MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Osteoporosis International' source. Thu, 09 Feb 2012 00:02:41 +0100 http://www.medworm.com/index.php?rid=5669127&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F285876000247h525%2F Conclusions  Pelvic fractures are associated with high rates of hospitalisation and mortality. Given this, further work is required to identify the optimal post-fracture therapeutic strategy to improve outcomes in this elderly patient group. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00198-012-1907-zAuthors D. Prieto-Alhambra, Oxford NIHR Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Windmill Road, Headington, Oxford OX3 7LD, UKF. F. Avilés, Institut Català de la Salut—IDIAP Jordi Gol i Gurina, Barcelona, SpainA. Judge, Oxford NIHR Musculoskeletal Biomedical Research Unit, Nuffield Department of Orthopaedics, Rheumatology and Musculoske... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5669127 Mon, 06 Feb 2012 19:37:21 +0100 5669127 http://www.medworm.com/index.php?rid=5661138&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff5q5t7p2632044g5%2F Content Type Journal ArticleCategory ErratumPages 1-2DOI 10.1007/s00198-011-1887-4Authors S. Ishii, Geriatric Research, Education and Clinical Center (GRECC), VA Greater Los Angeles Healthcare System, 11301 Wilshire Blvd, Building 220, Room 302, Los Angeles, CA 90073, USAJ. A. Cauley, Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 130 DeSoto Street, A524 Crabtree, Pittsburgh, PA 15260, USAG. A. Greendale, Department of Medicine/Division of Geriatrics, David Geffen School of Medicine at UCLA, 10933 Le Conte Ave, Los Angeles, CA 90095, USAM. E. Danielson, Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 130 DeSoto Street, A524 Crabtree, Pittsburgh, PA 15260, USAN. Safaei Nili, Department of Medicine/Division ... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5661138 Fri, 03 Feb 2012 17:11:21 +0100 5661138 http://www.medworm.com/index.php?rid=5661139&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F75626v577q2696m0%2F Abstract  Osteocytes actively participate in almost every phase of mineral handling by bone. They regulate the mineralisation of osteoid during bone formation, and they are also a major RANKL-producing cell. Osteocytes are thus able to liberate bone mineral by regulating osteoclast differentiation and activity in response to a range of stimuli, including bone matrix damage, bone disuse and mechanical unloading, oestrogen deficiency, high-dose glucocorticoid and chemotherapeutic agents. At least some of these activities may be regulated by the osteocyte-secreted product, sclerostin. There is also mounting evidence that in addition to regulating phosphate homeostasis systemically, osteocytes contribute directly to calcium homeostasis in the mature skeleton. Osteocyte cell dea... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5661139 Thu, 02 Feb 2012 18:14:38 +0100 5661139 http://www.medworm.com/index.php?rid=5661140&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe282416l10p0596q%2F Conclusion  In oldest old nursing home residents, osteoporosis and vertebral fracture were frequently detected. Ten-year fracture probability appeared to be mainly determined by age and clinical risk factors obtained by medical history, rather than by BMD or vertebral fracture. Content Type Journal ArticleCategory Original ArticlePages 1-6DOI 10.1007/s00198-012-1900-6Authors A. Rodondi, Division of Bone Diseases, Department of Medical Specialties, Geneva University Hospitals and Faculty of Medicine, CH–1211 Geneva 14, SwitzerlandT. Chevalley, Division of Bone Diseases, Department of Medical Specialties, Geneva University Hospitals and Faculty of Medicine, CH–1211 Geneva 14, SwitzerlandR. Rizzoli, Division of Bone Diseases, Department of Medical Specialties, Genev... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5661140 Thu, 02 Feb 2012 18:14:36 +0100 5661140 http://www.medworm.com/index.php?rid=5661141&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr1847r3315229162%2F Conclusions  Intravenous bisphosphonate therapy was associated with improvements in back pain and stabilization to improvement in vertebral height ratios of previously fractured vertebral bodies. At the same time, such therapy does not appear to completely prevent the development of new vertebral fractures in this context. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00198-012-1911-3Authors A. M. Sbrocchi, Division of Endocrinology, Children’s Hospital of Eastern Ontario, 401 Smyth Rd., Ottawa, ON, Canada K1H 8L1F. Rauch, Genetics Unit, Shriners Hospital for Children, Montreal, QC, CanadaP. Jacob, Division of Neurology, Children’s Hospital of Eastern Ontario, Ottawa, ON, CanadaA. McCormick, Division of Neurology, Children’s Hospita... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5661141 Thu, 02 Feb 2012 06:55:23 +0100 5661141 http://www.medworm.com/index.php?rid=5661143&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv6vv75547777w020%2F Conclusions  Among CKD patients not yet requiring renal replacement therapy, BMD by DXA is able to discriminate fracture status. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00198-012-1908-yAuthors S. A. Jamal, Women’s College Research Institute, 790 Bay Street, Suite 725, Toronto, ON M5G 1N8, CanadaA. M. Cheung, Department of Medicine, University of Toronto, Toronto, ON, CanadaS. L. West, Women’s College Research Institute, 790 Bay Street, Toronto, ON M5G 1N8, CanadaC. E. Lok, Department of Medicine, University of Toronto, Toronto, ON, Canada Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5661143 Wed, 01 Feb 2012 17:14:09 +0100 5661143 http://www.medworm.com/index.php?rid=5661142&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F5l8431351w661635%2F Conclusions  If the association estimated in our study is causal, our results provide evidence that some hip fracture-related deaths could be prevented by improved patient access to appropriate and timely hospital care in the context of a developing country. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00198-012-1917-xAuthors E. I. O. Vidal, Internal Medicine Department, Universidade Estadual Paulista (UNESP), Botucatu, BrazilD. C. Moreira-Filho, Preventive and Social Medicine Department, Universidade Estadual de Campinas (UNICAMP), Campinas, BrazilR. S. Pinheiro, Public Health Studies Institute, Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, BrazilR. C. Souza, Health Sciences Center, Fundação Serra dos Órgãos, Teresop... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5661142 Wed, 01 Feb 2012 17:14:09 +0100 5661142 http://www.medworm.com/index.php?rid=5661144&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg34l812407867w87%2F Conclusion  In older men, poor physical performance is associated with lower hip aBMD and poor bone microarchitecture (mainly at the distal tibia). Content Type Journal ArticleCategory Original ArticlePages 1-12DOI 10.1007/s00198-012-1906-0Authors S. Blaizot, INSERM UMR 1033, Université de Lyon, Lyon, FranceS. Boutroy, INSERM UMR 1033, Université de Lyon, Lyon, FranceN. Vilayphiou, INSERM UMR 1033, Université de Lyon, Lyon, FranceS. Boonen, Division of Gerontology and Geriatrics and Center for Musculoskeletal Research, Division of Geriatric Medicine and Center for Metabolic Bone Diseases, Leuven University Hospital Department of Internal Medicine, Leuven, BelgiumR. Chapurlat, INSERM UMR 1033, Université de Lyon, Lyon, FranceP. Szulc, INSERM UMR 1033, Université d... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5661144 Tue, 31 Jan 2012 07:05:11 +0100 5661144 http://www.medworm.com/index.php?rid=5661145&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F0141266p00117930%2F Abstract  An operational definition of musculoskeletal decline in older people is needed to allow development of interventions for prevention or treatment, as was developed for the treatment of osteoporosis. Frailty and sarcopenia are linked, but distinct, correlates of musculoskeletal aging that have many causes, including age-related changes in body composition, inflammation, and hormonal imbalance. With the emergence of a number of exciting candidate therapies to retard the loss of muscle mass with aging, the derivation of a consensual definition of sarcopenia and physical frailty becomes an urgent priority. Although several consensual definitions have been proposed, these require clinical validation. An operational definition, which might provide a threshold for treatme... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5661145 Tue, 31 Jan 2012 07:05:09 +0100 5661145 http://www.medworm.com/index.php?rid=5661147&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F72k55kg44j745931%2F Abstract  Bone remodeling is essential for adult bone homeostasis. The failure of this process often leads to the development of osteoporosis, a present major global health concern. The most important factor that affects normal bone remodeling is the tightly controlled and orchestrated regulation of osteoblasts and osteoclasts. The present review summarized the recent discoveries related to osteoblast regulation from several signals, including transforming growth factor-β, bone morphogenetic proteins, Wnt signal, Notch, Eph–Ephrin interaction, parathyroid hormone/parathyroid hormone-related peptide, and the leptin–serotonin–sympathetic nervous systemic pathway. The awareness of these mechanisms will facilitate further research that explores bone remodeling and osteop... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5661147 Tue, 31 Jan 2012 07:05:08 +0100 5661147 http://www.medworm.com/index.php?rid=5661146&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ffv27rt5475678w34%2F Content Type Journal ArticleCategory Letter to the EditorPages 1-2DOI 10.1007/s00198-012-1905-1Authors K. Michaëlsson, Department of Surgical Sciences, Uppsala University, SE 751 85 Uppsala, SwedenJ. Schilcher, Department of Experimental and Clinical Medicine, Faculty of Health Science, Linköping University, SE 581 85 Linköping, SwedenP. Aspenberg, Department of Experimental and Clinical Medicine, Faculty of Health Science, Linköping University, SE 581 85 Linköping, Sweden Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5661146 Tue, 31 Jan 2012 07:05:08 +0100 5661146 http://www.medworm.com/index.php?rid=5650900&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F6q75776213538131%2F Content Type Journal ArticleCategory Letter to the EditorPages 1-2DOI 10.1007/s00198-012-1910-4Authors M. F. McCarty, NutriGuard Research, Inc., Encinitas, CA 92024, USA Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5650900 Fri, 27 Jan 2012 17:56:37 +0100 5650900 http://www.medworm.com/index.php?rid=5650901&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl3g221680qk86358%2F Conclusion  Together, these data show that dietary fat is the most significant positive predictor of TFCA which may have implications for dietary intake for non-obese individuals who are more likely to have lower and potentially compromised Ca absorption. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00198-012-1901-5Authors S. A. Shapses, Department of Nutritional Sciences, Rutgers University, 96 Lipman Drive, New Brunswick, NJ 08901-8525, USAD. Sukumar, Department of Nutritional Sciences, Rutgers University, 96 Lipman Drive, New Brunswick, NJ 08901-8525, USAS. H. Schneider, Department of Endocrinology and Metabolism, University of Medicine and Dentistry at New Jersey, New Brunswick, NJ 08901, USAY. Schlussel, Department of Nutritional Sci... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5650901 Fri, 27 Jan 2012 06:51:47 +0100 5650901 http://www.medworm.com/index.php?rid=5650902&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F875n6x053282u7h1%2F Conclusions  Daily consumption of milk containing 250 mg calcium over 18 months prevents BMD loss at the hip and the femoral neck in postmenopausal Chinese women. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00198-012-1895-zAuthors J.-C. Gui, Department of Nuclear Medicine, Huashan Hospital, Fudan University, 12 Wulumuqi Zhong Rd, Shanghai, 200040 People’s Republic of ChinaJ. R. Brašić, Division of Nuclear Medicine, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, USAX.-D. Liu, Department of Nuclear Medicine, Huashan Hospital, Fudan University, 12 Wulumuqi Zhong Rd, Shanghai, 200040 People’s Republic of ChinaG.-Y. Gong, Technical Center,... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5650902 Thu, 26 Jan 2012 16:44:57 +0100 5650902 http://www.medworm.com/index.php?rid=5650903&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F8454851gm7452218%2F Abstract  Alendronate is a widely used bisphosphonate in the treatment of osteoporosis. Although it has been proven to be a very useful drug, it has some side effects as well. In this paper, we describe a case of nephrotic syndrome due to alendronate administration. A 36-year-old man was admitted to the nephrology outpatient clinic with widespread edema 4 months after initiation of alendronate. He had a 13-kg weight gain within a 2-week period. He had no clinical or laboratory problems apart from osteoporosis, which was the indication for initiation of the drug. Physical examination at admission was unremarkable, but for nephrotic edema. Laboratory studies revealed nephrotic range proteinuria (13.5 g/day), normal renal function, hypoalbuminemia (1.7 g/dl), and... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5650903 Wed, 25 Jan 2012 18:07:44 +0100 5650903 http://www.medworm.com/index.php?rid=5639762&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu27422h2g243288n%2F Conclusion  An electronic medical record intervention without electronic reminders created with physician input achieves an increase in calcium supplementation but fails to increase diagnosis or treatment for osteoporosis at the time of hospitalization for a fragility fracture. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s00198-011-1866-9Authors B. J. Edwards, Bone Health and Osteoporosis Center, Medicine, Feinberg School of Medicine, Northwestern University, 645 North Michigan, Suite 630, Chicago, IL 60611, USAA. D. Bunta, Bone Health and Osteoporosis Center, Department of Orthopaedic Surgery, Feinberg School of Medicine, Northwestern University, Chicago, IL, USAJ. Anderson, Northwestern Memorial Hospital, Chicago, IL, USAA. Bobb, Nort... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5639762 Tue, 24 Jan 2012 18:09:41 +0100 5639762 http://www.medworm.com/index.php?rid=5639764&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg67pln062pv68575%2F Conclusions  This study does not support a significant role for PUFA intake in the prevention of hip fractures, although low total PUFA, n-6 PUFA, or linoleic acid intakes may increase the risk in women. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s00198-012-1903-3Authors J. K. Virtanen, Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio Campus, P.O. Box 1627, 70211 Kuopio, FinlandD. Mozaffarian, Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USAW. C. Willett, Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USAD. Feskanich, Channing Laboratory, Department of Medicine, Brigham and Women’s Hospital and Ha... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5639764 Tue, 24 Jan 2012 07:26:51 +0100 5639764 http://www.medworm.com/index.php?rid=5639763&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F933823w2p80422l3%2F Conclusions  The peri-cement halo was found to be associated with vertebral recollapse, this sign likely represents a poor prognostic factor after vertebral augmentation for osteoporotic compression fractures. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00198-012-1896-yAuthors K. H. Kim, Department of Neurosurgery, Spine and Spinal Cord Institute, Gangnam Severance Hospital, Yonsei University College of Medicine, 712 Eongu-ro, Gangnam-gu, Seoul, 135-720 KoreaS. U. Kuh, Department of Neurosurgery, Spine and Spinal Cord Institute, Gangnam Severance Hospital, Yonsei University College of Medicine, 712 Eongu-ro, Gangnam-gu, Seoul, 135-720 KoreaJ. Y. Park, Department of Neurosurgery, Spine and Spinal Cord Institute, Gangnam Severance Hospital... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5639763 Tue, 24 Jan 2012 07:26:51 +0100 5639763 http://www.medworm.com/index.php?rid=5639766&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F0754828832806p24%2F Conclusion  The ESCEO working group recommends that all AI-treated women should be evaluated for fracture risk. Besides general recommendations, zoledronic acid 4 mg i.v. every 6 months, denosumab s.c., or possibly oral bisphosphonates should be administered for the entire period of AI treatment to all osteoporotic women (T-score hip/spine <−2.5 or ≥1 prevalent fragility fracture), to women aged ≥75 irrespective of BMD, and to patients with T-score <−1.5 + ≥1 clinical risk factor or T-score <−1.0 + ≥2 clinical risk factors. Alternatively, therapy could be considered in patients with a FRAX-determined 10-year hip fracture probability ≥3%. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s00198-011-1... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5639766 Tue, 24 Jan 2012 07:26:50 +0100 5639766 http://www.medworm.com/index.php?rid=5639765&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F8031j052v4624h52%2F Conclusion  Patients who received bisphosphonate therapy were associated with a lower risk of stroke during a 2-year follow-up period. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00198-012-1894-0Authors J.-H. Kang, Department of Physical Medicine and Rehabilitation, School of Medicine, College of Medicine, Taipei Medical University, Taipei, TaiwanJ. J. Keller, School of Medical Laboratory Sciences and Biotechnology, Taipei Medical University, Taipei, TaiwanH.-C. Lin, School of Health Care Administration, College of Medicine, Taipei Medical University, 250 Wu-Hsing St, Taipei, 110 Taiwan Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5639765 Tue, 24 Jan 2012 07:26:50 +0100 5639765 http://www.medworm.com/index.php?rid=5621534&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F9376103xtx841218%2F Conclusion  Aging is associated with considerable declines in proximal humeral bone health which, when coupled with a traumatic event such as a fall, may contribute to osteoporotic fracture at this site. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00198-012-1893-1Authors S. M. Mantila Roosa, Center for Translational Musculoskeletal Research, School of Health and Rehabilitation Sciences, Indiana University, Indianapolis, IN, USAA. L. Hurd, Center for Translational Musculoskeletal Research, School of Health and Rehabilitation Sciences, Indiana University, Indianapolis, IN, USAH. Xu, Department of Biostatistics, Indiana University School of Medicine, Indianapolis, IN, USAR. K. Fuchs, Center for Translational Musculoskeletal Research, School... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5621534 Thu, 19 Jan 2012 06:51:50 +0100 5621534 http://www.medworm.com/index.php?rid=5611824&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq6u503wv2807700r%2F Conclusions  The incidence of hip fractures in women in Oslo has decreased significantly during the last decade and is now at a lower level than in 1978/1979. This reduction was not evident in men. The incidence of hip fractures in Oslo is, however, still the highest in the world. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00198-011-1888-3Authors R. Ø. Støen, Department of Orthopaedics, Oslo University Hospital, Ullevål, 0424 Oslo, NorwayL. Nordsletten, Department of Orthopaedics, Oslo University Hospital, Ullevål, 0424 Oslo, NorwayH. E. Meyer, Division of Epidemiology, Department of Chronic Diseases, Norwegian Institute of Public Health, Oslo, NorwayJ. F. Frihagen, Department of Orthopaedics, Oslo University Hospital, Ullevål, 04... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5611824 Sat, 14 Jan 2012 06:55:16 +0100 5611824 http://www.medworm.com/index.php?rid=5599800&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F173253mk02vq3221%2F Conclusion  Self-reported recreational levels of physical activity positively influence BMD in young adult women but to maximize BMD gains, regular, high-impact exercise is required. Enjoyment of exercise contributes to regularity of exercising which has short- and long-term implications for bone health. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s00198-011-1886-5Authors M. Callréus, Department of Orthopaedics, Lund University, Skåne University Hospital, 205 02 Malmö, SwedenF. McGuigan, Department of Orthopaedics, Lund University, Skåne University Hospital, 205 02 Malmö, SwedenK. Ringsberg, Department of Orthopaedics, Lund University, Skåne University Hospital, 205 02 Malmö, SwedenK. Åkesson, Department of Orthopaedics, Lund Un... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5599800 Fri, 13 Jan 2012 16:57:26 +0100 5599800 http://www.medworm.com/index.php?rid=5599802&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F7440qu46p4322016%2F Conclusions  Greater skeletal growth and BMI gain in utero and during infancy are associated with higher peak BMC, and greater BMI gain in childhood and adolescence is associated with higher peak aBMD and BMAD. These associations are mediated by the attainment of adult height and BMI, respectively. Content Type Journal ArticleCategory Original ArticlePages 1-13DOI 10.1007/s00198-011-1857-xAuthors N. Tandon, Department of Endocrinology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, IndiaC. H. D. Fall, MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UKC. Osmond, MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton, UKH. P. S. Sachdev, Sitaram Bhartia Institute of Science and Research, New Delhi, IndiaD. ... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5599802 Thu, 12 Jan 2012 06:41:06 +0100 5599802 http://www.medworm.com/index.php?rid=5599801&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff027651122uv2354%2F Conclusions  Patients with a mean 25(OH)D ≥33 ng/ml had a substantially greater likelihood of maintaining bisphosphonate response. This threshold level of 25(OH)D is higher than that considered adequate by the Institute of Medicine, arguing that higher levels may be required for specific therapeutic outcomes. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00198-011-1868-7Authors A. S. Carmel, Department of Internal Medicine, Weill Cornell Medical College, 505 East 68th Street, New York, NY 10021, USAA. Shieh, Department of Internal Medicine, Weill Cornell Medical College, 505 East 68th Street, New York, NY 10021, USAH. Bang, Division of Biostatistics and Epidemiology, Department of Public Health, Weill Cornell Medical College, 402 E... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5599801 Thu, 12 Jan 2012 06:41:06 +0100 5599801 http://www.medworm.com/index.php?rid=5599803&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm24708245136374w%2F Conclusions  SUV measurements showed the smallest precision error followed by the Patlak method, while the Hawkins method gave the largest error. Measuring a smaller region of interest did not increase the precision error, suggesting that the factor determining the errors may be scanner calibration. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00198-011-1889-2Authors Y. Al-beyatti, Osteoporosis Screening & Research Unit, Guy’s Hospital, King’s College London, 1st Floor, Tower Wing, London, SE1 9RT UKM. Siddique, Osteoporosis Screening & Research Unit, Guy’s Hospital, King’s College London, 1st Floor, Tower Wing, London, SE1 9RT UKM. L. Frost, Osteoporosis Screening & Research Unit, Guy’s Hospital, King’s College London, 1st F... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5599803 Thu, 12 Jan 2012 06:41:02 +0100 5599803 http://www.medworm.com/index.php?rid=5599805&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl876342216j632w0%2F Conclusions  Vitamin D and PA may interact to determine BMC. 25(OH)D sufficiency levels improve bone mass only in active adolescents, or PA has a positive influence on BMC in individuals with replete vitamin D levels. Content Type Journal ArticleCategory Original ArticlePages 1-11DOI 10.1007/s00198-011-1884-7Authors J. Valtueña, Department of Health and Human Performance, Faculty of Physical Activity and Sport Sciences–INEF, Technical University of Madrid, C/ Martín Fierro, 7, 28040 Madrid, SpainL. Gracia-Marco, GENUD (Growth, Exercise, Nutrition and Development) Research Group, Zaragoza, SpainG. Vicente-Rodríguez, GENUD (Growth, Exercise, Nutrition and Development) Research Group, Zaragoza, SpainM. González-Gross, Department of Health and Human Performance, Fac... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5599805 Thu, 12 Jan 2012 06:41:01 +0100 5599805 http://www.medworm.com/index.php?rid=5599804&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F546226622k382x50%2F Conclusions  Trabecular level stresses associated with microdamage do not continue to decrease with prolonged alendronate treatment. Changes in mineralization may account for these findings. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00198-011-1875-8Authors J. O. Green, Parker H. Petit Institute for Bioengineering and Bioscience and George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, 315 Ferst Drive, Atlanta, GA 30332-0405, USAT. Diab, Parker H. Petit Institute for Bioengineering and Bioscience and George W. Woodruff School of Mechanical Engineering, Georgia Institute of Technology, 315 Ferst Drive, Atlanta, GA 30332-0405, USAM. R. Allen, Department of Anatomy and Cell Biology, Indiana University School... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5599804 Thu, 12 Jan 2012 06:41:01 +0100 5599804 http://www.medworm.com/index.php?rid=5585390&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj238r2134346l6x5%2F Conclusion  We showed that in human MG-63 cells, iron exposure impacts iron metabolism and osteoblast gene expression. HHIPL-2 gene expression modulation may contribute to these alterations. Our results support a role of osteoblast impairment in iron-related osteoporosis. Content Type Journal ArticleCategory Original ArticlePages 1-11DOI 10.1007/s00198-011-1871-zAuthors M. Doyard, INSERM, UMRU991, CHU Pontchaillou, 35033 Rennes Cedex, FranceN. Fatih, INSERM, UMRU991, CHU Pontchaillou, 35033 Rennes Cedex, FranceA. Monnier, CNRS UMR6061, Institut de Génétique et Développement, Université de Rennes, UEB, IFR140, 35043 Rennes, FranceM. L. Island, INSERM, UMRU991, CHU Pontchaillou, 35033 Rennes Cedex, FranceM. Aubry, Plateforme Génomique Santé Biogenouest®, 35043 Re... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5585390 Wed, 11 Jan 2012 17:56:53 +0100 5585390 http://www.medworm.com/index.php?rid=5585392&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv0339t7l04lr3820%2F Conclusion  Compared to the RCP strategy, the FRAX-based NOGG strategy uses BMD resources more efficiently with lower acquisition costs and lower costs per hip fracture averted. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00198-011-1864-yAuthors H. Johansson, Consulting Statisticians, Gothenburg, SwedenJ. A. Kanis, WHO Collaborating Centre for Metabolic Bone Diseases, University of Sheffield, Sheffield, UKA. Oden, Consulting Statisticians, Gothenburg, SwedenJ. Compston, Department of Medicine, University of Cambridge School of Clinical Medicine and Addenbrooke’s NHS Trust, Cambridge, UKE. McCloskey, WHO Collaborating Centre for Metabolic Bone Diseases, University of Sheffield, Sheffield, UK Journal Osteoporosis InternationalOnli... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5585392 Wed, 11 Jan 2012 06:56:44 +0100 5585392 http://www.medworm.com/index.php?rid=5585391&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd2g1756553j8257j%2F Conclusion  Our findings conclude that lifelong physical activity with continuation into old age (≥65 years) best maintains better bone health in the elderly. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s00198-011-1874-9Authors N. J. Rianon, Family and Community Medicine, UTHSC Medical School, 6431 Fannin #JJL324, Houston, TX 77030, USAT. F. Lang, Radiology and Biomedical Imaging, UCSF School of Medicine, San Francisco, CA, USAG. Sigurdsson, Division of Endocrinology and Metabolism, Department of Internal Medicine, Landspitali-University Hospital, Reykjavik, IcelandG. Eiriksdottir, Icelandic Heart Association, Kopavogur, IcelandS. Sigurdsson, Icelandic Heart Association, Kopavogur, IcelandM. Garcia, Laboratory of Epidemiology, Dem... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5585391 Wed, 11 Jan 2012 06:56:44 +0100 5585391 http://www.medworm.com/index.php?rid=5585393&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl568025237h5m73m%2F Conclusion  We conclude that hemodialysis patients have a marked decreased in cortical density, thickness, and area with significant reduction in trabecular parameters that correlated with the severity of secondary hyperparathyroidism only in women. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00198-011-1890-9Authors A. L. Negri, Instituto de Investigaciones Metabólicas, Universidad del Salvador, Libertad 836 1 piso, Buenos Aires, 1012 ArgentinaE. E. Del Valle, Instituto de Investigaciones Metabólicas, Universidad del Salvador, Libertad 836 1 piso, Buenos Aires, 1012 ArgentinaM. B. Zanchetta, Instituto de Investigaciones Metabólicas, Universidad del Salvador, Libertad 836 1 piso, Buenos Aires, 1012 ArgentinaM. Nobaru, Instituto de Inve... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5585393 Wed, 11 Jan 2012 06:56:43 +0100 5585393 http://www.medworm.com/index.php?rid=5585394&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp5845572720720hm%2F Conclusions  Our data highlights the importance of two large genomic deletions and mutations in the 5′ UTR with respect to patient management and, more critically, to prenatal diagnosis. With the present work, we strongly contribute to the molecular dissection of TCIRG1-deficient ARO and identify several protein residues which are fundamental for proton pump function and could thus be the target of future drugs designed to inhibit osteoclast resorptive activity. Content Type Journal ArticleCategory Short CommunicationPages 1-6DOI 10.1007/s00198-011-1878-5Authors A. Pangrazio, Milan Unit, Institute of Genetic and Biomedical Research (IRGB), National Research Council, 20138 Milan, ItalyM. E. Caldana, Milan Unit, Institute of Genetic and Biomedical Research (IRGB), N... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5585394 Mon, 09 Jan 2012 19:40:07 +0100 5585394 http://www.medworm.com/index.php?rid=5573339&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F052h2q313t517j07%2F Abstract    Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s00198-011-1853-1Authors J. Rawal, Institute for Health and Human Performance, University College London, London, UKK. Eleftheriou, Institute for Health and Human Performance, University College London, London, UKJ. Skipworth, Institute for Health and Human Performance, University College London, London, UKZ. Puthucheary, Institute for Health and Human Performance, University College London, London, UKM. Loosemore, English Institute of Sport, Manchester, UKJ. Payne, Scottish National Advanced Heart Failure Service, Jubilee National Hospital, Clydebank, UKF. Dreno, Centre for Cardiovascular Genetics, University College London, London, UKM. World, Royal Centre for Defense Medicine, Sell... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5573339 Fri, 06 Jan 2012 06:45:00 +0100 5573339 http://www.medworm.com/index.php?rid=5573340&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff1350724623758g3%2F Conclusions  Using a FRAX-based intervention threshold of 15% for both women and men should permit cost-effective access to therapy to patients at high fracture probability based on clinical risk factors and thereby contribute to further reduce the growing burden of osteoporotic fractures in Switzerland. Content Type Journal ArticleCategory Original ArticlePages 1-11DOI 10.1007/s00198-011-1869-6Authors K. Lippuner, Osteoporosis Policlinic, Inselspital, Bern University Hospital and University of Bern, Bern, SwitzerlandH. Johansson, WHO Collaborating Centre for Metabolic Bone Diseases, University of Sheffield Medical School, Sheffield, UKF. Borgström, LIME/MMC, Karolinska Institutet, Stockholm, SwedenJ. A. Kanis, WHO Collaborating Centre for Metabolic Bone Diseases, U... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5573340 Fri, 06 Jan 2012 06:44:58 +0100 5573340 http://www.medworm.com/index.php?rid=5573341&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe4q5h80147130716%2F Conclusions  A method of identifying post-HF surgery patients at various levels (high-, medium-, and low-) of risk for unsuccessful recovery of pre-fracture walking ability has been designed. The method may be useful for clinicians and healthcare administrators to target populations for rehabilitative programs. Content Type Journal ArticleCategory Original ArticlePages 1-12DOI 10.1007/s00198-011-1849-xAuthors G. Bellelli, Department of Clinical and Preventive Medicine, University of Milano-Bicocca, Geriatric Clinic, S. Gerardo Hospital, via Cadore 48, Monza, ItalyM. Noale, CNR, Institute of Neuroscience-Aging Branch, Padova, ItalyF. Guerini, Department of Rehabilitation and Aged Care, Ancelle della Carità Hospital, via Aselli 14, Cremona, ItalyR. Turco, Department o... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5573341 Fri, 06 Jan 2012 06:44:57 +0100 5573341 http://www.medworm.com/index.php?rid=5573342&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl534w6316wxw1m00%2F Abstract  Guidelines for osteoporosis treatment are available; however, these guidelines suggest when to treat patients, without specific recommendations on what drugs to prescribe in various situations. Choice of osteoporosis therapy should be individualized based on consideration of the efficacy, safety, cost, convenience (i.e., dosing regimen and delivery), and other non-osteoporosis-related benefits associated with each agent. Bisphosphonates, administered orally or intravenously, should be considered first-line therapy, particularly in older patients, owing to their efficacy across multiple skeletal sites; however, there are potential short- and long-term safety concerns. Selective estrogen receptor modulators should be considered for younger postmenopausal women at gr... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5573342 Wed, 04 Jan 2012 17:02:17 +0100 5573342 http://www.medworm.com/index.php?rid=5573343&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fbwt1766286237102%2F Conclusion  In terms of the multifactorial etiology of BRONJ, bone formation suppression was noticed in the patients. Based upon this finding, the short-term use of teriparatide might be beneficial to the resolution of BRONJ lesions by improving suppressed bone remodeling. Content Type Journal ArticleCategory Short CommunicationPages 1-5DOI 10.1007/s00198-011-1882-9Authors Y.-D. Kwon, Department of Oral & Maxillofacial Surgery, Kyung Hee University School of Dentistry, Hoegi-dong, Dongdaenum-ku, Seoul, 130-701 Republic of KoreaD.-W. Lee, Department of Oral & Maxillofacial Surgery, Kyung Hee University School of Dentistry, Hoegi-dong, Dongdaenum-ku, Seoul, 130-701 Republic of KoreaB.-J. Choi, Department of Oral & Maxillofacial Surgery, Kyung Hee University School of D... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5573343 Wed, 04 Jan 2012 17:02:13 +0100 5573343 http://www.medworm.com/index.php?rid=5573344&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F0545jt873q17g264%2F Conclusions  Our results suggest POSTN as a candidate gene for BMD variation and vertebral fracture risk. Content Type Journal ArticleCategory Original ArticlePages 1-11DOI 10.1007/s00198-011-1861-1Authors S.-M. Xiao, Department of Medicine, Faculty of Medicine, The University of Hong Kong, Hong Kong, ChinaY. Gao, Department of Medicine, Faculty of Medicine, The University of Hong Kong, Hong Kong, ChinaC.-L. Cheung, Department of Medicine, Faculty of Medicine, The University of Hong Kong, Hong Kong, ChinaC. H. Bow, Department of Medicine, Faculty of Medicine, The University of Hong Kong, Hong Kong, ChinaK.-S. Lau, Department of Medicine, Faculty of Medicine, The University of Hong Kong, Hong Kong, ChinaP. C. Sham, Department of Psychiatry, Faculty of Medicine, The Univ... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5573344 Wed, 04 Jan 2012 07:00:54 +0100 5573344 http://www.medworm.com/index.php?rid=5573345&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F7453441107m52rn1%2F Conclusion  During sunlight deprivation of up to 12 months, serum 25(OH)D levels can be maintained above 50 nmol/L when expeditioners are provided with 50,000 I U at least every alternate month. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00198-011-1858-9Authors S. Iuliano-Burns, Austin Health, University of Melbourne, Parkville, AustraliaJ. Ayton, Australian Antarctic Division, Kingston, AustraliaS. Hillam, Australian Antarctic Division, Kingston, AustraliaG. Jones, University of Tasmania, Menzies Research Institute, Hobart, AustraliaK. King, Austin Health, University of Melbourne, Parkville, AustraliaS. Macleod, Austin Health, University of Melbourne, Parkville, AustraliaE. Seeman, Austin Health, University of Melbourne, Park... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5573345 Wed, 04 Jan 2012 07:00:51 +0100 5573345 http://www.medworm.com/index.php?rid=5573346&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa2g773qp1681tp1g%2F Conclusions  An ethnicity difference in post-fracture care was observed. Further work is needed to elucidate underlying mechanisms for this difference and to determine whether failure to initiate treatment originates with the medical practitioner, the patient, or a combination of both. It is imperative that all residents of Manitoba receive efficacious and equal care post-fracture, regardless of ethnicity. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00198-011-1880-yAuthors W. D. Leslie, Department of Medicine (C5121), University of Manitoba, 409 Tache Avenue, Winnipeg, Manitoba, Canada R2H 2A6S. L. Brennan, Department of Medicine, NorthWest Academic Centre, University of Melbourne, 176 Furlong Road, St Albans, Melbourne, VIC 3021, Aust... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5573346 Tue, 03 Jan 2012 06:44:40 +0100 5573346 http://www.medworm.com/index.php?rid=5545967&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh275016210h88641%2F Conclusion  Among MOST participants, the 25(OH)D thresholds at which no further change in iPTH was observed was approximately 20 ng/ml in African Americans versus approximately 30 ng/ml in Caucasians, suggesting optimal vitamin D levels in Caucasians may not be applicable to African Americans. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00198-011-1877-6Authors N. C. Wright, Department of Epidemiology, University of Alabama at Birmingham, RPHB 523, 1665 University Blvd, Birmingham, AL 35294, USAL. Chen, Division of Clinical Immunology and Rheumatology, University of Alabama at Birmingham, FOT 805, 510 20th Street South, Birmingham, AL 35294, USAJ. Niu, Clinical Epidemiology Research & Training Unit, Boston University School of ... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5545967 Wed, 21 Dec 2011 20:08:38 +0100 5545967 http://www.medworm.com/index.php?rid=5539619&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe4617833107m75m8%2F Conclusion  Over 3 years of training, 150% BW compressive load in upright stance significantly attenuated BMD decline when compared to passive standing or to no standing. High-resolution CT indicated that trabecular architecture was preserved by the 150% BW dose of load. Content Type Journal ArticleCategory Original ArticlePages 1-12DOI 10.1007/s00198-011-1879-4Authors S. Dudley-Javoroski, Physical Therapy and Rehabilitation Science, Carver College of Medicine, The University of Iowa, 1-252 Medical Education Building, Iowa City, IA 52242-1190, USAP. K. Saha, Department of Electrical and Computer Engineering, The University of Iowa, Iowa City, IA 52242-1190, USAG. Liang, Department of Electrical and Computer Engineering, The University of Iowa, Iowa City, IA 5224... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5539619 Tue, 20 Dec 2011 16:43:18 +0100 5539619 http://www.medworm.com/index.php?rid=5539618&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn38j76536h97448h%2F Conclusion  Cortical BD was improved at 1 year and normalized at 2 years in hyperthyroid patients rendered euthyroid with antithyroid medication. Content Type Journal ArticleCategory Original ArticlePages 1-6DOI 10.1007/s00198-011-1867-8Authors N. Numbenjapon, Center for Endocrinology, Diabetes and Metabolism, Department of Pediatrics, Children’s Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA 90027, USAG. Costin, Center for Endocrinology, Diabetes and Metabolism, Department of Pediatrics, Children’s Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, CA 90027, USAP. Pitukcheewanont, Center for Endocrinology, Diabetes and Metabolism, Department of Pediatrics, Chi... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5539618 Tue, 20 Dec 2011 16:43:18 +0100 5539618 http://www.medworm.com/index.php?rid=5539620&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm0115577227r821r%2F Conclusions  This meta-analysis suggested that C677T polymorphism was marginally associated with fracture risk. In addition, this polymorphism was modestly associated with BMD of lumbar spine, femoral neck, total hip, and total body, respectively. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s00198-011-1885-6Authors H. Wang, Department of Orthopedics, Taizhou Municipal Hospital, Taizhou, 318000 ChinaC. Liu, Department of Clinical Laboratory, Taizhou Municipal Hospital, 381 Zhong Shan Dong Road, Taizhou, 318000 China Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5539620 Tue, 20 Dec 2011 16:43:17 +0100 5539620 http://www.medworm.com/index.php?rid=5516553&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg2015x2323j88x88%2F Conclusion  This analysis provides detailed estimation on the risk of fracture in the French population and may help to define therapeutic guidelines. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00198-011-1883-8Authors C. M. Couris, Pole IMER, Hospices Civils de Lyon, Lyon, 69003 FranceR. D. Chapurlat, INSERM Research UMR 1033, Université de Lyon, Hôpital E Herriot, 69437 Lyon, cedex 03, FranceJ. A. Kanis, WHO Collaborating Centre for Metabolic Bone Diseases, University of Sheffield Medical School, Sheffield, UKH. Johansson, WHO Collaborating Centre for Metabolic Bone Diseases, University of Sheffield Medical School, Sheffield, UKN. Burlet, IOF (International Osteoporosis Foundation), Nyon, SwitzerlandP. D. Delmas, INSERM Research UMR ... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5516553 Fri, 16 Dec 2011 16:56:43 +0100 5516553 http://www.medworm.com/index.php?rid=5516552&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fql372773777l4512%2F Conclusion  Although the effects of annual intravenous zoledronate are guaranteed to last for a year, this study shows that only a third of patients agree to second administration. The factors associated with discontinuation were male gender, adverse effects (especially post-infusion syndrome) and under-explanation of intravenous drug. These findings should be of concern to clinicians and indicate that patients should be informed before the administration. Content Type Journal ArticleCategory Original ArticlePages 1-5DOI 10.1007/s00198-011-1881-xAuthors Y.-K. Lee, Department of Orthopaedic Surgery, Seoul National University Bundang Hospital, 166 Gumi-ro, Bundang-Gu, Sungnam-si, Gyeonggi-do 463-707, South KoreaJ.-H. Nho, Department of Orthopaedic Surgery, Seoul Natio... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5516552 Fri, 16 Dec 2011 16:56:43 +0100 5516552 http://www.medworm.com/index.php?rid=5516554&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F55872106581x52x8%2F Conclusions  An inverse relationship exists between BMAT and BMD in African American and Caucasian men and women. The observed ethnic and sex differences between BMAT and BMD in the present study suggest the possibility that the mechanisms regulating the differentiation and proliferation of bone marrow stromal cells may differ in these populations. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00198-011-1873-xAuthors W. Shen, New York Obesity Nutrition Research Center, St. Luke’s-Roosevelt Hospital, New York, NY, USAJ. Chen, New York Obesity Nutrition Research Center, St. Luke’s-Roosevelt Hospital, New York, NY, USAM. Gantz, New York Obesity Nutrition Research Center, St. Luke’s-Roosevelt Hospital, New York, NY, USAM. Punyanitya, Ne... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5516554 Fri, 16 Dec 2011 06:54:05 +0100 5516554 http://www.medworm.com/index.php?rid=5516555&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F510p3465717q6h26%2F Conclusions  Semi-automated morphometry shows high reliability and a substantial agreement with the SQ approach but overestimates the prevalence of fractures. Its role in routine clinical practice is limited because positive results should be reassessed by qualitative or semi-quantitative methods. Content Type Journal ArticleCategory Original ArticlePages 1-6DOI 10.1007/s00198-011-1819-3Authors J. Sanfélix-Genovés, Health Services Research Unit, Centro Superior de Investigación en Salud Pública (CSISP), Avda. Cataluña 21, 46020 Valencia, SpainE. Arana, Red Española de Investigadores de la Espalda, Fundación Instituto de Investigación en Servicios de Salud, Valencia, SpainG. Sanfélix-Gimeno, Health Services Research Unit, Centro Superior de Investigación en ... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5516555 Wed, 14 Dec 2011 16:42:33 +0100 5516555 http://www.medworm.com/index.php?rid=5507204&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F1k2n574164224084%2F Conclusions  Although there were no differences in back pain-related endpoints, patients receiving teriparatide had greater skeletal benefit than those receiving risedronate. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s00198-011-1856-yAuthors P. Hadji, Department of Endocrinology, Osteoporosis, and Reproductive Medicine, Philipps-University of Marburg, Marburg, GermanyJ. R. Zanchetta, IDIM, Buenos Aires, ArgentinaL. Russo, CCBR Brazil Clinical Research Center, Rio de Janeiro, BrazilC. P. Recknor, United Osteoporosis Centers, Gainesville, GA, USAK. G. Saag, University of Alabama, Birmingham, AL, USAF. E. McKiernan, Center for Bone Disease, Marshfield Clinic, Marshfield, WI, USAS. L. Silverman, Cedars-Sinai/UCLA and OMC Clinical Research ... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5507204 Mon, 12 Dec 2011 17:13:25 +0100 5507204 http://www.medworm.com/index.php?rid=5507205&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F05202jv867306870%2F Conclusions  The present study demonstrates that administration of C. sinensis at higher doses over an 8-week period can prevent the disuse osteoporosis in rats. It implies that C. sinensis might be an alternative therapy for prevention of disuse-induced osteoporosis also in humans. Content Type Journal ArticleCategory Original ArticlePages 1-11DOI 10.1007/s00198-011-1842-4Authors W. Qi, Department of Orthopaedics, Xijing Hospital, The Fourth Military Medical University, No 15, Changle West Road, Xi’an, 710032 ChinaY.-B. Yan, Department of Orthopaedics, Xijing Hospital, The Fourth Military Medical University, No 15, Changle West Road, Xi’an, 710032 ChinaW. Lei, Department of Orthopaedics, Xijing Hospital, The Fourth Military Medical University, No 15, Changle West ... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5507205 Mon, 12 Dec 2011 17:13:24 +0100 5507205 http://www.medworm.com/index.php?rid=5496649&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp6l3087xj10618h6%2F Conclusion  Differential osteogenic potential and responsiveness to E2 of MSCs were found between postmenopausal women with OP and OA. These results may provide information for clinical application of MSCs in the differential setting of estrogen deficiency. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s00198-011-1859-8Authors W.-J. Jin, Department of Orthopaedic Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, ChinaS.-D. Jiang, Department of Orthopaedic Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, ChinaL.-S. Jiang, Department of Orthopaedic Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, ChinaL.-Y. Dai, Department of Orthopaedi... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5496649 Fri, 09 Dec 2011 17:08:11 +0100 5496649 http://www.medworm.com/index.php?rid=5496650&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff440g8jt1h71hq44%2F Conclusions  Among healthy mid-life women receiving a baseline BMD test, few had low bone mass, supporting the need for guidance about testing. A prediction rule with four risk factors had improved sensitivity over the OST. Further validation is warranted. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00198-011-1862-0Authors G. Hawker, Osteoporosis Research Program, Women’s College Research Institute, Women’s College Hospital, 76 Grenville Street, 8th floor, Room 815, Toronto, ON M5S 1B2, CanadaA. Mendel, Osteoporosis Research Program, Women’s College Research Institute, Women’s College Hospital, 76 Grenville Street, 8th floor, Room 815, Toronto, ON M5S 1B2, CanadaM. A. Lam, Osteoporosis Research Program, Women’s College Research... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5496650 Fri, 09 Dec 2011 17:08:10 +0100 5496650 http://www.medworm.com/index.php?rid=5496651&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Faww2778563055479%2F Conclusions  This is the first follow-up association study of rs7776725 and rs1721400 with BMD. The rs7776725 showed consistent association with BMD at multiple clinically important skeletal sites, which highlighted the potential importance of rs7776725 or linked SNPs for risk of osteoporosis. Further in-depth re-sequencing studies and functional assays are necessary to elucidate the underlying mechanisms. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00198-011-1863-zAuthors L.-S. Zhang, College of Life Sciences and Bioengineering, School of Science, Beijing Jiaotong University, Beijing, 100044 People’s Republic of ChinaH.-G. Hu, College of Life Sciences and Bioengineering, School of Science, Beijing Jiaotong University, Beijing, 10004... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5496651 Thu, 08 Dec 2011 18:22:49 +0100 5496651 http://www.medworm.com/index.php?rid=5496652&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh00h888275h93174%2F Conclusions  Our results might imply that the intervention of RVE retarded bone loss induced by simulated microgravity in humans that was mainly attributed to its anabolic effects. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s00198-011-1839-zAuthors H. Wang, State key Lab of Space Medicine Fundamentals and Application, China Astronaut Research and Training Center, Beijing, People’s Republic of China 100094Y. Wan, State key Lab of Space Medicine Fundamentals and Application, China Astronaut Research and Training Center, Beijing, People’s Republic of China 100094K.-F. Tam, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong, People’s Republic of ChinaS. Ling, State key Lab of Space Medicine Fun... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5496652 Thu, 08 Dec 2011 18:22:48 +0100 5496652 http://www.medworm.com/index.php?rid=5539621&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Feg04t558558h5326%2F Content Type Journal ArticleCategory EditorialPages 1-1DOI 10.1007/s00198-011-1865-xAuthors B. Saccomanni, Orthopaedic and Trauma Surgery, ASL Bari, viale Regina Margherita, 74, 70022 Altamura, BA, Italy Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5539621 Thu, 08 Dec 2011 07:19:20 +0100 5539621 http://www.medworm.com/index.php?rid=5496653&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Feg04t558558h5326%2F Content Type Journal ArticleCategory EditorialPages 1-3DOI 10.1007/s00198-011-1865-xAuthors B. Saccomanni, Orthopaedic and Trauma Surgery, ASL Bari, viale Regina Margherita, 74, 70022 Altamura, BA, Italy Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5496653 Thu, 08 Dec 2011 07:19:20 +0100 5496653 http://www.medworm.com/index.php?rid=5488881&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu6m0h7166nw37566%2F Conclusions  These findings suggest that variation in early exposure to n-3 and n-6 LCPUFA may have potential consequences for bone development and that the effects appear to persist into early childhood. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00198-011-1860-2Authors N. Harvey, MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, SO16 6YD UKD. Dhanwal, MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, SO16 6YD UKS. Robinson, MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton, SO16 6YD UKM. Kim, MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hosp... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5488881 Wed, 07 Dec 2011 17:33:17 +0100 5488881 http://www.medworm.com/index.php?rid=5488882&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fvhg772702403n33p%2F Conclusions  Fracture risk decreased as TPTD adherence and persistence increased for any clinical, vertebral, and non-vertebral fractures. Content Type Journal ArticleCategory Original ArticlePages 1-11DOI 10.1007/s00198-011-1843-3Authors S. Yu, Department of Pharmacy Administration, College of Pharmacy, University of Illinois at Chicago, 833 S. Wood Street Room 241, Chicago, IL 60612, USAR. T. Burge, Global Health Outcomes, Eli Lilly & Company, Indianapolis, IN 46285, USAS. A. Foster, Global Health Outcomes, Eli Lilly & Company, Indianapolis, IN 46285, USAS. Gelwicks, Global Health Outcomes, Eli Lilly & Company, Indianapolis, IN 46285, USAE. S. Meadows, Global Health Outcomes, Eli Lilly & Company, Indianapolis, IN 46285, USA Journal Osteoporosis InternationalOnli... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5488882 Wed, 07 Dec 2011 16:44:32 +0100 5488882 http://www.medworm.com/index.php?rid=5488884&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F26n870h1988v5v67%2F Conclusion  This study demonstrated that variations in kilovoltage peak and table height can be controlled using a calibration phantom scanned at the same energy and height as a foot phantom; however, error due to soft tissue thickness and location of bones within a foot cannot be controlled using a calibration phantom alone. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00198-011-1851-3Authors K. E. Smith, Electronic Radiology Laboratory, Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 South Kingshighway Boulevard, Campus Box 8131, St. Louis, MO 63110, USAB. R. Whiting, Department of Radiology, University of Pittsburgh, Pittsburgh, PA, USAG. G. Reiker, Electronic Radiology Laboratory, Mallinckrodt Insti... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5488884 Tue, 06 Dec 2011 19:09:43 +0100 5488884 http://www.medworm.com/index.php?rid=5488883&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj08rx14116264360%2F Conclusions  Consistent with earlier findings in the peripheral skeleton, cortical vBMD is greater at the hip in Chinese American versus White women. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00198-011-1855-zAuthors M. D. Walker, Department of Medicine, College of Physicians and Surgeons, Columbia University, 630 West 168th Street, PH8 West–864, New York, NY 10032, USAI. Saeed, Department of Radiology and Biomedical Imaging, University of California at San Francisco, San Francisco, CA, USAD. J. McMahon, Department of Medicine, College of Physicians and Surgeons, Columbia University, 630 West 168th Street, PH8 West–864, New York, NY 10032, USAJ. Udesky, Department of Medicine, College of Physicians and Surgeons, Columbia University,... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5488883 Tue, 06 Dec 2011 19:09:43 +0100 5488883 http://www.medworm.com/index.php?rid=5488885&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fht3614l3w4w62466%2F Conclusions  BMD precision errors were lower than those for trabecular architecture and cortical porosity. Motion artifacts remain a challenge, particularly at the forearm. Quality grading remains subjective, and more objective evaluation methods are needed. Precision in the context of a multicenter clinical trial, with centralized training and scan analysis, was comparable to single-center results previously reported. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00198-011-1829-1Authors K. Engelke, Synarc Inc., Lübecker Str. 128, 22087 Hamburg, GermanyB. Stampa, Synarc Inc., Lübecker Str. 128, 22087 Hamburg, GermanyW. Timm, Synarc Inc., Lübecker Str. 128, 22087 Hamburg, GermanyB. Dardzinski, Merck Sharp & Dohme Corp., Whitehouse Stat... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5488885 Tue, 06 Dec 2011 07:00:54 +0100 5488885 http://www.medworm.com/index.php?rid=5470541&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj7346822684x3073%2F Conclusions  Cortical bone reacts promptly to reinstitution of GH beyond the attainment of final height by increasing the cortical thickness through endosteal bone growth. This leads to a higher peak bone mass and may reduce the risk of cortical bone fragility later in life. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00198-011-1854-0Authors L. Hyldstrup, Department of Endocrinology (541), Hvidovre University Hospital, DK-2650 Hvidovre, DenmarkG. S. Conway, Department of Endocrinology and Diabetes, University College London Hospitals, London, UKK. Racz, 2nd Department of Medicine, Semmelweis University, Budapest, HungaryA. Keller, Children’s Hospital, University of Leipzig, Leipzig, GermanyP. Chanson, Service d’Endocrinologie et des... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5470541 Tue, 29 Nov 2011 22:18:41 +0100 5470541 http://www.medworm.com/index.php?rid=5470542&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2534425551316887%2F Conclusions  Long-term treatment with strontium ranelate is associated with sustained increases in BMD over 10 years, with a good safety profile. Our results also support the maintenance of antifracture efficacy over 10 years with strontium ranelate. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00198-011-1847-zAuthors J-Y. Reginster, Department of Public Health and Health Economics, University of Liège, Liège, BelgiumJ-M. Kaufman, Ghent University Hospital, Ghent, BelgiumS. Goemaere, Ghent University Hospital, Ghent, BelgiumJ. P. Devogelaer, St-Luc University Hospital, Université catholique de Louvain, UCL 5390, 1200 Brussels, BelgiumC. L. Benhamou, Unité INSERM U658, Rheumatology Department, CHR d’Orléans, Orléans, Fran... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5470542 Tue, 29 Nov 2011 22:18:38 +0100 5470542 http://www.medworm.com/index.php?rid=5460231&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft2l81148260274h4%2F Conclusion  AGS causes increased product substitution which appears to be associated with reduced treatment persistence. Poor health outcomes and associated costs due to forgone drug exposure should be taken into account in the design and evaluation of policies implemented to encourage utilisation of generic medicines. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00198-011-1850-4Authors O. Ström, Medical Management Centre, Department of Learning, Informatics, Management and Ethics, Karolinska Institutet, Berzelius väg 3, 171 77 Stockholm, SwedenE. Landfeldt, OptumInsight, Stockholm, Sweden Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5460231 Sat, 26 Nov 2011 06:40:11 +0100 5460231 http://www.medworm.com/index.php?rid=5460230&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F33t5712011u12285%2F Conclusion  The Dutch FRAX tool is the first fracture prediction model that has been calibrated to the total Dutch population, using nationwide incidence rates for hip fracture and mortality rates. It is based on the original FRAX methodology, which has been externally validated in several independent cohorts. Despite some limitations, the strengths make the Dutch FRAX tool a good candidate for implementation into clinical practice. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00198-011-1852-2Authors A. Lalmohamed, Division of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The NetherlandsP. M. J. Welsing, Department of Rheumatology & Clinical Immunology, Univer... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5460230 Sat, 26 Nov 2011 06:40:11 +0100 5460230 http://www.medworm.com/index.php?rid=5460232&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F1m21300113n44j84%2F We describe for the first time a case of de novo AIH associated with the administration of parathyroid hormone 1–34 [PTH(1–34)] and PTH(1–84) for severe osteoporosis. A 61-year-old woman was referred to our metabolic bone clinic due to severe osteoporosis, 3 years after LT for primary biliary cirrhosis. Initial treatment with PTH(1–34) led to asymptomatic hypertransaminasemia (two-fold the upper limit of normal), which normalized after drug discontinuation. A new flare of transaminases (three-fold the upper limit of normal) along with elevated alkaline phosphatase was observed after administration of PTH(1–84), which did not resolve after PTH(1–84) withdrawal. Subsequently, after exclusion of common causes of liver enzyme elevation, a liver biopsy was performed. Hist... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5460232 Sat, 26 Nov 2011 06:40:10 +0100 5460232 http://www.medworm.com/index.php?rid=5450748&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw088x73310xj205x%2F Conclusion  Cohort studies that have evaluated the performance of FRAX need to be interpreted with caution and preferably re-evaluated. Content Type Journal ArticleCategory Opinion PaperPages 1-9DOI 10.1007/s00198-011-1846-0Authors J. A. Kanis, WHO Collaborating Centre for Metabolic Bone Diseases, University of Sheffield Medical School, Beech Hill Road, Sheffield, S10 2RX UKA. Oden, WHO Collaborating Centre for Metabolic Bone Diseases, University of Sheffield Medical School, Beech Hill Road, Sheffield, S10 2RX UKH. Johansson, WHO Collaborating Centre for Metabolic Bone Diseases, University of Sheffield Medical School, Beech Hill Road, Sheffield, S10 2RX UKE. McCloskey, WHO Collaborating Centre for Metabolic Bone Diseases, University of Sheffield Medical School, Beech Hil... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5450748 Fri, 25 Nov 2011 17:43:12 +0100 5450748 http://www.medworm.com/index.php?rid=5450749&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F126772246x6j8525%2F Content Type Journal ArticleCategory LetterPages 1-1DOI 10.1007/s00198-011-1845-1Authors G. Grimnes, Tromsø Endocrine Research Group, Department of Clinical Medicine, University of Tromsø, 9037 Tromsø, Norway Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5450749 Wed, 23 Nov 2011 17:43:42 +0100 5450749 http://www.medworm.com/index.php?rid=5450750&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp010685nj62v116u%2F Content Type Journal ArticlePages 1-2DOI 10.1007/s00198-011-1844-2Authors R. P. Heaney, Creighton University, Omaha, NE, USA Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5450750 Wed, 23 Nov 2011 17:43:41 +0100 5450750 http://www.medworm.com/index.php?rid=5450751&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F60pm8v412r440076%2F Conclusions  These results suggest that the anatomical distribution of VF differs between children and adults, perhaps relating to the different shape of the immature spine, notably the changing ratio of kyphosis to lordosis. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s00198-011-1837-1Authors K. Siminoski, Department of Radiology and Diagnostic Imaging, University of Alberta, 6628-123 Street, Edmonton, AB, Canada T6H 3T6K.-C. Lee, Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, CanadaH. Jen, Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, CanadaR. Warshawski, Department of Radiology and Diagnostic Imaging, University of Alberta, Edmonton, CanadaM. A. Matzinger, Department... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5450751 Wed, 23 Nov 2011 16:40:37 +0100 5450751 http://www.medworm.com/index.php?rid=5450752&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fjh485671373467gh%2F Conclusions  The incidence of vertebral fracture in South Korea was comparable with other countries such as Switzerland, and the mortality after vertebral fracture is higher than that of normal populations. The incidence of osteoporotic vertebral fracture and following high mortality are likely to become serious socioeconomic problems. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00198-011-1833-5Authors Y.-K. Lee, Department of Orthopaedic Surgery, Seoul National University Bundang Hospital, Yeongeon-dong, Jongno-gu, Seoul, 110-744 South KoreaS. Jang, Inje University College of Pharmacy, 607 Eobang-dong, Gimhae-si, Gyeongsangnam-do, South KoreaS. Jang, Graduate School of Public Health, Seoul National University, 1 Gwanak-ro, Gwanak-gu, S... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5450752 Tue, 22 Nov 2011 18:01:27 +0100 5450752 http://www.medworm.com/index.php?rid=5450753&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq22123877612255t%2F Conclusion  Our data suggest that plasma FGF23 is an independent biomarker of vascular calcification in patients with various CKD stages including early stages. The association between vascular calcification and FGF23 levels appears to be independent of BMD. It remains to be seen whether this association is independent of bone turnover and bone mass. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00198-011-1838-0Authors L. Desjardins, INSERM ERI-12 (EA 4292), UFR de Médecine et Pharmacie, Jules Verne University of Picardy, Amiens, FranceS. Liabeuf, INSERM ERI-12 (EA 4292), UFR de Médecine et Pharmacie, Jules Verne University of Picardy, Amiens, FranceC. Renard, Division of Radiology, Amiens University Medical Center, Amiens, FranceA. Len... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5450753 Tue, 22 Nov 2011 18:01:26 +0100 5450753 http://www.medworm.com/index.php?rid=5424174&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F7247556400667500%2F Conclusions  Our results suggest that the genetic polymorphisms in both human ALOX12 and ALOX15 may contribute to variations in the peak BMD of Chinese women. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00198-011-1835-3Authors W.-J. Xiao, Metabolic Bone Disease and Genetics Research Unit, Department of Osteoporosis and Bone Diseases, Shanghai Sixth People’s Hospital, Shanghai Jiaotong University, Shanghai, 200233 ChinaY.-H. Ke, Metabolic Bone Disease and Genetics Research Unit, Department of Osteoporosis and Bone Diseases, Shanghai Sixth People’s Hospital, Shanghai Jiaotong University, Shanghai, 200233 ChinaJ.-W. He, Metabolic Bone Disease and Genetics Research Unit, Department of Osteoporosis and Bone Diseases, Shanghai Sixth People�... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5424174 Wed, 16 Nov 2011 18:02:05 +0100 5424174 http://www.medworm.com/index.php?rid=5424176&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F8u0x57654622206h%2F Conclusions  The data suggest that there may be regional differences in the proportion of major fractures that are hip fractures in postmenopausal women. In contrast, the regional and age-related variations in the proportion of fractures that are major fractures appear to be modest. However, because of the limited number of fractures in our sample, further studies are necessary to confirm these findings. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s00198-011-1840-6Authors J. Pfeilschifter, Department of Internal Medicine III, Alfried Krupp Krankenhaus, Essen, GermanyC. Cooper, MRC Lifecourse Epidemiology Unit, Southampton General Hospital, University of Southampton, Southampton, UKN. B. Watts, Bone Health and Osteoporosis Center, Unive... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5424176 Wed, 16 Nov 2011 06:48:56 +0100 5424176 http://www.medworm.com/index.php?rid=5424175&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq16133375720154p%2F Conclusions  Microarchitectural measures of individual trabeculae that contribute to bone strength have been identified. In addition to the contribution of BV/TV, trabecular rod morphology increased the determination of AP strength by 57%, whereas measures of trabecular plate and rod morphology increased determination of SI strength by 13%. Decomposing vertebral body bone architecture into its constituent morphological elements shows that trabecular element morphology has specific functional roles to assist in maintaining skeletal integrity. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00198-011-1832-6Authors I. H. Parkinson, Bone and Joint Research Laboratory, SA Pathology and Hanson Institute, Frome Road, Adelaide, South Australia 50... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5424175 Wed, 16 Nov 2011 06:48:56 +0100 5424175 http://www.medworm.com/index.php?rid=5424178&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fqt5x18788lhmn767%2F Content Type Journal ArticleCategory LetterPages 1-3DOI 10.1007/s00198-011-1830-8Authors B. Jönsson, Stockholm School of Economics, Box 6501, 11383 Stockholm, SE, SwedenO. Ström, Geriatrics and Medicine, McMaster University, Main St W, 1280 Hamilton, ON, CanadaJ. A. Eisman, Geriatrics and Medicine, McMaster University, Main St W, 1280 Hamilton, ON, CanadaA. Papaioannou, Geriatrics and Medicine, McMaster University, Main St W, 1280 Hamilton, ON, CanadaE. S. Siris, Geriatrics and Medicine, McMaster University, Main St W, 1280 Hamilton, ON, CanadaA. Tosteson, Geriatrics and Medicine, McMaster University, Main St W, 1280 Hamilton, ON, CanadaJ. A. Kanis, Geriatrics and Medicine, McMaster University, Main St W, 1280 Hamilton, ON, Canada Journal Osteoporosis InternationalOnline ISSN ... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5424178 Tue, 15 Nov 2011 17:00:49 +0100 5424178 http://www.medworm.com/index.php?rid=5424177&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F917gn76r20547k30%2F Conclusions  There were no significant differences in quality of life between patients receiving zoledronic acid or alendronate. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00198-011-1834-4Authors P. Hadji, Philipps University, Marburg, GermanyV. Ziller, Philipps University, Marburg, GermanyD. Gamerdinger, Orthopedic Practice, Bautzen, GermanyW. Spieler, Research Center for Osteology and Rheumatology, Zerbst, GermanyK. Articus, Novartis Pharma GmbH, Nuremberg, GermanyM. Baier, Novartis Pharma GmbH, Nuremberg, GermanyR. Moericke, Endocrinologic Practice, Magdeburg, GermanyP. H. Kann, Philipps University, Marburg, Germany Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5424177 Tue, 15 Nov 2011 17:00:49 +0100 5424177 http://www.medworm.com/index.php?rid=5411326&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F179n6x238485363x%2F Content Type Journal ArticleCategory ErratumPages 1-1DOI 10.1007/s00198-011-1841-5Authors C. W. Rhee, Department of Preventive Medicine, Seoul National University College of Medicine, 103 Daehangno, Jongno-Gu, Seoul, 110-799 South KoreaJ. Lee, Medical Research Collaborating Center, Seoul National University Hospital, Seoul, South KoreaS. Oh, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South KoreaN. K. Choi, Department of Preventive Medicine, Seoul National University College of Medicine, 103 Daehangno, Jongno-Gu, Seoul, 110-799 South KoreaB. J. Park, Department of Preventive Medicine, Seoul National University College of Medicine, 103 Daehangno, Jongno-Gu, Seoul, 110-799 South Korea Journal Osteoporosis InternationalOnline ISSN 1433-296... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5411326 Mon, 14 Nov 2011 16:58:50 +0100 5411326 http://www.medworm.com/index.php?rid=5411327&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq4303526713q2580%2F Abstract  The diagnosis of osteoporosis rests on areal bone mineral density (BMD) measurement using DXA. Cancellous bone microarchitecture is a key determinant of bone strength but cannot be measured using DXA. To meet the need for a clinical tool capable of assessing bone microarchitecture, the TBS was developed. The TBS is a texture parameter that evaluates pixel gray-level variations in DXA images of the lumbar spine. The TBS variations may reflect bone microarchitecture. We explain the general principles used to compute the TBS, and we report the correlations between TBS and microarchitectural parameters. Several limitations of the TBS as it is used now are pointed out. We discuss data from currently available clinical studies on the ability of the TBS to identify patie... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5411327 Mon, 14 Nov 2011 16:58:49 +0100 5411327 http://www.medworm.com/index.php?rid=5411328&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv6r2g2812232v558%2F Conclusion  Use of ACE inhibitors but not ARB may marginally increase bone loss in older men. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00198-011-1831-7Authors T. Kwok, Department of Medicine & Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, Hong KongJ. Leung, Jockey Club Centre for Osteoporosis Care and Control, The Chinese University of Hong Kong, Hong Kong, Hong KongY. F. Zhang, The Affiliated Hospital of Nantong University, Nantong, ChinaD. Bauer, UCSF, San Francisco, CA, USAK. E. Ensrud, VA Medical Center, Medicine, Boston, USAE. Barrett-Connor, Family & Preventive Medicine, UCSD, San Diego, CA, USAP. C. Leung, Jockey Club Centre for Osteoporosis Care and Control, The Chinese University of Hong... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5411328 Sat, 12 Nov 2011 06:47:11 +0100 5411328 http://www.medworm.com/index.php?rid=5411329&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw1177h311w5t31j2%2F Conclusions  In contrast to 25(OH)D2, 25(OH)D3 was positively related to subsequent cortical bone mass and predicted strength. In vitamin D-deficient children in whom supplementation is being considered, our results suggest that D3 should be used in preference to D2. Content Type Journal ArticleCategory Original ArticlePages 1-12DOI 10.1007/s00198-011-1813-9Authors A. Sayers, Musculoskeletal Research Unit, School of Clinical Sciences, University of Bristol, Bristol, UKW. D. Fraser, Norwich Medical School, Faculty of Medicine and Health Sciences, University of East Anglia, Norwich, UKD. A. Lawlor, MRC Centre for Causal Analyses in Translational Epidemiology, School of Social and Community Medicine, University of Bristol, Bristol, UKJ. H. Tobias, Musculoskeletal Researc... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5411329 Fri, 11 Nov 2011 16:43:46 +0100 5411329 http://www.medworm.com/index.php?rid=5411330&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fau51r3nxq71tu660%2F Conclusion  Size-corrected WB BMC of GHD children were comparable with controls, and bones were normally adapted for muscle mass. Determinants of bone strength which may primarily be affected by GHD are muscle mass, bone size, and geometry rather than bone mass. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00198-011-1825-5Authors M. Gahlot, Department of Dietetics and Nutrition, All India Institute of Medical Sciences, New Delhi, IndiaR. Khadgawat, Department of Endocrinology and Metabolism, All India Institute of Medical Sciences, New Delhi, IndiaR. Ramot, Department of Endocrinology and Metabolism, All India Institute of Medical Sciences, New Delhi, IndiaM. Eunice, Department of Endocrinology and Metabolism, All India Institute of Medic... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5411330 Wed, 09 Nov 2011 17:45:42 +0100 5411330 http://www.medworm.com/index.php?rid=5411332&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fjkr9u6645671h6vn%2F Conclusions  In T1D, UC-OC appears to correlate positively with markers of insulin exposure, either endogenously produced or exogenously administered. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00198-011-1807-7Authors K. M. Thrailkill, Department of Pediatrics, University of Arkansas for Medical Sciences and Arkansas Children’s Hospital Research Institute, Little Rock, AR 72205, USAC.-H. Jo, Department of Pediatrics, University of Arkansas for Medical Sciences and Arkansas Children’s Hospital Research Institute, Little Rock, AR 72205, USAG. E. Cockrell, Department of Pediatrics, University of Arkansas for Medical Sciences and Arkansas Children’s Hospital Research Institute, Little Rock, AR 72205, USAC. S. Moreau, Department of Ped... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5411332 Wed, 09 Nov 2011 06:59:56 +0100 5411332 http://www.medworm.com/index.php?rid=5411331&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ftvj2w70324323769%2F Conclusions  We found that elderly women who sustained a hip fracture had increased mortality risk. The excess mortality was highest short time after the fracture, but persisted for several years after the fracture, and was not explained by pre-fracture medical conditions. Content Type Journal ArticleCategory Original ArticlePages 1-5DOI 10.1007/s00198-011-1811-yAuthors A. B. Grønskag, Department of Public Health and General Practice, Norwegian University of Science and Technology, PB 8905, 7491 Trondheim, NorwayP. Romundstad, Department of Public Health and General Practice, Norwegian University of Science and Technology, PB 8905, 7491 Trondheim, NorwayS. Forsmo, Department of Public Health and General Practice, Norwegian University of Science and Technology, PB 89... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5411331 Wed, 09 Nov 2011 06:59:56 +0100 5411331 http://www.medworm.com/index.php?rid=5411333&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F98t33557725056k8%2F Content Type Journal ArticleCategory LetterPages 1-2DOI 10.1007/s00198-011-1826-4Authors D. H. Solomon, Division of Rheumatology, Brigham and Women’s Hospital, Boston, MA, USAK. Saag, Centers for Education and Research on Therapeutics, University of Alabama at Birmingham, Birmingham, AL, USAM. M. Safford, Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, AL, USA Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5411333 Wed, 09 Nov 2011 06:59:55 +0100 5411333 http://www.medworm.com/index.php?rid=5411334&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F76x620626q5438j7%2F Conclusions  Patients are prepared to accept higher absolute fracture risk than doctors, before considering pharmacological therapy to be justified. Patients require that drug treatments confer substantial fracture risk reductions in order to consider long-term therapy. Content Type Journal ArticleCategory Original ArticlePages 1-6DOI 10.1007/s00198-011-1823-7Authors F. Douglas, Department of Medicine, University of Auckland, Private Bag 92019, Auckland, 1142 New ZealandK. J. Petrie, Department of Psychological Medicine, University of Auckland, Private Bag 92019, Auckland, 1142 New ZealandT. Cundy, Department of Medicine, University of Auckland, Private Bag 92019, Auckland, 1142 New ZealandA. Horne, Department of Medicine, University of Auckland, Private Bag 92019, A... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5411334 Mon, 07 Nov 2011 17:13:29 +0100 5411334 http://www.medworm.com/index.php?rid=5390693&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fqtg8r387572w33w1%2F Conclusions  In this cohort of young and old men and women from Rochester, MN, USA who are matched by FN aBMD, because of the offsetting effects of bone size and vBMD, femoral strength and the load-to-strength ratio tended to be relatively similar across the sexes. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00198-011-1822-8Authors B. Srinivasan, Endocrine Research Unit, Mayo Clinic, Guggenheim 7, 200 First Street SW, Rochester, MN 55905, USAD. L. Kopperdahl, O. N. Diagnostics, Berkeley, CA, USAS. Amin, Division of Rheumatology, Mayo Clinic, Rochester, MN, USAE. J. Atkinson, Department of Health Sciences Research, Mayo Clinic, Rochester, MN, USAJ. Camp, Biomedical Imaging Resource, College of Medicine, Mayo Clinic, Rochester, MN, USAR. ... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5390693 Sat, 05 Nov 2011 15:44:36 +0100 5390693 http://www.medworm.com/index.php?rid=5390695&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv42344582tm5115g%2F Conclusions  The present study provides evidence of the significant association between ROR2 variants and the OPG/RANKL ratio in human plasma and also suggests ROR2 association with HOA. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00198-011-1820-xAuthors S. Ermakov, Human Population Biology Research Unit, Department of Anatomy and Anthropology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, IsraelS. Trofimov, Human Population Biology Research Unit, Department of Anatomy and Anthropology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, IsraelI. Malkin, Human Population Biology Research Unit, Department of Anatomy and Anthropology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, IsraelG. Livshits, Human ... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5390695 Fri, 04 Nov 2011 16:51:01 +0100 5390695 http://www.medworm.com/index.php?rid=5390694&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fdvx030w8240xm527%2F Conclusions  The iGCTLS had a high prevalence of low BMD. We found that male sex, low LM, and delayed start of adult GH replacement were risk factors for osteoporosis. Therefore, the BMD of all iGCTLS should be evaluated, and if it is low, proper management should be started early. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00198-011-1821-9Authors M. J. Kang, Department of Pediatrics, Seoul National University College of Medicine, Seoul, 110-744 South KoreaS. M. Kim, Department of Pediatrics, Seoul National University College of Medicine, Seoul, 110-744 South KoreaY. A. Lee, Department of Pediatrics, Seoul National University College of Medicine, Seoul, 110-744 South KoreaC. H. Shin, Department of Pediatrics, Seoul National University ... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5390694 Fri, 04 Nov 2011 16:51:01 +0100 5390694 http://www.medworm.com/index.php?rid=5366697&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe83714466k7u0366%2F Conclusions  Significantly decreased serum sclerostin was evidenced in PHPT patients as compared with PTX and euparathyroid controls. The inverse PTH and sclerostin relationship suggests that sclerostin is downregulated by PTH in humans. Serum sclerostin normalized earlier than BTMs following parathyroidectomy. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00198-011-1806-8Authors M.-S. M. Ardawi, Center of Excellence for Osteoporosis Research, and Faculty of Medicine, King Abdulaziz University, P.O. Box No. 20724, Jeddah, 21465 Saudi ArabiaA. M. Al-Sibiany, Center of Excellence for Osteoporosis Research, and Faculty of Medicine, King Abdulaziz University, P.O. Box No. 20724, Jeddah, 21465 Saudi ArabiaT. M. Bakhsh, Center of Excellence for... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5366697 Mon, 31 Oct 2011 16:51:15 +0100 5366697 http://www.medworm.com/index.php?rid=5366698&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2k467463w04k456w%2F Conclusions  The fracture healing in KO mice was enhanced in the early stage of neovascularization and the middle stage of endochondral ossification, but not by the end of healing. Blockade of ERbeta can be considered as another therapeutic strategy for osteoporotic fracture and non-union fracture. Content Type Journal ArticleCategory Original ArticlePages 1-13DOI 10.1007/s00198-011-1812-xAuthors Y.-X. He, Musculoskeletal Research Laboratory, Department of Orthopedics and Traumatology, The Chinese University of Hong Kong, Shatin, Hong Kong, ChinaZ. Liu, Musculoskeletal Research Laboratory, Department of Orthopedics and Traumatology, The Chinese University of Hong Kong, Shatin, Hong Kong, ChinaX.-H. Pan, Musculoskeletal Research Laboratory, Department of Orthopedics a... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5366698 Fri, 28 Oct 2011 17:11:33 +0100 5366698 http://www.medworm.com/index.php?rid=5366701&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F16451xl237050195%2F Content Type Journal ArticleCategory ErratumPages 1-1DOI 10.1007/s00198-011-1827-3Authors J. Compston, Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 0QQ UK Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5366701 Fri, 28 Oct 2011 17:11:32 +0100 5366701 http://www.medworm.com/index.php?rid=5366700&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh53u012488888668%2F Conclusions  These data suggest that participation in BBB may not result in direct benefits to bone. However long-term participation may be associated with other positive outcomes. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s00198-011-1816-6Authors A. McNamara, Biological and Population Health Sciences, Oregon State University, Corvallis, OR, USAK. Gunter, Biological and Population Health Sciences, Oregon State University, Corvallis, OR, USA Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5366700 Fri, 28 Oct 2011 17:11:32 +0100 5366700 http://www.medworm.com/index.php?rid=5366699&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr7760kwn1837g152%2F Conclusions  This study confirms that heel QUS, using validated devices, predicts risk of different fracture outcomes in elderly men and women. Further research is needed for more widespread utilisation of the heel QUS in clinical settings across the world. Content Type Journal ArticleCategory Original ArticlePages 1-11DOI 10.1007/s00198-011-1817-5Authors A. Moayyeri, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UKJ. E. Adams, Manchester Royal Infirmary, Central Manchester Universities Hospitals NHS Foundation Trust, Manchester, UKR. A. Adler, Department of Internal Medicine and Department of Epidemiology and Community Health, Virginia Commonwealth University School of Medicine, Richmond, VA, USAM.-A. Krieg, Lausanne University Hos... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5366699 Fri, 28 Oct 2011 17:11:32 +0100 5366699 http://www.medworm.com/index.php?rid=5338710&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F228810653375x55w%2F Conclusions  The choice of BMD input to the FRAX model has a large effect on performance. The lumbar spine T-score or minimum T-score should not be used as inputs to the FRAX algorithm. Use of a weighted mean between the lumbar spine and femoral neck T-scores slightly improves risk classification. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00198-011-1814-8Authors W. D. Leslie, University of Manitoba, Winnipeg, CanadaL. M. Lix, University of Saskatchewan, Saskatoon, CanadaH. Johansson, Gothenburg, SwedenA. Oden, Gothenburg, SwedenE. McCloskey, Osteoporosis Centre, Northern General Hospital, Sheffield, UKJ. A. Kanis, WHO Collaborating Centre for Metabolic Bone Diseases, University of Sheffield, Sheffield, UKfor the Manitoba Bone Density ... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5338710 Wed, 19 Oct 2011 05:55:56 +0100 5338710 http://www.medworm.com/index.php?rid=5338711&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F91g78770585q3611%2F Conclusions  Non-traumatic fractures at any site have serious consequences, including institutionalization. Men are at greater risk of transfer to long-term care following fracture than women. Content Type Journal ArticleCategory Short CommunicationPages 1-6DOI 10.1007/s00198-011-1815-7Authors S. Morin, Division of General Internal Medicine, McGill University Health Center (MUHC), 1650 Cedar Ave, Room B2-118, Montreal, QC H3G 1A4, CanadaL. M. Lix, University of Saskatchewan, Saskatoon, CanadaM. Azimaee, University of Manitoba, Winnipeg, CanadaC. Metge, University of Manitoba, Winnipeg, CanadaS. R. Majumdar, University of Alberta, Edmonton, AB, CanadaW. D. Leslie, University of Manitoba, Winnipeg, Canada Journal Osteoporosis InternationalOnline ISSN 1433-2965Pri... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5338711 Wed, 19 Oct 2011 05:55:55 +0100 5338711 http://www.medworm.com/index.php?rid=5338712&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F10j72410647n2637%2F Conclusions  Low serum 25(OH)D is associated with a substantial excess risk of death compared to 25(OH)D values greater than 50–70 nmol/l, but the association attenuates with time. These findings, if causally related, have important implications for intervention in elderly men. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00198-011-1809-5Authors H. Johansson, Centre for Bone and Arthritis Research (CBAR) at the Sahlgrenska Academy, Institute of Medicine, University of Gothenburg, Gibraltargatan 1 C, 411 32 Gothenburg, SwedenA. Odén, Centre for Bone and Arthritis Research (CBAR) at the Sahlgrenska Academy, Institute of Medicine, University of Gothenburg, Gibraltargatan 1 C, 411 32 Gothenburg, SwedenJ. Kanis, WHO Collaborating Cent... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5338712 Wed, 19 Oct 2011 05:55:54 +0100 5338712 http://www.medworm.com/index.php?rid=5338714&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F311155l71r314g06%2F Conclusion  This study demonstrated that fat mass was inversely related to BMC after removing the mechanical loading effect in Korean men and women. Moreover, abdominal obesity as measured by WC was significantly associated with BMC independent of total fat mass. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00198-011-1808-6Authors J. H. Kim, Department of Internal Medicine, Seoul National University College of Medicine, 28 Yungun-Dong, Chongno-Gu, Seoul, 110-744 South KoreaH. J. Choi, Department of Internal Medicine, Seoul National University College of Medicine, 28 Yungun-Dong, Chongno-Gu, Seoul, 110-744 South KoreaM. J. Kim, Department of Internal Medicine, Seoul National University College of Medicine, 28 Yungun-Dong, Chongno-Gu, Seou... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5338714 Tue, 18 Oct 2011 05:45:38 +0100 5338714 http://www.medworm.com/index.php?rid=5338713&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb7mm7777155r3623%2F Conclusions  The radiomorphometric indices applied in the present study can be used on panoramic radiographs to detect the presence of low bone density in SCD subjects. Content Type Journal ArticleCategory Original ArticlePages 1-6DOI 10.1007/s00198-011-1810-zAuthors F. S. Neves, Department of Oral Diagnosis, Division of Oral Radiology, Piracicaba Dental School, State University of Campinas, Av Limeira, 901, Areião, Piracicaba, São Paulo, Brazil 13414-018L. S. A. F. Oliveira, Department of Oral and Maxillofacial Radiology, School of Dentistry, Federal University of Bahia, Salvador, Bahia, BrazilM. G. G. Torres, Department of Oral and Maxillofacial Radiology, School of Dentistry, Federal University of Bahia, Salvador, Bahia, BrazilM. B. P. Toralles, Department of Ped... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5338713 Tue, 18 Oct 2011 05:45:38 +0100 5338713 http://www.medworm.com/index.php?rid=5325806&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F453243l17v25r634%2F Conclusion  Hemiarthroplasty was a cost-effective treatment. Trial registration, NCT00464230. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00198-011-1772-1Authors G. M. Waaler Bjørnelv, Department of Health Management and Health Economics, University of Oslo, 1089, Blindern, 0317 Oslo, NorwayF. Frihagen, Orthopaedic Department, Oslo University Hospital, Kirkeveien 166, 0407 Oslo, NorwayJ. E. Madsen, Orthopaedic Department, Oslo University Hospital, Kirkeveien 166, 0407 Oslo, NorwayL. Nordsletten, Orthopaedic Department, Oslo University Hospital, Kirkeveien 166, 0407 Oslo, NorwayE. Aas, Department of Health Management and Health Economics, University of Oslo, 1089, Blindern, 0317 Oslo, Norway Journal Osteoporosis InternationalOnline I... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5325806 Fri, 14 Oct 2011 06:08:32 +0100 5325806 http://www.medworm.com/index.php?rid=5325807&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb76841548nu31p44%2F Abstract  In recent years, atypical femoral fractures and osteonecrosis of the jaw have emerged as potential complications of long-term bisphosphonate therapy; osteonecrosis of the jaw has also been reported in patients receiving high doses of denosumab. The pathophysiology of both conditions is poorly defined, and the underlying mechanisms are likely to differ. The initiation of atypical fractures in the lateral femoral shaft suggests that reduced tensile strength, possibly secondary to alterations in the material properties of bone resulting from low bone turnover, may be an important pathogenetic factor. Osteonecrosis of the jaw is characterised by infection, inflammation, bone resorption and bone necrosis, but the sequence in which these occur has not been established. ... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5325807 Thu, 13 Oct 2011 15:50:30 +0100 5325807 http://www.medworm.com/index.php?rid=5317284&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F4254h2u701240407%2F Conclusions  Bone metabolism at the spine remained suppressed following treatment discontinuation. A significant increase in SUV at the femoral shaft and total hip after 12 months was observed but for the ALN group only. This study was small, and further clinical studies are required to fully evaluate the persistence of BP treatment. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s00198-011-1805-9Authors M. L. Frost, Osteoporosis Research Unit, King’s College London, Guy’s Hospital Campus, Great Maze Pond, London, SE1 9RT UKM. Siddique, Osteoporosis Research Unit, King’s College London, Guy’s Hospital Campus, Great Maze Pond, London, SE1 9RT UKG. M. Blake, Osteoporosis Research Unit, King’s College London, Guy’s Hospital C... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5317284 Sat, 08 Oct 2011 05:51:51 +0100 5317284 http://www.medworm.com/index.php?rid=5306499&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj51178264g361881%2F Conclusions  With regard to increased risk of VFs in postmenopausal Korean women with type 2 diabetes mellitus, radiographic vertebral assessment would be useful for the clinical identification of osteoporosis and fractures. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00198-011-1803-yAuthors Y. J. Choi, Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, South KoreaS.-O. Yang, Department of Radiology and Radiologic Science, Asia Cancer Center, Busan, South KoreaC. S. Shin, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, South KoreaY.-S. Chung, Department of Endocrinology and Metabolism, Ajou University School of Medicine, Suwon, South Korea Journal Osteoporo... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5306499 Thu, 06 Oct 2011 06:28:47 +0100 5306499 http://www.medworm.com/index.php?rid=5306500&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F20288424351u3042%2F Conclusions  This post hoc analysis suggests that zoledronic acid is significantly more effective than risedronate in increasing LS BMD in prevention and treatment of glucocorticoid-induced osteoporosis across a wide range of patients Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00198-011-1800-1Authors C. Roux, Rheumatology Department, Paris Descartes University, Hopital Cochin, 27 rue du Faubourg Saint Jacques, 75679 Paris cedex 14, FranceD. M. Reid, University of Aberdeen, Aberdeen, UKJ.-P. Devogelaer, Universite Catholique de Louvain, Brussels, BelgiumK. Saag, University of Alabama at Birmingham, Birmingham, AL, USAC. S. Lau, University of Hong Kong, Hong Kong, People’s Republic of ChinaJ.-Y. Reginster, University of Liege, Liege, Be... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5306500 Thu, 06 Oct 2011 06:28:46 +0100 5306500 http://www.medworm.com/index.php?rid=5306501&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr2085311r8075234%2F Conclusions  Treatment with IV ibandronate 2 mg bimonthly or 3 mg quarterly is effective and well tolerated for up to 5 years in women with postmenopausal osteoporosis. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s00198-011-1793-9Authors G. Bianchi, Division of Rheumatology, Azienda Sanitaria Genovese, Genoa, ItalyE. Czerwinski, Krakow Medical Centre, Krakow, PolandA. Kenwright, Roche Products Limited, Welwyn Garden City, UKA. Burdeska, F. Hoffmann-La Roche Ltd., Basel, SwitzerlandR. R. Recker, Osteoporosis Research Center, Creighton University, Omaha, NE, USAD. Felsenberg, Charité—Campus Benjamin Franklin, Freie and Humboldt-Universität Berlin, Berlin, Germany Journal Osteoporosis InternationalOnline ISSN 1433-... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5306501 Thu, 06 Oct 2011 06:28:45 +0100 5306501 http://www.medworm.com/index.php?rid=5276401&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fgt14m374653p70n4%2F Conclusion  Based on the meta-analysis, brief high-impact exercise improves BMD at the hip but not at the lumbar spine. Effectiveness of this form of exercise as a lifestyle physical activity for prevention of osteoporosis should be explored in larger populations. Content Type Journal ArticleCategory Original ArticlePages 1-11DOI 10.1007/s00198-011-1801-0Authors O. O. Babatunde, Centre for Sport, Health and Exercise Research, Staffordshire University, Leek Road, Stoke on Trent, ST4 2DF UKJ. J. Forsyth, Centre for Sport, Health and Exercise Research, Staffordshire University, Leek Road, Stoke on Trent, ST4 2DF UKC. J. Gidlow, Centre for Sport, Health and Exercise Research, Staffordshire University, Leek Road, Stoke on Trent, ST4 2DF UK Journal Osteoporosis Inter... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5276401 Wed, 28 Sep 2011 05:49:05 +0100 5276401 http://www.medworm.com/index.php?rid=5276400&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq20h7jl5454ll7t2%2F Conclusions  There were no tolerability concerns or new safety signals. Monthly treatment with ibandronate 100 and 150 mg is effective and well tolerated for up to 5 years in women with postmenopausal osteoporosis. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s00198-011-1773-0Authors P. D. Miller, Colorado Center for Bone Research, Lakewood, CO, USAR. R. Recker, Osteoporosis Research Center, Omaha, NE, USAJ.-Y. Reginster, University of Liège, Liège, BelgiumB. J. Riis, Center for Clinical and Basic Research, Ballerup, DenmarkE. Czerwinski, Krakow Medical Centre, Krakow, PolandD. Masanauskaite, F. Hoffmann-La Roche Ltd., Basel, SwitzerlandA. Kenwright, Roche Products Limited, Welwyn Garden City, UKR. Lorenc, The Children’s Mem... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5276400 Wed, 28 Sep 2011 05:49:05 +0100 5276400 http://www.medworm.com/index.php?rid=5276404&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx32632x65627481m%2F Content Type Journal ArticleCategory LetterPages 1-3DOI 10.1007/s00198-011-1799-3Authors B. E. C. Nordin, Endocrine and Metabolic Unit, Royal Adelaide Hospital, North Terrace, Adelaide, SA 5000, AustraliaJ. R. Lewis, Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, WA 6009, AustraliaR. M. Daly, Exercise and Ageing, School of Exercise and Nutrition Sciences, Deakin University, 221 Burwood Highway, Burwood, VIC 3125, AustraliaR. Prince, School of Medicine and Pharmacology, University of Western Australia, 35 Stirling Highway, Crawley, WA 6009, Australia Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5276404 Wed, 28 Sep 2011 05:49:03 +0100 5276404 http://www.medworm.com/index.php?rid=5276403&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F7335567707750778%2F Conclusions  The impact of generic bisphosphonates requires formal testing to re-evaluate their role in the management of osteoporosis. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00198-011-1796-6Authors J. A. Kanis, WHO Collaborating Centre for Metabolic Bone Diseases, University of Sheffield, UK University of Sheffield Medical School, Beech Hill Road, Sheffield, S10 2RX UKJ.-Y. Reginster, Department of Public Health, Epidemiology and Health Economics, University of Liège, Liège, BelgiumJ.-M. Kaufman, Department of Endocrinology and Unit for Osteoporosis and Metabolic Bone Diseases, Ghent University Hospital, Ghent, BelgiumJ.-D. Ringe, Medizin. Klinik 4 (Department Rheumatology/Osteology) and Western German Osteoporosis Center (WOC) at K... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5276403 Wed, 28 Sep 2011 05:49:03 +0100 5276403 http://www.medworm.com/index.php?rid=5276402&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp081u45q26436323%2F Conclusions  The MTFL service is a cost-effective intervention to reduce recurrent osteoporotic fractures. Content Type Journal ArticleCategory Original ArticlePages 1-11DOI 10.1007/s00198-011-1802-zAuthors M. S. Cooper, University of Birmingham, Birmingham, UKA. J. Palmer, Menzies Research Institute Tasmania, University of Tasmania, Medical Science 1 Building, 17 Liverpool St. (Private Bag 23), Hobart, TAS 7000, AustraliaM. J. Seibel, Bone Research Program, ANZAC Research Institute and Department of Endocrinology and Metabolism, Concord Repatriation General Hospital, University of Sydney, Sydney, Australia Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5276402 Wed, 28 Sep 2011 05:49:03 +0100 5276402 http://www.medworm.com/index.php?rid=5276405&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp9536k5445j345r2%2F Conclusions  Risedronate 35 mg DR weekly is similar in efficacy and safety to risedronate 5 mg IR daily, and will allow patients to take their weekly risedronate dose immediately after breakfast. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s00198-011-1791-yAuthors M. R. McClung, Oregon Osteoporosis Center, 5050 NE Hoyt, Suite 626, Portland, OR 97213, USAP. D. Miller, Colorado Center for Bone Research, Lakewood, CO, USAJ. P. Brown, Groupe de recherche en rhumatologie et maladies osseuses, Québec, QC, CanadaJ. Zanchetta, University of El Salvador, Metabolic Research Institute, Buenos Aires, ArgentinaM. A. Bolognese, Bethesda Health Research, Bethesda, MD, USAC. L. Benhamou, Institut de Prévention et de Recherche sur l’Ostéop... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5276405 Tue, 27 Sep 2011 05:48:42 +0100 5276405 http://www.medworm.com/index.php?rid=5252412&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F85264245px2212g2%2F Conclusions  Starting from these differences in the structural descriptors, our study sustains the presence of a compensatory mechanism in osteoarthritis to preserve the mechanical competence of bone structure, despite the loss of trabecular bone, underlying lower fracture risk. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00198-011-1795-7Authors A. Rubinacci, Bone Metabolism Unit, Scientific Institute San Raffaele, via Olgettina 60, 20132 Milan, ItalyD. Tresoldi, IBFM-CNR, via Fratelli Cervi 93, 20090 Segrate, Milan, ItalyE. Scalco, IBFM-CNR, via Fratelli Cervi 93, 20090 Segrate, Milan, ItalyI. Villa, Bone Metabolism Unit, Scientific Institute San Raffaele, via Olgettina 60, 20132 Milan, ItalyF. Adorni, ITB-CNR, via Fratelli Cervi 93, 2... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5252412 Fri, 23 Sep 2011 15:46:53 +0100 5252412 http://www.medworm.com/index.php?rid=5252413&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm7031g077740004w%2F Conclusions  QUS identifies fractured pediatric patients with bone disorders, reflecting the severity of the causative trauma with a high discrimination power for fragility fractures. Content Type Journal ArticleCategory Original ArticlePages 1-12DOI 10.1007/s00198-011-1794-8Authors A. Mussa, Division Pediatric Endocrinology, Department of Pediatrics, University of Turin, Turin, ItalyF. Porta, Division Pediatric Endocrinology, Department of Pediatrics, University of Turin, Turin, ItalyG. Baldassarre, Division Pediatric Endocrinology, Department of Pediatrics, University of Turin, Turin, ItalyG. Tuli, Division Pediatric Endocrinology, Department of Pediatrics, University of Turin, Turin, ItalyF. de Terlizzi, Scientific Department IGEA s.p.a., Biophysics Laboratory, Car... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5252413 Fri, 23 Sep 2011 05:43:45 +0100 5252413 http://www.medworm.com/index.php?rid=5252414&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy57m4p365x2684rh%2F Conclusions  All forms of OC were highly heritable and genetically correlated with total body BMC in these African ancestry families. The identified linkage region contains several candidate genes for bone and energy metabolism including COL1A1 and TNFRSF11A. Further studies of this genomic region may reveal novel insight into the genetic regulation of OC and bone mineralization. Content Type Journal ArticleCategory Original ArticlePages 1-11DOI 10.1007/s00198-011-1763-2Authors A. L. Kuipers, Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 130 DeSoto Street, Pittsburgh, PA 15261, USAC. Gundberg, Department of Orthopaedics and Rehabilitation, Yale School of Medicine, 800 Howard Avenue, New Haven, CT 06510, USAC. M. Kammerer, Depa... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5252414 Wed, 21 Sep 2011 05:55:32 +0100 5252414 http://www.medworm.com/index.php?rid=5252415&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F6046456l24875035%2F Conclusions  The overall moderate evidence from the RCTs confirmed the significantly short-term and middle-term efficacy of BPs on periprosthetic bone loss after joint arthroplasty. To obtain a better efficacy, the second and the third generation of BPs may be the choice. Content Type Journal ArticleCategory Original ArticlePages 1-12DOI 10.1007/s00198-011-1797-5Authors T. Lin, Department of Orthopaedic Surgery, Second Affiliated Hospital School of Medicine, Zhejiang University, Jiefang Road 88, Hangzhou, 310009 People’s Republic of ChinaS.-G. Yan, Department of Orthopaedic Surgery, Second Affiliated Hospital School of Medicine, Zhejiang University, Jiefang Road 88, Hangzhou, 310009 People’s Republic of ChinaX.-Z. Cai, Department of Orthopaedic Surgery, Second Aff... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5252415 Tue, 20 Sep 2011 05:50:56 +0100 5252415 http://www.medworm.com/index.php?rid=5252416&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F56863762121j8250%2F Conclusion  Minodronate at monthly doses of 30 or 50 mg has similar efficacy to the daily 1 mg dose in terms of BMD and bone turnover markers with similar tolerability. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00198-011-1782-zAuthors R. Okazaki, Third Department of Medicine, Teikyo University Chiba Medical Center, 3426-3 Anesaki, Ichihara, Chiba 299-0111, JapanH. Hagino, Rehabilitation Division, Tottori University Hospital, Yonago, JapanM. Ito, Department of Radiology, Nagasaki University School of Medicine, Nagasaki, JapanT. Sone, Department of Nuclear Medicine, Kawasaki Medical School, Kurashiki, Okayama, JapanT. Nakamura, Department of Orthopedic Surgery, University of Occupational and Environmental Health Japan, Kitakyū... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5252416 Tue, 20 Sep 2011 05:50:55 +0100 5252416 http://www.medworm.com/index.php?rid=5252417&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc6p18833477h2727%2F Conclusions  Numerous factors not classically associated with calcium–phosphorus homeostasis are independently associated with PTH and should be considered in future studies of PTH and chronic disease. Additional research is needed to elucidate mechanisms underlying identified associations with PTH and to explore possible racial differences in phosphorus handling. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s00198-011-1776-xAuthors J. M. Paik, Renal Division, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USAW. R. Farwell, Division of Aging, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA, USAE. N. Taylor, Channing Laboratory, Department of Medicin... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5252417 Tue, 20 Sep 2011 05:50:54 +0100 5252417 http://www.medworm.com/index.php?rid=5240798&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F060400p00u4m233v%2F Conclusion  We concluded that composite strength indices have the potential to explain racial/ethnic differences in hip fracture risk, suggesting that composite strength indices may represent ethnicity-independent measures of bone strength. This contention needs to be verified by further research on the fracture predictive ability of composite strength indices in multi-ethnic longitudinal cohorts. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s00198-011-1723-xAuthors S. Ishii, Geriatric Research, Education and Clinical Center (GRECC), VA Greater Los Angeles Healthcare System, 11301 Wilshire Blvd, Building 220, Room 302, Los Angeles, CA 90073, USAJ. A. Cauley, Department of Epidemiology, Graduate School of Public Health, University of Pit... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5240798 Sat, 17 Sep 2011 05:44:41 +0100 5240798 http://www.medworm.com/index.php?rid=5240799&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F7884771144280887%2F Conclusions  The treatment of hip fractures accounts for a significant proportion of the costs associated with the treatment of peripheral osteoporotic fractures. Interventions to reduce the incidence of fractures, particularly hip fractures, would result in significant cost savings to the health care system and would preserve quality of life in many patients. Content Type Journal ArticleCategory Original ArticlePages 1-12DOI 10.1007/s00198-011-1785-9Authors L. Bessette, Department of Medicine, CHUL Research Centre, Laval University, 2705, Laurier boulevard, Room S-763, Quebec City, QC GIV 4G2, CanadaS. Jean, Institut national de santé publique du Québec, Quebec City, QC, CanadaM.-P. Lapointe-Garant, Department of Medicine, CHUL Research Centre, Laval University, 2... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5240799 Sat, 17 Sep 2011 05:44:39 +0100 5240799 http://www.medworm.com/index.php?rid=5240800&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe7725622364m4x56%2F Abstract  Alcohol is widely consumed across the world. It is consumed in both social and cultural settings. Until recently, two types of alcohol consumption were recognized: heavy chronic alcohol consumption or light consumption. Today, there is a new pattern of consumption among teenagers and young adults namely: binge drinking. Heavy alcohol consumption is detrimental to many organs and tissues, including bones, and is known to induce secondary osteoporosis. Some studies, however, have reported benefits from light alcohol consumption on bone parameters. To date, little is known regarding the effects of binge drinking on bone health. Here, we review the effects of three different means of alcohol consumption: light, heavy, and binge drinking. We also review the detailed li... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5240800 Sat, 17 Sep 2011 05:44:38 +0100 5240800 http://www.medworm.com/index.php?rid=5240803&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm16331073l857434%2F Conclusion  This study confirms that dietary collagen reduces bone loss in OVX mice by increasing the diameter of the cortical areas of femurs and can have a preventive effect. Content Type Journal ArticleCategory Original ArticlePages 1-11DOI 10.1007/s00198-011-1788-6Authors F. Guillerminet, AgroParisTech, UMR914 Nutrition Physiology and Ingestive Behavior, 16 rue Claude Bernard, 75005 Paris, FranceV. Fabien-Soulé, Rousselot SAS, 6 rue Jean Jaurès, 92807 Puteaux cedex, FranceP. C. Even, AgroParisTech, UMR914 Nutrition Physiology and Ingestive Behavior, 16 rue Claude Bernard, 75005 Paris, FranceD. Tomé, AgroParisTech, UMR914 Nutrition Physiology and Ingestive Behavior, 16 rue Claude Bernard, 75005 Paris, FranceC.-L. Benhamou, Inserm U658, Orléans Regional Hospital... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5240803 Sat, 17 Sep 2011 05:44:37 +0100 5240803 http://www.medworm.com/index.php?rid=5240802&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw020724342122452%2F Conclusion  Based on the final results of this crossover study after women had received each treatment for up to 1 year, postmenopausal women with osteoporosis were more adherent, compliant, and persistent with subcutaneous denosumab injections every 6 months than with once-weekly alendronate tablets and reported increased treatment preference and satisfaction with injectable denosumab over oral alendronate. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s00198-011-1780-1Authors N. Freemantle, University of Birmingham, Birmingham, UKS. Satram-Hoang, Amgen Inc., Thousand Oaks, CA, USAE.-T. Tang, Amgen Inc., Thousand Oaks, CA, USAP. Kaur, Amgen Inc., Thousand Oaks, CA, USAD. Macarios, Amgen Inc., Thousand Oaks, CA, USAS. Siddhanti... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5240802 Sat, 17 Sep 2011 05:44:37 +0100 5240802 http://www.medworm.com/index.php?rid=5240801&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F67h556n116543q6w%2F Conclusions  Denosumab 60 mg could be an effective dose for Japanese postmenopausal women with osteoporosis as was shown in the Caucasian population. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s00198-011-1786-8Authors T. Nakamura, Department of Orthopedics, University of Occupational and Environmental Health, Kitakyushu, JapanT. Matsumoto, Department of Medicine and Bioregulatory Science, University of Tokushima Graduate School of Health Biosciences, Tokushima, JapanT. Sugimoto, Department of Internal Medicine 1, Shimane University Faculty of Medicine, Shimane, JapanM. Shiraki, Research Institute and Practice for Involutional Diseases, Nagano, Japan Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X ... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5240801 Sat, 17 Sep 2011 05:44:37 +0100 5240801 http://www.medworm.com/index.php?rid=5240804&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F51k02g00212516x4%2F Conclusion  In a group of 113 early, young SpA patients, 15% already had at least one VF. Most VF were asymptomatic, undetected by routine diagnostic procedures and located at the mid-thoracic spine. The VF were associated with low BMD of the lumbar spine and with axial PsA. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00198-011-1766-zAuthors M. A. C. van der Weijden, Department of Rheumatology, VU University Medical Center, Room 3A-64, PO Box 7057, 1007 MB Amsterdam, The NetherlandsI. E. van der Horst-Bruinsma, Department of Rheumatology, VU University Medical Center, Room 3A-64, PO Box 7057, 1007 MB Amsterdam, The NetherlandsJ. C. van Denderen, Department of Rheumatology, Reade, Amsterdam, The NetherlandsB. A. C. Dijkmans, Department o... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5240804 Sat, 17 Sep 2011 05:44:36 +0100 5240804 http://www.medworm.com/index.php?rid=5240805&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc874p24608151817%2F Conclusion  Our gene-based GWAS confirmed several BMD genes and suggested several novel BMD genes. Genetic contribution to BMD variation may operate through multiple genes identified in this study in functional gene networks. This finding may be useful in identifying and prioritizing candidate genes/loci for further study. Content Type Journal ArticleCategory Original ArticlePages 1-12DOI 10.1007/s00198-011-1779-7Authors C.-L. Cheung, Department of Medicine, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, ChinaP.-C. Sham, Department of Psychiatry, The University of Hong Kong, Hong Kong, ChinaS.-M. Xiao, Department of Medicine, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, ChinaC. H. Bow, Department of ... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5240805 Sat, 17 Sep 2011 05:44:33 +0100 5240805 http://www.medworm.com/index.php?rid=5240808&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F3j65766nq0l524w5%2F Conclusion  The semi-automated quantitative vertebral morphometry measurements from CT lateral scout views provided good to excellent agreement with the standard SQ grading for assessment of prevalent vertebral fractures. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s00198-011-1774-zAuthors Y. M. Kim, Center for Advanced Orthopaedic Studies, Beth Israel Deaconess Medical Center, Boston, MA, USAS. Demissie, Department of Biostatistics, Boston University School of Public Health, Boston, MA, USAH. K. Genant, Synarc and University of California San Francisco, San Francisco, CA, USAX. Cheng, Department of Radiology, Peking University, Jishuitan Hospital, Beijing, ChinaW. Yu, Department of Radiology, Peking Union Medical College Hospital, Beiji... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5240808 Sat, 17 Sep 2011 05:44:32 +0100 5240808 http://www.medworm.com/index.php?rid=5240807&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb5gw71nt53324337%2F Conclusion  Increased levels of serum adiponectin were associated with decrease in BMD in male hemodialysis patients. Adiponectin may play a role in mineral and bone disorder, possibly in bone resorption, of patients with CKD 5D. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00198-011-1789-5Authors S. Okuno, Kidney Center, Shirasagi Hospital, 7-11-23, Kumata, Higashisumiyoshi-ku, Osaka, 546-0002 JapanE. Ishimura, Department of Nephrology, Osaka City University Graduate School of Medicine, 1-4-3, Asahi-machi, Abeno-ku, Osaka, 545-8585 JapanK. Norimine, Kidney Center, Shirasagi Hospital, 7-11-23, Kumata, Higashisumiyoshi-ku, Osaka, 546-0002 JapanN. Tsuboniwa, Kidney Center, Shirasagi Hospital, 7-11-23, Kumata, Higashisumiyoshi-ku, Osaka, 546... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5240807 Sat, 17 Sep 2011 05:44:32 +0100 5240807 http://www.medworm.com/index.php?rid=5240806&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu3w2v6x023525604%2F Conclusion  Breastfeeding is beneficial to maternal bone strength in the long run. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00198-011-1790-zAuthors P. K. Wiklund, Department of Health Sciences, University of Jyväskylä, P.O. Box 35 (LL), 40014 Jyväskylä, FinlandL. Xu, Department of Health Sciences, University of Jyväskylä, P.O. Box 35 (LL), 40014 Jyväskylä, FinlandQ. Wang, Endocrine Centre, Austin Health, University of Melbourne, Melbourne, AustraliaT. Mikkola, Department of Health Sciences, University of Jyväskylä, P.O. Box 35 (LL), 40014 Jyväskylä, FinlandA. Lyytikäinen, Department of Health Sciences, University of Jyväskylä, P.O. Box 35 (LL), 40014 Jyväskylä, FinlandE. Völgyi, Health Science Center, Preventive Medicin... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5240806 Sat, 17 Sep 2011 05:44:32 +0100 5240806 http://www.medworm.com/index.php?rid=5212372&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl677m36744373225%2F Conclusion  The incidence of first non-hip femur fractures rose between 1984 and 2007, with an increase in the rates for women after 1995. Content Type Journal ArticleCategory Original ArticlePages 1-6DOI 10.1007/s00198-011-1777-9Authors A. C. Ng, Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Department of Medicine, College of Medicine, Mayo Clinic, Rochester, MN, USAM. T. Drake, Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Department of Medicine, College of Medicine, Mayo Clinic, Rochester, MN, USAB. L. Clarke, Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Department of Medicine, College of Medicine, Mayo Clinic, Rochester, MN, USAS. A. Sems, Department of Orthopedic Surgery, College of Medicine, Mayo Clinic, Roches... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5212372 Sat, 10 Sep 2011 05:47:47 +0100 5212372 http://www.medworm.com/index.php?rid=5212373&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F457242u85071m115%2F Conclusions  Within the constraints of HR-pQCT method, and while a possible artefactual contribution of strontium cannot be quantified, SrRan appeared to influence distal tibia bone microstructure and FEA-determined biomechanical parameters more than alendronate. However, the magnitude of the differences is unclear and requires confirmation with another method. Content Type Journal ArticleCategory Original ArticlePages 1-11DOI 10.1007/s00198-011-1758-zAuthors R. Rizzoli, Division of Bone Diseases, Department of Medical Specialties, Geneva University Hospitals and Faculty of Medicine, 1211 Geneva 14, SwitzerlandR. D. Chapurlat, INSERM U831, Université de Lyon, Edouard Herriot Hospital, Lyon, FranceJ.-M. Laroche, Rangueil Hospital, Toulouse, FranceM. A. Krieg, Departm... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5212373 Sat, 10 Sep 2011 05:47:46 +0100 5212373 http://www.medworm.com/index.php?rid=5212374&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb715682q05487661%2F Conclusions  One year treatment with 6,500 IU vitamin D3/day was not better than 800 IU/day regarding BMD in vitamin D-replete postmenopausal women with reduced bone mass and was less efficient in reducing bone turnover. Content Type Journal ArticleCategory Original ArticlePages 1-11DOI 10.1007/s00198-011-1752-5Authors G. Grimnes, Tromsø Endocrine Research Group, Department of Clinical Medicine, University of Tromsø, 9037 Tromsø, NorwayR. Joakimsen, Tromsø Endocrine Research Group, Department of Clinical Medicine, University of Tromsø, 9037 Tromsø, NorwayY. Figenschau, Department of Medical Biology, University of Tromsø, 9037 Tromsø, NorwayP. A. Torjesen, Hormone Laboratory, Department of Endocrinology, Oslo University Hospital, Aker, 0424 Oslo, Norw... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5212374 Sat, 10 Sep 2011 05:47:45 +0100 5212374 http://www.medworm.com/index.php?rid=5212376&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh013084m0t1223km%2F Content Type Journal ArticleCategory Letter to the EditorPages 1-1DOI 10.1007/s00198-011-1784-xAuthors C. Cure-Cure, Biomelab Research Center, Clinical Research, Barranquilla, ColombiaP. Cure, Office of Innovation Development and Investigational Therapeutics, Children’s National Medical Center, Washington, DC, USA Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5212376 Sat, 10 Sep 2011 05:47:44 +0100 5212376 http://www.medworm.com/index.php?rid=5212375&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj871887777535181%2F Conclusion  The incremental QALYs estimated from the SF-6D were two- to threefold greater than those estimated from the EQ-5D. Given the large magnitude of difference, the choice of preference-based utility instrument may substantially impact health care decisions. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00198-011-1770-3Authors J. C. Davis, Centre for Clinical Epidemiology and Evaluation, VCH Research Institute, The University of British Columbia, Research Pavilion, 7th floor, 828 West 10th Avenue, Vancouver, BC V5Z 1M9, CanadaT. Liu-Ambrose, Department of Physical Therapy, Aging, Mobility, and Cognitive Neuroscience Laboratory, University of British Columbia, 212-2177 Wesbrook Mall, Vancouver, BC, Canada V6T 1Z3K. M. Khan, Centre fo... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5212375 Sat, 10 Sep 2011 05:47:44 +0100 5212375 http://www.medworm.com/index.php?rid=5212378&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fbq70121071875474%2F Conclusions  Rib fracture, the second most common clinical fracture in women (after wrist fracture), predicted future fractures of the rib, wrist, and spine at all ages. Women presenting with rib fractures should be evaluated for appropriate management to prevent future fractures. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00198-011-1757-0Authors S. G. Sajjan, Merck & Co., Inc., West Point, PA, USAE. Barrett-Connor, University of California San Diego, La Jolla, CA, USAC. A. McHorney, Merck & Co., Inc., North Wales, PA, USAP. D. Miller, Colorado Center for Bone Research, Lakewood, CO, USAS. S. Sen, Merck & Co. Inc., Whitehouse Station, NJ, USAE. Siris, Columbia University College of Physicians and Surgeons, New York, NY, USA Jour... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5212378 Fri, 09 Sep 2011 05:47:08 +0100 5212378 http://www.medworm.com/index.php?rid=5212377&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk0u6726p65674v13%2F Conclusions  Use of SSRIs is associated with increased risk of fracture. The SSRIs may exert an increased risk of fracture independent of depression and bone mineral density. Content Type Journal ArticleCategory Original ArticlePages 1-11DOI 10.1007/s00198-011-1778-8Authors Q. Wu, College of Medicine, Mayo Clinic, 13400 E Shea Blvd, Scottsdale, AZ 85259, USAA. F. Bencaz, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA, USAJ. G. Hentz, College of Medicine, Mayo Clinic, 13400 E Shea Blvd, Scottsdale, AZ 85259, USAM. D. Crowell, College of Medicine, Mayo Clinic, 13400 E Shea Blvd, Scottsdale, AZ 85259, USA Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5212377 Fri, 09 Sep 2011 05:47:08 +0100 5212377 http://www.medworm.com/index.php?rid=5212380&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj2322rh0722005r8%2F Conclusion  Treatment of oim/oim mice with either a bisphosphonate or a RANK-Fc causes similar decreases in fracture incidence with increases in metaphyseal bone volume via increased number of thinner trabeculae. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s00198-011-1742-7Authors R. Bargman, NYPH-Weill Cornell Medical Center, New York, NY, USAR. Posham, Hospital for Special Surgery, New York, NY, USAA. L. Boskey, Hospital for Special Surgery, New York, NY, USAE. DiCarlo, Hospital for Special Surgery, New York, NY, USAC. Raggio, Hospital for Special Surgery, New York, NY, USAN. Pleshko, Hospital for Special Surgery, New York, NY, USA Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis ... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5212380 Thu, 08 Sep 2011 05:55:53 +0100 5212380 http://www.medworm.com/index.php?rid=5212379&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ftgk2677380053537%2F Abstract  Fractures are common in patients with chronic kidney disease (CKD) and associated with substantially high morbidity and mortality. Bone mass measurements are commonly used to assess fracture risk in the general population, but the utility of these measurements in patients with CKD, and specifically among those on hemodialysis, is unclear. This review will outline the epidemiology and etiology of fractures in patients with CKD with a particular emphasis on men and women on hemodialysis. As well, we will summarize the published data, which describes the association between risk factors for fracture (including bone mass measurements, biochemical markers of mineral metabolism, and muscle strength) and fractures in patients with CKD. Patients with CKD suffer from fract... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5212379 Thu, 08 Sep 2011 05:55:53 +0100 5212379 http://www.medworm.com/index.php?rid=5212383&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F116801t78l26w152%2F Content Type Journal ArticleCategory Letter to the EditorPages 1-2DOI 10.1007/s00198-011-1783-yAuthors M. J. Bolland, Department of Medicine, University of Auckland, Private Bag 92 019, Auckland, 1142 New ZealandA. Grey, Department of Medicine, University of Auckland, Private Bag 92 019, Auckland, 1142 New ZealandI. R. Reid, Department of Medicine, University of Auckland, Private Bag 92 019, Auckland, 1142 New Zealand Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5212383 Thu, 08 Sep 2011 05:55:51 +0100 5212383 http://www.medworm.com/index.php?rid=5212382&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh767432705851nh4%2F Conclusions  Osteoporosis and aortic calcification appear to be independent processes in a cohort of ambulatory, elderly women. However, potential confounding factors may be present and prospective studies are needed to investigate this situation further. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00198-011-1762-3Authors E. Flipon, INSERM ERI-12 (EA 4292) Jules Verne University of Picardy, Amiens, FranceS. Liabeuf, INSERM ERI-12 (EA 4292) Jules Verne University of Picardy, Amiens, FranceP. Fardellone, INSERM ERI-12 (EA 4292) Jules Verne University of Picardy, Amiens, FranceR. Mentaverri, INSERM ERI-12 (EA 4292) Jules Verne University of Picardy, Amiens, FranceT. Ryckelynck, Jules Verne University of Picardy, Amiens, FranceF. Grados, INS... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5212382 Thu, 08 Sep 2011 05:55:51 +0100 5212382 http://www.medworm.com/index.php?rid=5212381&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Frj0jn00755424156%2F Conclusion  Treatment with 300-mg/day isoflavones (aglycone equivalents) failed to prevent a decline in BMD in the lumbar spine or total femur compared with the placebo group. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s00198-011-1750-7Authors T. Y. Tai, Division of Geriatric Research, Institute of Population Health Sciences, National Health Research Institutes, Taipei, TaiwanK. S. Tsai, Department of Laboratory Medicine, National Taiwan University Hospital, Taipei, TaiwanS. T. Tu, Division of Endocrinology and Metabolism, Changhua Christian Hospital, Changhua, TaiwanJ. S. Wu, Department of Family Medicine, National Cheng Kung University, Tainan, TaiwanC. I. Chang, Division of Geriatric Research, Institute of Population Health Sciences,... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5212381 Thu, 08 Sep 2011 05:55:51 +0100 5212381 http://www.medworm.com/index.php?rid=5212384&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F846r583410553rvh%2F Conclusion  Among apparently healthy adult Japanese men, those with higher skin AF had a lower OSI, indicating a relationship between AGE accumulation and bone strength. A long-term prospective study is required to clarify the causality. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00198-011-1753-4Authors H. Momma, Division of Biomedical Engineering for Health and Welfare, Tohoku University Graduate School of Biomedical Engineering, 2-1 Seiryo-machi, Aoba-ku, Sendai, 980-8575 JapanK. Niu, Division of Biomedical Engineering for Health and Welfare, Tohoku University Graduate School of Biomedical Engineering, 2-1 Seiryo-machi, Aoba-ku, Sendai, 980-8575 JapanY. Kobayashi, Department of Medicine and Science in Sports and Exercise, Tohoku Unive... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5212384 Thu, 08 Sep 2011 05:55:49 +0100 5212384 http://www.medworm.com/index.php?rid=5212385&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp123585t512550r0%2F Conclusions  Oral bisphosphonates are the primary drugs used to treat osteoporosis in Canada. Prescribing practices changed over time as newer medications came to market, yet access to second-generation bisphosphonates through BC PharmaCare was limited. Implications of differential access to oral bisphosphonates warrants further study. Content Type Journal ArticleCategory Original ArticlePages 1-6DOI 10.1007/s00198-011-1771-2Authors S. M. Cadarette, Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, M5S 3M2 ON, CanadaG. Carney, Therapeutics Initiative, University of British Columbia, Victoria, BC, CanadaD. Baek, Leslie Dan Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, M5S 3M2 ON, CanadaN. Gunraj, Institute f... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5212385 Thu, 08 Sep 2011 05:55:48 +0100 5212385 http://www.medworm.com/index.php?rid=5212386&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx8286811l5772866%2F Conclusion  HIV/HCV-co-infected men have compromised hip strength at the narrow neck compared to uninfected controls, which is attributable in large part to lower lean body mass. Content Type Journal ArticleCategory Original ArticlePages 1-9DOI 10.1007/s00198-011-1769-9Authors V. Walker Harris, Johns Hopkins University School of Medicine, Baltimore, MD, USAC. G. Sutcliffe, Johns Hopkins School of Public Health, Baltimore, MD, USAA. B. Araujo, New England Research Institutes, Watertown, MA, USAG. R. Chiu, New England Research Institutes, Watertown, MA, USAT. G. Travison, Boston University, Boston, MA, USAS. Mehta, Johns Hopkins School of Public Health, Baltimore, MD, USAM. S. Sulkowski, Johns Hopkins University School of Medicine, Baltimore, MD, USAY. Higgins, Johns Ho... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5212386 Thu, 08 Sep 2011 05:55:47 +0100 5212386 http://www.medworm.com/index.php?rid=5198322&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj24k856v159279j9%2F Conclusions  Among the growing population of Canadian seniors, falls have substantial costs. With the cost of a fall-related hospitalization approaching $30,000, there is an increased need for fall prevention programs. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00198-011-1764-1Authors J. C. Woolcott, Faculty of Pharmaceutical Sciences, University of British Columbia, Vancouver, CanadaK. M. Khan, Centre for Hip Health and Mobility, Vancouver Coastal Research Institute, Vancouver, CanadaS. Mitrovic, Faculty of Medicine, University of British Columbia, Vancouver, CanadaA. H. Anis, Centre for Health Evaluation and Outcome Sciences, Providence Health Research Institute, Vancouver, CanadaC. A. Marra, Faculty of Pharmaceutical Sciences, Univer... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5198322 Sun, 04 Sep 2011 10:53:13 +0100 5198322 http://www.medworm.com/index.php?rid=5198321&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft6r355223w77j303%2F Conclusion  Findings in this study suggested an additive effect of ZA and PTH on fracture healing in OVX rats, and this additive effect was specific to callus formation, not to undisturbed bone tissue. Content Type Journal ArticleCategory Original ArticlePages 1-12DOI 10.1007/s00198-011-1751-6Authors Y. F. Li, The State Key Laboratory of Oral Diseases and Center of Orthognathic Surgery, West China College of Stomatology, Sichuan University, Chengdu, 610041 ChinaC. C. Zhou, The State Key Laboratory of Oral Diseases and Center of Orthognathic Surgery, West China College of Stomatology, Sichuan University, Chengdu, 610041 ChinaJ. H. Li, The State Key Laboratory of Oral Diseases and Center of Orthognathic Surgery, West China College of Stomatology, Sichuan University, Che... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5198321 Sun, 04 Sep 2011 10:53:13 +0100 5198321 http://www.medworm.com/index.php?rid=5198323&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Frx4r278ww1272173%2F Conclusions  This 12-month aerobic jumping and circuit training intervention completely prevented femoral neck bone loss in premenopausal breast cancer patients, whereas no effect on BMD was seen in postmenopausal women. Content Type Journal ArticleCategory Original ArticlePages 1-12DOI 10.1007/s00198-011-1761-4Authors T. Saarto, Department of Oncology, Helsinki University Central Hospital, P.O. Box 180, Helsinki, 00029 HUS, FinlandH. Sievänen, The UKK Institute for Health Promotion Research, Tampere, FinlandP. Kellokumpu-Lehtinen, Department of Oncology, Tampere University Central Hospital, Tampere, FinlandR. Nikander, The UKK Institute for Health Promotion Research, Tampere, FinlandL. Vehmanen, Department of Oncology, Helsinki University Central Hospital, P.O. Box ... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5198323 Sun, 04 Sep 2011 10:53:11 +0100 5198323 http://www.medworm.com/index.php?rid=5198324&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F01r23341w77003h6%2F Conclusions  Serious adverse events of infections that occurred with denosumab treatment had heterogeneous etiology, with no clear clinical pattern to suggest a relationship to time or duration of exposure to denosumab. Content Type Journal ArticleCategory Original ArticlePages 1-11DOI 10.1007/s00198-011-1755-2Authors N. B. Watts, Bone Health and Osteoporosis Center, College of Medicine, University of Cincinnati, 222 Piedmont Avenue, Suite 6300, Cincinnati, OH 45219, USAC. Roux, Paris Descartes University Hôpital Cochin, Paris, FranceJ. F. Modlin, Dartmouth Medical School, Lebanon, NH, USAJ. P. Brown, CHUQ-CHUL, Laval University, Quebec City, QC, CanadaA. Daniels, Amgen Inc., Thousand Oaks, CA, USAS. Jackson, Amgen Inc., Thousand Oaks, CA, USAS. Smith, Amgen Inc., Th... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5198324 Sun, 04 Sep 2011 10:53:09 +0100 5198324 http://www.medworm.com/index.php?rid=5186151&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd74363267326jv54%2F Conclusions  This study suggests that in obese adolescent boys, intertrochanteric structural rigidity and femoral shaft structural rigidity and bending strength are not adapted to the increased body weight. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00198-011-1754-3Authors R. El Hage, Laboratoire de physiologie et de biomécanique de la performance motrice, Université de Balamand, Al Koura, Lebanon Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5186151 Wed, 31 Aug 2011 15:54:02 +0100 5186151 http://www.medworm.com/index.php?rid=5186153&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu38377p1487101v2%2F Conclusions  There was a trend in bone loss during the first 6 months postpartum with posterior recovery. Also, hormonal contraceptive methods provided protection of bone loss. However, the long duration of breastfeeding and the follow-up were not sufficient to draw definitive conclusions on postweaning BMD conditions. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00198-011-1767-yAuthors M. L. Costa, Department of Obstetrics and Gynecology, School of Medical Sciences, University of Campinas, Campinas, BrazilF. G. Krupa, Department of Obstetrics and Gynecology, School of Medical Sciences, University of Campinas, Campinas, BrazilP. M. Rehder, Department of Obstetrics and Gynecology, School of Medical Sciences, University of Campinas, C... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=5186153 Wed, 31 Aug 2011 15:54:01 +0100 5186153