MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Oral Diseases' source. Wed, 08 Feb 2012 15:44:38 +0100 http://www.medworm.com/index.php?rid=5660457&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2012.01914.x Conclusions:  Children and preadolescents with poor emotional well‐being are more sensitive to the impacts of OH and its effects on OWB.© 2012 John Wiley & Sons A/S (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5660457 Sun, 05 Feb 2012 20:02:03 +0100 5660457 http://www.medworm.com/index.php?rid=5648883&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2012.01913.x Conclusions:  In the static or dynamic flow system, platelets adhered to S. sanguinis or P. gingivalis. However, if S. sanguinis was mixed with P. gingivalis, the aggregation magnitude (%) was significantly reduced.© 2012 John Wiley & Sons A/S (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5648883 Thu, 02 Feb 2012 20:10:35 +0100 5648883 http://www.medworm.com/index.php?rid=5648884&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2012.01912.x Conclusion:  The statistical approach applying PCA to our data may contribute to the better understanding of factors playing role in the development of bisphosphonate‐induced ONJ.© 2012 John Wiley & Sons A/S (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5648884 Tue, 31 Jan 2012 05:00:00 +0100 5648884 http://www.medworm.com/index.php?rid=5629445&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2012.01911.x AbstractNon‐exposed bisphosphonate related osteonecrosis of the jaw (BRONJ) is a newly reported complication arising from bisphosphonate therapy which presents with atypical symptoms and no apparent mucosal fenestration or exposure of necrotic bone. The clinical observation of the presence of necrotic bone underneath normal epithelial coverage was not conclusive for the diagnosis of BRONJ based on current guidelines established by the American Association of Oral and Maxillofacial Surgeons (AAOMS) and the American Society for Bone and Mineral Research (ASBMR), which specify the presence of clinically exposed necrotic bone for more than 8 weeks. Hence, the purpose of this review is to critically assess the current guidelines for diagnosis and management of BRONJ and propose a modified sta... Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5629445 Thu, 26 Jan 2012 20:29:51 +0100 5629445 http://www.medworm.com/index.php?rid=5629450&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2012.01897.x Conclusion:  Both PPP and PRP promote gingival fibroblast migration and proliferation in vitro, without differences between preparations obtained from autologous and allogenic sources. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5629450 Wed, 25 Jan 2012 05:00:00 +0100 5629450 http://www.medworm.com/index.php?rid=5629448&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2012.01901.x (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5629448 Wed, 25 Jan 2012 05:00:00 +0100 5629448 http://www.medworm.com/index.php?rid=5620704&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2012.01910.x Conclusion:  A high prevalence of actinic AC was observed. Special attention should be given to individuals chronically exposed to UV radiation, with the institution of educational, preventive and curative measures.© 2012 John Wiley & Sons A/S (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5620704 Mon, 23 Jan 2012 20:09:15 +0100 5620704 http://www.medworm.com/index.php?rid=5609713&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2012.01902.x Conclusions:  In STZ‐treated mice, significant reduction in salivary flow rate was observed without any concomitant modification in AQP5 expression and localization. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5609713 Wed, 18 Jan 2012 05:00:00 +0100 5609713 http://www.medworm.com/index.php?rid=5598478&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2009.01555.x Oral Diseases (2012) 18, 214–216The use of eponyms has long been contentious, but many remain in common use, as discussed elsewhere (Editorial: Oral Diseases. 2009: 15; 185). The use of eponyms in diseases of the head and neck is found mainly in specialties dealing with medically compromised individuals (paediatric dentistry, special care dentistry, oral and maxillofacial medicine, oral and maxillofacial pathology and oral, oral and maxillofacial radiology and maxillofacial surgery) and particularly by hospital‐centred practitioners. This series has selected some of the more recognized relevant eponymous conditions and presents them alphabetically. The information is based largely on data available from MEDLINE and a number of internet websites as noted below: the authors would welcome... Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5598478 Tue, 17 Jan 2012 21:04:17 +0100 5598478 http://www.medworm.com/index.php?rid=5598477&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2012.01909.x Conclusions:  Altered aquaporin‐5 distribution in submandibular acinar cells from IQI/JIC, non‐obese diabetic, and r1ΔT/r2n mice with a focus score ≥ 1 appears to be concomitant to the presence of inflammatory infiltrates and acinar destruction.© 2012 John Wiley & Sons A/S (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5598477 Tue, 17 Jan 2012 21:02:11 +0100 5598477 http://www.medworm.com/index.php?rid=5582944&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2012.01900.x (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5582944 Wed, 11 Jan 2012 05:00:00 +0100 5582944 http://www.medworm.com/index.php?rid=5582943&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2012.01904.x Conclusions:  Chitinase was highly expressed in rat parotid acinar cells from diabetic mice compared with non‐diabetic and control mice. Increased chitinase expression and enzyme activity may characterize the autoimmune diabetes in mice; however, further investigation is required to assess its use as a biomarker of xerostomia in humans.© 2012 John Wiley & Sons A/S (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5582943 Tue, 10 Jan 2012 05:00:00 +0100 5582943 http://www.medworm.com/index.php?rid=5582942&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2012.01905.x Conclusions:  These results suggest that DR5 is a potential molecular target for PEITC‐induced apoptosis in oral cancer via p38 MAPK.© 2012 John Wiley & Sons A/S (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5582942 Tue, 10 Jan 2012 05:00:00 +0100 5582942 http://www.medworm.com/index.php?rid=5582941&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2012.01906.x Conclusions:  Humoral factors released from hPDLSCs seemed to modulate the differentiation of hABCs, and the osteoclastogenic, osteogenic, and adipogenic differentiation of hABCs were all inhibited suggesting the potential role of hPDLSCs in the maintenance of the alveolar bone.© 2012 John Wiley & Sons A/S (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5582941 Tue, 10 Jan 2012 05:00:00 +0100 5582941 http://www.medworm.com/index.php?rid=5582940&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2012.01907.x Conclusions:  Complementary treatment with Carnoy’s solution and peripheral ostectomy appear to provide efficient treatment for keratocystic odontogenic tumors. Complications originating from the use of the solution are less frequent and less serious than complications associated with cryotherapy. Neuropathy seems to be related to direct contact between the solution and the epineurium.© 2012 John Wiley & Sons A/S (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5582940 Tue, 10 Jan 2012 05:00:00 +0100 5582940 http://www.medworm.com/index.php?rid=5582939&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2012.01908.x Conclusions:  There were significant differences in the prevalence and proportions of specific microbial taxa between HIV‐ and HIV+ individuals. The root canal microbiota may represent a reservoir of important oral and medical pathogens, mainly in HIV+ individuals.© 2012 John Wiley & Sons A/S (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5582939 Sun, 01 Jan 2012 05:00:00 +0100 5582939 http://www.medworm.com/index.php?rid=5572631&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2012.01903.x (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5572631 Sun, 01 Jan 2012 05:00:00 +0100 5572631 http://www.medworm.com/index.php?rid=5552817&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01898.x AbstractGaucher disease is a systemic lysosomal storage disorder with a high prevalence among Ashkenazi Jews. It is caused by an inherited deficiency of the lysosomal enzyme glucocerebrosidase. Common signs and symptoms include hepatosplenomegaly, anemia, thrombocytopenia, and skeletal involvement. Oral and dental manifestations are less commonly seen. These manifestations are often asymptomatic, although they may be detected by routine dental x‐rays. There are several case reports and a few larger series published describing patients with Gaucher disease who have mandibulo‐maxillofacial involvement. This review aims to examine the oral manifestations observed in Gaucher disease and to suggest practical guidelines for dealing with these often worrisome signs. Among the critical issues ... Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5552817 Sat, 31 Dec 2011 09:58:02 +0100 5552817 http://www.medworm.com/index.php?rid=5544895&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01902.x Conclusion:  In STZ‐treated mice, significant reduction in salivary flow rate was observed without any concomitant modification in AQP5 expression and localization.© 2011 John Wiley & Sons A/S (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5544895 Wed, 28 Dec 2011 11:42:25 +0100 5544895 http://www.medworm.com/index.php?rid=5629449&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01900.x (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5629449 Wed, 28 Dec 2011 05:00:00 +0100 5629449 http://www.medworm.com/index.php?rid=5552819&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01900.x (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5552819 Wed, 28 Dec 2011 05:00:00 +0100 5552819 http://www.medworm.com/index.php?rid=5552818&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01897.x Conclusion:  Both PPP and PRP promote gingival fibroblast migration and proliferation in vitro, without differences between preparations obtained from autologous and allogenic sources.© 2011 John Wiley & Sons A/S (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5552818 Wed, 28 Dec 2011 05:00:00 +0100 5552818 http://www.medworm.com/index.php?rid=5544896&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01901.x (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5544896 Wed, 28 Dec 2011 05:00:00 +0100 5544896 http://www.medworm.com/index.php?rid=5538478&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01899.x AbstractPemphigus vulgaris (PV) is the most common type of pemphigus. PV pathogenesis is still debated and treatment remains challenging. We investigated five controversial topics: (1) What are the target antigens in PV? (2) Do desmogleins adequately address PV pathophysiology? (3) How does acantholysis occur in PV? (4) Is PV still a lethal disease? (5) What is the role of Rituximab (RTX) in PV treatment? Results from extensive literature searches, suggested the following: (1) Target antigens of PV include a variety of molecules and receptors that are not physically compartmentalized within the epidermis (2) PV is caused by a variety of autoantibodies to keratinocyte self antigens, which concur to cause blistering by acting synergistically (3) The concept of apoptolysis distinguishes the u... Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5538478 Sun, 25 Dec 2011 08:32:35 +0100 5538478 http://www.medworm.com/index.php?rid=5525656&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2009.01554.x Oral Diseases (2012) 18, 107–108The use of eponyms has long been contentious, but many remain in common use, as discussed elsewhere (Editorial: Oral Diseases. 2009: 15; 185). The use of eponyms in diseases of the head and neck is found mainly in specialties dealing with medically compromised individuals (paediatric dentistry, special care dentistry, oral and maxillofacial medicine, oral and maxillofacial pathology, oral and maxillofacial radiology and oral and maxillofacial surgery) and particularly by hospital‐centred practitioners. This series has selected some of the more recognized relevant eponymous conditions and presents them alphabetically. The information is based largely on data available from MEDLINE and a number of internet websites as noted below: the authors would welcome... Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5525656 Thu, 22 Dec 2011 08:36:31 +0100 5525656 http://www.medworm.com/index.php?rid=5525649&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01896.x Conclusion:  This study indicates that VicRK and CovR regulate functions which influence bacterial susceptibility to phagocytosis, suggesting a novel role for these systems in the virulence of S. mutans.© 2011 John Wiley & Sons A/S (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5525649 Thu, 22 Dec 2011 08:34:55 +0100 5525649 http://www.medworm.com/index.php?rid=5609715&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01894.x Conclusions:  This study has identified several major CNAs in oral cancer genomes and indicated that this correlates with over expression of the ISG15, WNT11, and Nestin genes. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5609715 Wed, 21 Dec 2011 05:00:00 +0100 5609715 http://www.medworm.com/index.php?rid=5609714&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01895.x Conclusions:  Including the p53 ELAV‐like protein‐binding site in transgene cassettes may enhance therapeutic vectors intended for use with salivary glands. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5609714 Wed, 21 Dec 2011 05:00:00 +0100 5609714 http://www.medworm.com/index.php?rid=5525651&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01894.x Conclusions:  This study has identified several major CNAs in oral cancer genomes and indicated that this correlates with over expression of the ISG15, WNT11 and Nestin genes.© 2011 John Wiley & Sons A/S (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5525651 Wed, 21 Dec 2011 05:00:00 +0100 5525651 http://www.medworm.com/index.php?rid=5525650&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01895.x Conclusion:  Including the p53 ELAV‐like protein binding site in transgene cassettes may enhance therapeutic vectors intended for use with salivary glands.Published 2011. This article is a US Government work and is in the public domain in the USA (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5525650 Wed, 21 Dec 2011 05:00:00 +0100 5525650 http://www.medworm.com/index.php?rid=5525653&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01892.x This article reviews the rapidly growing evidence that oral HPV infection contributes to risk of oral squamous cell carcinoma. It also reports the first nationally‐representative estimates of oral HPV prevalence in the United States adult population. An estimated 7.3% (95% CI: 6.0, 8.9) of the U.S. population had one or more oral HPV types detected in oral rinse; 3.1% (95%CI: 2.4, 3.9) of the U.S. population had one or more oncogenic HPV types. A substantial excess risk of HPV infection in males is not explained by education, smoking, age of sexual debut or number of lifetime sex partners. Based on the published finding from a case‐control study, where there was an odds ratio of 2.6 (95% CI: 1.5, 4.2) for the association of head and neck cancer oncogenic oral HPV infection, the estimat... Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5525653 Mon, 19 Dec 2011 05:00:00 +0100 5525653 http://www.medworm.com/index.php?rid=5525652&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01893.x Conclusions:  These findings indicate that the H‐SC diet induced a transient increase in alveolar bone remodeling, which is followed by ABL characteristic of moderate periodontitis.© 2011 John Wiley & Sons A/S (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5525652 Mon, 19 Dec 2011 05:00:00 +0100 5525652 http://www.medworm.com/index.php?rid=5629446&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01890.x This article reviews the aetiopathogenesis of halitosis (oral malodour) and management. Halitosis is any disagreeable breath odour. In most patients, the odour originates from the oral cavity. In some patients, it has an extra‐oral aetiology and, in a few, metabolic anomalies are responsible. In other patients complaining of malodour, this is imagined rather than real. Volatile sulphur compounds (VSCs) and other elements appear largely responsible for the malodour. Predisposing factors include poor oral hygiene, hyposalivation, dental appliances, gingival and periodontal disease and mucosal disease. The first step in assessment is objective measurement to determine whether malodour is present. If present, the oral or extra‐oral origin should be determined, because the latter requires m... Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5629446 Thu, 15 Dec 2011 05:00:00 +0100 5629446 http://www.medworm.com/index.php?rid=5505827&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01890.x AbstractThis paper reviews the aetiopathogenesis of halitosis (oral malodour), and management. Halitosis is any disagreeable breath odour. In most patients the odour originates from the oral cavity. In some patients, it has an extra‐oral aetiology and, in a few, metabolic anomalies are responsible. In other patients complaining of malodour, this is imagined rather than real.Volatile sulphur compounds (VSCs) and other elements appear largely responsible for the malodour. Predisposing factors include poor oral hygiene, hyposalivation, dental appliances, gingival and periodontal disease, and mucosal disease.The first step in assessment is objective measurement to determine whether malodour is present. If present, the oral or extra‐oral origin should be determined, since the latter require... Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5505827 Thu, 15 Dec 2011 05:00:00 +0100 5505827 http://www.medworm.com/index.php?rid=5505828&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01889.x Conclusions:  These data confirm that the oral cavity is an important site of S. aureus colonization and demonstrate that conditions modifying the oral environment, as the presence of periodontitis and of fixed prosthetic restorations promote S. aureus carriage, and may favor the spread of more pathogenic strains.© 2011 John Wiley & Sons A/S (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5505828 Tue, 13 Dec 2011 05:00:00 +0100 5505828 http://www.medworm.com/index.php?rid=5560896&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01887.x Conclusion: MBL2 gene polymorphism is associated with caries experience in Polish children, but the direction of this association seems to be opposite in primary and permanent dentition. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5560896 Fri, 09 Dec 2011 05:00:00 +0100 5560896 http://www.medworm.com/index.php?rid=5487681&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01887.x Conclusion MBL2 gene polymorphism is associated with caries experience in Polish children, but the direction of this association seems to be opposite in primary and permanent dentition.© 2011 John Wiley & Sons A/S (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5487681 Fri, 09 Dec 2011 05:00:00 +0100 5487681 http://www.medworm.com/index.php?rid=5552820&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01885.x Conclusion:  Although local expression of soluble TACI‐Fc reduced inflammation and immunoglobulin levels in the SG, further research will have to prove whether dual blockade of APRIL and BAFF by TACI‐Fc can provide a satisfying treatment for the clinical symptoms of patients. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5552820 Mon, 05 Dec 2011 05:00:00 +0100 5552820 http://www.medworm.com/index.php?rid=5477121&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01886.x Conclusion:  These results suggest that Th17 cells may aggravate the process of orthodontically‐induced inflammatory root resorption.© 2011 John Wiley & Sons A/S (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5477121 Mon, 05 Dec 2011 05:00:00 +0100 5477121 http://www.medworm.com/index.php?rid=5441710&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01883.x AbstractThe aim of this article is to review the clinical, pathophysiological and therapeutic aspects of traumatically induced trigeminal nerve pain. We introduce a new and, in our view, more accurate terminology: peripheral painful traumatic trigeminal neuropathy (PPTTN) to define this patient group. The proposed pathophysiology of PPTTN is largely based on studies in spinal nerve injury models. However trigeminal nerve injury studies have shown some subtle differences response to physical and inflammatory insults and these are discussed. The treatment of painful neuropathies is difficult and carries a poor prognosis. Based on the available literature on efficacy and side effects we propose a treatment algorithm for traumatic trigeminal neuropathies. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5441710 Tue, 22 Nov 2011 05:00:00 +0100 5441710 http://www.medworm.com/index.php?rid=5495226&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01878.x Conclusion:  These data suggest that bFGF inhibits osteogenic differentiation of SHED via ERK1/2 pathway. Blockade ERK1/2 signaling by small molecular inhibitor treatment improves bone formation of SHED after bFGF treatment. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5495226 Mon, 21 Nov 2011 05:00:00 +0100 5495226 http://www.medworm.com/index.php?rid=5495224&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01881.x Conclusion:  Subjects with osteoporosis (OPR) presented with greater CAL than the subjects with normal BMDa, which suggests a greater severity of periodontitis. Subjects with OPR had greater GR than the subjects with normal BMDa. Subjects with osteopenia and subjects with normal BMDa did not differ in CAL, which might suggest that the early diagnosis of reduced BMDa, prior to the establishment of a significant negative impact on the periodontal tissues, might be important. Smoking and menopausal status did not alter these associations. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5495224 Sat, 19 Nov 2011 05:00:00 +0100 5495224 http://www.medworm.com/index.php?rid=5432278&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01881.x Conclusion:  Subjects with osteoporosis presented with greater clinical attachment loss than the subjects with normal areal bone mineral density, which suggests a greater severity of periodontitis. Subjects with osteoporosis had greater gingival recession than the subjects with normal areal bone mineral density. Subjects with osteopenia and subjects with normal areal bone mineral density did not differ in clinical attachment loss, which might suggest that the early diagnosis of reduced areal bone mineral density, prior to the establishment of a significant negative impact on the periodontal tissues, might be important. Smoking and menopausal status did not alter these associations. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5432278 Sat, 19 Nov 2011 05:00:00 +0100 5432278 http://www.medworm.com/index.php?rid=5432277&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01882.x Conclusions:  Our results suggest that the combination of IL‐8 gene polymorphisms and environmental carcinogens might be highly related to the risk of oral cancer. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5432277 Sat, 19 Nov 2011 05:00:00 +0100 5432277 http://www.medworm.com/index.php?rid=5495227&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01880.x Conclusion:  The combination of the periodontal therapy and antilipemic treatment may provide beneficial effects on the metabolic and inflammatory control of hyperlipidemia. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5495227 Tue, 15 Nov 2011 05:00:00 +0100 5495227 http://www.medworm.com/index.php?rid=5495225&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01879.x Conclusion:  The Portuguese version of the XI can be considered a reliable and valid instrument to measure patients’ xerostomia symptoms. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5495225 Tue, 15 Nov 2011 05:00:00 +0100 5495225 http://www.medworm.com/index.php?rid=5409221&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01879.x Conclusion:  The Portuguese version of the XI (XI‐PL) can be considered a reliable and valid instrument to measure patients xerostomia symptoms. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5409221 Tue, 15 Nov 2011 05:00:00 +0100 5409221 http://www.medworm.com/index.php?rid=5388251&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01877.x Conclusions:  While granulocyte and monocyte phagocytic intensities are similar in Down and non‐DS individuals, phagocytic intensity was associated with more AL in DS than non‐DS individuals. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5388251 Tue, 08 Nov 2011 05:00:00 +0100 5388251 http://www.medworm.com/index.php?rid=5505826&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01891.x Conclusions:  Smoking, an established and common risk factor of periodontitis, was assessed as a possible influencing factor for salivary histamine. Most interestingly, salivary histamine differed highly significantly between smoking and non‐smoking periodontitis patients. Our results suggest a possible involvement of histamine in tobacco‐exacerbated periodontal disease, but do not suggest salivary histamine as a reliable diagnostic marker for periodontitis.© 2011 John Wiley & Sons A/S (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5505826 Tue, 01 Nov 2011 04:00:00 +0100 5505826 http://www.medworm.com/index.php?rid=5487680&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01888.x Conclusion  Knowledge of some similarities in patients’ profile could help OML making diagnosis process by either general physicians or dentists, especially those without extensive experience in the field of oral medicine.© 2011 John Wiley & Sons A/S (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5487680 Tue, 01 Nov 2011 04:00:00 +0100 5487680 http://www.medworm.com/index.php?rid=5477120&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01885.x Conclusion:  Although local expression of soluble TACI‐Fc reduced inflammation and immunoglobulin levels in the SG, further research will have to prove whether dual blockade of APRIL and BAFF by TACI‐Fc can provide a satisfying treatment for the clinical symptoms of patients.© 2011 John Wiley & Sons A/S (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5477120 Tue, 01 Nov 2011 04:00:00 +0100 5477120 http://www.medworm.com/index.php?rid=5441709&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01884.x AbstractBackground and objective: Alteration of salivary gland secretion is one of the consequences of diabetes. In a recent study on the submandibular gland of diabetic subjects, we found changed expression of statherin, a salivary protein of fundamental importance in preserving tooth integrity, whose reduction was related with the high incidence of oral diseases in diabetics. The goal of this report is to extend the study to human parotid gland and to compare the effects of diabetes on statherin expression with those previously described in submandibular gland.Materials and methods: Fragments of parotid glands obtained from diabetic and non‐diabetic patients were fixed, dehydrated, embedded in Epon Resin and processed for the immunogold histochemistry. The staining density was expresse... Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5441709 Tue, 01 Nov 2011 04:00:00 +0100 5441709 http://www.medworm.com/index.php?rid=5432276&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01878.x Conclusion:  These data suggest that bFGF inhibits osteogenic differentiation of SHED via ERK1/2 pathway. Blockade ERK1/2 signaling by small molecular inhibitor‐treatment improves bone formation of SHED after bFGF treatment. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5432276 Tue, 01 Nov 2011 04:00:00 +0100 5432276 http://www.medworm.com/index.php?rid=5409220&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01880.x Conclusion:  The combination of the periodontal therapy and anti‐lipemic treatment may provide beneficial effects on the metabolic and inflammatory control of hyperlipidaemia. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5409220 Tue, 01 Nov 2011 04:00:00 +0100 5409220 http://www.medworm.com/index.php?rid=5401206&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01875.x (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5401206 Tue, 01 Nov 2011 04:00:00 +0100 5401206 http://www.medworm.com/index.php?rid=5388250&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01876.x This article provides an overview the application of genomic technologies to oral health care and introduces issues that require consideration if we are to realize the full potential of genomics to enable the practice of personalized dental medicine. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5388250 Tue, 01 Nov 2011 04:00:00 +0100 5388250 http://www.medworm.com/index.php?rid=5361588&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01874.x Conclusions:  Although many chemical agents contained in oral hygiene products have proven in vitro activity against S. aureus, their clinical effectiveness and potential role as adjuncts or alternative therapies to conventional treatment remains to be confirmed by further high‐quality randomized controlled trials. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5361588 Tue, 01 Nov 2011 01:09:11 +0100 5361588 http://www.medworm.com/index.php?rid=5348555&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01873.x Conclusions:  Fluorides induce oxidative stress, resulting in apoptosis and activation of HUVECs, manifested by an elevated expression of ICAM‐1. The oxidative stress resulting from a stimulation by the highest NaF concentration triggers ICAM‐3 expression on the HUVECs’ surface. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5348555 Wed, 26 Oct 2011 19:48:39 +0100 5348555 http://www.medworm.com/index.php?rid=5336801&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01872.x Conclusions:  These findings indicate the possible use of interleukin‐10 single nucleotide polymorphisms as genetic markers in chronic periodontitis patients, and further emphasize the molecular differences between chronic periodontitis and aggressive periodontitis. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5336801 Sat, 22 Oct 2011 08:17:09 +0100 5336801 http://www.medworm.com/index.php?rid=5336803&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01870.x AbstractThe potential impact of stem cell technology on medical and dental practice is vast. Stem cell research will not only provide the foundation for future therapies, it will also reveal unique insights into basic disease mechanisms. Therefore, an understanding of stem cell technology will be necessary for clinicians in the future. Herein, we give a basic overview of stem cell biology and therapeutics for the practicing clinician. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5336803 Fri, 21 Oct 2011 04:00:00 +0100 5336803 http://www.medworm.com/index.php?rid=5336802&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01871.x Conclusion:  Growth differentiation factor 5 induced the expression of scleraxis and may enhance tendo/ligamentogenesis in human periodontal ligament‐derived cells. The expression of scleraxis was higher in STRO‐1 negative fraction, suggesting more differentiated state of the cells. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5336802 Fri, 21 Oct 2011 04:00:00 +0100 5336802 http://www.medworm.com/index.php?rid=5336804&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01869.x Conclusion:  These data indicate that miRNAs may be the novel candidate biomarkers for the implication of miRNAs in the pathogenesis of OLP. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5336804 Tue, 18 Oct 2011 04:00:00 +0100 5336804 http://www.medworm.com/index.php?rid=5315249&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01840.x Oral Diseases (2011) 17, 755–770Recurrent aphthous stomatitis (RAS) is the most common idiopathic intraoral ulcerative disease in the USA. Aphthae typically occur in apparently healthy individuals, although an association with certain systemic diseases has been reported. Despite the unclear etiopathogenesis, new drug trials are continuously conducted in an attempt to reduce pain and dysfunction. We investigated four controversial topics: (1) Is complex aphthosis a mild form of Behçet’s disease (BD)? (2) Is periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) syndrome a distinct medical entity? (3) Is RAS associated with other systemic diseases [e.g., celiac disease (CD) and B12 deficiency]? (4) Are there any new RAS treatments? Results from extensive literature searc... Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5315249 Sat, 15 Oct 2011 08:07:39 +0100 5315249 http://www.medworm.com/index.php?rid=5315248&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01859.x (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5315248 Sat, 15 Oct 2011 08:07:32 +0100 5315248 http://www.medworm.com/index.php?rid=5388253&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01866.x Conclusion:  Increased whole‐salivary output of Cl− and K+ in SjS may reflect release from apoptotic rests of acinar cells after secondary necrosis. Normal levels of salivary Na+, Mg2+, and − argue against concentration effect, deranged tubular function or cortisol (mineralocorticosteroid) effect as the cause for these findings. Increased salivary Ca2+ levels probably reflect leakage of plasma Ca2+ through the injured oral mucosa in SjS. In spite of disease‐associated stress, salivary cortisol, a stress biomarker, was not increased, suggesting insufficient hypothalamus–pituitary–adrenal (HPA) axis response and/or local consumption of cortisol by lymphocyte infiltrates. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5388253 Tue, 11 Oct 2011 04:00:00 +0100 5388253 http://www.medworm.com/index.php?rid=5388252&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01868.x Oral Diseases (2011)The aim of this study is to evaluate the oral colonization by Candida albicans in experimental murine immunosuppressed DBA/2 and treatment with probiotic bacteria. To achieve these objectives, 152 DBA/2‐immunosuppressed mice were orally inoculated with a suspension of C. albicans containing 108 viable yeast cells, the animals were treated with nystatin or with the probiotics (Lactobacillus acidophilus and Lactobacillus rhamnosus). Evaluations were performed by Candida count from oral mucosa swabbing. The oral mucosa colonization by C. albicans started at day 1 after inoculation, remained maximal from day 3 until day 7, and then decreased significantly. Probiotics reduced the C. albicans colonization significantly on the oral mucosa in comparison with the untreated ... Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5388252 Tue, 11 Oct 2011 04:00:00 +0100 5388252 http://www.medworm.com/index.php?rid=5305031&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01866.x Conclusion:  Increased whole salivary output of Cl¯ and K+ in SjS may reflect release from apoptotic rests of acinar cells after secondary necrosis. Normal levels of salivary Na+, Mg2+ and PO43‐ argue against concentration effect, deranged tubular function or cortisol (mineralocorticosteroid) effect as the cause for these findings. Increased salivary Ca2+ levels probably reflect leakage of plasma Ca2+ through the injured oral mucosa in SjS. In spite of disease‐associated stress, salivary cortisol, a stress biomarker, was not increased, suggesting insufficient hypothalamus‐pituitary‐adrenal (HPA) axis response and/or local consumption of cortisol by lymphocyte infiltrates. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5305031 Tue, 11 Oct 2011 04:00:00 +0100 5305031 http://www.medworm.com/index.php?rid=5305030&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01867.x SummaryInterleukin‐6 (IL‐6) is a pleomorphic cytokine involved in a number of physiological and pathological processes including response to trauma and infection and development and progression of inflammation and malignancy. IL‐6 is emerging as an important mediator and novel therapeutic target for chronic inflammatory diseases and cancer. The present paper reviews the available evidence regarding the association between IL‐6 and a range of oral diseases including infections (periodontal disease and endodontic infections), immunologically‐mediated disorders (oral lichen planus, Sjogren’s syndrome) and malignancy (oral cancer and pre‐cancer). The role of common genetic variants of IL‐6 in determining individual susceptibility to certain oral diseases, as well as novel thera... Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5305030 Tue, 11 Oct 2011 04:00:00 +0100 5305030 http://www.medworm.com/index.php?rid=5361589&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01865.x Conclusion:  Variations in the interleukin 1 receptor antagonist gene (rs419598) – and not only in the IL1B gene (rs1800587) – are determinants of a predisposition to postorthodontic EARR. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5361589 Tue, 04 Oct 2011 04:00:00 +0100 5361589 http://www.medworm.com/index.php?rid=5286330&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01865.x Conclusion:  Variations in the interleukin 1 receptor antagonist gene (rs419598)—and not only in the IL1B gene (rs1800587)—are determinants of a predisposition to post‐orthodontic EARR. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5286330 Tue, 04 Oct 2011 04:00:00 +0100 5286330 http://www.medworm.com/index.php?rid=5286331&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01863.x AbstractSeveral new technologies are providing useful diagnostic tools and new information related to the pathogenesis of certain oral diseases. In this review, we describe several of these technologies including gene and microRNA arrays, proteomics, and antigen arrays as they relate to the study of Sjögren’s syndrome and head and neck cancer. A common theme is the systematic analysis of large scale inventories of RNAs, proteins, and autoantibody biomarkers revealing information not previously recognized. We also discuss metagenomic approaches that characterize the many different microorganisms present in the oral cavity that may impact oral and human health. Lastly, we describe applications of a new type of antibody profiling technology termed Luciferase Immunoprecipitation Systems (LI... Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5286331 Mon, 03 Oct 2011 04:00:00 +0100 5286331 http://www.medworm.com/index.php?rid=5305029&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01868.x Conclusions: Immunosuppressed animal model DBA/2 is a relevant model for experimental Candida oral colonization and the treatment with probiotics in this model may be an effective alternative to prevent it. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5305029 Sat, 01 Oct 2011 04:00:00 +0100 5305029 http://www.medworm.com/index.php?rid=5286329&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01864.x Conclusion:  The odontologists’ familiarity with the orofacial pathology associated with Cri‐du‐chat syndrome and with the specific needs such disorder conveys should improve the quality of the buccodental treatment these professionals may offer to these patients. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5286329 Sat, 01 Oct 2011 04:00:00 +0100 5286329 http://www.medworm.com/index.php?rid=5274575&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01862.x Conclusion:  The current findings suggest a correlation between dental alterations and mutations in the runt domain of RUNX2 in CCD patients. Further clinical and genetic studies are needed to clarify the relationship between phenotypes and genotypes in CCD and to identify other factors that might influence the clinical features of this uncommon disease. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5274575 Sat, 01 Oct 2011 04:00:00 +0100 5274575 http://www.medworm.com/index.php?rid=5274577&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01860.x Conclusions:  The CD133+CD44+ subpopulation cells possess stem‐like characteristics. They appear to be the potential targets for future biology therapy of human tongue squamous cell carcinoma. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5274577 Thu, 29 Sep 2011 04:00:00 +0100 5274577 http://www.medworm.com/index.php?rid=5274576&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01861.x Conclusions:  Differentially expressed genes in non‐smoking and non‐drinking patients possibly indicate the presence of a different cellular response to carcinogenic events in these patients. Further studies are warranted to validate this gene set and explore possible therapeutic implications to improve prognosis for these patients. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5274576 Thu, 29 Sep 2011 04:00:00 +0100 5274576 http://www.medworm.com/index.php?rid=5226887&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01858.x Conclusions: CD44 and CD166 localized human salivary serous and mucous acinar cells, respectively. These two cell surface markers will be useful in the isolation of specific populations of salivary acinar cells. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5226887 Mon, 19 Sep 2011 00:53:04 +0100 5226887 http://www.medworm.com/index.php?rid=5274578&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01856.x Conclusion:  These results suggest that (1) reduction in tissue E‐cadherin expression in patients with OPC+ is not permanent, and (2) high numbers of CD8+ T cells can be distributed throughout OPC− tissue under normal E‐cadherin expression. Together, these results extend our previous studies and continue to support a role for CD8+ T cells in host defense against OPC. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5274578 Tue, 13 Sep 2011 04:00:00 +0100 5274578 http://www.medworm.com/index.php?rid=5226889&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01856.x Conclusion:  These results suggest that 1) reduction in tissue E‐cadherin expression in OPC+ patients is not permanent, and 2) high numbers of CD8+ T‐cells can be distributed throughout OPC‐ tissue under normal E‐cadherin expression. Together these results extend our previous studies and continue to support a role for CD8+ T‐cells in host defense against OPC. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5226889 Tue, 13 Sep 2011 04:00:00 +0100 5226889 http://www.medworm.com/index.php?rid=5226888&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01857.x (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5226888 Tue, 13 Sep 2011 04:00:00 +0100 5226888 http://www.medworm.com/index.php?rid=5209685&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2009.01553.x Oral Diseases (2011) 17, 729–730The use of eponyms has long been contentious, but many remain in common use, as discussed elsewhere (Editorial: Oral Diseases. 2009: 15; 185). The use of eponyms in diseases of the head and neck is found mainly in specialties dealing with medically compromised individuals (paediatric dentistry, special care dentistry, oral and maxillofacial medicine, oral and maxillofacial pathology, oral and maxillofacial radiology and oral and maxillofacial surgery) and particularly by hospital‐centred practitioners. This series has selected some of the more recognized relevant eponymous conditions and presents them alphabetically. The information is based largely on data available from MEDLINE and a number of internet websites as noted below: the authors would welcome... Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5209685 Mon, 12 Sep 2011 22:45:12 +0100 5209685 http://www.medworm.com/index.php?rid=5209675&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01855.x Conclusion:  Within the limits of this study, it seems that FAM5C expression does not contribute to chronic periodontitis. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5209675 Mon, 12 Sep 2011 22:44:02 +0100 5209675 http://www.medworm.com/index.php?rid=5286332&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01854.x Conclusions:  Considering the limited relationship between the SCL‐90‐R and MMPI in TMD patients with psychological problems, more comprehensive psychological tests are recommended when clinicians suspect patients with TMD of having accompanying psychological problems. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5286332 Thu, 08 Sep 2011 04:00:00 +0100 5286332 http://www.medworm.com/index.php?rid=5209676&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01854.x Conclusions:  Considering the limited relationship between the SCL‐90‐R and MMPI in TMD patients with psychological problems, more comprehensive psychological tests are recommended when clinicians suspect TMD patients of having accompanying psychological problems. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5209676 Thu, 08 Sep 2011 04:00:00 +0100 5209676 http://www.medworm.com/index.php?rid=5132711&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01853.x Conclusions:  SS IgG acutely and reversibly inhibited muscarinic receptor function, thereby inhibiting the Ca2+ mobilization necessary for activation of K+ currents and α‐fodrin reorganization in HSG cells. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5132711 Tue, 16 Aug 2011 22:02:33 +0100 5132711 http://www.medworm.com/index.php?rid=5132712&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01852.x Conclusion:  Sjögren’s syndrome‐like disease in NOD mice occurs in multiple stages; immunological and physiological abnormalities can be detected before focal inflammation appears and salivary output declines. Extrapolating this knowledge to human subjects could help in understanding the pathogenesis and aide the identification of potential therapeutic targets. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5132712 Mon, 15 Aug 2011 23:00:00 +0100 5132712 http://www.medworm.com/index.php?rid=5120280&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01851.x AbstractEvery human body contains a personalized microbiome that is essential to maintaining health but capable of eliciting disease. The oral microbiomeis particularly imperative to health because it cancause both oral and systemic disease. The oral microbiome rests within biofilms throughout the oral cavity, forming an ecosystem that maintains health when in equilibrium. However, certain ecological shifts in the microbiomeallow pathogens to manifest and cause disease.Severe forms of oral disease may result in systemic disease at different body sites. Microbiomicsand metagenomics are two fields of research that have emerged toidentify the presence of specific microbes in the body and understand the nature of the microbiome activity during both health and disease. The analysis of the micro... Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5120280 Fri, 12 Aug 2011 18:17:55 +0100 5120280 http://www.medworm.com/index.php?rid=5209677&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01851.x Oral Diseases (2011) doi: 10.1111/j.1601‐0825.2011.01851.xEvery human body contains a personalized microbiome that is essential to maintaining health but capable of eliciting disease. The oral microbiome is particularly imperative to health because it can cause both oral and systemic disease. The oral microbiome rests within biofilms throughout the oral cavity, forming an ecosystem that maintains health when in equilibrium. However, certain ecological shifts in the microbiome allow pathogens to manifest and cause disease. Severe forms of oral disease may result in systemic disease at different body sites. Microbiomics and metagenomics are two fields of research that have emerged to identify the presence of specific microbes in the body and understand the nature of the microbiome activity... Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5209677 Thu, 11 Aug 2011 04:00:00 +0100 5209677 http://www.medworm.com/index.php?rid=5110296&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01850.x AbstractIn the current era, various pharmacological agents exist for osteoporosis management, and synthetic Parathyroid Hormone (Teriparatide, Forteo) is one of the treatment options. Depending on the timing of administration, Parathyroid Hormone (PTH) has a unique ability to cause both bone apposition and bone resorption. This review focuses on the effects of PTH on the bone, specifically the jaw bones mandible and maxilla. The paper briefly describes the fundamental mechanism of PTH action at the molecular level, as well as in experimental animals and in humans. It differentiates intermittent administration of PTH, especially at doses tolerated by humans that increase bone strength and prevent bone fractures, from continuous use that may lead to bone loss. In particular, it shows how int... Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5110296 Wed, 10 Aug 2011 17:58:39 +0100 5110296 http://www.medworm.com/index.php?rid=5209679&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01849.x Conclusion:  Sequencing small RNAs in the salivary gland is largely unprecedented, but here, we show the feasibility of discovering novel miRNAs and disease biomarkers by sequencing the transcriptome. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5209679 Tue, 09 Aug 2011 04:00:00 +0100 5209679 http://www.medworm.com/index.php?rid=5110297&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01849.x Conclusion:  Sequencing small RNAs in the salivary gland is largely unprecedented, but here we show the feasibility of discovering novel miRNAs and disease biomarkers by sequencing the transcriptome. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5110297 Mon, 08 Aug 2011 23:00:00 +0100 5110297 http://www.medworm.com/index.php?rid=5098447&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01848.x Conclusion:  This study using limited sample size indicated that oral antibiotic therapy may have a limited efficacy on the bacterial population associated with BRONJ lesions. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5098447 Sat, 06 Aug 2011 16:35:30 +0100 5098447 http://www.medworm.com/index.php?rid=5080513&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01847.x Conclusions:  Most children with oral clefts may have similar behavioral health outcomes to unaffected children, except for increased inattention/hyperactivity risks at older ages. However, low satisfaction with facial appearance, increased exposure to surgeries and lower socioeconomic status may significantly increase behavioral problems. Also, the findings emphasize the need to study the representation of behavioral health professionals on cleft teams and access to behavioral healthcare. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5080513 Mon, 01 Aug 2011 15:33:20 +0100 5080513 http://www.medworm.com/index.php?rid=5070472&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01846.x Conclusions:  MDSCs contribute to oral tumor progression and represent a potential target for immunotherapy of oral cancer. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5070472 Thu, 28 Jul 2011 04:00:18 +0100 5070472 http://www.medworm.com/index.php?rid=5162840&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01846.x Conclusions:  Myeloid‐derived suppressor cells contribute to oral tumor progression and represent a potential target for immunotherapy of oral cancer. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5162840 Tue, 26 Jul 2011 23:00:00 +0100 5162840 http://www.medworm.com/index.php?rid=5064152&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01845.x This article reviews current knowledge on molecular findings in premalignant fields in the oral cavity and oropharynx and provides an update on criteria for their identification, discussing the clinical and therapeutic implications. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5064152 Tue, 26 Jul 2011 18:24:33 +0100 5064152 http://www.medworm.com/index.php?rid=5144628&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01845.x This article reviews current knowledge on molecular findings in premalignant fields in the oral cavity and oropharynx and provides an update on criteria for their identification, discussing the clinical and therapeutic implications. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5144628 Sun, 24 Jul 2011 23:00:00 +0100 5144628 http://www.medworm.com/index.php?rid=5064155&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01842.x ABSTRACTLicorice, the name given to the roots and stolons of Glycyrrhiza species, has been used since ancient times as a traditional herbal remedy. Licorice contains several classes of secondary metabolites with which several human health benefits have been associated. Recent research suggests that licorice and its bioactive ingredients such as glycyrrhizin, glabridin, licochalcone A, licoricidin, and licorisoflavan A, possess potential beneficial effects in oral diseases. This paper reviews the effects of licorice and licorice constituents on both the oral microbial pathogens and the host immune response involved in common ora‐dental diseases (dental caries, periodontitis, candidiasis, and recurrent aphthous ulcers). It also summarizes results of clinical trials that investigated the po... Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5064155 Sun, 24 Jul 2011 23:00:00 +0100 5064155 http://www.medworm.com/index.php?rid=5064154&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01843.x Conclusions:  We can suggest that the G allele of MCP‐1 and 64I allele of CCR2 may be risk factors for OSCC. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5064154 Sun, 24 Jul 2011 23:00:00 +0100 5064154 http://www.medworm.com/index.php?rid=5064153&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01844.x Conclusion:  In conclusion, this study has further demonstrated the reliability and responsiveness of the Chronic Oral Mucosal Diseases Questionnaire in assessing quality of life in patients with chronic oral mucosal diseases. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5064153 Sun, 24 Jul 2011 23:00:00 +0100 5064153 http://www.medworm.com/index.php?rid=5053463&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2009.01552.x Oral Diseases (2009) 17, 619–620The use of eponyms has long been contentious, but many remain in common use, as discussed elsewhere (Editorial: Oral Diseases. 2009: 15; 185). The use of eponyms in diseases of the head and neck is found mainly in specialties dealing with medically compromised individuals (paediatric dentistry, special care dentistry, oral and maxillofacial medicine, oral and maxillofacial pathology, oral and maxillofacial radiology and oral and maxillofacial surgery) and particularly by hospital‐centred practitioners. This series has selected some of the more recognized relevant eponymous conditions and presents them alphabetically. The information is based largely on data available from MEDLINE and a number of internet websites as noted below: the authors would welcome... Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5053463 Sat, 23 Jul 2011 16:55:02 +0100 5053463 http://www.medworm.com/index.php?rid=5053462&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01814.x (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5053462 Sat, 23 Jul 2011 16:55:01 +0100 5053462 http://www.medworm.com/index.php?rid=5053461&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01841.x Conclusion:  FASN is expressed in malignant melanocytes, and it can be a helpful marker to distinguish oral melanomas from oral melanocytic nevi. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5053461 Sat, 23 Jul 2011 16:54:40 +0100 5053461 http://www.medworm.com/index.php?rid=5110299&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01841.x Conclusion:  Fatty acid synthase is expressed in malignant melanocytes, and it can be a helpful marker to distinguish oral melanomas from oral melanocytic nevi. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5110299 Thu, 21 Jul 2011 23:00:00 +0100 5110299 http://www.medworm.com/index.php?rid=5110298&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01838.x Conclusions:  Our findings indicate that RUNX3 and WIF1 are frequently aberrantly methylated and that RUNX3 promoter methylation could be considered as a potential prognostic marker in tongue carcinoma. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5110298 Tue, 12 Jul 2011 23:00:00 +0100 5110298 http://www.medworm.com/index.php?rid=5098448&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01839.x Conclusions:  Our data clearly demonstrate that systemic activation of innate immunity accelerates sialoadenitis in a mouse model for SS‐like disease. These findings suggest that chronic activation of innate immunity can influence certain features of SS. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5098448 Tue, 12 Jul 2011 23:00:00 +0100 5098448 http://www.medworm.com/index.php?rid=5031080&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01838.x CONCLUSIONS:  Our findings indicate that RUNX3 and WIF1 are frequently aberrantly methylated, and that RUNX3 promoter methylation could be considered as a potential prognostic marker in tongue carcinoma. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5031080 Tue, 12 Jul 2011 23:00:00 +0100 5031080 http://www.medworm.com/index.php?rid=5031079&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01839.x Conclusions:  Our data clearly demonstrates that systemic activation of innate immunity accelerates sialoadenitis in a mouse model for Sjögren’s syndrome‐like disease. These findings suggest that chronic activation of innate immunity can influence certain features of Sjögren’s syndrome. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5031079 Tue, 12 Jul 2011 23:00:00 +0100 5031079 http://www.medworm.com/index.php?rid=5021495&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01828.x (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5021495 Tue, 12 Jul 2011 23:00:00 +0100 5021495 http://www.medworm.com/index.php?rid=5031078&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01840.x ABSTRACTRecurrent aphthous stomatitis (RAS) is the most common idiopathic intraoral ulcerative disease in the USA. Aphthae typically occur in apparently healthy individuals, although an association with certain systemic diseases has been reported. Despite the unclear etiopathogenesis, new drug trials are continuously conducted in an attempt to reduce pain and dysfunction.We investigated four controversial topics: (1) Is complex aphthosis a mild form of Behçet’s disease (BD)? (2) Is periodic fever, aphthous stomatitis, pharyngitis and adenitis (PFAPA) syndrome a distinct medical entity? (3) Is RAS associated with other systemic diseases (e.g., celiac disease and B12 deficiency)? (4) Are there any new RAS treatments?Results from extensive literature searches, including a systematic review... Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5031078 Thu, 30 Jun 2011 23:00:00 +0100 5031078 http://www.medworm.com/index.php?rid=4999770&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01837.x Conclusion:  Oral infections may trigger malignant transformation in tissues of the mouth and other organs. However, scientific evidence to date remains weak and further well‐conducted studies are warranted before cancer can be properly added to the list of oral infection‐related systemic diseases. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4999770 Thu, 30 Jun 2011 23:00:00 +0100 4999770 http://www.medworm.com/index.php?rid=4978115&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01836.x Conclusion:  These results indicated that both growth factors might function importantly in the wound‐healing process of human gingival tissue via the different regulation of the expression, cell migration, proliferation, and repopulation. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4978115 Wed, 29 Jun 2011 17:31:57 +0100 4978115 http://www.medworm.com/index.php?rid=5040569&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01836.x Conclusion:  These results indicated that both growth factors might function importantly in the wound‐healing process of human gingival tissue via the different regulation of the expression, cell migration, proliferation, and repopulation. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5040569 Mon, 27 Jun 2011 23:00:00 +0100 5040569 http://www.medworm.com/index.php?rid=4970971&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01833.x AbstractDNA methylation is an important regulator of gene transcription, and its role in carcinogenesis has been a topic of considerable interest in the last few years. Of the all epigenetic modifications, methylation, which represses transcription of the promoter region of tumor suppressor genes leading to gene silencing, has been most extensively studied. Oral squamous cell carcinoma (OSCC) has long been known to be the endpoint of many genetic changes, not only genomic mutations but also abnormal epigenetic modifications, as such, promoter methylation, contribute to development of this tumors. Recent studies have shown that promoter methylation of tumor suppressor genes is an important factor in carcinogenesis of OSCC. Some of the main genes that frequently showed promoter methylation i... Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4970971 Mon, 27 Jun 2011 19:04:52 +0100 4970971 http://www.medworm.com/index.php?rid=4970973&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01831.x Conclusions:  In the present study IL4 ‐589 CC, ‐33 CC genotype, and *C allele at both sites appeared to be susceptible while IL6 ‐174 CC genotype and *C allele as protective in patients with OSCC, hence these SNPs may be a potential prognostic markers for tobacco‐related OSCC in Asian Indians (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4970973 Sun, 26 Jun 2011 23:00:00 +0100 4970973 http://www.medworm.com/index.php?rid=4970972&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01832.x Conclusion:  These results suggest that MDOB play a role in cytokine production in response to mechanical stress and that occlusal force may support the maintenance of mandible bone homeostasis by activating bone remodeling through osteoclastogenesis. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4970972 Sun, 26 Jun 2011 23:00:00 +0100 4970972 http://www.medworm.com/index.php?rid=4946827&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01830.x AbstractA reduction in calorie intake (Caloric restriction), appears to consistently decrease the biological rate of aging in a variety of organisms as well as protect against age‐associated diseases including chronic inflammatory disorders such as cardiovascular disease and diabetes. Although the mechanisms behind this observation are not fully understood, identification of the main metabolic pathways affected by caloric restriction has generated interest in finding molecular targets that could be modulated by caloric restriction mimetics. This review describes the general concepts of caloric restriction and caloric restriction mimetics as well as discusses evidence related to their effects on inflammation and chronic inflammatory disorders. Additionally, emerging evidence related to th... Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4946827 Mon, 20 Jun 2011 17:41:38 +0100 4946827 http://www.medworm.com/index.php?rid=4938347&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01829.x Conclusions:  Alendronates seemed to decrease bone resorption but not to decrease bone formation. Empty lacunae were observed significantly more at later time points in implant sites compared to extraction sockets. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4938347 Sat, 18 Jun 2011 17:10:35 +0100 4938347 http://www.medworm.com/index.php?rid=5040570&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01829.x Conclusions:  Alendronates seemed to decrease bone resorption but not to decrease bone formation. Empty lacunae were observed significantly more at later time points in implant sites compared to extraction sockets. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=5040570 Thu, 16 Jun 2011 23:00:00 +0100 5040570 http://www.medworm.com/index.php?rid=4938349&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01826.x Conclusion  This is one of the largest cohorts of OFG patients to have been described in detail. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4938349 Mon, 13 Jun 2011 23:00:00 +0100 4938349 http://www.medworm.com/index.php?rid=4938348&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01827.x (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4938348 Mon, 13 Jun 2011 23:00:00 +0100 4938348 http://www.medworm.com/index.php?rid=4923702&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01825.x CONCLUSIONS:  The predictions of exon 3 skipping in specific DSPP mutations have been validated and a cryptic splicing donor site has been identified. Our data may provide insight into the contribution of DSPP mutations in the pathogenesis and genotype‐phenotype correlations of hereditary dentin defects. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4923702 Mon, 13 Jun 2011 16:53:07 +0100 4923702 http://www.medworm.com/index.php?rid=4923704&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01823.x Conclusion Since all three women had a similar oral phenotype, this new mutation might be involved in the development of the OFD1 oral manifestations. In cases of OFDS, physical examination (including the oral cavity and renal function), and genetic screening of the probands and their relatives are mandatory. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4923704 Fri, 10 Jun 2011 23:00:00 +0100 4923704 http://www.medworm.com/index.php?rid=4923703&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01824.x Conclusions  The results indicate that diabetes affects statherin secretion in labial glands and support the hypothesis that the increased susceptibility to oral diseases associated with diabetes could be related with a reduced statherin secretion. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4923703 Fri, 10 Jun 2011 23:00:00 +0100 4923703 http://www.medworm.com/index.php?rid=4904671&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01822.x Conclusion:  CIH decreases fatigue resistance of genioglossus, and genistein treatment reverses the fatigability of genioglossus by down‐regulation of oxidative stress level and up‐regulation of antioxidant enzymatic activity probably through ERK1/2 signaling pathway. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4904671 Tue, 07 Jun 2011 17:07:31 +0100 4904671 http://www.medworm.com/index.php?rid=4986766&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01821.x Conclusion:  No differences in long‐term whole salivary function after HSCT in adolescents receiving conditioning with sTBI, fTBI or Bu were found. Total systemic exposure to Bu was negatively correlated with stimulated salivary secretion. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4986766 Sun, 05 Jun 2011 23:00:00 +0100 4986766 http://www.medworm.com/index.php?rid=4904672&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01821.x Conclusion:  No differences in long‐term whole salivary function after HSCT in adolescents receiving conditioning with sTBI, fTBI or Bu was found. Total systemic exposure to Bu was negatively correlated with stimulated salivary secretion. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4904672 Sun, 05 Jun 2011 23:00:00 +0100 4904672 http://www.medworm.com/index.php?rid=4886143&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2009.01551.x Oral Diseases (2011) 17, 538–540The use of eponyms has long been contentious, but many remain in common use, as discussed elsewhere (Editorial: Oral Diseases. 2009: 15; 185). The use of eponyms in diseases of the head and neck is found mainly in specialties dealing with medically compromised individuals (paediatric dentistry, special care dentistry, oral and maxillofacial medicine, oral and maxillofacial pathology, oral and maxillofacial radiology and oral and maxillofacial surgery) and particularly by hospital‐centred practitioners. This series has selected some of the more recognized relevant eponymous conditions and presents them alphabetically. The information is based largely on data available from MEDLINE and a number of internet websites as noted below: the authors would welcome... Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4886143 Thu, 02 Jun 2011 15:56:16 +0100 4886143 http://www.medworm.com/index.php?rid=4886141&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01820.x CONCLUSIONS:  Collectively, leptin had a relatively stronger promoting effect on cemento/odontoblastic differentiation and a suppressing effect on adipogenesis in PDLSCs than in DPSCs. This study has provided evidence that leptin acts as an important modulator of dental MSCs differentiation. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4886141 Thu, 02 Jun 2011 15:55:55 +0100 4886141 http://www.medworm.com/index.php?rid=4970977&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01819.x Conclusions:  PKCδ−/− mice have exocrine gland tissue damage indicative of a SS–like phenotype. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4970977 Sun, 22 May 2011 23:00:00 +0100 4970977 http://www.medworm.com/index.php?rid=4843312&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.1812.x (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4843312 Tue, 17 May 2011 23:00:00 +0100 4843312 http://www.medworm.com/index.php?rid=4814547&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01816.x Conclusion:Analysis of these changes provides insight into the protective and predisposing molecular factors that may be involved in the development of Sjögren’s syndrome. Some of the gene changes observed in this study correlate with previously observed sexual dimorphisms in salivary gland function and also illustrate several new targets for further investigation. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4814547 Wed, 11 May 2011 23:00:00 +0100 4814547 http://www.medworm.com/index.php?rid=4854765&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01819.x Conclusions: PKCδ‐/‐ mice have exocrine gland tissue damage indicative of a Sjögren’s Syndrome‐like phenotype. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4854765 Sat, 30 Apr 2011 23:00:00 +0100 4854765 http://www.medworm.com/index.php?rid=4814546&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01817.x Conclusion:Results suggest that salivary CPK can be used as an alternative to serum CPK for diagnosis and monitoring of myocardial infarction. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4814546 Sat, 30 Apr 2011 23:00:00 +0100 4814546 http://www.medworm.com/index.php?rid=4790613&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01815.x Conclusion:  All the nine species analyzed were found to be present in initial carious root lesions as well as sound root surfaces but in different quantities, independent of the different periodontal therapies. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4790613 Sat, 30 Apr 2011 23:00:00 +0100 4790613 http://www.medworm.com/index.php?rid=4759567&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01814.x (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4759567 Thu, 28 Apr 2011 16:03:27 +0100 4759567 http://www.medworm.com/index.php?rid=4748997&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01813.x CONCLUSION:  iNOS can stimulate the expression of VEGF,their expression status may help assess tumor malignancy and patient prognosis. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4748997 Tue, 26 Apr 2011 14:40:46 +0100 4748997 http://www.medworm.com/index.php?rid=4886142&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01813.x Conclusion:  Inducible nitric oxide synthase can stimulate the expression of VEGF, and their expression status may help assess tumor malignancy and patient prognosis. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4886142 Mon, 25 Apr 2011 23:00:00 +0100 4886142 http://www.medworm.com/index.php?rid=4698955&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01812.x (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4698955 Tue, 12 Apr 2011 16:38:07 +0100 4698955 http://www.medworm.com/index.php?rid=4698957&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01810.x Conclusions:  Our data may provide references for cleft lip and cleft palate prevention programs, and counseling programs in China. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4698957 Sun, 10 Apr 2011 23:00:00 +0100 4698957 http://www.medworm.com/index.php?rid=4698956&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01811.x AbstractThe present review focuses on the prominent etiological and pathogenetic aspects of inflammatory bowel disease (IBD), with particular attention being paid to the mucosal immune response to commensal micro‐organisms in health and disease. Pathogenetic implications for target therapy will also be discussed. The clinical presentation, diagnostic aspects, and currently recommended therapeutic options for the 2 main types of IBD are also taken into consideration, including manifestations of these conditions in the oral cavity. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4698956 Sun, 10 Apr 2011 23:00:00 +0100 4698956 http://www.medworm.com/index.php?rid=4687028&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2009.01550.x Oral Diseases (2011) 17, 443–444The use of eponyms has long been contentious, but many remain in common use, as discussed elsewhere (Editorial: Oral Diseases. 2009: 15; 185). The use of eponyms in diseases of the head and neck is found mainly in specialties dealing with medically compromised individuals (paediatric dentistry, special care dentistry, oral and maxillofacial medicine, oral and maxillofacial pathology, oral and maxillofacial radiology and oral and maxillofacial surgery) and particularly by hospital‐centred practitioners. This series has selected some of the more recognized relevant eponymous conditions and presents them alphabetically. The information is based largely on data available from MEDLINE and a number of internet websites as noted below: the authors would welcome... Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4687028 Fri, 08 Apr 2011 16:36:15 +0100 4687028 http://www.medworm.com/index.php?rid=4627934&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01809.x Conclusions:  Reversal of betel quid use and smoking must be considered in accounting for declining trends for oral cancer. Increasing rates of oropharyngeal cancer raises the issue whether risk factors for the oropharynx are different to that of the oral cavity and this may need further investigation. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4627934 Thu, 24 Mar 2011 17:07:13 +0100 4627934 http://www.medworm.com/index.php?rid=4611674&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01808.x AbstractMany of the target molecules that reside in blood are also present in oral fluids, albeit at lower concentrations. Oral fluids are, however, relatively easy and safe to collect without a need for specialized equipment and training. Thus, oral fluids provide convenient samples for medical diagnostics. Recent advances in Lab on a Chip technologies have made minute, fully integrated diagnostic systems practical for an assortment of point of care tests. Such systems can perform either immunoassays or molecular diagnostics outside centralized laboratories within time periods ranging from minutes to an hour. The article briefly reviews recent advances in devices for point of care testing with a focus on work that has been carried out by the authors as part of a NIH program. (Source: Oral... Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4611674 Sat, 19 Mar 2011 16:55:34 +0100 4611674 http://www.medworm.com/index.php?rid=4755203&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01808.x Oral Diseases (2011)Many of the target molecules that reside in blood are also present in oral fluids, albeit at lower concentrations. Oral fluids are, however, relatively easy and safe to collect without the need for specialized equipment and training. Thus, oral fluids provide convenient samples for medical diagnostics. Recent advances in lab‐on‐a‐chip technologies have made minute, fully integrated diagnostic systems practical for an assortment of point‐of‐care tests. Such systems can perform either immunoassays or molecular diagnostics outside centralized laboratories within time periods ranging from minutes to an hour. The article briefly reviews recent advances in devices for point‐of‐care testing with a focus on work that has been carried out by the authors as part of ... Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4755203 Sat, 19 Mar 2011 00:00:00 +0100 4755203 http://www.medworm.com/index.php?rid=4601919&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01807.x Conclusions:  HA possesses fungistatic activity but no candidacidal activity. HA showed inhibitory effects on the candidacidal activities of lysozyme and the peroxidase system. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4601919 Thu, 17 Mar 2011 17:03:38 +0100 4601919 http://www.medworm.com/index.php?rid=4581915&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2009.01549.x Oral Diseases (2011) 17, 342–344The use of eponyms has long been contentious, but many remain in common use, as discussed elsewhere (Editorial: Oral Diseases. 2009: 15; 185). The use of eponyms in diseases of the head and neck is found mainly in specialties dealing with medically compromised individuals (paediatric dentistry, special care dentistry, oral and maxillofacial medicine, oral and maxillofacial pathology, oral and maxillofacial radiology and oral and maxillofacial surgery) and particularly by hospital‐centred practitioners. This series has selected some of the more recognized relevant eponymous conditions and presents them alphabetically. The information is based largely on data available from MEDLINE and a number of internet websites as noted below: the authors would welcome... Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4581915 Mon, 14 Mar 2011 18:30:55 +0100 4581915 http://www.medworm.com/index.php?rid=4562080&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01795.x Conclusions:  (i) Oral medicine clinicians diagnose and manage a wide variety of orofacial conditions; (ii) There are significant differences in the definition of oral medicine clinical practice from country to country; (iii) India has the largest expansion of oral medicine services as defined by escalating numbers of clinicians within the specialty as compared with other countries; (iv) oral medicine practitioners have a wide range of professional responsibilities. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4562080 Wed, 09 Mar 2011 17:02:57 +0100 4562080 http://www.medworm.com/index.php?rid=4562079&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01785.x Conclusions:  This preliminary study provides the first evidence regarding international Oral Medicine postgraduate training, from which recommendations for an international core curriculum could be initiated. It is through such an initiative that a universal clinical core syllabus in postgraduate Oral Medicine training may be more feasible. (Source: Oral Diseases) Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4562079 Wed, 09 Mar 2011 17:02:56 +0100 4562079 http://www.medworm.com/index.php?rid=4562078&cid=s_25321_16_f&fid=25321&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1601-0825.2011.01794.x Oral Diseases (2011) 17 (Suppl. 1), 85–94The implementation of information technology in healthcare is a significant focus for many nations around the world. However, information technology support for clinical care, research and education in oral medicine is currently poorly developed. This situation hampers our ability to transform oral medicine into a ‘learning healthcare discipline’ in which the divide between clinical practice and research is diminished and, ultimately, eliminated. This paper reviews the needs of and requirements for information technology support of oral medicine and proposes an agenda designed to meet those needs. For oral medicine, this agenda includes analyzing and reviewing current clinical and documentation practices, working toward progressively standardi... Oral Diseases journals http://www.medworm.com/rss/comments.php?id=4562078 Wed, 09 Mar 2011 17:02:56 +0100 4562078