan (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5236407 Tue, 20 Sep 2011 04:00:00 +0100 5236407 Broadly neutralizing flu http://www.medworm.com/index.php?rid=5236406&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FVWRGe4SJd1U%2Fni.2126 Nature Immunology 12, 931 (2011). doi:10.1038/ni.2126 Author: Zoltan Fehervari (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5236406 Tue, 20 Sep 2011 04:00:00 +0100 5236406 HLA-B*27 and HLA-B*57 viral resistance http://www.medworm.com/index.php?rid=5236405&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FV7ynDSnBJTU%2Fni.2125 Nature Immunology 12, 931 (2011). doi:10.1038/ni.2125 Author: Zoltan Fehervari (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5236405 Tue, 20 Sep 2011 04:00:00 +0100 5236405 NO regulation http://www.medworm.com/index.php?rid=5236404&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2Fx1M9mcfEDNk%2Fni.2130 Nature Immunology 12, 931 (2011). doi:10.1038/ni.2130 Author: Laurie A. Dempsey (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5236404 Tue, 20 Sep 2011 04:00:00 +0100 5236404 Balancing acts by HIF http://www.medworm.com/index.php?rid=5236403&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FVwYwsH6x9sg%2Fni.2129 Nature Immunology 12, 931 (2011). doi:10.1038/ni.2129 Author: Laurie A. Dempsey (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5236403 Tue, 20 Sep 2011 04:00:00 +0100 5236403 STING-dependent signaling http://www.medworm.com/index.php?rid=5236402&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2F0MpdU45t_x8%2Fni.2118 Nature Immunology 12, 929 (2011). doi:10.1038/ni.2118 Author: Glen N Barber The sensing of pathogen-associated DNA in the cytoplasm is an important trigger of host-defense responses that include the production of type I interferon. A new study suggests that the DExDc helicase DDX41 may function in dendritic cells as a DNA sensor to activate STING-dependent innate immune responses. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5236402 Tue, 20 Sep 2011 04:00:00 +0100 5236402 Peli1 (rel)ieves autoimmunity http://www.medworm.com/index.php?rid=5236401&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FexGpWVb1j8M%2Fni.2108 Nature Immunology 12, 927 (2011). doi:10.1038/ni.2108 Author: Paul N Moynagh T cell tolerance is essential to the prevention of autoimmunity. The ubiquitin E3 ligase Peli1 acts as a negative regulator of T cell activation and contributes to the maintenance of self-tolerance. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5236401 Tue, 20 Sep 2011 04:00:00 +0100 5236401 Damage control: how HIV survives the editor APOBEC3G http://www.medworm.com/index.php?rid=5236400&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FVgbpvMobGUY%2Fni.2115 Authors: J Ludovic Croxford & Stephan Gasser The antiviral factor APOBEC3G upregulates the expression of ligands for the activating receptor NKG2D via DNA damage induced by the viral protein Vpr in cells infected with human immunodeficiency virus. The virus overcomes greater susceptibility to natural killer cell–mediated lysis by targeting APOBEC3G for degradation. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5236400 Tue, 20 Sep 2011 04:00:00 +0100 5236400 ASCertaining cytoskeletal rearrangements in antigen presentation and migration http://www.medworm.com/index.php?rid=5236399&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FVMhW1k9FtnE%2Fni.2114 Authors: Ioannis Karakasiliotis & Dimitris L Kontoyiannis ASC has emerged as an adaptor for inflammasome sensors in cells of the innate immune response. New inflammasome-independent roles have been identified for ASC in the control of adaptive immunity; these include the post-transcriptional regulation of cytoskeletal rearrangements. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5236399 Tue, 20 Sep 2011 04:00:00 +0100 5236399 ChIP-Seq: technical considerations for obtaining high-quality data http://www.medworm.com/index.php?rid=5236398&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FdUfe7Jyu9ys%2Fni.2117 Authors: Benjamin L Kidder, Gangqing Hu & Keji Zhao (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5236398 Tue, 20 Sep 2011 04:00:00 +0100 5236398 Baruj Benacerraf 1920–2011 http://www.medworm.com/index.php?rid=5236397&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2Fx10wl9UEByI%2Fni.2110 Baruj Benacerraf 1920–2011 Nature Immunology 12, 917 (2011). doi:10.1038/ni.2110 Author: Kenneth L Rock (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5236397 Tue, 20 Sep 2011 04:00:00 +0100 5236397 The lure of reviews http://www.medworm.com/index.php?rid=5236396&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FeDVsJCmGwWo%2Fni.2122 Nature Immunology 12, 915 (2011). doi:10.1038/ni.2122 The powers and perils of review articles for the design and publication of research. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5236396 Tue, 20 Sep 2011 04:00:00 +0100 5236396 Regulated release of nitric oxide by nonhematopoietic stroma controls expansion of the activated T cell pool in lymph nodes http://www.medworm.com/index.php?rid=5334755&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FAY6ejwXU7io%2Fni.2112 Authors: Veronika Lukacs-Kornek, Deepali Malhotra, Anne L Fletcher, Sophie E Acton, Kutlu G Elpek, Prakriti Tayalia, Ai-ris Collier & Shannon J Turley (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5334755 Sun, 18 Sep 2011 04:00:00 +0100 5334755 Human IL-25- and IL-33-responsive type 2 innate lymphoid cells are defined by expression of CRTH2 and CD161 http://www.medworm.com/index.php?rid=5334750&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FgA8G2kq21oA%2Fni.2104 Authors: Jenny M Mjösberg, Sara Trifari, Natasha K Crellin, Charlotte P Peters, Cornelis M van Drunen, Berber Piet, Wytske J Fokkens, Tom Cupedo & Hergen Spits (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5334750 Sun, 11 Sep 2011 04:00:00 +0100 5334750 Notch signaling is necessary for adult, but not fetal, development of RORγt+ innate lymphoid cells http://www.medworm.com/index.php?rid=5236411&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2F2cPwTz3-PnI%2Fni.2105 Notch signaling is necessary for adult, but not fetal, development of RORγt+ innate lymphoid cells Nature Immunology 12, 949 (2011). doi:10.1038/ni.2105 Authors: Cécilie Possot, Sandrine Schmutz, Sylvestre Chea, Laurent Boucontet, Anne Louise, Ana Cumano & Rachel Golub (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5236411 Sun, 11 Sep 2011 04:00:00 +0100 5236411 The inflammasome adaptor ASC regulates the function of adaptive immune cells by controlling Dock2-mediated Rac activation and actin polymerization http://www.medworm.com/index.php?rid=5236418&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2Fdjq0TsykziE%2Fni.2095 Authors: Sirish K Ippagunta, R K Subbarao Malireddi, Patrick J Shaw, Geoffrey A Neale, Lieselotte Vande Walle, Douglas R Green, Yoshinori Fukui, Mohamed Lamkanfi & Thirumala-Devi Kanneganti (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5236418 Sun, 04 Sep 2011 04:00:00 +0100 5236418 Human cytomegalovirus microRNA miR-US4-1 inhibits CD8+ T cell responses by targeting the aminopeptidase ERAP1 http://www.medworm.com/index.php?rid=5236415&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FtBZOkrMMK68%2Fni.2097 Authors: Sungchul Kim, Sanghyun Lee, Jinwook Shin, Youngkyun Kim, Irini Evnouchidou, Donghyun Kim, Young-Kook Kim, Young-Eui Kim, Jin-Hyun Ahn, Stanley R Riddell, Efstratios Stratikos, V Narry Kim & Kwangseog Ahn (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5236415 Sun, 04 Sep 2011 04:00:00 +0100 5236415 Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive bacteria http://www.medworm.com/index.php?rid=5236413&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2Fu-t-xWV5U0E%2Fni.2096 Authors: Yuki Kinjo, Petr Illarionov, José Luis Vela, Bo Pei, Enrico Girardi, Xiangming Li, Yali Li, Masakazu Imamura, Yukihiro Kaneko, Akiko Okawara, Yoshitsugu Miyazaki, Anaximandro Gómez-Velasco, Paul Rogers, Samira Dahesh, Satoshi Uchiyama, Archana Khurana, Kazuyoshi Kawahara, Hasan Yesilkaya, Peter W Andrew, Chi-Huey Wong, Kazuyoshi Kawakami, Victor Nizet, Gurdyal S Besra, Moriya Tsuji, Dirk M Zajonc & Mitchell Kronenberg (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5236413 Sun, 04 Sep 2011 04:00:00 +0100 5236413 The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells http://www.medworm.com/index.php?rid=5236412&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2F85-_1BRE2Ws%2Fni.2091 Authors: Zhiqiang Zhang, Bin Yuan, Musheng Bao, Ning Lu, Taeil Kim & Yong-Jun Liu (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5236412 Sun, 04 Sep 2011 04:00:00 +0100 5236412 The ubiquitin ligase Peli1 negatively regulates T cell activation and prevents autoimmunity http://www.medworm.com/index.php?rid=5236417&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FXA1uyPa7i7I%2Fni.2090 Authors: Mikyoung Chang, Wei Jin, Jae-Hoon Chang, Yichuan Xiao, George C Brittain, Jiayi Yu, Xiaofei Zhou, Yi-Hong Wang, Xuhong Cheng, Pingwei Li, Brian A Rabinovich, Patrick Hwu & Shao-Cong Sun (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5236417 Sun, 28 Aug 2011 04:00:00 +0100 5236417 The antiviral factor APOBEC3G enhances the recognition of HIV-infected primary T cells by natural killer cells http://www.medworm.com/index.php?rid=5236414&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FzLbm5sfM8Tc%2Fni.2087 Authors: Jason M Norman, Michael Mashiba, Lucy A McNamara, Adewunmi Onafuwa-Nuga, Estelle Chiari-Fort, Wenwen Shen & Kathleen L Collins (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5236414 Sun, 28 Aug 2011 04:00:00 +0100 5236414 IL-22 bridges the lymphotoxin pathway with the maintenance of colonic lymphoid structures during infection with Citrobacter rodentium http://www.medworm.com/index.php?rid=5236410&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FKMTMFhdaztA%2Fni.2089 Authors: Naruhisa Ota, Kit Wong, Patricia A Valdez, Yan Zheng, Natasha K Crellin, Lauri Diehl & Wenjun Ouyang (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5236410 Sun, 28 Aug 2011 04:00:00 +0100 5236410 The opposing roles of the transcription factor E2A and its antagonist Id3 that orchestrate and enforce the naive fate of T cells http://www.medworm.com/index.php?rid=5236416&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2F6UpogGzSsqg%2Fni.2086 Authors: Masaki Miyazaki, Richard R Rivera, Kazuko Miyazaki, Yin C Lin, Yasutoshi Agata & Cornelis Murre (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5236416 Sun, 21 Aug 2011 04:00:00 +0100 5236416 NLR functions in plant and animal immune systems: so far and yet so close http://www.medworm.com/index.php?rid=5142850&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2Ft6SdsR901Nk%2Fni.2083 Authors: Takaki Maekawa, Thomas A Kufer & Paul Schulze-Lefert (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5142850 Wed, 17 Aug 2011 23:00:00 +0100 5142850 Keys to β-selection http://www.medworm.com/index.php?rid=5142849&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FUfqjzOdgSKY%2Fni.2103 Keys to β-selection Nature Immunology 12, 816 (2011). doi:10.1038/ni.2103 Author: Laurie A Dempsey (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5142849 Wed, 17 Aug 2011 23:00:00 +0100 5142849 KIR selection of HIV http://www.medworm.com/index.php?rid=5142848&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FaAofHH9Fv_8%2Fni.2102 Nature Immunology 12, 816 (2011). doi:10.1038/ni.2102 Author: Laurie A Dempsey (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5142848 Wed, 17 Aug 2011 23:00:00 +0100 5142848 Innate stimuli integrator http://www.medworm.com/index.php?rid=5142847&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FjOViurCMVk8%2Fni.2101 Nature Immunology 12, 816 (2011). doi:10.1038/ni.2101 Author: Ioana Visan (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5142847 Wed, 17 Aug 2011 23:00:00 +0100 5142847 Link to NF-κB http://www.medworm.com/index.php?rid=5142846&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FjuPa-PzgAJU%2Fni.2100 Link to NF-κB Nature Immunology 12, 816 (2011). doi:10.1038/ni.2100 Author: Ioana Visan (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5142846 Wed, 17 Aug 2011 23:00:00 +0100 5142846 Lung fibroblasts call the shots http://www.medworm.com/index.php?rid=5142845&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FONcsXm_bsFU%2Fni.2099 Nature Immunology 12, 816 (2011). doi:10.1038/ni.2099 Author: Zoltan Fehervari (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5142845 Wed, 17 Aug 2011 23:00:00 +0100 5142845 Putting a KAP on infection http://www.medworm.com/index.php?rid=5142844&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FQeJ5dmodwww%2Fni.2098 Nature Immunology 12, 816 (2011). doi:10.1038/ni.2098 Author: Zoltan Fehervari (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5142844 Wed, 17 Aug 2011 23:00:00 +0100 5142844 IKKα takes control of canonical NF-κB activation http://www.medworm.com/index.php?rid=5142843&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2F-8AZhABmwhA%2Fni.2082 IKKα takes control of canonical NF-κB activation Nature Immunology 12, 815 (2011). doi:10.1038/ni.2082 Authors: Christiane Pelzer & Margot Thome The kinase IKKα has a well-described activating role in the noncanonical transcription factor NF-κB pathway. Evidence now suggests that IKKα also inhibits the canonical NF-κB pathway by phosphorylating the scaffold protein TAX1BP1 to promote the assembly of the A20 ubiquitin-editing complex. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5142843 Wed, 17 Aug 2011 23:00:00 +0100 5142843 IL-17R signaling: new players get in on the Act1 http://www.medworm.com/index.php?rid=5142842&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FBzBTuV4hEX4%2Fni.2093 Nature Immunology 12, 813 (2011). doi:10.1038/ni.2093 Author: Michael J May Proinflammatory signaling by the interleukin 17 receptor requires the adaptor Act1. Two studies identify an additional function for Act1 and identify new participants that regulate the inflammatory effects of IL-17. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5142842 Wed, 17 Aug 2011 23:00:00 +0100 5142842 A 'Tsc, Tsc' keeps the kids quie(scen)t and holds down ROS http://www.medworm.com/index.php?rid=5142841&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2F4cfzXlaS9wI%2Fni.2092 Authors: Mark Boothby & Keunwook Lee Tuberins, the tumor-suppressor proteins that regulate signaling via the kinase mTOR, now emerge as essential enforcers of T cell quiescence that promote survival. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5142841 Wed, 17 Aug 2011 23:00:00 +0100 5142841 IDO: more than an enzyme http://www.medworm.com/index.php?rid=5142840&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FA25m1NF52AI%2Fni.2088 Nature Immunology 12, 809 (2011). doi:10.1038/ni.2088 Author: WanJun Chen In addition to its recognized function as an enzyme that catalyzes tryptophan, indoleamine 2,3-dioxygenase (IDO) acts as an intracellular signal transducer, in response to transforming growth factor-β (TGF-β), to induce a stably regulatory phenotype in plasmacytoid dendritic cells. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5142840 Wed, 17 Aug 2011 23:00:00 +0100 5142840 Toll2011 at Lago di Garda: studying danger sensors by the guard towers at the lake http://www.medworm.com/index.php?rid=5142839&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FoF0kmxljNQg%2Fni.0911-805 Authors: Søren R Paludan, Ofer Levy & Andrew G Bowie (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5142839 Wed, 17 Aug 2011 23:00:00 +0100 5142839 Repression of the genome organizer SATB1 in regulatory T cells is required for suppressive function and inhibition of effector differentiation http://www.medworm.com/index.php?rid=5142859&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FEqp6DG2kwKQ%2Fni.2084 Authors: Marc Beyer, Yasser Thabet, Roman-Ulrich Müller, Timothy Sadlon, Sabine Classen, Katharina Lahl, Samik Basu, Xuyu Zhou, Samantha L Bailey-Bucktrout, Wolfgang Krebs, Eva A Schönfeld, Jan Böttcher, Tatiana Golovina, Christian T Mayer, Andrea Hofmann, Daniel Sommer, Svenja Debey-Pascher, Elmar Endl, Andreas Limmer, Keli L Hippen, Bruce R Blazar, Robert Balderas, Thomas Quast, Andreas Waha, Günter Mayer, Michael Famulok, Percy A Knolle, Claudia Wickenhauser, Waldemar Kolanus, Bernhard Schermer, Jeffrey A Bluestone, Simon C Barry, Tim Sparwasser, James L Riley & Joachim L Schultze (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5142859 Sat, 13 Aug 2011 23:00:00 +0100 5142859 Afferent lymph–derived T cells and DCs use different chemokine receptor CCR7–dependent routes for entry into the lymph node and intranodal migration http://www.medworm.com/index.php?rid=5142857&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FAmkOoSBpYmE%2Fni.2085 Afferent lymph–derived T cells and DCs use different chemokine receptor CCR7–dependent routes for entry into the lymph node and intranodal migration Nature Immunology 12, 879 (2011). doi:10.1038/ni.2085 Authors: Asolina Braun, Tim Worbs, G Leandros Moschovakis, Stephan Halle, Katharina Hoffmann, Jasmin Bölter, Anika Münk & Reinhold Förster (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5142857 Sat, 13 Aug 2011 23:00:00 +0100 5142857 Treatment with IL-17 prolongs the half-life of chemokine CXCL1 mRNA via the adaptor TRAF5 and the splicing-regulatory factor SF2 (ASF) http://www.medworm.com/index.php?rid=5142854&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2F4Y0hGghUYzo%2Fni.2081 Authors: Dongxu Sun, Michael Novotny, Katarzyna Bulek, Caini Liu, Xiaoxia Li & Thomas Hamilton (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5142854 Sat, 06 Aug 2011 23:00:00 +0100 5142854 The inducible kinase IKKi is required for IL-17-dependent signaling associated with neutrophilia and pulmonary inflammation http://www.medworm.com/index.php?rid=5142853&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FiaUu2PKP0Do%2Fni.2080 Authors: Katarzyna Bulek, Caini Liu, Shadi Swaidani, Liwen Wang, Richard C Page, Muhammet F Gulen, Tomasz Herjan, Amina Abbadi, Wen Qian, Dongxu Sun, Mark Lauer, Vincent Hascall, Saurav Misra, Mark Chance, Mark Aronica, Thomas Hamilton & Xiaoxia Li (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5142853 Sat, 06 Aug 2011 23:00:00 +0100 5142853 Autocrine IL-2 is required for secondary population expansion of CD8+ memory T cells http://www.medworm.com/index.php?rid=5142860&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FYDwynHKTfqE%2Fni.2079 Authors: Sonia Feau, Ramon Arens, Susan Togher & Stephen P Schoenberger (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5142860 Sat, 30 Jul 2011 23:00:00 +0100 5142860 Indoleamine 2,3-dioxygenase is a signaling protein in long-term tolerance by dendritic cells http://www.medworm.com/index.php?rid=5142856&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FsDT1Ke0ht6k%2Fni.2077 Authors: Maria T Pallotta, Ciriana Orabona, Claudia Volpi, Carmine Vacca, Maria L Belladonna, Roberta Bianchi, Giuseppe Servillo, Cinzia Brunacci, Mario Calvitti, Silvio Bicciato, Emilia M C Mazza, Louis Boon, Fabio Grassi, Maria C Fioretti, Francesca Fallarino, Paolo Puccetti & Ursula Grohmann (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5142856 Sat, 30 Jul 2011 23:00:00 +0100 5142856 Recognition of β-linked self glycolipids mediated by natural killer T cell antigen receptors http://www.medworm.com/index.php?rid=5142851&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2Ff133CEetKLg%2Fni.2076 Recognition of β-linked self glycolipids mediated by natural killer T cell antigen receptors Nature Immunology 12, 827 (2011). doi:10.1038/ni.2076 Authors: Daniel G Pellicci, Andrew J Clarke, Onisha Patel, Thierry Mallevaey, Travis Beddoe, Jérôme Le Nours, Adam P Uldrich, James McCluskey, Gurdyal S Besra, Steven A Porcelli, Laurent Gapin, Dale I Godfrey & Jamie Rossjohn (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5142851 Sat, 30 Jul 2011 23:00:00 +0100 5142851 The microRNA miR-29 controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-γ http://www.medworm.com/index.php?rid=5142855&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FhM8i3ryNB8M%2Fni.2073 The microRNA miR-29 controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-γ Nature Immunology 12, 861 (2011). doi:10.1038/ni.2073 Authors: Feng Ma, Sheng Xu, Xingguang Liu, Qian Zhang, Xiongfei Xu, Mofang Liu, Minmin Hua, Nan Li, Hangping Yao & Xuetao Cao (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5142855 Sat, 23 Jul 2011 23:00:00 +0100 5142855 Defeating sepsis by misleading MyD88 http://www.medworm.com/index.php?rid=5052081&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FZz61pqp4uSo%2Fni0811-804b Nature Immunology 12, 804 (2011). doi:10.1038/ni0811-804b Author: Katherine A Smith & Rick M Maizels (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5052081 Mon, 18 Jul 2011 23:00:00 +0100 5052081 The helminth product ES-62 protects against septic shock via Toll-like receptor 4–dependent autophagosomal degradation of the adaptor MyD88 http://www.medworm.com/index.php?rid=5052080&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FyZY6xEohFto%2Fni0811-804a The helminth product ES-62 protects against septic shock via Toll-like receptor 4–dependent autophagosomal degradation of the adaptor MyD88 Nature Immunology 12, 804 (2011). doi:10.1038/ni0811-804a Author: Padmam Puneet, Mairi A McGrath, Hwee Kee Tay, Lamyaa Al-Riyami, Justyna Rzepecka, Shabbir M Moochhala, Shazib Pervaiz, Margaret M Harnett, William Harnett & Alirio J Melendez (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5052080 Mon, 18 Jul 2011 23:00:00 +0100 5052080 Research Highlights http://www.medworm.com/index.php?rid=5052071&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FQoa8rBe98K4%2Fni0811-732 Nature Immunology 12, 732 (2011). doi:10.1038/ni0811-732 (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5052071 Mon, 18 Jul 2011 23:00:00 +0100 5052071 Solving vaccine mysteries: a systems biology perspective http://www.medworm.com/index.php?rid=5052070&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2F-OohXD_i0kI%2Fni.2078 Authors: Lydie Trautmann & Rafick-Pierre Sekaly Systems biology has emerged as a promising research strategy that can be applied to vaccine development. This approach can lead to the identification of new mechanisms and predictors of inactivated vaccine immunogenicity. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5052070 Mon, 18 Jul 2011 23:00:00 +0100 5052070 NUR who? An orphan transcription factor holds promise for monomaniacs http://www.medworm.com/index.php?rid=5052069&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FvTh5qPWGZkQ%2Fni.2074 Authors: Derek W Cain & Michael D Gunn The generation of Ly6C− patrolling monocytes requires the transcription factor NR4A1 (Nur77). This finding provides insight into the development and function of these blood-resident cells. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5052069 Mon, 18 Jul 2011 23:00:00 +0100 5052069 SHP works a double shift to control TLR signaling http://www.medworm.com/index.php?rid=5052068&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FpYrmI3fVKFw%2Fni.2075 Nature Immunology 12, 725 (2011). doi:10.1038/ni.2075 Author: Rudi Beyaert Innate immune responses need to be tightly controlled to avoid autoimmune and inflammatory diseases. The atypical orphan nuclear receptor SHP has now been identified as a negative regulator of Toll-like receptor–induced activation of the transcription factor NF-κB. (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5052068 Mon, 18 Jul 2011 23:00:00 +0100 5052068 Research Highlights http://www.medworm.com/index.php?rid=5052067&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FJg0RjUjXDTo%2Fni0811-724 Nature Immunology 12, 724 (2011). doi:10.1038/ni0811-724 (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5052067 Mon, 18 Jul 2011 23:00:00 +0100 5052067 Inflammation meets cancer, with NF-κB as the matchmaker http://www.medworm.com/index.php?rid=5052066&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FtZJp0mCE3cA%2Fni.2060 Inflammation meets cancer, with NF-κB as the matchmaker Nature Immunology 12, 715 (2011). doi:10.1038/ni.2060 Authors: Yinon Ben-Neriah & Michael Karin (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5052066 Mon, 18 Jul 2011 23:00:00 +0100 5052066 Crosstalk in NF-κB signaling pathways http://www.medworm.com/index.php?rid=5052064&cid=s_33189_3_f&fid=33189&url=http%3A%2F%2Ffeeds.nature.com%2F%7Er%2Fni%2Frss%2Fcurrent%2F%7E3%2FRILAgWyZlNM%2Fni.2065 Crosstalk in NF-κB signaling pathways Nature Immunology 12, 695 (2011). doi:10.1038/ni.2065 Authors: Andrea Oeckinghaus, Matthew S Hayden & Sankar Ghosh (Source: Nature Immunology) Nature Immunology journals http://www.medworm.com/rss/comments.php?id=5052064 Mon, 18 Jul 2011 23:00:00 +0100 5052064