Osteoporosis International via MedWorm.com MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Osteoporosis International' source. Tue, 16 Mar 2010 16:24:03 +0100 Efficacy of low doses of pamidronate in osteopenic patients administered in the early post-renal transplant http://www.medworm.com/index.php?rid=3368376&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv8557273pt350623%2F Conclusion  A low dose of pamidronate prevents bone loss in osteopenic patients when administered immediately after RT. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-010-1197-2Authors J.-V. Torregrosa, Hospital Clínic Barcelona SpainD. Fuster, Hospital Clínic Barcelona SpainA. Monegal, Hospital Clínic Barcelona SpainM. Á. Gentil, Hospital Virgen del Rocío Sevilla SpainJ. Bravo, Hospital Virgen de las Nieves Granada SpainL. Guirado, Fundació Puigvert Barcelona SpainA. Muxí, Hospital Clínic Barcelona SpainJ. Cubero, Hospital Infanta Cristina Badajoz Spain Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3368376 Sun, 14 Mar 2010 11:30:06 +0100 3368376 The role of interleukin-6 in rheumatoid arthritis-associated osteoporosis http://www.medworm.com/index.php?rid=3368375&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm50725282420r39q%2F Conclusion  The development of agents that modulate the actions of IL-6 and those of other pro-inflammatory mediators of bone loss may provide alternative osteoporosis management strategies for patients with RA than existing general osteoporosis therapies. Content Type Journal ArticleCategory ReviewDOI 10.1007/s00198-010-1192-7Authors C. J. Edwards, Southampton University Hospital Department of Rheumatology Tremona Road Southampton SO16 6YD UKE. Williams, Southampton University Hospital Department of Rheumatology Tremona Road Southampton SO16 6YD UK Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3368375 Sun, 14 Mar 2010 11:30:06 +0100 3368375 Patterns of treatment in Australian men following fracture http://www.medworm.com/index.php?rid=3368377&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fcn65770238m2u71k%2F Conclusions  Our findings are consistent with previously published data showing low rates of treatment initiation in men eligible for osteoporosis treatment. There appear to be barriers involving participants’ and medical practitioners’ knowledge, beliefs and attitudes regarding osteoporosis and treatment, as well as in the doctor–patient partnership in osteoporosis management. Establishment of clinical pathways for fracture management beyond orthopaedic care may be one of a range of appropriate responses. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-010-1204-7Authors R. Otmar, The University of Melbourne Department of Clinical and Biomedical Sciences: Barwon Health PO Box 281 Geelong 3220 AustraliaM. J. Henry, The University of Mel... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3368377 Sun, 14 Mar 2010 11:30:05 +0100 3368377 Osteocyte: the unrecognized side of bone tissue http://www.medworm.com/index.php?rid=3356621&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh06k7772458717g0%2F Discussion  The mechanical information transmitted into the cytoplasm also triggers a biological cascade, starting with NO and PGE2 and followed by Wnt/β catenin signaling. This information is transmitted to the bone surface through the canalicular network, particularly to the lining cells, and is able to trigger bone remodeling by directing the osteoblast activity and the osteoclastic resorption. Furthermore, the osteocyte death seems to play also an important role. The outcome of micro-cracks in the vicinity of osteocytes may interrupt the canalicular network and trigger cell apoptosis in the immediate surrounding environment. This apoptosis appears to transmit a message to the bone surface and activate remodeling. The osteocyte network also plays a recognized endocrine r... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3356621 Wed, 10 Mar 2010 13:23:51 +0100 3356621 Laser 904 nm action on bone repair in rats with osteoporosis http://www.medworm.com/index.php?rid=3356623&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F12uj8l6p26698771%2F Conclusion  Low-level 904-nm laser (50 mJ/cm2) accelerated the repair process of osteopenic fractures, especially in the initial phase of bone regeneration. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-010-1183-8Authors D. A. A. Pires-Oliveira, Universidade Camilo Castelo Branco—Unicastelo São Paulo Programa de Pós Graduação—Unicastelo, Departamento Curso de Odontologia Rua Carolina Fonseca 584, Itaquera São Paulo São Paulo CEP-08.230-030 BrazilR. F. Oliveira, Universidade Camilo Castelo Branco—Unicastelo São Paulo Programa de Pós Graduação—Unicastelo, Departamento Curso de Odontologia Rua Carolina Fonseca 584, Itaquera São Paulo São Paulo CEP-08.230-030 BrazilS. U. Amadei, Faculdade de Pindamonhangaba—Fapi Rodovia ... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3356623 Wed, 10 Mar 2010 13:23:48 +0100 3356623 Race/ethnic differences in bone mineral densities in older men http://www.medworm.com/index.php?rid=3356626&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff76543825371tg1r%2F Conclusion  These findings show substantial race/ethnic differences in BMD even within African or Asian origin and illustrate the important role of body size on the difference between Asian men and others. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-010-1188-3Authors H.-S. Nam, Chungnam National University College of Medicine Department of Preventive Medicine, Research Institute for Medical Sciences Daejeon South KoreaM.-H. Shin, Chonnam National University Medical School Department of Preventive Medicine Gwangju South KoreaJ. M. Zmuda, University of Pittsburgh Department of Epidemiology, Graduate School of Public Health 130 DeSoto Street, Crabtree Hall A524 Pittsburgh PA 15261 USAP. C. Leung, Chinese University of Hong Kong, Prince of Wale... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3356626 Wed, 10 Mar 2010 13:23:47 +0100 3356626 Depression, fracture risk, and bone loss: a meta-analysis of cohort studies http://www.medworm.com/index.php?rid=3356625&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp7u331632m82624w%2F Conclusion  Evidence supports an association between depression and increased risk of fracture and bone loss that may be mediated by antidepressants. Content Type Journal ArticleCategory ReviewDOI 10.1007/s00198-010-1181-xAuthors Q. Wu, Mayo Clinic College of Medicine 13400 East Shea Boulevard Scottsdale AZ 85259 USAJ. Liu, Arizona State University College of Liberal Arts and Sciences Tempe AZ USAJ. F. Gallegos-Orozco, Mayo Clinic College of Medicine 13400 East Shea Boulevard Scottsdale AZ 85259 USAJ. G. Hentz, Mayo Clinic College of Medicine 13400 East Shea Boulevard Scottsdale AZ 85259 USA Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3356625 Wed, 10 Mar 2010 13:23:47 +0100 3356625 Functional data modelling approach for analysing and predicting trends in incidence rates—an application to falls injury http://www.medworm.com/index.php?rid=3356624&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F066478009g3885x0%2F Conclusions  In summary, FDA provides more accurate predictions of long-term incidence trends than commonly used methods. The production of FDA prediction intervals for future injury incidence rates gives likely guidance as to the likely accuracy of these predictions. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-010-1189-2Authors S. Ullah, University of Ballarat School of Human Movement and Sport Sciences Mt Helen VIC 3353 AustraliaC. F. Finch, University of Ballarat School of Human Movement and Sport Sciences Mt Helen VIC 3353 Australia Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3356624 Wed, 10 Mar 2010 13:23:47 +0100 3356624 Strontium ranelate decreases the incidence of new caudal vertebral fractures in a growing mouse model with spontaneous fractures by improving bone microarchitecture http://www.medworm.com/index.php?rid=3356628&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn111645127507114%2F Conclusions  This model allows, for the first time, direct assessment of anti-fracture efficacy of strontium ranelate treatment in rodents. In these transgenic mice, strontium ranelate was able to decrease caudal vertebral fracture incidence through an improvement of trabecular and cortical architecture. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-010-1193-6Authors V. Geoffroy, University Paris 7, Hôpital Lariboisière INSERM U606 Paris FranceD. Chappard, INSERM U922 Angers FranceC. Marty, University Paris 7, Hôpital Lariboisière INSERM U606 Paris FranceH. Libouban, INSERM U922 Angers FranceA. Ostertag, University Paris 7, Hôpital Lariboisière INSERM U606 Paris FranceA. Lalande, Institut de Recherche International Servier Courbevoie F... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3356628 Wed, 10 Mar 2010 13:23:46 +0100 3356628 Circulating osteocalcin concentrations are associated with parameters of liver fat infiltration and increase in parallel to decreased liver enzymes after weight loss http://www.medworm.com/index.php?rid=3356627&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fxh33704351688r08%2F Conclusions  In summary, our findings suggest a bone–liver axis in which osteocalcin might be the active regulator. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-010-1174-9Authors J. M. Fernández-Real, Institut d’Investigació Biomédica de Girona (IdIBGi) CIBEROBN Fisiopatología de la Obesidad y Nutrición CB06/03/010 Department of Diabetes, Endocrinology and Nutrition Girona Catalonia SpainF. Ortega, Institut d’Investigació Biomédica de Girona (IdIBGi) CIBEROBN Fisiopatología de la Obesidad y Nutrición CB06/03/010 Department of Diabetes, Endocrinology and Nutrition Girona Catalonia SpainJ. Gómez-Ambrosi, University of Navarra Department of Endocrinology Pamplona SpainJ. Salvador, University of Navarra Department of Endocrinology P... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3356627 Wed, 10 Mar 2010 13:23:46 +0100 3356627 To investigate the role of the nervous system of bone in steroid-induced osteonecrosis in rabbits http://www.medworm.com/index.php?rid=3356629&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw08027l60t305268%2F Conclusion  This study showed that osteonecrosis in rabbits is chronologically associated with changes in neural factors. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1159-8Authors L. Wang, Xi’an Jiaotong University Department of Orthopedic Surgery, Second Affiliated Hospital of Medical College Xi’an 710061 People’s Republic of ChinaN. Wang, Anhui Medical University Department of Anatomy Hefei People’s Republic of ChinaM. Li, Xi’an Jiaotong University Department of Anatomy of Medical College Xi’an People’s Republic of ChinaK. Wang, Xi’an Jiaotong University Department of Orthopedic Surgery, Second Affiliated Hospital of Medical College Xi’an 710061 People’s Republic of China Journal Osteoporosis InternationalOnlin... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3356629 Wed, 10 Mar 2010 13:23:45 +0100 3356629 Effect of calcium and vitamin D supplementation on bone mineral density in women aged 65–71 years: a 3-year randomized population-based trial (OSTPRE-FPS) http://www.medworm.com/index.php?rid=3356630&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm016330581332017%2F Conclusion  Daily vitamin D and calcium supplementation have a positive effect on the skeleton in ambulatory postmenopausal women with adequate nutritional calcium intake. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1167-8Authors M. Kärkkäinen, University of Kuopio Bone and Cartilage Research Unit, Mediteknia Building P.O. Box 1627 70211 Kuopio FinlandM. Tuppurainen, University of Kuopio Bone and Cartilage Research Unit, Mediteknia Building P.O. Box 1627 70211 Kuopio FinlandK. Salovaara, University of Kuopio Bone and Cartilage Research Unit, Mediteknia Building P.O. Box 1627 70211 Kuopio FinlandL. Sandini, Kuopio University Hospital, Kuopio University Hospital Department of Internal Medicine Kuopio FinlandT. Rikkonen, University of... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3356630 Wed, 10 Mar 2010 13:23:44 +0100 3356630 The hormonal profile of hip fracture female patients differs from community-dwelling peers over a 1-year follow-up period http://www.medworm.com/index.php?rid=3356631&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc012026j2x8874t7%2F Conclusions  Older women who have sustained a hip fracture have progressive changes in hormonal milieu that exceed those of women of similar health status during the year following fracture. Content Type Journal ArticleCategory Short CommunicationDOI 10.1007/s00198-010-1187-4Authors A. R. Cappola, University of Pennsylvania School of Medicine Division of Endocrinology, Diabetes and Metabolism 764 CRB, 415 Curie Blvd. Philadelphia PA 19104 USAW. G. Hawkes, University of Maryland Division of Gerontology, Department of Epidemiology and Preventive Medicine Baltimore MD USAN. Blocher, Albert Einstein Medical Center Division of Endocrinology Philadelphia PA USAJ. Yu-Yahiro, The Union Memorial Hospital Department of Orthopaedic Surgery Baltimore MD USAD. Orwig, University of... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3356631 Wed, 10 Mar 2010 13:23:41 +0100 3356631 Comparison of the effects of alendronate sodium and calcitonin on bone–prosthesis osseointegration in osteoporotic rats http://www.medworm.com/index.php?rid=3356633&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk3807h37xl185wp1%2F Conclusions  In osteoporotic conditions, both administration of ALO orally and CT subcutaneously can enhance periprosthesis bone mass and the effects on osseointegration between host bone and prosthesis. Compared with CT, the effect of ALO is more pronounced. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-010-1186-5Authors B.-L. Chen, First Affiliated Hospital of Sun Yat-sen University Department of Orthopaedics 58 Zhongshan Second Road Guangzhou 510080 ChinaD.-H. Xie, First Affiliated Hospital of Sun Yat-sen University Department of Orthopaedics 58 Zhongshan Second Road Guangzhou 510080 ChinaZ.-M. Zheng, First Affiliated Hospital of Sun Yat-sen University Department of Orthopaedics 58 Zhongshan Second Road Guangzhou 510080 ChinaW. Lu, Univers... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3356633 Wed, 10 Mar 2010 13:23:40 +0100 3356633 Erratum to: Morphological changes of injected calcium phosphate cement in osteoporotic compressed vertebral bodies http://www.medworm.com/index.php?rid=3356632&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu6579v3257624382%2F Content Type Journal ArticleCategory ErratumDOI 10.1007/s00198-009-1148-yAuthors D. H. Heo, Hallym University Department of Neurosurgery, Chuncheon Sacred Heart Hospital, College of Medicine 153 Kyo-dong, Chuncheon Kangwon-do South KoreaY. J. Cho, Hallym University Department of Neurosurgery, Chuncheon Sacred Heart Hospital, College of Medicine 153 Kyo-dong, Chuncheon Kangwon-do South KoreaS. H. Sheen, Hallym University Department of Neurosurgery, Chuncheon Sacred Heart Hospital, College of Medicine 153 Kyo-dong, Chuncheon Kangwon-do South KoreaS. U. Kuh, Yonsei University College of Medicine Department of Neurosurgery, Spine, and Spinal Cord Institute Seoul South KoreaS. M. Cho, Hallym University Department of Neurosurgery, Chuncheon Sacred Heart Hospital, College of Medicine 153 Kyo-... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3356632 Wed, 10 Mar 2010 13:23:40 +0100 3356632 Dose–response effect of 40 weeks of resistance training on bone mineral density in older adults http://www.medworm.com/index.php?rid=3329304&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq3211614g6n205x1%2F Conclusions  The resistance training programs, regardless of intensity and frequency, were effective in improving BMD of the proximal femur and lumbar spine but not the total body. Both men and women responded similarly for the hip sites but men show a greater response at the lumbar spine than women. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-010-1182-9Authors D. A. Bemben, University of Oklahoma Bone Density Research Laboratory, Department of Health and Exercise Science Norman OK 73019 USAM. G. Bemben, University of Oklahoma Bone Density Research Laboratory, Department of Health and Exercise Science Norman OK 73019 USA Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3329304 Tue, 02 Mar 2010 09:59:27 +0100 3329304 Severity of vertebral fracture and risk of hip fracture: a nested case–control study http://www.medworm.com/index.php?rid=3329305&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F8242lp3217gv1731%2F Conclusions  The presence of a severe vertebral fracture in the thoracic spine strongly predicts subsequent hip fracture. Such high-risk patients should be clinically evaluated and provided with care for osteoporosis and measures to reduce the risk of falling as required. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-010-1195-4Authors V. Puisto, National Institute for Health and Welfare Helsinki FinlandM. Heliövaara, National Institute for Health and Welfare Helsinki FinlandO. Impivaara, National Institute for Health and Welfare Helsinki FinlandT. Jalanko, Helsinki University Central Hospital Hospital for Children and Adolescents Helsinki FinlandH. Kröger, Kuopio University Hospital Kuopio FinlandP. Knekt, National Institute for Health and... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3329305 Tue, 02 Mar 2010 09:59:26 +0100 3329305 Oral contraceptive use and bone mass in women aged 26–36 years http://www.medworm.com/index.php?rid=3329306&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy67213x218372383%2F Conclusion  Combined oral contraceptive use was associated with higher bone mass measured by quantitative ultrasound in this population-based sample of premenopausal women aged 26–36 while progestogen-only contraceptives appeared to have no deleterious effect on bone mass. Content Type Journal ArticleCategory Short CommunicationDOI 10.1007/s00198-010-1180-yAuthors S. Wei, University of Tasmania Menzies Research Institute Private bag 23 Hobart Tasmania 7001 AustraliaG. Jones, University of Tasmania Menzies Research Institute Private bag 23 Hobart Tasmania 7001 AustraliaR. Thomson, University of Tasmania Menzies Research Institute Private bag 23 Hobart Tasmania 7001 AustraliaT. Dwyer, Murdoch Children’s Research Institute Parkville Victoria 3052 AustraliaA. Venn, U... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3329306 Tue, 02 Mar 2010 09:59:25 +0100 3329306 International comparison of cost of falls in older adults living in the community: a systematic review http://www.medworm.com/index.php?rid=3329307&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx23h84582l7mq428%2F Conclusions  The economic cost of falls is likely greater than policy makers appreciate. The mean cost of falls was dependent on the denominator used and ranged from US 3,476 per faller to US10,749 per injurious fall and US $26,483 per fall requiring hospitalization. A consensus on methodology for cost of falls studies would enable more accurate comparisons and subgroup-specific estimates among different countries. Content Type Journal ArticleCategory ReviewDOI 10.1007/s00198-009-1162-0Authors J. C. Davis, University of British Columbia Centre for Hip Health and Mobility Vancouver CanadaM. C. Robertson, University of Otago Department of Medical & Surgical Sciences, Dunedin School of Medicine Dunedin New ZealandM. C. Ashe, University of British Columbia Centre for Hi... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3329307 Tue, 02 Mar 2010 09:59:23 +0100 3329307 Serum undercarboxylated osteocalcin was inversely associated with plasma glucose level and fat mass in type 2 diabetes mellitus http://www.medworm.com/index.php?rid=3285878&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff7583q2114405422%2F Conclusions  These findings suggest that ucOC is associated with plasma glucose level and fat mass in men with type 2 diabetes. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-010-1184-7Authors I. Kanazawa, Shimane University Department of Internal Medicine 1, Faculty of Medicine 89-1 Enya-cho Izumo Shimane 693-8501 JapanT. Yamaguchi, Shimane University Department of Internal Medicine 1, Faculty of Medicine 89-1 Enya-cho Izumo Shimane 693-8501 JapanM. Yamauchi, Shimane University Department of Internal Medicine 1, Faculty of Medicine 89-1 Enya-cho Izumo Shimane 693-8501 JapanM. Yamamoto, Shimane University Department of Internal Medicine 1, Faculty of Medicine 89-1 Enya-cho Izumo Shimane 693-8501 JapanS. Kurioka, Shimane University Department of I... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3285878 Wed, 17 Feb 2010 18:26:48 +0100 3285878 Risk of subsequent fracture and mortality within 5 years after a non-vertebral fracture http://www.medworm.com/index.php?rid=3281700&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F4881376w56852407%2F Conclusions  Within 5 years after an initial NVF, nearly one in five patients sustained a subsequent NVF and one in three died. One third of subsequent NVFs and mortality occurred within 1 year, indicating the need to study which reversible factors can be targeted to immediately prevent subsequent fractures and mortality. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-010-1178-5Authors K. M. B. Huntjens, Maastricht University Medical Centre Department of Trauma Surgery P. Debyelaan 25 P.O. Box 5800 6202 AZ Maastricht The NetherlandsS. Kosar, Maastricht University Medical Centre Department of Trauma Surgery P. Debyelaan 25 P.O. Box 5800 6202 AZ Maastricht The NetherlandsT. A. C. M. van Geel, School for Public Health and Primary Car... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3281700 Tue, 16 Feb 2010 18:04:56 +0100 3281700 Validation of a 5-year risk score of hip fracture in postmenopausal women. The Danish Nurse Cohort Study http://www.medworm.com/index.php?rid=3281701&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy02603701816u230%2F Conclusions  While the WHI algorithm was well calibrated on the Danish population, the clinical utility of the WHI algorithm in Danish postmenopausal women was limited by poor sensitivity at common decision-making thresholds and suboptimal in non-HT-users. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-010-1176-7Authors Y. A. Hundrup, Glostrup University Hospital Research Centre for Prevention and Health, The Capital Region of Denmark Ndr. Ringvej 57, Building 84/85 DK 2600 Glostrup DenmarkR. K. Jacobsen, Glostrup University Hospital Research Centre for Prevention and Health, The Capital Region of Denmark Ndr. Ringvej 57, Building 84/85 DK 2600 Glostrup DenmarkA. H. Andreasen, Glostrup University Hospital Research Centre for Prevention and Hea... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3281701 Tue, 16 Feb 2010 07:18:46 +0100 3281701 Effects of 25-hydroxyvitamin D level and its change on parathyroid hormone in premenopausal Chinese women http://www.medworm.com/index.php?rid=3274413&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fqt712550765xv163%2F Conclusions  We conclude that vitamin D deficiency is common in young women in Hong Kong. The cross-sectional analysis indicates that optimal 25(OH)D is >40 nmol/L, and the longitudinal data is consistent with a higher optimal value which is not defined in this study’s results. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1163-zAuthors C. J. Bacon, University of Auckland Department of Medicine Auckland New ZealandJ. Woo, The Chinese University of Hong Kong Department of Medicine and Therapeutics Hong Kong ChinaE. M. C. Lau, Hong Kong Orthopaedic and Osteoporosis Center for Treatment and Research Hong Kong ChinaC. W. K. Lam, The Chinese University of Hong Kong Department of Chemical Pathology Hong Kong ChinaG. D. Gamble, Universi... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3274413 Sat, 13 Feb 2010 06:50:49 +0100 3274413 Filtering FRAX® http://www.medworm.com/index.php?rid=3270588&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F6q8hg13849q57g66%2F Content Type Journal ArticleCategory For DebateDOI 10.1007/s00198-009-1104-x Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3270588 Fri, 12 Feb 2010 07:06:18 +0100 3270588 Reduced cortical bone density with normal trabecular bone density in girls with Turner syndrome http://www.medworm.com/index.php?rid=3248047&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb770616124114356%2F This study of 22 girls with Turner syndrome (TS) demonstrates a reduction in bone mineral apparent density (BMAD) at the femoral neck along with a reduction in cortical bone density at the radius (with sparing of trabecular bone). These findings may account for the increased fracture risk noted in this population. Introduction  Increased fracture risk is a feature of TS; however, the reasons for this are unclear. Little is known regarding cortical and trabecular bone mineral density (BMD) in TS. We have addressed this by measurement of volumetric bone mineral density (vBMD) using peripheral quantitative computed tomography (pQCT). Methods  We studied 22 females with TS and 21 females without TS; mean ages 12.7 and 12.9 years, respectively. Bone ma... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3248047 Fri, 05 Feb 2010 08:33:40 +0100 3248047 Detection of vertebral fractures in DXA VFA images using statistical models of appearance and a semi-automatic segmentation http://www.medworm.com/index.php?rid=3248046&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk10527k13lk00828%2F Conclusion  Specificity and sensitivity are improved by using an appearance-based classifier compared to standard height ratio morphometry. An overall sensitivity loss of 7% occurs (at 95% specificity) when using a semi-automatic (AAM) segmentation compared to expert annotation, due to segmentation error. However, the classifier sensitivity is still adequate for a computer-assisted diagnosis system for vertebral fracture, especially if used in a triage approach. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1169-6Authors M. G. Roberts, University of Manchester Imaging Science and Biomedical Engineering Stopford Building, Oxford Road Manchester M13 9PT UKE. M. B. Pacheco, University of Manchester Imaging Science and Biomedical Engineering ... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3248046 Fri, 05 Feb 2010 08:33:40 +0100 3248046 Effects of bone mineral density of the lumbar spine and prevalent vertebral fractures on the risk of immobility http://www.medworm.com/index.php?rid=3248048&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr5p02746m401200t%2F Conclusion  These results indicate that low BMD and prevalent vertebral fracture pose an independent risk for future immobilization in postmenopausal Japanese women. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1121-9Authors M. Shiraki, Research Institute and Practice for Involutional Diseases Nagano JapanT. Kuroda, Tokyo Women’s Medical University Department of Gynecology and Obstetrics Tokyo JapanY. Shiraki, Research Institute and Practice for Involutional Diseases Nagano JapanC. Aoki, Research Institute and Practice for Involutional Diseases Nagano JapanK. Sasaki, Research Institute and Practice for Involutional Diseases Nagano JapanS. Tanaka, Kyoto University Division of Clinical Trial, Design and Management, Translational Research C... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3248048 Thu, 04 Feb 2010 18:08:38 +0100 3248048 Histomorphometric changes by teriparatide in alendronate-pretreated women with osteoporosis http://www.medworm.com/index.php?rid=3248050&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg835655k701187u6%2F Conclusions  The increased level of formation is similar in patients who were either TN or had lower bone turnover initially due to previous ALN therapy. Elevated bone formation in postmenopausal women with osteoporosis was sustained over a 24-month period by TPTD. Biochemical markers of bone formation are a good surrogate for the assessment of TPTD effects. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1168-7Authors J. J. Stepan, Charles University Institute of Rheumatology, Faculty of Medicine Na Slupi 4 CZ12850 Prague Czech RepublicD. B. Burr, Indiana University School of Medicine Department of Anatomy and Cell Biology Indianapolis IN USAJ. Li, Indiana University–Purdue University Indianapolis Department of Biology Indianapolis IN USA... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3248050 Thu, 04 Feb 2010 18:08:37 +0100 3248050 Does using lower limit of normal values enhance the ability of a single bone mineral density measure to predict fractures? http://www.medworm.com/index.php?rid=3248049&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F9w78235652ur7864%2F Conclusion  The LLN method provides a more consistent and efficient method for osteoporosis fracture prediction than the T-score in 67- to 74-year-old white women. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1160-2Authors Q. Wu, Mayo Clinic Biostatistics 13400 East Shea Blvd Scottsdale AZ 85259 USAJ. H. Magnus, Department of Community Health Sciences, Tulane University School of Public Health and Tropical Medicine, and Department of Medicine, Tulane University School of Medicine Suite 2300 1440 Canal Street New Orleans LA 70112 USAJ. C. Rice, Tulane University School of Public Health and Tropical Medicine Department of Biostatistics Suite 2100 1440 Canal Street New Orleans LA 70112 USAJ. J. Lefante, Tulane University School of Public Heal... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3248049 Thu, 04 Feb 2010 18:08:37 +0100 3248049 Reduced tibial speed of sound in Chinese infants at birth compared with Caucasian peers: the effects of race, gender, and vitamin D on fetal bone development http://www.medworm.com/index.php?rid=3248052&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F03h13p10166826v6%2F Conclusions  Chinese neonates have lower SOS which is influenced by gender, gestational age, season of birth, and maternal vitamin D status. It is inferred that, in pace with gestational age, race and gender effects on fetal bone development are modified by materno-fetal vitamin D status. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1158-9Authors X. P. Liao, Shanghai Jiao Tong University School of Medicine Xinhua Hospital, Shanghai Institute for Pediatric Research, Shanghai Key Laboratory of Children’s Environmental Health 1665 Kong Jiang Road Shanghai 200092 ChinaW. L. Zhang, Shanghai Jiao Tong University School of Medicine Xinhua Hospital, Shanghai Institute for Pediatric Research, Division of Nutrition Shanghai ChinaC. H. Yan, Shangh... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3248052 Thu, 04 Feb 2010 18:08:36 +0100 3248052 Erratum to: Increased risk of serious infections in women with osteopenia or osteoporosis treated with denosumab http://www.medworm.com/index.php?rid=3248051&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F8350485121pl2384%2F Content Type Journal ArticleCategory ErratumDOI 10.1007/s00198-010-1173-xAuthors K. A. Toulis, Aristotle University of Thessaloniki Division of Endocrinology and Metabolism, Medical School Antheon 2, Agios Pavlos Thessaloniki 55438 GreeceA. D. Anastasilakis, 424 General Military Hospital Division of Endocrinology & Metabolism Thessaloniki Greece Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3248051 Thu, 04 Feb 2010 18:08:36 +0100 3248051 Baseline atherosclerosis parameter could assess the risk of bone loss during pioglitazone treatment in type 2 diabetes mellitus http://www.medworm.com/index.php?rid=3248053&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl0826r536535062p%2F Conclusions  Baseline IMT, uNTX, and IGF-I could assess the risk of BMD reduction in diabetic patients treated with pioglitazone. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1161-1Authors I. Kanazawa, Shimane University Faculty of Medicine Department of Internal Medicine 1 89-1 Enya-cho Izumo Shimane 693-8501 JapanT. Yamaguchi, Shimane University Faculty of Medicine Department of Internal Medicine 1 89-1 Enya-cho Izumo Shimane 693-8501 JapanS. Yano, Shimane University Faculty of Medicine Department of Internal Medicine 1 89-1 Enya-cho Izumo Shimane 693-8501 JapanM. Yamamoto, Shimane University Faculty of Medicine Department of Internal Medicine 1 89-1 Enya-cho Izumo Shimane 693-8501 JapanM. Yamauchi, Shimane University Faculty of Medicine ... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3248053 Thu, 04 Feb 2010 06:43:20 +0100 3248053 Incidence and risk factors of falling in ambulatory patients with rheumatoid arthritis: a prospective 1-year study http://www.medworm.com/index.php?rid=3229614&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj3288q24m1303r67%2F Conclusion  We concluded that fall rates in RA patients were higher than in the general population and that balance impairment or side effects of drugs may play a role in increasing the risk of falls. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1150-4Authors M. Hayashibara, Tottori University Department of Orthopedic Surgery, Faculty of Medicine Yonago Tottori 683-8504 JapanH. Hagino, Tottori University School of Health Science, Faculty of Medicine Yonago JapanH. Katagiri, Tottori University Hospital Rehabilitation Division Yonago JapanT. Okano, Tottori University Department of Orthopedic Surgery, Faculty of Medicine Yonago Tottori 683-8504 JapanJ. Okada, Tottori University Department of Radiology, Faculty of Medicine Yonago JapanR. Teshi... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3229614 Fri, 29 Jan 2010 17:57:22 +0100 3229614 The effects of strontium ranelate on biochemical markers of bone turnover and their relationship with bone mineral density http://www.medworm.com/index.php?rid=3224192&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy08w45724r0352h3%2F Content Type Journal ArticleCategory LetterDOI 10.1007/s00198-009-1157-xAuthors J. Stepan, Charles University Faculty of Medicine Prague Czech RepublicS. Ish-Shalom, Technion Faculty of Medicine Bone and Mineral Metabolism Unit, Rambam Health Care Campus Haifa IsraelF. Hawkins, Hospital 12 de Octubre Department of Endocrinology Madrid SpainF. Marín, Lilly Research Centre Windlesham UKJ. Farrerons, Hospital Santa Creu i Sant Pau Internal Medicine Barcelona SpainG. Kapetanos, Aristotelion University Orthopedic Surgery Thessaloniki Greece Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3224192 Wed, 27 Jan 2010 20:22:21 +0100 3224192 The effects of strontium ranelate on biochemical markers of bone turnover and their relationship with bone mineral density: reply to Stepan et al. http://www.medworm.com/index.php?rid=3224193&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff7403814752704q7%2F Content Type Journal ArticleCategory LetterDOI 10.1007/s00198-009-1156-yAuthors O. Bruyere, University of Liège Department of Public Health, Epidemiology and Health Economics, CHU Sart-Tilman Bât B23 4000 Liège BelgiumJ. Collette, University of Liège Department of Public Health, Epidemiology and Health Economics, CHU Sart-Tilman Bât B23 4000 Liège BelgiumJ.-Y. Reginster, University of Liège Department of Public Health, Epidemiology and Health Economics, CHU Sart-Tilman Bât B23 4000 Liège Belgium Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3224193 Wed, 27 Jan 2010 20:22:19 +0100 3224193 Bone mineral density and prevalent osteoarthritis of the hip in older men for the Osteoporotic Fractures in Men (MrOS) Study Group http://www.medworm.com/index.php?rid=3210357&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn7323j3205w56333%2F Conclusion  Older men, with both moderate and severe RHOA, had significantly higher aBMD and integral vBMD at the hip and lumbar spine compared to controls without RHOA. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1105-9Authors R. K. Chaganti, University of California at San Francisco San Francisco CA USAN. Parimi, California Pacific Medical Center Research Institute San Francisco CA USAT. Lang, University of California at San Francisco San Francisco CA USAE. Orwoll, Oregon Health Sciences University Portland OR USAM. L. Stefanick, Stanford University Stanford Prevention Research Center, Department of Medicine Palo Alto CA USAM. Nevitt, University of California at San Francisco San Francisco CA USAN. E. Lane, University of California at D... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3210357 Mon, 25 Jan 2010 16:57:47 +0100 3210357 Persistence and switching patterns among women with varied osteoporosis medication histories: 12-month results from POSSIBLE US™ http://www.medworm.com/index.php?rid=3210358&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe30kj70771220n7q%2F Conclusion  Baseline osteoporosis medication transitions were common in the first year of POSSIBLE US™. Participants not on stable therapy at entry, or who reported severe side effects, or had poor physical health status were at higher risk for these transitions. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1133-5Authors A. N. A. Tosteson, Dartmouth Medical School HB 7505 Clinical Research 1 Medical Center Drive Lebanon NH 03756 USAT. P. Do, Amgen Inc 1201 Amgen Court West MS: WAWM 1111 Seattle WA 98119 USAS. W. Wade, Wade Outcomes Research and Consulting 136 U Street Salt Lake City UT 84103 USAM. S. Anthony, Amgen Inc One Amgen Center Drive MS: 24-2-A Thousand Oaks CA 91320 USAR. W. Downs, Virginia Commonwealth University School of Medi... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3210358 Mon, 25 Jan 2010 16:57:46 +0100 3210358 Therapy of hypoparathyroidism with intact parathyroid hormone http://www.medworm.com/index.php?rid=3206778&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F0453t74175662122%2F Conclusion  PTH(1–84) treatment in hypoparathyroidism significantly reduces supplemental calcium and 1,25-dihydroxyvitamin D requirements without generally altering serum and urinary calcium levels. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1149-xAuthors M. R. Rubin, Columbia University Department of Medicine, Division of Endocrinology, Metabolic Bone Diseases Unit, College of Physicians and Surgeons 630 W. 168th St. New York NY 10032 USAJ. Sliney, Columbia University Department of Medicine, Division of Endocrinology, Metabolic Bone Diseases Unit, College of Physicians and Surgeons 630 W. 168th St. New York NY 10032 USAD. J. McMahon, Columbia University Department of Medicine, Division of Endocrinology, Metabolic Bone Diseases Unit, C... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3206778 Fri, 22 Jan 2010 10:06:59 +0100 3206778 Relative importance of body composition, osteoporosis-related behaviors, and parental income on bone speed of sound in adolescent females http://www.medworm.com/index.php?rid=3206779&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp8l11m5333147185%2F Conclusions  Bone SOS is reduced in adolescent females with increased adiposity, whereas it is positively influenced by oral contraceptives and daily calcium intake. Content Type Journal ArticleCategory Short CommunicationDOI 10.1007/s00198-009-1152-2Authors B. L. Holmes, Brock University Faculty of Applied Health Sciences St. Catharines ON CanadaI. A. Ludwa, Brock University Faculty of Applied Health Sciences St. Catharines ON CanadaK. L. Gammage, Brock University Faculty of Applied Health Sciences St. Catharines ON CanadaD. E. Mack, Brock University Faculty of Applied Health Sciences St. Catharines ON CanadaP. Klentrou, Brock University Faculty of Applied Health Sciences St. Catharines ON Canada Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN ... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3206779 Fri, 22 Jan 2010 10:06:57 +0100 3206779 Effects of a 1-year randomized controlled trial of resistance training on lower limb bone and muscle structure and function in older men http://www.medworm.com/index.php?rid=3206780&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft97j970713tp4614%2F Conclusions  In contrast to previous findings in older women, in older men, a resistance training program does not increase hip bone mass more than walking 30 min three times a week. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1132-6Authors J. Whiteford, Curtin University of Technology Curtin Health Innovation Research Institute, School of Public Health GPO Box U1987 Bentley WA 6845 AustraliaT. R. Ackland, The University of Western Australia School of Sport Science, Exercise and Health Perth WA AustraliaS. S. Dhaliwal, Curtin University of Technology Curtin Health Innovation Research Institute, School of Public Health GPO Box U1987 Bentley WA 6845 AustraliaA. P. James, Curtin University of Technology Curtin Health Innovation Research... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3206780 Fri, 22 Jan 2010 02:58:33 +0100 3206780 Positive impact of compliance to strontium ranelate on the risk of nonvertebral osteoporotic fractures http://www.medworm.com/index.php?rid=3191462&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F8227311375364553%2F Conclusion  Our analyses emphasize the importance of good compliance to treatment in order to reduce the risk of osteoporotic fractures. In particular, there was a greater reduction in the risk of nonvertebral and hip fractures with increase compliance. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1155-zAuthors V. Rabenda, University of Liège Department of Public Health, Epidemiology and Health Economics CHU–Bât. B23 4000 Liège BelgiumJ.-Y. Reginster, University of Liège Department of Public Health, Epidemiology and Health Economics CHU–Bât. B23 4000 Liège Belgium Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3191462 Fri, 15 Jan 2010 17:57:48 +0100 3191462 Outdoor air pollution, bone density and self-reported forearm fracture: the Oslo Health Study http://www.medworm.com/index.php?rid=3191463&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F82440gr35682l551%2F Conclusions  In this study, bone health was not associated with long-term exposure to air pollution in women and in men 59/60 years of age. However, a negative association was suggested in elderly men. Further studies with improved measures of air pollution are warranted. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1130-8Authors K. Alver, Norwegian Institute of Public Health PO Box 4404 Nydalen 0403 Oslo NorwayH. E. Meyer, Norwegian Institute of Public Health PO Box 4404 Nydalen 0403 Oslo NorwayJ. A. Falch, Norwegian Institute of Public Health PO Box 4404 Nydalen 0403 Oslo NorwayA. J. Søgaard, Norwegian Institute of Public Health PO Box 4404 Nydalen 0403 Oslo Norway Journal Osteoporosis InternationalOnline ISSN 1433-2965... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3191463 Fri, 15 Jan 2010 00:40:53 +0100 3191463 Synergistic effects of green tea polyphenols and alphacalcidol on chronic inflammation-induced bone loss in female rats http://www.medworm.com/index.php?rid=3169507&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr5l26745083j43mp%2F Conclusion  We conclude that a bone-protective role of GTP plus alphacalcidol during chronic inflammation bone loss may be due to a reduction of oxidative stress damage and inflammation. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1122-8Authors C.-L. Shen, Texas Tech University Health Sciences Center Department of Pathology BB 198, 3601 4th street Lubbock TX 79430-9097 USAJ. K. Yeh, Winthrop-University Hospital Applied Bench Core Laboratory Mineola NY USAJ. J. Cao, USDA ARS Grand Forks Human Nutrition Research Center Grand Forks ND USAO. L. Tatum, Texas Tech University Health Sciences Center Molecular Pathology Program Lubbock TX USAR. Y. Dagda, Texas Tech University Health Sciences Center Department of Pathology BB 198, 3601 4th street L... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3169507 Tue, 12 Jan 2010 18:17:16 +0100 3169507 Significant differences in UK and US female bone density reference ranges http://www.medworm.com/index.php?rid=3161926&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F4552r2p360u14774%2F Conclusions  In general, US spine and hip reference ranges are not suitable for the calculation of Z-scores in UK women. For some research study designs, the differences may significantly influence the pattern of subject recruitment. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1153-1Authors E. Noon, King’s College London Osteoporosis Research Unit, Division of Imaging Sciences London UKS. Singh, Queen Mary College London Cancer Research UK, Wolfson Institute of Preventive Medicine London UKJ. Cuzick, Queen Mary College London Cancer Research UK, Wolfson Institute of Preventive Medicine London UKT. D. Spector, King’s College London Department of Twin Research and Genetic Epidemiology London UKF. M. K. Williams, King’s College London ... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3161926 Fri, 08 Jan 2010 21:36:22 +0100 3161926 Excess mortality after pelvic fractures in institutionalized older people http://www.medworm.com/index.php?rid=3161927&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F311q5207x4178838%2F Conclusion  Pelvic fractures are associated with an increased mortality. These results should encourage the development of preventive measures to reduce this excess mortality. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1154-0Authors K. Rapp, Robert-Bosch-Hospital Department of Clinical Gerontology Auerbachstr. 110 70376 Stuttgart GermanyI. D. Cameron, University of Sydney Rehabilitation Studies Unit, Sydney Medical School Ryde NSW AustraliaS. Kurrle, Hornsby Ku-ring-gai Hospital Division of Rehabilitation and Aged Care Hornsby NSW AustraliaJ. Klenk, Robert-Bosch-Hospital Department of Clinical Gerontology Auerbachstr. 110 70376 Stuttgart GermanyA. Kleiner, Ulm University Institute of Epidemiology Helmholtzstr. 22 89081 Ulm GermanyS. Hein... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3161927 Fri, 08 Jan 2010 09:08:46 +0100 3161927 Comparison of the effects of two resistance training regimens on muscular and bone responses in premenopausal women http://www.medworm.com/index.php?rid=3161928&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh53j461n10784154%2F Conclusions  The resistance training of 28 weeks increased muscle strength in both training groups with no difference in BMD or in the occurrence of muscle damage. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1139-zAuthors A. C. Vanni, Universidade Regional Integrada do Alto Uruguai e das Missões–Campus de Erechim Health Sciences Department Rua: João Risson, 61, Bairro José Bonifácio Erechim Rio Grande do Sul Brazil CEP 99700-000F. Meyer, EsEF, UFRGS Rua Felizardo 750 Porto Alegre Rio Grande do Sul BrazilA. D. R. da Veiga, Universidade Regional Integrada do Alto Uruguai e das Missões–Campus de Erechim Health Sciences Department Rua: João Risson, 61, Bairro José Bonifácio Erechim Rio Grande do Sul Brazil CEP 99700-000V. P. ... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3161928 Fri, 08 Jan 2010 09:08:28 +0100 3161928 Factors affecting short-term precision of musculoskeletal measures using peripheral quantitative computed tomography (pQCT) http://www.medworm.com/index.php?rid=3155014&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj6jq8453726j4678%2F Conclusions  pQCT is a relatively precise technique for the assessment of bone and muscle, but precision is influenced by time between repeat scans and subject anthropometric characteristics. Investigators and clinicians need to be aware of these factors influencing pQCT outcomes as they may influence statistical power in clinical studies and the characterization of change in individual patients. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1151-3Authors R. R. Swinford, Indiana University Department of Physical Therapy, School of Health and Rehabilitation Sciences 1140 W. Michigan St., CF-326 Indianapolis IN 46202 USAS. J. Warden, Indiana University Department of Physical Therapy, School of Health and Rehabilitation Sciences 1140 W. Mich... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3155014 Wed, 06 Jan 2010 06:48:14 +0100 3155014 Anorexia nervosa, osteoporosis and circulating leptin: the missing link http://www.medworm.com/index.php?rid=3155013&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj886r518jn46701g%2F Conclusion  The mechanisms underlying bone loss in AN patients remain unclear and complex, involving hypoestrogenia as well as nutritional factors such as insulin-like growth factor and leptin. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1120-xAuthors I. Legroux-Gérot, University of Lille II Department of Rheumatology 59037 Lille Cédex FranceJ. Vignau, University of Lille II Department of Addictology 59037 Lille Cédex FranceE. Biver, University of Lille II Department of Rheumatology 59037 Lille Cédex FranceP. Pigny, University of Lille II Department of Biology 59037 Lille Cédex FranceF. Collier, University of Lille II Department of Gynaecology 59037 Lille Cédex FranceX. Marchandise, University of Lille II Department of Nuclear Medic... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3155013 Wed, 06 Jan 2010 06:48:14 +0100 3155013 Bone health and deterioration in quality of life among participants from the Hertfordshire cohort study http://www.medworm.com/index.php?rid=3109764&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fur32mm5511822666%2F Conclusions  Men with lower bone density at baseline had poorer quality of life some 4 years later, even after adjustment for co-morbidity and fracture. This may reflect secondary osteoporosis in men (due to alcohol or hypogonadism). Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1147-zAuthors E. M. Dennison, University of Southampton, Southampton General Hospital MRC Epidemiology Resource Centre Southampton SO16 6YD UKK. A. Jameson, University of Southampton, Southampton General Hospital MRC Epidemiology Resource Centre Southampton SO16 6YD UKH. E. Syddall, University of Southampton, Southampton General Hospital MRC Epidemiology Resource Centre Southampton SO16 6YD UKH. J. Martin, University of Southampton, Southampton General Hospital... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3109764 Sat, 19 Dec 2009 06:54:10 +0100 3109764 Effects of high dose of zoledronic acid on superficial vascular network of membranous bone sites: an intravital study on rat calvarium http://www.medworm.com/index.php?rid=3106122&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F525246782j71j481%2F Conclusions  With the help of an original intravital animal model a significant modifications on the total length of the vascular network and the vascular density of small vessels are highlighted on a membranous bone site. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1146-0Authors M. H. Vieillard, University Lille Nord de France, CHRU Lille Department of Rheumatology, Hôpital Roger Salengro 59037 Lille cedex FranceJ. Paccou, University Lille Nord de France, CHRU Lille Department of Rheumatology, Hôpital Roger Salengro 59037 Lille cedex FranceB. Cortet, University Lille Nord de France, CHRU Lille Department of Rheumatology, Hôpital Roger Salengro 59037 Lille cedex FranceE. Biver, University Lille Nord de France, CHRU Lille Department of ... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3106122 Fri, 18 Dec 2009 07:04:43 +0100 3106122 Increased risk of serious infections in women with osteopenia or osteoporosis treated with denosumab http://www.medworm.com/index.php?rid=3098629&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy8773h670374v341%2F Content Type Journal ArticleCategory LetterDOI 10.1007/s00198-009-1145-1Authors K. A. Toulis, Aristotle University of Thessaloniki Division of Endocrinology and Metabolism, Medical School Antheon 2, Agios Pavlos Thessaloniki 55438 GreeceA. D. Anastasilakis, 424 General Military Hospital Division of Endocrinology & Metabolism Thessaloniki Greece Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3098629 Tue, 15 Dec 2009 06:44:52 +0100 3098629 Gonadal sex steroid status and bone health in middle-aged and elderly European men http://www.medworm.com/index.php?rid=3098630&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn12360607610360g%2F Conclusion  Higher free and total E2 are associated with bone health not only among the elderly but also middle-aged European men. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1144-2Authors D. Vanderschueren, Katholieke Universiteit Leuven Department of Andrology and Endocrinology Leuven BelgiumS. R. Pye, The University of Manchester, Manchester Academic Health Science Centre ARC Epidemiology Unit Manchester UKK. Venken, Katholieke Universiteit Leuven Department of Andrology and Endocrinology Leuven BelgiumH. Borghs, Katholieke Universiteit Leuven Leuven University Division of Geriatric Medicine and Centre for Metabolic Bone Diseases Leuven BelgiumJ. Gaytant, Katholieke Universiteit Leuven Department of Andrology and Endocrinology Leuven Be... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3098630 Tue, 15 Dec 2009 06:44:50 +0100 3098630 Educational achievement and fracture risk: response to Clark and Tobias http://www.medworm.com/index.php?rid=3087353&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm56162r3h28467gv%2F Content Type Journal ArticleCategory LetterDOI 10.1007/s00198-009-1112-xAuthors S. L. Brennan, Monash University Department of Epidemiology and Preventive Medicine Melbourne AustraliaJ. A. Pasco, The University of Melbourne Department of Clinical and Biomedical Sciences: Barwon Health Geelong AustraliaD. M. Urquhart, Monash University Department of Epidemiology and Preventive Medicine Melbourne AustraliaB. Oldenburg, Monash University Department of Epidemiology and Preventive Medicine Melbourne AustraliaF. Hanna, Monash University Department of Epidemiology and Preventive Medicine Melbourne AustraliaA. E. Wluka, Monash University Department of Epidemiology and Preventive Medicine Melbourne Australia Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Sou... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3087353 Thu, 10 Dec 2009 15:14:14 +0100 3087353 Fibroblast growth factor-23 is associated with C-reactive protein, serum phosphate and bone mineral density in chronic kidney disease http://www.medworm.com/index.php?rid=3087355&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl7k62047j4241561%2F Conclusions  The data suggest that FGF-23 may be associated with parameters implicated in the complications of CKD. Longitudinal studies are required for further clinical evaluation. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1142-4Authors P. Manghat, 5th Floor, North Wing, St Thomas’ Hospital Department of Chemical Pathology Lambeth Palace Road London SE1 7EH UKW. D. Fraser, Royal Liverpool Hospital Department of Clinical Chemistry Liverpool UKA. S. Wierzbicki, 5th Floor, North Wing, St Thomas’ Hospital Department of Chemical Pathology Lambeth Palace Road London SE1 7EH UKI. Fogelman, Guy’s Hospital Department of Nuclear Medicine London UKD. J. Goldsmith, Guy’s Hospital Renal Unit London UKG. Hampson, 5th Floor, North Wing, St T... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3087355 Thu, 10 Dec 2009 15:14:12 +0100 3087355 Educational achievement and fracture risk http://www.medworm.com/index.php?rid=3087354&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fchk724830022k3l8%2F Content Type Journal ArticleCategory LetterDOI 10.1007/s00198-009-1115-7Authors E. Clark, University of Bristol Academic Rheumatology Bristol UKJ. Tobias, University of Bristol Academic Rheumatology Bristol UK Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3087354 Thu, 10 Dec 2009 15:14:12 +0100 3087354 Pedometer determined ambulatory activity and bone mass: a population-based longitudinal study in older adults http://www.medworm.com/index.php?rid=3087356&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F175715743u027132%2F Conclusion  In conclusion, pedometer-determined ambulatory activity has consistent clinically important associations with hip aBMD in both sexes which appears most important in those over 65 years of age. The associations for spine aBMD were both weaker and inconsistent suggesting site specificity. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1137-1Authors S. Foley, University of Tasmania Menzies Research Institute Hobart Australia 7001S. Quinn, University of Tasmania Menzies Research Institute Hobart Australia 7001G. Jones, University of Tasmania Menzies Research Institute Hobart Australia 7001 Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3087356 Thu, 10 Dec 2009 00:12:19 +0100 3087356 Epidemiology of hip fracture in Tucuman, Argentina http://www.medworm.com/index.php?rid=3081330&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp7305784625g2xnh%2F Conclusions  These results showed that the incidence of hip fracture in female and male populations in SMT was similar to previous studies performed in the central area of the country. Further studies on the south area of Argentina should be conducted to complete the information on a large country extending from latitudes 22° to 55°S. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1135-3Authors A. Wittich, Hospital Centro de Salud Servicio de Endocrinología Tucumán ArgentinaA. Bagur, Universidad de Buenos Aires Sección Osteopatías Médicas, Hospital de Clínicas Córdoba 2351 8° piso 1120 Buenos Aires ArgentinaC. Mautalen, Universidad de Buenos Aires Sección Osteopatías Médicas, Hospital de Clínicas Córdoba 2351 8° piso 1120 Bu... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3081330 Tue, 08 Dec 2009 19:47:02 +0100 3081330 A single dose of zoledronic acid reverses the deleterious effects of glucocorticoids on titanium implant osseointegration http://www.medworm.com/index.php?rid=3081332&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F6h2v372143743128%2F Conclusions  Our findings demonstrated that a single dose of ZOL is able to reverse the detrimental effects of glucocorticoids on the osseointegration of titanium implants, suggesting that ZOL therapy may improve the outcome of bone implants in patients with glucocorticoid-induced osteoporosis. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1125-5Authors J. S. B. Carvas, Faculdade de Medicina da Universidade de São Paulo Rheumatology Division Av. Dr. Arnaldo, 455, 3º andar, Reumatologia São Paulo SP 0124-6903 BrazilR. M. R. Pereira, Faculdade de Medicina da Universidade de São Paulo Rheumatology Division Av. Dr. Arnaldo, 455, 3º andar, Reumatologia São Paulo SP 0124-6903 BrazilV. F. Caparbo, Faculdade de Medicina da Universidade de S... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3081332 Tue, 08 Dec 2009 19:47:01 +0100 3081332 Use of oral bisphosphonates and risk of venous thromboembolism: a population-based case-control study http://www.medworm.com/index.php?rid=3081331&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F6722h801706768r7%2F Conclusion  We found no evidence of an association of oral bisphosphonate use with the risk of VTE. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1143-3Authors A. L. Lamberg, Aarhus University Hospital Department of Clinical Epidemiology Olof Palmes Allé 43-45 8200 Aarhus N DenmarkE. Horvath-Puho, Aarhus University Hospital Department of Clinical Epidemiology Olof Palmes Allé 43-45 8200 Aarhus N DenmarkS. Christensen, Aarhus University Hospital Department of Clinical Epidemiology Olof Palmes Allé 43-45 8200 Aarhus N DenmarkH. T. Sørensen, Aarhus University Hospital Department of Clinical Epidemiology Olof Palmes Allé 43-45 8200 Aarhus N Denmark Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: O... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3081331 Tue, 08 Dec 2009 19:47:01 +0100 3081331 Poor bisphosphonate adherence for treatment of osteoporosis increases fracture risk: systematic review and meta-analysis http://www.medworm.com/index.php?rid=3065297&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe73g3x5703w84814%2F Conclusions  Persistence and compliance are suboptimal for postmenopausal women undergoing bisphosphonate therapy for osteoporosis. The clinical consequence of this low compliance is an increased risk of fracture, which is lower for non-vertebral than for clinical vertebral fractures. Content Type Journal ArticleCategory Short CommunicationDOI 10.1007/s00198-009-1134-4Authors I. Imaz, Instituto de Salud Carlos III. Science and Innovation Ministry Agency for Health Technologies Assessment 5 Monforte de Lemos Madrid 28029 SpainP. Zegarra, Instituto de Salud Carlos III. Science and Innovation Ministry National School of Health Care 6 Sinesio Delgado Madrid 28209 SpainJ. González-Enríquez, Instituto de Salud Carlos III. Science and Innovation Ministry Agency for Health T... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3065297 Fri, 04 Dec 2009 21:12:40 +0100 3065297 Association of medication attitudes with non-persistence and non-compliance with medication to prevent fractures http://www.medworm.com/index.php?rid=3081333&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fvk517k897203g67w%2F Conclusions  Non-persistence and non-compliance with oral bisphosphonate medication have different, albeit overlapping, sets of predictors. Low perceived necessity of fracture-prevention medication, high concerns about long-term safety of and dependence upon medication , and low medication-use self-efficacy all predict non-persistence with oral bisphosphonates, whereas low medication-use self-efficacy strongly predicts non-compliance with oral bisphosphonate medication. Assessment of and influence of these medication attitudes among patients at high risk of fracture are likely necessary to achieve better persistence and compliance with fracture-prevention therapies. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1141-5Authors J. T. Schou... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3081333 Fri, 04 Dec 2009 21:12:32 +0100 3081333 The efficacy of calcitriol therapy in the management of bone loss and fractures: a qualitative review http://www.medworm.com/index.php?rid=3065298&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F14464w0882j38070%2F Abstract Summary  Osteoporosis, a skeletal disorder characterized by a reduction in bone strength, increases fracture risk. Primary osteoporosis is usually a result of reduced bone mineral density as a consequence of natural aging. Secondary osteoporosis is usually a result of a disease, such as cystic fibrosis, or medical treatment, such as corticosteroids or cancer treatment. Introduction  Currently, ten million Americans are osteoporotic and an additional 34 million have the precursor condition, osteopenia. Osteoporosis leads to 1.5 million fractures and 500,000 hospitalizations annually. Osteoporosis-related fractures increase mortality and reduce quality of life. Calcitriol, the active form of vitamin D, regulates intestinal calcium absorption, among ot... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3065298 Thu, 03 Dec 2009 18:20:07 +0100 3065298 Benefit–risk assessment of vitamin D supplementation http://www.medworm.com/index.php?rid=3065299&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg18x734546417446%2F Conclusion  Our analysis suggests that mean serum 25(OH)D levels of about 75 to 110 nmol/l provide optimal benefits for all investigated endpoints without increasing health risks. These levels can be best obtained with oral doses in the range of 1,800 to 4,000 IU vitamin D per day; further work is needed, including subject and environment factors, to better define the doses that will achieve optimal blood levels in the large majority of the population. Content Type Journal ArticleCategory ReviewDOI 10.1007/s00198-009-1119-3Authors H. A. Bischoff-Ferrari, University Hospital Zurich Centre on Aging and Mobility, Department of Rheumatology and Institute of Physical Medicine Gloriastrasse 25 8091 Zurich SwitzerlandA. Shao, Council for Responsible Nutrition Washi... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3065299 Wed, 02 Dec 2009 18:42:44 +0100 3065299 Anemia and the risk of non-vertebral fractures: the Tromsø Study http://www.medworm.com/index.php?rid=3065301&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff40h3806k6563831%2F Conclusion  Anemia is associated with non-vertebral fractures in men but not in women. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1131-7Authors L. Jørgensen, University of Tromsø Institute of Community Medicine 9037 Tromsø NorwayT. Skjelbakken, University Hospital of North Norway Division of Internal Medicine Tromsø NorwayM.-L. Løchen, University of Tromsø Institute of Community Medicine 9037 Tromsø NorwayL. Ahmed, University of Tromsø Institute of Community Medicine 9037 Tromsø NorwayÅ. Bjørnerem, University of Tromsø Institute of Community Medicine 9037 Tromsø NorwayR. Joakimsen, University of Tromsø Institute of Clinical Medicine Tromsø NorwayB. K. Jacobsen, University of Tromsø Institute of Community Medicine 9037 Trom... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3065301 Wed, 02 Dec 2009 18:42:42 +0100 3065301 Systemic treatment with strontium ranelate promotes tibial fracture healing in ovariectomized rats http://www.medworm.com/index.php?rid=3065300&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy14675087m53815l%2F Conclusion  This study suggests that systemic treatment with strontium ranelate could promote tibial fracture healing in OVX rats. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1140-6Authors Y. F. Li, Sichuan University The State Key Laboratory of Oral Diseases and Department of Oral and Maxillofacial Surgery, West China College of Stomatology NO. 14, Section 3, Southern Renmin Road Chendgu 610041 ChinaE. Luo, Sichuan University The State Key Laboratory of Oral Diseases and Department of Oral and Maxillofacial Surgery, West China College of Stomatology NO. 14, Section 3, Southern Renmin Road Chendgu 610041 ChinaG. Feng, Sichuan University The State Key Laboratory of Oral Diseases and Department of Oral and Maxillofacial Surgery, West China... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3065300 Wed, 02 Dec 2009 18:42:42 +0100 3065300 Alendronate reduces osteoclast precursors in osteoporosis http://www.medworm.com/index.php?rid=3054726&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F454n457407454265%2F Conclusions  We suggest that alendronate mainly acts on mature bone resorbing osteoclasts in the short term, whereas, its long-term administration diminishes their formation by reducing their precursors and serum RANKL. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1129-1Authors P. D’Amelio, University of Torino Gerontology Section, Department of Surgical and Medical Disciplines Corso Bramante 88/90 10126 Torino ItalyA. Grimaldi, University of Torino Gerontology Section, Department of Surgical and Medical Disciplines Corso Bramante 88/90 10126 Torino ItalyM. A. Cristofaro, University of Torino Gerontology Section, Department of Surgical and Medical Disciplines Corso Bramante 88/90 10126 Torino ItalyM. Ravazzoli, University of Torino Geron... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3054726 Tue, 01 Dec 2009 08:33:26 +0100 3054726 Fracture, bone mineral density, and the effects of calcitonin receptor gene in postmenopausal Koreans http://www.medworm.com/index.php?rid=3042225&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F1x7v650567118075%2F Conclusion  These results indicate that the CALCR gene may regulate bone metabolism, and +60644C > T in the CALCR gene may genetically modulate bone phenotype. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1106-8Authors H.-J. Lee, National Institute of Health The Center for Genome Science 5 Nokbun-dong, Eunpyung-gu Seoul 122-701 Republic of KoreaS.-Y. Kim, Kyungpook National University Hospital Skeletal Diseases Genome Research Center 44-2, Samduk 2-ga Jung-gu Daegu 700-412 Republic of KoreaG. S. Kim, Kyungpook National University Hospital Skeletal Diseases Genome Research Center 44-2, Samduk 2-ga Jung-gu Daegu 700-412 Republic of KoreaJ.-Y. Hwang, National Institute of Health The Center for Genome Science 5 Nokbun-dong, Eunpyung-gu S... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3042225 Sat, 28 Nov 2009 07:02:45 +0100 3042225 Application of the National Osteoporosis Foundation Guidelines to postmenopausal women and men: the Framingham Osteoporosis Study http://www.medworm.com/index.php?rid=3042226&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp375257kp7277030%2F Conclusions  Nearly one half of Caucasian postmenopausal women and one sixth of men aged 50 years and older would be recommended for osteoporosis treatment according to 2008 NOF Guidelines. Given the high proportion of persons recommended for treatment, NOF Guidelines may need to be re-evaluated with respect to budget impact. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1127-3Authors S. D. Berry, Hebrew SeniorLife Institute for Aging Research 1200 Centre Street Boston MA 02131 USAD. P. Kiel, Hebrew SeniorLife Institute for Aging Research 1200 Centre Street Boston MA 02131 USAM. G. Donaldson, California Pacific Medical Center San Francisco Coordinating Center San Francisco CA USAS. R. Cummings, California Pacific Medical Center San Fr... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3042226 Wed, 25 Nov 2009 16:48:44 +0100 3042226 Vitamin K2 supplementation does not influence bone loss in early menopausal women: a randomised double-blind placebo-controlled trial http://www.medworm.com/index.php?rid=3042227&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff227685211041064%2F Conclusion  MK-7 taken as Natto over 1 year reduced serum levels of ucOC but did not influence bone loss rates in early menopausal women. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1126-4Authors N. Emaus, University of Tromsø Institute of Community Medicine Tromsø 9037 NorwayC. G. Gjesdal, Haukeland University Hospital Bergen 5021 NorwayB. Almås, Haukeland University Hospital Bergen 5021 NorwayM. Christensen, Haukeland University Hospital Bergen 5021 NorwayA. S. Grimsgaard, University Hospital of North Norway Tromsø 9037 NorwayG. K. R. Berntsen, University of Tromsø The National Research Centre in Complementary and Alternative Medicine (NAFKAM) Tromsø 9037 NorwayL. Salomonsen, University of Tromsø The National Research Centre ... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3042227 Wed, 25 Nov 2009 16:48:43 +0100 3042227 Impact of a primary care physician workshop on osteoporosis medical practices http://www.medworm.com/index.php?rid=3042228&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn7510183w76604m4%2F Conclusions  Attendance at a primary care physician workshop was associated with higher rates of osteoporosis medical practices for elderly women and high-risk men and women. However, osteoporosis detection and treatment remained sub-optimal, particularly in men. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1116-6Authors M.-C. Laliberté, University of Montreal Faculty of Pharmacy Montreal QC CanadaS. Perreault, University of Montreal Faculty of Pharmacy Montreal QC CanadaA. Dragomir, University of Montreal Faculty of Pharmacy Montreal QC CanadaJ. Goudreau, Centre de santé et de services sociaux de Laval Research Team in Primary Care, Hôpital Cité-de-la-Santé 1755 René-Laennec Blvd., Room D-S080 Laval QC H7M 3L9 CanadaI. Rodrigues, Un... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3042228 Wed, 25 Nov 2009 16:48:41 +0100 3042228 Urinary cadmium, osteopenia, and osteoporosis in the US population http://www.medworm.com/index.php?rid=3032434&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fmv5832757q245353%2F Conclusions  Cadmium exposure may be a potential risk factor for osteopenia and osteoporosis in the general US population. Content Type Journal ArticleCategory Short CommunicationDOI 10.1007/s00198-009-1111-yAuthors Q. Wu, Biostatistics, Mayo Clinic 13400 East Shea Blvd Scottsdale AZ 85259 USAJ. H. Magnus, Tulane University School of Public Health and Tropical Medicine Department of Community Health Sciences New Orleans LA USAJ. G. Hentz, Biostatistics, Mayo Clinic 13400 East Shea Blvd Scottsdale AZ 85259 USA Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3032434 Tue, 24 Nov 2009 07:16:58 +0100 3032434 Cost-effectiveness of multifaceted evidence implementation programs for the prevention of glucocorticoid-induced osteoporosis http://www.medworm.com/index.php?rid=3032436&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc47j74583662j141%2F Conclusions  Evidence implementation programs for the management of GIOP are likely to be cost-effective to third-party health insurers only if they are targeted at individuals with a very high risk of fracture and the proportion of prescriptions for less expensive generic bisphosphonates increases substantially. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1114-8Authors T. Beukelman, University of Alabama at Birmingham Deep South Musculoskeletal Center for Education and Research on Therapeutics Birmingham AL USAK. G. Saag, University of Alabama at Birmingham Deep South Musculoskeletal Center for Education and Research on Therapeutics Birmingham AL USAJ. R. Curtis, University of Alabama at Birmingham Deep South Musculoskeletal Center for ... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3032436 Tue, 24 Nov 2009 07:16:57 +0100 3032436 A paediatric bone index derived by automated radiogrammetry http://www.medworm.com/index.php?rid=3032435&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl2l1552101316u22%2F Conclusions  As part of the BoneXpert method for automated bone age determination, our method facilitates retrospective research studies involving validation of the proposed index against fracture incidence and adult bone mineral density. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1085-9Authors H. H. Thodberg, Visiana Søllerødvej 57 C 2840 Holte DenmarkR. R. van Rijn, Emma Children’s Hospital/Academic Medical Centre Department of Radiology Amsterdam NetherlandsT. Tanaka, National Center for Child Health and Development Tokyo JapanD. D. Martin, University of Tübingen Tübingen GermanyS. Kreiborg, University of Copenhagen Copenhagen Denmark Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Ost... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3032435 Tue, 24 Nov 2009 07:16:57 +0100 3032435 Flare-up of hand osteoarthritis caused by zoledronic acid infusion http://www.medworm.com/index.php?rid=3021189&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fgw21j4519u46w884%2F We reported the case of a 64-year-old woman who presented flare-up of hand osteoarthritis after zoledronic acid infusions. Despite the fact that arthralgia is a common side effect of intravenous bisphosphonates, development of inflammatory signs in osteoarthritic joints is a rare event. We hypothesized that this side effect is caused by a release of cytokines secondary to activation of gamma-delta T lymphocytes. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s00198-009-1123-7Authors G. R. Werner de Castro, Hospital Governador Celso Ramos Rheumatology Unit Florianópolis BrazilF. S. Neves, Hospital Governador Celso Ramos Rheumatology Unit Florianópolis BrazilS. C. de Magalhães Souza Fialho, Universidade Federal de Santa Catarina Rheumatology Unit, Universitary Hospita... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3021189 Sat, 21 Nov 2009 08:29:29 +0100 3021189 The prevalence of radiographic vertebral fractures in Mexican men http://www.medworm.com/index.php?rid=3021188&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fql05h0072g738629%2F Abstract Summary  The prevalence of radiographically ascertained vertebral fractures in a random sample of 413 in Mexican men is 9.7% (95% CI 6.85–12.55). Increase of vertebral fracture rises with age from 2.0% in the youngest group (50–59 years) to 21.4% in the oldest group (80 years and over). Introduction  This is the first population-based study of vertebral fractures in Mexican men using a standardized methodology reported in other studies. Methods  The presence of radiographic vertebral fractures increases with age. This same pattern was found in Mexican women with steady age increments, but the higher prevalence of fractures in women starts at age 70, whereas in men, the higher prevalence starts a decade later (80 ... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3021188 Sat, 21 Nov 2009 08:29:29 +0100 3021188 Maternal high-fat diet: effects on offspring bone structure http://www.medworm.com/index.php?rid=3021191&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp0jk522687764012%2F Conclusions  A maternal HF diet during pregnancy increases bone marrow adiposity and alters bone structure in their offspring. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1118-4Authors S. A. Lanham, University of Southampton School of Medicine Bone and Joint Research Group, Developmental Origins of Health and Disease Division, Institute of Developmental Sciences Southampton SO16 6YD UKC. Roberts, University of Southampton School of Medicine Bone and Joint Research Group, Developmental Origins of Health and Disease Division, Institute of Developmental Sciences Southampton SO16 6YD UKT. Hollingworth, University of Southampton School of Medicine Bone and Joint Research Group, Developmental Origins of Health and Disease Division, Institute of ... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3021191 Sat, 21 Nov 2009 08:29:27 +0100 3021191 Bone loss and the risk of non-vertebral fractures in women and men: the Tromsø study http://www.medworm.com/index.php?rid=3021190&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy07l567221142308%2F Conclusion  Bone loss at the distal forearm predicted non-vertebral fractures, independently of baseline BMD, but not independently of follow-up BMD, in women. The BMD level where an individual ends up is the significant predictor of fracture risk and not the rate of bone loss. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1102-zAuthors L. A. Ahmed, University of Tromsø Institute of community medicine 9037 Tromsø NorwayN. Emaus, University of Tromsø Institute of community medicine 9037 Tromsø NorwayG. K. Berntsen, University Hospital of North Norway NST Tromsø NorwayÅ. Bjørnerem, University of Tromsø Institute of community medicine 9037 Tromsø NorwayV. Fønnebø, University of Tromsø Institute of community medicine 9037 Tromsø N... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3021190 Sat, 21 Nov 2009 08:29:27 +0100 3021190 The association between osteoporosis and static balance in elderly women http://www.medworm.com/index.php?rid=3021192&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F798h801276k843m5%2F Conclusion  The results suggest that osteoporotic women had the worst balance, possibly due to the more pronounced body changes compared to non-osteoporotic women. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1117-5Authors D. C. Abreu, University of São Paulo, School of Medicine, Ribeirão Preto FMRP-USP Physiotherapy Course, Department of Biomechanics, Medicine and Rehabilitation of Locomotor System Ribeirão Preto SP BrazilD. C. Trevisan, University of São Paulo, School of Medicine, Ribeirão Preto FMRP-USP Physiotherapy Course, Department of Biomechanics, Medicine and Rehabilitation of Locomotor System Ribeirão Preto SP BrazilG. C. Costa, University of São Paulo, School of Medicine, Ribeirão Preto FMRP-USP Physiotherapy Course, Dep... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3021192 Sat, 21 Nov 2009 08:29:23 +0100 3021192 Low bone mineral density is not associated with angiographically determined coronary atherosclerosis in men http://www.medworm.com/index.php?rid=3021193&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe325615350036062%2F Conclusions  The prevalence of low BMD is very high in men undergoing coronary angiography. However, low BMD is not associated with angiographically determined coronary atherosclerosis in men. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1103-yAuthors S. Beer, Vorarlberg Institute for Vascular Investigation and Treatment (VIVIT) Feldkirch AustriaC. H. Saely, Vorarlberg Institute for Vascular Investigation and Treatment (VIVIT) Feldkirch AustriaG. Hoefle, Vorarlberg Institute for Vascular Investigation and Treatment (VIVIT) Feldkirch AustriaP. Rein, Vorarlberg Institute for Vascular Investigation and Treatment (VIVIT) Feldkirch AustriaA. Vonbank, Vorarlberg Institute for Vascular Investigation and Treatment (VIVIT) Feldkirch AustriaJ. Breus... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3021193 Sat, 21 Nov 2009 08:29:22 +0100 3021193 Cost-effectiveness of balloon kyphoplasty in patients with symptomatic vertebral compression fractures in a UK setting http://www.medworm.com/index.php?rid=3016439&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn64x66x327k41537%2F Conclusion  In conclusion, the results indicate that BKP provides a cost-effective alternative for treating patients with hospitalised VCFs in a UK-setting. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1096-6Authors O. Ström, i3 Innovus Stockholm SwedenC. Leonard, Medtronic Ltd Watford UKD. Marsh, Royal National Orthopaedic Hospital Stanmore UKC. Cooper, University of Southampton MRC Epidemiology Resource Centre Southampton UK Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3016439 Thu, 19 Nov 2009 07:39:21 +0100 3016439 Cost of falls in old age: a systematic review http://www.medworm.com/index.php?rid=3016438&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn1k7310277x64740%2F Conclusion  Falls are a relevant economic burden to society. Efforts should be directed to economic evaluations of fall-prevention programmes aiming at reducing fall-related fractures, which contribute substantially to fall-related costs. Content Type Journal ArticleCategory ReviewDOI 10.1007/s00198-009-1100-1Authors S. Heinrich, University of Leipzig Health Economics Research Unit, Department of Psychiatry Liebigstraße 26 04103 Leipzig GermanyK. Rapp, Robert-Bosch-Hospital Department of Clinical Gerontology Stuttgart GermanyU. Rissmann, Robert-Bosch-Hospital Department of Clinical Gerontology Stuttgart GermanyC. Becker, Robert-Bosch-Hospital Department of Clinical Gerontology Stuttgart GermanyH.-H. König, University of Leipzig Health Economics Research Unit, Departme... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3016438 Thu, 19 Nov 2009 07:39:21 +0100 3016438 Prevalent vertebral deformity independently increases incident vertebral fracture risk in middle-aged and elderly Japanese women: The Japanese Population-based Osteoporosis (JPOS) Cohort Study http://www.medworm.com/index.php?rid=3016437&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F75n854864j5756r1%2F Conclusion  Vertebral deformity was associated with a 3-fold increase in subsequent vertebral fracture risk in Japanese women, and this association was stronger in middle-aged women. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1113-9Authors E. Kadowaki, Kinki University School of Medicine Department of Public Health 377-2 Oono-higashi Osaka-Sayama 589-8511 JapanJ. Tamaki, Kinki University School of Medicine Department of Public Health 377-2 Oono-higashi Osaka-Sayama 589-8511 JapanM. Iki, Kinki University School of Medicine Department of Public Health 377-2 Oono-higashi Osaka-Sayama 589-8511 JapanY. Sato, Jin-ai University Department of Human Life Echizen JapanY. Chiba, Kinki University School of Medicine Department of Environmental Medici... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3016437 Thu, 19 Nov 2009 07:39:21 +0100 3016437 Urinary deoxypyridinoline is a BMD-independent marker for prevalent vertebral fractures in postmenopausal women treated with glucocorticoid http://www.medworm.com/index.php?rid=3016440&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc182474g5121108p%2F Conclusion  Urinary DPD level was significantly associated with prevalent vertebral fractures in GC-treated postmenopausal women independently of lumbar spine BMD. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1108-6Authors H. Kaji, Kobe University Graduate School of Medicine Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine 7-5-2 Kusunoki-cho, Chuo-ku Kobe 650-0017 JapanM. Yamauchi, Shimane University Faculty of Medicine Internal Medicine 1 Matsue Shimane JapanT. Yamaguchi, Shimane University Faculty of Medicine Internal Medicine 1 Matsue Shimane JapanT. Sugimoto, Shimane University Faculty of Medicine Internal Medicine 1 Matsue Shimane Japan Journal Osteoporosis InternationalOnline ISSN 1433-2965Pr... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3016440 Wed, 18 Nov 2009 19:17:59 +0100 3016440 Treatment of osteoporosis: recognizing and managing cutaneous adverse reactions and drug-induced hypersensitivity http://www.medworm.com/index.php?rid=3010675&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy02t87776r361174%2F Conclusion  With early recognition and proper management, including immediate and permanent withdrawal of the culprit agent, accompanied by hospitalization and rehydration and systemic corticosteroids if necessary, the prognosis is good. Content Type Journal ArticleCategory ReviewDOI 10.1007/s00198-009-1097-5Authors P. Musette, Charles Nicolle University Hospital Department of Dermatology and INSERM Unit 905 Rouen FranceM. L. Brandi, University of Florence Department of Internal Medicine Florence ItalyP. Cacoub, AH-HP, Hôpital Pitié Salpétrière, and Université Pierre et Marie Curie Department of Internal Medicine Paris 6 Paris FranceJ. M. Kaufman, UZ Gent Department of Internal Medicine Ghent BelgiumR. Rizzoli, Geneva University Hospitals Geneva SwitzerlandJ.-Y. Re... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3010675 Tue, 17 Nov 2009 23:47:01 +0100 3010675 Effect of alendronate on bone metabolic indices and bone mineral density in patients treated with high-dose glucocorticoid: a prospective study http://www.medworm.com/index.php?rid=3010674&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F0254425831385685%2F Conclusion  Alendronate was effective in suppressing bone resorption and subsequent BMD decrease at the lumbar spine in patients with high-dose GC treatment. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1110-zAuthors H. Kaji, Kobe University Graduate School of Medicine Division of Diabetes, Metabolism and Endocrinology, Department of Internal Medicine 7-5-2 Kusunoki-cho, Chuo-ku Kobe 650-0017 JapanY. Kuroki, Kobe Century Memorial Hospital Internal Medicine Kobe JapanY. Murakawa, Shimane University Faculty of Medicine Internal Medicine 3 Izumo JapanI. Funakawa, National Hyogo-Chuo Hospital Sanda JapanY. Funasaka, Kobe University Graduate School of Medicine Division of Dermatology 7-5-2 Kusunoki-cho, Chuo-ku Kobe 650-0017 JapanF. Kanda, Kobe... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3010674 Tue, 17 Nov 2009 23:47:01 +0100 3010674 Measurement uncertainty for the analysis of serum 25-hydroxyvitamin D http://www.medworm.com/index.php?rid=3010673&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F886g8558282h5w0k%2F Content Type Journal ArticleCategory Letter to the EditorDOI 10.1007/s00198-009-1099-3Authors H. C. M. Stepman, Ghent University Laboratory for Analytical Chemistry, Faculty of Pharmaceutical Sciences Harelbekestraat 72 9000 Ghent BelgiumL. M. Thienpont, Ghent University Laboratory for Analytical Chemistry, Faculty of Pharmaceutical Sciences Harelbekestraat 72 9000 Ghent Belgium Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3010673 Tue, 17 Nov 2009 23:47:01 +0100 3010673 Measurement uncertainty for the analysis of serum 25-hydroxyvitamin D: response to Stepman and Thienpont http://www.medworm.com/index.php?rid=3010677&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fxj44315gh7137437%2F Content Type Journal ArticleCategory Letter to the EditorDOI 10.1007/s00198-009-1098-4Authors E. Cavalier, University Hospital of Liège Department of Clinical Chemistry, University of Liège Domaine du Sart-Tilman 4000 Liège BelgiumP. Delanaye, University Hospital of Liège Department of Nephrology, Dialysis and Hypertension, University of Liège Liège BelgiumC. Cormier, Hôpital Cochin Department of Rheumatology Paris FranceJ. C. Souberbielle, Hôpital Necker-Enfants Malades Laboratoire d’Explorations Fonctionnelles Paris France Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3010677 Tue, 17 Nov 2009 23:46:59 +0100 3010677 Cross-sectional geometry of weight-bearing tibia in female athletes subjected to different exercise loadings http://www.medworm.com/index.php?rid=3010676&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ffj232v6v321g76u3%2F Conclusions  High-impact, odd-impact, and repetitive low-impact exercise loadings were associated with thicker cortex at the distal tibia. At the tibial shaft, impact loading was not only associated with thicker cortex, but also a larger cross-sectional area. High-magnitude exercise loading did not show such associations at either site but was comparable to repetitive non-impact loading and reference data. Collectively, the relevance of high strain rate together with moderate-to-high strain magnitude as major determinants of osteogenic loading of the weight-bearing tibia is implicated. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1101-0Authors R. Nikander, UKK Institute for Health Promotion Research Bone Research Group Kaupinpuistonkatu... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=3010676 Tue, 17 Nov 2009 23:46:59 +0100 3010676 Compromised bone strength index in the hemiparetic distal tibia epiphysis among chronic stroke patients: the association with cardiovascular function, muscle atrophy, mobility, and spasticity http://www.medworm.com/index.php?rid=2952931&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fpnr41798g181kk23%2F Conclusions  Cardiovascular function, muscle atrophy, mobility, and spasticity are independently associated with BSI of the distal tibia epiphysis among chronic stroke patients. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1038-3Authors M. Y. C. Pang, Hong Kong Polytechnic University Department of Rehabilitation Sciences Hung Hom Hong Kong ChinaM. C. Ashe, University of British Columbia Department of Physical Therapy Vancouver BC CanadaJ. J. Eng, University of British Columbia Department of Physical Therapy Vancouver BC Canada Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2952931 Fri, 30 Oct 2009 18:15:13 +0100 2952931 Immune changes in post-menopausal osteoporosis: the Immunos study http://www.medworm.com/index.php?rid=2948024&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2168664l72214298%2F Conclusions  Our results suggest that, regardless of age and estrogen status, postmenopausal OP is associated with immune changes, highlighting a possible role of IFN-γ in the pathophysiology of OP and reporting, for the first time, changes in several B lymphocyte populations. These alterations may reflect the frailty observed after fracture, providing new insight into the mechanisms of morbidity and mortality associated with OP fractures. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1018-7Authors V. Breuil, CHU de Nice, Hôpital l’Archet Service de Rhumatologie Route Saint Antoine de Ginestière 06200 Nice FranceM. Ticchioni, CHU Nice, Hôpital l’Archet Laboratoire d’Immunologie Nice FranceJ. Testa, CHU de Nice Département d’I... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2948024 Fri, 30 Oct 2009 07:53:27 +0100 2948024 Osteonecrosis of the jaw in patients receiving oral bisphosphonates http://www.medworm.com/index.php?rid=2941602&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh204425p612520m8%2F Content Type Journal ArticleCategory LetterDOI 10.1007/s00198-009-1089-5Authors Athanassios Kyrgidis, Theagenio Cancer Hospital Department of Oral and Maxillofacial Surgery Thessaloniki GreeceKonstantinos Vahtsevanos, Theagenio Cancer Hospital Department of Oral and Maxillofacial Surgery Thessaloniki Greece Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2941602 Wed, 28 Oct 2009 06:58:24 +0100 2941602 Alveolar bone density measurement in risk assessment for bisphosphonate-related osteonecrosis of the jaw: response to comments by Taguchi http://www.medworm.com/index.php?rid=2936916&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj62r8254176711x1%2F Content Type Journal ArticleCategory LetterDOI 10.1007/s00198-009-1093-9Authors Y. Takaishi, Takaishi Dental Clinic 3-32, Hojo-guchi Himeji 670-0935 JapanT. Ikeo, Osaka Dental University Department of Biochemistry Osaka JapanM. Nakajima, Osaka Dental University Department of Oral and Maxillofacial Surgery Osaka JapanT. Miki, Osaka City University Department of Geriatric Medicine Osaka JapanT. Fujita, Katsuragi Hospital Osaka Japan Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2936916 Mon, 26 Oct 2009 17:45:22 +0100 2936916 Automated 3D trabecular bone structure analysis of the proximal femur—prediction of biomechanical strength by CT and DXA http://www.medworm.com/index.php?rid=2936918&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F9m3881l017u91810%2F Conclusion  A combination of bone mass (DXA) and structure parameters of the trabecular bone (linear and nonlinear, global and local) most accurately predicted absolute and relative femoral bone strength. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1090-zAuthors T. Baum, Technische Universität München Institut für Röntgendiagnostik, Klinikum Rechts der Isar Ismaninger Str. 22 81675 Munich GermanyJ. Carballido-Gamio, University of California, San Francisco Musculoskeletal and Quantitative Imaging Research, Department of Radiology 185 Berry Street, Suite 350 San Francisco CA 94107 USAM. B. Huber, University of California, San Francisco Musculoskeletal and Quantitative Imaging Research, Department of Radiology 185 Berry Street, Suite 350... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2936918 Mon, 26 Oct 2009 17:45:18 +0100 2936918 Does standardized BMD still remove differences between Hologic and GE-Lunar state-of-the-art DXA systems? http://www.medworm.com/index.php?rid=2936917&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh302547k441444n1%2F Conclusions  The sBMD values were shown to be equivalent within 1.0% for hip but were significantly different for spine on the two systems. Biases may persist in pooled sBMD data from different manufacturers, and further study is necessary to determine the cause. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1062-3Authors B. Fan, University of California San Francisco Department of Radiology and Biomedical Imaging San Francisco CA USAY. Lu, University of California San Francisco Department of Radiology and Biomedical Imaging San Francisco CA USAH. Genant, University of California San Francisco Department of Radiology and Biomedical Imaging San Francisco CA USAT. Fuerst, Synarc, Inc San Francisco CA USAJ. Shepherd, University of California S... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2936917 Mon, 26 Oct 2009 17:45:18 +0100 2936917 Orbital inflammatory disease secondary to a single-dose administration of zoledronic acid for treatment of postmenopausal osteoporosis http://www.medworm.com/index.php?rid=2936919&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F183mp0kj01117418%2F Abstract  A 60-year-old woman received a single 5-mg dose of zoledronic acid (Aclasta®) for treatment of postmenopausal osteoporosis. One day after receiving the drug, she acutely developed a painful periorbital swelling, chemosis, and hyperemia in the right eye. The condition worsened despite initial treatment with topical steroids. An orbital CT scan showed right eye proptosis, eyelid edema, and intraorbital fat stranding. A diagnosis of orbital inflammatory disease was made, and the patient was treated with high-dose oral steroids (prednisone 80 mg/day) tapered along 6 weeks. The symptoms and the swelling reduced progressively after initiating oral prednisone, and after 12 days, there was complete resolution of the condition. The patient remained symptom ... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2936919 Mon, 26 Oct 2009 17:45:17 +0100 2936919 PTH improves titanium implant fixation more than pamidronate or renutrition in osteopenic rats chronically fed a low protein diet http://www.medworm.com/index.php?rid=2936920&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg333q4g378701h3v%2F Conclusions  PTH reversed the deleterious effects of long-term protein undernutrition on mechanical fixation and bone microarchitecture and improved implant osseointegration more than pamidronate or renutrition, likely through changes to structure model index. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1031-xAuthors R. Dayer, Geneva University Hospitals and Faculty of Medicine Division of Bone Diseases (WHO Collaborating Center for Osteoporosis Prevention), Department of Rehabilitation and Geriatrics 1211 Geneva 14 SwitzerlandT. C. Brennan, Geneva University Hospitals and Faculty of Medicine Division of Bone Diseases (WHO Collaborating Center for Osteoporosis Prevention), Department of Rehabilitation and Geriatrics 1211 Geneva 14 Switzer... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2936920 Mon, 26 Oct 2009 17:45:14 +0100 2936920 Burden of hip fracture on inpatient care: a before and after population-based study http://www.medworm.com/index.php?rid=2936921&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F0hhwp102407n1l43%2F Conclusions  Osteoporotic HF represents a pronounced excess expenditure in hospital, which is mostly linked to rehabilitation care. Considering that utilization of inpatient acute care was quite similar before and after the index stay, HF might result from a patient's pre-fracture poor health status, rather than predispose to a worsening of such pre-existing conditions. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1087-7Authors A. Duclos, Hospices Civils de Lyon Pôle Information Médicale Évaluation Recherche Lyon 69003 FranceS. Couray-Targe, Hospices Civils de Lyon Pôle Information Médicale Évaluation Recherche Lyon 69003 FranceM. Randrianasolo, Hospices Civils de Lyon Pôle Information Médicale Évaluation Recherche Lyon 69003 Fra... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2936921 Mon, 26 Oct 2009 17:45:12 +0100 2936921 Use of bisphosphonates and raloxifene and risk of deep venous thromboembolism and pulmonary embolism http://www.medworm.com/index.php?rid=2936923&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F77820h3041812132%2F Conclusion  Bisphosphonates seem associated with an increased risk of DVT/PE. However, the association does not seem to be causal. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1091-yAuthors P. Vestergaard, Aarhus University Hospital Department of Endocrinology and Metabolism C Tage Hansens Gade 2 8000 Arhus C DenmarkK. Schwartz, University of Copenhagen Department of Oral and Maxillofacial Surgery, Institute of Odontology, Faculty of Health Sciences Norre alle 20 2200 Copenhagen N DenmarkE. M. Pinholt, University of Copenhagen Department of Oral and Maxillofacial Surgery, Institute of Odontology, Faculty of Health Sciences Norre alle 20 2200 Copenhagen N DenmarkL. Rejnmark, Aarhus University Hospital Department of Endocrinology and Metaboli... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2936923 Mon, 26 Oct 2009 17:45:10 +0100 2936923 Alveolar density measurement and bisphosphonate-related osteonecrosis of the jaws http://www.medworm.com/index.php?rid=2936922&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff73r7t5738735022%2F Content Type Journal ArticleCategory LetterDOI 10.1007/s00198-009-1094-8Authors A. Taguchi, Matsumoto Dental University Department of Oral and Maxillofacial Radiology, School of Dentistry 1780 Gobara, Hirooka Shiojiri 399-0781 Japan Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2936922 Mon, 26 Oct 2009 17:45:10 +0100 2936922 Successful treatment of sternal fracture nonunion with teriparatide http://www.medworm.com/index.php?rid=2936924&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn44p5782l2921kxn%2F Conclusion  Based on the success of teriparatide in animal studies to accelerate fracture healing, there is growing interest in using this drug in humans for the same purpose. We report a case of what we believe to be the first successful use of teriparatide in the healing of a sternal nonunion fracture. Content Type Journal ArticleCategory Case ReportDOI 10.1007/s00198-009-1061-4Authors S. Chintamaneni, Stony Brook University Medical Center Rheumatology New York USAK. Finzel, Radiology, ProHealth Care Associates New York USAB. L. Gruber, NY College of Osteopathic Medicine (NYCOM) New York USA Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2936924 Mon, 26 Oct 2009 17:45:07 +0100 2936924 Daidzein administration positively affects thyroid C cells and bone structure in orchidectomized middle-aged rats http://www.medworm.com/index.php?rid=2936925&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F61817w2813236856%2F Conclusions  These findings indicate that daidzein treatment stimulates thyroid C cells, increase trabecular bone mass, and decrease bone turnover in Orx middle-aged rats, which is the model of male osteoporosis. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1092-xAuthors B. Filipović, Institute for Biological Research Belgrade SerbiaB. Šošić-Jurjević, Institute for Biological Research Belgrade SerbiaV. Ajdžanović, Institute for Biological Research Belgrade SerbiaD. Brkić, Johnson and Johnson S.E. Inc. Belgrade SerbiaM. Manojlović-Stojanoski, Institute for Biological Research Belgrade SerbiaV. Milošević, Institute for Biological Research Belgrade SerbiaM. Sekulić, Institute for Biological Research Belgrade Serbia Journal ... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2936925 Mon, 26 Oct 2009 17:45:03 +0100 2936925 Bone mineral density and fractures in older men with chronic obstructive pulmonary disease or asthma http://www.medworm.com/index.php?rid=2880742&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg28w37v274nl7u4w%2F Conclusion  Chronic obstructive pulmonary disease or asthma was associated with lower BMD at the spine and hip and increased risk of vertebral and nonvertebral fractures independent of age, clinic site, BMI, and smoking. A history of COPD or asthma may be a useful clinical risk factor to identify patients with osteoporosis. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1076-xAuthors T.-T. Dam, Columbia University Department of Medicine, College of Physicians and Surgeons New York New York USAS. Harrison, Research Institute, California Pacific Medical Center San Francisco California USAH. A. Fink, University of Minnesota Geriatric Research Education and Clinical Center and Center for Chronic Disease Outcomes Research, Veterans Affairs Medic... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2880742 Fri, 09 Oct 2009 06:15:43 +0100 2880742 Respiratory complications associated with IV zoledronic acid infusion in the treatment of postmenopausal osteoporosis http://www.medworm.com/index.php?rid=2878032&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fmt6847h1ut0704t0%2F Content Type Journal ArticleCategory LetterDOI 10.1007/s00198-009-1088-6Authors H. Taggart, Osteoporosis Clinic Belfast City Hospital Lisburn Road Belfast BT9 7AB UKJ. Cheng, Osteoporosis Clinic Belfast City Hospital Lisburn Road Belfast BT9 7AB UKP. Archbold, Osteoporosis Clinic Belfast City Hospital Lisburn Road Belfast BT9 7AB UK Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2878032 Thu, 08 Oct 2009 06:55:42 +0100 2878032 Relationship between 3-month changes in biochemical markers of bone remodelling and changes in bone mineral density and fracture incidence in patients treated with strontium ranelate for 3 years http://www.medworm.com/index.php?rid=2878035&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Flprw110221340757%2F Conclusions  Short-term changes in biochemical markers of bone formation are associated with future BMD changes in patients treated with strontium ranelate, suggesting a bone-forming activity of this treatment, but are not appropriate to monitor the efficacy of strontium ranelate at the individual level. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1078-8Authors O. Bruyère, University of Liège Department of Public Health, Epidemiology and Health Economics, CHU Sart-Tilman Bât B23 4000 Liège BelgiumJ. Collette, University of Liège Department of Public Health, Epidemiology and Health Economics, CHU Sart-Tilman Bât B23 4000 Liège BelgiumR. Rizzoli, Department of Rehabilitation and Geriatrics Geneve SwitzerlandC. Decock, University of ... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2878035 Thu, 08 Oct 2009 06:55:41 +0100 2878035 Low-energy distal radius fractures in middle-aged and elderly men and women—the burden of osteoporosis and fracture risk http://www.medworm.com/index.php?rid=2878034&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv2xg744211p22234%2F Conclusions  Every second to every third fracture patient met the present BMD criteria for osteoporosis treatment. Because a large proportion of distal radius fracture patients did not have osteoporosis, treatment decisions should not be based on fracture risk assessment without bone densitometry. Thus, all distal radius fracture patients ≥50 years should be referred to bone densitometry, and if indicated, offered medical treatment. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1068-xAuthors J. Øyen, University of Bergen Department of Surgical Sciences, Faculty of Medicine and Dentistry 5021 Bergen NorwayC. G. Gjesdal, Haukeland University Hospital Department of Rheumatology Bergen NorwayC. Brudvik, University of Bergen Department... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2878034 Thu, 08 Oct 2009 06:55:41 +0100 2878034 Suppressive effects of 1,4-dihydroxy-2-naphthoic acid administration on bone resorption http://www.medworm.com/index.php?rid=2878033&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F577m21k486751132%2F Conclusion  These results show that DHNA has some effects for improving bone mass reduction caused by FK506. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1075-yAuthors M. Matsubara, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Department of Oral and Maxillofacial Reconstructive Surgery 2-5-1 Sikata-cho Okayama City 7008525 JapanE. Yamachika, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Department of Oral and Maxillofacial Reconstructive Surgery 2-5-1 Sikata-cho Okayama City 7008525 JapanH. Tsujigiwa, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences Department of Virology 2-5-1 Sikata-cho Okayama City 7008525 JapanN. Mizukaw... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2878033 Thu, 08 Oct 2009 06:55:41 +0100 2878033 Detecting early bone changes using in vivo micro-CT in ovariectomized, zoledronic acid-treated, and sham-operated rats http://www.medworm.com/index.php?rid=2874129&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft6757536794t0294%2F Conclusions  Treatment with zoledronic acid as late as 2 weeks after ovariectomy still facilitates the full reversal of cancellous bone loss in the rat tibia. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1082-zAuthors E. Perilli, SA Pathology and Hanson Institute Bone and Joint Research Laboratory, Surgical Pathology Frome Road Adelaide 5000 AustraliaV. Le, SA Pathology and Hanson Institute Bone and Joint Research Laboratory, Surgical Pathology Frome Road Adelaide 5000 AustraliaB. Ma, SA Pathology and Hanson Institute Bone and Joint Research Laboratory, Surgical Pathology Frome Road Adelaide 5000 AustraliaP. Salmon, Skyscan NV Kontich BelgiumK. Reynolds, Flinders University School of Computer Science, Engineering & Mathematics Adelaid... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2874129 Wed, 07 Oct 2009 07:37:59 +0100 2874129 Hip fractures in Italy: 2000–2005 extension study http://www.medworm.com/index.php?rid=2874130&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa1l141678154p3t2%2F Conclusions  Hip fractures of the elderly are increasing and represent a major health problem in industrialized countries such as Italy. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1084-xAuthors P. Piscitelli, University of Florence Florence ItalyF. Gimigliano, Second University of Naples Naples ItalyS. Gatto, Second University of Naples Naples ItalyA. Marinelli, Second University of Naples Naples ItalyA. Gimigliano, Second University of Naples Naples ItalyP. Marinelli, Second University of Naples Naples ItalyG. Chitano, ISBEM Research Institute via Reali di Bulgaria 72023 Mesagne Brindisi ItalyM. Greco, ISBEM Research Institute via Reali di Bulgaria 72023 Mesagne Brindisi ItalyL. Di Paola, ISBEM Research Institute via Reali di Bulgaria 72... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2874130 Wed, 07 Oct 2009 07:37:58 +0100 2874130 Hip protectors: recommendations for biomechanical testing—an international consensus statement (part I) http://www.medworm.com/index.php?rid=2870531&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F45422p2p32w92326%2F Abstract Introduction  Hip protectors represent a promising strategy for preventing fall-related hip fractures. However, clinical trials have yielded conflicting results due, in part, to lack of agreement on techniques for measuring and optimizing the biomechanical performance of hip protectors as a prerequisite to clinical trials. Methods  In November 2007, the International Hip Protector Research Group met in Copenhagen to address barriers to the clinical effectiveness of hip protectors. This paper represents an evidence-based consensus statement from the group on recommended methods for evaluating the biomechanical performance of hip protectors. Results and conclusions  The primary outcome of testing should be the percent reduction (compa... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2870531 Tue, 06 Oct 2009 12:51:58 +0100 2870531 Osteoporosis and venous thromboembolism: a retrospective cohort study in the UK General Practice Research Database http://www.medworm.com/index.php?rid=2870530&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc72l383648v82320%2F Conclusion  This study shows a greater association of VTE in osteoporotic compared to non-osteoporotic patients, but does not show any greater association in treated patients with strontium ranelate or alendronate compared to untreated osteoporotic patients. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1050-7Authors G. Breart, Hôpital Tenon INSERM U 953 4 rue de la Chine 75020 Paris FranceC. Cooper, University of Southampton MRC Epidemiology Resource Centre Southampton UKO. Meyer, AP-HP Hôpital Bichat 46 rue Henri Huchard 75018 Paris FranceC. Speirs, Epsom Hospital John Kilner Diabetic Unit Dorking Road, Epsom Surrey KT18 7EG UKN. Deltour, Institut de Recherches Internationales Servier 92415 Courbevoie FranceJ. Y. Reginster, University o... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2870530 Tue, 06 Oct 2009 12:51:58 +0100 2870530 Hip protectors: recommendations for conducting clinical trials—an international consensus statement (part II) http://www.medworm.com/index.php?rid=2870529&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc545373415462875%2F Abstract Introduction  While hip protectors are effective in some clinical trials, many, including all in community settings, have been unable to demonstrate effectiveness. This is due partly to differences in the design and analysis. The aim of this report is to develop recommendations for subsequent clinical research. Methods  In November of 2007, the International Hip Protector Research Group met to address barriers to the clinical effectiveness of hip protectors. This paper represents a consensus statement from the group on recommended methods for conducting future clinical trials of hip protectors. Results and conclusions  Consensus recommendations include the following: the use of a hip protector that has undergone adequate biomechanic... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2870529 Tue, 06 Oct 2009 12:51:58 +0100 2870529 The effect of weight training on bone mineral density and bone turnover in postmenopausal breast cancer survivors with bone loss: a 24-month randomized controlled trial http://www.medworm.com/index.php?rid=2864310&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr548144264243821%2F Conclusion  Strength/weight training exercises may prevent loss of BMD in postmenopausal BCS at risk for bone loss. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1083-yAuthors N. L. Waltman, University of Nebraska Medical Center College of Nursing Lincoln Division 1230 “O” Street, Ste. 131 Lincoln NE 685880220 USAJ. J. Twiss, University of Nebraska Medical Center College of Nursing Omaha Division Omaha NE USAC. D. Ott, University of Nebraska Medical Center College of Nursing Kearney Division Kearney NE USAG. J. Gross, University of Nebraska Medical Center College of Nursing Omaha Division Omaha NE USAA. M. Lindsey, University of Nebraska Medical Center College of Nursing Omaha NE USAT. E. Moore, University of Nebraska College of Medicine... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2864310 Sat, 03 Oct 2009 06:32:54 +0100 2864310 The differences of femoral neck geometric parameters: effects of age, gender and race http://www.medworm.com/index.php?rid=2864311&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh458568644240187%2F Conclusion  In conclusion, the differences of FNGPs according to gender and ethnicity provide important implications in the different prevalence of osteoporotic fracture among different gender and ethnic groups. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1057-0Authors F. Zhang, Hunan Normal University Laboratory of Molecular and Statistical Genetics, College of Life Sciences Changsha Hunan 410081 People’s Republic of ChinaL.-J. Tan, Hunan Normal University Laboratory of Molecular and Statistical Genetics, College of Life Sciences Changsha Hunan 410081 People’s Republic of ChinaS.-F. Lei, Hunan Normal University Laboratory of Molecular and Statistical Genetics, College of Life Sciences Changsha Hunan 410081 People’s Republic of Chin... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2864311 Sat, 03 Oct 2009 06:32:53 +0100 2864311 Calcium supplement and bone loss http://www.medworm.com/index.php?rid=2864313&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg6u17074k22184l4%2F Content Type Journal ArticleCategory LetterDOI 10.1007/s00198-009-1073-0Authors T. V. Nguyen, Garvan Institute of Medical Research Osteoporosis and Bone Biology Program 384 Victoria Street Sydney New South Wales Australia Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2864313 Sat, 03 Oct 2009 06:32:51 +0100 2864313 Effect of once-yearly zoledronic acid on the spine and hip as measured by quantitative computed tomography: results of the HORIZON Pivotal Fracture Trial http://www.medworm.com/index.php?rid=2864312&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq2xl36v72t12x773%2F Conclusions  Once-yearly ZOL increased hip and spine BMD vs placebo, assessed by QCT vs DXA. Changes in trabecular bone resulted in increased indices of compressive strength. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1077-9Authors R. Eastell, University of Sheffield Academic Unit of Bone Metabolism Sheffield UKT. Lang, University of California Department of Radiology San Francisco USAS. Boonen, Katholieke Universiteit Leuven Leuven University Centre for Metabolic Bone Diseases and Division of Geriatric Medicine Leuven BelgiumS. Cummings, University of California CPMC Research Institute San Francisco USAP. D. Delmas, INSERM Research Unit 831 and University of Lyon Lyon FranceJ. A. Cauley, University of Pittsburgh Department of Epidemiolo... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2864312 Sat, 03 Oct 2009 06:32:51 +0100 2864312 Population-based Canadian hip fracture rates with international comparisons http://www.medworm.com/index.php?rid=2864314&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F018401300mx81845%2F Conclusions  Overall hip fracture rates for Canadian women were found to be substantially lower than those for the USA and Germany. This study underscores the importance of assessing country-specific fracture patterns prior to adopting an existing FRAX tool. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1080-1Authors W. D. Leslie, University of Manitoba Faculty of Medicine, Department of Medicine (C5121) 409 Tache Avenue Winnipeg Manitoba R2H 2A6 CanadaS. O’Donnell, Public Health Agency of Canada Ottawa CanadaC. Lagacé, Public Health Agency of Canada Ottawa CanadaP. Walsh, Public Health Agency of Canada Ottawa CanadaC. Bancej, Public Health Agency of Canada Ottawa CanadaS. Jean, Institut National de Santé Publique du Québec Quebec City... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2864314 Sat, 03 Oct 2009 06:32:50 +0100 2864314 Calcium supplementation for older men and women? http://www.medworm.com/index.php?rid=2864315&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F7612u2k659613v66%2F Content Type Journal ArticleCategory LetterDOI 10.1007/s00198-009-1072-1Authors M. J. Bolland, University of Auckland Department of Medicine Private Bag 92019 Auckland 1020 New ZealandA. B. Grey, University of Auckland Department of Medicine Private Bag 92019 Auckland 1020 New ZealandI. R. Reid, University of Auckland Department of Medicine Private Bag 92019 Auckland 1020 New Zealand Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2864315 Sat, 03 Oct 2009 06:32:49 +0100 2864315 “The effect of calcium supplementation on bone loss in 32 controlled trials in postmenopausal women”: response to comments http://www.medworm.com/index.php?rid=2864316&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn597756p03g4103n%2F Content Type Journal ArticleCategory LetterDOI 10.1007/s00198-009-1074-zAuthors B. E. C. Nordin, Royal Adelaide Hospital Endocrine & Metabolic Unit Adelaide South Australia AustraliaP. Keane, Library, Royal Adelaide Hospital Adelaide South Australia AustraliaA. Metcalfe, The University of Adelaide School of Mathematical Sciences Adelaide South Australia Australia Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2864316 Sat, 03 Oct 2009 06:32:48 +0100 2864316 Effects of arzoxifene on bone, lipid markers, and safety parameters in postmenopausal women with low bone mass http://www.medworm.com/index.php?rid=2864317&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F343814763102h222%2F Conclusions  Arzoxifene suppressed bone turnover and increased BMD. Within the limitations of this study, the endometrial safety profile of arzoxifene appeared similar to that of raloxifene. While no clear dose effect was evident, arzoxifene 20 and 40 mg/day appeared the optimal doses for reducing bone turnover. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1060-5Authors R. W. Downs, Virginia Commonwealth University Program for Osteoporosis and Bone Health, Division of Endocrinology and Metabolism 1101 E Marshall Street, 7-015 P.O. Box 980111 Richmond VA 23298-0111 USAA. M. Moffett, OB/GYN Associates Mid Florida Leesburg FL USAA. Ghosh, Johnson & Johnson Raritan NJ USAD. A. Cox, Eli Lilly and Company Indianapolis IN USAS. A. Dowsett,... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2864317 Thu, 01 Oct 2009 18:13:39 +0100 2864317 Predictors of oral bisphosphonate prescriptions in post-menopausal women with osteoporosis in a real-world setting in the USA http://www.medworm.com/index.php?rid=2864318&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa24703070v4361t6%2F Conclusion  Certain patient characteristics are predictors of physicians prescribing oral bisphosphonates. However, many patients remain untreated. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1079-7Authors C. Asche, University of Utah School of Medicine Salt Lake UT USAR. Nelson, University of Utah School of Medicine Salt Lake UT USAC. McAdam-Marx, University of Utah School of Medicine Salt Lake UT USAM. Jhaveri, Sanofi-Aventis Bridgewater NJ USAX. Ye, University of Utah School of Medicine Salt Lake UT USA Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2864318 Thu, 01 Oct 2009 18:13:36 +0100 2864318 BMD T-score discriminates trochanteric fractures from unfractured controls, whereas geometry discriminates cervical fracture cases from unfractured controls of similar BMD http://www.medworm.com/index.php?rid=2849037&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh877x45757kg6716%2F Conclusions  The study suggests that the risk of trochanteric fractures could be discriminated based on a BMD T-score <−2.5 criterion, whereas cervical fracture cases would remain under-diagnosed if solely using this criterion. Instead, geometrical risk factors are able to discriminate cervical fracture cases even among individuals with T-score >−2.5. For cervical and trochanteric fractures combined, BMD and geometric measures independently contributed to hip fracture discrimination. Our data support changing from T-score <−2.5 to a more comprehensive assessment of hip fracture etiology, in which fracture type is also taken into account. The findings need to be confirmed with a larger sample, preferably in a prospective study. Content Type Journal Artic... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2849037 Tue, 29 Sep 2009 01:06:04 +0100 2849037 Sarcopenia: etiology, clinical consequences, intervention, and assessment http://www.medworm.com/index.php?rid=2835652&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F6537k81j8328807p%2F Abstract  The aging process is associated with loss of muscle mass and strength and decline in physical functioning. The term sarcopenia is primarily defined as low level of muscle mass resulting from age-related muscle loss, but its definition is often broadened to include the underlying cellular processes involved in skeletal muscle loss as well as their clinical manifestations. The underlying cellular changes involve weakening of factors promoting muscle anabolism and increased expression of inflammatory factors and other agents which contribute to skeletal muscle catabolism. At the cellular level, these molecular processes are manifested in a loss of muscle fiber cross-sectional area, loss of innervation, and adaptive changes in the proportions of slow and fast motor un... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2835652 Thu, 24 Sep 2009 16:45:03 +0100 2835652 Low-energy distal radius fractures in middle-aged and elderly women—seasonal variations, prevalence of osteoporosis, and associates with fractures http://www.medworm.com/index.php?rid=2833508&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu3134h4250r71465%2F Conclusions  Our study highlights that environmental factor, as well as osteoporosis are associated with distal radius fractures in middle-aged and elderly women. Osteoporosis is also frequently found in outdoor patients, thus, all female distal radius fracture patients ≥50 years should be referred for osteoporosis assessment. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1065-0Authors J. Øyen, University of Bergen Department of Surgical Sciences, Faculty of Medicine and Dentistry Bergen NorwayG. E. Rohde, Sørlandet Hospital Department of Rheumatology Kristiansand Service box 416 4604 Kristiansand NorwayM. Hochberg, University of Maryland School of Medicine Departments of Medicine and Epidemiology and Preventive Medicine Baltimor... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2833508 Wed, 23 Sep 2009 06:03:06 +0100 2833508 Independent from muscle power and balance performance, a creatinine clearance below 65 ml/min is a significant and independent risk factor for falls and fall-related fractures in elderly men and women diagnosed with osteoporosis http://www.medworm.com/index.php?rid=2833510&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc446r62062004p1n%2F Conclusions  In this study, we found a significant gender-independent correlation between decreasing CrCl and lower performance in balance and muscle power tests. Reduced muscle power and balance may therefore be involved in the low creatinine clearance associated increased risk for falls and fall-related fractures. Furthermore, we found that a CrCl <65 ml/min., independent from the performance in muscle power, muscle function, and balance tests, is a significant risk factor for falls and fractures. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1064-1Authors L. Dukas, Acute Geriatric University Clinic Department of Medicine Basel SwitzerlandE. Schacht, Zürich Osteoporosis Research Group ZORG Zollikerberg SwitzerlandM. Runge, Aerp... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2833510 Tue, 22 Sep 2009 15:40:32 +0100 2833510 Prior nonhip limb fracture predicts subsequent hip fracture in institutionalized elderly people http://www.medworm.com/index.php?rid=2833509&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl437463864360723%2F Conclusions  A fracture history at upper or nonhip lower limbs, in combination with other known risk factors, is useful for the prediction of future hip fracture in institutional settings. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1081-0Authors K. Nakamura, Niigata University Graduate School of Medical and Dental Sciences Department of Community Preventive Medicine 1-757 Asahimachi-dori, Chuo-ku Niigata 951-8510 JapanS. Takahashi, Niigata University School of Medicine 1-757 Asahimachi-dori, Chuo-ku Niigata 951-8510 JapanM. Oyama, Niigata University Graduate School of Medical and Dental Sciences Department of Community Preventive Medicine 1-757 Asahimachi-dori, Chuo-ku Niigata 951-8510 JapanR. Oshiki, Niigata University of Health and Wel... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2833509 Tue, 22 Sep 2009 15:40:32 +0100 2833509 Micro-CT and mechanical evaluation of subchondral trabecular bone structure between postmenopausal women with osteoarthritis and osteoporosis http://www.medworm.com/index.php?rid=2833511&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F4m4631w39135t21p%2F Conclusions  We observed the difference in microstructure between postmenopausal women with OA and OP, which might relate to the opposite bone defects in OA and OP. BV/TV might play an important role in mechanical properties of the subchondral bone in either OA or OP. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1071-2Authors Z.-M. Zhang, Shanghai Jiaotong University School of Medicine Department of Orthopedic Surgery, Xinhua Hospital 1665 Kongjiang Road Shanghai 200092 ChinaZ.-C. Li, Shanghai Jiaotong University School of Medicine Department of Orthopedic Surgery, Xinhua Hospital 1665 Kongjiang Road Shanghai 200092 ChinaL.-S. Jiang, Shanghai Jiaotong University School of Medicine Department of Orthopedic Surgery, Xinhua Hospital 1665 Kon... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2833511 Tue, 22 Sep 2009 15:40:31 +0100 2833511 Erratum to: Bone mineral: update on chemical composition and structure http://www.medworm.com/index.php?rid=2811189&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj386338q648v37w2%2F Content Type Journal ArticleCategory ErratumDOI 10.1007/s00198-009-1063-2Authors C. Rey, University of Toulouse, CIRIMAT, ENSIACET 118 Route de Narbonne 31077 Toulouse Cedex 04 FranceC. Combes, University of Toulouse, CIRIMAT, ENSIACET 118 Route de Narbonne 31077 Toulouse Cedex 04 FranceC. Drouet, University of Toulouse, CIRIMAT, ENSIACET 118 Route de Narbonne 31077 Toulouse Cedex 04 FranceM. J. Glimcher, Harvard Medical School and Children’s Hospital Boston Laboratory for the Study of Skeletal Disorders and Rehabilitation, Department of Orthopaedic Surgery 300 Longwood Ave Boston MA 02115 USA Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2811189 Thu, 17 Sep 2009 12:44:39 +0100 2811189 Collagen cross-links as a determinant of bone quality: a possible explanation for bone fragility in aging, osteoporosis, and diabetes mellitus http://www.medworm.com/index.php?rid=2811188&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft1w3k4xp82020j57%2F Abstract  Collagen cross-linking, a major post-translational modification of collagen, plays important roles in the biological and biomechanical features of bone. Collagen cross-links can be divided into lysyl hydroxylase and lysyl oxidase-mediated enzymatic immature divalent cross-links, mature trivalent pyridinoline and pyrrole cross-links, and glycation- or oxidation-induced non-enzymatic cross-links (advanced glycation end products) such as glucosepane and pentosidine. These types of cross-links differ in the mechanism of formation and in function. Material properties of newly synthesized collagen matrix may differ in tissue maturity and senescence from older matrix in terms of cross-link formation. Additionally, newly synthesized matrix in osteoporotic patients or diab... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2811188 Thu, 17 Sep 2009 12:44:39 +0100 2811188 Adjustment for body mass index and calcitrophic hormone levels improves the diagnostic accuracy of the spot urine calcium-to-creatinine ratio http://www.medworm.com/index.php?rid=2811187&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb736331474r63242%2F Conclusions  We conclude that the SUCCR underestimates urine calcium loss and does not reliably diagnose hypercalciuria. A formula derived from multivariate regression incorporating other readily measurable variables greatly improved the SUCCR’s accuracy. Future studies must verify this correction before clinical implementation. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1058-zAuthors A. N. Jones, University of Wisconsin School of Medicine and Public Health Department of Medicine 600 Highland Avenue Madison WI 53792 USAR. D. Blank, University of Wisconsin School of Medicine and Public Health Department of Medicine 600 Highland Avenue Madison WI 53792 USAM. J. Lindstrom, University of Wisconsin Department of Biostatistics and Medical I... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2811187 Thu, 17 Sep 2009 12:44:39 +0100 2811187 Bisphosphonates and BMU birth rate: response to comments by Ott http://www.medworm.com/index.php?rid=2811190&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa745006630243m87%2F Content Type Journal ArticleCategory LetterDOI 10.1007/s00198-009-1027-6Authors E. Seeman, University of Melbourne Department of Endocrinology, Austin Health Melbourne Australia Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2811190 Thu, 17 Sep 2009 12:44:38 +0100 2811190 Assessing interest in an osteoporosis website: a survey among women eligible for osteoporosis screening http://www.medworm.com/index.php?rid=2811191&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F74122589763337kg%2F Conclusions  These data suggest that middle-aged women are moderately receptive to the concept of web-based care for certain components of osteoporosis management and education. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1054-3Authors Y. Rozenfeld, Providence Health & Services Portland OR USAT. Johnson, Providence Health & Services Portland OR USAC. Klug, Providence Health & Services Portland OR USA Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2811191 Tue, 15 Sep 2009 20:50:15 +0100 2811191 Is there a U-shaped association between physical activity and falling in older persons? http://www.medworm.com/index.php?rid=2811194&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F663476712038552u%2F Conclusions  The hypothesized U-shaped relationship between physical activity and falling could not be confirmed. At higher levels of physical activity, the risk of recurrent falling decreased, while no association was found with fall risk. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1053-4Authors G. M. E. E. Peeters, VU University Medical Center Department of Epidemiology and Biostatistics, EMGO Institute for Health and Care Research Amsterdam the NetherlandsN. M. van Schoor, VU University Medical Center Department of Epidemiology and Biostatistics, EMGO Institute for Health and Care Research Amsterdam the NetherlandsS. M. F. Pluijm, Erasmus MC Department of Public Health Rotterdam the NetherlandsD. J. H. Deeg, VU University Medical Cent... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2811194 Tue, 15 Sep 2009 20:50:14 +0100 2811194 Hip structural geometry and incidence of hip fracture in postmenopausal women: what does it add to conventional bone mineral density? http://www.medworm.com/index.php?rid=2811193&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe6v602kp47527t17%2F Conclusions  Two hip geometry parameters, intertrochanter outer diameter and buckling ratio, predict incident hip fracture after accounting for clinical risk factors and aBMD. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1056-1Authors A. Z. LaCroix, Fred Hutchinson Cancer Research Center WHI Clinical Coordinating Center Seattle WA USAT. J. Beck, The Johns Hopkins University Department of Radiology Baltimore MD USAJ. A. Cauley, University of Pittsburgh Department of Epidemiology Pittsburgh PA USAC. E. Lewis, University of Alabama Division of Preventive Medicine Birmingham AL USAT. Bassford, University of Arizona Department of Family and Community Medicine Tucson AZ USAR. Jackson, Ohio State University Division of Endocrinology Columbus OH U... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2811193 Tue, 15 Sep 2009 20:50:14 +0100 2811193 Measurement uncertainty of 25-OH vitamin D determination with different commercially available kits: impact on the clinical cut offs http://www.medworm.com/index.php?rid=2811192&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn40k4x267683q3h6%2F Conclusions  Our results show that, whatever the assay, the “true” 25(OH)D of a patient will be >80 nmol/L if its measured concentration is >100 nmol/L. In other words, if a physician considers that a normal VTD status is defined by a 25(OH)D level ≥80 nmol/L, he should ensure that the patients present a 25(OH)D ≥100 nmol/L. Content Type Journal ArticleCategory Short CommunicationDOI 10.1007/s00198-009-1052-5Authors E. Cavalier, University Hospital of Liège Department of Clinical Chemistry Domaine du Sart-Tilman 4000 Liège BelgiumE. Rozet, University of Liège Department of Analytical Chemistry Liège BelgiumR. Gadisseur, University Hospital of Liège Department of Clinical Chemistry Domaine du Sart-Tilman 4000 Liège BelgiumA. Carli... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2811192 Tue, 15 Sep 2009 20:50:14 +0100 2811192 Selecting men for bone densitometry: performance of osteoporosis risk assessment tools in Portuguese men http://www.medworm.com/index.php?rid=2767665&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy086136374062442%2F Conclusions  OP risk assessment tools seem to be useful in men aged 50 or more. Best cutoff values are different from those recommended for postmenopausal women. Different cutoff values may be appropriate for different countries and/or ethnic origins. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1036-5Authors P. Machado, Coimbra University Hospital Rheumatology Department Coimbra PortugalM. Coutinho, Coimbra University Hospital Rheumatology Department Coimbra PortugalJ. A. P. da Silva, Coimbra University Hospital Rheumatology Department Coimbra Portugal Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2767665 Thu, 03 Sep 2009 06:31:43 +0100 2767665 A call to action: developing and implementing a national action plan to improve bone health http://www.medworm.com/index.php?rid=2767664&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F068597n532v60024%2F Content Type Journal ArticleCategory EditorialDOI 10.1007/s00198-009-1041-8Authors L. G. Raisz, University of Connecticut Health Center 263 Farmington Avenue Farmington CT 06030 USAA. L. Elderkin, American Society for Bone and Mineral Research Washington DC USAL. Schargorodski, National Osteoporosis Foundation Washington DC USAT. Hart, Osteogenesis Imperfecta Foundation Gaithersburg MD USAC. Waldman, The Paget Foundation New York NY USAT. King, United States Bone and Joint Decade Chicago IL USAA. S. Noonan, Morgan State University School of Public Health Baltimore MD USA Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2767664 Thu, 03 Sep 2009 06:31:43 +0100 2767664 Impact of supplementation with bicarbonate on lower-extremity muscle performance in older men and women http://www.medworm.com/index.php?rid=2767667&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx34t3v1hh42u4w64%2F Conclusions  Ingestion of bicarbonate decreased nitrogen excretion and improved muscle performance in healthy postmenopausal women. The bicarbonate-induced decline in NAE was associated with reduced nitrogen excretion in both men and women. These findings suggest that bicarbonate merits further evaluation as a safe, low-cost intervention that may attenuate age-related loss of muscle performance and mass in the elderly. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1049-0Authors B. Dawson-Hughes, Tufts University Jean Mayer United States Department of Agriculture Human Nutrition Research Center on Aging Boston MA 02111 USAC. Castaneda-Sceppa, Northeastern University Bouve College of Health Sciences Boston MA 02115 USAS. S. Harris, Tufts Un... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2767667 Thu, 03 Sep 2009 06:31:41 +0100 2767667 Common variants in FLNB/CRTAP, not ARHGEF3 at 3p, are associated with osteoporosis in southern Chinese women http://www.medworm.com/index.php?rid=2767666&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F757u87700732x58h%2F Conclusions  Our data suggest that variants in FLNB and CRTAP at 3p are involved in BMD regulation in southern Chinese. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1043-6Authors G. H. Y. Li, The University of Hong Kong Department of Medicine Pokfulam Hong KongA. W. C. Kung, The University of Hong Kong Department of Medicine Pokfulam Hong KongQ.-Y. Huang, The University of Hong Kong Department of Medicine Pokfulam Hong Kong Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2767666 Thu, 03 Sep 2009 06:31:41 +0100 2767666 Bone status of adolescent girls in Pune (India) compared to age-matched South Asian and white Caucasian girls in the UK http://www.medworm.com/index.php?rid=2767669&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fwr18111q36u11255%2F Conclusion  Pune girls had low bone mass for projected BA relative to UK South Asian and white Caucasian girls, but had the appropriate amount of BMC for their LBM. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1040-9Authors A. Khadilkar, Jehangir Hospital Hirabai Cowasji Jehangir Medical Research Institute Pune IndiaN. J. Crabtree, Birmingham Children’s Hospital Department of Paediatric Endocrinology Birmingham UKK. A. Ward, MRC Human Nutrition Research Nutrition and Bone Health Research Group, Elsie Widdowson Laboratory Fulbourn Road Cambridge CB1 9NL UKV. Khadilkar, Jehangir Hospital Hirabai Cowasji Jehangir Medical Research Institute Pune IndiaN. J. Shaw, Birmingham Children’s Hospital Department of Paediatric Endocrinology Birmingh... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2767669 Thu, 03 Sep 2009 06:31:40 +0100 2767669 Dietary habit and bone mineral density in Korean postmenopausal women http://www.medworm.com/index.php?rid=2767668&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F686u833810151866%2F Conclusion  These results suggest that adequate nutrient intake is essential to maintain bone health in postmenopausal women. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1039-2Authors A. Shin, National Cancer Center Cancer Epidemiology Branch, Division of Cancer Epidemiology and Management, Research Institute 111 Jungbalsan-ro, Ilsandong-gu, Goyang-si Gyeonggi-do 410-769 KoreaS. Lim, National Cancer Center Cancer Epidemiology Branch, Division of Cancer Epidemiology and Management, Research Institute 111 Jungbalsan-ro, Ilsandong-gu, Goyang-si Gyeonggi-do 410-769 KoreaJ. Sung, School of Public Health, Seoul National University Department of Epidemiology and Institute of Health and Environment 28 Yongun-dong, Jongno-gu Seoul 110-799 KoreaS. M... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2767668 Thu, 03 Sep 2009 06:31:40 +0100 2767668 Longitudinal change in clinical fracture incidence after initiation of bisphosphonates http://www.medworm.com/index.php?rid=2755317&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ffl812qg63414g477%2F Conclusions  Differences in the baseline fracture incidence among the cohorts may reflect differences in the risk profile of patients prescribed each bisphosphonate. The reductions observed in fracture incidence over time within each cohort suggest that the effectiveness of each bisphosphonate in clinical practice has been consistent with their efficacies demonstrated in randomized controlled trials. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1046-3Authors A. Abelson, Cleveland Clinic Mail Code A50 9500 Euclid Avenue Cleveland OH 44195 USAJ. D. Ringe, University of Cologne Medizinische Klinik IV, Klinikum Leverkusen Cologne GermanyD. T. Gold, Duke University Medical Center Durham NC USAJ. L. Lange, Procter & Gamble Mason OH USAT. Thoma... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2755317 Mon, 31 Aug 2009 16:18:21 +0100 2755317 Assessing forearm fracture risk in postmenopausal women http://www.medworm.com/index.php?rid=2745113&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb846g6179u5343v2%2F Conclusions  Detailed bone structure and strength measurements provide insight into forearm fracture pathogenesis, but femoral neck aBMD performs adequately for routine clinical risk assessment. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1047-2Authors L. J. Melton, College of Medicine, Mayo Clinic Division of Epidemiology, Department of Health Sciences Research 200 First Street Southwest Rochester MN 55905 USAD. Christen, ETH Zurich Institute for Biomechanics Zurich SwitzerlandB. L. Riggs, College of Medicine, Mayo Clinic Division of Endocrinology, Metabolism and Nutrition, Department of Internal Medicine 200 First Street Southwest Rochester MN 55905 USAS. J. Achenbach, College of Medicine, Mayo Clinic Division of Biomedical Statistics a... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2745113 Fri, 28 Aug 2009 14:56:31 +0100 2745113 Bone mineral density reference ranges for Australian men: Geelong Osteoporosis Study http://www.medworm.com/index.php?rid=2736248&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy7813700238x7765%2F Conclusions  These data supply BMD reference ranges at multiple anatomical sites that will be applicable to white Australian men and similar populations such as USA non-Hispanic white men. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1042-7Authors M. J. Henry, The University of Melbourne Epidemiology & Biostatistics Unit, Department Clinical & Biomedical Sciences: Barwon Health P.O. Box 281 Geelong 3220 AustraliaJ. A. Pasco, The University of Melbourne Epidemiology & Biostatistics Unit, Department Clinical & Biomedical Sciences: Barwon Health P.O. Box 281 Geelong 3220 AustraliaS. Korn, The University of Melbourne Epidemiology & Biostatistics Unit, Department Clinical & Biomedical Sciences: Barwon Health P.O. Box 281 Geelong 3220 Austral... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2736248 Tue, 25 Aug 2009 16:47:25 +0100 2736248 Longitudinal changes in femur bone mineral density after spinal cord injury: effects of slice placement and peel method http://www.medworm.com/index.php?rid=2736247&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F850x34qx1r070141%2F Conclusions  Femur metaphysis BMD declines after SCI in a manner similar to other anatomic sites. Concentric (percentage-based) peel methods may be most appropriate when special sensitivity is required to detect BMD adaptations. Threshold-based methods may be more appropriate when asymmetric adaptations are observed. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1044-5Authors S. Dudley-Javoroski, The University of Iowa Graduate Program in Physical Therapy and Rehabilitation Science 1-252 Medical Education Building Iowa City IA 52242-1190 USAR. K. Shields, The University of Iowa Graduate Program in Physical Therapy and Rehabilitation Science 1-252 Medical Education Building Iowa City IA 52242-1190 USA Journal Osteoporosis Internation... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2736247 Tue, 25 Aug 2009 16:47:25 +0100 2736247 A pilot case–control study on the alveolar bone density measurement in risk assessment for bisphosphonate-related osteonecrosis of the jaw http://www.medworm.com/index.php?rid=2732487&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj170l390p1366020%2F Conclusion  This method may be useful in detecting a rise of alveolar BMD frequently occurring near the necrotic lesion in subjects with impending risk for BRONJ. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1021-zAuthors Y. Takaishi, Takaishi Dental Clinic 3-32, Hojo-guchi Himeji 670-0935 JapanT. Ikeo, Osaka Dental University Department of Biochemistry Osaka JapanM. Nakajima, Osaka Dental University Department of Oral and Maxillofacial Surgery Osaka JapanT. Miki, Osaka City University Department of Geriatric Medicine Osaka JapanT. Fujita, Katsuragi Hospital Osaka Japan Journal Osteoporosis InternationalOnline ISSN 1433-2965Print ISSN 0937-941X (Source: Osteoporosis International) Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2732487 Mon, 24 Aug 2009 16:54:53 +0100 2732487 The effects of a FRAX® revision for the USA http://www.medworm.com/index.php?rid=2732488&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F23l44766192w1562%2F Conclusion  The revised FRAX® model for the USA (version 3.0) does not alter the ranking of fracture probabilities but provides lower probability estimates than version 2.0, particularly, in younger women and men. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1033-8Authors J. A. Kanis, University of Sheffield Medical School WHO Collaborating Centre for Metabolic Bone Diseases Beech Hill Road Sheffield S10 2RX UKH. Johansson, University of Sheffield Medical School WHO Collaborating Centre for Metabolic Bone Diseases Beech Hill Road Sheffield S10 2RX UKA. Oden, University of Sheffield Medical School WHO Collaborating Centre for Metabolic Bone Diseases Beech Hill Road Sheffield S10 2RX UKB. Dawson-Hughes, Tufts University Jean Mayer US Depart... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2732488 Mon, 24 Aug 2009 16:54:52 +0100 2732488 The potential impact of new National Osteoporosis Foundation guidance on treatment patterns http://www.medworm.com/index.php?rid=2732489&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr704018486712235%2F Conclusions  One fifth of men and 37% of postmenopausal women are eligible for osteoporosis treatment consideration by the new NOF Guide. However, fewer NHW women are eligible by the new guide than by the previous NOF Guide. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1034-7Authors B. Dawson-Hughes, Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University 711 Washington Street Boston MA 02111 USAA. C. Looker, Centers for Disease Control and Prevention National Center for Health Statistics Hyattsville MD USAA. N. A. Tosteson, Dartmouth Medical School Multidisciplinary Clinical Research Center in Musculoskeletal Diseases and The Dartmouth Institute for Health Policy and Clinical Practice Lebanon NH USAH. Johansson, Unive... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2732489 Mon, 24 Aug 2009 16:54:51 +0100 2732489 Updated fracture incidence rates for the US version of FRAX® http://www.medworm.com/index.php?rid=2732490&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq782l30v7q435571%2F Conclusions  We recommend revising the US-FRAX by updating current base population values for hip fracture and major osteoporotic fracture. The impact of these revisions on FRAX® is likely to be lowering of 10-year fracture probabilities, but more precise estimates of the impact of these changes will be available after these new rates are incorporated into the FRAX® tool. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1032-9Authors B. Ettinger, Kaiser Permanente Medical Care Program Division of Research Oakland CA USAD. M. Black, University of California Department of Epidemiology & Biostatistics San Francisco CA USAB. Dawson-Hughes, Tufts University Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging Boston M... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2732490 Mon, 24 Aug 2009 16:54:48 +0100 2732490 Bone loss in relation to serum levels of osteoprotegerin and nuclear factor-κB ligand: the Tromsø Study http://www.medworm.com/index.php?rid=2723777&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F6182t32658816l33%2F Conclusions  In postmenopausal women not using HRT, bone loss associated positively with OPG. The results indicate that in women deficient in sex steroids, the OPG/RANKL system may play an important counter regulatory role in order to avoid bone loss and maintain BMD. In men and women replete in sex steroids, the OPG/RANKL system was not associated with BMD. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1035-6Authors L. Jørgensen, University of Tromsø Institute of Community Medicine 9037 Tromsø NorwayA. Vik, University of Tromsø Center for Atherothrombotic Research in Tromsø (CART), Institute of Clinical Medicine Tromsø NorwayN. Emaus, University of Tromsø Institute of Community Medicine 9037 Tromsø NorwayJ. Brox, University of Tro... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2723777 Fri, 21 Aug 2009 17:06:16 +0100 2723777 Femur ultrasound (FemUS)—first clinical results on hip fracture discrimination and estimation of femoral BMD http://www.medworm.com/index.php?rid=2722228&cid=s_33316_31_f&fid=33316&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd38h13p525540u78%2F Conclusions  QUS measurements at the proximal femur are feasible and show a good performance for hip fracture discrimination. Given the promising results, this laboratory prototype should be reengineered to a clinical applicable instrument. Our results show promise for further enhancement of QUS-based assessment of osteoporosis. Content Type Journal ArticleCategory Original ArticleDOI 10.1007/s00198-009-1037-4Authors R. Barkmann, Universitätsklinikum Schleswig-Holstein Arbeitsgruppe Medizinische Physik, Klinik für Diagnostische Radiologie Arnold-Heller-Str. 3, Haus 23 24105 Kiel GermanyS. Dencks, Physikalisch-Technische Bundesanstalt Braunschweig GermanyP. Laugier, Université Pierre et Marie Curie Laboratoire d’Imagerie Paramétrique Paris FranceF. Padilla, Univer... Osteoporosis International journals http://www.medworm.com/rss/comments.php?id=2722228 Thu, 20 Aug 2009 08:34:17 +0100 2722228