MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Neurocritical Care' source. Wed, 08 Feb 2012 20:43:28 +0100 http://www.medworm.com/index.php?rid=5668759&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F57279258t6131089%2F Conclusion  TCD pulsatility index can be easily and quickly assessed but is usually misinterpreted as a descriptor of CVR. The mathematical model presents a complex relationship between PI and multiple haemodynamic variables. Content Type Journal ArticleCategory Original ArticlesPages 1-9DOI 10.1007/s12028-012-9672-6Authors Nicolás de Riva, Division of Neurosurgery, Department of Clinical Neurosciences, Addenbrooke’s Hospital, University of Cambridge, Hills Road, Box 167, Cambridge, CB2 0QQ UKKarol P. Budohoski, Division of Neurosurgery, Department of Clinical Neurosciences, Addenbrooke’s Hospital, University of Cambridge, Hills Road, Box 167, Cambridge, CB2 0QQ UKPeter Smielewski, Division of Neurosurgery, Department of Clinical Neurosciences, Addenbrooke’s Ho... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5668759 Mon, 06 Feb 2012 19:36:07 +0100 5668759 http://www.medworm.com/index.php?rid=5668760&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv51145215177u2t4%2F Conclusions  Transferred patients had similar rates of death, disability and LOS as directly admitted patients, though worse 3-month cognitive outcomes. Prolonged time to interhospital transfer was associated with an increased risk of aneurysm rerupture and tracheostomy. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s12028-012-9679-zAuthors Ashley R. Catalano, Department of Neurosurgery, Mount Sinai School of Medicine, One Gustave Levy Place, Box 1136, New York, NY 10029, USAH. R. Winn, Department of Neurosurgery, Lennox Hill Hospital, 100 East 77th Street, New York, NY 10075, USAErrol Gordon, Neuroscience Intensive Care Unit, Departments of Neurosurgery and Neurology, Mount Sinai School of Medicine, New York, NY, USAJennifer A. Frontera, ... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5668760 Mon, 06 Feb 2012 19:36:06 +0100 5668760 http://www.medworm.com/index.php?rid=5660921&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F8553128683514h56%2F Conclusions  A severe increase of ICP leading to CPP below 30 mmHg and BtipO2 below 10 mmHg is associated with an increase of the L/P ratio, thus seems to be critical thresholds for cerebral ischemia under these conditions. Content Type Journal ArticleCategory Translational ResearchPages 1-8DOI 10.1007/s12028-012-9675-3Authors Karlis Purins, Department of Neuroscience, Section of Neurosurgery, Uppsala University, 751 85 Uppsala, SwedenPer Enblad, Department of Neuroscience, Section of Neurosurgery, Uppsala University, 751 85 Uppsala, SwedenLars Wiklund, Department of Surgical Sciences, Section of Anaesthesia and Intensive Care, Uppsala University, Uppsala, SwedenAnders Lewén, Department of Neuroscience, Section of Neurosurgery, Uppsala University, 751 85 Up... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5660921 Fri, 03 Feb 2012 07:21:15 +0100 5660921 http://www.medworm.com/index.php?rid=5660922&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg73477n5r52kg448%2F Content Type Journal ArticleCategory Response to Letter to the EditorPages 1-4DOI 10.1007/s12028-012-9674-4Authors Peter Le Roux, Department of Neurosurgery, University of Pennsylvania Medical Center, Philadelphia, PA, USAMichael Diringer, Neurology/Neurosurgery ICU, Washington University, St. Louis, MO, USA Journal Neurocritical CareOnline ISSN 1556-0961Print ISSN 1541-6933 (Source: Neurocritical Care) Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5660922 Tue, 31 Jan 2012 07:11:09 +0100 5660922 http://www.medworm.com/index.php?rid=5639531&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb500r0011vg815x2%2F Conclusions  In acute stroke patients, intubation prior to interventional recanalization therapy can delay treatment initiation. The implementation of an I-SOP accelerates interventional treatment initiation. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s12028-012-9671-7Authors Oliver Herrmann, Department of Neurology, University Hospital Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, GermanyAndreas Hug, Spinal Cord Injury Center, University Hospital Heidelberg, Schlierbacher Landstr. 200a, 69118 Heidelberg, GermanyJulian Bösel, Department of Neurology, University Hospital Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, GermanyJuliana Johanna Petersen, Institute of General Practice, Goethe-University of Frankfurt/Main, Theo... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5639531 Tue, 24 Jan 2012 07:55:42 +0100 5639531 http://www.medworm.com/index.php?rid=5621286&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe48x205r30px7643%2F Conclusions  Despite CPP targeted therapy with vasopressor medication, oral Nimodipine was associated with a decrease in MAP and CPP. When Nimodipine administration was associated with a decrease in MAP, there were concomitant drops in PbtO2 and CBF. These findings suggest that MAP support after oral Nimodipine may be important to maintain adequate CBF in patients with poor-grade subarachnoid hemorrhage. Content Type Journal ArticlePages 1-5DOI 10.1007/s12028-012-9670-8Authors H. Alex Choi, Division of Neurocritical Care, The Neurologic Institute of New York, Columbia University College of Physicians and Surgeons, Milstein Hospital Building 8 Center, 177 Fort Washington Ave, New York, NY 10032, USASang-Bae Ko, Division of Neurocritical Care, The Neurologic Institute ... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5621286 Fri, 20 Jan 2012 07:07:26 +0100 5621286 http://www.medworm.com/index.php?rid=5621287&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fhx102j1400641t76%2F Conclusions  Our experience and prior reports suggest that periodic eyelid opening following cardiac arrest is associated with a burst-suppression pattern on EEG. Since burst-suppression is highly (though not invariably) predictive of a poor outcome in this patient population, intensivists should be familiar with this neurological sign. Prospective studies are needed to define the neurophysiology of this phenomena and clarify its clinical significance. Content Type Journal ArticleCategory Practical PearlPages 1-4DOI 10.1007/s12028-011-9665-xAuthors Joseph M. Ferrara, Division of Neurology, Virginia Tech Carilion School of Medicine and Research Institute, 2 Riverside Cir, Roanoke, VA 24016, USADavid J. Houghton, Division of Movement Disorders, University of Louisvill... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5621287 Thu, 19 Jan 2012 07:00:34 +0100 5621287 http://www.medworm.com/index.php?rid=5611193&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy722k58845284708%2F Conclusions  This case demonstrates that even excessive doses of ITB can let the patients survive without sequelae if treated promptly and offensively. A pertinent problem during detoxification is the question of when to restart ITB to avoid drug withdrawal. Content Type Journal ArticleCategory Practical PearlPages 1-5DOI 10.1007/s12028-011-9669-6Authors Benjamin Berger, Department of Neurology, University Hospital Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, GermanyBarbara Vienenkoetter, Department of Neurosurgery, University Hospital Heidelberg, 69120 Heidelberg, GermanyMirjam Korporal, Department of Neurology, University Hospital Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, GermanyAndrea Rocco, Department of Neurology, University Hospital Heidel... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5611193 Sat, 14 Jan 2012 06:55:15 +0100 5611193 http://www.medworm.com/index.php?rid=5599506&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu84767x532u84367%2F Conclusion  Larger series and phase I clinical trial(s) of ketamine for treatment of refractory SE seem warranted. Content Type Journal ArticleCategory Practical PearlPages 1-7DOI 10.1007/s12028-011-9668-7Authors Andreas H. Kramer, Department of Critical Care Medicine, University of Calgary, ICU Administration, Ground Floor, McCaig Tower, 3134 Hospital Dr NW, Calgary, AB T2N 2T9, Canada Journal Neurocritical CareOnline ISSN 1556-0961Print ISSN 1541-6933 (Source: Neurocritical Care) Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5599506 Thu, 12 Jan 2012 06:42:49 +0100 5599506 http://www.medworm.com/index.php?rid=5584711&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F7vm32q0l5115610p%2F Conclusion  It is imperative to recognize such cases where hypertension causes edema within the posterior fossa resulting in secondary hydrocephalus. Focusing management on lowering blood pressure avoids unnecessary or prolonged CSF diversion. Content Type Journal ArticleCategory Practical PearlPages 1-7DOI 10.1007/s12028-011-9663-zAuthors Abhay Kumar, Department of Neurology, Washington University School of Medicine, 660 S. Euclid Ave, Campus Box 8111, St. Louis, MO 63110, USASalah G. Keyrouz, Department of Neurology, University of Arkansas for Medical Sciences, Little Rock, AR, USAJon T. Willie, Neurological Surgery, Washington University School of Medicine, St. Louis, MO, USARajat Dhar, Department of Neurology, Washington University School of Medicine, 660 S. Eucli... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5584711 Wed, 11 Jan 2012 06:56:58 +0100 5584711 http://www.medworm.com/index.php?rid=5584712&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F283538k647m422u5%2F Conclusions  Immunomodulating therapy should be considered in the management of select patients with spinal vasculitis which may lead to improved clinical outcome and potentially disease resolution. Content Type Journal ArticleCategory Practical PearlPages 1-5DOI 10.1007/s12028-011-9667-8Authors Jeffrey T. Jacob, Department of Neurologic Surgery, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USAShota Tanaka, Department of Neurologic Surgery, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USAChristopher P. Wood, Department of Radiology, Mayo Clinic College of Medicine, Rochester, MN, USAEelco F. Wijdicks, Department of Neurology, Mayo Clinic College of Medicine, Rochester, MN, USAGiuseppe Lanzino, Department of N... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5584712 Tue, 10 Jan 2012 06:41:25 +0100 5584712 http://www.medworm.com/index.php?rid=5573085&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu68l672386x67772%2F Conclusions  No difference in neurological outcome at discharge was detected in predominantly non-shockable IHCA patients treated with MTH. This finding, if confirmed with further study, may define a population of patients for whom this costly and resource intensive therapy should be withheld. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s12028-011-9664-yAuthors Pierre Kory, Division of Pulmonary, Critical Care and Sleep Medicine, Beth Israel Medical Center, New York, NY, USAMayuko Fukunaga, Division of Pulmonary, Critical Care and Sleep Medicine, Beth Israel Medical Center, New York, NY, USAJoseph P. Mathew, Division of Pulmonary, Critical Care and Sleep Medicine, Beth Israel Medical Center, New York, NY, USABimaljeet Singh, Division of ... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5573085 Fri, 06 Jan 2012 16:44:31 +0100 5573085 http://www.medworm.com/index.php?rid=5573086&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr2w45521074g8586%2F Conclusion  Acute pupil-sparing partial oculomotor nerve palsy should be recognized as a neurological complication of cardiac surgery. Pupillary involvement can be helpful in identifying the underlying etiology. Content Type Journal ArticleCategory NeuroimagePages 1-4DOI 10.1007/s12028-011-9666-9Authors Shamir Haji, Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USAManoj K. Mittal, Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USAEelco F. Wijdicks, Department of Neurology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA Journal Neurocritical CareOnline ISSN 1556-0961Print ISSN 1541-6933 (Source: Neurocritical Care) Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5573086 Thu, 05 Jan 2012 06:52:25 +0100 5573086 http://www.medworm.com/index.php?rid=5553335&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F8x64932006x4542r%2F Conclusions  This preliminary data suggests that LCM may be a safe and effective alternative for treatment of seizures in critically ill patients. Further prospective, randomized controlled trials are needed to confirm these findings and further explore the incidence of adverse effects. Content Type Journal ArticleCategory Original ArticlePages 1-5DOI 10.1007/s12028-011-9662-0Authors Sunil Cherry, Department of Neurology, Emory University School of Medicine, 1365 Clifton Road, NE Clinic A, Atlanta, GA 30322, USALilith Judd, Department of Neurology, Emory University School of Medicine, 1365 Clifton Road, NE Clinic A, Atlanta, GA 30322, USAJuan Carlos Muniz, Department of Neurology, Emory University School of Medicine, 1365 Clifton Road, NE Clinic A, Atlanta, GA 30322,... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5553335 Wed, 28 Dec 2011 06:53:50 +0100 5553335 http://www.medworm.com/index.php?rid=5545646&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fqn7351362r844747%2F Abstract  Cerebral venous sinus thrombosis (CVST) often occurs in young patients and is treated with acute and then long-term oral anticoagulation. It is important to decide when to discontinue anticoagulation, as lifelong anticoagulation exposes the patient to considerable cumulative risk. However, a lack of high quality studies makes choosing a duration of anticoagulation after CVST difficult. In this article, we review the evidence for different treatment durations in several common clinical scenarios of CVST. In addition, when no direct evidence is available, we discuss and extrapolate from the more comprehensively studied situation of systemic venous thromboembolic disease. Recommendations are graded using standard criteria for the level of evidence. Conten... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5545646 Thu, 22 Dec 2011 06:44:42 +0100 5545646 http://www.medworm.com/index.php?rid=5539363&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm6trr68377266510%2F Content Type Journal ArticleCategory EditorialPages 1-3DOI 10.1007/s12028-011-9660-2Authors Eelco F. M. Wijdicks, Mayo Clinic, Rochester, MN, USA Journal Neurocritical CareOnline ISSN 1556-0961Print ISSN 1541-6933 (Source: Neurocritical Care) Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5539363 Tue, 20 Dec 2011 06:42:35 +0100 5539363 http://www.medworm.com/index.php?rid=5516362&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F695j5u7576352546%2F Conclusions  OH is an uncommon manifestation of dorsal medullary lesions and can rarely show significant worsening in severity following surgical resection of the lesion. Medical management in conjunction with physical rehabilitation may potentially result in recovery. Content Type Journal ArticleCategory Practical PearlPages 1-5DOI 10.1007/s12028-011-9656-yAuthors Sara Hocker, Division of Critical Care Neurology, Mayo Clinic, Mayo W8-B, 200 First Street SW, Rochester, MN 55905, USAJason M. Hoover, Department of Neurological Surgery, Mayo Clinic, Rochester, MN, USARoss C. Puffer, Mayo Medical School, Rochester, MN, USAFredric B. Meyer, Department of Neurological Surgery, Mayo Clinic, Rochester, MN, USA Journal Neurocritical CareOnline ISSN 1556-0961Print ISSN ... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5516362 Wed, 14 Dec 2011 06:57:03 +0100 5516362 http://www.medworm.com/index.php?rid=5516364&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg42n4132812hww2w%2F Conclusions  In this cohort of tPA-treated patients, post-stroke seizures were associated with atrial fibrillation and early mortality. Content Type Journal ArticleCategory Original ArticlePages 1-5DOI 10.1007/s12028-011-9657-xAuthors P. Couillard, Department of Clinical Neurosciences, University of Calgary, Foothills Medical Centre, 1403 29th Street NW, Calgary, AB T2N 2T9, CanadaM. A. Almekhlafi, Department of Clinical Neurosciences, University of Calgary, Foothills Medical Centre, 1403 29th Street NW, Calgary, AB T2N 2T9, CanadaA. Irvine, Department of Clinical Neurosciences, University of Calgary, Foothills Medical Centre, 1403 29th Street NW, Calgary, AB T2N 2T9, CanadaN. Jetté, Department of Clinical Neurosciences, University of Calgary, Foothills Medical Centre, ... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5516364 Tue, 13 Dec 2011 06:55:55 +0100 5516364 http://www.medworm.com/index.php?rid=5516363&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq32112255n5h67w8%2F Conclusions  IVN appears relatively safe and effective in treating VSP by TCD, but there was no difference in clinical outcomes between nicardipine and control patients at 30 and 90 days. In the future, larger studies are needed to evaluate the clinical outcome with IVN. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s12028-011-9659-8Authors Na Lu, Clinical Research Internship Study Program (CRISP), Mayo Clinic, Jacksonville, FL, USADaniel Jackson, Department of Pharmacy, Mayo Clinic, Jacksonville, FL, USASothear Luke, Department of Neurology, Mayo Clinic, 4500 San Pablo Rd, Jacksonville, FL 32224, USAEmir Festic, Department of Critical Care, Mayo Clinic, 4500 San Pablo Rd, Jacksonville, FL 32224, USARicardo A. Hanel, Department of Neu... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5516363 Tue, 13 Dec 2011 06:55:55 +0100 5516363 http://www.medworm.com/index.php?rid=5478054&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc7626515x7645736%2F Conclusion  LIS can reveal BAVS. Its diagnosis relies on clinical examination. In this case, rapid neuro-interventional treatment permitted reversal of symptoms. This could not have been possible under sedation. Content Type Journal ArticleCategory Practical PearlPages 1-3DOI 10.1007/s12028-011-9655-zAuthors G. Lacroix, Department of Anesthesiology and Intensive Care, Sainte Anne Teaching Military Hospital, Toulon, FranceD. Couret, Department of Anesthesiology and Intensive Care, Aix-Marseille University, 13284 Marseille, FranceX. Combaz, Department of Neuroradiology, Aix-Marseille University, 13284 Marseille, FranceB. Prunet, Department of Anesthesiology and Intensive Care, Sainte Anne Teaching Military Hospital, Toulon, FranceN. Girard, Department of Neuroradiology,... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5478054 Thu, 01 Dec 2011 06:58:55 +0100 5478054 http://www.medworm.com/index.php?rid=5450342&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F33442v5758465525%2F Conclusions  cEEG has applications in monitoring cerebral dysfunction in addition to detecting seizure activity in the intensive care unit. It may serve a vital role in multi-modality monitoring for early recognition of neurological complications from brain injuries that may not be noticed clinically, which is paramount to early intervention. Content Type Journal ArticleCategory Practical PearlPages 1-5DOI 10.1007/s12028-011-9650-4Authors C. R. Newey, Department of Adult Neurology, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195-5245, USAA. Sarwal, Neurologic Institute, Cleveland Clinic, Cerebrovascular Disease Center, 9500 Euclid Avenue, Cleveland, OH 44195-5245, USAS. Hantus, Neurologic Institute, Cleveland Clinic, Cerebrovascular Disease Center, 9500 Euc... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5450342 Wed, 23 Nov 2011 16:38:56 +0100 5450342 http://www.medworm.com/index.php?rid=5450343&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj2315j5106370428%2F Content Type Journal ArticleCategory Letter to the EditorPages 1-3DOI 10.1007/s12028-011-9654-0Authors Paul E. Marik, Department of Medicine, Eastern Virginia Medical School, 825 Fairfax Ave, Suite 410, Norfolk, VA 23507, USA Journal Neurocritical CareOnline ISSN 1556-0961Print ISSN 1541-6933 (Source: Neurocritical Care) Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5450343 Wed, 23 Nov 2011 16:38:55 +0100 5450343 http://www.medworm.com/index.php?rid=5450344&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F28000264725p5317%2F Conclusions  Cerebral vasospasm causes shortening of τ. Shorter τ at the side of aneurysm can be observed before formal TCD signs of vasospasm are observed, therefore, potentially reducing time to escalation of treatment. Content Type Journal ArticleCategory Original ArticlePages 1-6DOI 10.1007/s12028-011-9653-1Authors Magdalena Kasprowicz, Academic Neurosurgery Unit, Addenbrooke’s Hospital, Cambridge, CB20QQ Box167, UKMarek Czosnyka, Academic Neurosurgery Unit, Addenbrooke’s Hospital, Cambridge, CB20QQ Box167, UKMartin Soehle, Department of Anesthesiology and Intensive Care Medicine, University of Bonn, Bonn, GermanyPeter Smielewski, Academic Neurosurgery Unit, Addenbrooke’s Hospital, Cambridge, CB20QQ Box167, UKPeter J. Kirkpatrick, Academic Neurosurgery Uni... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5450344 Wed, 23 Nov 2011 16:38:54 +0100 5450344 http://www.medworm.com/index.php?rid=5432879&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa800vu648n197848%2F Conclusion  In patients receiving neurocritical care for cerebral edema, the adjunct of a potassium sparing diuretic (canrenone) to mannitol therapy reduces potassium urinary loss, prevents hypokalemia, and reduces the incidence of new cardiac arrhythmias. Content Type Journal ArticleCategory Original ArticlePages 1-6DOI 10.1007/s12028-011-9652-2Authors Federico Bilotta, Department of Anesthesiology, Critical Care and Pain Medicine, “Sapienza” University Rome, Italy, Viale Acherusio 16, 00199 Rome, ItalyFederico Giovannini, Department of Anesthesiology, Critical Care and Pain Medicine, “Sapienza” University Rome, Italy, Viale Acherusio 16, 00199 Rome, ItalyFlavia Aghilone, Department of Anesthesiology, Critical Care and Pain Medicine, “Sapienza” University... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5432879 Sat, 19 Nov 2011 06:50:45 +0100 5432879 http://www.medworm.com/index.php?rid=5432881&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb553471348l55115%2F Conclusions  LPS administration before SAH worsens DDAV through a myeloid cell-dependent mechanism supporting studies in humans which show that systemic inflammation increases the likelihood of developing DDAV. Content Type Journal ArticleCategory Translational ResearchPages 1-8DOI 10.1007/s12028-011-9651-3Authors Saksith Smithason, Cerebrovascular Center, Cleveland Clinic, NC30, 9500 Euclid Ave., Cleveland, OH 44195, USAShari Korday Moore, Neuroinflammation Research Center, Cleveland Clinic, NC30, 9500 Euclid Ave., Cleveland, OH 44195, USAJ. Javier Provencio, Cerebrovascular Center, Cleveland Clinic, NC30, 9500 Euclid Ave., Cleveland, OH 44195, USA Journal Neurocritical CareOnline ISSN 1556-0961Print ISSN 1541-6933 (Source: Neurocritical Care) Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5432881 Thu, 17 Nov 2011 06:58:29 +0100 5432881 http://www.medworm.com/index.php?rid=5432880&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fkv5211q447hj8376%2F Abstract  The use of hyperosmolar agents for intracranial hypertension was introduced in the early 20th century and remains a mainstay of therapy for patients with cerebral edema. Both animal and human studies have demonstrated the efficacy of two hyperosmolar agents, mannitol and hypertonic saline, in reducing intracranial pressure via volume redistribution, plasma expansion, rheologic modifications, and anti-inflammatory effects. However, because of physician and institutional variation in therapeutic practices, lack of standardized protocols for initiation and administration of therapy, patient heterogeneity, and a paucity of randomized controlled trials have yielded little Class I evidence on which clinical decisions can be based, most current evidence regarding the use... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5432880 Thu, 17 Nov 2011 06:58:29 +0100 5432880 http://www.medworm.com/index.php?rid=5390017&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fyj7338w8t83l2826%2F Abstract  The use of antibiotic-coated external ventricular catheters has been controversial among practitioners; although several papers have documented decreased adherence of microbes to catheters treated with antibiotics, there is no universally accepted practice standard for the use of coated catheters for the prevention of clinical infection. In this paper, we review the in vivo and in vitro evidence for antibiotic-coated catheters. Content Type Journal ArticleCategory ReviewPages 1-9DOI 10.1007/s12028-011-9647-zAuthors Maya A. Babu, Department of Neurologic Surgery, The Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USARobin Patel, Department of Infectious Diseases, The Mayo Clinic, Rochester, MN 55905, USAW. Richard Marsh, Department of Neurologic Surgery... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5390017 Wed, 02 Nov 2011 05:49:30 +0100 5390017 http://www.medworm.com/index.php?rid=5390020&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F10x585253554q457%2F Conclusions  Using NCUs registered with the NCS, current geographic access to NCUs is limited in the US, and geographic disparities in access to care exist. While additional NCUs may exist beyond those identified by the NCS database, we identify geographies with limited access to NCUs and offer a population-based planning perspective on the further development of the US neurocritical care system. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s12028-011-9644-2Authors Michael J. Ward, Department of Emergency Medicine, University of Cincinnati, 231 Albert Sabin Way, Room 1654H ML 0769, Cincinnati, OH 45267-0769, USALori A. Shutter, Departments of Neurosurgery & Neurology, UC Neuroscience Institute, University of Cincinnati, Cincinnati, OH, U... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5390020 Tue, 01 Nov 2011 16:51:02 +0100 5390020 http://www.medworm.com/index.php?rid=5390019&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F95371015675hm5w3%2F Conclusions  Sudden clinical deterioration after SAH with coma and a fixed “blown” pupil may result from hemorrhage extension into the brainstem parenchyma rather than oculomotor nerve injury from compression or stretch. Content Type Journal ArticleCategory NeuroimagePages 1-2DOI 10.1007/s12028-011-9648-yAuthors Jennifer E. Fugate, Division of Critical Care Neurology, Mayo Clinic, Rochester, MN 55905, USAGrant W. Mallory, Department of Neurosurgery, Mayo Clinic, Rochester, MN 55905, USAEelco F. M. Wijdicks, Division of Critical Care Neurology, Mayo Clinic, Rochester, MN 55905, USA Journal Neurocritical CareOnline ISSN 1556-0961Print ISSN 1541-6933 (Source: Neurocritical Care) Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5390019 Tue, 01 Nov 2011 16:51:02 +0100 5390019 http://www.medworm.com/index.php?rid=5390018&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr5151x12845677mt%2F Conclusions  aSAH occur in a diurnal, morning prevalent pattern regardless of traditional aSAH risk factors. The association of these risk factors with existing onset patterns should be investigated in future studies. Content Type Journal ArticleCategory Original ArticlePages 1-5DOI 10.1007/s12028-011-9640-6Authors Richard E. Temes, Divison of Cerebrovascular Disease and Neurocritical Care, Rush University Medical Center, 1725 W. Harrison Street Suite 1121, Chicago, IL 60612, USAThomas Bleck, Divison of Cerebrovascular Disease and Neurocritical Care, Rush University Medical Center, 1725 W. Harrison Street Suite 1121, Chicago, IL 60612, USASiddharth Dugar, Divison of Cerebrovascular Disease and Neurocritical Care, Rush University Medical Center, 1725 W. Harrison Str... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5390018 Tue, 01 Nov 2011 16:51:02 +0100 5390018 http://www.medworm.com/index.php?rid=5390021&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F88r1h765nrt60552%2F Conclusions  Cerebral vein thrombosis is a potential complication of uterine fibroids with erythrocytosis. Content Type Journal ArticleCategory Practical PearlPages 1-3DOI 10.1007/s12028-011-9646-0Authors Jonathan Graff-Radford, Department of Neurology, Mayo Clinic, 200 1st Street SW, Rochester, MN 55905, USADavid T. Jones, Department of Neurology, Mayo Clinic, 200 1st Street SW, Rochester, MN 55905, USARajiv K. Pruthi, Department of Hematology, Mayo Clinic, Rochester, MN, USAKelly D. Flemming, Department of Neurology, Mayo Clinic, 200 1st Street SW, Rochester, MN 55905, USA Journal Neurocritical CareOnline ISSN 1556-0961Print ISSN 1541-6933 (Source: Neurocritical Care) Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5390021 Tue, 01 Nov 2011 16:51:00 +0100 5390021 http://www.medworm.com/index.php?rid=5365488&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fxhv223847321k403%2F Content Type Journal ArticleCategory EditorialPages 1-2DOI 10.1007/s12028-011-9645-1Authors Neeraj Badjatia, Neurological Institute of New York, Columbia University College of Physicians and Surgeons, MHB Suite 8-300, 177 Fort Washington Avenue, New York, NY 10032, USA Journal Neurocritical CareOnline ISSN 1556-0961Print ISSN 1541-6933 (Source: Neurocritical Care) Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5365488 Fri, 28 Oct 2011 16:58:59 +0100 5365488 http://www.medworm.com/index.php?rid=5365489&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn85w6434251n6514%2F Abstract  Delirium is the most common mental disturbance in critically-ill patients and results in significant morbidity and mortality. Haloperidol is a preferred agent for the treatment of delirium in this population because of its rapid onset of action and lack of hemodynamic effects. Despite its widespread use in the critical care setting, most of the relevant data are obtained from case series or extrapolated from non-critically-ill populations. This review provides an overview of haloperidol pharmacokinetics and a comprehensive summary of the evidence for various haloperidol dosing regimens in the treatment of delirium in critically-ill patients. A comprehensive literature search was conducted in Medline, Embase, and International Pharmaceutical Abstracts with “halop... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5365489 Fri, 28 Oct 2011 16:58:58 +0100 5365489 http://www.medworm.com/index.php?rid=5338234&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F45g62n5711019884%2F Conclusion  Administration of high-dose ambroxol should be considered as an alternative and effective approach to reduce the postoperative respiratory complications and improve the oxygenation status in acute CSCI patients. Content Type Journal ArticleCategory Original ArticlePages 1-6DOI 10.1007/s12028-011-9642-4Authors Qiang Li, Department of Intensive Care Unit, Peking University Third Hospital, 49 North Garden Rd, Haidian District, Beijing, 100191 People’s Republic of ChinaGaiqi Yao, Department of Intensive Care Unit, Peking University Third Hospital, 49 North Garden Rd, Haidian District, Beijing, 100191 People’s Republic of ChinaXi Zhu, Department of Intensive Care Unit, Peking University Third Hospital, 49 North Garden Rd, Haidian District, Beijing, 100191 P... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5338234 Tue, 18 Oct 2011 06:00:52 +0100 5338234 http://www.medworm.com/index.php?rid=5325400&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm142k76106715jp4%2F Conclusion  Early ECF NO x concentrations are of prognostic value after TBI. ECF NO x may be a useful biomarker for treatment trials targeted at nitric oxide metabolism. Content Type Journal ArticleCategory Original ArticlePages 1-4DOI 10.1007/s12028-011-9633-5Authors Martin M. Tisdall, Departments of Neuroanaesthesia and Neurocritical Care, The National Hospital for Neurology and Neurosurgery, Queen Square, London, WC1N 3BG UKKonrad Rejdak, Department of Neurology, Medical University of Lublin, Lublin, PolandNeil D. Kitchen, Victor Horsley Department of Neurosurgery, The National Hospital for Neurology and Neurosurgery, Queen Square, London, WC1N 3BG UKMartin Smith, Departments of Neuroanaesthesia and Neurocritical Care, The National Hospital for Neurology and Neu... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5325400 Sat, 15 Oct 2011 05:48:08 +0100 5325400 http://www.medworm.com/index.php?rid=5325401&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fcv43l6771w470553%2F Conclusions  Careful consideration should be exercised when emergently intubating acute ischemic stroke patients for endovascular treatment, because the rate of death and disability appears to be high. This increased rate is not explained by higher rates of subsequent aspiration pneumonia. Content Type Journal ArticleCategory Original ArticlePages 1-5DOI 10.1007/s12028-011-9638-0Authors Ameer E. Hassan, Zeenat Qureshi Stroke Research Center, Department of Neurology, University of Minnesota, 12-100 PWB, 516 Delaware St. SE, Minneapolis, 55455 USASaqib A. Chaudhry, Zeenat Qureshi Stroke Research Center, Department of Neurology, University of Minnesota, 12-100 PWB, 516 Delaware St. SE, Minneapolis, 55455 USAHaralabos Zacharatos, Zeenat Qureshi Stroke Research Center, De... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5325401 Thu, 13 Oct 2011 05:44:38 +0100 5325401 http://www.medworm.com/index.php?rid=5316911&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft76q585130h54611%2F Conclusions  Although, the hypothesis behind this study had promise, we were unable to reach our predefined goal. The possible causes for this shortcoming included the rarity of patients with brain death, the common practice in the Netherlands of obtaining consent for organ donation before brain death testing and the uneasiness of the staff in the presence of the patients’ relatives during brain death determination. Although, we cannot draw a conclusion from statistical evidence, we would recommend that relatives be given the opportunity to be present during brain death testing and, specifically, during the apnea test. Content Type Journal ArticleCategory Ethical MattersPages 1-8DOI 10.1007/s12028-011-9636-2Authors Erwin J. O. Kompanje, Department of Intensive Ca... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5316911 Wed, 12 Oct 2011 05:46:19 +0100 5316911 http://www.medworm.com/index.php?rid=5316913&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr6875r7m41725314%2F Conclusion  Cerebral infarction is a common and severe complication in adults with community-acquired bacterial meningitis. Preventing cerebral infarctions will be important in reducing the high morbidity and mortality rate in adults with community-acquired bacterial meningitis. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s12028-011-9634-4Authors Ewout S. Schut, Department of Neurology, Center of Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, University of Amsterdam, P.O. Box 22660, 1100 Amsterdam, The NetherlandsMarjolein J. Lucas, Department of Neurology, Center of Infection and Immunity Amsterdam (CINIMA), Academic Medical Center, University of Amsterdam, P.O. Box 22660, 1100 Amsterdam, The NetherlandsMatthijs C. ... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5316913 Wed, 12 Oct 2011 05:46:16 +0100 5316913 http://www.medworm.com/index.php?rid=5316912&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa51tg6u2r0706130%2F Conclusions  COG1410 administered at a dose of 2 mg/kg within 2 h after injury improves functional recovery in a murine model of ICH. Content Type Journal ArticleCategory Translational ResearchPages 1-11DOI 10.1007/s12028-011-9641-5Authors Daniel T. Laskowitz, Departments of Medicine (Neurology), Neurobiology, and Anesthesiology, Multidisciplinary Neuroprotection Laboratories, Duke University, Durham, NC, USABeilei Lei, Department of Anesthesiology, Multidisciplinary Neuroprotection Laboratories, Duke University, Durham, NC, USAHana N. Dawson, Department of Medicine (Neurology), Multidisciplinary Neuroprotection Laboratories, Duke University, Durham, NC, USAHaichen Wang, Department of Medicine (Neurology), Multidisciplinary Neuroprotection Laboratories, Duke Un... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5316912 Wed, 12 Oct 2011 05:46:16 +0100 5316912 http://www.medworm.com/index.php?rid=5316914&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg26761063330p7p9%2F Conclusions  Myeloid sarcoma can mimic subdural hematoma both clinically and radiologically. It should be considered when a patient with a prior leukemia and no antecedent trauma presents with an extra-axial lesion. Content Type Journal ArticleCategory Practical PearlPages 1-3DOI 10.1007/s12028-011-9631-7Authors G. M. Mallory, Department of Neurosurgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USAJ. J. Van Gompel, Department of Neurosurgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USAA. A. Rabinstein, Department of Neurology, Mayo Clinic, Rochester, MN 55905, USAJ. E. Fugate, Department of Neurology, Mayo Clinic, Rochester, MN 55905, USAG. Lanzino, Department of Neurosurgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA ... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5316914 Wed, 12 Oct 2011 05:46:15 +0100 5316914 http://www.medworm.com/index.php?rid=5306054&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq39500347h35348x%2F Conclusion  Lowering temperature rapidly reduced p38 activation and the subsequent p38-regulated production of pro-inflammatory cytokines and NO in ATP-activated microglia, suggesting that attenuation of early phase inflammatory responses via suppression of p38 in microglia is one possible neuroprotective mechanism of therapeutic hypothermia. Temperature elevation increased TNF-α and NO production in these cells. These temperature-dependent changes imply that monitoring of TNF-α and NO in the cerebrospinal fluid during the early phase might be useful as biomarkers for responses to therapeutic hypothermia and hyperthermia. Content Type Journal ArticleCategory Translational ResearchPages 1-8DOI 10.1007/s12028-011-9639-zAuthors Tomohiro Matsui, Department of Laborato... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5306054 Fri, 07 Oct 2011 05:47:09 +0100 5306054 http://www.medworm.com/index.php?rid=5306056&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2710gx66k532t885%2F Conclusions  Hematoma extension to the third and fourth ventricle seems to cause profound autonomic dysregulation, possibly contributing to poor outcome. Patients with IVH in this location should be monitored vigorously to prevent and treat complications of autonomic failure. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s12028-011-9637-1Authors Marek Sykora, Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, GermanyThorsten Steiner, Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, GermanySven Poli, Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, GermanyAndrea Rocco, Department of Neurology, University of He... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5306056 Thu, 06 Oct 2011 05:48:05 +0100 5306056 http://www.medworm.com/index.php?rid=5306055&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa4742w78122241l8%2F Conclusion  Neurological deterioration within 24 h of ICH onset is a powerful determinant of persistent neurological impairment. Careful reduction of the SBP by 1–10% in the first 24 h may lower the risk. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s12028-011-9632-6Authors Michael C. Christensen, Regulatory Affairs, Novo Nordisk A/S, Vandtårnsvej 114, 2860 Søborg, DenmarkStephen Morris, UCL Research Department of Epidemiology and Public Health, UCL, London, UKLaura Vallejo-Torres, UCL Research Department of Epidemiology and Public Health, UCL, London, UKCatherine Vincent, Merck Serono, Geneva, SwitzerlandStephan A. Mayer, Departments of Neurology and Neurological Surgery, Columbia University, New York, NY, USA Journal... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5306055 Thu, 06 Oct 2011 05:48:05 +0100 5306055 http://www.medworm.com/index.php?rid=5287519&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff40j289jk5t63m11%2F Conclusion  The prognostic role of PRx is confirmed but with a lower threshold of 0.05 for favorable outcome than for survival (0.25). Results for ICP are in line with current guidelines. However, the lower value in elderly and in females suggests increased vulnerability to intracranial hypertension in these groups. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s12028-011-9630-8Authors E. Sorrentino, Neurosurgery, University of Cambridge, Cambridge, UKJ. Diedler, Neurology, University of Heidelberg, Heidelberg, GermanyM. Kasprowicz, Institute of Biomedical Engineering and Instrumentation, Wroclaw University of Technology, Wroclaw, PolandK. P. Budohoski, Neurosurgery, University of Cambridge, Cambridge, UKC. Haubrich, Neurology, University ... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5287519 Sat, 01 Oct 2011 05:45:51 +0100 5287519 http://www.medworm.com/index.php?rid=5287520&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx60p758q526653j3%2F Conclusions  PRES is a rare complication of hemodynamic augmentation that should be considered in the differential diagnosis of delayed neurological decline in patients with aneurysmal SAH-associated cerebral vasospasm. The markedly asymmetric distribution of PRES lesions with sparing of the territory affected by vasospasm supports the hypothesis that hyperperfusion underlies the pathophysiology of this disorder. Content Type Journal ArticleCategory Practical PearlPages 1-5DOI 10.1007/s12028-011-9635-3Authors Barbara Voetsch, Department of Neurology, Lahey Clinic Medical Center, Tufts University School of Medicine, Burlington, MA, USANicholas Tarlov, Department of Neurology, Boston Medical Center, Boston University School of Medicine, 72 East Concord Street, C-3, Bo... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5287520 Sat, 01 Oct 2011 05:45:50 +0100 5287520 http://www.medworm.com/index.php?rid=5252133&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn5g6667721221876%2F Conclusion  Two-thirds of CT scans obtained in the PICU were portable because of patients’ intensity of therapy and illness severity. Portable CT showed major new pathology in greater than 1/3 and led to a change in management in 1/4 of higher acuity patients scanned. The estimated radiation dose from portable CT is within the current national guidelines. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s12028-011-9627-3Authors Kerri L. LaRovere, Department of Neurology, Children’s Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USAMolly S. Brett, Division of Critical Care Medicine, Department of Anesthesiology Perioperative and Pain Medicine, Children’s Hospital Boston and Harvard Medical School, 300 Longwood Avenue, Boston, MA... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5252133 Wed, 21 Sep 2011 05:49:22 +0100 5252133 http://www.medworm.com/index.php?rid=5228155&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg558370n463304g6%2F Conclusion  Broad level of support exists among the survey respondents (mostly neurologists and intensivists) for the establishment of neurological critical care units. Since neurology remains the predominant career path from which to draw neurointensivists, there may be a role for more comprehensive neurointensive care training within neurology residencies or an alternative training track for interested residents. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s12028-011-9628-2Authors Manjunath Markandaya, Divison of Neurosciences Critical Care, Department(s) of Neurology, Neurosurgery and Anesthesia/Critical Care Medicine, The Johns Hopkins University School of Medicine, Baltimore, MarylandKatherine P. Thomas, Divison of Neurosciences C... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5228155 Fri, 16 Sep 2011 05:47:31 +0100 5228155 http://www.medworm.com/index.php?rid=5228156&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F7574651708h707k3%2F Conclusion  We found no effect of EDLOS on neurologic outcome or resource utilization for patients presenting with spontaneous ICH. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s12028-011-9629-1Authors Jonathan Elmer, Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USADaniel J. Pallin, Department of Emergency Medicine, Brigham and Women’s Hospital, 75 Francis Street, Boston, MA, USAShan Liu, Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USACatherine Pearson, Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USAYuchiao Chang, Department of Medicine, Massachusetts General Hospital, Boston, MA, USACarlos A. Camargo, Department of Emergency Medicine, Massa... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5228156 Mon, 12 Sep 2011 15:53:42 +0100 5228156 http://www.medworm.com/index.php?rid=5211287&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff743u8184j2p2877%2F Content Type Journal ArticlePages 1-283DOI 10.1007/s12028-011-9625-5 Journal Neurocritical CareOnline ISSN 1556-0961Print ISSN 1541-6933 (Source: Neurocritical Care) Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5211287 Thu, 08 Sep 2011 06:01:49 +0100 5211287 http://www.medworm.com/index.php?rid=5192963&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fjx02k34581u42512%2F Conclusion  Our study suggests that the administration of PHT, LEV, and PGB in brain tumor patients with RSE is safe and highly effective. Content Type Journal ArticleCategory Original ArticlePages 1-5DOI 10.1007/s12028-011-9626-4Authors Christa B. Swisher, Division of Neurology, Department of Medicine, Duke University Medical Center (DUMC), Box 2900, Durham, NC 27710, USAMeghana Doreswamy, Division of Neurology, Department of Medicine, Duke University Medical Center (DUMC), Box 2900, Durham, NC 27710, USAKrista J. Gingrich, Division of Neurology, Department of Medicine, Duke University Medical Center (DUMC), Box 2900, Durham, NC 27710, USAJames J. Vredenburgh, Division of Neurology, Department of Medicine, Duke University Medical Center (DUMC), Box 2900, Durham, NC 2771... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5192963 Thu, 01 Sep 2011 06:14:59 +0100 5192963 http://www.medworm.com/index.php?rid=5185629&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa660780312561j33%2F Conclusions  Involuntary craniofacial lingual movements in the setting of flaccid quadriplegia following sepsis-associated encephalopathy are consistent with focal craniofacial brainstem myoclonus and constitutes a new syndrome. Botulinum toxin type A treatment maybe helpful in treatment. Content Type Journal ArticleCategory Practical PearlPages 1-6DOI 10.1007/s12028-011-9624-6Authors A. M. Cartagena, Department of Clinical Neurological Sciences, Schulich School of Medicine, The University of Western Ontario, 339 Windermere Rd, Rm B7-005, London, ON N6A 5A5, CanadaM. Jog, Department of Clinical Neurological Sciences, Schulich School of Medicine, The University of Western Ontario, 339 Windermere Rd, Rm B7-005, London, ON N6A 5A5, CanadaG. B. Young, Department of Clini... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5185629 Wed, 31 Aug 2011 05:52:32 +0100 5185629 http://www.medworm.com/index.php?rid=5164456&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F208n917603111386%2F Abstract  Neurocritical illness heavily burdens the developing world. In spite of a lack of resources for population-based health in most developing countries, there is an increasing demand for resource-intense strategies for acute neurological care. Factors including rising individual incomes in emerging economies, need for neurointensive care in humanitarian emergencies, growth of private hospitals, the rising burden of noncommunicable disease, and the practice of neurocritical care by specialists outside of neurology are discussed. Possible steps to improve the global practice of neurocritical care include: (1) emphasis on prevention of neurocritical illness through traffic safety and adequate outpatient treatment; (2) standardization of training requirements and skill s... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5164456 Wed, 24 Aug 2011 07:20:04 +0100 5164456 http://www.medworm.com/index.php?rid=5147838&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff6h26n152184ww33%2F Abstract  Although metabolic abnormalities have been linked with poor outcome after subarachnoid hemorrhage, there are limited data addressing the impact of glycemic control or benefits of glucose management after aneurysmal subarachnoid hemorrhage. A systematic literature search was conducted of English-language articles describing original research on glycemic control in patients with subarachnoid hemorrhage. Case reports and case series were excluded. A total of 22 publications were selected for this review. Among the 17 studies investigating glucose as an outcome predictor, glucose levels during hospitalization were more likely to predict outcome than admission glucose. In general, hyperglycemia was linked to worse outcome. While insulin therapy in subarachnoid hemorrha... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5147838 Thu, 18 Aug 2011 05:51:11 +0100 5147838 http://www.medworm.com/index.php?rid=5147839&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw440722345447806%2F Conclusion  Presence of an NI was associated with improved clinical outcomes. This effect was more evident in patients with SAH. Patients with ICH tend to have poor outcomes regardless of the presence of a NCCU or a NI. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s12028-011-9620-xAuthors Lisa Knopf, The University of Connecticut School of Medicine, Farmington, CT, USAIlene Staff, Hartford Hospital Research Department, Hartford, CT, USAJoao Gomes, The Cleveland Clinic, Cleveland, OH, USALouise McCullough, The University of Connecticut School of Medicine, Farmington, CT, USA Journal Neurocritical CareOnline ISSN 1556-0961Print ISSN 1541-6933 (Source: Neurocritical Care) Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5147839 Wed, 17 Aug 2011 05:42:41 +0100 5147839 http://www.medworm.com/index.php?rid=5147840&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj7763h1755818174%2F In this study, available medical literature was reviewed to examine whether brain tissue oxygen (PbtO2)-based therapy is associated with improved patient outcome after severe TBI. Clinical studies published between 1993 and 2010 that compared PbtO2-based therapy combined with intracranial and cerebral perfusion pressure (ICP/CPP)-based therapy to ICP/CPP-based therapy alone were identified from electronic databases, Index Medicus, bibliographies of pertinent articles, and expert consultation. For analysis, each selected paper had to have adequate data to determine odds ratios (ORs) and confidence intervals (CIs) of outcome described by the Glasgow outcome score (GOS). Seven studies that compared ICP/CPP and PbtO2- to ICP/CPP-based therapy were identified. There were no randomized studi... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5147840 Tue, 16 Aug 2011 06:09:54 +0100 5147840 http://www.medworm.com/index.php?rid=5147841&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr4668665041l1516%2F Conclusion  The FOUR score is an accurate predictor of outcome in TBI patients. It has some advantages over GCS, such as all components of FOUR score but not GCS can be rated in intubated patients. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s12028-011-9617-5Authors Farid Sadaka, St. John’s Mercy Medical Center, St Louis University, 621 S. New Ballas Rd, suite 4006B, St. Louis, MO 63141, USADarshan Patel, St. John’s Mercy Medical Center, St Louis University, 621 S. New Ballas Rd, suite 4006B, St. Louis, MO 63141, USARekha Lakshmanan, St. John’s Mercy Medical Center, St Louis University, 621 S. New Ballas Rd, suite 4006B, St. Louis, MO 63141, USA Journal Neurocritical CareOnline ISSN 1556-0961Print ISSN 1541-6933 (Source: Neur... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5147841 Tue, 16 Aug 2011 06:09:52 +0100 5147841 http://www.medworm.com/index.php?rid=5133726&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F281v626mpg313kx6%2F Conclusions  In patients at high risk for hemorrhage growth and poor outcome, early platelet transfusion improved platelet activity assay results and was associated with smaller final hemorrhage size and more independence at 3 months. Content Type Journal ArticlePages 1-6DOI 10.1007/s12028-011-9619-3Authors Andrew M. Naidech, Department of Neurology, Northwestern University’s Feinberg School of Medicine, 710 N Lake Shore Drive 11th Floor, Chicago, IL 60611, USAStorm M. Liebling, Department of Neurology, Northwestern University’s Feinberg School of Medicine, 710 N Lake Shore Drive 11th Floor, Chicago, IL 60611, USANeil F. Rosenberg, Department of Neurology, Northwestern University’s Feinberg School of Medicine, 710 N Lake Shore Drive 11th Floor, Chicago, IL ... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5133726 Fri, 12 Aug 2011 06:18:31 +0100 5133726 http://www.medworm.com/index.php?rid=5133727&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F12286rm674k1q233%2F Conclusions  Overall, neuroendocrine changes in ICH patients are not as profound as reported for ischemic stroke or subarachnoid hemorrhage. The clinical significance of increased LH and FSH levels in small ICH is unclear, whereas elevation of prolactin in large ICH was anticipated. Future randomized controlled trials should also focus on neuroendocrine parameters to clarify the impact of possible hormonal alterations on functional outcome. Content Type Journal ArticlePages 1-6DOI 10.1007/s12028-011-9622-8Authors Hagen B. Huttner, Department of Neurology, University of Erlangen, Schwabachanlage 6, 91054 Erlangen, GermanyInes-Christine Kiphuth, Department of Neurology, University of Erlangen, Schwabachanlage 6, 91054 Erlangen, GermanyLinda Teuber, Department of Neuro... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5133727 Fri, 12 Aug 2011 06:18:30 +0100 5133727 http://www.medworm.com/index.php?rid=5121159&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq195t72707426h55%2F Abstract  Statins were shown to have neuroprotective effects, with reduced vasospasm and delayed ischemic deficits in statin-treated patients after aneurysmal subarachnoid hemorrhage in two small, randomized, controlled clinical trials published in 2005. This review consolidated data from available published studies evaluating statin treatment for subarachnoid hemorrhage. A literature search was conducted to identify original research studies published through October 2010 testing immediate treatment with a statin in statin-naïve patients following aneurysmal SAH. Six randomized controlled clinical trials and four observational studies were identified. Despite inconsistent results among studies, a meta-analysis of randomized controlled data showed a significant reduction i... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5121159 Tue, 09 Aug 2011 05:44:49 +0100 5121159 http://www.medworm.com/index.php?rid=5111490&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp231m4p43014jk20%2F Conclusion  The diagnosis of CSWS should be strongly considered in hyponatremic pediatric patients with significant natriuresis following brain tumor resection, and a treatment initiated promptly to prevent neurologic sequeleae. Content Type Journal ArticlePages 1-6DOI 10.1007/s12028-011-9618-4Authors Douglas A. Hardesty, Department of Neurosurgery, Children’s Hospital of Philadelphia and University of Pennsylvania Medical Center, Wood Center, 6th Floor, 34th and Civic Center Boulevard, Philadelphia, PA 19104-4399, USATodd J. Kilbaugh, Department of Anesthesiology and Critical Care Medicine, Children’s Hospital of Philadelphia and University of Pennsylvania School of Medicine, Philadelphia, PA, USAPhillip B. Storm, Department of Neurosurgery, Children’s Hospital... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5111490 Sat, 06 Aug 2011 05:55:25 +0100 5111490 http://www.medworm.com/index.php?rid=5111489&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F825503pq96416671%2F We present the video of a patient who presented massive and ongoing rhythmic abdominal myoclonus in postanoxic coma. Content Type Journal ArticlePages 1-3DOI 10.1007/s12028-011-9616-6Authors Stephane Legriel, Intensive Care Unit, CH Versailles–Site André Mignot Hospital, 177 rue de Versailles, 78150 Le Chesnay, FranceMarie-Benedicte Le Stang, Intensive Care Unit, CH Versailles–Site André Mignot Hospital, 177 rue de Versailles, 78150 Le Chesnay, FranceSybille Merceron, Intensive Care Unit, CH Versailles–Site André Mignot Hospital, 177 rue de Versailles, 78150 Le Chesnay, FrancePierrick Cronier, Intensive Care Unit, CH Versailles–Site André Mignot Hospital, 177 rue de Versailles, 78150 Le Chesnay, FranceGilles Troche, Intensive Care Unit, CH Versailles–Site André Mignot H... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5111489 Sat, 06 Aug 2011 05:55:25 +0100 5111489 http://www.medworm.com/index.php?rid=5099143&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F6875m2k205534558%2F Abstract  Disruption of the hypothalamic–pituitary–adrenal axes may occur after aneurysmal subarachnoid hemorrhage, resulting in hypopituitarism. An electronic literature search was conducted to identify articles with English-language abstracts published between 1980 and March 2011, which addressed hypothalamic–pituitary–adrenal axis insufficiency and hormone replacement. A total of 18 observational and prospective, randomized studies were selected for this review. Limited data are available, evaluating pituitary effects during the acute stage after subarachnoid hemorrhage, with inconsistent results being reported. Overall, after acute subarachnoid hemorrhage, cortisol levels may initially be supranormal, decreasing toward normal levels over time. During the months t... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5099143 Tue, 02 Aug 2011 05:52:26 +0100 5099143 http://www.medworm.com/index.php?rid=5089729&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft605n8116n12807x%2F Conclusions  We demonstrated significant correlation between the known cerebral autoregulation index Mx and PAx. This new index of cerebrovascular pressure reactivity using ICP pulse wave information showed to have a strong association with outcome in TBI patients. Content Type Journal ArticlePages 1-8DOI 10.1007/s12028-011-9553-4Authors D. K. Radolovich, Neurosurgical Unit, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UKM. J. H. Aries, Neurosurgical Unit, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UKG. Castellani, Neurosurgical Unit, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UKA. Corona, Department of Intensive Care, Azienda Ospedaliera L Sacco, Milan, ItalyA. Lavinio, Neurosc... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5089729 Sat, 30 Jul 2011 05:56:22 +0100 5089729 http://www.medworm.com/index.php?rid=5089730&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm1078101g8865u6w%2F Abstract  Disruption of the hypothalamic–pituitary–adrenal axis may occur after aneurysmal subarachnoid hemorrhage, resulting in hypopituitarism. An electronic literature search was conducted to identify articles with English-language abstracts published between 1980 and March 2011 that addressed hypothalamic–pituitary–adrenal axis insufficiency and hormone replacement. A total of 18 observational and prospective, randomized studies were selected for this review. Limited data are available evaluating pituitary effects during the acute stage after subarachnoid hemorrhage, with inconsistent results reported. Overall, acutely after subarachnoid hemorrhage, cortisol levels may initially be supranormal, decreasing toward normal levels over time. During the months to year... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5089730 Fri, 29 Jul 2011 05:53:23 +0100 5089730 http://www.medworm.com/index.php?rid=5089731&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg2j67071v157pu70%2F Abstract  The daily practice of neurointensivists focuses on the recognition of subtle changes in the neurological examination, interactions between the brain and systemic derangements, and brain physiology. Common alterations such as fever, hyperglycemia, and hypotension have different consequences in patients with brain insults compared with patients of general medical illness. Various technologies have become available or are currently being developed. The session on “research and technology” of the first neurocritical care research conference held in Houston in September of 2009 was devoted to the discussion of the current status, and the research role of state-of-the art technologies in neurocritical patients including multi-modality neuromonitoring, biomarkers, ne... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5089731 Thu, 28 Jul 2011 05:47:53 +0100 5089731 http://www.medworm.com/index.php?rid=5089732&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp740x4x220715400%2F Abstract  Neurocritical care is a subspecialty of critical care medicine, dedicated to the care and the advancement of care of critically ill patients with neurosurgical or neurological diseases. Neurocritical care patients are heterogeneous, in both their disease process and the therapies they receive, however, several studies demonstrate that care of these patients in dedicated NeuroIntensive Care Units (neuroICUs) by neurointensivists, who coordinate their care is associated with reduced mortality and resource utilization. NeuroICUs foster innovation, and yet despite all the recent advances, much research needs to be undertaken in neurocritical care to better understand the disease pathophysiology and to demonstrate improved outcome with the use of goal-directed therapy ... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5089732 Thu, 28 Jul 2011 05:47:51 +0100 5089732 http://www.medworm.com/index.php?rid=5081465&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe177q73375727751%2F Abstract  This summary of the last session of the First Neurocritical Care Research Conference reviews the discussions about research priorities in neurocritical care. The first presentation reviewed current projects funded by the National Institute of Neurological Disorders and Stroke at the National Institutes of Health and potential models to follow including an independent Neurocritical Care Network or the creation of such a network with the goal of collaborating with already existing ones. Experienced neurointensivists then presented their views on the most common and important research questions that need to be answered and investigated in the field. Finally, utility of clinical registries was discussed emphasizing their importance as hypothesis generators. During the... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5081465 Wed, 27 Jul 2011 05:49:33 +0100 5081465 http://www.medworm.com/index.php?rid=5081464&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fnk2001846170j657%2F Abstract  Clinical trials provide a robust mechanism to advance science and change clinical practice across the widest possible spectrum. Fundamental in the Neurocritical Care Society’s mission is to promote Quality Patient Care by identifying and implementing best medical practices for acute neurological disorders that are consistent with the current scientific knowledge. The next logical step will be to foster rapid growth of our scientific body of evidence, to establish and disseminate these best practices. In this manuscript, five invited experts were impaneled to address questions, identified by the conference organizing committee as fundamental issues for the design of clinical trials in the neurological intensive care unit setting. Content Type Journal ArticleP... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5081464 Wed, 27 Jul 2011 05:49:33 +0100 5081464 http://www.medworm.com/index.php?rid=5081467&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd126772231734671%2F Abstract  Neurocritical care diseases carry a high morbidity and mortality. Therapeutic and technological advances in neurocritical care have greatly improved the outcome of a variety of life-threatening disorders including traumatic brain injury, acute ischemic stroke, intracerebral and subarachnoid hemorrhage, and anoxic injury following cardiac arrest. These advances have stemmed from a better understanding of the physiology of neurocritical care illnesses, improved neuromonitoring techniques, and the introduction of more efficacious treatments. Despite all the advances in neuromonitoring, diagnostic imaging, and emerging treatments, much research needs to be undertaken in neurocritical care. Many of the clinical trials carried out in the general critical care population... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5081467 Wed, 27 Jul 2011 05:49:30 +0100 5081467 http://www.medworm.com/index.php?rid=5081466&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm52704851r836544%2F Abstract  Outcome from trauma, surgery, and a variety of other medical conditions has been shown to be positively affected by providing treatment at facilities experiencing a high volume of patients with those conditions. An electronic literature search was made to identify English-language articles available through March 2011, addressing the effect of patient treatment volume on outcome for patients with subarachnoid hemorrhage. Limited data were identified, with 16 citations included in the current review. Over 60% of hospitals fall into the lowest case-volume quartile. Outcome is influenced by patient volume, with better outcome occurring in high-volume centers treating >60 cases per year. Patients treated at low-volume hospitals are less likely to experience definit... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5081466 Wed, 27 Jul 2011 05:49:30 +0100 5081466 http://www.medworm.com/index.php?rid=5064945&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk513392613n15251%2F Content Type Journal ArticlePages 1-2DOI 10.1007/s12028-011-9614-8Authors Jose I. Suarez, Department of Neurology, Baylor College of Medicine, 6501 Fannin Street, NB:320 Houston, TX, USAPeter D. LeRoux, Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA, USA Journal Neurocritical CareOnline ISSN 1556-0961Print ISSN 1541-6933 (Source: Neurocritical Care) Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5064945 Sat, 23 Jul 2011 05:52:51 +0100 5064945 http://www.medworm.com/index.php?rid=5064944&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F4137737x63x63410%2F Abstract  The science of nursing has long been discussed as a blending of the art and science of caring, and nursing research builds the evidence of support for nursing practice. Nurses and nursing care are key to successful neurocritical care research endeavors. Ideally nursing care should be evidence based and supported by solid research. The goal of nursing research is to expand the knowledge of caring for patients. Within the scope of nursing research, the priorities for research in neurocritical care should support this goal. In this manuscript, we discuss what we believe are the priorities of neurocritical care nursing research, the obstacles, and some possible solutions. Content Type Journal ArticlePages 1-8DOI 10.1007/s12028-011-9613-9Authors D. M. Olson, Depa... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5064944 Sat, 23 Jul 2011 05:52:51 +0100 5064944 http://www.medworm.com/index.php?rid=5064946&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj60234357gr71r44%2F Conclusions  These results indicate a complex relationship between tracheostomy timing and outcome, but suggest that a strategy of early tracheostomy, particularly when performed on patients with a reasonable chance of survival, results in a better overall clinical outcome than when the tracheostomy is performed in a delayed manner. Content Type Journal ArticlePages 1-9DOI 10.1007/s12028-011-9615-7Authors Elias B. Rizk, Department of Neurosurgery-EC110, Penn State MS Hershey Medical Center, Penn State College of Medicine, PO Box 859, Hershey, PA, USAAkshal S. Patel, Department of Neurosurgery-EC110, Penn State MS Hershey Medical Center, Penn State College of Medicine, PO Box 859, Hershey, PA, USAChristina M. Stetter, Department of Public Health Sciences, Penn State M... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5064946 Sat, 23 Jul 2011 05:52:46 +0100 5064946 http://www.medworm.com/index.php?rid=5064947&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F25762u66nwl1150h%2F Abstract  Hemodynamic augmentation therapy is considered standard treatment to help prevent and treat vasospasm and delayed cerebral ischemia. Standard triple-H therapy combines volume expansion (hypervolemia), blood pressure augmentation (hypertension), and hemodilution. An electronic literature search was conducted of English-language papers published between 2000 and October 2010 that focused on hemodynamic augmentation therapies in patients with subarachnoid hemorrhage. Among the eligible reports identified, 11 addressed volume expansion, 10 blood pressure management, 4 inotropic therapy, and 12 hemodynamic augmentation in patients with unsecured aneurysms. While hypovolemia should be avoided, hypervolemia did not appear to confer additional benefits over normovolemic t... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5064947 Sat, 23 Jul 2011 05:52:45 +0100 5064947 http://www.medworm.com/index.php?rid=5064948&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu028t28013214524%2F Abstract  Subarachnoid hemorrhage (SAH) is an acute cerebrovascular event which can have devastating effects on the central nervous system as well as a profound impact on several other organs. SAH patients are routinely admitted to an intensive care unit and are cared for by a multidisciplinary team. A lack of high quality data has led to numerous approaches to management and limited guidance on choosing among them. Existing guidelines emphasize risk factors, prevention, natural history, and prevention of rebleeding, but provide limited discussion of the complex critical care issues involved in the care of SAH patients. The Neurocritical Care Society organized an international, multidisciplinary consensus conference on the critical care management of SAH to address this nee... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5064948 Wed, 20 Jul 2011 12:28:48 +0100 5064948 http://www.medworm.com/index.php?rid=5064949&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fvv77x7n355183881%2F Conclusions  SAH survivors have increased long-term mortality and stroke rates compared with a matched non-SAH population. SAH-induced cardiac injury is associated with an increased risk of death and heart failure hospitalization. Content Type Journal ArticlePages 1-8DOI 10.1007/s12028-011-9592-xAuthors Jonathan G. Zaroff, Kaiser Northern California Division of Research, San Francisco, CA, USAJonathan Leong, Kaiser San Francisco Medical Center, 2350 Geary Boulevard, Room 206, San Francisco, CA 94115, USAHelen Kim, University of California San Francisco Center for Cerebrovascular Research, San Francisco, CA, USAWilliam L. Young, University of California San Francisco Center for Cerebrovascular Research, San Francisco, CA, USASean P. Cullen, Kaiser Redwood City Medical ... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5064949 Tue, 19 Jul 2011 05:50:12 +0100 5064949 http://www.medworm.com/index.php?rid=5064950&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F44560660v71m22t0%2F Conclusions  Bedside ONSD measurement, performed by neurointensivists, is an accurate, non-invasive method to identify ICP > 20 mmHg in a heterogeneous group of patients with acute brain injury. ONSD ≥0.48 cm has the greatest accuracy, however, internal validation of ONSD criteria may be required. Content Type Journal ArticlePages 1-10DOI 10.1007/s12028-011-9606-8Authors Venkatakrishna Rajajee, Department of Neurosurgery, University of Michigan Health System, 3552 Taubman Health Care Center, 1500 E. Medical Center Dr, SPC 5338, Ann Arbor, MI 48109-5338, USAMonique Vanaman, Department of Neurosurgery, University of Michigan Health System, 3552 Taubman Health Care Center, 1500 E. Medical Center Dr, SPC 5338, Ann Arbor, MI 48109-5338, USAJeffrey... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5064950 Tue, 19 Jul 2011 05:50:11 +0100 5064950 http://www.medworm.com/index.php?rid=5064951&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fkt66x5p1n08x7303%2F Conclusion  Prior to this report, there have only been 2 documented cases of concomitant intracranial and visceral artery aneurysms. These reports serve to remind the clinician that intracranial aneurysms may be only part of a systemic pathology, which should be taken into account when unexpected complications arise postoperatively. Content Type Journal ArticlePages 1-4DOI 10.1007/s12028-011-9590-zAuthors William R. Stetler, Department of Neurosurgery, University of Michigan Health System, 1500 E. Medical Center Drive, Room 3552 Taubman Center, Ann Arbor, MI 48109-5338, USAAditya S. Pandey, Department of Neurosurgery, University of Michigan Health System, 1500 E. Medical Center Drive, Room 3552 Taubman Center, Ann Arbor, MI 48109-5338, USAGeorge A. Mashour, Departmen... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5064951 Tue, 19 Jul 2011 05:50:10 +0100 5064951 http://www.medworm.com/index.php?rid=5064952&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft885280llth26574%2F Abstract  Delayed cerebral ischemia after subarachnoid hemorrhage (SAH) may be affected by a number of factors, including cerebral blood flow and oxygen delivery. Anemia affects about half of patients with SAH and is associated with worse outcome. Anemia also may contribute to the development of or exacerbate delayed cerebral ischemia. This review was designed to examine the prevalence and impact of anemia in patients with SAH and to evaluate the effects of transfusion. A literature search was made to identify original research on anemia and transfusion in SAH patients. A total of 27 articles were identified that addressed the effects of red blood cell transfusion (RBCT) on brain physiology, anemia in SAH, and clinical management with RBCT or erythropoietin. Most studies pr... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5064952 Tue, 19 Jul 2011 05:50:09 +0100 5064952 http://www.medworm.com/index.php?rid=5041798&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F4184t31n682vx632%2F Conclusions  A rule based on simple clinical criteria may be useful for stratifying the yield of MRI after ICH. If validated in further studies, such a rule could reduce the number of unnecessary MRI studies after ICH, leading to more cost-effective care. Content Type Journal ArticlePages 1-5DOI 10.1007/s12028-011-9607-7Authors Hooman Kamel, Department of Neurology and Neuroscience, Weill Cornell Medical College, 525 East 68th St, F610, New York, NY 10065, USABabak B. Navi, Department of Neurology and Neuroscience, Weill Cornell Medical College, 525 East 68th St, F610, New York, NY 10065, USAJ. Claude Hemphill, Department of Neurology, University of California, San Francisco, 505 Parnassus Avenue, Box 0114, San Francisco, CA 94143, USA Journal Neurocritical Car... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5041798 Fri, 15 Jul 2011 05:53:57 +0100 5041798 http://www.medworm.com/index.php?rid=5041797&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl2q06317m1k4348l%2F Abstract  Cerebral vasospasm and delayed cerebral ischemia account for significant morbidity and mortality after aneurysmal subarachnoid hemorrhage. While most patients are managed with triple-H therapy, endovascular treatments have been used when triple-H treatment cannot be used or is ineffective. An electronic literature search was conducted to identify English language articles published through October 2010 that addressed endovascular management of vasospasm. A total of 49 articles were identified, addressing endovascular treatment timing, intra-arterial treatments, and balloon angioplasty. Most of the available studies investigated intra-arterial papaverine or balloon angioplasty. Both have generally been shown to successfully treat vasospasm and improve neurological ... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5041797 Fri, 15 Jul 2011 05:53:57 +0100 5041797 http://www.medworm.com/index.php?rid=5041796&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv3836k7876712101%2F Abstract  Rebleeding after initial aneurysmal subarachnoid hemorrhage (SAH) can have substantial impact on overall patient outcome. While older studies have suggested rebleeding occurs in about 4% of patients during the first day after initial aneurysmal bleed, these studies may have failed to capture very early rebleeds and, consequently, underestimated the impact of rebleeding. An electronic literature search was performed to identify English-language articles published or available for review from February 1975 through October 2010. A total of 43 articles (40 original research and 3 review articles) focused on rebleeding after initial aneurysmal SAH in humans were selected for review. Although most studies supported an incidence of rebleeding ≤4%, studies investigating... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5041796 Fri, 15 Jul 2011 05:53:57 +0100 5041796 http://www.medworm.com/index.php?rid=5041799&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu673m8693057q681%2F Abstract  Cardiopulmonary complications after aneurysmal subarachnoid hemorrhage negatively affect overall morbidity and mortality. An electronic literature search was performed for English-language articles focused on cardiopulmonary complications with subarachnoid hemorrhage published through October 2010. A total of 278 citations were identified, including 72 clinical studies. In most cases, study quality was low or very low. Cardiac injury, evidenced by an elevation in troponin levels, is reported in about one-third of patients after aneurysmal subarachnoid hemorrhage. Arrhythmias also occur in about one-third of patients after subarachnoid hemorrhage. The incidence of pulmonary complications, especially neurogenic pulmonary edema, is more difficult to establish from av... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5041799 Fri, 15 Jul 2011 05:53:56 +0100 5041799 http://www.medworm.com/index.php?rid=5041800&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fwx32n73344402705%2F Abstract  An electronic literature search through August 2010 was performed to obtain articles describing fever incidence, impact, and treatment in patients with subarachnoid hemorrhage. A total of 24 original research studies evaluating fever in SAH were identified, with studies evaluating fever and outcome, temperature control strategies, and shivering. Fever during acute hospitalization for subarachnoid hemorrhage was consistently linked with worsened outcome and increased mortality. Antipyretic medications, surface cooling, and intravascular cooling may all reduce temperatures in patients with subarachnoid hemorrhage; however, benefits from cooling may be offset by negative consequences from shivering. Content Type Journal ArticlePages 1-8DOI 10.1007/s12028-011-9588... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5041800 Thu, 14 Jul 2011 06:02:53 +0100 5041800 http://www.medworm.com/index.php?rid=5031906&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2156h51648539905%2F Abstract  Seizures and seizure-like activity may occur in patients experiencing aneurysmal subarachnoid hemorrhage. Treatment of these events with prophylactic antiepileptic drugs remains controversial. An electronic literature search was conducted for English language articles describing the incidence and treatment of seizures after aneurysmal subarachnoid hemorrhage from 1980 to October 2010. A total of 56 articles were included in this review. Seizures often occur at the time of initial presentation or aneurysmal rebleeding before aneurysm treatment. Seizures occur in about 2% of patients after invasive aneurysm treatment, with a higher incidence after surgical clipping compared with endovascular repair. Non-convulsive seizures should be considered in patients with poor ... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5031906 Wed, 13 Jul 2011 06:02:56 +0100 5031906 http://www.medworm.com/index.php?rid=5031905&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa7k21636110646h8%2F Abstract  Hypovolemia is common after subarachnoid hemorrhage, and fluid imbalance negatively affects clinical outcome. Standard bedside volume measures fail to adequately assess fluid status after subarachnoid hemorrhage. An electronic literature search of original research studies evaluating fluid status after subarachnoid hemorrhage was conducted for English language articles published through October 2010. Sixteen articles were included in this review, with seven articles produced by two research groups. These studies highlight that fluid status is often affected and difficult to assess after subarachnoid hemorrhage. Both non-invasive and invasive monitors may be used to more accurately define volume status. Content Type Journal ArticlePages 1-5DOI 10.1007/s12028-01... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5031905 Wed, 13 Jul 2011 06:02:56 +0100 5031905 http://www.medworm.com/index.php?rid=5031907&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd31406362236j1x4%2F This article aims to extrapolate meaningful data for use with a population of critically ill neurologic and neurosurgical patients in the neurological intensive care unit setting. Studies were identified from the cochrane central register of controlled trials and NLM PUBMED for english articles dealing with an adult population. We also scanned bibliographies of relevant studies. The results show that H2A, sucralfate, and PPI all reduce the incidence of UGIB in neurocritically ill patients, but H2A blockers may cause encephalopathy and interact with anticonvulsant drugs, and have been associated with higher rates of nosocomial pneumonias, but causation remains unproven and controversial. For these reasons, we advocate against routine use of H2A for GI prophylaxis in neurocritical patie... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5031907 Tue, 12 Jul 2011 06:10:56 +0100 5031907 http://www.medworm.com/index.php?rid=5031908&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv742lv971u3r0436%2F Abstract  Delayed cerebral ischemia (DCI) after subarachnoid hemorrhage can be evaluated using clinical assessment, non-invasive and invasive techniques. An electronic literature search was conducted on English-language articles investigating DCI in human subjects with subarachnoid hemorrhage. A total of 31 relevant papers were identified evaluating the role of clinical assessment, transcranial Doppler, computed tomographic angiography, and computed tomographic perfusion. Clinical assessment by bedside evaluations is limited, especially in patients initially in poorer clinical condition or who are receiving sedative medication for whom deterioration may be more difficult to identify. Transcranial Doppler is a useful screening tool for middle cerebral artery vasospasm, with ... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5031908 Tue, 12 Jul 2011 06:10:55 +0100 5031908 http://www.medworm.com/index.php?rid=5031909&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc51g01270531733q%2F Abstract  Prophylactic use of hypervolemia and hypertension is believed to present an option to decrease the incidence of symptomatic vasospasm after aneurysmal subarachnoid hemorrhage and improve neurologic outcome. A Medline literature search was conducted to review available evidence regarding volume management after subarachnoid hemorrhage. Quality of selected studies was evaluated, using the standardized GRADE system. Eleven studies focused on prophylactic hypervolemic therapy after aneurysmal subarachnoid hemorrhage were identified, including four randomized controlled trials. Available studies showed a large heterogeneity in physiologic treatment goals and interventions applied. The oldest and smallest randomized controlled trial suggested a positive effect, but had ... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5031909 Tue, 12 Jul 2011 06:10:53 +0100 5031909 http://www.medworm.com/index.php?rid=5031911&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk385k6u4113r2j47%2F Abstract  Several non-invasive and invasive modalities have been used to monitor patients for cerebral ischemia after subarachnoid hemorrhage. A literature search was performed to identify original research studies testing monitors that may be used in addition to the standard measures of brain function and cerebral blood flow. Fifty observational studies were identified that evaluated the role of electroencephalography, brain tissue oxygenation monitoring, cerebral microdialysis, thermal diffusion flowmetry, or near-infrared spectroscopy in patients after subarachnoid hemorrhage. Content Type Journal ArticlePages 1-6DOI 10.1007/s12028-011-9583-yAuthors Daniel Hänggi, Department of Neurosurgery, Heinrich-Heine-University, Düsseldorf, Moorenstr. 5, 40225 Düsseldorf, G... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5031911 Tue, 12 Jul 2011 06:10:52 +0100 5031911 http://www.medworm.com/index.php?rid=5031910&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu2p8572630257n52%2F Abstract  Magnesium offers theoretic vascular and neuroprotective benefits for patients with subarachnoid hemorrhage. An electronic literature search was conducted to identify original research studies describing intravenous magnesium treatment in patients with SAH published in English between January 1990 and October 2010. Seventeen articles were identified and reviewed, including one phase III randomized-controlled clinical trial and six phase II randomized-controlled trials. Study quality was low for most of the included studies, with the phase III trial considered to be of moderate quality. Due to inconsistently reported benefits and the occurrence of side effects, phase II data suggested that intravenous magnesium for SAH provided either no overall net benefit or uncer... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5031910 Tue, 12 Jul 2011 06:10:52 +0100 5031910 http://www.medworm.com/index.php?rid=5031913&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft5170184157m6313%2F Abstract  Hyponatremia is the most common electrolyte imbalance seen in patients with aneurysmal subarachnoid hemorrhage, occurring in one-third to one-half of patients. Hyponatremia may be caused by cerebral salt wasting and by the syndrome of inappropriate secretion of antidiuretic hormone or a combination of both. Limited data are available describing hyponatremia treatment in subarachnoid hemorrhage patients. A Medline search was performed for English-language manuscripts describing original research in the treatment for hyponatremia in patients with aneurysmal subarachnoid hemorrhage. Seven appropriate articles were identified as followed: three testing fludrocortisone, two hydrocortisone, and one each for hypertonic saline and 5% albumin. Data quality for treatment ef... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5031913 Tue, 12 Jul 2011 06:10:51 +0100 5031913 http://www.medworm.com/index.php?rid=5031912&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft173574vk31jx809%2F Conclusions  Because the regression between VC and P imax was linear rather than curvilinear, P imax was not more sensitive than VC for early detection of respiratory muscle failure in patients hospitalized in ICU for GBS and MG exacerbation. Therefore, VC remains well suited to assess acute respiratory muscle failure and P imax gives poor additional information. Content Type Journal ArticlePages 1-4DOI 10.1007/s12028-011-9575-yAuthors Hélène Prigent, Physiologie—Explorations Fonctionnelles, Service de Réanimation Médicale, et Centre d’Innovations Technologiques UMR 805, Hôpital Raymond Poincaré, AP-HP, 92380 Garches, FranceDavid Orlikowski, Physiologie—Explorations Fonctionnelles, Service de Réanimation Médicale, et Centre d’Innovations Technologiq... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5031912 Tue, 12 Jul 2011 06:10:51 +0100 5031912 http://www.medworm.com/index.php?rid=5031915&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr1n840mp84528178%2F Abstract  Dabigatran etexilate is an oral, reversible direct thrombin inhibitor and has been recently approved for the prevention of stroke in patients with non-valvular atrial fibrillation. This review describes the incidence and management of stroke and related complications in patients on dabigatran etexilate. Dabigatran is a rapidly acting, and highly selective and reversible inhibitor of thrombin. It also has a potent inhibitory effect on thrombin-induced platelet aggregation, making it effective in preventing both venous and arterial thrombosis. The activated partial thromboplastin time, ecarin clotting time and thrombin time are sensitive tests to evaluate the anticoagulant effects of dabigatran. The rate of ischemic stroke is significantly lower in patients on 150&n... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5031915 Tue, 12 Jul 2011 06:10:49 +0100 5031915 http://www.medworm.com/index.php?rid=5031914&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa3073kwr715865m3%2F Abstract  Although clinicians are generally advised to use prophylactic therapy to reduce the risk for developing deep venous thrombosis in patients after repair of ruptured aneurysms, limited data are available to guide specific therapeutic decisions. An electronic literature search was conducted to identify English-language articles that addressed prophylactic treatment for deep venous thrombosis after subarachnoid hemorrhage published between 1980 and March 2011. A total of 12 articles were included in this review, including seven original research studies and one meta-analysis. The incidence of deep venous thrombosis varied among studies, with the highest incidence reported with prospective ultrasound screening. Poor-grade patients are at highest risk. Mechanical prophy... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5031914 Tue, 12 Jul 2011 06:10:49 +0100 5031914 http://www.medworm.com/index.php?rid=5031917&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fqm01v24285238230%2F Abstract  Ischemia is a common cause of secondary neuronal injury after aneurysmal subarachnoid hemorrhage. An electronic literature search was conducted to identify clinical signs and laboratory data that could serve as predictors for delayed cerebral ischemia and define triggers for additional diagnostic testing or more aggressive intervention. Fifteen articles describing original research that included some discussion of triggers were identified and reviewed. Quality of evidence was considered very low to moderate for included studies. Using data from these studies and expert opinion, a variety of clinical signs and monitoring data were identified as potentially useful triggers for additional tests or aggressive treatments. These data were used to develop a sequence that... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5031917 Tue, 12 Jul 2011 06:10:47 +0100 5031917 http://www.medworm.com/index.php?rid=5031916&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq94qrh831tx413w5%2F Conclusions  In patients with severe brain injury, obesity was found to be an independent predictor of compromised PbtO2. This effect may be mediated through obesity-related pulmonary dysfunction and inadequate compensatory mechanisms. Content Type Journal ArticlePages 1-8DOI 10.1007/s12028-011-9576-xAuthors Monisha A. Kumar, Department of Neurosurgery, Clinical Research Division, University of Pennsylvania Medical Center, Philadelphia, PA, USARishi Chanderraj, Department of Neurosurgery, Clinical Research Division, University of Pennsylvania Medical Center, Philadelphia, PA, USARyan Gant, Department of Neurosurgery, Clinical Research Division, University of Pennsylvania Medical Center, Philadelphia, PA, USAChristi Butler, Department of Neurosurgery, Clinical Research ... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5031916 Tue, 12 Jul 2011 06:10:47 +0100 5031916 http://www.medworm.com/index.php?rid=5031918&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F074j3868300v20t3%2F Abstract  Delayed cerebral ischemia occurs in about 30% of patients during the first 2 weeks after subarachnoid hemorrhage, and can result in substantial disability and death. Research studies investigating the incidence of delayed cerebral ischemia and strategies for prevention and treatment are hampered by inconsistent use of terminology and definitions for this complication, and by reliance on indirect surrogate markers of ischemia. A literature review was conducted to search for studies that addressed the issue of inconsistent definitions of delayed cerebral ischemia through December 2010. A total of four studies were identified. Original research studies and consensus panel recommendations for definitions support limiting the use of combined measures that include ... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5031918 Tue, 12 Jul 2011 06:10:45 +0100 5031918 http://www.medworm.com/index.php?rid=5011133&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv8466g2618242558%2F Conclusion  Management of brainstem stroke in children requires coordination of neurology, critical care, and interventional radiology services. Delayed intra-arterial thrombolysis and vertebral artery coiling can be successfully used to treat basilar artery occlusion and prevent the recurrence of brainstem ischemia in children. Content Type Journal ArticlePages 1-5DOI 10.1007/s12028-011-9579-7Authors John Condie, Department of Pediatrics, Division of Neurology, Northwestern University Feinberg School of Medicine, No. 51, Children’s Memorial Hospital, 2300 Children’s Plaza, Chicago, IL 60614-3394, USAAli Shaibani, Departments of Radiology and Neurosurgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USAMark S. Wainwright, Department of Ped... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5011133 Wed, 06 Jul 2011 05:56:51 +0100 5011133 http://www.medworm.com/index.php?rid=5001290&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff7x793020k1x1367%2F Conclusions  There is considerable lack of agreement, even among stroke specialists, in selecting acute ischemic stroke patients for endovascular treatment based on CT-P changes. This mandates a careful evaluation of CT-P for patient selection before widespread adoption. Content Type Journal ArticlePages 1-7DOI 10.1007/s12028-011-9577-9Authors Ameer E. Hassan, Zeenat Qureshi Stroke Research Center, University of Minnesota, 12-100 PWB, 516 Delaware St. SE, Minneapolis, MN 55455, USAHaralabos Zacharatos, Zeenat Qureshi Stroke Research Center, University of Minnesota, 12-100 PWB, 516 Delaware St. SE, Minneapolis, MN 55455, USASaqib A. Chaudhry, Zeenat Qureshi Stroke Research Center, University of Minnesota, 12-100 PWB, 516 Delaware St. SE, Minneapolis, MN 55455, USAM. Fa... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=5001290 Sat, 02 Jul 2011 05:44:04 +0100 5001290 http://www.medworm.com/index.php?rid=4994580&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2631755g70745441%2F Conclusion  This study demonstrates that 23.4% HTS bolus is effective for the reduction of elevated ICP in patients with severe TBI even in the presence of high serum and CSF osmolalities. Content Type Journal ArticlePages 1-7DOI 10.1007/s12028-011-9574-zAuthors Eduardo Paredes-Andrade, Division of Neurosurgery, Department of Surgery, Hennepin County Medical Center, 701 Park Avenue, Minneapolis, MN 55415, USACraig A. Solid, Chronic Disease Research Group, Analytical Services, Minneapolis Medical Research Foundation, Minneapolis, MN, USASarah B. Rockswold, Division of Neurosurgery, Department of Surgery, Hennepin County Medical Center, 701 Park Avenue, Minneapolis, MN 55415, USARick M. Odland, Department of Otolaryngology, Hennepin County Medical Center, Minneapolis, M... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4994580 Fri, 01 Jul 2011 17:43:21 +0100 4994580 http://www.medworm.com/index.php?rid=4994581&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F9727n78407r8u180%2F Conclusions  In patients with small-to-moderate-sized hematomas, change in PHH was a poor measure of brain edema in the first week following ICH. A small degree of bihemispheric brain swelling occurred, but was of little clinical significance. Content Type Journal ArticlePages 1-6DOI 10.1007/s12028-011-9578-8Authors Allyson R. Zazulia, Department of Neurology and Neurological Surgery, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8111, St. Louis, MO 63110, USATom O. Videen, Department of Neurology and Neurological Surgery, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8111, St. Louis, MO 63110, USAMichael N. Diringer, Department of Neurology and Neurological Surgery, Washington University School of Medicine, 66... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4994581 Fri, 01 Jul 2011 17:43:19 +0100 4994581 http://www.medworm.com/index.php?rid=4987565&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F9u5v473u566x8461%2F Conclusion  The presentation of intracranial hemorrhage with an isolated prolonged aPTT is concerning for an acquired hemophilia with FVIII deficiency. Other causes of isolated prolonged aPTT such as a lupus anticoagulant must also be considered. Preoperative identification and work-up of the coagulation abnormality is essential to guide initial treatment. Content Type Journal ArticlePages 1-5DOI 10.1007/s12028-010-9489-0Authors Dejan Micic, University of Wisconsin School of Medicine and Public Health, Madison, WI, USAEliot C. Williams, Department of Internal Medicine, Section of Hematology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USAJoshua E. Medow, Department of Neurosurgery, University of Wisconsin School of Medicine and Public H... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4987565 Wed, 29 Jun 2011 05:59:56 +0100 4987565 http://www.medworm.com/index.php?rid=4971633&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F52086043077m8q00%2F Conclusion  Ultrasound-guided bedside EVD placement allows EVD trajectories to be customized based on real-time information to accommodate for distorted and dynamic anatomy of the brain and its ventricles. Content Type Journal ArticlePages 1-5DOI 10.1007/s12028-011-9571-2Authors Scott B. Phillips, Department of Neurosurgery, Henry Ford Hospital, 2799 West Grand Blvd, Detroit, 48202 MI, USAMarilyn Gates, Department of Neurosurgery, Henry Ford Hospital, 2799 West Grand Blvd, Detroit, 48202 MI, USASatish Krishnamurthy, Department of Neurosurgery, Upstate Medical University, Syracuse, NY, USA Journal Neurocritical CareOnline ISSN 1556-0961Print ISSN 1541-6933 (Source: Neurocritical Care) Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4971633 Tue, 21 Jun 2011 20:39:15 +0100 4971633 http://www.medworm.com/index.php?rid=4971634&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc28148616623098h%2F Conclusions  Systolic flow indices (Sx and Sxa) demonstrated a stronger association with outcome than the mean flow indices (Mx and Mxa), irrespective of whether CPP or ABP was used for calculation. Content Type Journal ArticlePages 1-8DOI 10.1007/s12028-011-9572-1Authors Karol P. Budohoski, Division of Neurosurgery, Department of Clinical Neurosciences, Addenbrooke’s Hospital, University of Cambridge, Hills Road, Cambridge, CB2 0QQ UKMatthias Reinhard, Department of Neurology, Neurocenter, University of Freiburg, Hugstetter Str. 49, 79095 Freiburg, GermanyMarcel J. H. Aries, Department of Neurology, University Medical Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The NetherlandsZofia Czosnyka, Division of Neurosurgery, Department of Clinical Neurosciences, Add... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4971634 Tue, 21 Jun 2011 20:39:13 +0100 4971634 http://www.medworm.com/index.php?rid=4955899&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F043pv1n192725q49%2F Conclusions  Although handling of IV fluid administration was not an independent predictor of mortality or new stroke, patients with early positive fluid balance had worse clinical presentation and had greater resource use during the hospital course. Content Type Journal ArticlePages 1-8DOI 10.1007/s12028-011-9573-0Authors Ross P. Martini, Department of Anesthesiology and Pain Medicine, Harborview Medical Center, University of Washington, Washington, USASteven Deem, Department of Anesthesiology and Pain Medicine, Harborview Medical Center, University of Washington, Washington, USAMarcia Brown, Department of Anesthesiology and Pain Medicine, Harborview Medical Center, University of Washington, Washington, USAMichael J. Souter, Department of Anesthesiology and Pain Medi... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4955899 Mon, 20 Jun 2011 14:13:49 +0100 4955899 http://www.medworm.com/index.php?rid=4947448&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr47t6746174467g8%2F Conclusion  The decision to place dual EVDs is generally reserved for large IVH (>40 ml) with casting and mass effect. The use of dual simultaneous catheters may increase clot resolution with or without adjunctive thrombolytic therapy. Content Type Journal ArticlePages 1-7DOI 10.1007/s12028-011-9569-9Authors Holly E. Hinson, Division of Neurosciences Critical Care, Johns Hopkins University School of Medicine, Meyer 8-140, 600 N. Wolfe St., Baltimore, MD, USAEric Melnychuk, Division of Brain Injury Outcomes, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USAJohn Muschelli, Division of Brain Injury Outcomes, Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USADaniel F. Hanley, Division of ... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4947448 Fri, 17 Jun 2011 10:55:32 +0100 4947448 http://www.medworm.com/index.php?rid=4947449&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp6tg38894j197102%2F Abstract  Advanced hemodynamic monitoring is necessary for many patients with acute brain and/or spinal cord injury. Optimizing cerebral and systemic physiology requires multi-organ system function monitoring. Hemodynamic manipulations are cardinal among interventions to regulate cerebral perfusion pressure and cerebral blood flow. The pulmonary artery catheter is not any more the sole tool available; less invasive and potentially more accurate methodologies have been developed and employed in the operating room and among diverse critically ill populations. These include transpulmonary thermodilution, arterial pressure pulse contour, and waveform analysis and bedside critical care ultrasound. A thorough understanding of hemodynamics and of the available monitoring modalitie... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4947449 Thu, 16 Jun 2011 05:55:29 +0100 4947449 http://www.medworm.com/index.php?rid=4947450&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp58101075521hr30%2F Conclusions  There was great variability in the presence of pneumonia among neurosurgical patients, depending on the criteria used. Our results support the idea that a more exact method for pneumonia diagnosis should be implemented to obtain more reliable results in this important infection of hospitalized patients, which is also used for benchmarking purposes. Furthermore, it seems important to treat all clinically suspected pneumonia cases whether or not the surveillance criteria are fulfilled. Content Type Journal ArticlePages 1-7DOI 10.1007/s12028-011-9570-3Authors Petri Kuusinen, Department of Anesthesiology and Division of Intensive Care, Oulu University Hospital, P.O. Box 21, 90029 OYS, Oulu, FinlandTero Ala-Kokko, Department of Anesthesiology and Division of... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4947450 Wed, 15 Jun 2011 05:53:12 +0100 4947450 http://www.medworm.com/index.php?rid=4939884&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F5h3314n7426625l2%2F Conclusions  In 83, 7% of patients who die in the mixed ICU life-sustaining treatment is withdrawn. Severe cerebral damage was the leading reason to withdraw life-sustaining treatment. Content Type Journal ArticlePages 1-6DOI 10.1007/s12028-011-9567-yAuthors Martijn A. Verkade, Department of Intensive Care Medicine, Erasmus University Medical Center Rotterdam, Room H 324, P.O. Box 2040, 3000 CA Rotterdam, The NetherlandsJelle L. Epker, Department of Intensive Care Medicine, Erasmus University Medical Center Rotterdam, Room H 324, P.O. Box 2040, 3000 CA Rotterdam, The NetherlandsMariska D. Nieuwenhoff, Department of Intensive Care Medicine, Erasmus University Medical Center Rotterdam, Room H 324, P.O. Box 2040, 3000 CA Rotterdam, The NetherlandsJan Bakker, Department o... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4939884 Fri, 10 Jun 2011 06:25:21 +0100 4939884 http://www.medworm.com/index.php?rid=4915545&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy059448g6q481885%2F Conclusion  HFOV is associated with less hemodynamic compromise than VCV, even when using small tidal volumes and low mean airway pressures. It does not impair cerebral perfusion or tissue oxygenation in animals with AICH, and could, therefore, be a useful ventilatory strategy to prevent lung failure in patients with traumatic brain injury. Content Type Journal ArticlePages 1-12DOI 10.1007/s12028-011-9566-zAuthors Jan Florian Heuer, Department of Anaesthesiology, Emergency- and Intensive Care Medicine, University of Göttingen Medical School, Göttingen, GermanyPhilip Sauter, Department of Anaesthesiology, Emergency- and Intensive Care Medicine, University of Göttingen Medical School, Göttingen, GermanyJürgen Barwing, Department of Anaesthesiology, Emergency- and ... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4915545 Tue, 07 Jun 2011 05:47:20 +0100 4915545 http://www.medworm.com/index.php?rid=4896814&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc773605520256774%2F Conclusions  PbtO2 monitoring accurately describes tissue oxygenation but does not disclose whether the oxygen delivery is sufficient for maintaining cerebral energy metabolism. Accordingly, it may not be possible to define a threshold level for PbtO2 below which energy failure and permanent tissue damage occurs. Content Type Journal ArticlePages 1-8DOI 10.1007/s12028-011-9563-2Authors Troels Halfeld Nielsen, Department of Neurosurgery, Odense University Hospital, Sdr. Boulevard 29, 5000 Odense C, DenmarkSusanne I. Engell, Faculty of Health Science, University of Southern Denmark, Odense C, DenmarkRikke Aagaard Johnsen, Faculty of Health Science, University of Southern Denmark, Odense C, DenmarkMette K. Schulz, Department of Neurosurgery, Odense University Hospital, S... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4896814 Fri, 03 Jun 2011 06:01:08 +0100 4896814 http://www.medworm.com/index.php?rid=4896815&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk5732717h503717v%2F Conclusions  NCSE is common in comatose post-cardiac arrest subjects receiving TH. Most seizures occur within the first 8 h of cEEG recording and within the first 12 h after resuscitation from cardiac arrest. Outcomes are poor in those who experience NCSE. Content Type Journal ArticlePages 1-9DOI 10.1007/s12028-011-9565-0Authors Jon C. Rittenberger, Department of Emergency Medicine, University of Pittsburgh, Iroquois Building, Suite 400A, 3600 Forbes Avenue, Pittsburgh, PA 15261, USAAlexandra Popescu, Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USARichard P. Brenner, Department of Neurology, University of Pittsburgh, Pittsburgh, PA, USAFrancis X. Guyette, Department of Emergency Medicine, University of Pittsburgh, Iroquois Building, Su... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4896815 Fri, 03 Jun 2011 06:01:07 +0100 4896815 http://www.medworm.com/index.php?rid=4896816&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff7813x6xr15347m6%2F Conclusions  TCD identification of vasospasm after day 10 is rare. Stroke is more likely to result from poor detection than from brevity of TCD monitoring. Improved or alternative monitoring is needed to effectively identify ischemia and prevent stroke. Content Type Journal ArticlePages 1-6DOI 10.1007/s12028-011-9564-1Authors Chad M. Miller, Department of Neurosurgery, Cedars-Sinai Medical Center, 8631 West Third Street, Suite 800E, Los Angeles, CA 90048, USADavid Palestrant, Department of Neurosurgery, Cedars-Sinai Medical Center, 8631 West Third Street, Suite 800E, Los Angeles, CA 90048, USAWouter I. Schievink, Department of Neurosurgery, Cedars-Sinai Medical Center, 8631 West Third Street, Suite 800E, Los Angeles, CA 90048, USAMichael J. Alexander, Department of Ne... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4896816 Thu, 02 Jun 2011 05:56:36 +0100 4896816 http://www.medworm.com/index.php?rid=4896817&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp74w360417266050%2F Abstract  The December 2003 report from the National Institute of Neurological Disorders and Stroke (NINDS) Workshop on priorities for clinical research in intracerebral hemorrhage (ICH) recommended clinical trials for evaluation of blood pressure management in acute ICH as a leading priority. The Special Writing Group of the Stroke Council of the American Heart Association in 1999 and 2007 emphasized the need for clinical trials to ensure evidence-based treatment of acute hypertensive response in ICH. To address important gaps in knowledge, we conducted a pilot study funded by the NINDS, Antihypertensive Treatment of Acute Cerebral Hemorrhage (ATACH) I Trial, during 2004–2008 to determine the appropriate level of systolic blood pressure (SBP) reduction. We now have initi... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4896817 Mon, 30 May 2011 17:07:23 +0100 4896817 http://www.medworm.com/index.php?rid=4896818&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj331531u1344r157%2F Conclusions  Postischemic neuronal survival was increased with 1.8 MAC compared with 0.45 MAC sevoflurane. Therefore, experimental models of cerebral ischemia should account for neuroprotective effects of sevoflurane with increasing concentrations. To ensure minimal interference of sevoflurane on neuronal survival, a low inspired concentration should be used and fluctuations in the depth of anesthesia should be limited. Content Type Journal ArticlePages 1-8DOI 10.1007/s12028-011-9562-3Authors Irina Lasarzik, Department of Anesthesiology, Medical Center of the Johannes Gutenberg-University, Langenbeckstrasse 1, 55131 Mainz, GermanyRüdiger R. Noppens, Department of Anesthesiology, Medical Center of the Johannes Gutenberg-University, Langenbeckstrasse 1, 551... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4896818 Fri, 27 May 2011 06:01:55 +0100 4896818 http://www.medworm.com/index.php?rid=4896819&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl342118523002632%2F Conclusions  Clinicians should be aware that the oculocardiac reflex might mimic signs of intracranial hypertension in patients with combined facial and cerebral trauma. Content Type Journal ArticlePages 1-3DOI 10.1007/s12028-011-9560-5Authors Joshua M. Levine, Department of Neurology, Hospital of the University of Pennsylvania, University of Pennsylvania, 3 West Gates Building, 3400 Spruce Street, Philadelphia, PA 19104, USAEsther Bisker, Department of Ophthalmology, University of Pennsylvania, Philadelphia, USASteven L. Galetta, Department of Neurology, Hospital of the University of Pennsylvania, University of Pennsylvania, 3 West Gates Building, 3400 Spruce Street, Philadelphia, PA 19104, USAMonisha A. Kumar, Department of Neurology, Hospital of the University of P... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4896819 Tue, 24 May 2011 05:53:11 +0100 4896819 http://www.medworm.com/index.php?rid=4896820&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F81rxg226l6151j41%2F Conclusion  SBD exam is easier, faster to perform, with no brain function recovery and leads to similar donation rates, equivalent or better organ function status at the time of BD and lower cost than conventional DBD exams. Content Type Journal ArticlePages 1-7DOI 10.1007/s12028-011-9561-4Authors Panayiotis N. Varelas, Department of Neurology, Henry Ford Hospital, Detroit, MI, USAMohammed Rehman, Department of Neurology, Henry Ford Hospital, Detroit, MI, USATamer Abdelhak, Department of Neurology, Henry Ford Hospital, Detroit, MI, USAAashish Patel, Department of Neurology, Henry Ford Hospital, Detroit, MI, USAVivek Rai, Department of Neurology, Henry Ford Hospital, Detroit, MI, USAAmy Barber, Transplant Institute, Henry Ford Hospital, Detroit, MI, USASusan Sommer, Gi... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4896820 Sat, 21 May 2011 23:22:02 +0100 4896820 http://www.medworm.com/index.php?rid=4896821&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx544052h107p1144%2F Conclusions  Terson’s syndrome occurs frequently following SAH, although it is under-reported. Suspected visual loss following SAH should prompt a search for Terson’s syndrome by funduscopy, as its presence is an adverse prognostic factor. Content Type Journal ArticlePages 1-5DOI 10.1007/s12028-011-9555-2Authors Anhar Hassan, Department of Neurology, Mayo Clinic, Rochester, MN 55905, USAGiuseppe Lanzino, Department of Neurosurgery, Mayo Clinic, Rochester, MN 55905, USAEelco F. M. Wijdicks, Department of Critical Care Neurology, Mayo Clinic, Rochester, MN 55905, USAAlejandro A. Rabinstein, Department of Critical Care Neurology, Mayo Clinic, Rochester, MN 55905, USAKelly D. Flemming, Department of Neurology, Mayo Clinic, Rochester, MN 55905, USA Journal Neuro... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4896821 Sat, 21 May 2011 23:22:00 +0100 4896821 http://www.medworm.com/index.php?rid=4856371&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg85805w761552281%2F Conclusions  Based on these results the authors conclude that elevated CSF levels of sFlt1 and sEng herald the occurrence of symptomatic VS post SAH. Content Type Journal ArticlePages 1-5DOI 10.1007/s12028-011-9559-yAuthors Fernando D. Testai, Department of Neurology of the University of Illinois at Chicago, 912 S Wood Street (MC-796), Chicago, IL 60612-7330, USAVenkatesh Aiyagari, Department of Neurology of the University of Illinois at Chicago, 912 S Wood Street (MC-796), Chicago, IL 60612-7330, USAMaureen Hillmann, Department of Neurology of the University of Illinois at Chicago, 912 S Wood Street (MC-796), Chicago, IL 60612-7330, USASepideh Amin-Hanjani, Department of Neurosurgery of the University of Illinois at Chicago, 912 South Wood Street (MC 799), Chicago, I... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4856371 Wed, 18 May 2011 06:18:01 +0100 4856371 http://www.medworm.com/index.php?rid=4856372&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fyx9pw7761708433k%2F Content Type Journal ArticlePages 1-3DOI 10.1007/s12028-011-9558-zAuthors Linda C. Wendell, Department of Neurology and Neurosurgery, Rhode Island Hospital/Warren Alpert School of Medicine at Brown University, Providence, RI 02906, USAW. Andrew Kofke, Department of Anesthesiology and Critical Care and Neurosurgery, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, USA Journal Neurocritical CareOnline ISSN 1556-0961Print ISSN 1541-6933 (Source: Neurocritical Care) Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4856372 Tue, 17 May 2011 05:58:22 +0100 4856372 http://www.medworm.com/index.php?rid=4833551&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F0251513607511132%2F Conclusions  Decline in serum glucose concentration correlated with reduction in proportion of subjects with hematoma expansion and poor clinical outcome. These results provide a justification for a randomized controlled clinical trial to evaluate the efficacy of aggressive serum glucose reduction in reducing death and disability among patients with ICH. Content Type Journal ArticlePages 1-8DOI 10.1007/s12028-011-9541-8Authors Adnan I. Qureshi, Zeenat Qureshi Stroke Research Center, Department of Neurology, University of Minnesota, 12-100 PWB, 516 Delaware St. SE, Minneapolis, MN 55455, USAYuko Y. Palesch, Division of Biostatistics and Epidemiology, Medical University of South Carolina, Charleston, SC, USARenee Martin, Division of Biostatistics and Epidemiology, Medi... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4833551 Sat, 14 May 2011 16:01:17 +0100 4833551 http://www.medworm.com/index.php?rid=4833552&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp501036451741q81%2F Conclusions  After correction for ICH volume and location, aspirin use or reduced platelet activity was associated with similar increased odds for craniotomy. Content Type Journal ArticlePages 1-5DOI 10.1007/s12028-011-9557-0Authors Andrew M. Naidech, Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USANeil F. Rosenberg, Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USARichard A. Bernstein, Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USAH. Hunt Batjer, Department of Neurosurgery, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA Journal Neurocritical CareOnline ISSN 1556-0961Print ISSN ... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4833552 Fri, 13 May 2011 05:44:29 +0100 4833552 http://www.medworm.com/index.php?rid=4833553&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fnh132126r151h421%2F Conclusion  It is unlikely that serum TNF-α or TNF-α genotype play an important role in the occurrence of DCI after SAH. Content Type Journal ArticlePages 1-5DOI 10.1007/s12028-011-9556-1Authors Martine M. A. Beeftink, Utrecht Stroke Center, Rudolf Magnus Institute of Neuroscience, Department of Neurology, University Medical Center Utrecht, Utrecht, The NetherlandsYnte M. Ruigrok, Utrecht Stroke Center, Rudolf Magnus Institute of Neuroscience, Department of Neurology, University Medical Center Utrecht, Utrecht, The NetherlandsGabriel J. E. Rinkel, Utrecht Stroke Center, Rudolf Magnus Institute of Neuroscience, Department of Neurology, University Medical Center Utrecht, Utrecht, The NetherlandsWalter M. van den Bergh, Utrecht Stroke Center, Rudolf Magnus Institute of Ne... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4833553 Thu, 12 May 2011 18:56:49 +0100 4833553 http://www.medworm.com/index.php?rid=4823372&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fdr18152366460423%2F The objectives of this study were to determine if clinical and physiological benefits of high-frequency oscillatory ventilation (HFOV) exist compared to conventional ventilation and to determine what data there are on the effects of HFOV on cerebral perfusion pressure and intracranial pressure. Systematic review was designed. An optimally sensitive search strategy was used that included; OVID MEDLINE, OVID EMBASE, Cochrane Clinical Trials Register, and hand searching of references of retrieved articles and proceedings of meetings. Study selection includes published randomized controlled trials comparing HFOV with conventional ventilation in adults with ARDS and observational studies of the use of HFOV in adults with ARDS and traumatic brain injury (TBI). Both authors reviewed all tri... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4823372 Wed, 11 May 2011 06:27:28 +0100 4823372 http://www.medworm.com/index.php?rid=4807706&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa4170169ur357687%2F Conclusions  Cerebrovascular events are early and serious complications that should be considered in bevacizumab-treated patients who present with an acute neurologic deterioration. Content Type Journal ArticlePages 1-7DOI 10.1007/s12028-011-9552-5Authors Raymond C. S. Seet, Department of Neurology, Mayo Clinic, W8B, 200 First Street SW, Rochester, MN 55905, USAAlejandro A. Rabinstein, Department of Neurology, Mayo Clinic, W8B, 200 First Street SW, Rochester, MN 55905, USAPaul E. Lindell, Department of Radiology, Mayo Clinic, Rochester, MinnesotaJoon H. Uhm, Department of Neurology, Mayo Clinic, W8B, 200 First Street SW, Rochester, MN 55905, USAEelco F. Wijdicks, Department of Neurology, Mayo Clinic, W8B, 200 First Street SW, Rochester, MN 55905, USA Journal Ne... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4807706 Fri, 06 May 2011 05:53:47 +0100 4807706 http://www.medworm.com/index.php?rid=4807707&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh647767840650526%2F Content Type Journal ArticlePages 1-1DOI 10.1007/s12028-011-9551-6Authors Andrew M. Naidech, Department of Neurology, Northwestern University, 710 N Lake Shore Drive, 11th floor, Chicago, IL 60611, USAJames Paparello, Department of Internal Medicine, Northwestern University, 710 N Lake Shore Drive, 11th floor, Chicago, IL 60611, USAStorm M. Liebling, Department of Neurology, Northwestern University, 710 N Lake Shore Drive, 11th floor, Chicago, IL 60611, USASarice L. Bassin, Department of Neurology, Northwestern University, 710 N Lake Shore Drive, 11th floor, Chicago, IL 60611, USAKimberly Levasseur, Northwestern Memorial Hospital, 251 E Huron, Chicago, IL 60611, USAMark J. Alberts, Department of Neurology, Northwestern University, 710 N Lake Shore Drive, 11th floor, Chicago, IL 60... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4807707 Fri, 06 May 2011 05:53:46 +0100 4807707 http://www.medworm.com/index.php?rid=4791269&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F385l1363w3128025%2F Conclusions  Symptomatic PRLVT is not uncommon in critically ill patients admitted to the neurological ICU. Future research should focus on indentifying modifiable risk factors for PRLVT and on comparing major cumulative complication rates between PICCs and CICVCs. Content Type Journal ArticlePages 1-7DOI 10.1007/s12028-011-9554-3Authors Jeffrey J. Fletcher, Department of Neurosurgery, University of Michigan, 3552 Taubman Health Care Center, 1500 E. Medical Center Drive, Ann Arbor, MI 48109-5338, USAWilliam Stetler, Department of Neurosurgery, University of Michigan, 3552 Taubman Health Care Center, 1500 E. Medical Center Drive, Ann Arbor, MI 48109-5338, USAThomas J. Wilson, Department of Neurosurgery, University of Michigan, 3552 Taubman Health Care Center, 1500 E. M... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4791269 Wed, 04 May 2011 05:45:42 +0100 4791269 http://www.medworm.com/index.php?rid=4784140&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F448h43700761204x%2F Conclusions  Nonaneurysmal perimesencephalic SAH may have a “malignant” course requiring close neurocritical care monitoring and multiple clinical and endovascular interventions. Moreover, large cisternal hemorrhage was correlated with the development of DCI in this patient with non-aneurysmal SAH. Content Type Journal ArticlePages 1-5DOI 10.1007/s12028-011-9548-1Authors Edgar A. Samaniego, Baptist Cardiac and Vascular Institute, 8900 N Kendall Drive, Miami, FL 33176, USAGuilherme Dabus, Baptist Cardiac and Vascular Institute, 8900 N Kendall Drive, Miami, FL 33176, USAKarel Fuentes, Baptist Cardiac and Vascular Institute, 8900 N Kendall Drive, Miami, FL 33176, USAItalo Linfante, Baptist Cardiac and Vascular Institute, 8900 N Kendall Drive, Miami, FL 33176, USA ... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4784140 Fri, 29 Apr 2011 05:42:25 +0100 4784140 http://www.medworm.com/index.php?rid=4784141&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fhg37553544k61370%2F Conclusions  The FOUR score is a valid tool with good inter-rater reliability that is comparable to the GLS/GCS in predicting outcome. It offers the advantage to be performable in intubated patients and to identify non-verbal signs of consciousness by assessing visual pursuit, and hence minimal signs of consciousness (11% in this study), not assessed by GLS/GCS scales. Content Type Journal ArticlePages 1-7DOI 10.1007/s12028-011-9547-2Authors Marie-Aurélie Bruno, Coma Science Group, Cyclotron Research Centre and Neurology Department, University and University Hospital of Liège, Sart-Tilman (B30), 4000 Liège, BelgiumDidier Ledoux, Coma Science Group, Cyclotron Research Centre and Neurology Department, University and University Hospital of Liège, Sart-Tilman (B30), ... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4784141 Wed, 27 Apr 2011 10:55:32 +0100 4784141 http://www.medworm.com/index.php?rid=4784142&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fth32jk5130295812%2F Conclusions  Low pressure hydrocephalus is a challenging diagnosis. The genesis of LPH was associated with a drop in EVD output, symptomatic ventriculomegaly, and a remarkable absence of intracranial hypertension. When LPH was treated with the sub-zero method, a ‘diuresis’ of CSF ensued. These observations support a Darcy’s flux of brain interstitial fluid due to altered brain poroelastance; in simpler terms, a boggy brain state. Content Type Journal ArticlePages 1-8DOI 10.1007/s12028-011-9543-6Authors Paul T. Akins, Department of Neurosurgery, Kaiser Sacramento Medical Center, Permanente Medical Group, 2025 Morse Avenue, Sacramento, CA 95825, USAKern H. Guppy, Department of Neurosurgery, Kaiser Sacramento Medical Center, Permanente Medical Group, 2025 Morse A... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4784142 Wed, 27 Apr 2011 05:47:43 +0100 4784142 http://www.medworm.com/index.php?rid=4784143&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fjt5612u300543761%2F Conclusions  Dietary therapy should be considered as a treatment option in adult patients with refractory status epilepticus. Content Type Journal ArticlePages 1-6DOI 10.1007/s12028-011-9546-3Authors Mackenzie C. Cervenka, Department of Neurology, Johns Hopkins University School of Medicine, 600 N. Wolfe St., Meyer 2-147, Baltimore, MD 21287-7247, USAAdam L. Hartman, Departments of Neurology and Pediatrics, Johns Hopkins University School of Medicine, 600 N. Wolfe St., Meyer 2-147, Baltimore, MD 21287-7247, USAArun Venkatesan, Departments of Neurology, Johns Hopkins University School of Medicine, 600 N. Wolfe St., Meyer 6-113, Baltimore, MD 21287-7247, USARomergryko G. Geocadin, Departments of Neurology, Neurosurgery and Anesthesiology-Critical Care Medicine, Johns Hopki... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4784143 Wed, 27 Apr 2011 05:47:42 +0100 4784143 http://www.medworm.com/index.php?rid=4784144&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fhh270025425446m5%2F Conclusions  Seizures were neither associated with a PbtO2 value of <20 mmHg nor associated with a drop in PbtO2 value across a clinically significant threshold. However, we cannot rule out the existence of any relationship between PbtO2 and seizure with this limited data set. Prospective research using electronically recorded data is required to more effectively examine the relationship between PbtO2 and seizure. Content Type Journal ArticlePages 1-8DOI 10.1007/s12028-011-9540-9Authors Soojin Park, Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, PA, USAAlexander Roederer, Department of Computer and Information Science, University of Pennsylvania School of Engineering and Applied Science, Philadelphia, PA, USARam Mani, Dep... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4784144 Wed, 27 Apr 2011 05:47:41 +0100 4784144 http://www.medworm.com/index.php?rid=4769030&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F85317gm52614h032%2F Abstract  Non-invasive measurement of intracranial pressure can be invaluable in the management of critically ill patients. We performed a comprehensive review of the literature to evaluate the different methods of measuring intracranial pressure. Several methods have been employed to estimate intracranial pressure, including computed tomography, magnetic resonance imaging, transcranial Doppler sonography, near-infrared spectroscopy, and visual-evoked potentials. In addition, multiple techniques of measuring the optic nerve and the optic nerve sheath diameter have been studied. Ultrasound measurements of the optic nerve sheath diameter and Doppler flow are especially promising and may be useful in selected settings. Content Type Journal ArticlePages 1-10DOI 10.1007/s120... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4769030 Tue, 26 Apr 2011 05:43:33 +0100 4769030 http://www.medworm.com/index.php?rid=4769032&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff3j6n4650m053544%2F Conclusions  Elevated intra-abdominal pressure can exacerbate intracranial hypertension in patients with TBI. Recognition of this condition and treatment with decompressive laparotomy may be useful in patients with intracranial hypertension refractory to optimal medical therapy. Content Type Journal ArticlePages 1-3DOI 10.1007/s12028-011-9549-0Authors Jon D. Dorfman, Department of Surgery, Boston University School of Medicine and Boston Medical Center, Boston, MA, USAJoseph D. Burns, Department of Neurology, Boston University School of Medicine and Boston Medical Center, 72 E. Concord St, Collamore Bldg C-3, Boston, MA 02119, USADeborah M. Green, Department of Neurology, Boston University School of Medicine and Boston Medical Center, 72 E. Concord St, Collamore Bldg ... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4769032 Tue, 26 Apr 2011 05:43:32 +0100 4769032 http://www.medworm.com/index.php?rid=4769031&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp2367x8818392624%2F Conclusions  Neurological patients cared for in specialty neuro-ICUs underwent more invasive intracranial and hemodynamic monitoring, tracheostomy, and nutritional support, and received less IV sedation than patients in general ICUs. These differences in care may explain previously observed disparities in outcome between neurocritical care and general ICUs. Content Type Journal ArticlePages 1-4DOI 10.1007/s12028-011-9539-2Authors Pedro Kurtz, The Departments of Neurology and Neurosurgery, Columbia University, New York, NY, USAVincent Fitts, The Greater New York Hospital Association (GNYHA) and United Hospital Fund (UHF), New York, NY, USAZeynep Sumer, The Greater New York Hospital Association (GNYHA) and United Hospital Fund (UHF), New York, NY, USAHillary Jalon, The... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4769031 Tue, 26 Apr 2011 05:43:32 +0100 4769031 http://www.medworm.com/index.php?rid=4749665&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Flw5w55u473973263%2F Conclusions  With both acidic drugs present, a loading dose of valproic acid may displace warfarin from the protein binding sites resulting in redistribution of warfarin in free active form and lead to a rapid increase in INR. Content Type Journal ArticlePages 1-4DOI 10.1007/s12028-011-9544-5Authors Hyue W. Yoon, Pharmacy Services (HWY), Division of Critical Care Neurology (EFMW and EAG), Mayo Clinic, Rochester, MN 55905, USAElias A. Giraldo, Pharmacy Services (HWY), Division of Critical Care Neurology (EFMW and EAG), Mayo Clinic, Rochester, MN 55905, USAEelco F. M. Wijdicks, Pharmacy Services (HWY), Division of Critical Care Neurology (EFMW and EAG), Mayo Clinic, Rochester, MN 55905, USA Journal Neurocritical CareOnline ISSN 1556-0961Print ISSN 1541-6933 (Sour... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4749665 Fri, 22 Apr 2011 05:45:52 +0100 4749665 http://www.medworm.com/index.php?rid=4745415&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw033125l051316w2%2F Conclusion  The combination of IBU and APAP produces significantly greater fever control than APAP alone, with trends favoring the combination over IBU alone and IBU over APAP alone. Content Type Journal ArticlePages 1-4DOI 10.1007/s12028-011-9533-8Authors Michael E. Mullins, Washington University, St. Louis, MO, USAMatthew Empey, Washington University, St. Louis, MO, USADavid Jaramillo, Washington University, St. Louis, MO, USASameta Sosa, Washington University, St. Louis, MO, USATheresa Human, Washington University, St. Louis, MO, USAMichael N. Diringer, Washington University, St. Louis, MO, USA Journal Neurocritical CareOnline ISSN 1556-0961Print ISSN 1541-6933 (Source: Neurocritical Care) Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4745415 Tue, 19 Apr 2011 06:49:45 +0100 4745415 http://www.medworm.com/index.php?rid=4745416&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fdm83wx6112581t05%2F Conclusion  Our pilot study suggests that RYRs are involved in the complex pathophysiology of vasospasm development following SAH. The potential role of RYR1 as a biomarker for prediction of cerebral vasospasm after SAH has to be confirmed in a larger clinical trial. Content Type Journal ArticlePages 1-6DOI 10.1007/s12028-011-9542-7Authors Henrik Rueffert, Department of Anaesthesiology and Intensive Care Medicine, HELIOS Kliniken, Rudolf Virchow Str. 2, 04552 Borna, GermanyAnja Gumplinger, Department of Anaesthesiology and Intensive Care Medicine, Medical Faculty, University of Leipzig, Leipzig, GermanyChristof Renner, Department of Neurosurgery, University of Leipzig, Medical Faculty, Leipzig, GermanyMarkus Dengl, Department of Neurosurgery, University of Leipzig, M... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4745416 Tue, 19 Apr 2011 06:49:40 +0100 4745416 http://www.medworm.com/index.php?rid=4706072&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F38u678p063wv0336%2F Conclusions  Elevated levels of BNP are strongly and independently associated with cerebral infarction, and the association is most pronounced in patients without angiographic vasospasm. These results provide further evidence that other mechanisms can contribute to infarction, and BNP may be a useful biomarker in detecting patients at risk for adverse outcomes without large vessel vasospasm. Content Type Journal ArticlePages 1-6DOI 10.1007/s12028-011-9535-6Authors Pam R. Taub, Department of Medicine, Cardiology Division, University of California, San Diego, CA, USAJeremy D. Fields, Departments of Neurology and Interventional Neuroradiology, Oregon Health & Science University, Portland, OR, USAAlan H. B. Wu, Department of Laboratory Medicine, University of California,... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4706072 Fri, 08 Apr 2011 16:57:34 +0100 4706072 http://www.medworm.com/index.php?rid=4688230&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw227r64n131831r7%2F Conclusions  SDD in mechanically ventilated GBS patients reduced the time on the ventilator, probably by preventing VAP, but did not affect neurological recovery after 6 months. Content Type Journal ArticlePages 1-6DOI 10.1007/s12028-011-9536-5Authors Martine E. Bos Eyssen, Department of Neurology, Erasmus MC-University Medical Center, Rotterdam, The NetherlandsPieter A. van Doorn, Department of Neurology, Erasmus MC-University Medical Center, Rotterdam, The NetherlandsBart C. Jacobs, Department of Neurology, Erasmus MC-University Medical Center, Rotterdam, The NetherlandsEwout W. Steyerberg, Department of Public Health, Erasmus MC-University Medical Center, Rotterdam, The NetherlandsPeter H. J. van der Voort, Department of Intensive Care, Onze Lieve Vrouwe Gasth... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4688230 Wed, 06 Apr 2011 06:46:38 +0100 4688230 http://www.medworm.com/index.php?rid=4688231&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd2x7x4p830101637%2F Conclusions  Intra-arterial nicardipine is associated with significant intra-operative blood pressure lowering, an increased requirement for intra-operative vasopressor therapy, and a tendency toward re-treatment when used as initial monotherapy for vasospasm. Content Type Journal ArticlePages 1-5DOI 10.1007/s12028-011-9537-4Authors Neil Rosenberg, Department of Neurological Sciences, Rush University Medical Center, 1725 W. Harrison St., Suite 1121, Chicago, IL 60612, USAMarc A. Lazzaro, Department of Neurological Sciences, Rush University Medical Center, 1725 W. Harrison St., Suite 1121, Chicago, IL 60612, USADemetrius K. Lopes, Department of Neurosurgery, Rush University Medical Center, Chicago, IL, USAShyam Prabhakaran, Department of Neurological Sciences, Rush U... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4688231 Wed, 06 Apr 2011 06:46:37 +0100 4688231 http://www.medworm.com/index.php?rid=4688232&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff32kv018243570u7%2F Conclusions  Frequent and early surveillance imaging should be obtained in patients with H1N1 influenza infection undergoing ECMO, although the presence of diffuse cerebral injury, including intraparenchymal hemorrhage and multifocal punctate susceptibility effect, does not necessarily portend a poor prognosis. Content Type Journal ArticlePages 1-5DOI 10.1007/s12028-011-9534-7Authors Felicia C. Chow, Department of Neurology, Massachusetts General Hospital, 15 Parkman Street, Wang Ambulatory Care Center, Suite 835, Boston, MA 02114, USABrian L. Edlow, Department of Neurology, Massachusetts General Hospital, 15 Parkman Street, Wang Ambulatory Care Center, Suite 835, Boston, MA 02114, USAMatthew P. Frosch, C.S. Kubik Laboratory for Neuropathology, Massachusetts General ... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4688232 Tue, 05 Apr 2011 10:01:55 +0100 4688232 http://www.medworm.com/index.php?rid=4646220&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F99766g470235645j%2F Conclusions  The use of endovascular cooling in the management of severe life threatening hyperthermia in patients with cervical SCI may be an useful intervention. There must be a high suspicion for the possibility of deep vein thrombosis in this subgroup, however. Content Type Journal ArticlePages 1-4DOI 10.1007/s12028-011-9529-4Authors Swagata Tripathy, Department of Neuroanaesthesia and Neurointensive Care, The Walton Centre of Neurosciences, Liverpool, UKChristopher F. Whitehead, Department of Neuroanaesthesia and Neurointensive Care, The Walton Centre of Neurosciences, Liverpool, UK Journal Neurocritical CareOnline ISSN 1556-0961Print ISSN 1541-6933 (Source: Neurocritical Care) Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4646220 Sun, 27 Mar 2011 05:47:20 +0100 4646220 http://www.medworm.com/index.php?rid=4628357&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F488x2mm0576512r8%2F Conclusion  The implementation of a neurointensivist-led neurocritical care team is associated with improved hospital discharge disposition for patients with aneurysmal subarachnoid hemorrhage. Content Type Journal ArticlePages 1-7DOI 10.1007/s12028-011-9505-zAuthors Owen Samuels, Department of Neurosurgery, Emory University School of Medicine, 1365 Clifton Road NE, Atlanta, GA 30322, USAAdam Webb, Department of Neurosurgery, Emory University School of Medicine, 1365 Clifton Road NE, Atlanta, GA 30322, USASteve Culler, Rollins School of Public Health, Emory University, Atlanta, GA USAKathleen Martin, Department of Neurosurgery, Emory University School of Medicine, 1365 Clifton Road NE, Atlanta, GA 30322, USADaniel Barrow, Department of Neurosurgery, Emory University S... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4628357 Tue, 22 Mar 2011 06:04:36 +0100 4628357 http://www.medworm.com/index.php?rid=4617888&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb83g85316v700pph%2F Content Type Journal ArticlePages 1-5DOI 10.1007/s12028-011-9530-yAuthors Andreas H. Kramer, Departments of Critical Care Medicine & Clinical Neurosciences, Hotchkiss Brain Institute, Foothills Medical Center, University of Calgary, Calgary, CanadaDavid A. Zygun, Departments of Critical Care Medicine, Clinical Neurosciences & Community Health Sciences, Hotchkiss Brain Institute, Foothills Medical Center, University of Calgary, Calgary, Canada Journal Neurocritical CareOnline ISSN 1556-0961Print ISSN 1541-6933 (Source: Neurocritical Care) Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4617888 Fri, 18 Mar 2011 16:47:23 +0100 4617888 http://www.medworm.com/index.php?rid=4617889&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb084t6lw85153622%2F Conclusions  There is currently inadequate data to support the application of PbtO2 monitoring in children with stroke to prevent progressive ischemia and to improve outcome. However, the positive results for these two patients support the need for further study in this area. Content Type Journal ArticlePages 1-8DOI 10.1007/s12028-011-9531-xAuthors Baxter B. Allen, Division of Child Neurology, Department of Pediatrics, Weill Cornell Medical College, New York, USACaitlin E. Hoffman, Department of Neurological Surgery, New York Presbyterian Hospital, Weill Cornell Medical College, 525 East 68th St, P. O. Box 99, New York, NY 10065, USAChani S. Traube, Division of Critical Care, Department of Pediatrics, Weill Cornell Medical College, New York, USASteven L. Weinstein, Di... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4617889 Thu, 17 Mar 2011 18:31:15 +0100 4617889 http://www.medworm.com/index.php?rid=4607505&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx11p210657222460%2F Conclusions  These data suggest that a single dose conivaptan is safe in non-hyponatremic patients with severe TBI and may reduce ICP. Further studies are needed to establish the effect of conivaptan on clinically relevant endpoints, and its role in the management of intracranial hypertension. Content Type Journal ArticlePages 1-7DOI 10.1007/s12028-011-9525-8Authors Christopher Galton, School of Medicine, University of Colorado Denver, Aurora, CO USASteven Deem, Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA USAN. David Yanez, Department of Biostatistics, University of Washington, Seattle, WA USAMichael Souter, Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, WA USARandall Chesnut, Department of... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4607505 Wed, 16 Mar 2011 12:02:28 +0100 4607505 http://www.medworm.com/index.php?rid=4607506&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm3584q4u51585870%2F Conclusions  Type of acid suppression therapy was not associated with DNDs or delayed infarction following aneurysmal SAH. However, PPI use was associated with poorer functional outcome. Further study of acid suppression therapy and PPI use following SAH is warranted. Content Type Journal ArticlePages 1-7DOI 10.1007/s12028-011-9532-9Authors Jeffrey J. Fletcher, Department of Neurosurgery, University of Michigan Health System, 3552 Taubman Health Care Center, 1500 E. Medical Center Drive, Ann Arbor, MI 48109-5338, USADevin L. Brown, Department of Neurology, University of Michigan Health System, 1500 E. Medical Center Drive, Ann Arbor, MI 48109-5855, USAVenkatakrishna Rajajee, Department of Neurosurgery, University of Michigan Health System, 3552 Taubman Health Care Ce... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4607506 Wed, 16 Mar 2011 12:02:24 +0100 4607506 http://www.medworm.com/index.php?rid=4607507&cid=s_36002_25_f&fid=36002&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fvh0865594j511m31%2F Conclusions  SAH patients with NC tend to have greater CSF catecholamine levels than those without NC. However, the development of NC may also be related to factors not evaluated by our study. Content Type Journal ArticlePages 1-6DOI 10.1007/s12028-011-9527-6Authors Michael Moussouttas, Cerebrovascular and Neurocritical Care Division, Thomas Jefferson Medical Center, 900 Walnut Street, Suite 200, Philadelphia, PA 19107, USAEdwin W. Lai, Section on Medical Neuroendocrinology, Reproductive and Adult Endocrinology Program, National Institutes of Health, Bethesda, MD USAKeith Dombrowski, Department of Neurology, Thomas Jefferson Medical Center, Philadelphia, PA USAThanh T. Huynh, Section on Medical Neuroendocrinology, Reproductive and Adult Endocrinology Program, National... Neurocritical Care journals http://www.medworm.com/rss/comments.php?id=4607507 Wed, 16 Mar 2011 12:02:22 +0100 4607507