MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Ophthalmology' source. Wed, 08 Feb 2012 23:31:44 +0100 http://www.medworm.com/index.php?rid=5650897&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011010815%2Fabstract%3Frss%3Dyes We would like to congratulate Dr. Bastawrous on his innovative and well-documented technique of “Smartphone Fundoscopy.” We agree with him that our method of viewing the fundus with the smartphone, 20 diopter lens and flash light is not as easy as his technique using the flash light feature of the newly available smartphones. We would like to clarify that when we wrote our article, we were not aware of a smartphone with a flashlight that was commonly available. However, with the availability of this new feature, flashlight technology and higher-resolution camera fundus documentation with the smartphones has become easier. This technique may lead to more widespread use of this modality for fundus documentation. As Dr. Bastawrous mentioned, with this technique it is very important to be ... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650897 Wed, 01 Feb 2012 05:00:00 +0100 5650897 http://www.medworm.com/index.php?rid=5650896&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011010827%2Fabstract%3Frss%3Dyes More ophthalmologists than ever carry a smartphone with them on a daily basis. There are many ophthalmic applications (apps) and reference texts available on a variety of platforms. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650896 Wed, 01 Feb 2012 05:00:00 +0100 5650896 http://www.medworm.com/index.php?rid=5650895&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011010888%2Fabstract%3Frss%3Dyes We have carefully reviewed the commentary by Drs. Blair and Shapiro regarding the need for a change in retinopathy of prematurity (ROP) screening behavior both with respect to its duration and frequency following off-label administration of bevacizumab for zone I, stage 3+ ROP as advocated by the BEAT-ROP Study Group, and note that it highlights our own specific concerns outlined in our editorial. Specifically, we wrote, “Treatment with bevacizumab is not a one-and-done therapy.” (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650895 Wed, 01 Feb 2012 05:00:00 +0100 5650895 http://www.medworm.com/index.php?rid=5650894&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS016164201101089X%2Fabstract%3Frss%3Dyes We read with interest the editorial by Moshfeghi and Berrocal regarding the Bevacizumab Eliminates the Angiogenic Threat of Retinopathy of Prematurity (BEAT-ROP) study which reported the first randomized trial of anti-vascular endothelial growth factor (VEGF) treatment for ROP. The BEAT-ROP study reported a statistically significant reduction, by 54 weeks postmenstrual age (PMA), in treatment requiring recurrence of ROP in eyes treated with bevacizumab injection as compared with laser ablation. In their editorial, Moshfeghi and Berrocal note the eyes in the bevacizumab group had later mean onset of recurrence with large standard deviation and state concern for recurrence after the 54-week study endpoint. For zone 1 disease, this interval was 6.4±6.7 weeks after laser treatment but 19.2±8... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650894 Wed, 01 Feb 2012 05:00:00 +0100 5650894 http://www.medworm.com/index.php?rid=5650893&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011008463%2Fabstract%3Frss%3Dyes We would like to thank Dr. Park et al for their interest and their comments on our article, “High-resolution imaging of photoreceptor layer in epiretinal membrane using adaptive optics scanning laser ophthalmoscopy.” (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650893 Wed, 01 Feb 2012 05:00:00 +0100 5650893 http://www.medworm.com/index.php?rid=5650892&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011008475%2Fabstract%3Frss%3Dyes We read with interest the recent article by Ooto et al entitled, “High-resolution imaging of photoreceptor layer in epiretinal membrane using adaptive optics scanning laser ophthalmoscopy,” published in May 2011. The article describes foveal microfolds in eyes with epiretinal membrane and metamorphopsia visualized using adaptive optics scanning laser ophthalmoscopy (AO-SLO), a finding not noted in normal eyes. They describe this finding as an “abnormality…not reported in previous studies of normal eyes or eyes with various other retinal diseases examined by AO imaging systems.” (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650892 Wed, 01 Feb 2012 05:00:00 +0100 5650892 http://www.medworm.com/index.php?rid=5650891&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011009936%2Fabstract%3Frss%3Dyes We thank Chatterjee et al for their observations regarding the role of confocal microscopy in the diagnosis of infective keratitis. We would like to reiterate that our study was designed as a double-masked protocol with confocal microscopy performed first followed by microbiology evaluation, with both the evaluator studying the confocal scans and the microbiologist processing the slides and cultures masked to the results of the other's results. Only following the completion of the study and tabulation of the results, did the false positives and negatives emerge. Since the primary purpose of the study was to evaluate the sensitivity and specificity of the confocal microscope in diagnosing fungal and Acanthamoeba keratitis, we did not reexamine the scans from the false positives and false-n... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650891 Wed, 01 Feb 2012 05:00:00 +0100 5650891 http://www.medworm.com/index.php?rid=5650890&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011009924%2Fabstract%3Frss%3Dyes We have read with interest the article by Vaddavalli et al on the role of confocal microscopy in the diagnosis of infectious keratitis due to fungi and acanthamoeba. The authors found that about 10% of fungal keratitis could not be diagnosed with confocal microscopy, but do not suggest reasons for this. A possible explanation for false-negative results has been provided in another series published after Vaddavalli's article had been submitted, where it was suggested that hazy images and lack of patient cooperation may be possible causes of not detecting fungal filaments. Were the scans in this false-negative group of patients in the present study re-examined after microbiological confirmation to detect filaments that may have been missed or were additional scans performed? This might not ... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650890 Wed, 01 Feb 2012 05:00:00 +0100 5650890 http://www.medworm.com/index.php?rid=5650889&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011010414%2Fabstract%3Frss%3Dyes We would like to thank Dr. Yip and Dr. Sparrow for their thoughtful comments on our paper entitled, “A Critical Appraisal and Comparison of the Quality and Recommendations of Glaucoma Practice Guidelines.” (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650889 Wed, 01 Feb 2012 05:00:00 +0100 5650889 http://www.medworm.com/index.php?rid=5650888&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011010402%2Fabstract%3Frss%3Dyes We read with interest the article by Ou et al article appraising 3 primary open angle glaucoma (POAG) clinical practice guidelines. Evaluation using the Appraisal of Guidelines for Research and Evaluation (AGREE) instrument showed poor scores in the domains of stakeholder involvement, applicability, and editorial independence. Good clinical guidelines aim to improve the quality of healthcare, with the potential to change the process of health care and improve clinical outcomes. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650888 Wed, 01 Feb 2012 05:00:00 +0100 5650888 http://www.medworm.com/index.php?rid=5650887&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011009882%2Fabstract%3Frss%3Dyes We would like to begin by thanking Zabalza et al for their thoughtful questions and comments. In our article, we describe complication rates by year of residency. We certainly think that correlating complications with surgical experience on a resident-by-resident basis is an interesting topic, however, we feel it is a separate question. We are not seeking to elucidate the mechanisms of the resident learning curve for phacoemulsification. Rather, we are trying to draw conclusions about the overall complication rate for residents of a particular level. Since residents have varying levels of exposure to particular surgeries and natural ability (and since we as teachers can control neither), studies are needed that examine the issue in aggregate in order to inform teaching policy. The concern ... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650887 Wed, 01 Feb 2012 05:00:00 +0100 5650887 http://www.medworm.com/index.php?rid=5650886&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011009894%2Fabstract%3Frss%3Dyes We are writing regarding the recent report by Woodfield et al about resident cataract surgery complication rates. We definitely agree that it provides useful information that we might apply to our Ophthalmology Residency Training Program. However, it is also true that the results provided in this article are rather controversial. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650886 Wed, 01 Feb 2012 05:00:00 +0100 5650886 http://www.medworm.com/index.php?rid=5650885&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011008888%2Fabstract%3Frss%3Dyes The ophthalmology residency matching has been used in the United States for over 30 years. Each institution reviews applications, and selected applicants are invited for Face-to-Face Interviews (FFIs). However, total interviewing expenses can be costly for applicants, and interview schedules among different institutions may conflict. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650885 Wed, 01 Feb 2012 05:00:00 +0100 5650885 http://www.medworm.com/index.php?rid=5650884&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS016164201100933X%2Fabstract%3Frss%3Dyes We report the clinical features and management in 6 cases of SMG orbital abscess. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650884 Wed, 01 Feb 2012 05:00:00 +0100 5650884 http://www.medworm.com/index.php?rid=5650883&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011010876%2Fabstract%3Frss%3Dyes We describe a young, otherwise healthy Australian woman with unilateral metastatic panophthalmitis and blindness associated with congenital cardiac anomalies. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650883 Wed, 01 Feb 2012 05:00:00 +0100 5650883 http://www.medworm.com/index.php?rid=5650882&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011008931%2Fabstract%3Frss%3Dyes Although many studies have demonstrated that the AcrySof ReSTOR SN6AD1 intraocular lenses (IOLs) with a near add of +3.00 diopter (D) can yield a full range of visual outcomes, especially intermediate visual outcomes, it is still of interest to evaluate visual function and possible adverse effects of the +3D IOL. Thus, we sought to investigate the optical quality of eyes implanted with the +3D IOL compared with a standard aspheric monofocal IOL, and analyzed specific indicators of optical quality—intraocular straylight, wavefront aberration, and contrast sensitivity (CS). (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650882 Wed, 01 Feb 2012 05:00:00 +0100 5650882 http://www.medworm.com/index.php?rid=5650849&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011011389%2Fabstract%3Frss%3Dyes With apologies from the publisher, in the Letter to the Editor entitled, “Transmittance Curve of an IOL” (Ophthalmology 2011;118:2309), the authors' names should have appeared as follows: Christophe Pagnoulle, PhD, Dimitriya Bozukova, PhD, Laure Gobin, PhD. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650849 Wed, 01 Feb 2012 05:00:00 +0100 5650849 http://www.medworm.com/index.php?rid=5650847&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011008359%2Fabstract%3Frss%3Dyes The frequency of musculoskeletal disorders (MSD) has been reported in the ophthalmic literature over the last decade. Based upon different criteria, survey instruments, and populations studied, the prevalence of MSD symptoms in ophthalmologists varies. Kitzmann et al report the first study that compares MSD symptoms in ophthalmologists to family medicine doctors at 2 institutions using the same survey instrument. Ophthalmologists reported a statistically significant increased prevalence of neck, hand/wrist, and lower back pain in comparison to their family medicine doctor colleagues. Although the number of ophthalmologists surveyed was relatively low, and findings in practice settings as opposed to these 2 academic institutions may differ, the rates of symptoms among ophthalmologists were ... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650847 Wed, 01 Feb 2012 05:00:00 +0100 5650847 http://www.medworm.com/index.php?rid=5650846&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011012036%2Fabstract%3Frss%3Dyes (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650846 Wed, 01 Feb 2012 05:00:00 +0100 5650846 http://www.medworm.com/index.php?rid=5650845&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642012000024%2Fabstract%3Frss%3Dyes 活体共焦显微镜 (IVCM) 有助于我们了解翿年人透明角膜的 形态多样性. Hillenaar et al (p. 241) 等确认正常角膜翿年性 特征性改变: 基质微粒, 后基质皱褶, Descemet 膜混浊和角膜 小滴. 这项横断面观察研究包括 75 例健康男性和 75 例健康 女性的 300 只眼. 此外, 作者还发现了一些和年龄不相关的 特征, 包括表层上皮发亮, 树枝状细胞和基质神经纤维弯曲. 在 2 例正常人 (4 只眼) 中, 作者发现一种新的角膜内皮表型, 他 们称之为“椒盐样内皮”, 但目前还不能确定这是正常角膜内皮 的形态学变异还是一种病理情况. 作者认为, 理解角膜形态学 翿年性改变是鉴别角膜生理性翿化和退行性疾病的关键. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650845 Wed, 01 Feb 2012 05:00:00 +0100 5650845 http://www.medworm.com/index.php?rid=5650844&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS016164201101222X%2Fabstract%3Frss%3Dyes La microscopía confocal in vivo (IVCM) ha aclarado aún más la comprensión de la diversidad morfológica de la córnea transparente con el proceso de envejecimiento. Hillenaar y otros (p. 241) identificaron 4 manifestaciones características del envejecimiento normal de la córnea: micropuntos estromales, pliegues en el estroma posterior, opacificación de la membrana de Descemet y córnea gutatta. Este estudio de observación de corte transversal incluyó 300 córneas de 75 hombres y 75 mujeres sanos. Además de las 4 manifestaciones características de la córnea en el proceso de envejecimiento, los autores identificaron otras manifestaciones independientes de la edad, que incluyen células epiteliales superficiales brillantes, células dendriformes y nervios estromales tortuosos. Ade... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650844 Wed, 01 Feb 2012 05:00:00 +0100 5650844 http://www.medworm.com/index.php?rid=5650843&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011011766%2Fabstract%3Frss%3Dyes In vivo confocal microscopy (IVCM) has yielded insight into the morphologic diversity of the transparent cornea in the aging eye. Hillenaar et al (p. 241) identified 4 characteristic manifestations of normal corneal aging: stromal microdots, folds in the posterior stroma, opacification of Descemet's membrane, and corneal guttae. The observational cross-sectional study involved 300 corneas of 75 healthy men and 75 healthy women. In addition to the 4 characteristic manifestations of the aging cornea, the authors identified some features that were age-independent, including bright superficial epithelial cells, dendriform cells, and tortuous stromal nerves. The authors also found a novel corneal endothelium phenotype in 4 normal eyes of 2 participants, which they named “salt and pepper endot... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650843 Wed, 01 Feb 2012 05:00:00 +0100 5650843 http://www.medworm.com/index.php?rid=5650842&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011012000%2Fabstract%3Frss%3Dyes (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650842 Wed, 01 Feb 2012 05:00:00 +0100 5650842 http://www.medworm.com/index.php?rid=5562601&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011009547%2Fabstract%3Frss%3Dyes The letter to the editor stated that we should have used high-resolution orbital imaging in the management of our patients. The letter cited literature on imaging and strabismus; however, none of these studies compared outcomes with and without orbital imaging in the management of restrictive strabismus. In fact, we are aware of no comparative studies on orbital imaging in the treatment of restrictive strabismus. Dr. Wright's experience is that orbital imaging is not helpful in the surgical management of anterior orbital restriction as described in our paper. High-resolution orbital imaging often misses significant anterior orbital scarring that causes restriction and can mislead the surgeon by showing lesions that are not causing restriction. Restrictive strabismus associated with conjunc... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562601 Sun, 01 Jan 2012 05:00:00 +0100 5562601 http://www.medworm.com/index.php?rid=5562600&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011009535%2Fabstract%3Frss%3Dyes I congratulate Strube et al in reporting their data on the amniotic membrane transplantation for surgical management of restrictive strabismus. Those of us who frequently perform complex strabismus surgeries certainly appreciate this study as it will provide us with an additional option to add to our armamentarium to treat these challenging patients. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562600 Sun, 01 Jan 2012 05:00:00 +0100 5562600 http://www.medworm.com/index.php?rid=5562599&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011008992%2Fabstract%3Frss%3Dyes We thank these authors for their insights, and do not disagree with much of what they say. In an institution with good equipment and image interpretation skills, it may be very reasonable to use spectral domain-optical coherence tomography (SD-OCT) and fundus autofluorescence (FAF) as the primary screening tools, with fields performed sporadically. However, it would have been hard for us to write a document to that effect to serve the country (or world) at large, when no definitive comparisons have yet been published to eliminate the use of visual fields. The new recommendations were needed primarily to address the uncritical use of fields and Amsler grids. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562599 Sun, 01 Jan 2012 05:00:00 +0100 5562599 http://www.medworm.com/index.php?rid=5562598&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011008980%2Fabstract%3Frss%3Dyes We read with interest the article entitled “Revised recommendations on screening for chloroquine and hydroxychloroquine retinopathy.” We commend the authors for offering guidelines on this important and common clinical situation; however, we seek clarification about their conclusions. The authors divided tests into those that are “objective” and those that are not as objective. Visual fields are grouped among the “not as objective” tests. We agree with the differentiation. We agree that both spectral domain-optical coherence tomography (SD-OCT) and fundus autofluorescence (FAF) are “objective tests” and the distinction made between the testing groups however, we wonder why, for the follow-up examinations, the authors state that: “We continue to recommend automated 10-2 fi... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562598 Sun, 01 Jan 2012 05:00:00 +0100 5562598 http://www.medworm.com/index.php?rid=5562597&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011009833%2Fabstract%3Frss%3Dyes We are writing in reply to the question posed by Lee et al about the hyperfluorescent lines parallel to the retinal vessels that showed differing extents of displacement, resulting in variable stretching of the retina, typically most pronounced inferiorly and with rotational displacement of the retina. We were aware of stretching of the retina after vitrectomy with gas injection, as pointed out, and are grateful for the advice. Although most patients may have monocular symptoms of metamorphopsia, the exact reason is not known. It is unclear whether the retinal stretching causes metamorphopsia. However, it is clear that, if the macula is translocated or there is stretching around the disc, cyclotorsional diplopia or awareness of a tilted image could be easily compensated for by the sensory ... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562597 Sun, 01 Jan 2012 05:00:00 +0100 5562597 http://www.medworm.com/index.php?rid=5562596&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011009821%2Fabstract%3Frss%3Dyes We read with interest the article by Shiragami et al on unintentional displacement of the retina after vitrectomy for rhegmatogenous retinal detachment, and the subsequent correspondence. We too have seen evidence of retinal displacement on autofluorescence images (taken with a Topcon camera, Tokyo, Japan) in eyes following vitrectomy for rhegmatogenous retinal detachment. We have, however, made a number of additional observations of relevance in consideration of the etiology and functional implications of this postoperative finding. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562596 Sun, 01 Jan 2012 05:00:00 +0100 5562596 http://www.medworm.com/index.php?rid=5562595&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011008414%2Fabstract%3Frss%3Dyes We appreciate the great interest of Drs. López-Guajardo and Benítez-Herreros and their valuable comments on our study. In our study, we reported a relatively low incidence (5.7%) of vitreous incarceration in the transconjunctival sutureless vitrectomy (TSV) sclerotomies evaluated with anterior segment OCT (AsOCT). The incidence was much lower than other studies measured with either Ultrasound biomicroscopy (UBM) or endoscopy. Attributing the discrepancy partly to the different imaging method used is reasonable. The Visante AsOCT (Carl Zeiss Meditec, Dublin, CA) we used in our study relies on 1310 nm wavelength light. The near-infrared spectra has good penetrability which can transverse semitransparent media, such as sclera or retinal pigment epithelium-choroid layers. The feasibility of... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562595 Sun, 01 Jan 2012 05:00:00 +0100 5562595 http://www.medworm.com/index.php?rid=5562594&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011008426%2Fabstract%3Frss%3Dyes We read with great interest the article by Chen et al in which they study transconjunctival sutureless vitrectomy (TSV) sclerotomies with anterior segment-optical coherence tomography (AsOCT). (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562594 Sun, 01 Jan 2012 05:00:00 +0100 5562594 http://www.medworm.com/index.php?rid=5562593&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011008785%2Fabstract%3Frss%3Dyes We thank Dr. Spaeth for his interest in our article. We agree with Dr. Spaeth that it is possible to fit a “line” through almost any collection of data, no matter how scattered they are. We aimed at highlighting this, and hopefully have demonstrated how misleading “lines” can be by plotting a linear as well as a lowess fit. We are not suggesting that lowess curves are the best way to graphically represent the relationship between the severity of visual field loss at presentation and the rate of progression but have at least demonstrated how misleading the traditional linear graphs can be. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562593 Sun, 01 Jan 2012 05:00:00 +0100 5562593 http://www.medworm.com/index.php?rid=5562592&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011008773%2Fabstract%3Frss%3Dyes Rao et al address an extremely important issue. However, their conclusions seem unjustified. They conclude that the rate of progression of visual field (VF) loss in glaucoma “is dependent upon the severity of VF loss at presentation.” They base this on a retrospective review of patients in their clinics. Methodologically they do not comment on a confounder that makes the results of such studies extremely suspect. Specifically, it is virtually certain that the patients were treated differently depending upon the stage of their glaucoma. Patients with what the authors call mild glaucoma almost certainly had mild treatment, whereas those with severe glaucoma almost certainly had severe treatment. It is likely that the treatments actually affected the rate of progression. It is also likely... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562592 Sun, 01 Jan 2012 05:00:00 +0100 5562592 http://www.medworm.com/index.php?rid=5562591&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011008918%2Fabstract%3Frss%3Dyes We concur with observations made by Yu et al regarding the unique characteristics of the keratoprosthesis-related endophthalmitis cases we reported recently. Although the rate of endophthalmitis in our series (12.5%) was similar to other published reports, the spectrum of the causative organisms represents the most striking departure from other series, with Gram-negative bacteria (3 eyes) and fungus (1 eye) isolated. The addition of vancomycin to the postoperative antibiotic regimen has improved protection against bacterial endophthalmitis. However, a slight increase in fungal infections without a change in the rate of fungal colonization over 1 year of surveillance has been documented by the same study group, and in the current era of vancomycin use, cases of endophthalmitis have been rep... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562591 Sun, 01 Jan 2012 05:00:00 +0100 5562591 http://www.medworm.com/index.php?rid=5562590&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011008906%2Fabstract%3Frss%3Dyes We read with great interest and appreciation the paper “Long-term vision outcomes and complications with the Boston type 1 keratoprosthesis” by Greiner et al. They conclude that keratoprosthesis implantation is a viable option for salvaging vision. However, a significant number of patients lost vision over the postoperative course. Endophthalmitis was documented in 5 eyes (12.5%) in their series, including 3 gram-negative and 1 fungal infection. The spectrum of infectious organisms differs from previous studies that found that gram-positive infections were most typical after keratoprosthesis surgery. Greiner et al comment that vancomycin prophylaxis might alter the ocular surface flora and encourage the selection of gram-negative and fungal infections. These infections occurred in pati... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562590 Sun, 01 Jan 2012 05:00:00 +0100 5562590 http://www.medworm.com/index.php?rid=5562589&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011008797%2Fabstract%3Frss%3Dyes We thank the authors of the letter for their comments and for the opportunity to reply to the statements and suggestions made. In the current trial, 100% of eyes in the group with the early model Intraocular Collamer Lenses (ICL) and 31% of eyes in the group with V4 ICL lenses completed the 10-year follow-up visit. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562589 Sun, 01 Jan 2012 05:00:00 +0100 5562589 http://www.medworm.com/index.php?rid=5562588&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011008761%2Fabstract%3Frss%3Dyes We read with great interest the article titled “Long-term Changes in Posterior Chamber Phakic Intraocular Collamer Lens Vaulting in Myopic Patients” by Schmidinger et al. The authors have highlighted the importance of reduction of vaulting with time, which should be taken into consideration while implanting phakic intraocular collamer lenses (ICL). (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562588 Sun, 01 Jan 2012 05:00:00 +0100 5562588 http://www.medworm.com/index.php?rid=5562587&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011009778%2Fabstract%3Frss%3Dyes We thank Raju et al for their comments concerning our paper “Associated Morbidity of Blepharitis.” We agree with them that Demodex is also a possible association with blepharitis. The ectopic parasite Demodex is the most common parasite in humans. It inhabits the eyelids, cilia, meibomian glands, face, and external otic tract. In the eyelids it lives deep in the meibomian glands and the sebaceous glands of the lash, and eat skin cells, hormones, and oils that accumulate within the hair follicle. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562587 Sun, 01 Jan 2012 05:00:00 +0100 5562587 http://www.medworm.com/index.php?rid=5562586&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS016164201100978X%2Fabstract%3Frss%3Dyes We read with interest the article by Nemet et al. The well written article has omitted a very important cause of blepharitis and associated morbidity– Demodex folliculorum. Tea tree oil shampoo can be effective in Demodex blepharitis and reduce the morbidity. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562586 Sun, 01 Jan 2012 05:00:00 +0100 5562586 http://www.medworm.com/index.php?rid=5562585&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011008025%2Fabstract%3Frss%3Dyes The Accreditation Council for Graduate Medical Education (ACGME) requires a certain number of hours of formal teaching in particular subjects in a fully accredited ophthalmology residency program. Fifty-two of 114 (45.6%) ophthalmology residency programs in the United States enroll 2 or 3 residents per year. These small programs may have limited expertise and resources to meet ACGME requirements in some subspecialties. They either send their residents for courses or invite experts from different institutions. Either method is expensive and requires time away from other responsibilities–both for the residents and the invited speaker. Webcast conferencing has been used as a tool for business communication/conferencing and education in fields like nursing, family medicine, and pathology. Ho... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562585 Sun, 01 Jan 2012 05:00:00 +0100 5562585 http://www.medworm.com/index.php?rid=5562584&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011008360%2Fabstract%3Frss%3Dyes We present our prospective case series on 450 enucleated adult eyes. We aimed to see whether currently recommended distances for pars plana sclerotomies as per age and lens status are appropriate for all adult eyes irrespective of the axial length and pars plana dimensions. Donor eyes rejected for keratoplasty were included in the study within 6 hours of enucleation and were injected with normal saline via the optic nerve to build up intraocular pressure (when necessary). Three 25 gauge (G) pins were introduced in the superotemporal, superonasal, and inferotemporal quadrants (1 each), strictly orthogonal to the sclera as described by Eckhardt et al at 3 mm, 3.5 mm, and 4 mm from the mid-limbus depending on whether the eye was aphakic, pseudophakic, or phakic respectively (; available at ht... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562584 Sun, 01 Jan 2012 05:00:00 +0100 5562584 http://www.medworm.com/index.php?rid=5562583&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011008372%2Fabstract%3Frss%3Dyes This study was approved by the Medical Ethics Committee of the University of Malaya Medical Centre (Reference Number 739.14) and it adhered to the tenets of Declaration of Helsinki. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562583 Sun, 01 Jan 2012 05:00:00 +0100 5562583 http://www.medworm.com/index.php?rid=5562582&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007834%2Fabstract%3Frss%3Dyes We report a rare case of a patient with dermatofibrosarcoma protuberans (DFSP) located on the lower eyelid. The lesion was accidentally scratched by a cat after it had been present for 3 months. Dermatofibrosarcoma protuberans is a rare, slow-growing soft tissue sarcoma of low-intermediate grade malignancy that originates from the dermis. It is locally aggressive and frequently recurs locally after incomplete excision, but distant metastasis is rare. The tumor occurs predominantly on the trunk followed by the proximal extremities and rarely on the head and neck. There are a small number of reports of DFSP developing in the eyelid and it is possible trauma of lesion site can accelerate the progression of DFSP. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562582 Sun, 01 Jan 2012 05:00:00 +0100 5562582 http://www.medworm.com/index.php?rid=5562552&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011010906%2Fabstract%3Frss%3Dyes With apologies, the first author's name in the Letter to the Editor entitled, “Conjunctival Melanoma” (Ophthalmology 2011;118:2307–8), should have appeared as Qasiem J. Nasser, MD. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562552 Sun, 01 Jan 2012 05:00:00 +0100 5562552 http://www.medworm.com/index.php?rid=5562551&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007573%2Fabstract%3Frss%3Dyes Spectral domain optical coherence tomography (SD-OCT) applied to the eye is rapidly expanding its scope of usefulness. In this issue of Ophthalmology, the respective authors of 2 different articles describe the use of “enhanced depth imaging” (EDI) to explore the optic disc, and in particular the lamina cribrosa, in the context of glaucoma. The lamina cribrosa is of special interest because the excavation of the optic nerve head, so characteristic of glaucoma in contrast to other optic atrophies, is related to the collapse and posterior bowing of the lamina cribrosa with widening of the scleral opening. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562551 Sun, 01 Jan 2012 05:00:00 +0100 5562551 http://www.medworm.com/index.php?rid=5562550&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011011055%2Fabstract%3Frss%3Dyes (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562550 Sun, 01 Jan 2012 05:00:00 +0100 5562550 http://www.medworm.com/index.php?rid=5562549&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011011341%2Fabstract%3Frss%3Dyes Li (p. 90) 等研究了 Fuchs'角膜内皮营养不良患者接受后弹 力层剥离自动角膜内皮移植 (DSAEK) 术后发生植片排斥反应 对内皮细胞的影响. 这项回顾性研究共有 415 例 (615 只眼) Fuchs'角膜内皮营养不 良的患者, 经过至少 6 个月随访, 作者 确认有 45 例 (7.3%) 发生排斥反应. 排斥最多发生在术后 12 个月和术后 18 个月. 记录 DSAEK 术后 1 年, 2 年, 3 年和 4 年角膜内皮丢失数量. 发生排斥的眼球 ECD 下降在所有时间点 都大于没有发生排斥的眼, 在术后 2 年和 3 年有明显差异. 考虑到随着时间流逝, 发生排斥的眼球 ECD 丢失更多, 作者认 为有必要确认患者的危险因素, 并预防发作. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562549 Sun, 01 Jan 2012 05:00:00 +0100 5562549 http://www.medworm.com/index.php?rid=5562548&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011010803%2Fabstract%3Frss%3Dyes Li y otros (p. 90) evaluaron los efectos del rechazo del injerto después de queratoplastia endotelial automatizada con denudamiento de la membrana de Descemet (DSAEK) en la pérdida de células endoteliales al cabo de un tiempo en pacientes con distrofia endotelial de Fuchs. En este estudio retrospectivo, que incluyó 615 ojos de 415 pacientes con distrofia endotelial de Fuchs, los autores identificaron 45 casos de rechazo del injerto (7,3%) en los pacientes con un seguimiento de al menos 6 meses. El mayor número de rechazos se presentó entre los meses 12 a 18 del postoperatorio. La pérdida de células endoteliales se determinó al término de 1, 2 3 y 4 años después de la DSAEK. En todas las fechas de corte, los ojos con un episodio de rechazo del injerto mostraron un mayor porcenta... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562548 Sun, 01 Jan 2012 05:00:00 +0100 5562548 http://www.medworm.com/index.php?rid=5562547&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011010438%2Fabstract%3Frss%3Dyes Li et al (p. 90) evaluated the effects of graft rejection following Descemet's stripping automated endothelial keratoplasty (DSAEK) on endothelial cell loss over time in patients with Fuchs' endothelial dystrophy. In this retrospective case study, which included 615 eyes of 415 Fuchs' dystrophy patients, the authors identified 45 cases of graft rejection (7.3%) in the patients with at least 6 months of follow up. The greatest number of rejections occurred between postoperative months 12 and 18. Endothelial cell loss was recorded at 1, 2, 3, and 4 years following DSAEK surgery. At all time points, eyes with a graft rejection episode had a greater percentage decline in endothelial cell density (ECD) than those eyes without graft rejection episodes. This was significant at 2 and 3 years posto... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562547 Sun, 01 Jan 2012 05:00:00 +0100 5562547 http://www.medworm.com/index.php?rid=5562546&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011011031%2Fabstract%3Frss%3Dyes (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562546 Sun, 01 Jan 2012 05:00:00 +0100 5562546 http://www.medworm.com/index.php?rid=5650857&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007354%2Fabstract%3Frss%3Dyes Conclusions: This is the first comparative clinical review examining adjustment of power of the sulcus-implanted IOL. We found that the IOL power should be adjusted according to the measured AL and predicted IOL power. For patients with a predicted IOL power from 18 to 25 D, power should be reduced by at least 1 D; for lenses >25 D, power should be reduced by 1.5 to 2 D. Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650857 Mon, 26 Dec 2011 05:00:00 +0100 5650857 http://www.medworm.com/index.php?rid=5650853&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007494%2Fabstract%3Frss%3Dyes Conclusions: Advanced AJCC T-stage, locally invasive tumors, and more pathologically aggressive tumors were at higher risk for recurrence. Inadequate initial therapy also was an important risk factor for recurrence. Treatment strategies should be affected by tumor staging at presentation. Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650853 Wed, 21 Dec 2011 05:00:00 +0100 5650853 http://www.medworm.com/index.php?rid=5650865&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007871%2Fabstract%3Frss%3Dyes Purpose: To evaluate the progression rate of macular and circumpapillary retinal nerve fiber layer (RNFL) thickness in advanced glaucomatous eyes using spectral domain optical coherence tomography (Cirrus HD-OCT, Carl Zeiss Meditec, Dublin, CA). Design: Longitudinal, observational study. Participants: A total of 98 eyes of 98 patients with advanced glaucoma (visual field [VF] mean deviation [MD] (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650865 Mon, 19 Dec 2011 05:00:00 +0100 5650865 http://www.medworm.com/index.php?rid=5650858&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007810%2Fabstract%3Frss%3Dyes Conclusions: Explantation because of postoperative subluxation or dislocation of CTR–IOL–capsular bag complexes occurred approximately 6.8 years after implantation in this series, providing further evidence that a fine line exists between zonular insufficiency that can be stabilized with the CTR alone and that requiring further support. Analyses of large series may help to define common factors associated with this complication, as well as surgical planning and employment of various endocapsular support devices to enhance postoperative zonular stabilization. Financial Disclosure(s): The authors have no proprietary or commercial interest in any materials discussed in this article. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650858 Fri, 09 Dec 2011 05:00:00 +0100 5650858 http://www.medworm.com/index.php?rid=5650866&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS016164201100738X%2Fabstract%3Frss%3Dyes Purpose: To determine the efficacy of a subconjunctival injection of hyaluronic acid (HA) with 5-fluorouracil (5FU) formulation as an adjunct in reviving bleb function by needling. Design: Prospective, randomized, controlled trial. Participants: Fifty patients with previous trabeculectomy and scheduled by the managing physician for a needling intervention. Methods: One eye of each patient was randomized to receive needling with HA-5FU mixture or needling with subconjunctival injection of 5FU solution alone. Main Outcome Measures: The primary outcome was the percentage of subjects with an intraocular pressure (IOP) (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650866 Wed, 07 Dec 2011 05:00:00 +0100 5650866 http://www.medworm.com/index.php?rid=5650852&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007469%2Fabstract%3Frss%3Dyes Conclusions: There was no significant difference in recurrence rates of pterygium after surgery with mitomycin C application between the CAU and CLAU groups, more remarkably in primary cases. Limbal damage was seen in some eyes with CLAU. Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650852 Wed, 07 Dec 2011 05:00:00 +0100 5650852 http://www.medworm.com/index.php?rid=5562560&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011008864%2Fabstract%3Frss%3Dyes Conclusions: Common features of posterior scleritis include concurrent anterior uveitis, disc swelling, and retinal striae. B-scan ultrasound demonstrating T-sign was the most useful confirmatory investigation in all cases. Systemic association is uncommon. Aggressive therapy with systemic corticosteroid achieves resolution mostly within the first year. Long-term immunosuppression is often required to prevent recurrence. Visual outcome is favorable. Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562560 Mon, 05 Dec 2011 05:00:00 +0100 5562560 http://www.medworm.com/index.php?rid=5562581&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006294%2Fabstract%3Frss%3Dyes Conclusions: Infective lacrimal gland ductulitis, commonly from Actinomyces infection, should be considered in patients with unexplained chronic mucopurulent conjunctivitis; the condition settles rapidly with surgery. Financial Disclosure(s): Proprietary or commercial disclosure may be found after the references. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562581 Thu, 01 Dec 2011 05:00:00 +0100 5562581 http://www.medworm.com/index.php?rid=5460228&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006166%2Fabstract%3Frss%3Dyes I applaud the editorial by the American Association for Pediatric Ophthalmology & Strabismus Research Committee regarding the lack of scientific evidence for the use of stem cell therapy for optic nerve hypoplasia and the potential for harm from such therapy. I would emphasize that the concerns expressed regarding stem cell treatment for optic nerve hypoplasia can be extended to optic nerve disease, both congenital and acquired, in general. As sight is considered by most persons the most important of their senses, it is not surprising that patients with optic nerve dysfunction regardless of the cause will go to any length to find a cure for their visual loss. I would call the readers' attention to a superb editorial in The Journal of the American Medical Association that discusses the dang... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5460228 Thu, 01 Dec 2011 05:00:00 +0100 5460228 http://www.medworm.com/index.php?rid=5460227&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007536%2Fabstract%3Frss%3Dyes Dr. Mudit Tyagi and Dr. Raja Narayanan raised interesting points about some limitations in our study, which we acknowledge. First, we agree that the time gap of 2 years between the baseline and second examination when assessments were made for subclinical cardiovascular disease (CVD) and diabetic retinopathy (DR) could bias some of the findings; we have therefore been careful not to conclude a causal relationship. To clarify glycemic status of our study participants, diabetes was confirmed by the glycemic status of the patient at baseline examination (concurrent to time when subclinical CVD was assessed). (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5460227 Thu, 01 Dec 2011 05:00:00 +0100 5460227 http://www.medworm.com/index.php?rid=5460226&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007524%2Fabstract%3Frss%3Dyes We read with interest the article titled “Is Diabetic Retinopathy Related to Subclinical Cardiovascular Disease” by Wong et al. We would like to congratulate the authors for assessing various parameters of subclinical cardiovascular disease (CVD) and their association with advanced-stage diabetic retinopathy (DR). We also agree with the authors in their conclusion that in persons with diabetes without a history of clinical CVD, the presence of advanced-stage DR is associated with subclinical coronary artery disease. However, we would like to seek a few clarifications regarding the methodology and the conclusions. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5460226 Thu, 01 Dec 2011 05:00:00 +0100 5460226 http://www.medworm.com/index.php?rid=5460225&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007512%2Fabstract%3Frss%3Dyes Thank you for responding to our Ophthalmic Technology Assessment (OTA): Assessment of Visual Function in Glaucoma. The authors note that micro-perimetry may supplant conventional white-on-white perimetry as the functional test of choice for glaucoma, and cite several references. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5460225 Thu, 01 Dec 2011 05:00:00 +0100 5460225 http://www.medworm.com/index.php?rid=5460224&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007500%2Fabstract%3Frss%3Dyes The recent report from the American Academy of Ophthalmology on current methodology for assessment of visual function in glaucoma is timely and comprehensive; however, with all due respect to the distinguished authors, is incomplete. The report fails to notice microperimetry, which is currently used in clinical practice, and which will probably replace standard automated perimetry (SAP) in our offices within the next decade. This bold statement is based on recent developments in clinical practice that are bringing microperimetry very quickly to be the method of choice for assessment of residual visual function in retina cases, as well as in glaucoma. Microperimetry, which in the past was used solely as a laboratory modality for research, moved in the last few years into the office as a mod... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5460224 Thu, 01 Dec 2011 05:00:00 +0100 5460224 http://www.medworm.com/index.php?rid=5460223&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011008712%2Fabstract%3Frss%3Dyes The authors thank Cloke and Lim for their critical reading of our manuscript. We agree with their observation that deep anterior lamellar keratoplasty (DALK) procedures are not always extraocular in the strict sense of the word. Although we would argue that there is still a potential clinical difference, however defined, between the risks of an “open-sky” penetrating keratoplasty (PK) and a successful DALK. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5460223 Thu, 01 Dec 2011 05:00:00 +0100 5460223 http://www.medworm.com/index.php?rid=5460222&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011008700%2Fabstract%3Frss%3Dyes Reinhart et al have provided an excellent review, comparing deep anterior lamellar keratoplasty (DALK) with penetrating keratoplasty (PK). However, there are some issues we would like to raise. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5460222 Thu, 01 Dec 2011 05:00:00 +0100 5460222 http://www.medworm.com/index.php?rid=5460221&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007858%2Fabstract%3Frss%3Dyes Dr. Brown has made a number of assertions regarding our manuscript that warrant a response. She points out that we failed to provide an adequate description of our pupil measurement technique. We acknowledge that we should have provided a detailed description of our pupil measurement procedures in the manuscript. Although the omission was regrettable, this does not mean that the pupil size measurements were performed incorrectly or that our data is inaccurate. Our pupil measurement technique is described in detail as follows: Patients were dark adapted for 2 minutes in a calibrated ETDRS testing lane at 1 lux ambient light as measured by a luxmeter. All sources of light leak were eliminated from the testing lane. Patients were measured prior to having any bleaching tests (i.e., topography,... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5460221 Thu, 01 Dec 2011 05:00:00 +0100 5460221 http://www.medworm.com/index.php?rid=5460220&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007846%2Fabstract%3Frss%3Dyes I read with concern the article by Chan and Manche regarding preoperative pupil size and postoperative vision quality after LASIK. Two lengthy paragraphs were dedicated to subject clinical characteristics and a precise description of the surgical procedure. Measurement of pupil diameter was described in a single sentence in which the light level was stated to be “mesopic” (which includes ambient illumination ranging from the most dimly lit restaurant to the windowed office where I currently sit), and duration of dark adaptation and control of accommodation were not mentioned. The Colvard pupillometer was used but we are not told by whom, i.e., an investigator, one technician, or several technicians over time. Pupil size was recorded to the tenth of a millimeter, which is beyond the pre... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5460220 Thu, 01 Dec 2011 05:00:00 +0100 5460220 http://www.medworm.com/index.php?rid=5460219&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006774%2Fabstract%3Frss%3Dyes The recent article on intraocular lens (IOL) power calculations with the IOLMaster (Carl Zeiss Meditec, Dublin, CA) in long cataractous eyes examined the performance of 5 formulas including the Holladay 2. One of the 7 variables used by the Holladay 2 formula to calculate the IOL power is crystalline lens thickness (CTL), but CTL is not measured by the IOLMaster. In the article, IOLMaster was the sole biometric tool mentioned, which made me conclude that the CTL variable was ignored. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5460219 Thu, 01 Dec 2011 05:00:00 +0100 5460219 http://www.medworm.com/index.php?rid=5460218&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS016164201100844X%2Fabstract%3Frss%3Dyes Thank you for your response to our manuscript evaluating the effects of treatment (specifically topical corticosteroids) on the development of cataract in patients with chronic uveitis associated with juvenile idiopathic arthritis (JIA). Although the authors are correct that 45% of eyes with JIA uveitis had had either cataract or cataract surgery, this is the frequency of occurrence at the time in which patients presented to our clinic rather than the cataracts that were diagnosed while patients were under observation for the study. During the observed follow up, 9 of 60 eyes with chronic uveitis and at risk for developing cataract, developed cataract for an incidence rate of 0.04 per eye-year (/EY; 95% confidence interval = 0.02/EY to 0.09/EY) over a mean follow up of 4.6 years. Sabri et ... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5460218 Thu, 01 Dec 2011 05:00:00 +0100 5460218 http://www.medworm.com/index.php?rid=5460217&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011008451%2Fabstract%3Frss%3Dyes This study looked at all children with juvenile arthritis associated uveitis who were seen in the Ocular Immunology Clinic at the Wilmer Eye Institute between July 1984 and August 2005. The study group included 75 children in total, and found that 22.5% of eyes had cataract and an additional 23.1% of eyes had already undergone cataract surgery by the time of presentation. Therefore, almost half of all the eyes (45.6%) had experienced cataract. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5460217 Thu, 01 Dec 2011 05:00:00 +0100 5460217 http://www.medworm.com/index.php?rid=5460216&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006841%2Fabstract%3Frss%3Dyes Retinitis pigmentosa (RP) is a clinically and genetically heterogeneous set of progressive retinal disorders. To date, mutations in 53 genes have been described to cause RP (http://www.sph.uth.tmc.edu/Retnet/ accessed June 22, 2011). However, these genes account for disease in a little over half of all patients. Also, it is well known that several genes cause distinct or partially overlapping clinical phenotypes. Mutations in the SPATA7 gene have been associated with a severe congenital retinal dystrophy (Leber congenital amaurosis [LCA]) and a form of Juvenile RP. Therefore, a correlation between the severity of mutant alleles in SPATA7 and the clinical phenotype has been established. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5460216 Thu, 01 Dec 2011 05:00:00 +0100 5460216 http://www.medworm.com/index.php?rid=5460215&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS016164201100683X%2Fabstract%3Frss%3Dyes The standard of care for myopic choroidal neovascularization (CNV) has been photodynamic therapy (PDT) since the VIP1 study concluded that PDT increased chances of stabilization or improvement of visual acuity (VA). In recent years, antiangiogenic drugs have been used off-label to treat CNV secondary to high myopia. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5460215 Thu, 01 Dec 2011 05:00:00 +0100 5460215 http://www.medworm.com/index.php?rid=5460214&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007391%2Fabstract%3Frss%3Dyes We describe a periocular and ocular herpetic infection in a patient treated with ICS. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5460214 Thu, 01 Dec 2011 05:00:00 +0100 5460214 http://www.medworm.com/index.php?rid=5460213&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007883%2Fabstract%3Frss%3Dyes Corneal collagen cross-linking (CXL) with riboflavin and ultraviolet A (UVA) is a technique to strengthen corneal tissue using riboflavin as a photosensitizer and UVA to increase the formation of intra- and inter-fibrillar covalent bonds by photosensitized oxidation. Today, CXL is limited to eyes with a corneal thickness of at least 400 μm due to concerns about the cytotoxic effect on the endothelium, crystalline lens, and other intraocular tissues. This threshold has limited its performance in some eyes with advanced stages of corneal ectasia. The downside of the current pachymetric limitation is that patients with keratoconus or keratectasia often have corneas that are thinner than the 400 μm threshold. Transepithelial CXL, CXL with customized pachymetric-guided epithelial debridement ... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5460213 Thu, 01 Dec 2011 05:00:00 +0100 5460213 http://www.medworm.com/index.php?rid=5460212&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007408%2Fabstract%3Frss%3Dyes Collagen crosslinking (CXL) by riboflavin and ultraviolet-A (UVA) stabilizes progressive keratoconus by addressing some of the underlying pathophysiological mechanisms of the disease. Collagen crosslinking photopolymerization creates additional chemical bonds (crosslinks) within the anterior 200–300 μm of the corneal stroma to increase biomechanical rigidity. There is only minimal UVA exposure to the internal structures of the eye. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5460212 Thu, 01 Dec 2011 05:00:00 +0100 5460212 http://www.medworm.com/index.php?rid=5460211&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006828%2Fabstract%3Frss%3Dyes The iris-fixated phakic intraocular lenses (PIOLs), the Artisan and foldable Artiflex PIOLs (Ophtec BV, Groningen, The Netherlands), are widely accepted to treat moderate and high myopia. However, since this type of PIOL is fixated on iris tissue, the potential for chronic inflammation raises concerns about the long-term safety of the PIOL design, especially in Asian eyes with brown irides, which predispose to ocular inflammation. We quantitatively investigated the extent of postoperative inflammation after PIOL implantation using a laser flare cell meter in Asian patients with brown irides. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5460211 Thu, 01 Dec 2011 05:00:00 +0100 5460211 http://www.medworm.com/index.php?rid=5460210&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011009456%2Fabstract%3Frss%3Dyes Conclusions: Duplication of the approach used in the DRCR.net randomized clinical trial to treat DME involving the center of the macula with intravitreal ranibizumab may not be practical in clinical practice, but likely can be emulated based on an understanding of the underlying rationale for the study protocol. Inherent differences between a web-based treatment algorithm and a clinical approach may lead to differences in outcomes that are impossible to predict. The closer the clinical approach is to the algorithm used in the study, the more likely the outcomes will be similar to those published.Financial Disclosure(s): Proprietary or commercial disclosure may be found after the references. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5460210 Thu, 01 Dec 2011 05:00:00 +0100 5460210 http://www.medworm.com/index.php?rid=5460180&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011005495%2Fabstract%3Frss%3Dyes The use of optical coherence tomography (OCT) in pediatric ophthalmology is in its infancy. For perspective, one need only count the number of articles that PubMed lists as of this writing for OCT associated with retina (2434), glaucoma (903), or the anterior segment (521). For pediatric ophthalmology, there are fewer citations, with less than 20 dealing with infants. Thus, the use of OCT to study the developing retina of preterm infants appearing in this issue of Ophthalmology is pioneering. Previous studies of the developing retina were largely based on histological analyses from postmortem specimens which are subject to fixation artifact, shrinkage, represent a single moment in time, and often include disease-related changes. Optical coherence tomography can be used to study healthy inf... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5460180 Thu, 01 Dec 2011 05:00:00 +0100 5460180 http://www.medworm.com/index.php?rid=5460179&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011010049%2Fabstract%3Frss%3Dyes (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5460179 Thu, 01 Dec 2011 05:00:00 +0100 5460179 http://www.medworm.com/index.php?rid=5460178&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011009791%2Fabstract%3Frss%3Dyes Maldonado (p. 2315) 等用便携式频谱光学相关断层扫描 (SDOCT) 检查了 31 例早产新生儿, 观察人类视网膜活体细胞层的发育以及中心凹亚细胞结构的特化, 发现在早产儿出生后人类中心凹仍在发育. 这些新生儿的受孕后年龄为 31∼41 周 (受孕后年龄又称矫正胎龄, 即胎龄和胎儿 出生后实际日龄之和), 在这些新生儿中, 观察到的体征有亚细胞结构的迁移, 再分布和生长, 还包括中心凹成熟时中心凹外的视网膜细胞层的移位和相对方 向内/外节层的明显形成. 作者有个意外发现, 早产儿中有 58% 发生黄斑囊样水肿, 这可能影响了内层中央凹的成熟. 他们总 结到, 确定人类中心凹发育的时间表, 有助于深入了解疾病活 动性... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5460178 Thu, 01 Dec 2011 05:00:00 +0100 5460178 http://www.medworm.com/index.php?rid=5460177&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011009808%2Fabstract%3Frss%3Dyes Usando un tomógrafo de coherencia óptica de dominio espectral (SDOCT), Maldonado y otros (p. 2315) describen el desarrollo de las capas celulares vivas de la retina humana y de la especialización subcelular en la fóvea en los ojos de 31 neonatos prematuros– lo que demuestra que el desarrollo de la fóvea continua después del nacimiento prematuro. En estos neonatos, con una edad postmenstrual (PMA) (PMA = edad gestacional en semanas + edad cronológica), se observaron varios signos de migración, redistribución y crecimiento de las estructuras subcelulares, incluyendo desplazamiento de las capas retinianas más allá del centro foveal a medida que madura la fóvea, y la formación progresiva de la banda del segmento interno/externo en dirección opuesta. Los autores señalan un hall... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5460177 Thu, 01 Dec 2011 05:00:00 +0100 5460177 http://www.medworm.com/index.php?rid=5460176&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011009481%2Fabstract%3Frss%3Dyes Using portable spectral domain optical coherence tomography (SD-OCT), Maldonado et al (p. 2315) describe the development of living cellular layers of the human retina and of subcellular specialization at the fovea in the eyes of 31 premature neonates–demonstrating that human foveal development continues after premature birth. In these neonates, ages 31 to 41 weeks postmenstrual age PMA (PMA = gestational age in weeks + chronological age), several signs of migration, redistribution, and growth of subcellular structures were observed, including displacement of retinal layers out of the foveal center as the fovea matured, and the progressive formation of the inner/outer segment band in the opposite direction. The authors pointed to an unexpected finding: the presence of cystoid macular edem... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5460176 Thu, 01 Dec 2011 05:00:00 +0100 5460176 http://www.medworm.com/index.php?rid=5460175&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011010001%2Fabstract%3Frss%3Dyes (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5460175 Thu, 01 Dec 2011 05:00:00 +0100 5460175 http://www.medworm.com/index.php?rid=5650881&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007822%2Fabstract%3Frss%3Dyes Conclusions: Slotted plaque radiation therapy allows peripapillary, juxtapapilary, and circumpapillary choroidal melanomas (and a safety margin) to be included in the radiation targeted zone. Normalization of the plaque position beneath the tumor appears to increase RON and improve local control. Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650881 Wed, 30 Nov 2011 05:00:00 +0100 5650881 http://www.medworm.com/index.php?rid=5650870&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS016164201100741X%2Fabstract%3Frss%3Dyes Purpose: Systemic complement activation is associated with age-related macular degeneration (AMD) and has mainly been attributed to a risk allele in the complement factor H (CFH) gene. Whether other important AMD genes also influence complement activation is unclear. In the present case-control study, complement activity and concentrations of complement components and their activation products are measured in AMD patients and in unaffected controls and correlated with genetic variants in the CFH, ARMS2, C3, CFI, and CFB genes. Design: Case-control study. Participants: A cohort of 197 confirmed AMD patients and 150 unaffected age-matched controls were recruited prospectively for the study. Methods: Hemolytic complement assays (AP50, CP50, and LP50), complement components (C3, CFB, CF... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650870 Wed, 30 Nov 2011 05:00:00 +0100 5650870 http://www.medworm.com/index.php?rid=5650868&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007974%2Fabstract%3Frss%3Dyes Conclusions: There is no significant difference in VA outcomes between IVB monotherapy versus IVB/PDT combination therapy. The use of IVB alone or in combination with PDT results in significant visual stabilization in the majority of patients with CNV secondary to POHS. Financial Disclosure(s): Proprietary or commercial disclosure may be found after the references. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650868 Wed, 30 Nov 2011 05:00:00 +0100 5650868 http://www.medworm.com/index.php?rid=5650863&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006944%2Fabstract%3Frss%3Dyes Conclusions: Patients with focal optic disc damage had faster rates of visual field change and a tendency toward faster rates of optic disc deterioration when compared with patients with diffuse and sclerotic optic disc damage, despite similar IOP reductions during follow-up. Financial Disclosure(s): Proprietary or commercial disclosure may be found after the references. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650863 Wed, 30 Nov 2011 05:00:00 +0100 5650863 http://www.medworm.com/index.php?rid=5650860&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007342%2Fabstract%3Frss%3Dyes Conclusions: Angle width is largely dependent on variations in ACA, ACV, and LV. A predictive model comprising 6 quantitative ASOCT parameters explained more than 80% of the variability of angle width and may have implications for screening for angle closure. Financial Disclosure(s): Proprietary or commercial disclosure may be found after the references. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650860 Fri, 25 Nov 2011 05:00:00 +0100 5650860 http://www.medworm.com/index.php?rid=5650864&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS016164201100786X%2Fabstract%3Frss%3Dyes Conclusions: There is no decrement in VF performance or reliability when patients undergo simultaneous testing with another patient in the same room. Busy clinical practices may be able to minimize costs and maximize efficiency by having 1 technician simultaneously supervise more than 1 test-taker in the same space. Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650864 Wed, 23 Nov 2011 05:00:00 +0100 5650864 http://www.medworm.com/index.php?rid=5562570&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006889%2Fabstract%3Frss%3Dyes Conclusions: Locally administered sirolimus was well-tolerated with minimal systemic exposure at all doses tested in this small phase I population. These findings support advancing the present sirolimus formulation into phase II studies. Financial Disclosure(s): Proprietary or commercial disclosure may be found after the references. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562570 Wed, 23 Nov 2011 05:00:00 +0100 5562570 http://www.medworm.com/index.php?rid=5562564&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006324%2Fabstract%3Frss%3Dyes Conclusions: There is a trend toward a greater percentage of ECD loss with time in eyes experiencing graft rejection after DSAEK surgery. Financial Disclosure(s): Proprietary or commercial disclosure may be found after the references. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562564 Wed, 23 Nov 2011 05:00:00 +0100 5562564 http://www.medworm.com/index.php?rid=5562561&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006312%2Fabstract%3Frss%3Dyes Conclusions: Approximately two thirds of the patients reached an ACC score of zero within 28 days, after only receiving 1 iontophoresis treatment. The lower doses seemed to be the most effective, and treatments were well-tolerated. Financial Disclosure(s): Proprietary or commercial disclosure may be found after the references. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562561 Wed, 23 Nov 2011 05:00:00 +0100 5562561 http://www.medworm.com/index.php?rid=5650873&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006932%2Fabstract%3Frss%3Dyes Conclusions: Colobomatous defects were the most common phenotype within this spectrum of anomalies in the United Kingdom. The high frequency of posterior segment colobomatous involvement means that a dilated fundal examination should be made in all cases. The significant visual and systemic morbidity in affected children underlines the importance of a multidisciplinary approach to management. Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650873 Mon, 07 Nov 2011 05:00:00 +0100 5650873 http://www.medworm.com/index.php?rid=5650867&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS016164201100755X%2Fabstract%3Frss%3Dyes Conclusions: A greater number of intravitreal anti-vasular endothelial growth factor injections is associated with an increased risk for IOP elevation >5 mmHg on ≥2 consecutive visits in eyes with neovascular AMD receiving intravitreal ranbizumab and/or bevacizumab. Financial Disclosure(s): Proprietary or commercial disclosure may be found after the references. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650867 Mon, 07 Nov 2011 05:00:00 +0100 5650867 http://www.medworm.com/index.php?rid=5650859&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007329%2Fabstract%3Frss%3Dyes Conclusions: The ICL vaulting based on only the horizontal compression could not be quantitatively predicted. Additional factors, such as vertical compression by the iris, dampening effect of the ciliary sulcus structure, or innate ICL vault, should be considered to avoid unexpected vaulting after ICL implantation. Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650859 Mon, 07 Nov 2011 05:00:00 +0100 5650859 http://www.medworm.com/index.php?rid=5650855&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007421%2Fabstract%3Frss%3Dyes Objective: To compare deep anterior lamellar keratoplasty (DALK) with penetrating keratoplasty (PK) in eyes with corneal diseases not involving the corneal endothelium (keratoconus, scars after infectious keratitis, stromal dystrophies, and trauma). Design: Retrospective, comparative case series. Participants: One hundred forty-two consecutive DALK (DALK group; big-bubble technique or manual lamellar dissection using a slitlamp) and 142 matched PK (PK group). Methods: Three models were used to describe the postoperative outcomes of the endothelial cell density. A joint regression model was used to predict long-term graft survival. Visual acuity, ultrasound pachymetry, specular microscopy, and optical coherence tomography (OCT) findings were recorded. Main Outcome Measures: Postope... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650855 Mon, 07 Nov 2011 05:00:00 +0100 5650855 http://www.medworm.com/index.php?rid=5366654&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011004283%2Fabstract%3Frss%3Dyes We would like to express our gratitude to Dr. Dastiridou et al for their interest in and comments regarding our article. Because indocyanine green angiography is performed routinely to diagnose age-related macular degeneration (AMD) in our outpatient clinic, we were able to exclude cases of polypoidal choroidalvaculopathy (PCV) and retinal angiomatous proliferation (RAP). Therefore, the results of our study were confined to typical AMD, not AMD including PCV and RAP. The results of a recent study conducted by Nomura et al suggested an association between posterior vitreous attachment and typical AMD. However, this association was not evident in PCV. Further studies will clearly be required to assess the vitreomacular relationship in cases involving PCV and RAP. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5366654 Tue, 01 Nov 2011 04:00:00 +0100 5366654 http://www.medworm.com/index.php?rid=5366653&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011004295%2Fabstract%3Frss%3Dyes We read with great interest the study by Lee and Koh, entitled “Effects of vitreomacular adhesion on anti-vascular endothelial growth factor (VEGF) treatment for exudative age-related macular degeneration,” on the association between vitreomacular adhesion (VMA) and pharmacological resistance to anti-VEGF intravitreal injections for exudative age-related macular degeneration (AMD). (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5366653 Tue, 01 Nov 2011 04:00:00 +0100 5366653 http://www.medworm.com/index.php?rid=5366652&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006701%2Fabstract%3Frss%3Dyes We thank Drs. Naumann and Volcker for their comments regarding our article. We agree with them that the presence of ciliary body detachment and ocular hypotony in some cases raises a “chicken or the egg” dilemma. Even if longitudinal studies should prove our statement, we believe, the finding of ciliary body detachment in myotonic dystrophy type 1 (DM1) patients with normal intraocular pressure (IOP) implies that ciliary body detachment precedes the onset hypotony. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5366652 Tue, 01 Nov 2011 04:00:00 +0100 5366652 http://www.medworm.com/index.php?rid=5366651&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006713%2Fabstract%3Frss%3Dyes With interest we have read the article from Rosa et al. We agree that ciliary body detachment (CBD) is a frequent finding in eyes with ocular hypotony (Völcker et al). Following blunt or penetrating ocular trauma or surgery the sequence of events is clear; the unilateral CBD is a nonspecific complication that may further aggravate the persisting ocular hypotony. However, the data presented by Rosa et al do not prove that low intraocular pressure “results” from the usually bilateral CBD in myotonic dystrophy. The CBD just as likely might develop as a nonpathognomonic consequence of hypotony, a hen-egg-dilemma. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5366651 Tue, 01 Nov 2011 04:00:00 +0100 5366651 http://www.medworm.com/index.php?rid=5366650&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006075%2Fabstract%3Frss%3Dyes The letter written by Pagnoulle et al of the company Physiol SA explains that the spectral transmission curve of their Physiol Slim Flex lens (PhysIOL SA, Liège, Belgium), measured by us and published in our article, may be wrong. Pagnoulle et al say that this curve is similar to that of their Physiol Hydriol lens, which we also measured and they state that, in this case, our determinations are indeed correct. They suggest that perhaps a slight tilt of the lens might have caused this discrepancy, because as they admit, the spectrophotometer we used is highly accurate. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5366650 Tue, 01 Nov 2011 04:00:00 +0100 5366650 http://www.medworm.com/index.php?rid=5366649&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006063%2Fabstract%3Frss%3Dyes The article of Artigas published in your journal caught our attention. We were surprised by the discrepancy in the transmittance curves of the Hydriol 60C and the SlimFlex (Physiol, Belgium) found by the authors that are respectively a C-loop and a 4-haptic intraocular lens (IOL) made with the same raw material; these essential data are part of the file of the Conformité Européenne (CE) mark. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5366649 Tue, 01 Nov 2011 04:00:00 +0100 5366649 http://www.medworm.com/index.php?rid=5366648&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007482%2Fabstract%3Frss%3Dyes We read with great interest the paper by McCarthy et al concerning intraocular lens (IOL) power calculation after refractive corneal surgery published in the May 2011 issue. They undertook significant effort to perform such a study in a large number of patients, and we congratulate them. We would like to thank them because they tested, among the others, the method we previously described (R factor). Unfortunately, we found some errors in the paper. First, they included our method among those that require information from the prior laser surgery and named these methods “historical.” Unfortunately, this is not true, as our method does not require knowledge of the history of the patient, and to the best of our knowledge, was the first among such methods to be published, (maybe for this it... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5366648 Tue, 01 Nov 2011 04:00:00 +0100 5366648 http://www.medworm.com/index.php?rid=5366647&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006890%2Fabstract%3Frss%3Dyes We appreciate the comments submitted by Drs. Nasser and Esmaeli. Our report was an extensive analysis of a large cohort of 382 patients with a rare condition (conjunctival melanoma), in which data was retrospectively collected over a 33-year period. The clinical data was relatively complete as each patient was managed by our team and clinical information was diligently recorded at each visit. The histopathology data was scantier as this was extracted from pathology reports by various pathologists over a 3-decade period. The variability in pathology interpretation, tumor measurement, and invasive features precluded consistent recording of those variables. It would have been ideal to examine the histopathology slides of each case but many were not available. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5366647 Tue, 01 Nov 2011 04:00:00 +0100 5366647 http://www.medworm.com/index.php?rid=5366646&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006907%2Fabstract%3Frss%3Dyes Shields et al reported their extensive and valuable clinical observations in 382 consecutive patients with conjunctival melanoma. The authors provide a detailed and very useful overview of the clinical risk factors associated with orbital invasion, metastasis, and death in a significantly large series of patients with conjunctival melanoma. We wonder if the authors have information about histologic tumor thickness (depth of invasion), histologic ulceration, and other histologic features that have been reported to correlate with clinical outcomes for conjunctival melanoma, particularly in relation to the risk of regional lymph node metastasis, distant metastasis, and death. Shields et al point out that the nodular type of conjunctival melanoma, which is a subtype known for its aggressive gr... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5366646 Tue, 01 Nov 2011 04:00:00 +0100 5366646 http://www.medworm.com/index.php?rid=5366645&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006804%2Fabstract%3Frss%3Dyes We thank Marcus Ang, Jodhbir S. Mehta, Frank J.H.M. van den Biggelaar, Yanny Y.Y. Cheng, and Rudy M.M.A. Nuijts for their generous comments and additional observations. The 9 pages of our manuscript, as well as the 35 pages of the supplemental online appendix (both published in Ophthalmology) were extensively revised and shortened. Specifically, 2 of the deleted sections addressed applications of deep anterior lamellar keratoplasty (DALK) that Ang and Mehta identify. These applications were deemed to be somewhat peripheral to the objectives of the ophthalmic technology assessment, but are reprinted here. “Therapeutic indications, or the removal of infected corneal tissue when medical therapy alone has failed to stabilize the eye, have also been managed with DALK. This includes treatment ... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5366645 Tue, 01 Nov 2011 04:00:00 +0100 5366645 http://www.medworm.com/index.php?rid=5366644&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006798%2Fabstract%3Frss%3Dyes We read with interest the recent Ophthalmic Technology Assessment (OTA) published in Ophthalmology, “Deep Anterior Lamellar Keratoplasty as an Alternative to Penetrating Keratoplasty.” Although we found this to be an excellent summary of the comparative outcomes of penetrating keratoplasty (PK) and deep anterior lamellar keratoplasty (DALK), there were a few points not mentioned that we felt are also pertinent when comparing these 2 procedures. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5366644 Tue, 01 Nov 2011 04:00:00 +0100 5366644 http://www.medworm.com/index.php?rid=5366643&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006786%2Fabstract%3Frss%3Dyes Reinhart et al provided an excellent overview of the published literature on deep anterior lamellar keratoplasty (DALK) compared with penetrating keratoplasty (PK). To each of the selected articles, a methodologist assigned ratings of level of evidence, ranging from level I (well-designed and well-conducted randomized clinical trials) to level III (case series, case reports, and poor-quality case-control or cohort studies). Eleven comparative studies were included, showing results from level II and level III studies. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5366643 Tue, 01 Nov 2011 04:00:00 +0100 5366643 http://www.medworm.com/index.php?rid=5366642&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011004581%2Fabstract%3Frss%3Dyes We have previously reported 11 eyes (patients) out of 211 intravitreal injections with development or progression of tractional retinal detachment (TRD) with decrease best-corrected visual acuity (BCVA) after intravitreal bevacizumab (Avastin; Genentech Inc., San Francisco, CA) prior to vitrectomy for the management of proliferative diabetic retinopathy (PDR) for an incidence of 5.2%. Most patients had poorly controlled diabetes mellitus associated with elevated HbA1c, insulin administration, PDR refractory to pan-retinal photocoagulation (PRP), and longer time between intravitreal bevacizumab and vitrectomy. The purpose of this study was to determine risk factors for the progression or development of tractional retinal detachment following intravitreal bevacizumab (IVB) as an adjuvant to ... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5366642 Tue, 01 Nov 2011 04:00:00 +0100 5366642 http://www.medworm.com/index.php?rid=5366641&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006968%2Fabstract%3Frss%3Dyes The neodymium:YAG (Nd:YAG) laser radiation has been reported in several studies to cause damage to the foldable intraocular lens (IOL). The current generation of foldable IOLs, which includes the silicone and acrylic IOLs, are more resistant to damage by Nd:YAG laser photodisruption than the rigid polymethyl methacrylate (PMMA) lenses. The laser energy used, the accuracy of laser focusing, proximity of the IOL to the posterior capsule, the thickness of the IOL, and the laser-resistant properties of the IOL contribute to IOL damage. In vitro studies of Nd:YAG laser damage threshold of foldable IOLs, which included silicone, hydrophobic and hydrophilic lenses has shown 50% incidence damage threshold below the normal level in clinical practice. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5366641 Tue, 01 Nov 2011 04:00:00 +0100 5366641 http://www.medworm.com/index.php?rid=5366640&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011005124%2Fabstract%3Frss%3Dyes Bullous keratopathy is a corneal disease caused by endothelium decompensation. Patients with bullous keratopathy may present with reduced vision and ocular pain related to epithelial damage and stromal edema. Painful bullous keratopathy is associated with severe limitations in the activities of daily living, insomnia, low productivity, and poor quality of life. Penetrating or endothelial keratoplasty are the treatments of choice for alleviating pain and restoring vision; however, they are not elective surgeries in most centers worldwide and the waiting list for corneal tissue can be very long. Considering the good outcomes after phototherapeutic keratectomy (PTK) for relieving pain in symptomatic bullous keratopathy as a result of the corneal healing process, decreased corneal sensitivity,... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5366640 Tue, 01 Nov 2011 04:00:00 +0100 5366640 http://www.medworm.com/index.php?rid=5366631&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS016164201100830X%2Fabstract%3Frss%3Dyes Degenerative diseases such as age-related macular degeneration (AMD) and retinitis pigmentosa (RP) primarily affect the photoreceptors, ultimately resulting in significant loss of vision. Retinal prostheses aim to elicit neural activity in the remaining retinal cells by detecting and converting light into electrical stimuli that can then be delivered to the retina. The concept of visual prostheses has existed for more than 50 years and recent progress shows promise, yet much remains to be understood about how the visual system will respond to artificial input after years of blindness that necessitate this type of prosthesis. This review focuses on 3 major areas: the histopathologic features of human retina affected by AMD and RP, current results from clinical trials, and challenges to over... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5366631 Tue, 01 Nov 2011 04:00:00 +0100 5366631 http://www.medworm.com/index.php?rid=5366612&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007561%2Fabstract%3Frss%3Dyes Measuring—and ultimately paying for—quality medical outcomes is a fundamental component of many efforts to reign in the ongoing escalation of costs of medical care. Currently, physicians and health care systems are paid for providing quantity of services without correlation to the quality of the services. Certainly there are secondary quality systems in place, but typically these systems rely on a set of standards that define minimal required systematic behaviors rather than outcomes. In contrast, for many endeavors in a capitalist economy, outcomes are inherent in the compensation, whether you are a professional athlete, financial analyst, business owner, or manufacturer. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5366612 Tue, 01 Nov 2011 04:00:00 +0100 5366612 http://www.medworm.com/index.php?rid=5366611&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011009079%2Fabstract%3Frss%3Dyes (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5366611 Tue, 01 Nov 2011 04:00:00 +0100 5366611 http://www.medworm.com/index.php?rid=5366610&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011009493%2Fabstract%3Frss%3Dyes Weiland (p. 2227) 等在这篇报道中阐述了人工视网膜的最 新进展, 尤其是在临床方面, 并鼓励大家继续关注这个领域. 他们指出此类技术最近取得了关键性突破, 在 2011 年早些 时候, the Second Sight Medical Products 公司 (SSMP) ARGUS II 有一种产品获得 CE Mark 标志认证. 该产品是基于人工耳蜗 技术, 有 60 个电极和一个外置相机, 可以将图像信息无线传 输到植入体. 在临床试验中, 所有患者都可以在电刺激下 感受到光. 此外, 当本系统打开时, 所有 22 例患者中, 有 72.5% 能正确辨认一套 8 字母系列图标, 而关闭系统时, 只有 16.8%. 作者还提到, 激活视网膜下植入物技术也在进展. 尽管人工视 网膜技术非常复杂, 耗时漫长且费用�... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5366610 Tue, 01 Nov 2011 04:00:00 +0100 5366610 http://www.medworm.com/index.php?rid=5366607&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011009055%2Fabstract%3Frss%3Dyes (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5366607 Tue, 01 Nov 2011 04:00:00 +0100 5366607 http://www.medworm.com/index.php?rid=5650880&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007445%2Fabstract%3Frss%3Dyes Objective: To report the spectrum of iris lesions based on patient age at presentation. Design: Retrospective, nonrandomized, single-center case series. Participants: We included 3680 iris tumors in 3451 patients. Methods: Chart review. Main Outcome Measures: Diagnostic category based on age. Results: The mean age at presentation was 48 years and there were 449 (12%) tumors in children (≤20 years), 788 (21%) in young adults (21–40 years), 1308 (36%) in mid adults (41–60 years), and 1135 (31%) in senior adults (>60 years). Of 3680 tumors, the diagnostic category was cystic (n = 768; 21%) or solid (n = 2912; 79%). The cystic tumors originated from iris pigment epithelium (IPE; n = 672; 18%) or iris stroma (n = 96; 3%). The solid tumors included melanocytic (n = 2510; 68%) an... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650880 Mon, 31 Oct 2011 04:00:00 +0100 5650880 http://www.medworm.com/index.php?rid=5650879&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007457%2Fabstract%3Frss%3Dyes Conclusions: The abducens nerve is present on the affected side in type 2 Duane's retraction syndrome. Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650879 Mon, 31 Oct 2011 04:00:00 +0100 5650879 http://www.medworm.com/index.php?rid=5650878&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007299%2Fabstract%3Frss%3Dyes Conclusions: Strabismus surgery using adjustable sutures was associated with improved short-term ocular alignment compared with strabismus surgery without the use of adjustable sutures. Adjustable sutures were most beneficial for patients undergoing reoperations for childhood strabismus. Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650878 Mon, 31 Oct 2011 04:00:00 +0100 5650878 http://www.medworm.com/index.php?rid=5650872&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006919%2Fabstract%3Frss%3Dyes Objective: To estimate the prevalence of blindness in children in Vietnam and to assess the major causes. Design: A population-based study sampled children from 16 provinces across Vietnam. The second study examined children attending all blind schools in Vietnam. Participants: In 16 provinces, 28 800 children aged 0-15 were sampled. In 28 blind schools, 569 children aged 0-15 were examined. Intervention: In children not seeing well according to the parents, presenting visual acuity (PVA) was assessed. If PVA was (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650872 Mon, 31 Oct 2011 04:00:00 +0100 5650872 http://www.medworm.com/index.php?rid=5650869&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007470%2Fabstract%3Frss%3Dyes Purpose: To investigate the relationship of smoking to choroidal neovascularization (CNV) secondary to presumed ocular histoplasmosis syndrome (POHS). Design: Retrospective, case-control study. Participants: A total of 568 patients 18 to 50 years of age, 142 of whom were diagnosed with CNV secondary to POHS in a private retina practice between July 1, 2000, and August 1, 2010. Four hundred twenty-six were controls selected from a private comprehensive ophthalmology practice at the same location. Methods: A retrospective medical record review was performed for all participants. Age, gender, zip code, CNV diagnosis date, insurance status, and smoking status at CNV diagnosis date were collected first for the POHS patients. For each of these 142 patients, 3 randomly selected comprehensi... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650869 Mon, 31 Oct 2011 04:00:00 +0100 5650869 http://www.medworm.com/index.php?rid=5650862&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007809%2Fabstract%3Frss%3Dyes Conclusions: This study identifies a novel association between ED and prior OAG. Financial Disclosure(s): The authors have no proprietary or commercial interest in any of the materials discussed in this article. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650862 Mon, 31 Oct 2011 04:00:00 +0100 5650862 http://www.medworm.com/index.php?rid=5650861&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007585%2Fabstract%3Frss%3Dyes Purpose: To determine the immediate changes in intraocular pressure (IOP) after laser peripheral iridotomy in primary angle-closure suspects. Design: Prospective, randomized controlled trial (split-body design). Participants: Seven hundred thirty-four Chinese people 50 to 70 years of age. Methods: Primary angle-closure suspects underwent iridotomy using a neodymium:yttrium–aluminum–garnet laser in 1 randomly selected eye, with the fellow eye serving as a control. Intraocular pressure was measured using Goldmann applanation tonometry before treatment and 1 hour and 2 weeks after treatment. Total energy used and complications were recorded. Risk factors for IOP rise after laser peripheral iridotomy were investigated. Main Outcome Measures: Intraocular pressure. Results: The pr... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650861 Mon, 31 Oct 2011 04:00:00 +0100 5650861 http://www.medworm.com/index.php?rid=5650854&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006956%2Fabstract%3Frss%3Dyes Purpose: To ascertain the effects of aging on corneal morphology and to illustrate the morphologic diversity of the different layers in the normal cornea as seen by in vivo confocal microscopy (IVCM). Design: Observational cross-sectional study. Participants: A total of 150 healthy subjects, evenly distributed over 5 age categories, comprising 75 men and 75 women. Methods: Both transparent corneas (n = 300) of all subjects were examined in duplicate by white light IVCM (Confoscan 4, NIDEK Technologies, Albignasego, Padova, Italy). After reviewing the IVCM examinations for morphologic variations of the corneal layers, we selected the 8 most common features to illustrate the morphologic diversity. Subsequently, all 600 IVCM examinations were assessed for the presence of these features... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650854 Mon, 31 Oct 2011 04:00:00 +0100 5650854 http://www.medworm.com/index.php?rid=5650851&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006920%2Fabstract%3Frss%3Dyes This study describes the degree of burden and the prevalence of depression among individuals caring for legally blind patients. To the best of our knowledge, no prior studies in the ophthalmic literature have reported this relationship. Design: Clinic-based, cross-sectional study. Participants: We included 522 individuals in Rampur, India, providing care to their close family relatives who were legally blind. Visual acuities varied from 20/200 in the best eye, to no light perception (NLP) in each eye. Methods: Several surveys were completed by the caregivers of patients whose sole impairment was visual, allowing us to quantitatively and selectively assess burden and depression among caregivers of blind patients. Main Outcome Measures: The Burden Index of Caregivers (BIC) was used t... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650851 Mon, 31 Oct 2011 04:00:00 +0100 5650851 http://www.medworm.com/index.php?rid=5460209&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011008852%2Fabstract%3Frss%3Dyes Conclusions: Repair of blepharoptosis and upper eyelid dermatochalasis provides significant improvement in vision, peripheral vision, and quality of life activities. Preoperative indicators of improvement include margin reflex distance 1 (MRD1) of 2 mm or less, superior visual field loss of at least 12 degrees or 24%, down-gaze ptosis impairing reading and other close-work activities, a chin-up backward head tilt due to visual axis obscuration, symptoms of discomfort or eye strain due to droopy lids, central visual interference due to upper eyelid position, and patient self-reported functional impairment.Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5460209 Mon, 24 Oct 2011 04:00:00 +0100 5460209 http://www.medworm.com/index.php?rid=5460203&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011004684%2Fabstract%3Frss%3Dyes Conclusions: Ocular melanocytosis can be sectoral (partial), affecting only a mean of 5 to 6 clock hours of the uvea and can manifest melanoma within the melanocytosis region. There were no specific features of melanocytosis statistically related to the presence of melanoma.Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5460203 Mon, 24 Oct 2011 04:00:00 +0100 5460203 http://www.medworm.com/index.php?rid=5562554&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006877%2Fabstract%3Frss%3Dyes Objective: To confirm the advantages of the enhanced depth imaging (EDI) mode over the standard mode of the Heidelberg Spectralis spectral domain optical coherence tomography (SD-OCT) for imaging of the lamina cribrosa, and to compare laminar thicknesses of various glaucoma types with or without disc hemorrhage in a similar state of visual field loss. Design: Cross-sectional, case-control design. Participants: We included 137 glaucoma patients and 49 healthy controls. Methods: Optic nerve head B-scans were obtained by both the standard and EDI modes of the Spectralis OCT. Laminar thickness was measured at the center of mid-superior, central, and mid-inferior horizontal B-scans. Laminar thickness in patients with normal tension glaucoma (NTG) was compared with that in patients with p... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562554 Thu, 20 Oct 2011 04:00:00 +0100 5562554 http://www.medworm.com/index.php?rid=5562559&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007287%2Fabstract%3Frss%3Dyes Conclusions: Patients with idiopathic diffuse or nodular scleritis with a low degree of scleral inflammation or without ocular complications may respond to NSAIDs. Patients with idiopathic diffuse or nodular scleritis with a high degree of scleral inflammation may respond to SAIDs. Patients with diffuse or nodular scleritis with associated systemic disease may respond to IMT or BRMs. Patients with necrotizing scleritis may respond to IMT, mainly alkylating agents. Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562559 Wed, 19 Oct 2011 04:00:00 +0100 5562559 http://www.medworm.com/index.php?rid=5650856&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006865%2Fabstract%3Frss%3Dyes Conclusions: Endothelial cell migration after Descemet's stripping procedure without insertion of endothelial graft can occur, resulting from host endothelial cell repopulation with corneal clearing and improved visual acuity. Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650856 Mon, 10 Oct 2011 04:00:00 +0100 5650856 http://www.medworm.com/index.php?rid=5562573&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006142%2Fabstract%3Frss%3Dyes Objective: The purpose of this study is to investigate whether children with congenital esotropia (CET) are more likely than controls to develop mental illness by early adulthood. Design: Retrospective, population-based cohort. Participants: Children (aged (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562573 Mon, 10 Oct 2011 04:00:00 +0100 5562573 http://www.medworm.com/index.php?rid=5562557&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006257%2Fabstract%3Frss%3Dyes Purpose: To compare the effect of ab interno trabeculectomy with trabeculectomy. Design: Retrospective, cohort study. Participants: A total of 115 patients who underwent ab interno trabeculectomy (study group) compared with 102 patients who underwent trabeculectomy with intraoperative mitomycin as an initial surgical procedure (trabeculectomy group). Inclusion criteria were open-angle glaucoma, age ≥40 years, and uncontrolled on maximally tolerated medical therapy. Exclusion criterion was concurrent surgery. Methods: Clinical variables were collected from patient medical records. Main Outcome Measures: Intraocular pressure (IOP) and Cox proportional hazard ratio (HR) and Kaplan–Meier survival analyses with failure defined as IOP >21 mmHg or less than 20% reduction below baseli... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562557 Mon, 10 Oct 2011 04:00:00 +0100 5562557 http://www.medworm.com/index.php?rid=5562556&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011005616%2Fabstract%3Frss%3Dyes Conclusions: In this mainly white cohort from the United States, increasing age and female gender were significant risk factors for EG or EGS; however, Scandinavian heritage was not. Living in the middle or southern regions of the United States relative to living in the northern region was associated with a reduced risk of EG or EGS. Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562556 Mon, 10 Oct 2011 04:00:00 +0100 5562556 http://www.medworm.com/index.php?rid=5650877&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007330%2Fabstract%3Frss%3Dyes Conclusions: Acquired lower eyelid epiblepharon is one of the clinical features of patients with TAO. The association between lower eyelid retraction and acquired epiblepharon may lead to a better understanding of the cause of acquired epiblepharon in patients with TAO. Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650877 Fri, 07 Oct 2011 04:00:00 +0100 5650877 http://www.medworm.com/index.php?rid=5650875&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006336%2Fabstract%3Frss%3Dyes Conclusions: Bilateral ptosis cases with documented Hering's dependency yield better results when both eyes are operated in the same session, rather than delaying surgery for the second eyelid. Ocular dominance probably has a significant impact on Hering's dependency and postoperative outcome after unilateral operations. Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650875 Fri, 07 Oct 2011 04:00:00 +0100 5650875 http://www.medworm.com/index.php?rid=5562566&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006269%2Fabstract%3Frss%3Dyes Conclusions: During pharmacologic accommodation, the ICL and the crystalline lens came closer as the ICL was pushed backward by the iris as a result of pupillary constriction. Simultaneously, the anterior surface of the crystalline lens became more convex and moved forward. Reduction of the distances at peripheral sulci was not as obvious as at the center. Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562566 Fri, 07 Oct 2011 04:00:00 +0100 5562566 http://www.medworm.com/index.php?rid=5562555&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007366%2Fabstract%3Frss%3Dyes Conclusions: We demonstrate progressive tilting of the ONH, which was observed with development/enlargement of PPA in children who exhibited myopic shift. These findings suggest that tilted disc, as well as PPA, may be an acquired feature in myopic eyes, arising from scleral stretching. Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562555 Fri, 07 Oct 2011 04:00:00 +0100 5562555 http://www.medworm.com/index.php?rid=5562553&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS016164201100666X%2Fabstract%3Frss%3Dyes Conclusions: Enhanced depth imaging OCT was able to visualize a wide variety of deep ONC structures in glaucoma patients and may be helpful in detecting, conceptualizing, and understanding basic and complicated in vivo anatomic and pathologic features of the ONC in glaucoma. Financial Disclosure(s): Proprietary or commercial disclosure may be found after the references. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562553 Fri, 07 Oct 2011 04:00:00 +0100 5562553 http://www.medworm.com/index.php?rid=5562580&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006154%2Fabstract%3Frss%3Dyes Conclusions: One or 2 cycles of IAC can be sufficient for selected eyes with group C or D retinoblastoma, with remarkable tumor control. Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562580 Wed, 05 Oct 2011 04:00:00 +0100 5562580 http://www.medworm.com/index.php?rid=5562563&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006245%2Fabstract%3Frss%3Dyes We report the frequency and effectiveness of patient-initiated epilation and its relationship to corneal opacity. Design: Cross-sectional baseline data of individuals recruited to 2 randomized, clinical trials. Participants: We included 2556 individuals (4310 eyes) with previously unoperated TT in ≥1 eye. Methods: A single ophthalmologist examined all participants for signs of trachoma using WHO grading systems with additional assessment of entropion grading, location and number of trichiatic lashes, and evidence of epilation. A questionnaire enquired about epilation practices. Main Outcome Measures: The association between epilation and degree of corneal opacity. Epilation practices of TT patients. Results: Central corneal scarring was present in 1436 (33%) eyes. Entropion was... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562563 Wed, 05 Oct 2011 04:00:00 +0100 5562563 http://www.medworm.com/index.php?rid=5650874&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007317%2Fabstract%3Frss%3Dyes Conclusions: Choroidal abnormalities appearing as bright patchy nodules detected by NIR imaging frequently occurred in NF1 patients. The present study shows that NIR examination to detect choroidal involvement should be considered as a new diagnostic criterion for NF1. Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650874 Mon, 03 Oct 2011 04:00:00 +0100 5650874 http://www.medworm.com/index.php?rid=5650871&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006853%2Fabstract%3Frss%3Dyes Conclusions: Atropine 0.01% has minimal side effects compared with atropine at 0.1% and 0.5%, and retains comparable efficacy in controlling myopia progression. Financial Disclosure(s): The author(s) have no proprietary or commercial interest in any materials discussed in this article. (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5650871 Mon, 03 Oct 2011 04:00:00 +0100 5650871 http://www.medworm.com/index.php?rid=5562572&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011005677%2Fabstract%3Frss%3Dyes Purpose: To determine the prevalence of and factors associated with amblyopia in a sample of Australian preschool children. Design: Population-based, cross-sectional study. Participants: The Sydney Paediatric Eye Disease Study examined 2461 (73.8% participation) children aged between 6 and 72 months from 2007 to 2009. Methods: Visual acuity (VA) was assessed in children aged ≥30 months using the Electronic Visual Acuity system, and a subset using the logarithm of the minimum angle of resolution chart. Amblyopia was categorized into unilateral and bilateral subtypes: Unilateral amblyopia was defined as a 2-line difference in reduced VA between the 2 eyes, in addition to strabismus, anisometropia, and/or visual axis obstruction; bilateral amblyopia was defined as bilateral reduced V... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562572 Mon, 03 Oct 2011 04:00:00 +0100 5562572 http://www.medworm.com/index.php?rid=5562558&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006671%2Fabstract%3Frss%3Dyes Objective: To evaluate the demographic characteristics, clinical features, ocular complications, and disease associations of patients with scleritis and episcleritis; as well as to delineate the risk factors for decreased vision in patients with scleritis. Design: Retrospective case series. Participants: Five hundred patients with scleritis and 85 patients with episcleritis. Methods: The electronic health records of 500 patients with scleritis and 85 patients with episcleritis seen at 2 tertiary referral centers were reviewed and their clinical features were studied. Main Outcome Measures: Clinical features (pain, scleral inflammation), ocular complications (decrease in vision, anterior uveitis, peripheral ulcerative keratitis, ocular hypertension), and disease associations. Resu... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5562558 Mon, 03 Oct 2011 04:00:00 +0100 5562558 http://www.medworm.com/index.php?rid=5276394&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011007305%2Fabstract%3Frss%3Dyes (Source: Ophthalmology) Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5276394 Sat, 01 Oct 2011 04:00:00 +0100 5276394 http://www.medworm.com/index.php?rid=5276393&cid=s_36642_30_f&fid=36642&url=http%3A%2F%2Fwww.ophsource.org%2Fperiodicals%2Fophtha%2Farticle%2FPIIS0161642011006695%2Fabstract%3Frss%3Dyes (SLS) is a neurocutaneous disorder inherited as an autosomal recessive trait, caused by mutations in the ALDH3A2 gene that encodes the enzyme fatty aldehyde dehydrogenase (FALDH). Patients with this disease show ichthiosys, mental retardation, and spasticity. Most of the patients present with photophobia, variable decrease in visual acuity (VA) and a typical macular dystrophy described as crystalline maculopathy. Necropsy material from the eye of a patient with SLS showed a significant increase in lipofuscin granules and a decrease in melanin and melanolipofuscin granules in the retinal pigment epithelium (RPE) in the macular area. These changes in the normal content of fluorophores of the RPE are clearly highlighted by fundus autofluorescence (FAF) imaging. Recently Van der Veen et al de... Ophthalmology journals http://www.medworm.com/rss/comments.php?id=5276393 Sat, 01 Oct 2011 04:00:00 +0100 5276393