MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Nonlinear Biomedical Physics' source. Sun, 21 Mar 2010 17:14:54 +0100 http://www.medworm.com/index.php?rid=3377870&cid=s_37188_75_f&fid=37188&url=http%3A%2F%2Fwww.nonlinearbiomedphys.com%2Fcontent%2F4%2F1%2F1 In this paper we present a fractional order generalization of Perelson et al. basic hepatitis C virus (HCV) model including an immune response term. We argue that fractional order equations are more suitable than integer order ones in modeling complex systems which include biological systems. The model is presented and discussed. Also we argue that the added immune response term represents some basic properties of the immune system and that it should be included to study longer term behavior of the disease. (Source: Nonlinear Biomedical Physics) Nonlinear Biomedical Physics journals http://www.medworm.com/rss/comments.php?id=3377870 Thu, 18 Mar 2010 00:00:00 +0100 3377870 http://www.medworm.com/index.php?rid=2886091&cid=s_37188_75_f&fid=37188&url=http%3A%2F%2Fwww.nonlinearbiomedphys.com%2Fcontent%2F3%2F1%2F11 Many attempts to control Complex adaptive systems (CAS) have failed. Here we try to learn from biosystems to derive some principles for CAS management. An application to managing infections is given. (Source: Nonlinear Biomedical Physics) Nonlinear Biomedical Physics journals http://www.medworm.com/rss/comments.php?id=2886091 Sun, 11 Oct 2009 23:00:00 +0100 2886091 http://www.medworm.com/index.php?rid=2765485&cid=s_37188_75_f&fid=37188&url=http%3A%2F%2Fwww.nonlinearbiomedphys.com%2Fcontent%2F3%2F1%2F10 Laccase, an enzyme responsible for aerobic transformations of natural phenolics, in industrial applications requires the presence of low-molecular substances known as mediators, which accelerate oxidation processes. However, the use of mediators is limited by their toxicity and the high costs of exploitation. The activation of extracellular laccase in growing fungal culture with highly diluted mediators, ABTS and HBT is described. Two high laccase-producing fungal strains, Trametes versicolor and Cerrena unicolor, were used in this study as a source of enzyme. Selected dilutions of the mediators significantly increased the activity of extracellular laccase during 14 days of cultivation what was distinctly visible in PAGE technique and in colorimetric tests. The same mediator dilutions incr... Nonlinear Biomedical Physics journals http://www.medworm.com/rss/comments.php?id=2765485 Thu, 03 Sep 2009 23:00:00 +0100 2765485 http://www.medworm.com/index.php?rid=2724358&cid=s_37188_75_f&fid=37188&url=http%3A%2F%2Fwww.nonlinearbiomedphys.com%2Fcontent%2F3%2F1%2F9 Conclusion: LGG patients display higher short- and long-distance synchronization within the theta band. Network analysis revealed changes (in particularly the theta, beta, and upper gamma band) suggesting disturbed network architecture. Moreover, correlations between network characteristics and neurocognitive performance were found, Widespread changes in the strength and spatial organization of brain networks may be responsible for cognitive dysfunction in glioma patients. (Source: Nonlinear Biomedical Physics) Nonlinear Biomedical Physics journals http://www.medworm.com/rss/comments.php?id=2724358 Sat, 22 Aug 2009 23:00:00 +0100 2724358 http://www.medworm.com/index.php?rid=2637538&cid=s_37188_75_f&fid=37188&url=http%3A%2F%2Fwww.nonlinearbiomedphys.com%2Fcontent%2F3%2F1%2F7 Conclusions: This simulation study, though focused on a simple effect attaining TPR modulation due to pulsatility, suggests that non-linear autoregulation mechanisms cannot be overlooked in the analysis of the integrated behavior of the global cardiovascular system, including the arterial tree and the peripheral vascular bed. (Source: Nonlinear Biomedical Physics) Nonlinear Biomedical Physics journals http://www.medworm.com/rss/comments.php?id=2637538 Thu, 23 Jul 2009 23:00:00 +0100 2637538 http://www.medworm.com/index.php?rid=2911914&cid=s_37188_75_f&fid=37188&url=http%3A%2F%2Fwww.nonlinearbiomedphys.com%2Fcontent%2F3%2F1%2F6 Conclusion: In this article, differences in characteristics for normal subjects with eyes open and closed, epileptic subjects during seizure and seizure free intervals have been shown mainly using Hurst exponent. The H shows that the brain activity of a normal man is uncorrelated in nature whereas, epileptic brain activity shows long range anticorrelation. (Source: Nonlinear Biomedical Physics) Nonlinear Biomedical Physics journals http://www.medworm.com/rss/comments.php?id=2911914 Sun, 19 Jul 2009 23:00:00 +0100 2911914 http://www.medworm.com/index.php?rid=2616569&cid=s_37188_75_f&fid=37188&url=http%3A%2F%2Fwww.nonlinearbiomedphys.com%2Fcontent%2F3%2F1%2F6 Conclusions: In this article, differences in characteristics for normal subjects with eyes open and closed, epileptic subjects during seizure and seizure free intervals have been shown mainly using Hurst exponent. The H shows that the brain activity of a normal man is uncorrelated in nature whereas, epileptic brain activity shows long range anticorrelation. (Source: Nonlinear Biomedical Physics) Nonlinear Biomedical Physics journals http://www.medworm.com/rss/comments.php?id=2616569 Sun, 19 Jul 2009 23:00:00 +0100 2616569 http://www.medworm.com/index.php?rid=2587798&cid=s_37188_75_f&fid=37188&url=http%3A%2F%2Fwww.nonlinearbiomedphys.com%2Fcontent%2F3%2F1%2F4 Conclusions: These results suggest that critical propagation of excitation waves determines conditions for transition to unstable rhythms in a way similar to unstable cardiac rhythms. Established conditions were suitably accurate regardless of rate dependent features and the magnitude of the slopes of restitution curves. (Source: Nonlinear Biomedical Physics) Nonlinear Biomedical Physics journals http://www.medworm.com/rss/comments.php?id=2587798 Wed, 08 Jul 2009 23:00:00 +0100 2587798 http://www.medworm.com/index.php?rid=2505605&cid=s_37188_75_f&fid=37188&url=http%3A%2F%2Fwww.nonlinearbiomedphys.com%2Fcontent%2F3%2F1%2F3 It is argued that by studying some design principles of the immune system ,e.g. nonlinearity and being a complex adaptive system, one can easily find some explanations of basic properties of the system e.g. memory and tolerance. (Source: Nonlinear Biomedical Physics) Nonlinear Biomedical Physics journals http://www.medworm.com/rss/comments.php?id=2505605 Wed, 10 Jun 2009 23:00:00 +0100 2505605 http://www.medworm.com/index.php?rid=2436431&cid=s_37188_75_f&fid=37188&url=http%3A%2F%2Fwww.nonlinearbiomedphys.com%2Fcontent%2F3%2F1%2F2 We answer several important questions concerning EEG. We also shortly discuss importance of nonlinear methods of contemporary physics in EEG analysis. Basic definitions and explanation of fundamental concepts may be found in my previous publications in NBP. (Source: Nonlinear Biomedical Physics) Nonlinear Biomedical Physics journals http://www.medworm.com/rss/comments.php?id=2436431 Tue, 26 May 2009 04:00:00 +0100 2436431 http://www.medworm.com/index.php?rid=2151047&cid=s_37188_75_f&fid=37188&url=http%3A%2F%2Fwww.nonlinearbiomedphys.com%2Fcontent%2F3%2F1%2F1 Conclusions: Support to absence ratio of Hilbert-Huang Transformation on mismatch negativity meets the theoretical expectations, i.e., larger deviant elicits larger MMN. However, Morlet wavelet transformation does not. Thus, HHT seems more appropriate in analyzing event-related potentials in the time-frequency domain. HHT appears to evaluate ERPs more accurately and provide theoretically valid information of the brain responses. (Source: Nonlinear Biomedical Physics) Nonlinear Biomedical Physics journals http://www.medworm.com/rss/comments.php?id=2151047 Mon, 02 Feb 2009 05:00:00 +0100 2151047 http://www.medworm.com/index.php?rid=1556936&cid=s_37188_75_f&fid=37188&url=http%3A%2F%2Fwww.nonlinearbiomedphys.com%2Fcontent%2F2%2F1%2F2 In the study of epidemic spreading two natural questions are: whether the spreading of epidemics on heterogenous networks have multiple routes, and whether the spreading of an epidemic is a local or global behavior? In this paper, we answer the above two questions by studying the SIS model on heterogenous networks, and give the global conditions for the endemic state when two distinct routes with uniform rate of infection are considered. The analytical results are also verified by numerical simulations. (Source: Nonlinear Biomedical Physics) Nonlinear Biomedical Physics journals http://www.medworm.com/rss/comments.php?id=1556936 Thu, 01 May 2008 04:00:00 +0100 1556936 http://www.medworm.com/index.php?rid=1556937&cid=s_37188_75_f&fid=37188&url=http%3A%2F%2Fwww.nonlinearbiomedphys.com%2Fcontent%2F2%2F1%2F1 Conclusions: Monitoring of heart movements and pulse wave propagation may be used e.g. to estimate the aortic pulse wave velocity, which is widely accepted as an index of aortic stiffness with the application of predicting risk of heart disease in individuals. More extended analysis of the method is however needed to assess its possible clinical application. (Source: Nonlinear Biomedical Physics) Nonlinear Biomedical Physics journals http://www.medworm.com/rss/comments.php?id=1556937 Fri, 22 Feb 2008 05:00:00 +0100 1556937 http://www.medworm.com/index.php?rid=1556939&cid=s_37188_75_f&fid=37188&url=http%3A%2F%2Fwww.nonlinearbiomedphys.com%2Fcontent%2F1%2F1%2F10 Variability in cell properties can be an important driving mechanism behind spatiotemporal patterns in biological systems, as the degree of cell-to-cell differences determines the capacity of cells to locally synchronize and, consequently, form patterns on a larger spatial scale. In principle, certain features of spatial patterns emerging with time may be regulated by variability or, more specifically, by certain constellations of cell-to-cell differences. Similarly, measuring variability in a system (i.e. the spatial distribution of cell-cell differences) may help predict properties of later-stage patterns.Here we apply and compare different statistical methods of extracting such systematic cell-to-cell differences in the case of patterns generated with a simple model system of an excitab... Nonlinear Biomedical Physics journals http://www.medworm.com/rss/comments.php?id=1556939 Thu, 30 Aug 2007 04:00:00 +0100 1556939 http://www.medworm.com/index.php?rid=1556938&cid=s_37188_75_f&fid=37188&url=http%3A%2F%2Fwww.nonlinearbiomedphys.com%2Fcontent%2F1%2F1%2F11 Drugs designed for a specific target are always found to have multiple effects. Rather than hope that one bullet can be designed to hit only one target, nonlinear interactions across genomic and proteomic networks could be used to design Combinatorial Multi-Component Therapies (CMCT) that are more targeted with fewer side effects. We show here how computational approaches can be used to predict which combinations of drugs would produce the best effects. Using a nonlinear model of how the output effect depends on multiple input drugs, we show that an artificial neural network can accurately predict the effect of all 215 = 32,768 combinations of drug inputs using only the limited data of the output effect of the drugs presented one-at-a-time and pairs-at-a-time. (Source: Nonlinear Biomedical... Nonlinear Biomedical Physics journals http://www.medworm.com/rss/comments.php?id=1556938 Thu, 30 Aug 2007 04:00:00 +0100 1556938 http://www.medworm.com/index.php?rid=1556940&cid=s_37188_75_f&fid=37188&url=http%3A%2F%2Fwww.nonlinearbiomedphys.com%2Fcontent%2F1%2F1%2F7 This study utilises the RRM computational approach to the analysis of oncogene and proto-oncogene proteins. The results obtained have shown that the RRM is capable of identifying the differences between the oncogenic and proto-oncogenic proteins with the possibility of identifying the "cancer-causing" features within their protein primary structure. In addition, the rational design of bioactive peptide analogues displaying oncogenic or proto-oncogenic-like activity is presented here. (Source: Nonlinear Biomedical Physics) Nonlinear Biomedical Physics journals http://www.medworm.com/rss/comments.php?id=1556940 Thu, 19 Jul 2007 04:00:00 +0100 1556940 http://www.medworm.com/index.php?rid=1556941&cid=s_37188_75_f&fid=37188&url=http%3A%2F%2Fwww.nonlinearbiomedphys.com%2Fcontent%2F1%2F1%2F6 Conclusion: The CPAP efficacy depends on the level of OLDMO. CPAP is efficient in the severe OLDMO because it increases the optimal BF, which makes possible less energy-consuming breathing with frequency close to the normal one (greater BF means smaller tidal volume and thus smaller work against lungs compliance). (Source: Nonlinear Biomedical Physics) Nonlinear Biomedical Physics journals http://www.medworm.com/rss/comments.php?id=1556941 Mon, 16 Jul 2007 04:00:00 +0100 1556941 http://www.medworm.com/index.php?rid=1556942&cid=s_37188_75_f&fid=37188&url=http%3A%2F%2Fwww.nonlinearbiomedphys.com%2Fcontent%2F1%2F1%2F5 Methods of contemporary physics are increasingly important for biomedical research but, for a multitude of diverse reasons, most practitioners of biomedicine lack access to a comprehensive knowledge of these modern methodologies. This paper is an attempt to describe nonlinear dynamics and its methods in a way that could be read and understood by biomedical professionals who usually are not trained in advanced mathematics. After an overview of basic concepts and vocabulary of nonlinear dynamics, deterministic chaos, and fractals, application of nonlinear methods of biosignal analysis is discussed. In particular, five case studies are presented: 1. Monitoring the depth of anaesthesia and of sedation; 2. Bright Light Therapy and Seasonal Affective Disorder; 3. Analysis of posturographic sign... Nonlinear Biomedical Physics journals http://www.medworm.com/rss/comments.php?id=1556942 Thu, 05 Jul 2007 04:00:00 +0100 1556942