Organic Process Research via MedWorm.com MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Organic Process Research' source. Sat, 15 Jan 2011 23:08:02 +0100 Development of a Practical Synthesis of a Pyrazolopyridinone-Based p38 MAP Kinase Inhibitor http://www.medworm.com/index.php?rid=4174804&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FcZsKtGMSmvs%2Fop100205s Organic Process Research & DevelopmentDOI: 10.1021/op100205s (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4174804 Tue, 16 Nov 2010 14:29:02 +0100 4174804 Development of a Second-Generation, Highly Efficient Manufacturing Route for the HIV Integrase Inhibitor Raltegravir Potassium http://www.medworm.com/index.php?rid=4171189&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FGPrSOMFwW4k%2Fop100257r Organic Process Research & DevelopmentDOI: 10.1021/op100257r (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4171189 Tue, 16 Nov 2010 05:18:47 +0100 4171189 Diastereoisomeric Salt Formation and Enzyme-Catalyzed Kinetic Resolution as Complementary Methods for the Chiral Separation of cis-/trans-Enantiomers of 3-Aminocyclohexanol http://www.medworm.com/index.php?rid=4171190&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FwxTiWyJ0j-8%2Fop1002424 Organic Process Research & DevelopmentDOI: 10.1021/op1002424 (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4171190 Mon, 15 Nov 2010 18:09:27 +0100 4171190 Dialkyl Sulfide Stabilisation in a Catalytic Dicuprate 1,6-Dienone Addition Process http://www.medworm.com/index.php?rid=4154549&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FGAynDCMPRcU%2Fop1002648 Organic Process Research & DevelopmentDOI: 10.1021/op1002648 (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4154549 Wed, 10 Nov 2010 18:17:36 +0100 4154549 An Efficient and Scalable Synthesis of the Spirocyclic Glycine Transporter Inhibitor GSK2137305 http://www.medworm.com/index.php?rid=4154550&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2Fwrj0RVWWU44%2Fop100210s Organic Process Research & DevelopmentDOI: 10.1021/op100210s (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4154550 Wed, 10 Nov 2010 18:16:57 +0100 4154550 Some Items of Interest to Process R&D Chemists and Engineers http://www.medworm.com/index.php?rid=4138279&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FGVEurGgsEtM%2Fop1002819 Organic Process Research & DevelopmentDOI: 10.1021/op1002819 (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4138279 Thu, 04 Nov 2010 17:39:19 +0100 4138279 In Situ Determination of Metastable Zone Width Using Dielectric Constant Measurement http://www.medworm.com/index.php?rid=4131893&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FHzoir3AVmZI%2Fop100182s Organic Process Research & DevelopmentDOI: 10.1021/op100182s (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4131893 Wed, 03 Nov 2010 04:52:11 +0100 4131893 Development of a New Practical Synthesis of a 5-HT2C Receptor Agonist http://www.medworm.com/index.php?rid=4131894&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FmtguNwljs5s%2Fop100233f Organic Process Research & DevelopmentDOI: 10.1021/op100233f (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4131894 Tue, 02 Nov 2010 17:40:24 +0100 4131894 An Integrated Chemo-enzymatic Route for Preparation of β-Thymidine, a Key Intermediate in the Preparation of Antiretrovirals http://www.medworm.com/index.php?rid=4131895&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FfIC7fr17ycw%2Fop100208x Organic Process Research & DevelopmentDOI: 10.1021/op100208x (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4131895 Tue, 02 Nov 2010 17:39:54 +0100 4131895 Sustainability and Biotechnology http://www.medworm.com/index.php?rid=4116329&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2Fhlw0sl8BQSE%2Fop100206p Organic Process Research & DevelopmentDOI: 10.1021/op100206p (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4116329 Thu, 28 Oct 2010 14:31:13 +0100 4116329 The Continuous Acid-Catalysed Etherification of Aliphatic Alcohols Using Stoichiometric Quantities of Dialkyl Carbonates http://www.medworm.com/index.php?rid=4116330&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FVWv_899iNRE%2Fop1002243 Organic Process Research & DevelopmentDOI: 10.1021/op1002243 (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4116330 Wed, 27 Oct 2010 14:49:42 +0100 4116330 Development of a Practical and Efficient Synthesis of Chloromethyl 2-Ethoxy-2-methylpropanoate http://www.medworm.com/index.php?rid=4116331&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FZu5lO6GI4kE%2Fop1002038 Organic Process Research & DevelopmentDOI: 10.1021/op1002038 (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4116331 Wed, 27 Oct 2010 14:49:25 +0100 4116331 Solvent-Free and Safe Process for the Quantitative Production of Phosgene from Triphosgene by Deactivated Imino-Based Catalysts http://www.medworm.com/index.php?rid=4116332&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FtoU8pO_CKek%2Fop100239n Organic Process Research & DevelopmentDOI: 10.1021/op100239n (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4116332 Tue, 26 Oct 2010 15:44:53 +0100 4116332 Organic Solvent Nanofiltration: A New Paradigm in Peptide Synthesis http://www.medworm.com/index.php?rid=4116333&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FGS7TboEHwIo%2Fop1001403 Organic Process Research & DevelopmentDOI: 10.1021/op1001403 (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4116333 Tue, 26 Oct 2010 10:52:31 +0100 4116333 Safety Evaluation of Sodium Borohydride in Dimethylacetamide http://www.medworm.com/index.php?rid=4116334&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2F9kdorm5F-DM%2Fop1002566 Organic Process Research & DevelopmentDOI: 10.1021/op1002566 (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4116334 Tue, 26 Oct 2010 10:51:42 +0100 4116334 The Impact of Operating Parameters on the Polymorphic Transformation of d-Mannitol Characterized in Situ with Raman Spectroscopy, FBRM, and PVM http://www.medworm.com/index.php?rid=4095304&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FkMuDQ120HrM%2Fop100228f Organic Process Research & DevelopmentDOI: 10.1021/op100228f (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4095304 Thu, 21 Oct 2010 20:16:49 +0100 4095304 Modified Chelation-Controlled Reduction of an N-Acryloyloxazolidin-2-one http://www.medworm.com/index.php?rid=4095306&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FdAii3wkor3g%2Fop100074m Organic Process Research & DevelopmentDOI: 10.1021/op100074m (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4095306 Thu, 21 Oct 2010 14:34:36 +0100 4095306 2-Bromo-3-(cyclohexyloxy)acrylaldehyde: An Isolable Enol Ether of Bromomalonaldehyde Suitable for Use in the Manufacture of Imidazolecarboxaldehydes http://www.medworm.com/index.php?rid=4095305&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FIdau0RRwJtk%2Fop100156y Organic Process Research & DevelopmentDOI: 10.1021/op100156y (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4095305 Thu, 21 Oct 2010 04:34:37 +0100 4095305 Guidelines and Cost Analysis for Catalyst Production in Biocatalytic Processes http://www.medworm.com/index.php?rid=4095307&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FI7XZeenCrrw%2Fop1002165 Organic Process Research & DevelopmentDOI: 10.1021/op1002165 (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4095307 Wed, 20 Oct 2010 17:56:11 +0100 4095307 Safety Special Section Editorial http://www.medworm.com/index.php?rid=4085275&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2Ft-IaDI835lo%2Fop100274x Organic Process Research & DevelopmentDOI: 10.1021/op100274x (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4085275 Wed, 20 Oct 2010 04:29:58 +0100 4085275 A Kilolaboratory Preparation of the CNRS Chiral Auxiliary http://www.medworm.com/index.php?rid=4085274&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FfSorqZ192zE%2Fop1002227 Organic Process Research & DevelopmentDOI: 10.1021/op1002227 (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4085274 Wed, 20 Oct 2010 04:29:58 +0100 4085274 Referees/Reviewers: Where Are You Now? http://www.medworm.com/index.php?rid=4085276&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FBWFfHjcpgjo%2Fop100275c Organic Process Research & DevelopmentDOI: 10.1021/op100275c (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4085276 Tue, 19 Oct 2010 19:40:42 +0100 4085276 Application of Quality by Design Principles for the Definition of a Robust Crystallization Process for Casopitant Mesylate http://www.medworm.com/index.php?rid=4081093&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FEGu5-JpnCZ4%2Fop100209c Organic Process Research & DevelopmentDOI: 10.1021/op100209c (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4081093 Mon, 18 Oct 2010 04:04:55 +0100 4081093 A Review of U.S. Patents in the Field of Organic Process Development Published During June and July 2010 http://www.medworm.com/index.php?rid=4072553&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FwLu-f_cHgko%2Fop100263j Organic Process Research & DevelopmentDOI: 10.1021/op100263j (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4072553 Fri, 15 Oct 2010 18:57:06 +0100 4072553 Dexmethylphenidate: An Efficient Process for the Racemization of Unwanted (2S,2′S or l-threo)-α-Phenyl-α-(2-piperidyl)acetamide http://www.medworm.com/index.php?rid=4072554&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FVlO6BkmCNfo%2Fop100197g Organic Process Research & DevelopmentDOI: 10.1021/op100197g (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4072554 Fri, 15 Oct 2010 04:58:28 +0100 4072554 Practical Access to Metallo Thiophenes: Regioselective Synthesis of 2,4-Disubstituted Thiophenes http://www.medworm.com/index.php?rid=4064265&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FtNsUbWOuNow%2Fop100226k Organic Process Research & DevelopmentDOI: 10.1021/op100226k (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4064265 Wed, 13 Oct 2010 14:59:13 +0100 4064265 Monitoring Temperature Effect on the Polymorphic Transformation of Acitretin Using FBRM−Lasentec http://www.medworm.com/index.php?rid=4035339&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FEhI806fd6BI%2Fop100177s Organic Process Research & DevelopmentDOI: 10.1021/op100177s (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4035339 Tue, 05 Oct 2010 15:19:04 +0100 4035339 Green Progression for Synthesis of Regioselective β-Amino Alcohols and Chemoselective Alkylated Indoles http://www.medworm.com/index.php?rid=4035340&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2F1sjNevrGemE%2Fop1002177 Organic Process Research & DevelopmentDOI: 10.1021/op1002177 (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4035340 Tue, 05 Oct 2010 14:01:13 +0100 4035340 A Switchable Oxidation Process Leading to Two Various Versatile Pharmaceutical Intermediates http://www.medworm.com/index.php?rid=4035341&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FFvvU9d8-Evo%2Fop100185x Organic Process Research & DevelopmentDOI: 10.1021/op100185x (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4035341 Tue, 05 Oct 2010 13:43:50 +0100 4035341 Scaleable Preparation of Sensitive Functionalized Aromatics and Heteroaromatics via Directed Metalation Using tmpZnCl·LiCl http://www.medworm.com/index.php?rid=4030118&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FZik0PUtydWs%2Fop1001935 Organic Process Research & DevelopmentDOI: 10.1021/op1001935 (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4030118 Mon, 04 Oct 2010 17:16:19 +0100 4030118 Optimization of a Hydrogenation Process using Real-Time Mid-IR, Heat Flow and Gas Uptake Measurements http://www.medworm.com/index.php?rid=4030119&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FhgZsPXdbRV4%2Fop100169j Organic Process Research & DevelopmentDOI: 10.1021/op100169j (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4030119 Mon, 04 Oct 2010 15:07:54 +0100 4030119 Novel Preparation of H1 Receptor Antagonist Fexofenadine http://www.medworm.com/index.php?rid=4030120&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FF1BsFC_2h7Q%2Fop100090j Organic Process Research & DevelopmentDOI: 10.1021/op100090j (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4030120 Mon, 04 Oct 2010 15:06:27 +0100 4030120 A Mechanistic Insight into a Simple C−N Bond Formation via SN2 Displacement: A Synergistic Kinetics and Design of Experiment Approach http://www.medworm.com/index.php?rid=4030121&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FYyLrE4Yezqw%2Fop100176u Organic Process Research & DevelopmentDOI: 10.1021/op100176u (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4030121 Mon, 04 Oct 2010 13:35:45 +0100 4030121 Book Review of Asymmetric Catalysis on Industrial Scale: Challenges, Approaches and Solutions http://www.medworm.com/index.php?rid=4025157&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FGiV6sXXYZdQ%2Fop100232t Organic Process Research & DevelopmentDOI: 10.1021/op100232t (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4025157 Fri, 01 Oct 2010 19:00:14 +0100 4025157 A Kinetic and Mass Transfer Model for Glycerol Hydrogenolysis in a Trickle-Bed Reactor http://www.medworm.com/index.php?rid=4021840&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FYzI2Lnan6wc%2Fop900336a Organic Process Research & DevelopmentDOI: 10.1021/op900336a (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4021840 Fri, 01 Oct 2010 04:30:04 +0100 4021840 A Novel Dewar-Like Reactor for Maintaining Constant Heat and Enhancing Product Yields during Microwave-Assisted Organic Syntheses http://www.medworm.com/index.php?rid=4010887&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FUIXM7SXqTHc%2Fop100181u Organic Process Research & DevelopmentDOI: 10.1021/op100181u (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4010887 Wed, 29 Sep 2010 13:28:44 +0100 4010887 Initial Scale-Up and Process Improvements for the Preparation of a Lead Antibacterial Macrolone Compound http://www.medworm.com/index.php?rid=4010888&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2Fyq4Tyc17Bf8%2Fop100199t Organic Process Research & DevelopmentDOI: 10.1021/op100199t (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4010888 Tue, 28 Sep 2010 18:40:11 +0100 4010888 The Synthesis of Two Potent β-3 Adrenergic Receptor Agonists http://www.medworm.com/index.php?rid=4010889&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FkGRN_VFV_qw%2Fop1001462 Organic Process Research & DevelopmentDOI: 10.1021/op1001462 (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=4010889 Tue, 28 Sep 2010 13:59:04 +0100 4010889 Convenient Method for Synthesis of N-Protected α-Amino Epoxides: Key Intermediates for HIV Protease Inhibitors http://www.medworm.com/index.php?rid=3997595&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2Fg1VQ2SksydI%2Fop100174j Organic Process Research & DevelopmentDOI: 10.1021/op100174j (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3997595 Thu, 23 Sep 2010 17:03:42 +0100 3997595 Resolution of (±)-Imeglimin-2,4-dichlorophenylacetate Methanol Solvate by Preferential Crystallization http://www.medworm.com/index.php?rid=3979902&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FQRqwBxESV-Q%2Fop100173r Organic Process Research & DevelopmentDOI: 10.1021/op100173r (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3979902 Fri, 17 Sep 2010 15:33:47 +0100 3979902 Selective Hydrogenolysis of Glycerol to 1,2-Propanediol: Comparison of Batch and Continuous Process Operations http://www.medworm.com/index.php?rid=3968356&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FRDjmiCc-3fY%2Fop1001897 Organic Process Research & DevelopmentDOI: 10.1021/op1001897 (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3968356 Tue, 14 Sep 2010 20:16:42 +0100 3968356 Development of Drug Substances as Mixture of Polymorphs: Studies to Control Form 3 in Casopitant Mesylate http://www.medworm.com/index.php?rid=3968357&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2Fev07OpcMtQc%2Fop100150b Organic Process Research & DevelopmentDOI: 10.1021/op100150b (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3968357 Tue, 14 Sep 2010 19:44:09 +0100 3968357 Overcoming the Challenges of Solid Bridging and Constriction during Pd-Catalyzed C−N Bond Formation in Microreactors http://www.medworm.com/index.php?rid=3957135&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2F2YBpehvPNKU%2Fop100154d Organic Process Research & DevelopmentDOI: 10.1021/op100154d (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3957135 Fri, 10 Sep 2010 04:22:05 +0100 3957135 Process Development for a Large Scale Stereoselective Synthesis of (Z)-(1-Bromobut-1-ene-1,2-diyl)dibenzene, a Key Intermediate of a Selective Estrogen Receptor Modulator http://www.medworm.com/index.php?rid=3951436&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FvzBN5WP8MqE%2Fop100112r Organic Process Research & DevelopmentDOI: 10.1021/op100112r (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3951436 Thu, 02 Sep 2010 12:44:30 +0100 3951436 Some Items of Interest to Process R&D Chemists and Engineers http://www.medworm.com/index.php?rid=3951437&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FFpha6cHK-hE%2Fop100229b Organic Process Research & DevelopmentDOI: 10.1021/op100229b (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3951437 Wed, 01 Sep 2010 15:05:11 +0100 3951437 Efficient Synthesis of 1,3-Dialkylimidazolium-Based Ionic Liquids: The Modified Continuous Radziszewski Reaction in a Microreactor Setup http://www.medworm.com/index.php?rid=3919585&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100055f%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3919585 Tue, 31 Aug 2010 10:33:52 +0100 3919585 Process Development and Pilot-Plant Synthesis of (2-Chlorophenyl)[2-(phenylsulfonyl)pyridin-3-yl]methanone http://www.medworm.com/index.php?rid=3951438&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2F7ly_2HOh_Yg%2Fop100157q Organic Process Research & DevelopmentDOI: 10.1021/op100157q (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3951438 Tue, 31 Aug 2010 04:19:01 +0100 3951438 Efficient Synthesis of 1,3-Dialkylimidazolium-Based Ionic Liquids: The Modified Continuous Radziszewski Reaction in a Microreactor Setup http://www.medworm.com/index.php?rid=3951439&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FkMU5N2uvGeQ%2Fop100055f Organic Process Research & DevelopmentDOI: 10.1021/op100055f (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3951439 Mon, 30 Aug 2010 17:26:47 +0100 3951439 An Efficient Scalable Route for the Synthesis of Enantiomerically Pure tert-Butyl-(1R,4S,6R)-4-(hydroxymethyl)-3-azabicyclo[4.1.0]heptane-3-carboxylate http://www.medworm.com/index.php?rid=3906729&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100164v%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3906729 Thu, 26 Aug 2010 10:07:11 +0100 3906729 A Facile Microwave-Mediated Drying Process of Thermally Unstable / Labile Products http://www.medworm.com/index.php?rid=3902214&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100102m%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3902214 Wed, 25 Aug 2010 10:06:57 +0100 3902214 Process Improvements for the Manufacture of Tenofovir Disoproxil Fumarate at Commercial Scale http://www.medworm.com/index.php?rid=3951441&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FFIj5JG_-jKw%2Fop1001337 Organic Process Research & DevelopmentDOI: 10.1021/op1001337 (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3951441 Tue, 24 Aug 2010 17:24:04 +0100 3951441 A Facile Microwave-Mediated Drying Process of Thermally Unstable / Labile Products http://www.medworm.com/index.php?rid=3951442&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FsyErrXwSU_U%2Fop100102m Organic Process Research & DevelopmentDOI: 10.1021/op100102m (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3951442 Tue, 24 Aug 2010 17:22:53 +0100 3951442 Erratum: Highly Diastereoselective Hydrogenation of Imines by a Bimetallic Pd−Cu Heterogeneous Catalyst http://www.medworm.com/index.php?rid=3898606&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100212e%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3898606 Tue, 24 Aug 2010 10:05:16 +0100 3898606 Highly Diastereoselective Hydrogenation of Imines by a Bimetallic Pd−Cu Heterogeneous Catalyst http://www.medworm.com/index.php?rid=3951443&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2Fy-lQRM0EPV0%2Fop100212e Organic Process Research & DevelopmentDOI: 10.1021/op100212e (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3951443 Tue, 24 Aug 2010 08:03:04 +0100 3951443 Hydrolysis of Phosphoryl Trichloride (POCl3): Characterization, in Situ Detection, and Safe Quenching of Energetic Metastable Intermediates http://www.medworm.com/index.php?rid=3898607&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop1001484%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3898607 Mon, 23 Aug 2010 16:51:06 +0100 3898607 Process Research and Development for the Kilogram Manufacture of the SRC Kinase Inhibitor AZD0530 http://www.medworm.com/index.php?rid=3951445&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FA5mnDC4JZO0%2Fop100161y Organic Process Research & DevelopmentDOI: 10.1021/op100161y (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3951445 Mon, 23 Aug 2010 13:46:45 +0100 3951445 Development of an Efficient and Practical Route for the Multikilogram Manufacture of the SRC Kinase Inhibitor AZD0530 http://www.medworm.com/index.php?rid=3951446&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FLS7CXlVbB00%2Fop100163m Organic Process Research & DevelopmentDOI: 10.1021/op100163m (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3951446 Mon, 23 Aug 2010 13:46:44 +0100 3951446 Hydrolysis of Phosphoryl Trichloride (POCl3): Characterization, in Situ Detection, and Safe Quenching of Energetic Metastable Intermediates http://www.medworm.com/index.php?rid=3951444&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FqMj4-TnrD2o%2Fop1001484 Organic Process Research & DevelopmentDOI: 10.1021/op1001484 (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3951444 Mon, 23 Aug 2010 04:51:06 +0100 3951444 Amide Bond Formation via Reversible, Carboxylic Acid-Promoted Lactone Aminolysis http://www.medworm.com/index.php?rid=3890256&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop1001269%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3890256 Sat, 21 Aug 2010 10:09:31 +0100 3890256 Goodbye to an Old Friend http://www.medworm.com/index.php?rid=3951447&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2Ff2vCOjRZL4Q%2Fop1002006 Organic Process Research & DevelopmentDOI: 10.1021/op1002006 (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3951447 Fri, 20 Aug 2010 17:25:34 +0100 3951447 Regulatory Highlights for March−August 2010 http://www.medworm.com/index.php?rid=3951449&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FyqHoT-cBVB8%2Fop1002215 Organic Process Research & DevelopmentDOI: 10.1021/op1002215 (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3951449 Fri, 20 Aug 2010 14:12:40 +0100 3951449 An Automated Microfluidic System for Online Optimization in Chemical Synthesis http://www.medworm.com/index.php?rid=3888293&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100123e%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3888293 Fri, 20 Aug 2010 10:06:00 +0100 3888293 Amide Bond Formation via Reversible, Carboxylic Acid-Promoted Lactone Aminolysis http://www.medworm.com/index.php?rid=3951448&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FBh_og5yl-wE%2Fop1001269 Organic Process Research & DevelopmentDOI: 10.1021/op1001269 (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3951448 Fri, 20 Aug 2010 04:53:49 +0100 3951448 An Automated Microfluidic System for Online Optimization in Chemical Synthesis http://www.medworm.com/index.php?rid=3951450&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FJRwXhunFueg%2Fop100123e Organic Process Research & DevelopmentDOI: 10.1021/op100123e (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3951450 Thu, 19 Aug 2010 14:31:37 +0100 3951450 Biotransformation of (+)-Catechin to Novel B-Ring Fission Lactones http://www.medworm.com/index.php?rid=3879979&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100108j%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3879979 Wed, 18 Aug 2010 10:09:53 +0100 3879979 Robust Synthesis of Methyl 5-Chloro-4-fluoro-1H-indole-2-carboxylate: A Key Intermediate in the Preparation of an HIV NNRTI Candidate http://www.medworm.com/index.php?rid=3875689&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop1001808%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3875689 Tue, 17 Aug 2010 10:06:27 +0100 3875689 Book Report of Cinchona Alkaloids in Synthesis and Catalysis: Ligands, Immobilization and Organocatalysis http://www.medworm.com/index.php?rid=3951452&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FHvLvgbsHbeM%2Fop100213x Organic Process Research & DevelopmentDOI: 10.1021/op100213x (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3951452 Mon, 16 Aug 2010 14:19:58 +0100 3951452 Robust Synthesis of Methyl 5-Chloro-4-fluoro-1H-indole-2-carboxylate: A Key Intermediate in the Preparation of an HIV NNRTI Candidate http://www.medworm.com/index.php?rid=3951453&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FLRwqcpSr5KU%2Fop1001808 Organic Process Research & DevelopmentDOI: 10.1021/op1001808 (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3951453 Mon, 16 Aug 2010 14:19:18 +0100 3951453 A Calibration-Free Application of Raman Spectroscopy to the Monitoring of Mannitol Crystallization and Its Polymorphic Transformation http://www.medworm.com/index.php?rid=3861201&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100142k%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3861201 Thu, 12 Aug 2010 10:05:40 +0100 3861201 Discovery and Development of an Efficient, Scalable, and Robust Route to the Novel CENP-E Inhibitor GSK923295A http://www.medworm.com/index.php?rid=3857486&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100186c%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3857486 Wed, 11 Aug 2010 10:07:16 +0100 3857486 Enzymatic Preparation of an (S)-Amino Acid from a Racemic Amino Acid http://www.medworm.com/index.php?rid=3853595&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop1001534%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3853595 Tue, 10 Aug 2010 10:07:16 +0100 3853595 Davis Oxaziridine-Mediated Asymmetric Synthesis of Proton Pump Inhibitors Using DBU Salt of Prochiral Sulfide http://www.medworm.com/index.php?rid=3830705&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100075v%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3830705 Fri, 06 Aug 2010 10:22:09 +0100 3830705 Development of an Efficient Synthesis of Two CRF Antagonists for the Treatment of Neurological Disorders http://www.medworm.com/index.php?rid=3805097&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop1001512%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3805097 Fri, 30 Jul 2010 10:11:55 +0100 3805097 A Review of U.S. Patents in the Field of Organic Process Development Published During April and May 2010 http://www.medworm.com/index.php?rid=3797859&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100191c%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3797859 Wed, 28 Jul 2010 10:08:33 +0100 3797859 Scaleup of Lipase-Catalyzed Polyester Synthesis http://www.medworm.com/index.php?rid=3793922&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop1000868%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3793922 Tue, 27 Jul 2010 10:36:45 +0100 3793922 Optimization of the Epoxidation of Rapeseed Oil with Peracetic Acid http://www.medworm.com/index.php?rid=3951460&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FwOWgO1fBu5o%2Fop900240p Organic Process Research & DevelopmentDOI: 10.1021/op900240p (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3951460 Mon, 26 Jul 2010 20:11:02 +0100 3951460 Scaleup of Lipase-Catalyzed Polyester Synthesis http://www.medworm.com/index.php?rid=3951461&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FROtDaFCmWyA%2Fop1000868 Organic Process Research & DevelopmentDOI: 10.1021/op1000868 (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3951461 Mon, 26 Jul 2010 19:12:24 +0100 3951461 Process for the Preparation of an Amorphous, Peptide-like Diabetes Drug: Approach to a Chromatography-Free Process http://www.medworm.com/index.php?rid=3785993&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100084r%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3785993 Sat, 24 Jul 2010 10:28:48 +0100 3785993 Development of a Catalytic Cuprate 1,6-Conjugate Dienone Addition Process for the Manufacture of Fulvestrant EAS, a Key Intermediate in the Synthesis of Fulvestrant http://www.medworm.com/index.php?rid=3951462&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FAuZXQWWA97I%2Fop1001319 Organic Process Research & DevelopmentDOI: 10.1021/op1001319 (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3951462 Fri, 23 Jul 2010 19:56:39 +0100 3951462 Process for the Preparation of an Amorphous, Peptide-like Diabetes Drug: Approach to a Chromatography-Free Process http://www.medworm.com/index.php?rid=3951463&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FTmgDkylxcyI%2Fop100084r Organic Process Research & DevelopmentDOI: 10.1021/op100084r (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3951463 Fri, 23 Jul 2010 15:09:10 +0100 3951463 Practical Synthesis of (1s,4s)-4-(Methylamino)-1′H-spiro[cyclohexane-1,3′-furo[3,4-c]pyridin]-1′-one http://www.medworm.com/index.php?rid=3779725&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100138t%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3779725 Thu, 22 Jul 2010 10:07:26 +0100 3779725 Pilot-Plant Study of the PCB Degradation at Ambient Temperature and Pressure http://www.medworm.com/index.php?rid=3775659&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100107r%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3775659 Wed, 21 Jul 2010 10:07:49 +0100 3775659 An Optimized Process to 10-Bromo-1-decanol http://www.medworm.com/index.php?rid=3775661&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100143t%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3775661 Tue, 20 Jul 2010 16:37:27 +0100 3775661 Protein-Mediated Nitroaldol Addition in Aqueous Media. Catalytic Promiscuity or Unspecific Catalysis? http://www.medworm.com/index.php?rid=3775660&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100130c%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3775660 Tue, 20 Jul 2010 16:35:16 +0100 3775660 The Continuous Catalytic Debenzylation of 1,4-Dibenzyloxybenzene with H2 in THF Expanded with High Pressure CO2 http://www.medworm.com/index.php?rid=3771353&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100136g%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3771353 Tue, 20 Jul 2010 10:10:16 +0100 3771353 An Optimized Process to 10-Bromo-1-decanol http://www.medworm.com/index.php?rid=3951466&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2Fx1be55FEGQo%2Fop100143t Organic Process Research & DevelopmentDOI: 10.1021/op100143t (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3951466 Tue, 20 Jul 2010 04:37:27 +0100 3951466 Protein-Mediated Nitroaldol Addition in Aqueous Media. Catalytic Promiscuity or Unspecific Catalysis? http://www.medworm.com/index.php?rid=3951467&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FvuraFVYfsBE%2Fop100130c Organic Process Research & DevelopmentDOI: 10.1021/op100130c (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3951467 Tue, 20 Jul 2010 04:35:16 +0100 3951467 The Continuous Catalytic Debenzylation of 1,4-Dibenzyloxybenzene with H2 in THF Expanded with High Pressure CO2 http://www.medworm.com/index.php?rid=3951468&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2F6vGjbYmSgss%2Fop100136g Organic Process Research & DevelopmentDOI: 10.1021/op100136g (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3951468 Mon, 19 Jul 2010 20:45:49 +0100 3951468 Is there a Future for Organic Chemists in the Pharmaceutical Industry outside China and India? http://www.medworm.com/index.php?rid=3762689&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop1001676%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 14, Issue 4, Page 749, July 2010. (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3762689 Fri, 16 Jul 2010 04:00:00 +0100 3762689 Book Review of Heterocyclic Chemistry http://www.medworm.com/index.php?rid=3739937&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100184e%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3739937 Fri, 09 Jul 2010 10:09:01 +0100 3739937 A Practical Synthesis of the PDE4 Inhibitor, KW-4490 http://www.medworm.com/index.php?rid=3739938&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop1001287%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3739938 Thu, 08 Jul 2010 16:35:48 +0100 3739938 Development of a Dynamic Kinetic Resolution for the Isolation of an Intermediate in the Synthesis of Casopitant Mesylate: Application of QbD Principles in the Definition of the Parameter Ranges, Issues in the Scale-Up and Mitigation Strategies http://www.medworm.com/index.php?rid=3739939&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100121s%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3739939 Thu, 08 Jul 2010 16:35:09 +0100 3739939 Book Review of Practical Methods for Biocatalysis and Biotransformations http://www.medworm.com/index.php?rid=3736416&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100183p%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3736416 Thu, 08 Jul 2010 10:06:42 +0100 3736416 A Practical Synthesis of the PDE4 Inhibitor, KW-4490 http://www.medworm.com/index.php?rid=3951470&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2F0qMpKYhLbfk%2Fop1001287 Organic Process Research & DevelopmentDOI: 10.1021/op1001287 (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3951470 Thu, 08 Jul 2010 04:35:48 +0100 3951470 Development of a Dynamic Kinetic Resolution for the Isolation of an Intermediate in the Synthesis of Casopitant Mesylate: Application of QbD Principles in the Definition of the Parameter Ranges, Issues in the Scale-Up and Mitigation Strategies http://www.medworm.com/index.php?rid=3951471&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2F1Xdb26eQ9yc%2Fop100121s Organic Process Research & DevelopmentDOI: 10.1021/op100121s (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3951471 Thu, 08 Jul 2010 04:35:09 +0100 3951471 Book Review of Practical Methods for Biocatalysis and Biotransformations http://www.medworm.com/index.php?rid=3951472&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FAL0uW3-wn0w%2Fop100183p Organic Process Research & DevelopmentDOI: 10.1021/op100183p (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3951472 Wed, 07 Jul 2010 19:30:03 +0100 3951472 A Novel Scalable Synthesis of Pramipexole http://www.medworm.com/index.php?rid=3736417&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop1000989%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3736417 Wed, 07 Jul 2010 16:22:57 +0100 3736417 Overall Synthesis of GSK356278: Quick Delivery of a PDE4 Inhibitor Using a Fit-for-Purpose Approach http://www.medworm.com/index.php?rid=3721269&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop1001148%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3721269 Fri, 02 Jul 2010 10:06:19 +0100 3721269 Some Items of Interest to Process R&D Chemists and Engineers http://www.medworm.com/index.php?rid=3717703&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100166w%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3717703 Thu, 01 Jul 2010 10:14:57 +0100 3717703 Improved Process for the Preparation of 1-Benzhydrylazetidin-3-ol: Development of an Efficient Synthesis and Identification of Process-related Impurities and/or Intermediates http://www.medworm.com/index.php?rid=3709772&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100100y%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3709772 Tue, 29 Jun 2010 10:10:44 +0100 3709772 Identification of a Manufacturing Route of Novel CRF-1 Antagonists Containing a 2,3-Dihydro-1H-pyrrolo[2,3-b]pyridine Moiety http://www.medworm.com/index.php?rid=3709773&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100147h%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3709773 Mon, 28 Jun 2010 15:23:42 +0100 3709773 Development of a Pilot-Plant-Scale Synthesis of an Alkylated Dihydrobenzothiadiazole S,S-Dioxide: Incorporation of a Late-Stage Mitsunobu Reaction† http://www.medworm.com/index.php?rid=3701505&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100113j%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3701505 Sat, 26 Jun 2010 10:07:48 +0100 3701505 Investigation into the Formation of the Genotoxic Impurity Ethyl Besylate in the Final Step Manufacturing Process of UK-369,003-26, a Novel PDE5 Inhibitor http://www.medworm.com/index.php?rid=3701506&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100141g%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3701506 Fri, 25 Jun 2010 12:57:40 +0100 3701506 Efficient Synthesis of Imidazoles from Aldehydes and 1,2-Diketones under Superheating Conditions by Using a Continuous Flow Microreactor System under Pressure http://www.medworm.com/index.php?rid=3698776&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100058h%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3698776 Fri, 25 Jun 2010 10:06:54 +0100 3698776 Development of a New Synthesis for the Large-Scale Preparation of Triple Reuptake Inhibitor (−)-GSK1360707 http://www.medworm.com/index.php?rid=3690140&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100139f%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3690140 Wed, 23 Jun 2010 10:10:22 +0100 3690140 Scaling Up Attrition-Enhanced Deracemization by Use of an Industrial Bead Mill in a Route to Clopidogrel (Plavix) http://www.medworm.com/index.php?rid=3690141&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop1001116%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3690141 Tue, 22 Jun 2010 13:51:28 +0100 3690141 Selection and Development of the Manufacturing Route for EP1 Antagonist GSK269984B http://www.medworm.com/index.php?rid=3686379&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100072y%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3686379 Tue, 22 Jun 2010 10:07:14 +0100 3686379 Special Feature Section: Potential Genotoxic Impurities http://www.medworm.com/index.php?rid=3686380&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100165z%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3686380 Mon, 21 Jun 2010 12:36:36 +0100 3686380 Development of a Control Strategy for a Defluorinated Analogue in the Manufacturing Process of Casopitant Mesylate http://www.medworm.com/index.php?rid=3675736&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop1000836%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3675736 Fri, 18 Jun 2010 10:07:35 +0100 3675736 Formation of (S)-5-Cyclohexyl-5-phenyl-1,3-dioxolane-2,4-dione: A Key Intermediate in the Synthesis of (S)-Oxybutynin Hydrochloride† http://www.medworm.com/index.php?rid=3670617&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100021w%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3670617 Thu, 17 Jun 2010 10:14:22 +0100 3670617 Risk Assessment and Safety Evaluation Study for Ozonolysis of β-Pinene: Raw Material of a Novel Prostaglandin D2 Receptor Antagonist S-5751 http://www.medworm.com/index.php?rid=3665198&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100065d%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3665198 Wed, 16 Jun 2010 10:06:32 +0100 3665198 A Scalable Synthesis of a 1,7-Naphthyridine Derivative, a PDE-4 Inhibitor http://www.medworm.com/index.php?rid=3665199&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100124x%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3665199 Tue, 15 Jun 2010 14:52:33 +0100 3665199 Genotoxic Impurities: From Structural Alerts to Qualification http://www.medworm.com/index.php?rid=3665200&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100118e%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3665200 Tue, 15 Jun 2010 13:38:11 +0100 3665200 A New and Efficient Synthesis of 6-[(5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]non-7-yl]nicotinic Acid, a Potent LFA-1/ICAM Inhibitor http://www.medworm.com/index.php?rid=3661991&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100104z%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3661991 Tue, 15 Jun 2010 10:07:00 +0100 3661991 Risk Assessment and Safety Evaluation Study for Ozonolysis of β-Pinene: Raw Material of a Novel Prostaglandin D2 Receptor Antagonist S-5751 http://www.medworm.com/index.php?rid=3951475&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Facs%2Foprdfk%2F%7E3%2FO5l8CwhiDjo%2Fop100065d Organic Process Research & DevelopmentDOI: 10.1021/op100065d (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3951475 Tue, 15 Jun 2010 04:23:26 +0100 3951475 Large-Scale Polycondensation of Lactic Acid Using Microwave Batch Reactors http://www.medworm.com/index.php?rid=3655176&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop900325e%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3655176 Sat, 12 Jun 2010 10:07:20 +0100 3655176 Highly Diastereoselective Hydrogenation of Imines by a Bimetallic Pd−Cu Heterogeneous Catalyst http://www.medworm.com/index.php?rid=3651693&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop1001325%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3651693 Fri, 11 Jun 2010 10:06:33 +0100 3651693 An Efficient Method for Removal of Residual Palladium from Organic Solution of Faropenem Sodium in the Pd(II)-Catalyzed Cleavage of Allyl Faropenem http://www.medworm.com/index.php?rid=3651694&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100094p%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3651694 Thu, 10 Jun 2010 11:48:07 +0100 3651694 A Commercial Continuous Flow Microwave Reactor Evaluated for Scale-Up http://www.medworm.com/index.php?rid=3651695&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100082w%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3651695 Thu, 10 Jun 2010 11:47:27 +0100 3651695 The Synthesis of GV143253A: A Case Study for the Use of Analytical and Statistical Tools to Elucidate the Reaction Mechanism and to Optimize the Process http://www.medworm.com/index.php?rid=3644011&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100097c%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3644011 Wed, 09 Jun 2010 10:05:52 +0100 3644011 Development of an Efficient Large-Scale Synthesis for a 4H-imidazo[5,1-c][1,4]benzoxazine-3-carboxamide Derivative for Depression and Anxiety http://www.medworm.com/index.php?rid=3640016&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100103v%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3640016 Tue, 08 Jun 2010 10:07:28 +0100 3640016 Risk Assessment of Genotoxic Impurities in Marketed Compounds Administered over a Short-Term Duration: Applications to Oncology Products and Implications for Impurity Control Limits http://www.medworm.com/index.php?rid=3640017&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop1000226%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3640017 Mon, 07 Jun 2010 13:16:08 +0100 3640017 Total Synthesis of Hematoporphyrin and Protoporphyrin: A Conceptually New Approach http://www.medworm.com/index.php?rid=3628760&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100036c%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3628760 Fri, 04 Jun 2010 10:05:42 +0100 3628760 Process Development and Large-Scale Synthesis of a c-Met Kinase Inhibitor http://www.medworm.com/index.php?rid=3624482&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100101q%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3624482 Thu, 03 Jun 2010 10:08:15 +0100 3624482 Review of U.S. Patents in the Field of Organic Process Development Published During February and March 2010 http://www.medworm.com/index.php?rid=3624483&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100134a%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3624483 Wed, 02 Jun 2010 12:58:00 +0100 3624483 Process Research and Development of a MTP Inhibitor: Another Case of Disappearing Polymorphs upon Scale-up http://www.medworm.com/index.php?rid=3609698&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100115u%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3609698 Fri, 28 May 2010 10:06:51 +0100 3609698 Development of a Kilogram-Scale Asymmetric Synthesis of a Potent DP Receptor Antagonist http://www.medworm.com/index.php?rid=3602672&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100008m%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3602672 Wed, 26 May 2010 12:58:33 +0100 3602672 Green Chemistry Articles of Interest to the Pharmaceutical Industry http://www.medworm.com/index.php?rid=3602671&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop100116s%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3602671 Wed, 26 May 2010 10:06:56 +0100 3602671 Application of the QbD Principles in the Development of the Casopitant Mesylate Manufacturing Process. Process Research Studies for the Definition of the Control Strategy of some Drug Substance-CQAs for Stages 2a, 2b, and 2c http://www.medworm.com/index.php?rid=3602673&cid=s_33717_59_f&fid=33717&url=http%3A%2F%2Fpubs.acs.org%2Fdoi%2Fabs%2F10.1021%2Fop1000622%3Fai%3D55f%26af%3DR Organic Process Research & Development, Volume 0, Issue 0, Articles ASAP (As Soon As Publishable). (Source: Organic Process Research) Organic Process Research journals http://www.medworm.com/rss/comments.php?id=3602673 Tue, 25 May 2010 18:40:50 +0100 3602673