MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Neonatology' source. Mon, 06 Feb 2012 17:44:32 +0100 http://www.medworm.com/index.php?rid=5619330&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22248665%26dopt%3DAbstract Conclusions: Preterm lambs were ventilated effectively with HFJV and 5 CMV breaths/min. CMV breath duration did not alter blood gas exchange, ventilation parameters, ex vivo static lung mechanics or markers of lung injury over a 2-hour study, although consistent trends towards increased inflammatory markers with the longer t(I) suggest greater risk of injury. PMID: 22248665 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5619330 Sat, 14 Jan 2012 05:00:00 +0100 5619330 http://www.medworm.com/index.php?rid=5619329&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22248691%26dopt%3DAbstract Conclusions: In ELBW infants, Mg tends to rise initially then stabilize and remain normal thereafter. The effect of antenatal MgSO(4) on magnesium homeostasis requires further study. PMID: 22248691 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5619329 Sat, 14 Jan 2012 05:00:00 +0100 5619329 http://www.medworm.com/index.php?rid=5576901&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22222256%26dopt%3DAbstract Conclusion: The incidence of BPD in our cohort of preterm infants has decreased during the last decade and could be due to the changes in respiratory management. PMID: 22222256 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5576901 Wed, 04 Jan 2012 05:00:00 +0100 5576901 http://www.medworm.com/index.php?rid=5576900&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22222305%26dopt%3DAbstract Conclusion: Using standardised settings and a well-defined region of interest, the calculation of FMBV using PD images is a reproducible method of estimating neonatal regional cerebral perfusion. PMID: 22222305 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5576900 Wed, 04 Jan 2012 05:00:00 +0100 5576900 http://www.medworm.com/index.php?rid=5576899&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22222353%26dopt%3DAbstract Conclusions: The present study shows that measurement of urinary proteins is a powerful and non-invasive method to quantify the effect of PDA on systemic perfusion in preterm infants. Furthermore, NGAL and H-FABP may be used to indicate the necessity of pharmacological or surgical treatment of PDA. PMID: 22222353 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5576899 Wed, 04 Jan 2012 05:00:00 +0100 5576899 http://www.medworm.com/index.php?rid=5558350&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22205207%26dopt%3DAbstract Conclusions: This study presents an evaluation of a new real-time PCR technique that can detect culture-positive sepsis, and suggests that PCR has the potential to detect bacteria in culture-negative samples even after the initiation of intravenous antibiotics. PMID: 22205207 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5558350 Wed, 28 Dec 2011 05:00:00 +0100 5558350 http://www.medworm.com/index.php?rid=5507723&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22156362%26dopt%3DAbstract Authors: Rosychuk RJ, Hudson-Mason A, Lacaze-Masmonteil T PMID: 22156362 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5507723 Fri, 09 Dec 2011 05:00:00 +0100 5507723 http://www.medworm.com/index.php?rid=5507722&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22156712%26dopt%3DAbstract Authors: O'Reilly M Abstract No abstract available. PMID: 22156712 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5507722 Fri, 09 Dec 2011 05:00:00 +0100 5507722 http://www.medworm.com/index.php?rid=5415307&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22085889%26dopt%3DAbstract Conclusions: Our glucose protocol was effective, but hypoglycemia occurred more frequently than in older children reported previously. Potential differences in glucose and insulin metabolism in term neonates appear to justify additional safety approaches, while awaiting further studies assessing the benefits of tight glucose protocols in this population. Meanwhile, we have decreased the initial insulin starting doses in our protocol. PMID: 22085889 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5415307 Sat, 12 Nov 2011 05:00:00 +0100 5415307 http://www.medworm.com/index.php?rid=5415310&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22076409%26dopt%3DAbstract Conclusion: The majority of the children in our population had no impairments. Cerebral palsy was not seen in any of the infants with a grade III hemorrhage. PMID: 22076409 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5415310 Thu, 10 Nov 2011 05:00:00 +0100 5415310 http://www.medworm.com/index.php?rid=5415309&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22076469%26dopt%3DAbstract Conclusions: Treatment with RGZ in early neonatal life does not alter later developmental metabolic programming or lead to an altered metabolic phenotype in the young adult, further re-enforcing the safety of PPARγ agonists as a novel lung-protective strategy. PMID: 22076469 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5415309 Thu, 10 Nov 2011 05:00:00 +0100 5415309 http://www.medworm.com/index.php?rid=5415308&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22076538%26dopt%3DAbstract Conclusions: No clear and consistent effect of octreotide was identified. Pulmonary hypertension was a common problem in this patient group. It is not clear whether or not this was caused or maintained by octreotide treatment. A randomized controlled trial is needed to investigate the safety and usefulness of octreotide. Until then, clinicians should be careful in using octreotide, especially when persistent pulmonary hypertension is present. PMID: 22076538 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5415308 Thu, 10 Nov 2011 05:00:00 +0100 5415308 http://www.medworm.com/index.php?rid=5415314&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22067375%26dopt%3DAbstract Conclusions: Lung lavage with diluted surfactant appeared to improve the clinical outcome in infants with MAS. Given that less than 100 infants were included in the two RCTs, the findings of this study may still be regarded as insufficient evidence. Further research will be needed to confirm the benefit as well as to refine the lavage technique. PMID: 22067375 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5415314 Tue, 08 Nov 2011 05:00:00 +0100 5415314 http://www.medworm.com/index.php?rid=5415313&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22067461%26dopt%3DAbstract Conclusions: In newborn piglets following hypoxia-reoxygenation injury, levosimendan improves cardiac output but has no marked effects in carotid, superior mesenteric and renal perfusion. It appears that various doses of levosimendan increase the cardiac output through different mechanisms. Further investigations are needed to examine the effectiveness of levosimendan as a cardiovascular supportive therapy either alone or in conjunction with other inotropes in asphyxiated neonates. PMID: 22067461 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5415313 Tue, 08 Nov 2011 05:00:00 +0100 5415313 http://www.medworm.com/index.php?rid=5415312&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22067520%26dopt%3DAbstract We report the successful and safe use of levosimendan, a new calcium-sensitizing agent with positive inotropic and vasodilatory action, in 2 critically ill term newborns with acute heart failure and pulmonary hypertension in the absence of any underlying heart malformation and/or previous cardiosurgical procedures. During the neonatal period, levosimendan may represent an ideal drug for immature myocardium characterized by a higher calcium-dependent contractility than in adults. PMID: 22067520 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5415312 Tue, 08 Nov 2011 05:00:00 +0100 5415312 http://www.medworm.com/index.php?rid=5415311&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22067565%26dopt%3DAbstract Authors: Thewissen L, Allegaert K Abstract No abstract available. PMID: 22067565 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5415311 Tue, 08 Nov 2011 05:00:00 +0100 5415311 http://www.medworm.com/index.php?rid=5377696&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21986335%26dopt%3DAbstract Authors: Speer CP, Halliday HL Abstract No abstract available. PMID: 21986335 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5377696 Sat, 05 Nov 2011 14:35:02 +0100 5377696 http://www.medworm.com/index.php?rid=5377695&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21986336%26dopt%3DAbstract In conclusion, characterization of the pathophysiologic basis for such intermittent hypoxic episodes and their consequences during early life is necessary to provide an evidence-based approach to their management. PMID: 21986336 [PubMed - in process] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5377695 Sat, 05 Nov 2011 14:35:02 +0100 5377695 http://www.medworm.com/index.php?rid=5377694&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21986337%26dopt%3DAbstract Authors: Christensen RD Abstract Platelet transfusions were introduced into clinical medicine about 60 years ago when they were shown to reduce the mortality rate of patients with leukemia who were bleeding secondary to hyporegenerative thrombocytopenia. In modern neonatology units, platelet transfusions are integral and indeed lifesaving for some neonates. However, the great majority of platelet transfusions currently administered in neonatal intensive care units (NICUs) are not given in the original paradigm to treat thrombocytopenic hemorrhage, but instead are administered prophylactically with the hope that they will reduce the risk of spontaneous bleeding. Weighing the risks and benefits of platelet transfusion, although imprecise, should be attempted each time a platelet tran... Neonatology journals http://www.medworm.com/rss/comments.php?id=5377694 Sat, 05 Nov 2011 14:35:02 +0100 5377694 http://www.medworm.com/index.php?rid=5377692&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22024688%26dopt%3DAbstract Authors: Obladen M Abstract Before safe artificial nutrition, refrigeration, and microorganisms became known, thrush was a severe and frequently lethal disease in foundling hospitals. Overcrowded and understaffed, these institutions were the ideal breeding ground for this disease. Malnutrition, especially when breastfeeding was denied, contributed to the fatal course. Nosocomial infections and high mortality led to a prejudice against infant hospitals in the late 19th century. Candida albicans was discovered in 1840 when a cooperation at the Paris Foundling Hospital between the Hungarian emigrant David Gruby and the Swede Frederik Berg led to this organism being the first pathogen to be identified. After World War II, Candida infections increased with the use of antibiotics. The di... Neonatology journals http://www.medworm.com/rss/comments.php?id=5377692 Sat, 22 Oct 2011 04:00:00 +0100 5377692 http://www.medworm.com/index.php?rid=5377691&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22024714%26dopt%3DAbstract Conclusion: This study defines normal values for echocardiographic measurements in healthy term infants during the first 4 h after birth. These normative data may be useful in early identification of infants with abnormal circulatory transition, allowing more rapid determination of cardiovascular dysfunction. PMID: 22024714 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5377691 Sat, 22 Oct 2011 04:00:00 +0100 5377691 http://www.medworm.com/index.php?rid=5377690&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22024741%26dopt%3DAbstract Conclusion: MO is not a rare condition in ELBWIs, and the majority of ELBWIs have prenatal risk factors. Medical management was effective, and medically manageable cases had good prognoses for subsequent feeding, whereas some surgically managed cases had persistent gastrointestinal problems. PMID: 22024741 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5377690 Sat, 22 Oct 2011 04:00:00 +0100 5377690 http://www.medworm.com/index.php?rid=5377689&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22024762%26dopt%3DAbstract Conclusions: Our findings suggest: (1) evaluation of PVI values is an easily applicable, noninvasive procedure for monitoring early postnatal respiratory changes in newborns, and (2) the feasibility of a noninvasive pulse-oximeter postnatal screening for early identification of adverse neonatal cardiorespiratory outcomes. PMID: 22024762 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5377689 Sat, 22 Oct 2011 04:00:00 +0100 5377689 http://www.medworm.com/index.php?rid=5377693&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22005450%26dopt%3DAbstract Authors: Sherman MP, Cooperstock MS Abstract No abstract available. PMID: 22005450 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5377693 Tue, 18 Oct 2011 04:00:00 +0100 5377693 http://www.medworm.com/index.php?rid=5294462&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21968165%26dopt%3DAbstract Authors: Rivera JC, Sapieha P, Joyal JS, Duhamel F, Shao Z, Sitaras N, Picard E, Zhou E, Lachapelle P, Chemtob S Abstract Retinopathy of prematurity (ROP), an ocular disease characterized by the onset of vascular abnormalities in the developing retina, is the major cause of visual impairment and blindness in premature neonates. ROP is a complex condition in which various factors participate at different stages of the disease leading to microvascular degeneration followed by neovascularization, which in turn predisposes to retinal detachment. Current ablative therapies (cryotherapy and laser photocoagulation) used in the clinic for the treatment of ROP have limitations and patients can still have long-term effects even after successful treatment. New treatment modalities are still e... Neonatology journals http://www.medworm.com/rss/comments.php?id=5294462 Mon, 03 Oct 2011 04:00:00 +0100 5294462 http://www.medworm.com/index.php?rid=5294461&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21968213%26dopt%3DAbstract Authors: Kaplan M, Bromiker R, Hammerman C Abstract Despite efforts to eliminate permanent and irreversible brain damage due to bilirubin encephalopathy and kernicterus, these conditions continue to accompany us into the third millennium. This phenomenon occurs not only in developing countries with emerging medical systems, but in Westernized countries as well. Comprehensive guidelines to detect newborns with jaundice and treat those in whom hyperbilirubinemia has already developed have been formulated in several countries, but have not been successful in completely eliminating the problem. In this appraisal of the situation we review selected aspects of bilirubin encephalopathy and/or kernicterus. We highlight recent reports of severe hyperbilirubinemia and kernicterus, discuss so... Neonatology journals http://www.medworm.com/rss/comments.php?id=5294461 Mon, 03 Oct 2011 04:00:00 +0100 5294461 http://www.medworm.com/index.php?rid=5294460&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21968248%26dopt%3DAbstract We report a case of a 4-day-old neonate presenting with 18% weight loss, hypernatremic dehydration and metabolic acidosis. Despite aggressive fluid resuscitation (206 ml/kg for the first 24 h), the dehydration and metabolic acidosis were only minimally improved. The diapers were found soaked with clear, non-odorous fluid on repeated examinations. Persistent secretory diarrhea was suspected. Stool electrolytes analyses showed a high NaCl content typical of secretory diarrhea and intestinal biopsy with electron microscopy was diagnostic of MID. PMID: 21968248 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5294460 Fri, 30 Sep 2011 04:00:00 +0100 5294460 http://www.medworm.com/index.php?rid=5273922&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21952491%26dopt%3DAbstract Conclusion: These data suggest that NO-cGMP signaling is disrupted in neonatal rat pups exposed to even moderate hyperoxia due to increased arginase activity and consequent decreased bioavailability of the substrate L-arginine. We speculate that supplementation of arginine and/or inhibition of arginase may be a useful therapeutic tool to prevent or treat neonatal lung injury. PMID: 21952491 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5273922 Fri, 23 Sep 2011 04:00:00 +0100 5273922 http://www.medworm.com/index.php?rid=5273921&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21952518%26dopt%3DAbstract Conclusion: CT-proET-1 is a promising predictor in determining the need for PDA intervention. PMID: 21952518 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5273921 Fri, 23 Sep 2011 04:00:00 +0100 5273921 http://www.medworm.com/index.php?rid=5273920&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21952535%26dopt%3DAbstract Conclusions: Serum CCSP levels were characterized by an early postnatal surge. This apparent gestation-influenced surge may represent an initiation of a protective cascade against postnatal lung injury during extrauterine adaptation. PMID: 21952535 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5273920 Fri, 23 Sep 2011 04:00:00 +0100 5273920 http://www.medworm.com/index.php?rid=5273919&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21952554%26dopt%3DAbstract Conclusions: Lung growth, bronchial innervation and peristalsis are decreased in nitrofen-exposed lung explants and are rescued by RA. If deficient airway innervation contributing to dysmotility and pulmonary hypoplasia can be pharmacologically rescued, new relatively simple prenatal interventions could be envisioned. PMID: 21952554 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5273919 Fri, 23 Sep 2011 04:00:00 +0100 5273919 http://www.medworm.com/index.php?rid=5273918&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21952587%26dopt%3DAbstract Conclusions: These studies provide new insights relevant to the inflammatory biology of neonates, both term and preterm, and implicate exaggerated PMN recruitment in neonatal syndromes of dysregulated inflammation such as necrotizing enterocolitis or neonatal chronic lung disease. PMID: 21952587 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5273918 Fri, 23 Sep 2011 04:00:00 +0100 5273918 http://www.medworm.com/index.php?rid=5273917&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21952615%26dopt%3DAbstract Conclusion: Resuscitation with 100% oxygen compared to room air induces diastolic dysfunction, disrupts the systolic force-frequency relationship and increases myocardial damage in the newborn pig. PMID: 21952615 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5273917 Fri, 23 Sep 2011 04:00:00 +0100 5273917 http://www.medworm.com/index.php?rid=5241971&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21934332%26dopt%3DAbstract Authors: Sun B, Ma L, Liu X, Gao X, Ni L Abstract Recent economic improvements in China have allowed the development of perinatal-neonatal care in sub-provincial regions. However, variations in neonatal respiratory and intensive care exist, especially in regions with limited resources. We conducted a series of collaborative clinical investigations into neonatal hypoxemic respiratory failure (NRF). In the study period from 2004 to 2005, this nationwide study found an incidence of NRF of 13.4% of total admissions to neonatal intensive care units (NICUs), with a mortality of 32%. Fewer than 30% of infants with respiratory distress syndrome (RDS) received surfactant treatment. Most cases of NRF had birth weights (BWs) of 1,000-1,500 g. Approximately 60% of deaths were due to withdrawal... Neonatology journals http://www.medworm.com/rss/comments.php?id=5241971 Sat, 17 Sep 2011 04:00:00 +0100 5241971 http://www.medworm.com/index.php?rid=5241970&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21934333%26dopt%3DAbstract Authors: Williams O, Hutchings G, Hubinont C, Debauche C, Greenough A Abstract Mid-trimester, preterm prelabour rupture of the membranes (PPROM) with prolonged oligohydramnios remains a challenge for both obstetricians and neonatologists. Although survival rates have improved, morbidity remains common particularly due to pulmonary insufficiency and pulmonary hypertension. The aetiology of abnormal lung development is unknown but may depend critically on pulmonary vascular development. Antenatal evaluation of at-risk foetuses by three-dimensional ultrasound and MRI is possible but the techniques need to be further assessed. Antenatal corticosteroids given in cases of PPROM reduce the incidence of neonatal death, respiratory distress syndrome, intraventricular haemorrhage and necroti... Neonatology journals http://www.medworm.com/rss/comments.php?id=5241970 Sat, 17 Sep 2011 04:00:00 +0100 5241970 http://www.medworm.com/index.php?rid=5241969&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21934334%26dopt%3DAbstract Conclusion: Defective platelet plug formation occurs during therapeutic hypothermia of neonates in a manner similar to that described in adults. Platelet impairment can be severe, but rapidly improves after rewarming. PMID: 21934334 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5241969 Sat, 17 Sep 2011 04:00:00 +0100 5241969 http://www.medworm.com/index.php?rid=5241968&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21934335%26dopt%3DAbstract Conclusion: Conventional CPAP generators work more quietly than the currently available jet CPAP generators. PMID: 21934335 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5241968 Sat, 17 Sep 2011 04:00:00 +0100 5241968 http://www.medworm.com/index.php?rid=5241967&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21934336%26dopt%3DAbstract Conclusions: Antibiotic treatment for CoNS sepsis may be shortened to 3 days when clinical improvement is rapid and central lines are not present. Prospective randomized studies are needed to confirm the results of this single-center study. Future studies may reveal the effects on the development of antimicrobial resistance. PMID: 21934336 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5241967 Sat, 17 Sep 2011 04:00:00 +0100 5241967 http://www.medworm.com/index.php?rid=5241972&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21934331%26dopt%3DAbstract Conclusions: During the first month of lactation, the absolute amount of polysaccharides was constantly and significantly higher in preterm than in term milk, with a similar behavior in the decrease. These data further indicate that human milk GAGs may have an active role in protecting newborns during the first phases of lactation. PMID: 21934331 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5241972 Fri, 16 Sep 2011 04:00:00 +0100 5241972 http://www.medworm.com/index.php?rid=5225916&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21912184%26dopt%3DAbstract Conclusion: Although infants with polyhydramnios, but no major congenital malformations, were found to have increased rates of respiratory distress and hypoglycemia, these clinical manifestations were mild and had little effect on the babies' well-being and length of hospital stay. PMID: 21912184 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5225916 Thu, 08 Sep 2011 04:00:00 +0100 5225916 http://www.medworm.com/index.php?rid=5225915&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21912185%26dopt%3DAbstract Conclusion: Neonatal autopsy remains a valuable diagnostic tool as it provides critical clinical and audit information for healthcare professionals and families. PMID: 21912185 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5225915 Thu, 08 Sep 2011 04:00:00 +0100 5225915 http://www.medworm.com/index.php?rid=5092996&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21701201%26dopt%3DAbstract Authors: Ozek E, Curstedt T, Halliday HL, Hallman M, Saugstad OD, Speer CP PMID: 21701201 [PubMed - in process] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092996 Thu, 04 Aug 2011 11:30:09 +0100 5092996 http://www.medworm.com/index.php?rid=5092995&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21701202%26dopt%3DAbstract Authors: Ozek E, Curstedt T, Halliday HL, Hallman M, Saugstad OD, Speer CP PMID: 21701202 [PubMed - in process] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092995 Thu, 04 Aug 2011 11:30:09 +0100 5092995 http://www.medworm.com/index.php?rid=5092994&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21701203%26dopt%3DAbstract Authors: Speer CP Surfactant substitution has been a major breakthrough in the treatment of neonatal respiratory distress syndrome (RDS), primarily caused by a lack of pulmonary surfactant; it has significantly reduced mortality and acute pulmonary morbidity in preterm infants. Some very immature infants, however, have a poor response to surfactant replacement or an early relapse. This brief article is based on the hypothesis that neonatal RDS has a complex and multifactorial pathogenesis characterized by an injurious inflammatory sequence in the immature lung. Fetal exposure to chorioamnionitis has been shown to initiate an inflammatory reaction beginning in utero. A 'low-grade' inflammatory stimulus in utero may 'prime' the fetal lung for accelerated maturation of the surfactant syst... Neonatology journals http://www.medworm.com/rss/comments.php?id=5092994 Thu, 04 Aug 2011 11:30:09 +0100 5092994 http://www.medworm.com/index.php?rid=5092993&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21701204%26dopt%3DAbstract Authors: Kramer BW Antenatal inflammation may be associated with adverse neonatal outcomes in several organ systems. Bacteria and a few viruses have been detected in cases of microbial invasion of the amniotic cavity which is referred to as chorioamnionitis. Many aspects of this disease remain unclear such as the causes, time of onset and the fetal responses. Chorioamnionitis was therefore induced in pregnant sheep by injections of lipopolysaccharide (LPS) or Ureaplasma species into the amniotic cavity under ultrasound guidance. LPS-induced chorioamnionitis caused a cascade of organ injury, inflammation, and remodeling. The organ-specific changes were accompanied by systemic effects. The systemic effects after LPS-induced chorioamnionitis resulted in immune suppression against several ... Neonatology journals http://www.medworm.com/rss/comments.php?id=5092993 Thu, 04 Aug 2011 11:30:09 +0100 5092993 http://www.medworm.com/index.php?rid=5092975&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21701205%26dopt%3DAbstract Authors: Alphonse RS, Thébaud B Bronchopulmonary dysplasia (BPD) is the chronic lung disease of prematurity mainly affecting preterm infants that are born at 24-28 weeks of gestation. Surfactant therapy, antenatal steroids and incremental improvements in perinatal care have modified the pattern of injury and allowed survival of ever more immature infants, but there is still no specific treatment for BPD. As a consequence, this disorder remains the most common complication of extreme prematurity. Arrested alveolar growth and disrupted vasculogenesis, the histological hallmarks of BPD, may persist beyond childhood and lead to chronic lung diseases in adults. Recent advances in our understanding of stem cells and their potential to repair damaged organs offer the possibility for cell-bas... Neonatology journals http://www.medworm.com/rss/comments.php?id=5092975 Thu, 04 Aug 2011 11:30:09 +0100 5092975 http://www.medworm.com/index.php?rid=5092968&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21701206%26dopt%3DAbstract Authors: van Kaam A Ventilator-induced lung injury (VILI) is considered an important risk factor in the development of bronchopulmonary dysplasia (BPD) and is primarily caused by overdistension (volutrauma) and repetitive opening and collapse (atelectrauma) of terminal lung units. Lung-protective ventilation should therefore aim to reduce tidal volumes, and recruit and stabilize atelectatic lung units (open lung ventilation strategy). This review will summarize the available evidence on lung-protective ventilation in neonatology, discussing both high-frequency ventilation (HFV) and positive pressure ventilation (PPV). It shows that HFV does not appear to have a clear benefit over PPV, although most studies failed to apply a true open lung ventilation strategy during HFV. The evidence o... Neonatology journals http://www.medworm.com/rss/comments.php?id=5092968 Thu, 04 Aug 2011 11:30:09 +0100 5092968 http://www.medworm.com/index.php?rid=5092967&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21701207%26dopt%3DAbstract Authors: Vento M Fetal to neonatal transition poses an extraordinary challenge for the extremely low birth weight (ELBW) neonate. Indeed a significant number of ELBW neonates will need proactive resuscitation to achieve postnatal stabilization. Positive pressure ventilation and oxygenation are the most relevant interventions in the delivery room (DR). Oxygen needs during resuscitation still represent a conundrum for neonatologists. While hyperoxemia favors oxidative stress and subsequent organ injury, hypoxemia is associated with long-term neurodevelopmental impairment. It has been shown that ELBW neonates can be successfully resuscitated with lower concentrations of oxygen as had been done traditionally. Moreover, reducing oxygen load has resulted in achievement of arterial partial pr... Neonatology journals http://www.medworm.com/rss/comments.php?id=5092967 Thu, 04 Aug 2011 11:30:09 +0100 5092967 http://www.medworm.com/index.php?rid=5092966&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21701208%26dopt%3DAbstract Authors: Soll RF, Pfister RH The first hour of a newborn's life is fraught with difficulty. Recommendations regarding the fundamental issues of resuscitation of these infants are developed and disseminated by the International Liaison Committee on Resuscitation and other organizations. However, these recommendations frequently do not address the needs of the very low birth weight infant and do not address some of the nuances that might lead to improved outcome. Improved organization and teamwork as well as improved monitoring and respiratory support can potentially improve the outcome of these infants. PMID: 21701208 [PubMed - in process] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092966 Thu, 04 Aug 2011 11:30:09 +0100 5092966 http://www.medworm.com/index.php?rid=5092965&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21701209%26dopt%3DAbstract Conclusions: In developing countries, CPAP may be used as the primary mode of management of RDS. SRT may be reserved for non-responders to CPAP. Alternate simpler methods of delivery of surfactant (aerosol technique) are also being explored. There is a need for further studies to develop and assess efficient and less expensive methods of application of CPAP and SRT in developing countries. PMID: 21701209 [PubMed - in process] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092965 Thu, 04 Aug 2011 11:30:09 +0100 5092965 http://www.medworm.com/index.php?rid=5092937&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21791927%26dopt%3DAbstract Conclusion: Manganese-enhanced MRI can be a useful tool for in vivo identification of cerebral tissue undergoing delayed cell death and liquefaction after HI. Manganese enhancement at a late stage seems to be related to the accumulation of manganese in calcifications and gliotic tissue. PMID: 21791927 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092937 Tue, 26 Jul 2011 23:00:00 +0100 5092937 http://www.medworm.com/index.php?rid=5092929&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21791929%26dopt%3DAbstract Conclusions: In conclusion, IUGR piglets have reduced nephron endowment associated with a modest BP increase in early adulthood. This new model can be used to conduct longitudinal mechanistic studies on the early programming phenomenon. PMID: 21791929 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092929 Tue, 26 Jul 2011 23:00:00 +0100 5092929 http://www.medworm.com/index.php?rid=5092925&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21791930%26dopt%3DAbstract Conclusions: These results indicate that ETH is associated with increased peroxynitrite generation resulting in systemic protein nitration in premature newborns. Treatment of ETH with intravenous dextrose is associated with lower PNA levels than gavage. PMID: 21791930 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092925 Tue, 26 Jul 2011 23:00:00 +0100 5092925 http://www.medworm.com/index.php?rid=5092918&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21791932%26dopt%3DAbstract Conclusions: There is a temporal relationship between the emergence of neonatal GBS disease reports in the UK in the 1960s and a change in cow's milk collection. This finding may be a temporal coincidence or may add support to the notion that human GBS was historically derived from a bovine ancestor. PMID: 21791932 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092918 Tue, 26 Jul 2011 23:00:00 +0100 5092918 http://www.medworm.com/index.php?rid=5092914&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21791933%26dopt%3DAbstract Authors: Merhar S Posthemorrhagic hydrocephalus (PHH) is a rare but serious outcome among premature babies in the NICU, with consequences including mortality and severe neurodevelopmental disabilities. The causes of PHH are still not entirely understood, and its prevention and treatment are controversial. Various cerebrospinal fluid biomarkers have been studied in infants with PHH in order to recognize the causes, diagnose brain injury, and predict neurodevelopmental outcomes. This systematic review summarizes studies on biomarkers of extracellular matrix activity, fibrinolysis/coagulation, hypoxia/cell death, and inflammation in the cerebrospinal fluid of infants with PHH. PMID: 21791933 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092914 Tue, 26 Jul 2011 23:00:00 +0100 5092914 http://www.medworm.com/index.php?rid=5092933&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21791928%26dopt%3DAbstract Conclusions: In VLBW infants, AHT at ≤35.5 and at ≤35.0°C were not significantly associated with IVH. GA, use of nitric oxide, hypocarbia and base deficit >10 were strongly associated with IVH. PMID: 21791928 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092933 Mon, 25 Jul 2011 23:00:00 +0100 5092933 http://www.medworm.com/index.php?rid=5092909&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21791934%26dopt%3DAbstract Authors: Hansen TW Many advances have occurred in clinical medicine in the last decades. Solid organ transplants, corrective surgery for congenital malformations, improved cytostatic regimes for children with cancer, and respiratory care for premature infants are but a few examples of the changing face of medical practice. Such changes have added years to life. But along the way many patients have paid a price, both in terms of loss of life and of added suffering. Even today, some survivors are faced with a life of impairment and suffering. Follow-up studies of extremely low-birth-weight infants show that the smallest infants have a high rate of severe sequelae. Some argue that such suffering should be sufficient reason to make us desist from further attempts to advance the frontiers o... Neonatology journals http://www.medworm.com/rss/comments.php?id=5092909 Mon, 25 Jul 2011 23:00:00 +0100 5092909 http://www.medworm.com/index.php?rid=5092904&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21791935%26dopt%3DAbstract Conclusion: SaO(2) was lower on average than SpO(2) with an increased bias at lower saturation. The -2.4 ± 9.2 95% limits of agreement for SaO(2) - SpO(2) in the 85-89% SpO(2) category suggest that SpO(2) and SaO(2) are not interchangeable and intermittent SaO(2) assessments are warranted when the targeted SpO(2) is within this range. PMID: 21791935 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092904 Mon, 25 Jul 2011 23:00:00 +0100 5092904 http://www.medworm.com/index.php?rid=5092898&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21791936%26dopt%3DAbstract Conclusions: Intravenous indomethacin was followed by a decline in coronary arterial diastolic blood flow. PMID: 21791936 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092898 Mon, 25 Jul 2011 23:00:00 +0100 5092898 http://www.medworm.com/index.php?rid=5092894&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21791937%26dopt%3DAbstract Conclusions: Pulmonary artery dilation to zaprinast supports the use of PDE5 inhibitors to treat pulmonary hypertension in neonates. PDE5 inhibitors function as MCA dilators but do not impair the pressure-diameter behavior of the cerebral circulation of either normoxic newborn piglets or those with chronic hypoxia-induced pulmonary hypertension. These findings suggest that cerebral autoregulation is likely to be intact with acute PDE5 inhibitor treatment in infants with pulmonary hypertension in conditions associated with chronic hypoxia. PMID: 21791937 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092894 Mon, 25 Jul 2011 23:00:00 +0100 5092894 http://www.medworm.com/index.php?rid=5092888&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21791938%26dopt%3DAbstract Conclusions: The present study shows that oligohydramnios is a specific risk factor for PAH in preterm infants with moderate or severe BPD. PMID: 21791938 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092888 Mon, 25 Jul 2011 23:00:00 +0100 5092888 http://www.medworm.com/index.php?rid=5092886&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21791939%26dopt%3DAbstract Conclusions: Local RAS activation is involved in the pathogenesis of hyperoxia-induced lung fibrosis in neonatal rats. ERK phosphorylation might mediate angiotensin II type 1 receptor activation. PMID: 21791939 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092886 Mon, 25 Jul 2011 23:00:00 +0100 5092886 http://www.medworm.com/index.php?rid=5092881&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21791940%26dopt%3DAbstract Conclusion: Neonatal cell-free salivary supernatant mRNA may be readily extracted and utilized on downstream applications. These technical enhancements allow for further exploration of the diagnostic potential of the neonatal salivary transcriptome. PMID: 21791940 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092881 Mon, 25 Jul 2011 23:00:00 +0100 5092881 http://www.medworm.com/index.php?rid=5092849&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21811080%26dopt%3DAbstract Authors: Riede FT, Schneider P No abstract available. PMID: 21811080 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092849 Mon, 25 Jul 2011 23:00:00 +0100 5092849 http://www.medworm.com/index.php?rid=5092844&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21811081%26dopt%3DAbstract Authors: Hoffman JI No abstract available. PMID: 21811081 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092844 Mon, 25 Jul 2011 23:00:00 +0100 5092844 http://www.medworm.com/index.php?rid=5092922&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21791931%26dopt%3DAbstract Conclusion: There are significant differences in the birthweights of White British and UK-born South Asian infants. Hence the standard birthweight centile charts which were designed using the birthweight data of White British infants appear to misclassify a proportion of South Asian infants. Use of ethnic specific birthweight charts would allow better detection of truly growth-restricted and macrosomic South Asian infants. PMID: 21791931 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092922 Sun, 24 Jul 2011 23:00:00 +0100 5092922 http://www.medworm.com/index.php?rid=5092941&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21757963%26dopt%3DAbstract Authors: Saugstad OD, Speer CP, Halliday HL No abstract available. PMID: 21757963 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092941 Thu, 14 Jul 2011 23:00:00 +0100 5092941 http://www.medworm.com/index.php?rid=5092957&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21701217%26dopt%3DAbstract Conclusions: Ventilation with a helium and oxygen mixture had a positive effect on the selected parameters of oxygenation, while its effects on other respiratory parameters were relatively small. PMID: 21701217 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092957 Wed, 22 Jun 2011 23:00:00 +0100 5092957 http://www.medworm.com/index.php?rid=5092956&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21701218%26dopt%3DAbstract Conclusion: Two drugs that block TGFβ by different mechanisms do not reduce ventricular dilatation in this model. Together with our previous work on losartan and pirfenidone, we conclude that blocking TGFβ alone does not prevent the development of PHVD. PMID: 21701218 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092956 Wed, 22 Jun 2011 23:00:00 +0100 5092956 http://www.medworm.com/index.php?rid=5092955&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21701219%26dopt%3DAbstract Authors: Akin MA, Akin L, Coban D, Ozturk MA, Bircan R, Kurtoglu S Familial glucocorticoid deficiency (FGD) or hereditary unresponsiveness to adrenocorticotropin (ACTH) is an autosomal recessive disorder characterized by isolated glucocorticoid deficiency associated with normal mineralocorticoid secretion. Mutations in genes encoding either ACTH receptor or melanocortin 2 receptor accessory protein are responsible for the disease in about 50% of cases, named FGD type 1 and type 2, respectively. Patients may present with hyperpigmentation, recurrent infections, failure to thrive, hypoglycemic seizures, and coma in infancy or early childhood. Here we report the case of a 17-day-old newborn diagnosed with FGD type 1 who presented with hyperbilirubinemia and hyperpigmentation, a sign which... Neonatology journals http://www.medworm.com/rss/comments.php?id=5092955 Wed, 22 Jun 2011 23:00:00 +0100 5092955 http://www.medworm.com/index.php?rid=5092954&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21701220%26dopt%3DAbstract We describe three positive influenza AH1N1 cases in a neonatal unit during the influenza pandemic in Spain. One term baby presented with an upper respiratory tract infection, another preterm infant with an apnea episode following nosocomial infection, and thirdly, a term infant of a mother with influenza AH1N1 had severe respiratory distress and pneumothoraces needing high-frequency ventilation. PMID: 21701220 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092954 Wed, 22 Jun 2011 23:00:00 +0100 5092954 http://www.medworm.com/index.php?rid=5092953&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21701221%26dopt%3DAbstract Conclusions: This short dexamethasone course appears effective in facilitating extubation. Randomised trials with long-term follow-up are needed to determine the role of extremely low-dose dexamethasone in preterm babies with evolving BPD. PMID: 21701221 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092953 Wed, 22 Jun 2011 23:00:00 +0100 5092953 http://www.medworm.com/index.php?rid=5092951&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21701222%26dopt%3DAbstract Conclusion: High-dose erythromycin is associated with greater weight gain in preterm infants <32 weeks gestational age, who are predominantly fed cow's milk-based protein formulas. PMID: 21701222 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092951 Wed, 22 Jun 2011 23:00:00 +0100 5092951 http://www.medworm.com/index.php?rid=5092947&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21701223%26dopt%3DAbstract Authors: Yadav K, Field D No abstract available. PMID: 21701223 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092947 Wed, 22 Jun 2011 23:00:00 +0100 5092947 http://www.medworm.com/index.php?rid=5092944&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21701224%26dopt%3DAbstract Authors: Ng PC No abstract available. PMID: 21701224 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092944 Wed, 22 Jun 2011 23:00:00 +0100 5092944 http://www.medworm.com/index.php?rid=5092964&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21701210%26dopt%3DAbstract Conclusions: Compared with PLV, infants ventilated using volume-targeted ventilation had reduced death/BPD, duration of ventilation, pneumothoraces, hypocarbia and periventricular leukomalacia/severe intraventricular hemorrhage. Further studies are needed to assess neurodevelopmental outcomes. PMID: 21701210 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092964 Tue, 21 Jun 2011 23:00:00 +0100 5092964 http://www.medworm.com/index.php?rid=5092963&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21701211%26dopt%3DAbstract Conclusion: In our study, all infants admitted to the NICU at a gestational age of 22 weeks were discharged from the hospital alive. This might suggest that infants after 22 weeks' gestation be considered eligible for active treatment in Japan, though considering the size of the material, generalizibility of the results cannot be considered guaranteed. PMID: 21701211 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092963 Tue, 21 Jun 2011 23:00:00 +0100 5092963 http://www.medworm.com/index.php?rid=5092962&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21701212%26dopt%3DAbstract Conclusion:These findings suggest that infants requiring surgical ligation for a hsPDA are at high risk for significant changes in cerebral oxygenation, whereas those receiving either indomethacin or conservative management maintain relatively stable cerebral oxygenation levels. Additional research is necessary to determine if NIRS monitoring identifies infants with a hsPDA at highest risk for brain injury. PMID: 21701212 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092962 Tue, 21 Jun 2011 23:00:00 +0100 5092962 http://www.medworm.com/index.php?rid=5092961&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21701213%26dopt%3DAbstract Conclusions: As compared with infants born after preterm labor to mothers without preeclampsia, infants born after early-onset preeclampsia presented with a stronger postnatal systemic inflammatory reaction. Antenatal exposure to preeclampsia may induce fetal leukocyte priming and regulation of inflammation, and thereby modify postnatal inflammatory reactions and morbidity. PMID: 21701213 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092961 Tue, 21 Jun 2011 23:00:00 +0100 5092961 http://www.medworm.com/index.php?rid=5092960&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21701214%26dopt%3DAbstract Conclusions: Lipid emulsions are an isotonic high-calorie source which can be given safely enterally instead of intravenously in the immediate neonatal period of very-low-birth-weight infants without clinical adverse effects and with almost complete absorption. There are potential advantages to oral administration of a lipid emulsion starting in early life which require further investigation. PMID: 21701214 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092960 Tue, 21 Jun 2011 23:00:00 +0100 5092960 http://www.medworm.com/index.php?rid=5092959&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21701215%26dopt%3DAbstract Conclusion: A tilting-down manoeuvre of the head of term and preterm neonates can cause an increase of HbO(2), Hb and HbT. tiltSvO(2) can be calculated out of these changes. By introducing two quality criteria, reproducibility of cerebral NIRS measurements (cTOI and tiltSvO(2)) improved. PMID: 21701215 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092959 Tue, 21 Jun 2011 23:00:00 +0100 5092959 http://www.medworm.com/index.php?rid=5092958&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21701216%26dopt%3DAbstract Conclusions: 3D scanning is an accurate and practical method to estimate BSA in newborns. Individual and repeated measurements from day to day are possible. Further studies are warranted in preterm and sick neonates. PMID: 21701216 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=5092958 Tue, 21 Jun 2011 23:00:00 +0100 5092958 http://www.medworm.com/index.php?rid=4949841&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21654182%26dopt%3DAbstract Authors: Saugstad OD No abstract available. PMID: 21654182 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4949841 Thu, 02 Jun 2011 23:00:00 +0100 4949841 http://www.medworm.com/index.php?rid=4694334&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21455007%26dopt%3DAbstract Conclusion: Regular glycerin suppositories did not reduce the time to full enteral feeds in infants born at <32 weeks' gestation in our setting. PMID: 21455007 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4694334 Thu, 31 Mar 2011 23:00:00 +0100 4694334 http://www.medworm.com/index.php?rid=4694333&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21455008%26dopt%3DAbstract Conclusions: The great majority of infants with CONS sepsis was successfully treated with cefazolin. The use of vancomycin could be restricted to specific cases. Despite the consistent use of cefazolin in neonatal CONS sepsis over an extended period of time, cefazolin MIC values remained low and in the susceptible range. Removal of the central venous catheter in infants with clinical symptoms of sepsis is an important therapeutic measure. PMID: 21455008 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4694333 Thu, 31 Mar 2011 23:00:00 +0100 4694333 http://www.medworm.com/index.php?rid=4694332&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21455009%26dopt%3DAbstract Conclusions:Gentamicin, as used and evaluated in this audit, showed no evidence of an increased risk of ototoxicity; what was observed was a statistically significant decrease in OAE failure rate. Vancomycin, by contrast, was associated with ototoxicity. PMID: 21455009 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4694332 Thu, 31 Mar 2011 23:00:00 +0100 4694332 http://www.medworm.com/index.php?rid=4694331&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21455010%26dopt%3DAbstract Authors: Haverkaemper S, Marquardt T, Hausser I, Timme K, Kuehn T, Hertzberg C, Rossi R This paper describes a neonate with type II Gaucher disease. The phenotype was unusually severe with congenital ichthyosis, hepatosplenomegaly, muscular hypotonia, myoclonus and respiratory failure. Electron microscopy of the skin revealed lamellar body contents in the stratum corneum interstices, appearances considered to be typical of type II Gaucher disease. The baby died from respiratory failure 1 month postpartum having made no neurological progress. Molecular analysis identified a previously not reported homozygous null mutation, c.1505G→A of the β-glucocerebrosidase gene. PMID: 21455010 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4694331 Thu, 31 Mar 2011 23:00:00 +0100 4694331 http://www.medworm.com/index.php?rid=4694330&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21455011%26dopt%3DAbstract Conclusions: Adult male OHM demonstrate programmed cardiac dysfunction. Given the growing number of pregnancies complicated by hyperglycemia, additional assessment of cardiac function of adults born to diabetic mothers may be warranted. PMID: 21455011 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4694330 Thu, 31 Mar 2011 23:00:00 +0100 4694330 http://www.medworm.com/index.php?rid=4694329&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21471705%26dopt%3DAbstract Conclusions: This statement provides the principles identified by French neonatologists on which to base their decisions concerning the ending of life. Arguments are set forth, discussed and compared with international statements and previously published considerations. PMID: 21471705 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4694329 Thu, 31 Mar 2011 23:00:00 +0100 4694329 http://www.medworm.com/index.php?rid=4636993&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21430391%26dopt%3DAbstract Conclusion: Both fat mass and cardiac septal thickness are increased in newborn infants of women with T1DM and GDM in spite of efforts to achieve good glycaemic control during pregnancy. PMID: 21430391 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4636993 Thu, 24 Mar 2011 00:00:00 +0100 4636993 http://www.medworm.com/index.php?rid=4636992&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21430392%26dopt%3DAbstract Conclusions: We conclude that the late-gestation fetal sheep responds to hypotensive stress with increases in LH mRNA but not LH secretion. LH, FSH and PRL changes are therefore unlikely to contribute to the fetal response to cerebral hypoperfusion. PMID: 21430392 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4636992 Thu, 24 Mar 2011 00:00:00 +0100 4636992 http://www.medworm.com/index.php?rid=4636991&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21430393%26dopt%3DAbstract Conclusions: The increase in the peripheral blood flow along with the decrease in the peripheral vascular resistance indices, without an increase in the systemic blood flow at 24 h of age, indicated vasodilation in skin and subcutaneous tissue during the transitional period in VLBW infants. FBF and LBF can be useful parameters as indicators of both peripheral and systemic circulation. PMID: 21430393 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4636991 Thu, 24 Mar 2011 00:00:00 +0100 4636991 http://www.medworm.com/index.php?rid=4636990&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21430394%26dopt%3DAbstract Authors: Fowlie PW, McGuire W No abstract available. PMID: 21430394 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4636990 Thu, 24 Mar 2011 00:00:00 +0100 4636990 http://www.medworm.com/index.php?rid=4575293&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21372593%26dopt%3DAbstract Conclusions: In VLBW neonates, up to 2.3 ml/kg of blood (corresponding to 2.4% of calculated circulating blood volume) can be drawn for scientific purposes without compromising basic hemodynamic parameters, Hgb and Ht values, blood component transfusions or fluid requirements. PMID: 21372593 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4575293 Wed, 02 Mar 2011 00:00:00 +0100 4575293 http://www.medworm.com/index.php?rid=4575292&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21372594%26dopt%3DAbstract Authors: Raghuveer TS, Bloom BT For more than 50 years it has been known that oxygen therapy can lead to retinopathy of prematurity (ROP). Recent clinical research has led many neonatologists to lower the target oxygen saturation alarm limits to 85-93% and to titrate the inspired oxygen in small increments. Despite efforts to optimize oxygen therapy, the number of cases of severe ROP remains high as more extremely low birth weight infants survive. Based on new insights into the pathogenesis of ROP, there are multiple interventions, in addition to optimizing oxygen therapy that may help decrease severe ROP. Interventions that have the potential to prevent phase I ROP (birth to ≤32 weeks PMA) include increasing retinal erythropoietin (exogenous rHuEPO) and serum IGF-1 (breast milk and/... Neonatology journals http://www.medworm.com/rss/comments.php?id=4575292 Wed, 02 Mar 2011 00:00:00 +0100 4575292 http://www.medworm.com/index.php?rid=4575291&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21372595%26dopt%3DAbstract Conclusions: In the ventilated preterm baboon lung, expression of sIL-6R and dynamic modulation of sgp130 expression appear to modulate the activity and inflammatory potential of IL-6. PMID: 21372595 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4575291 Wed, 02 Mar 2011 00:00:00 +0100 4575291 http://www.medworm.com/index.php?rid=4575290&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21372596%26dopt%3DAbstract Conclusions: MF63 has a dual action on DA, the constriction being associated with accessory dilatation. The latter effect should be explained before considering further a mPGES1 inhibitor for management of PDA. PMID: 21372596 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4575290 Wed, 02 Mar 2011 00:00:00 +0100 4575290 http://www.medworm.com/index.php?rid=4521334&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21311200%26dopt%3DAbstract Conclusion: 'Adequate' chest excursion is a subjective parameter for guidance of appropriate ventilation during neonatal resuscitation. PMID: 21311200 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4521334 Wed, 09 Feb 2011 00:00:00 +0100 4521334 http://www.medworm.com/index.php?rid=4521333&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21311201%26dopt%3DAbstract Conclusions: Our results support the notion that betamethasone could be a better choice than dexamethasone for antenatal lung maturation. PMID: 21311201 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4521333 Wed, 09 Feb 2011 00:00:00 +0100 4521333 http://www.medworm.com/index.php?rid=4461859&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21273792%26dopt%3DAbstract Conclusion: The T-piece provided consistent PIP during a single 10 s sustained inflation with less variation in pressure compared with the flow-inflating bag. Sustained inflations >3 s were difficult to achieve with a self-inflating bag. PMID: 21273792 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4461859 Wed, 26 Jan 2011 00:00:00 +0100 4461859 http://www.medworm.com/index.php?rid=4461858&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21273793%26dopt%3DAbstract Conclusion: Z-scores of TAPSE values were calculated and percentile charts were established to serve as reference data for ready application in preterm and term neonates with structurally normal hearts and with congenital heart disease in the future. PMID: 21273793 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4461858 Wed, 26 Jan 2011 00:00:00 +0100 4461858 http://www.medworm.com/index.php?rid=4461857&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21273794%26dopt%3DAbstract Conclusions: Our results suggest that the change in serum adiponectin levels may reflect postnatal growth from birth to term-equivalent age in preterm infants. PMID: 21273794 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4461857 Wed, 26 Jan 2011 00:00:00 +0100 4461857 http://www.medworm.com/index.php?rid=4395730&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21228602%26dopt%3DAbstract Conclusions: With the exception of surfactant timing, guidelines on surfactant replacement therapy seem to be implemented in daily clinical practice in European NICUs. PMID: 21228602 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4395730 Tue, 11 Jan 2011 00:00:00 +0100 4395730 http://www.medworm.com/index.php?rid=4395733&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21212696%26dopt%3DAbstract Conclusions: Our data provide evidence for a lack of adequate tetanus immunity in 14.2% of newborns delivered in an Austrian University Hospital. This investigation is emphasizing the importance of stringent regimens concerning prenatal vaccination care, even in countries with generalized immunization programs. If indicated, maternal immunization during pregnancy should be initiated for protection of newborns. PMID: 21212696 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4395733 Wed, 05 Jan 2011 00:00:00 +0100 4395733 http://www.medworm.com/index.php?rid=4395732&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21212697%26dopt%3DAbstract Conclusions: Risks of mortality and irreversible brain injury among healthy infants admitted for newborn jaundice are urgent reminders to promote education of communities, families and primary health care providers, especially in a fractured health system. Known risk factors for severe hyperbilirubinemia were overwhelmed by the effect of advanced ABE. PMID: 21212697 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4395732 Wed, 05 Jan 2011 00:00:00 +0100 4395732 http://www.medworm.com/index.php?rid=4395731&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21212698%26dopt%3DAbstract Conclusions: OFS is a novel objective indicator of infants' feeding ability that takes into account infants' skills and endurance. As a clinical tool, it can help caretakers monitor infants' skills as they transition to oral feeding and identify oral feeding issues arising from immature skills and/or poor endurance. PMID: 21212698 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4395731 Wed, 05 Jan 2011 00:00:00 +0100 4395731 http://www.medworm.com/index.php?rid=4395735&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21212694%26dopt%3DAbstract Conclusion: Group mean values indicate that antenatal exposure to MgSO(4) does not significantly affect intestinal blood flow velocity in newborn preterm infants. However, the significant negative relationship between mean blood flow velocity and time from birth to blood flow velocity measurement in exposed infants suggests that there may be measurable effects of MgSO(4) exposure within the hours immediately after birth. Trials that prospectively evaluate the development of intestinal blood flow velocities are needed to further clarify potential effects of antenatal MgSO(4) on the gastrointestinal tract of preterm infants. PMID: 21212694 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4395735 Tue, 04 Jan 2011 00:00:00 +0100 4395735 http://www.medworm.com/index.php?rid=4395734&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21212695%26dopt%3DAbstract Authors: Warrick C, Nicholl R PMID: 21212695 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4395734 Tue, 04 Jan 2011 00:00:00 +0100 4395734 http://www.medworm.com/index.php?rid=4322292&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21196777%26dopt%3DAbstract Conclusions: In Sri Lankans intron 2 CT repeat polymorphism of the IGF-1 gene appears to be a significant contributor to IGF-1 levels and birth size in primiparous pregnancies. PMID: 21196777 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4322292 Thu, 30 Dec 2010 00:00:00 +0100 4322292 http://www.medworm.com/index.php?rid=4322293&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21196776%26dopt%3DAbstract Conclusion: The result contributes to an emerging body of evidence that antenatal treatment with corticosteroids does not permanently affect lung structure or function. PMID: 21196776 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4322293 Wed, 22 Dec 2010 00:00:00 +0100 4322293 http://www.medworm.com/index.php?rid=4272375&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21150226%26dopt%3DAbstract Authors: Ma L, Liu C, Wang Y, Li S, Zhai S, Gu X, Liu F, Yan A, Guo W, Li Y, Xiao M, Yin J, Li Y, Liu X, Wang R, Kirpalani H, Sun B Dramatic progress has occurred in neonatal intensive care in tertiary centers in mid-eastern China. We investigated the characteristics of neonatal respiratory failure (NRF) including the incidence, management, outcomes and costs in 14 neonatal intensive care units (NICUs) of Hebei, a province at an intermediate economic level in China. Over a period of 12 consecutive months in 2007-2008, perinatal data were collected prospectively from all NICU admissions (n = 11,100). NRF was defined as severe hypoxemia requiring respiratory support for more than 24 h, and was diagnosed in 1,875 newborns (16.9%). The average birth weight of newborns with NRF was 2,200 g ... Neonatology journals http://www.medworm.com/rss/comments.php?id=4272375 Fri, 10 Dec 2010 00:00:00 +0100 4272375 http://www.medworm.com/index.php?rid=4272381&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21150224%26dopt%3DAbstract Conclusions: A low oxygen saturation approach reduces severe retinopathy of prematurity by 50%, i.e. from 20.9 to 9.5%, and bronchopulmonary dysplasia/lung problems by 25%, i.e. from 40.8 to 29.7%. Further randomized trials are needed to provide definite conclusions and to assess whether reducing oxygen saturation has an impact on mortality among very and extremely low birth weight infants. PMID: 21150224 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4272381 Thu, 09 Dec 2010 00:00:00 +0100 4272381 http://www.medworm.com/index.php?rid=4272378&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21150225%26dopt%3DAbstract Conclusion: This study describes 7 infants with SSSS and stresses the important role of skin substitutes as Omiderm® and Suprathel® as valuable adjuvant treatment modality. PMID: 21150225 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4272378 Thu, 09 Dec 2010 00:00:00 +0100 4272378 http://www.medworm.com/index.php?rid=4272374&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21150227%26dopt%3DAbstract Conclusions: Administration of LMWHs in neonates has to be performed carefully to avoid bleeding side effects due to their high anticoagulant efficacy in cord PPP and WB. PMID: 21150227 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4272374 Thu, 09 Dec 2010 00:00:00 +0100 4272374 http://www.medworm.com/index.php?rid=4248565&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21135563%26dopt%3DAbstract Conclusion: The premature intestine is highly responsive to initial bacterial colonization and the specific bacteria-related proteome changes may contribute to the stress response that makes the immature intestine sensitive to the pro-inflammatory effects of enteral feeding. PMID: 21135563 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4248565 Sat, 04 Dec 2010 00:00:00 +0100 4248565 http://www.medworm.com/index.php?rid=4248564&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21135564%26dopt%3DAbstract Conclusion: The figures of this report display reference ranges for NRBC according to gestational age and postnatal age. An NRBC count above the 95% limit at birth is associated with a higher risk of subsequently developing severe IVH and severe ROP. We speculate that this association is because an elevated NRBC count is a marker for prenatal hypoxia. PMID: 21135564 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4248564 Sat, 04 Dec 2010 00:00:00 +0100 4248564 http://www.medworm.com/index.php?rid=4248563&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21135565%26dopt%3DAbstract Conclusions: The proposed classification may be used to retrospectively categorize the etiology of preterm births, and the BEP algorithm facilitates this task enabling greater accuracy and precision in clinical data. PMID: 21135565 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4248563 Sat, 04 Dec 2010 00:00:00 +0100 4248563 http://www.medworm.com/index.php?rid=4248562&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21135566%26dopt%3DAbstract Conclusions: Magnesium sulfate and melatonin, two agents acting at different stages of HI brain damage, administered either alone or in combination, significantly reduced the percent infarcted brain volume and TUNEL positivity, suggesting that these agents may confer a possible benefit in the treatment of infants with HI encephalopathy. PMID: 21135566 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4248562 Sat, 04 Dec 2010 00:00:00 +0100 4248562 http://www.medworm.com/index.php?rid=4248561&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21135567%26dopt%3DAbstract Authors: Abdel-Halim RE No abstract available. PMID: 21135567 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4248561 Sat, 04 Dec 2010 00:00:00 +0100 4248561 http://www.medworm.com/index.php?rid=4248560&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21135568%26dopt%3DAbstract Authors: Obladen M PMID: 21135568 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4248560 Fri, 03 Dec 2010 00:00:00 +0100 4248560 http://www.medworm.com/index.php?rid=4215459&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21109756%26dopt%3DAbstract Conclusion: A low flow rate during neonatal mask ventilation may be a good alternative approach in reducing mask leak, provided that inflation time and flow rate warrants set pressures. Only large leaks seem to influence delivered pressures and volumes. Before resuscitation guidelines are advised, more studies on gas flow rates are needed. PMID: 21109756 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4215459 Thu, 25 Nov 2010 00:00:00 +0100 4215459 http://www.medworm.com/index.php?rid=4215458&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21109757%26dopt%3DAbstract Conclusions: It is possible that meconium aspiration delays normal decline of pulmonary vascular resistance shortly after birth through lung parenchymal injury. The subsequent increase of cGMP in MAS may be an adaptive response to prevent further elevation of pulmonary arterial pressure by inducing NO. PMID: 21109757 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4215458 Thu, 25 Nov 2010 00:00:00 +0100 4215458 http://www.medworm.com/index.php?rid=4199523&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21088433%26dopt%3DAbstract Conclusions: It is possible to reduce newborn mortality in all countries and regions. Most important to achieve these goals is, however, political will. PMID: 21088433 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4199523 Thu, 18 Nov 2010 00:00:00 +0100 4199523 http://www.medworm.com/index.php?rid=4199522&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21088434%26dopt%3DAbstract Conclusions: Equations proposed to predict survival in CDH patients may not discriminate survivors from nonsurvivors in the ECMO population. In this highest risk group, factors such as birth weight and Apgar score are less critical in estimating mortality risk than indicators of ventilation and oxygenation that reflect the degree of pulmonary hypoplasia. PMID: 21088434 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4199522 Thu, 18 Nov 2010 00:00:00 +0100 4199522 http://www.medworm.com/index.php?rid=4164817&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21071980%26dopt%3DAbstract Conclusions: Our results suggest that the expression of GATA-6 at the early stages of the preterm lung may be related to impaired postnatal alveolar development. PMID: 21071980 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4164817 Fri, 12 Nov 2010 00:00:00 +0100 4164817 http://www.medworm.com/index.php?rid=4164820&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21063127%26dopt%3DAbstract Conclusions: These results indicate that BDNF and RANTES may be important factors in the selective vulnerability of ROP development in preterm infants. PMID: 21063127 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4164820 Tue, 09 Nov 2010 00:00:00 +0100 4164820 http://www.medworm.com/index.php?rid=4164819&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21063128%26dopt%3DAbstract This study aims to examine whether HB-EGF, a proven intestinal cytoprotective molecule, exerts its protective effects through modulation of AP-1 transcription factor after intestinal I/R injury. Thirty rats were randomly divided into the following 5 groups: (1) normal control group; (2) ischemia group; (3) I/R group; (4) ischemia group with HB-EGF (400 μg/kg), and (5) I/R group with HG-EGF (400 μg/kg). c-Fos and c-Jun messenger RNAs and protein levels were determined by real-time quantitative polymerase chain reaction (PCR) and Western analyses, respectively. Statistical analysis was performed using ANOVA with Dunn's test. The messenger RNA levels of the c-Fos and c-Jun increased after intestinal ischemia or the intestinal reperfusion phase. HB-EGF pretreatment significantly decreased c-... Neonatology journals http://www.medworm.com/rss/comments.php?id=4164819 Tue, 09 Nov 2010 00:00:00 +0100 4164819 http://www.medworm.com/index.php?rid=4164818&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21063129%26dopt%3DAbstract We present a case of severe hemorrhage in a preterm neonate after LMWH treatment and summarize the scarce data reported in the literature. PMID: 21063129 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4164818 Tue, 09 Nov 2010 00:00:00 +0100 4164818 http://www.medworm.com/index.php?rid=4164822&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21051909%26dopt%3DAbstract Conclusions: The current nutritional management of preterm infants is likely to lead to an early and severe DHA deficit which may represent, at 1 month of age, about half of the fetal DHA accumulation. PMID: 21051909 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4164822 Fri, 05 Nov 2010 00:00:00 +0100 4164822 http://www.medworm.com/index.php?rid=4164821&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21051910%26dopt%3DAbstract Conclusions: Of the responders, approximately 50% administer inhaled corticosteroids to premature infants either as a prophylaxis or treatment for BPD. Lack of beneficial evidence was the main reason for not administering inhaled steroids in about half of the units which took this approach. Future trials should address this discrepancy by aiming to establish a clear benefit-risk ratio of inhaled corticosteroids. PMID: 21051910 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4164821 Fri, 05 Nov 2010 00:00:00 +0100 4164821 http://www.medworm.com/index.php?rid=4164824&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21051907%26dopt%3DAbstract Conclusions: Anatomic path-based calculations of umbilical catheters can accurately predict radiographic measured lengths. Prospective studies to validate this method against actual inserted length are required before promoting this approach. PMID: 21051907 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4164824 Thu, 04 Nov 2010 00:00:00 +0100 4164824 http://www.medworm.com/index.php?rid=4164823&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21051908%26dopt%3DAbstract Conclusion: We found significant hyperglycemia-induced gene expression alterations in neonatal rat pulmonary tissue which may interfere with lung growth and biological signaling pathways. PMID: 21051908 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4164823 Thu, 04 Nov 2010 00:00:00 +0100 4164823 http://www.medworm.com/index.php?rid=4136571&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21042035%26dopt%3DAbstract Conclusions: Despite improvements in neonatal care, the rates of BPD and early mortality in newborns with CDH are still considerable. Several important risk factors for a worse outcome are reported in this nonrandomized prospective observational study. PMID: 21042035 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4136571 Sat, 30 Oct 2010 00:00:00 +0100 4136571 http://www.medworm.com/index.php?rid=4122150&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20980771%26dopt%3DAbstract We present 2 cases of premature infants with short bowel who received early supplementation of enteral Microlipid® and fish oil. This approach allowed us to discontinue Intralipid shortly after initiating feedings. The infants tolerated Microlipid/fish oil well without adverse reactions, had appropriate weight gain and ostomy output. They underwent bowel reanastomosis 3 weeks after enteral feeding began, and were discharged on full oral feedings. In case 1, the infant did not develop parenteral nutrition-associated cholestasis; in case 2, cholestasis had developed before initiating feeds, but was not aggravated by enteral fat and was improving prior to discharge. PMID: 20980771 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4122150 Wed, 27 Oct 2010 00:00:00 +0100 4122150 http://www.medworm.com/index.php?rid=4122149&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20980772%26dopt%3DAbstract Authors: Reiss I, Schaible T, van den Hout L, Capolupo I, Allegaert K, van Heijst A, Gorett Silva M, Greenough A, Tibboel D Congenital diaphragmatic hernia (CDH) is associated with high mortality and morbidity. To date, there are no standardized protocols for the treatment of infants with this anomaly. However, protocols based on the literature and expert opinion might improve outcome. This paper is a consensus statement from the CDH EURO Consortium prepared with the aim of achieving standardized postnatal treatment in European countries. During a consensus meeting between high-volume centers with expertise in the treatment of CDH in Europe (CDH EURO Consortium), the most recent literature on CDH was discussed. Thereafter, 5 experts graded the studies according to the Scottish Intercol... Neonatology journals http://www.medworm.com/rss/comments.php?id=4122149 Wed, 27 Oct 2010 00:00:00 +0100 4122149 http://www.medworm.com/index.php?rid=4122148&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20980773%26dopt%3DAbstract Conclusions: The kinetics of fecal HBD2 in the neonatal period indicate that this inducible defensin can be detected at high level in the feces of full-term and preterm infants, independently of gestational age or mode of feeding. The potential role of fecal HBD2 in detecting NEC is suggested. PMID: 20980773 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4122148 Wed, 27 Oct 2010 00:00:00 +0100 4122148 http://www.medworm.com/index.php?rid=4025871&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20881439%26dopt%3DAbstract Conclusions: Measurement of the CA is an easily accessible and reliable tool that may assist in establishing the diagnosis of PDA. PMID: 20881439 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4025871 Tue, 28 Sep 2010 23:00:00 +0100 4025871 http://www.medworm.com/index.php?rid=4025877&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20881433%26dopt%3DAbstract Authors: Thomas W, Speer CP Chorioamnionitis as a major risk factor for spontaneous preterm birth, especially at earlier gestational ages, contributes to prematurity-associated mortality and morbidity. A gestation-independent effect of chorioamnionitis on neonatal outcome is much more difficult to assess. The influence of chorioamnionitis on neonatal outcome has become less evident with advances in neonatal care. A short-term beneficial effect of histological, but not clinical chorioamnionitis on incidence and severity of respiratory distress syndrome in preterm infants is evident. This maturational effect is accompanied by a susceptibility of the lung for further postnatal injury, which predisposes for bronchopulmonary dysplasia. Chorioamnionitis is associated with cystic periventricu... Neonatology journals http://www.medworm.com/rss/comments.php?id=4025877 Mon, 27 Sep 2010 23:00:00 +0100 4025877 http://www.medworm.com/index.php?rid=4025876&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20881434%26dopt%3DAbstract Authors: Mazzucchelli I, Garofoli F, Decembrino L, Castiglia D, Tadini G, Bellingeri A, Borghesi A, Tzialla C, Manzoni P, Stronati M The case of a male neonate of 41 weeks' gestation who developed blistering of the skin immediately after birth is described. His parents were consanguineous Tunisians. Electron microscopy of a cutaneous biopsy showed skin cleavage within the lamina lucida and immunoepitope mapping revealed a complete absence of laminin 332 expression. These findings referred to the diagnosis of junctional epidermolysis bullosa (JEB) Herlitz type. The neonate died at 3 months of age due to sepsis. Molecular analysis of laminin 332 chain genes LAMA3, LAMB3 and LAMC2 disclosed a novel homozygous nonsense mutation in LAMA3 (p.Y955X). Clinical and laboratory analyses are essen... Neonatology journals http://www.medworm.com/rss/comments.php?id=4025876 Fri, 24 Sep 2010 23:00:00 +0100 4025876 http://www.medworm.com/index.php?rid=4025875&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20881435%26dopt%3DAbstract Conclusions: TGF-β(2) attenuates IL-1β-induced pro-inflammatory cytokine production in immature human IECs by inhibiting ERK signalling. The anti-inflammatory effect of TGF-β(2) is dependent on SMAD6. Breast milk TGF-β(2) may provide the neonate with important immunoregulatory support. TGF-β(2) might provide a novel means to improve intestinal immunophysiology in premature neonates. PMID: 20881435 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4025875 Fri, 24 Sep 2010 23:00:00 +0100 4025875 http://www.medworm.com/index.php?rid=4025874&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20881436%26dopt%3DAbstract Conclusions: Our study suggests that hypoalbuminemia following abdominal surgery causes a higher serum UB at comparable serum TB in newborns. PMID: 20881436 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4025874 Fri, 24 Sep 2010 23:00:00 +0100 4025874 http://www.medworm.com/index.php?rid=4025873&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20881437%26dopt%3DAbstract Conclusion: IUGR is associated with a longer and thinner intestine at birth, and during the immediate postnatal period, intestinal adaptation and bacterial colonization are altered in IUGR piglets born at full term. PMID: 20881437 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4025873 Fri, 24 Sep 2010 23:00:00 +0100 4025873 http://www.medworm.com/index.php?rid=4025872&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20881438%26dopt%3DAbstract Conclusions: Levosimendan improves cerebral and systemic perfusion and oxygenation in critically ill infants suffering from LCOS. PMID: 20881438 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=4025872 Fri, 24 Sep 2010 23:00:00 +0100 4025872 http://www.medworm.com/index.php?rid=3962098&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20829634%26dopt%3DAbstract Conclusion: Although an additional 30 s to ensure effective ventilation does not impair the speed or success in achieving ROSC, delaying circulatory support for as long as 1.5 min of initial ventilation may be harmful. PMID: 20829634 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=3962098 Fri, 10 Sep 2010 23:00:00 +0100 3962098 http://www.medworm.com/index.php?rid=3962099&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20820107%26dopt%3DAbstract Authors: Halliday HL, Speer CP No abstract available. PMID: 20820107 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=3962099 Fri, 03 Sep 2010 23:00:00 +0100 3962099 http://www.medworm.com/index.php?rid=3912066&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20798552%26dopt%3DAbstract Conclusions: We conclude that p38 MAPK phosphorylation is crucially involved in LPS activation and could explain the differences in early cytokine response between neonatal and adult blood. PMID: 20798552 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=3912066 Thu, 26 Aug 2010 23:00:00 +0100 3912066 http://www.medworm.com/index.php?rid=3912065&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20798553%26dopt%3DAbstract Conclusion: Gestational age at birth and parameters reflecting postnatal adaptation were the most precise factors for assessment of the prognosis of VLBW infants after pPROM within the first hour of life. Apart from anhydramnios, obstetric factors did not predict neonatal outcome. At 1 h of age, our models of perinatal risk factors were more effective in predicting a favorable outcome than an adverse outcome. PMID: 20798553 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=3912065 Thu, 26 Aug 2010 23:00:00 +0100 3912065 http://www.medworm.com/index.php?rid=3912064&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20798554%26dopt%3DAbstract Authors: Obladen M By 1769, it was known to Morgagni that the ductus arteriosus may persist until adulthood. In 1835, Jörg linked delayed postnatal closure with disturbed respiration, a discovery that was afterwards forgotten for a century. When blood gas analysis became available, the association between persisting patency and diminished oxygenation resurfaced. When it became known that prostaglandins played a role in maintaining ductal patency, the development of pharmacologic intervention with cyclooxygenase inhibitors immediately followed. This rapid progress was due to the interaction between basic science, pediatric cardiology, and neonatology disciplines at the Cardiovascular Research Institute in San Francisco, coordinated by Julius Comroe, as well as President Kennedy's fou... Neonatology journals http://www.medworm.com/rss/comments.php?id=3912064 Thu, 26 Aug 2010 23:00:00 +0100 3912064 http://www.medworm.com/index.php?rid=3912063&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20798555%26dopt%3DAbstract Conclusions: Although scientific evidence suggests that IVSB is not effective in asphyxiated newborns and current guidelines do not recommend its use, 42.2% of the consulted neonatologists in Europe would use it, with significant differences between but not within countries. There were no differences regarding additional measures to overcome asphyxia. Strategies to implement use of internationally accepted guidelines are needed. PMID: 20798555 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=3912063 Thu, 26 Aug 2010 23:00:00 +0100 3912063 http://www.medworm.com/index.php?rid=3899953&cid=s_36786_69_f&fid=36786&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20733329%26dopt%3DAbstract Conclusion: FCD of the buccal mucosa decreases after the first week of life. PMID: 20733329 [PubMed - as supplied by publisher] (Source: Neonatology) Neonatology journals http://www.medworm.com/rss/comments.php?id=3899953 Mon, 23 Aug 2010 23:00:00 +0100 3899953