MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'PEDIATRICS' source. Thu, 09 Feb 2012 01:09:41 +0100 http://www.medworm.com/index.php?rid=5651262&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Ffull%2F129%2F2%2Fe568%3Frss%3D1 (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651262 Wed, 01 Feb 2012 05:00:00 +0100 5651262 http://www.medworm.com/index.php?rid=5651261&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Ffull%2F129%2F2%2Fe567%3Frss%3D1 (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651261 Wed, 01 Feb 2012 05:00:00 +0100 5651261 http://www.medworm.com/index.php?rid=5651260&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe562%3Frss%3D1 Although most health care services can and should be provided by their medical home, children will be referred or require visits to the emergency department (ED) for emergent clinical conditions or injuries. Continuation of medical care after discharge from an ED is dependent on parents or caregivers’ understanding of and compliance with follow-up instructions and on adherence to medication recommendations. ED visits often occur at times when the majority of pharmacies are not open and caregivers are concerned with getting their ill or injured child directly home. Approximately one-third of patients fail to obtain priority medications from a pharmacy after discharge from an ED. The option of judiciously dispensing ED discharge medications from the ED’s outpatient pharmacy withi... PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651260 Wed, 01 Feb 2012 05:00:00 +0100 5651260 http://www.medworm.com/index.php?rid=5651259&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Ffull%2F129%2F2%2Fe561%3Frss%3D1 (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651259 Wed, 01 Feb 2012 05:00:00 +0100 5651259 http://www.medworm.com/index.php?rid=5651258&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe540%3Frss%3D1 Maternal use of certain drugs during pregnancy can result in transient neonatal signs consistent with withdrawal or acute toxicity or cause sustained signs consistent with a lasting drug effect. In addition, hospitalized infants who are treated with opioids or benzodiazepines to provide analgesia or sedation may be at risk for manifesting signs of withdrawal. This statement updates information about the clinical presentation of infants exposed to intrauterine drugs and the therapeutic options for treatment of withdrawal and is expanded to include evidence-based approaches to the management of the hospitalized infant who requires weaning from analgesics or sedatives. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651258 Wed, 01 Feb 2012 05:00:00 +0100 5651258 http://www.medworm.com/index.php?rid=5651257&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe535%3Frss%3D1 Mevalonic aciduria (MA) represents the severest form of mevalonate kinase deficiency due to recessively inherited, loss-of-function MVK mutations. MA is an early-onset disorder characterized by a marked failure to thrive, diverse neurologic symptoms, dysmorphic features, and recurrent febrile episodes. However, significant clinical differences have been reported in the few cases published to date. Here we describe 2 unrelated Spanish patients with MA, emphasizing the clinical heterogeneity observed. One patient presented with the severe classic MA phenotype due to the homozygous p.Ile-268-Thr MVK genotype, with a poor response to conventional treatments. However, the anti-interleukin 1 agent anakinra in this patient resulted in improvement in many clinical and laboratory parameters. The se... PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651257 Wed, 01 Feb 2012 05:00:00 +0100 5651257 http://www.medworm.com/index.php?rid=5651256&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe529%3Frss%3D1 We report on a neonate with unexplained heart failure and minor physical anomalies, suggesting a midline defect. She was diagnosed with complete CPHD. Cardiac function was rescued by replacement with hydrocortisone and thyroxine; hypoglycaemia stopped under growth hormone therapy. Magnetic resonance imaging revealed a dysgenetic pituitary gland suggesting an early developmental defect. Array comparative genomic hybridization showed a maternally inherited 1.5-megabase microdeletion in 1q25.2q25.3, including the LHX4 gene. Haploinsufficiency of LHX4 likely explains the predominant pituitary phenotype in the proposita and we suggest variable intrafamilial penetrance of the inherited microdeletion. To the best of our knowledge, we are the first to report on heart failure as a rare nonspecific ... PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651256 Wed, 01 Feb 2012 05:00:00 +0100 5651256 http://www.medworm.com/index.php?rid=5651255&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe523%3Frss%3D1 We present a patient lacking the typical symptoms of XLP-1, but experiencing a severe unusual skin condition encompassing features of dermatosclerosis and vesiculobullous skin disease. A maternal cousin of the patient was diagnosed with XLP-1 and found to carry a deletion of the SH2D1A gene. SH2D1A deletion was also identified in our patient, which offered a possible explanation for his skin symptoms. Subsequent analysis showed that the deletion in both cousins was identical and involved the whole SH2D1A gene and a part of the adjacent ODZ1 gene. High phenotypic variability of XLP-1 observed in this family prompted us to analyze the genotype-phenotype correlation of 2 different-sized deletions involving SH2D1A and ODZ1 in 5 patients from 2 families, and we report the clinical and laborator... PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651255 Wed, 01 Feb 2012 05:00:00 +0100 5651255 http://www.medworm.com/index.php?rid=5651254&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe519%3Frss%3D1 We describe herein a case of severe cytokine dermatitis in a 2-year-old female patient treated with daily imiquimod for molluscum contagiosum who subsequently developed febrile seizure. We believe this to be the first reported case of seizure associated with imiquimod 5% cream (Aldara, 3M) in a pediatric setting. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651254 Wed, 01 Feb 2012 05:00:00 +0100 5651254 http://www.medworm.com/index.php?rid=5651253&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe515%3Frss%3D1 This report should alert the pediatrician that intestinal malrotation should be added to the wide list of possible causes of protein-losing enteropathy in children. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651253 Wed, 01 Feb 2012 05:00:00 +0100 5651253 http://www.medworm.com/index.php?rid=5651252&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe511%3Frss%3D1 We report the case of a 2-year-old girl who presented to the emergency department with 1-week history of decreased activity, polyuria, and decreased oral intake. Her past medical history was remarkable for epilepsy, for which she was started on the KD with a significant improvement. Her laboratory evaluation was compatible with DKA, and fluids and insulin were given until correction. Because of concerns regarding recurrence of her seizures, the KD was resumed along with the simultaneous use of insulin glargine and insulin aspart. Urine ketones were kept in the moderate range to keep the effect of ketosis on seizure control. Under this combined therapy, the patient remained seizure-free with no new episodes of DKA. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651252 Wed, 01 Feb 2012 05:00:00 +0100 5651252 http://www.medworm.com/index.php?rid=5651251&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe504%3Frss%3D1 CONCLUSIONS: Application of quality-improvement methods in a primary care clinic increased ability to effectively screen and positively identify households with food insecurity in this population. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651251 Wed, 01 Feb 2012 05:00:00 +0100 5651251 http://www.medworm.com/index.php?rid=5651250&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe496%3Frss%3D1 CONCLUSION: We were able to implement a comprehensive immunization QI program that was sustainable over time. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651250 Wed, 01 Feb 2012 05:00:00 +0100 5651250 http://www.medworm.com/index.php?rid=5651249&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Ffull%2F129%2F2%2Fe494%3Frss%3D1 (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651249 Wed, 01 Feb 2012 05:00:00 +0100 5651249 http://www.medworm.com/index.php?rid=5651248&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe486%3Frss%3D1 This article describes a multistate population-based surveillance system for monitoring sudden unexpected infant deaths (SUIDs) known as the SUID Case Registry pilot program. The pilot program represents collaboration between the Centers for Disease Control and Prevention and the National Center for Child Death Review (NCCDR), which is funded by the Health Resources and Services Administration. The SUID Case Registry builds on existing child death review system activities and protocols. The objectives of the SUID Case Registry are to collect accurate and consistent population-based data about the circumstances and events associated with SUID cases, to improve the completeness and quality of SUID case investigations, and to use a decision-making algorithm with standardized definitions to ca... PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651248 Wed, 01 Feb 2012 05:00:00 +0100 5651248 http://www.medworm.com/index.php?rid=5651247&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe473%3Frss%3D1 Self-management of chronic pediatric conditions is a formidable challenge for patients, families, and clinicians, with research demonstrating a high prevalence of poor self-management and nonadherence across pediatric conditions. Nevertheless, effective self-management is necessary to maximize treatment efficacy and clinical outcomes and to reduce unnecessary health care utilization and costs. However, this complex behavior is poorly understood as a result of insufficient definitions, reliance on condition-specific and/or adult models of self-management, failure to consider the multitude of factors that influence patient self-management behavior, and lack of synthesis of research, clinical practice, and policy implications. To address this need, we present a comprehensive conceptual model ... PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651247 Wed, 01 Feb 2012 05:00:00 +0100 5651247 http://www.medworm.com/index.php?rid=5651246&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe460%3Frss%3D1 Building a strong foundation for healthy development in the early years of life is a prerequisite for individual well-being, economic productivity, and harmonious societies around the world. Growing scientific evidence also demonstrates that social and physical environments that threaten human development (because of scarcity, stress, or instability) can lead to short-term physiologic and psychological adjustments that are necessary for immediate survival and adaptation, but which may come at a significant cost to long-term outcomes in learning, behavior, health, and longevity. Generally speaking, ministries of health prioritize child survival and physical well-being, ministries of education focus on schooling, ministries of finance promote economic development, and ministries of welfare a... PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651246 Wed, 01 Feb 2012 05:00:00 +0100 5651246 http://www.medworm.com/index.php?rid=5651245&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe455%3Frss%3D1 CONCLUSIONS: This high heritability estimate could suggest using this set of criteria to identify genes that regulate postnatal weight gain or failure. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651245 Wed, 01 Feb 2012 05:00:00 +0100 5651245 http://www.medworm.com/index.php?rid=5651244&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe447%3Frss%3D1 CONCLUSIONS: The proportion of infants experiencing adverse outcomes increased with the degree of epidural-related maternal temperature elevation. Epidural use without temperature elevation was not associated with any of the adverse outcomes we studied. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651244 Wed, 01 Feb 2012 05:00:00 +0100 5651244 http://www.medworm.com/index.php?rid=5651243&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe438%3Frss%3D1 CONCLUSIONS: These methods largely agree on percent EBW in terms of clinically significant cut points. However, the McLaren and Moore methods present with limitations, and a commonly agreed-upon method for EBW calculation such as the BMI percentile method is recommended for clinical and research purposes. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651243 Wed, 01 Feb 2012 05:00:00 +0100 5651243 http://www.medworm.com/index.php?rid=5651242&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe431%3Frss%3D1 CONCLUSIONS: These results can be used to improve our strategy in the evaluation of macroglossia. Distinction between isolated macroglossia and BWS may be difficult when only taking into account clinical features. These findings suggest that all patients with apparently isolated macroglossia have at least initial evaluation with abdominal ultrasounds and molecular studies for BWS before a final diagnosis is given. BWS was the most common cause of macroglossia even in the absence of additional clinical findings. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651242 Wed, 01 Feb 2012 05:00:00 +0100 5651242 http://www.medworm.com/index.php?rid=5651241&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe424%3Frss%3D1 CONCLUSIONS: A summer pertussis pseudo-outbreak, multifactorial in cause, likely occurred. Recommendations beyond standard practice were made to providers on specimen collection and environmental cleaning, and to laboratories on standardizing PCR protocols and reporting results, to minimize false-positive results from contaminated clinical specimens. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651241 Wed, 01 Feb 2012 05:00:00 +0100 5651241 http://www.medworm.com/index.php?rid=5651240&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe414%3Frss%3D1 CONCLUSIONS: Except for the prothrombin gene mutation, individual maternal and fetal SNPs in our candidate panel were not found to be associated with CP outcome. Past reported SNP associations with CP were not confirmed, possibly reflecting type I error from small numbers and multiple testing in the original reports. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651240 Wed, 01 Feb 2012 05:00:00 +0100 5651240 http://www.medworm.com/index.php?rid=5651239&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2F394%3Frss%3D1 Drawing on several decades of work with families, pediatricians, other health care professionals, and policy makers, the American Academy of Pediatrics provides a definition of patient- and family-centered care. In pediatrics, patient- and family-centered care is based on the understanding that the family is the child’s primary source of strength and support. Further, this approach to care recognizes that the perspectives and information provided by families, children, and young adults are essential components of high-quality clinical decision-making, and that patients and family are integral partners with the health care team. This policy statement outlines the core principles of patient- and family-centered care, summarizes some of the recent literature linking patient- and family-... PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651239 Wed, 01 Feb 2012 05:00:00 +0100 5651239 http://www.medworm.com/index.php?rid=5651238&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe392%3Frss%3D1 CONCLUSIONS: The prevalence of elevated blood lead levels among tested US-bound Burmese refugee children was higher than the current US prevalence, and was especially high among children <2 years old. Refugee children may arrive in the United States with elevated blood lead levels. A population-specific understanding of preexisting lead exposures can enhance postarrival lead-poisoning prevention efforts, based on Centers for Disease Control and Prevention recommendations for resettled refugee children, and can lead to remediation efforts overseas. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651238 Wed, 01 Feb 2012 05:00:00 +0100 5651238 http://www.medworm.com/index.php?rid=5651237&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2F387%3Frss%3D1 School-based health centers (SBHCs) have become an important method of health care delivery for the youth of our nation. Although they only represent 1 aspect of a coordinated school health program approach, SBHCs have provided access to health care services for youth confronted with age, financial, cultural, and geographic barriers. A fundamental principle of SBHCs is to create an environment of service coordination and collaboration that addresses the health needs and well-being of youth with health disparities or poor access to health care services. Some pediatricians have concerns that these centers are in conflict with the primary care provider’s medical home. This policy provides an overview of SBHCs and some of their documented benefits, addresses the issue of potential confli... PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651237 Wed, 01 Feb 2012 05:00:00 +0100 5651237 http://www.medworm.com/index.php?rid=5651236&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe385%3Frss%3D1 CONCLUSIONS: This multicenter observational analysis did not find any benefit associated with methylprednisolone in neonates undergoing heart surgery and suggested increased infection in certain subgroups. These data reinforce the need for a large randomized trial in this population. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651236 Wed, 01 Feb 2012 05:00:00 +0100 5651236 http://www.medworm.com/index.php?rid=5651235&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Ffull%2F129%2F2%2F385%3Frss%3D1 (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651235 Wed, 01 Feb 2012 05:00:00 +0100 5651235 http://www.medworm.com/index.php?rid=5651234&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe377%3Frss%3D1 CONCLUSIONS: Universal social-emotional screening in a busy pediatric practice is challenging. Significant percentages of children can be identified as being at risk for social-emotional problems, and colocation of a psychologist promotes the ability to effectively address young children’s social-emotional development within their medical home. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651234 Wed, 01 Feb 2012 05:00:00 +0100 5651234 http://www.medworm.com/index.php?rid=5651233&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe370%3Frss%3D1 CONCLUSIONS: These data suggest that the higher mortality observed at lower volume centers in children undergoing heart surgery may be related to a higher rate of mortality in those with postoperative complications, rather than a higher rate of complications alone. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651233 Wed, 01 Feb 2012 05:00:00 +0100 5651233 http://www.medworm.com/index.php?rid=5651232&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Ffull%2F129%2F2%2F365%3Frss%3D1 (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651232 Wed, 01 Feb 2012 05:00:00 +0100 5651232 http://www.medworm.com/index.php?rid=5651231&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe364%3Frss%3D1 CONCLUSIONS: Children who present with chronic wet cough are often found to have evidence of purulent bronchitis on bronchoscopy. This finding is often indicative of a bacterial lower airway infection in these children. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651231 Wed, 01 Feb 2012 05:00:00 +0100 5651231 http://www.medworm.com/index.php?rid=5651230&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe356%3Frss%3D1 CONCLUSIONS: This noninvasive test is ready for prospective validation in large cohorts with the aim of identifying those children with UTI and hydronephrosis in need of further invasive diagnostics, such as voiding cystourethrography, thus sparing most children without pathologic urinary proteome patterns from additional diagnostics. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651230 Wed, 01 Feb 2012 05:00:00 +0100 5651230 http://www.medworm.com/index.php?rid=5651229&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2F354%3Frss%3D1 Analgesic trials pose unique scientific, ethical, and practical challenges in pediatrics. Participants in a scientific workshop sponsored by the US Food and Drug Administration developed consensus on aspects of pediatric analgesic clinical trial design. The standard parallel-placebo analgesic trial design commonly used for adults has ethical and practical difficulties in pediatrics, due to the likelihood of subjects experiencing pain for extended periods of time. Immediate-rescue designs using opioid-sparing, rather than pain scores, as a primary outcome measure have been successfully used in pediatric analgesic efficacy trials. These designs maintain some of the scientific benefits of blinding, with some ethical and practical advantages over traditional designs. Preferred outcome measures... PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651229 Wed, 01 Feb 2012 05:00:00 +0100 5651229 http://www.medworm.com/index.php?rid=5651228&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2F349%3Frss%3D1 An intravenous formulation of acetaminophen was introduced to the United States in 2011. Experience from Europe indicates that serious dosing errors are likely to occur. Most events have involved a 10-fold dosing error in small children caused by calculating the dosage in milligrams, but then administering the solution in milliliters. The solution is 10 mg/mL; therefore, a 10-fold overdose occurs. Evaluation of overdose with the intravenous formulation is similar to oral overdose. A serum acetaminophen concentration should be drawn 4 hours after the infusion was started or as soon thereafter as possible. If the serum acetaminophen concentration plots above the treatment line on the Rumack-Matthew nomogram, treatment with acetylcysteine should be initiated. Health care providers are encoura... PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651228 Wed, 01 Feb 2012 05:00:00 +0100 5651228 http://www.medworm.com/index.php?rid=5651227&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe348%3Frss%3D1 CONCLUSIONS: Children diagnosed with CF after newborn screening benefited from better lung function and BMI than those diagnosed clinically. The benefit of newborn screening on lung function was significantly less in Australian children compared with US children. Statistical comparisons between CF registries are feasible and can contribute to benchmarking and improvements in care. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651227 Wed, 01 Feb 2012 05:00:00 +0100 5651227 http://www.medworm.com/index.php?rid=5651226&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe339%3Frss%3D1 CONCLUSIONS: The IRT/IRT screening algorithm reduces the costs to laboratories and insurance companies but has more system failures. IRT/DNA offers other advantages, including fewer delayed diagnoses and lower out-of-pocket costs to families. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651226 Wed, 01 Feb 2012 05:00:00 +0100 5651226 http://www.medworm.com/index.php?rid=5651225&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2F338%3Frss%3D1 The number of births in the United States decreased by 3% between 2008 and 2009 to 4 130 665 births. The general fertility rate also declined 3% to 66.7 per 1000 women. The teenage birth rate fell 6% to 39.1 per 1000. Birth rates also declined for women 20 to 39 years and for all 5-year groups, but the rate for women 40 to 44 years continued to rise. The percentage of all births to unmarried women increased to 41.0% in 2009, up from 40.6% in 2008. In 2009, 32.9% of all births occurred by cesarean delivery, continuing its rise. The 2009 preterm birth rate declined for the third year in a row to 12.18%. The low-birth-weight rate was unchanged in 2009 at 8.16%. Both twin and triplet and higher order birth rates increased. The infant mortality rate was 6.42 infant deaths per 1000 live births i... PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651225 Wed, 01 Feb 2012 05:00:00 +0100 5651225 http://www.medworm.com/index.php?rid=5651224&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe333%3Frss%3D1 CONCLUSIONS: Heliox increases the effectiveness of NCPAP in the treatment of RDS in premature infants. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651224 Wed, 01 Feb 2012 05:00:00 +0100 5651224 http://www.medworm.com/index.php?rid=5651223&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2F330%3Frss%3D1 This article is intended to provide a comprehensive overview of the role of dietary methods for treatment of children with attention-deficit/hyperactivity disorder (ADHD) when pharmacotherapy has proven unsatisfactory or unacceptable. Results of recent research and controlled studies, based on a PubMed search, are emphasized and compared with earlier reports. The recent increase of interest in this form of therapy for ADHD, and especially in the use of omega supplements, significance of iron deficiency, and the avoidance of the "Western pattern" diet, make the discussion timely. Diets to reduce symptoms associated with ADHD include sugar-restricted, additive/preservative-free, oligoantigenic/elimination, and fatty acid supplements. Omega–3 supplement is the latest dietary treatment w... PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651223 Wed, 01 Feb 2012 05:00:00 +0100 5651223 http://www.medworm.com/index.php?rid=5651222&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe325%3Frss%3D1 CONCLUSIONS: We found no clinically significant association between process and outcome quality measures in the delivery of asthma-related care to children in a multicenter study. Although the quality of emergency department care does not predict successful discharge, other factors, such as outpatient care, may better predict outcomes. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651222 Wed, 01 Feb 2012 05:00:00 +0100 5651222 http://www.medworm.com/index.php?rid=5651221&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2F318%3Frss%3D1 CONCLUSIONS: In pediatric patients with IF, EL is a more effective alternative to HL. Adverse events include thrombotic events. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651221 Wed, 01 Feb 2012 05:00:00 +0100 5651221 http://www.medworm.com/index.php?rid=5651220&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe317%3Frss%3D1 CONCLUSIONS: Positive associations were observed for anorectal atresia, esophageal atresia, and omphalocele and maternal periconceptional asthma medication use, but not for other defects studied. It is possible that observed associations may be chance findings or may be a result of maternal asthma severity and related hypoxia rather than medication use. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651220 Wed, 01 Feb 2012 05:00:00 +0100 5651220 http://www.medworm.com/index.php?rid=5651219&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2F309%3Frss%3D1 CONCLUSIONS: With at least 50% of children experiencing sunburns before age 11 and again 3 years later, targeting children in pediatric offices and community settings regarding unprotected UV exposure may be a practical approach. Because periadolescence is a time of volatility with regard to sun behaviors, learning more about children who receive sunburns versus those who avoid them is a critical research task. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651219 Wed, 01 Feb 2012 05:00:00 +0100 5651219 http://www.medworm.com/index.php?rid=5651218&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe305%3Frss%3D1 CONCLUSIONS: These findings suggest that the presence of co-occurring psychiatric and neurodevelopmental conditions are associated with a change in ASD diagnosis. Questions remain as to whether changes in diagnosis of an ASD are due to true etiologic differences or shifts in diagnostic determination. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651218 Wed, 01 Feb 2012 05:00:00 +0100 5651218 http://www.medworm.com/index.php?rid=5651217&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2F299%3Frss%3D1 CONCLUSIONS: Sucrose with and without FT had pain-relieving effects even in preterm infants of <32 weeks of gestation having repeated pain exposures. These interventions remained effective during repeated heel sticks across time. FT was not as effective and cannot be recommended as a nonpharmacologic pain relief intervention for repeated pain exposure. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651217 Wed, 01 Feb 2012 05:00:00 +0100 5651217 http://www.medworm.com/index.php?rid=5651216&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe298%3Frss%3D1 CONCLUSIONS: Among infants <33 weeks’ gestation, NEC appears to present at mean age of 7 days in more mature infants, whereas onset of NEC is delayed to 32 days of age in smaller, lower GA infants. Further studies are required to understand the etiology of this disease process. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651216 Wed, 01 Feb 2012 05:00:00 +0100 5651216 http://www.medworm.com/index.php?rid=5651215&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe291%3Frss%3D1 CONCLUSIONS: IVIG treatment ≥10 days after illness onset achieves resolution of inflammation but was found to be insufficient for preventing CALs. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651215 Wed, 01 Feb 2012 05:00:00 +0100 5651215 http://www.medworm.com/index.php?rid=5651214&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2F290%3Frss%3D1 CONCLUSIONS: Carpooling is a common driving situation during which booster seat use is inconsistent. Social norms and self-efficacy are associated with booster seat use. Clinicians who care for children should increase efforts to convey the importance of using the size-appropriate restraint for every child on every trip. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651214 Wed, 01 Feb 2012 05:00:00 +0100 5651214 http://www.medworm.com/index.php?rid=5651213&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe285%3Frss%3D1 CONCLUSIONS: In preschool-aged children, 12-week treatment with montelukast, compared with placebo, did not reduce the incidence of URI. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651213 Wed, 01 Feb 2012 05:00:00 +0100 5651213 http://www.medworm.com/index.php?rid=5651212&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2F282%3Frss%3D1 CONCLUSIONS: Follow-up examinations by specialists affected the interpretation of trauma and detection of STIs in ~23% of pediatric patients undergoing sexual abuse assessments. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651212 Wed, 01 Feb 2012 05:00:00 +0100 5651212 http://www.medworm.com/index.php?rid=5651211&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe276%3Frss%3D1 CONCLUSIONS: Ten percent of children are reported to have a sleep problem at any given point during early childhood, and these problems persist in a significant minority of children throughout early development. Parent response to a single-item nonspecific sleep query may overlook relevant sleep behaviors and symptoms associated with clinical morbidity. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651211 Wed, 01 Feb 2012 05:00:00 +0100 5651211 http://www.medworm.com/index.php?rid=5651210&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2F275%3Frss%3D1 CONCLUSIONS: Pediatric hospitalization rates for drowning have decreased over the past 16 years. Our study provides national estimates of pediatric drowning hospitalization that can be used as benchmarks to target and assess prevention strategies. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651210 Wed, 01 Feb 2012 05:00:00 +0100 5651210 http://www.medworm.com/index.php?rid=5651209&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe269%3Frss%3D1 CONCLUSIONS: Although this trial does not statistically demonstrate the noninferiority of oral treatment compared with the sequential treatment, our study confirmed the results of previously published reports and therefore supports the use of an oral antibiotic treatment of primary episodes of acute pyelonephritis in infants and young children. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651209 Wed, 01 Feb 2012 05:00:00 +0100 5651209 http://www.medworm.com/index.php?rid=5651208&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2F265%3Frss%3D1 CONCLUSIONS: Societal priorities for young children—safety and school readiness—may be hindering children’s physical development. In designing environments that optimally promote children’s health and development, child advocates should think holistically about potential unintended consequences of policies. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651208 Wed, 01 Feb 2012 05:00:00 +0100 5651208 http://www.medworm.com/index.php?rid=5651207&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe262%3Frss%3D1 CONCLUSIONS: Moderate/severe TBI at an early age appears to be associated with lowered intellectual function and possibly behavior problems. A child’s environment influences cognitive and behavior function after TBI. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651207 Wed, 01 Feb 2012 05:00:00 +0100 5651207 http://www.medworm.com/index.php?rid=5651206&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2F256%3Frss%3D1 CONCLUSIONS: In a nationally representative sample, children with seizures were at increased risk for mental health, developmental, and physical comorbidities, increasing needs for care coordination and specialized services. Children with reported prior but not current seizures need further study to establish reasons for their higher than expected levels of reported functional limitations. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651206 Wed, 01 Feb 2012 05:00:00 +0100 5651206 http://www.medworm.com/index.php?rid=5651205&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2Fe254%3Frss%3D1 CONCLUSIONS: Results confirm a high risk of persisting deficits after severe TBI in early childhood. Children with less severe TBI appear to recover to function normally. Contrary to speculation about "growing into deficits," after protracted recovery to 30 months, young children make age-appropriate progress at least to 10 years postinsult. Environmental factors were found to contribute to adaptive and social/behavioral recovery. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651205 Wed, 01 Feb 2012 05:00:00 +0100 5651205 http://www.medworm.com/index.php?rid=5651204&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2F248%3Frss%3D1 CONCLUSIONS: ITP is unlikely after early childhood vaccines other than MMR. Because of the small number of exposed cases and potential confounding, the possible association of ITP with hepatitis A, varicella, and tetanus-diphtheria-acellular pertussis vaccines in older children requires further investigation. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651204 Wed, 01 Feb 2012 05:00:00 +0100 5651204 http://www.medworm.com/index.php?rid=5651203&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2F239%3Frss%3D1 CONCLUSIONS: Our study provides novel insights into the values that underpin citizens’ acceptance and discomfort with routine storage of NBS samples for research, and supports the need to develop well-designed methods of public education and civic discourse on the risks and benefits of the retention and secondary use of NBS samples. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651203 Wed, 01 Feb 2012 05:00:00 +0100 5651203 http://www.medworm.com/index.php?rid=5651202&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2F231%3Frss%3D1 CONCLUSIONS: Our results show that the general public surveyed here was supportive of NBS and residual sample retention and research use. However, there was a clear preference for an informed permission process for parents regarding these activities. Education about NBS was associated with a higher level of support and may be important to maintain public trust in these important programs. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651202 Wed, 01 Feb 2012 05:00:00 +0100 5651202 http://www.medworm.com/index.php?rid=5651201&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2F222%3Frss%3D1 CONCLUSIONS: Variable pediatrician attitudes and cardiac screening practices reflect the limited evidence base and conflicting guidelines regarding cardiac screening. Barriers to identifying cardiac disorders influence practice. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651201 Wed, 01 Feb 2012 05:00:00 +0100 5651201 http://www.medworm.com/index.php?rid=5651200&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2F213%3Frss%3D1 CONCLUSIONS: HepA coverage was low among most adolescents in the United States in 2009 leaving a large population susceptible to hepatitis A infection maturing into adulthood. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651200 Wed, 01 Feb 2012 05:00:00 +0100 5651200 http://www.medworm.com/index.php?rid=5651199&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2F205%3Frss%3D1 CONCLUSIONS: Drinking frequency provides an empirically supported brief screen to efficiently identify youth with alcohol-related problems. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651199 Wed, 01 Feb 2012 05:00:00 +0100 5651199 http://www.medworm.com/index.php?rid=5651198&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Ffull%2F129%2F2%2F201%3Frss%3D1 (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651198 Wed, 01 Feb 2012 05:00:00 +0100 5651198 http://www.medworm.com/index.php?rid=5651197&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX38%3Frss%3D1 Several studies have focused on birth weight heritability, reporting results that range between 40% and 80%. Few studies have focused on the process of weight gain and were mainly based on heterogeneous samples of infants. The present work looks at a uniform set of healthy preterm newborn twins. The resulting high heritability estimate could suggest using the inclusion criteria to identify genes that regulate postnatal weight gain or failure. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651197 Wed, 01 Feb 2012 05:00:00 +0100 5651197 http://www.medworm.com/index.php?rid=5651196&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX37%3Frss%3D1 Previous observational studies and randomized trials have reported an association between the use of epidural analgesia for pain relief in labor and intrapartum maternal fever. Studies have also reported an increase in adverse neonatal outcomes with intrapartum maternal fever. Among low-risk women receiving epidural analgesia, intrapartum maternal temperature >99.5°F was associated with adverse neonatal outcomes, with the rate of adverse outcomes increasing directly with maximum maternal temperature. Without temperature elevation, epidural use was not associated with adverse neonatal outcomes. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651196 Wed, 01 Feb 2012 05:00:00 +0100 5651196 http://www.medworm.com/index.php?rid=5651195&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX36%3Frss%3D1 Eating disorders are characterized by preoccupation with weight and shape, which is manifested by a refusal to maintain a normal weight. An exact determination of expected body weight (EBW) is critical for diagnosis and clinical management of these disorders. The McLaren and Moore methods present with several limitations when calculating EBW for adolescents with eating disorders. A commonly agreed upon method for EBW calculation such as the BMI percentile method is recommended for clinical and research purposes. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651195 Wed, 01 Feb 2012 05:00:00 +0100 5651195 http://www.medworm.com/index.php?rid=5651194&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX35%3Frss%3D1 Macroglossia is a clinical feature of several disorders and a common reason for additional diagnostic investigations during infancy. Limited research has been done on the evaluation of macroglossia when other features are not suggestive of Beckwith-Wiedemann syndrome. All patients with apparently isolated macroglossia should have at least initial evaluation with abdominal ultrasounds and molecular studies for Beckwith-Wiedemann syndrome before a final diagnosis is given. Other common diagnoses included isolated macroglossia, chromosomal abnormalities, hypothyroidism, and mucopolysaccharidoses. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651194 Wed, 01 Feb 2012 05:00:00 +0100 5651194 http://www.medworm.com/index.php?rid=5651193&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX34%3Frss%3D1 Pertussis is a poorly controlled vaccine-preventable disease. Verifying outbreaks is challenging owing to nonspecific clinical presentations and imperfect diagnostic tests. Exclusive reliance on highly sensitive polymerase chain reaction has been associated with pseudo-outbreaks. Contamination of specimens with vaccine derived Bordetella pertussis DNA from pediatric clinic surfaces likely resulted in misdiagnoses. Standard practices, liquid transport medium, and lack of polymerase chain reaction cutoffs for discerning weakly positive (contaminant) DNA are contributory, but modifiable factors. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651193 Wed, 01 Feb 2012 05:00:00 +0100 5651193 http://www.medworm.com/index.php?rid=5651192&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX33%3Frss%3D1 This study of children with cerebral palsy and their mothers did not confirm previously reported candidate gene associations. Prothrombin gene mutation was associated with hemiplegia in children born at term to mothers with a reported infection during pregnancy. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651192 Wed, 01 Feb 2012 05:00:00 +0100 5651192 http://www.medworm.com/index.php?rid=5651191&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX32%3Frss%3D1 Refugee children arriving in the United States have had higher rates of elevated blood lead levels than US-born children. The Centers for Disease Control and Prevention recommends blood lead screening of all refugee children within 3 months after their arrival in the United States. This is the first investigation we are aware of to examine and identify risk factors for lead poisoning among US-bound refugee children living in camps overseas, before their arrival in the United States. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651191 Wed, 01 Feb 2012 05:00:00 +0100 5651191 http://www.medworm.com/index.php?rid=5651190&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX31%3Frss%3D1 Recent studies have called into question the benefit of perioperative corticosteroids in children undergoing heart surgery, but have been limited by small sample size, the lack of placebo control, and the grouping of various steroid regimens together in analysis. We evaluated outcomes across methylprednisolone regimens versus no steroids in a large cohort of neonates and found no mortality or length-of-stay benefit associated with any regimen, and a higher risk of infection in certain subgroups. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651190 Wed, 01 Feb 2012 05:00:00 +0100 5651190 http://www.medworm.com/index.php?rid=5651189&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX30%3Frss%3D1 Recommendations in pediatrics call for general developmental screening of young children; however, research suggests social-emotional development, in particular, is important as an initial indicator of general well-being versus risk, and may warrant inclusion in screening protocols. Via a social-emotional screening program, significant percentages of children can be identified as being at risk for social-emotional problems, and colocation of an early childhood psychologist promotes the ability to effectively address young children’s social-emotional development within their medical home. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651189 Wed, 01 Feb 2012 05:00:00 +0100 5651189 http://www.medworm.com/index.php?rid=5651188&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX29%3Frss%3D1 Previous analyses have suggested that center volume is associated with outcome in children undergoing heart surgery. There are limited data regarding factors that may mediate this volume–outcome relationship. A multicenter analysis of 35 776 children revealed that the higher mortality observed at lower volume centers may be related to a higher rate of mortality in those with postoperative complications, rather than a higher rate of complications alone. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651188 Wed, 01 Feb 2012 05:00:00 +0100 5651188 http://www.medworm.com/index.php?rid=5651187&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX28%3Frss%3D1 Chronic wet cough is a common symptom well recognized by pediatricians. Protracted bacterial bronchitis is defined as more than 4 weeks of wet cough that responds to antibiotic treatment. Diagnosis of protracted bacterial bronchitis is not readily accepted by pediatricians Children with chronic wet cough often have bronchitis, which is evident during bronchoscopy. Purulent bronchial secretions suggest the presence of bacterial infection. Children with chronic wet cough frequently have a bacterial infection of the lower airway. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651187 Wed, 01 Feb 2012 05:00:00 +0100 5651187 http://www.medworm.com/index.php?rid=5651186&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX27%3Frss%3D1 High-grade vesicoureteral reflux is a risk factor for impaired renal function. Diagnosis by voiding cystourethrography is invasive and highly uncomfortable. As only a minority of children show high-grade vesicoureteral reflux, this exposes the majority to unnecessary distress. This case-control study proved that high-grade vesicoureteral reflux is identifiable with high sensitivity using urinary proteome analysis, based on capillary electrophoresis coupled to mass spectrometry in a cohort suspected of having vesicoureteral reflux, thus sparing the majority of children from invasive diagnostics. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651186 Wed, 01 Feb 2012 05:00:00 +0100 5651186 http://www.medworm.com/index.php?rid=5651185&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX26%3Frss%3D1 Registries have been established in a number of countries to monitor the health of patients with cystic fibrosis. Few international comparisons have been made between registries. International data registry comparisons may be useful for informing best practice and benchmarking. Registry comparisons are feasible but are limited by factors such as nonstandardization of data collection. Lung function was lower in Australian children with cystic fibrosis compared with their US counterparts after adjusting for the benefits of diagnosis after newborn screening. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651185 Wed, 01 Feb 2012 05:00:00 +0100 5651185 http://www.medworm.com/index.php?rid=5651184&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX25%3Frss%3D1 This study contributes by offering a comparison of both costs, assessed comprehensively, and the consequences associated with the 2 most popular screening methodologies, immunoreactive trypsinogen/immunoreactive trypsinogen and immunoreactive trypsinogen/DNA, by using a decision-tree framework allowing variation in the model parameters. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651184 Wed, 01 Feb 2012 05:00:00 +0100 5651184 http://www.medworm.com/index.php?rid=5651183&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX24%3Frss%3D1 Nasal continuous positive airway pressure (NCPAP) is a noninvasive ventilatory support that may reduce the need for mechanical ventilation in preterm infants with respiratory distress syndrome. Heliox, a helium-oxygen mixture, has shown positive effects, especially in obstructive diseases. NCPAP with heliox reduces the need for mechanical ventilation in preterm infants with respiratory distress syndrome in comparison with NCPAP with medical air. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651183 Wed, 01 Feb 2012 05:00:00 +0100 5651183 http://www.medworm.com/index.php?rid=5651182&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX23%3Frss%3D1 Studies of the association between process and outcome measures of the quality of acute asthma care for children have been mixed. These studies are limited by small, single-institution settings or by examining the association at the aggregate level. This first multicenter analysis of the process-outcome association in acute asthma care for children revealed no association. Because the validity of process measures depends on association with outcomes, further study is needed before implementing existing process measures as performance metrics. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651182 Wed, 01 Feb 2012 05:00:00 +0100 5651182 http://www.medworm.com/index.php?rid=5651181&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX22%3Frss%3D1 Asthma is a common obstructive pulmonary disease experienced during pregnancy. Clinical guidelines recommend women with asthma maintain asthma medication use during pregnancy. Epidemiologic studies suggest an association between several types of defects and asthma or asthma medication use during pregnancy. Data from a large, population-based, multicenter, case-control study was used. This provides the opportunity to study specific birth defects with minimal heterogeneity in case groups, as well as control for a variety of potential confounders. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651181 Wed, 01 Feb 2012 05:00:00 +0100 5651181 http://www.medworm.com/index.php?rid=5651180&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX21%3Frss%3D1 Mixed prevalence rates of co-occurring psychiatric and neurodevelopmental conditions have been reported in children diagnosed with an autism spectrum disorder (ASD). ASD diagnoses remain fairly stable within a continuum, but some do not meet criteria for an ASD diagnosis years after initial diagnosis. Co-occurring neurodevelopmental and psychiatric conditions may explain, in part, why the diagnosis of an ASD may change with age. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651180 Wed, 01 Feb 2012 05:00:00 +0100 5651180 http://www.medworm.com/index.php?rid=5651179&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX20%3Frss%3D1 Necrotizing enterocolitis (NEC) can present within the first week of life in term infants. In preterm infants, NEC usually appears after commencement of feeds and can occur between 2 and 3 weeks of life. Among infants <33 weeks’ gestation, NEC appears to occur at mean age of 7 days in more mature infants, whereas onset of NEC is delayed to 32 days of age in smaller, lower gestational age infants. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651179 Wed, 01 Feb 2012 05:00:00 +0100 5651179 http://www.medworm.com/index.php?rid=5651178&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX19%3Frss%3D1 The effectiveness of intravenous immunoglobulin treatment of patients with Kawasaki disease within 9 days of illness has been established. However, the effectiveness of such treatment ≥10 days after illness onset has not yet been clarified. Intravenous immunoglobulin treatment ≥10 days after illness onset was observed to be effective for achieving inflammation resolution. Patients who are strongly suspected to have Kawasaki disease and demonstrate ongoing inflammation should therefore be treated as soon as possible. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651178 Wed, 01 Feb 2012 05:00:00 +0100 5651178 http://www.medworm.com/index.php?rid=5651177&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX18%3Frss%3D1 Upper respiratory tract infections (URIs) are very common in children. Currently, there are no effective preventive measures for URI. There are no studies on the effect of montelukast for prevention of URI. In a randomized, double-blind, placebo-controlled study of preschool-aged children, 12-week prophylactic treatment with montelukast did not reduce the incidence of URI. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651177 Wed, 01 Feb 2012 05:00:00 +0100 5651177 http://www.medworm.com/index.php?rid=5651176&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX17%3Frss%3D1 Sleep problems are common during childhood, but screening for sleep problems in the clinic setting is often cursory. Moreover, there are few longitudinal studies examining the prevalence and persistence of sleep problems in young children. Patterns of sleep problems vary across early development, but sleep problems arising in infancy persist in 21% of children through 36 months of age. Parent response to a nonspecific query about sleep problems may overlook relevant sleep symptoms and behaviors. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651176 Wed, 01 Feb 2012 05:00:00 +0100 5651176 http://www.medworm.com/index.php?rid=5651175&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX16%3Frss%3D1 The standard initial management for infants and children with acute pyelonephritis is intravenous antibiotic treatment. Our results support the use of an oral cefixime treatment of initial episodes of acute pyelonephritis involving a gram-negative bacteria strain in children aged 1 month to 3 years who are without urological abnormalities and without clinical hemodynamic impairment. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651175 Wed, 01 Feb 2012 05:00:00 +0100 5651175 http://www.medworm.com/index.php?rid=5651174&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX15%3Frss%3D1 Traumatic brain injury in school-aged children is associated with intellectual, behavioral, and social deficits. Research into outcomes of children injured before 3 years of age is limited despite data suggesting a high incidence of injury in this age group. Results show that a moderate to severe traumatic brain injury before 3 years of age is associated with lowered cognitive function. Furthermore, this study highlights the link between social disadvantage and poor outcomes after traumatic brain injury in early childhood. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651174 Wed, 01 Feb 2012 05:00:00 +0100 5651174 http://www.medworm.com/index.php?rid=5651173&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX14%3Frss%3D1 This study follows survivors of very early traumatic brain injury into adolescence. Results indicate that severe injury is associated with poorest outcome, but after 3 years, the gap between children with severe traumatic brain injury and peers stabilizes. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651173 Wed, 01 Feb 2012 05:00:00 +0100 5651173 http://www.medworm.com/index.php?rid=5651172&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX13%3Frss%3D1 Childhood UV light exposures, specifically sunburns, have been shown to be associated with melanoma development later in life. To date, most studies in this age group have been cross sectional in nature. This is the first prospective study of sunburn and sun behaviors in this age group. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651172 Wed, 01 Feb 2012 05:00:00 +0100 5651172 http://www.medworm.com/index.php?rid=5651171&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX12%3Frss%3D1 Preterm infants are exposed to inadequately managed painful procedures during their NICU stay, which can lead to altered pain responses. Nonpharmacologic approaches are established for the treatment of single painful procedures, but evidence for their effectiveness across time is lacking. Oral sucrose with or without the added technique of facilitated tucking has a pain-relieving effect even in extremely premature infants undergoing repeated pain exposures; facilitated tucking alone seems to be less effective for repeated pain exposures over time. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651171 Wed, 01 Feb 2012 05:00:00 +0100 5651171 http://www.medworm.com/index.php?rid=5651170&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX11%3Frss%3D1 Booster seat use improves seat belt fit and reduces risk of injury for children <57 in tall. Booster seat use decreases between ages 4 and 8 years. Children observed riding with other children frequently do not use booster seats. In this national survey of parents, we found that a majority of parents of 4- to 8-year-old children carpool, and when they carpool booster seat use is inconsistent. Social norms and self-efficacy appear to influence booster seat use when carpooling. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651170 Wed, 01 Feb 2012 05:00:00 +0100 5651170 http://www.medworm.com/index.php?rid=5651169&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX10%3Frss%3D1 Although follow-up examinations are recommended for suspected victims of sexual abuse or assault, little is known about the potential benefits of a second examination with regard to diagnosing trauma or sexually transmitted infections. In ~23% of pediatric patients evaluated for sexual abuse or assault, a second examination by a specialist changed the interpretation of trauma likelihood or results in the detection of a sexually transmitted infection. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651169 Wed, 01 Feb 2012 05:00:00 +0100 5651169 http://www.medworm.com/index.php?rid=5651168&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX9%3Frss%3D1 This study provides benchmarks that can be used for state and regional comparisons and monitoring of injury prevention efforts. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651168 Wed, 01 Feb 2012 05:00:00 +0100 5651168 http://www.medworm.com/index.php?rid=5651167&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX8%3Frss%3D1 Three-fourths of US preschool-age children are in child care; many are not achieving recommended levels of physical activity. Daily physical activity is essential for motor and socioemotional development and for the prevention of obesity. Little is known about physical-activity barriers in child care. Injury and school-readiness concerns may inhibit children’s physical activity in child care. Fixed playground equipment that meets licensing codes is unchallenging and uninteresting to children. Centers may cut time and space for gross motor play to address concerns about school readiness. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651167 Wed, 01 Feb 2012 05:00:00 +0100 5651167 http://www.medworm.com/index.php?rid=5651166&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX7%3Frss%3D1 Epilepsy/seizure disorder is known to be associated with a range of mental health and neurodevelopmental comorbidities, based on clinical studies, and on population studies largely conducted outside the United States. In a nationally representative sample of US children, estimated prevalence of reported lifetime epilepsy/seizure disorder was 1%, and of current epilepsy/seizure disorder was 6.3/1000. Developmental, mental health, and physical comorbidities are common, warranting enhanced surveillance, and an integrated service approach. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651166 Wed, 01 Feb 2012 05:00:00 +0100 5651166 http://www.medworm.com/index.php?rid=5651165&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX6%3Frss%3D1 This study found no increased risk of ITP after vaccines other than MMR in young children, confirmed an association of ITP with MMR, and also found that ITP may occur after certain other vaccines in older children. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651165 Wed, 01 Feb 2012 05:00:00 +0100 5651165 http://www.medworm.com/index.php?rid=5651164&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX5%3Frss%3D1 Newborn screening (NBS) programs may store bloodspot samples and use them for secondary purposes, such as research. Recent public controversies and lawsuits over storage and secondary uses underscore the need to engage the public on these issues. This public engagement study identifies values underlying citizens’ acceptance of and discomfort with research from NBS samples. Well-designed methods of public education and civic discourse on the risks and benefits of storage and secondary uses of NBS samples are required. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651164 Wed, 01 Feb 2012 05:00:00 +0100 5651164 http://www.medworm.com/index.php?rid=5651163&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX4%3Frss%3D1 This study offers a detailed analysis of public attitudes regarding bloodspot retention and use for biomedical research. The results also offer insights on how education regarding this practice influences support for newborn screening and residual bloodspot use. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651163 Wed, 01 Feb 2012 05:00:00 +0100 5651163 http://www.medworm.com/index.php?rid=5651162&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX3%3Frss%3D1 We present results from a national sample of pediatricians regarding current attitudes, barriers, and practices for cardiac screening in youth with attention-deficit/hyperactivity disorder before prescribing stimulants. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651162 Wed, 01 Feb 2012 05:00:00 +0100 5651162 http://www.medworm.com/index.php?rid=5651161&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX2%3Frss%3D1 Hepatitis A infection causes severe disease among adolescents and adults. Hepatitis A vaccination (HepA) is recommended universally at 1 year, with vaccination through 18 years based on risk or desire for protection. This is the first study to evaluate adolescent HepA coverage in the United States using provider-reported vaccination data. HepA coverage was low among adolescents, leaving a large population susceptible to hepatitis A infection maturing into adulthood. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651161 Wed, 01 Feb 2012 05:00:00 +0100 5651161 http://www.medworm.com/index.php?rid=5651160&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F2%2FX1%3Frss%3D1 The American Academy of Pediatrics recommends routine alcohol screening for all adolescents. Problem-based substance use screens for adolescents exist, but have limitations. A consumption-based alcohol screen could provide an empirically validated, very brief method to screen youth for alcohol-related problems. National sample data indicate that frequency of alcohol use has high sensitivity and specificity in identifying youth with alcohol-related problems. A range of age-specific frequency cut scores perform well; specific cut points can be selected based on the screening context. (Read the full article) (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651160 Wed, 01 Feb 2012 05:00:00 +0100 5651160 http://www.medworm.com/index.php?rid=5651159&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Ffull%2F129%2F2%2FD1%3Frss%3D1 (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5651159 Wed, 01 Feb 2012 05:00:00 +0100 5651159 http://www.medworm.com/index.php?rid=5612018&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2Fe199%3Frss%3D1 We report a human herpesvirus-8 (HHV-8)-infected child, born to consanguineous Comorian parents, who displayed isolated MCD in the absence of any known immunodeficiency. We also systematically review the clinical features of the 32 children previously reported with isolated and unexplained MCD. The characteristics of this patient and the geographic areas of origin of most previous cases suggest that pediatric MCD is associated with HHV-8 infection. Moreover, as previously suggested for Kaposi sarcoma, MCD in childhood may result from inborn errors of immunity to HHV-8 infection. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5612018 Fri, 30 Dec 2011 05:00:00 +0100 5612018 http://www.medworm.com/index.php?rid=5553895&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2Fe247%3Frss%3D1 Additional strategies are needed to protect children from vaccine-preventable diseases. In particular, very young infants, as well as children who are immunocompromised, are at especially high risk for developing the serious consequences of vaccine-preventable diseases and cannot be immunized completely. There is some evidence that children who become infected with these diseases are exposed to pathogens through household contacts, particularly from parents or other close family contacts. Such infections likely are attributable to adults who are not fully protected from these diseases, either because their immunity to vaccine-preventable diseases has waned over time or because they have not received a vaccine. There are many challenges that have added to low adult immunization rates in the... PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553895 Fri, 30 Dec 2011 05:00:00 +0100 5553895 http://www.medworm.com/index.php?rid=5553894&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2Fe232%3Frss%3D1 Advances in fields of inquiry as diverse as neuroscience, molecular biology, genomics, developmental psychology, epidemiology, sociology, and economics are catalyzing an important paradigm shift in our understanding of health and disease across the lifespan. This converging, multidisciplinary science of human development has profound implications for our ability to enhance the life prospects of children and to strengthen the social and economic fabric of society. Drawing on these multiple streams of investigation, this report presents an ecobiodevelopmental framework that illustrates how early experiences and environmental influences can leave a lasting signature on the genetic predispositions that affect emerging brain architecture and long-term health. The report also examines extensive ... PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553894 Fri, 30 Dec 2011 05:00:00 +0100 5553894 http://www.medworm.com/index.php?rid=5553893&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2Fe224%3Frss%3D1 Advances in a wide range of biological, behavioral, and social sciences are expanding our understanding of how early environmental influences (the ecology) and genetic predispositions (the biologic program) affect learning capacities, adaptive behaviors, lifelong physical and mental health, and adult productivity. A supporting technical report from the American Academy of Pediatrics (AAP) presents an integrated ecobiodevelopmental framework to assist in translating these dramatic advances in developmental science into improved health across the life span. Pediatricians are now armed with new information about the adverse effects of toxic stress on brain development, as well as a deeper understanding of the early life origins of many adult diseases. As trusted authorities in child health an... PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553893 Fri, 30 Dec 2011 05:00:00 +0100 5553893 http://www.medworm.com/index.php?rid=5553892&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2Fe214%3Frss%3D1 Children who join families through the process of adoption often have multiple health care needs. After placement in an adoptive home, it is essential that these children have a timely comprehensive health evaluation. This evaluation should include a review of all available medical records and a complete physical examination. Evaluation should also include diagnostic testing based on the findings from the history and physical examination as well as the risks presented by the child’s previous living conditions. Age-appropriate screens should be performed, including, for example, newborn screening panels, hearing, vision, dental, and formal behavioral/developmental screens. The comprehensive assessment can occur at the time of the initial visit to the physician after adoptive placement... PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553892 Fri, 30 Dec 2011 05:00:00 +0100 5553892 http://www.medworm.com/index.php?rid=5553891&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2Fe204%3Frss%3D1 Play is essential to the social, emotional, cognitive, and physical well-being of children beginning in early childhood. It is a natural tool for children to develop resiliency as they learn to cooperate, overcome challenges, and negotiate with others. Play also allows children to be creative. It provides time for parents to be fully engaged with their children, to bond with their children, and to see the world from the perspective of their child. However, children who live in poverty often face socioeconomic obstacles that impede their rights to have playtime, thus affecting their healthy social-emotional development. For children who are underresourced to reach their highest potential, it is essential that parents, educators, and pediatricians recognize the importance of lifelong benefit... PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553891 Fri, 30 Dec 2011 05:00:00 +0100 5553891 http://www.medworm.com/index.php?rid=5553890&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2Fe199%3Frss%3D1 We report a human herpesvirus-8 (HHV-8)-infected child, born to consanguineous Comorian parents, who displayed isolated MCD in the absence of any known immunodeficiency. We also systematically review the clinical features of the 32 children previously reported with isolated and unexplained MCD. The characteristics of this patient and the geographic areas of origin of most previous cases suggest that pediatric MCD is associated with HHV-8 infection. Moreover, as previously suggested for Kaposi sarcoma, MCD in childhood may result from inborn errors of immunity to HHV-8 infection. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553890 Fri, 30 Dec 2011 05:00:00 +0100 5553890 http://www.medworm.com/index.php?rid=5553889&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2Fe195%3Frss%3D1 A 10-year-old girl presented with diabetic ketoacidosis, shock, and severe abdominal pain. She was found to have acute pancreatitis and acute kidney injury after shock resuscitation and severe persistent hypertriglyceridemia. The severe hypertriglyceridemia was treated with 1 course of plasmapheresis, which corrected the triglyceride level and was temporally associated with improvement of the abdominal pain and renal dysfunction. Diabetes is known to contribute to an elevated triglyceride level, especially in the setting of an underlying lipid disorder. However, no such disorders were found in this patient. To the best of our knowledge, this is the first report of a pediatric patient presenting with the triad of severe hypertriglyceridemia, diabetic ketoacidosis, and pancreatitis treated s... PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553889 Fri, 30 Dec 2011 05:00:00 +0100 5553889 http://www.medworm.com/index.php?rid=5553888&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2F193%3Frss%3D1 A variety of triggers can induce common pediatric allergic diseases which include asthma, allergic rhinitis, atopic dermatitis, food allergy, and anaphylaxis. Allergy testing serves to confirm an allergic trigger suspected on the basis of history. Tests for allergen-specific immunoglobulin E (IgE) are performed by in vitro assays or skin tests. The tests are excellent for identifying a sensitized state in which allergen-specific IgE is present, and may identify triggers to be eliminated and help guide immunotherapy treatment. However, a positive test result does not always equate with clinical allergy. Newer enzymatic assays based on anti-IgE antibodies have supplanted the radioallergosorbent test (RAST). This clinical report focuses on allergen-specific IgE testing, emphasizing that the m... PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553888 Fri, 30 Dec 2011 05:00:00 +0100 5553888 http://www.medworm.com/index.php?rid=5553887&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2F190%3Frss%3D1 Incorporation of pulse oximetry to the assessment of the newborn infant can enhance detection of critical congenital heart disease (CCHD). Recently, the Secretary of Health and Human Services (HHS) recommended that screening for CCHD be added to the uniform screening panel. The American Academy of Pediatrics (AAP) has been a strong advocate of early detection of CCHD and fully supports the decision of the Secretary of HHS. The AAP has published strategies for the implementation of pulse oximetry screening, which addressed critical issues such as necessary equipment, personnel, and training, and also provided specific recommendations for assessment of saturation by using pulse oximetry as well as appropriate management of a positive screening result. The AAP is committed to the safe and eff... PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553887 Fri, 30 Dec 2011 05:00:00 +0100 5553887 http://www.medworm.com/index.php?rid=5553886&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2Fe189%3Frss%3D1 We report the case of a child who developed severe EBV-related PTLD after haplo-HSCT from his mother. Despite receiving the anti-CD20 monoclonal antibody, the patient presented with intestinal obstruction due to huge abdominal lymphadenopathy, hematemesis, and nodulary pulmonary lesions. Histology showed that the lesions were due to CD20–/CD19+ large neoplastic B cells. The patient underwent double intestinal resection with partial abdominal lymphadenectomy and then received 3 monthly doses of donor-derived unmanipulated mononuclear cells. The initial dose of CD3+ cells was 3 105/kg recipient body weight. The 2 additional doses consisted of 5 105 CD3+ cells/kg. No sign or symptom attributable to graft-versus-host disease was observed, and the patient completely cleared EBV-... PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553886 Fri, 30 Dec 2011 05:00:00 +0100 5553886 http://www.medworm.com/index.php?rid=5553885&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2F185%3Frss%3D1 The optimal health of all children is best achieved with access to appropriate and comprehensive health care benefits. This policy statement outlines and defines the recommended set of health insurance benefits for children through age 26. The American Academy of Pediatrics developed a set of recommendations concerning preventive care services for children, adolescents, and young adults. These recommendations are compiled in the publication Bright Futures: Guidelines for Health Supervision of Infants, Children, and Adolescents, third edition. The Bright Futures recommendations were referenced as a standard for access and design of age-appropriate health insurance benefits for infants, children, adolescents, and young adults in the Patient Protection and Affordable Care Act of 2010 (Pub L N... PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553885 Fri, 30 Dec 2011 05:00:00 +0100 5553885 http://www.medworm.com/index.php?rid=5553884&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2Fe183%3Frss%3D1 This report suggests that children found with a deletion involving the FOXP2 region should be evaluated for CAS and that analysis of the FOXP2 gene including array comparative genomic hybridization should be considered in selected patients with CAS. Mosaic deletions in this area may also be considered as causative of CAS. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553884 Fri, 30 Dec 2011 05:00:00 +0100 5553884 http://www.medworm.com/index.php?rid=5553883&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2Fe179%3Frss%3D1 Parotitis is a common condition seen in the pediatric population, usually as an isolated occurrence associated with viral or bacterial infection. The differential diagnosis expands when recurrent parotitis is encountered. One etiology is primary pediatric Sjögren syndrome (SS), an autoimmune condition typically associated with dryness of the eyes and mouth in adults. Pediatric patients often present with isolated recurrent bilateral parotitis, however, and we describe 4 such cases in children aged 9 to 17 years at presentation. Despite lack of ocular complaints, 3 of these patients had ocular findings on ophthalmologic exam. Our patients also exhibited classic laboratory abnormalities, including positive antinuclear antibody, SS A, and SS B antibodies; presence of rheumatoid factor; a... PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553883 Fri, 30 Dec 2011 05:00:00 +0100 5553883 http://www.medworm.com/index.php?rid=5553882&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2Fe174%3Frss%3D1 Long-term growth and developmental data are presented for the smallest and third smallest surviving newborns in the world literature to 5 and 20 years of age, respectively. Both patients exhibited normal motor and language development. Although head circumference for both newborns demonstrated catchup growth, significant differences in height and weight growth velocities persisted. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553882 Fri, 30 Dec 2011 05:00:00 +0100 5553882 http://www.medworm.com/index.php?rid=5553881&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Ffull%2F129%2F1%2F170%3Frss%3D1 (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553881 Fri, 30 Dec 2011 05:00:00 +0100 5553881 http://www.medworm.com/index.php?rid=5553880&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Ffull%2F129%2F1%2F168%3Frss%3D1 (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553880 Fri, 30 Dec 2011 05:00:00 +0100 5553880 http://www.medworm.com/index.php?rid=5553879&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2Fe165%3Frss%3D1 Conclusions: Quality improvement efforts were associated with sustained reductions in NI, bronchopulmonary dysplasia, antibiotic use, central line use, and ventilator days. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553879 Fri, 30 Dec 2011 05:00:00 +0100 5553879 http://www.medworm.com/index.php?rid=5553878&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Ffull%2F129%2F1%2F163%3Frss%3D1 (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553878 Fri, 30 Dec 2011 05:00:00 +0100 5553878 http://www.medworm.com/index.php?rid=5553877&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2Fe157%3Frss%3D1 Conclusions: Review of nursery and audiology records successfully established most quality indicators for the UNHS programs we studied. Feedback of quality indicators identified multiple improvement opportunities and facilitated endorsement of immediate system changes. This study demonstrates a practical and data-driven approach to quality improvement that can be used by any UNHS program. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553877 Fri, 30 Dec 2011 05:00:00 +0100 5553877 http://www.medworm.com/index.php?rid=5553876&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2F153%3Frss%3D1 Translational research is expanding and has become a focus of National Research funding agencies, touted as the primary avenue to improve health care practice. The use of human tissues for research on disease etiology is a pillar of translational research, particularly with innovations in research technologies to investigate the building blocks of disease. In pediatrics, translational research using human tissues has been hindered by the many practical and ethical considerations associated with tissue procurement from children and also by a limited population base for study, by the increasing complexities in conducting clinical research, and by a lack of dedicated child-health research funding. Given these obstacles, pediatric translational research can be enhanced by developing strategic ... PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553876 Fri, 30 Dec 2011 05:00:00 +0100 5553876 http://www.medworm.com/index.php?rid=5553875&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2Fe148%3Frss%3D1 Conclusions: Despite their severe disabilities and symptoms, most SMARD1 patients are well integrated into their home environment and two thirds of them are able to attend kindergarten or school. This information will help to counsel parents at the time of disease manifestation. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553875 Fri, 30 Dec 2011 05:00:00 +0100 5553875 http://www.medworm.com/index.php?rid=5553874&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2Fe142%3Frss%3D1 Conclusions: Aluminum reference ranges provided by laboratories are widely divergent, may not represent "normal" ranges of a healthy population, especially children, and thus it is difficult to interpret serum or urine aluminum ranges clinically. Further studies of aluminum in children are warranted and should be considered as part of the Centers for Disease Control and Prevention Biomonitoring Project. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553874 Fri, 30 Dec 2011 05:00:00 +0100 5553874 http://www.medworm.com/index.php?rid=5553873&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2F141%3Frss%3D1 CONCLUSIONS: Interventions to achieve cessation among parents, for the sake of the children, provide a worthwhile addition to the arsenal of cessation approaches, and can help protect vulnerable children from harm due to tobacco smoke exposure. However, most parents do not quit, and additional strategies to protect children are needed. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553873 Fri, 30 Dec 2011 05:00:00 +0100 5553873 http://www.medworm.com/index.php?rid=5553872&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2Fe134%3Frss%3D1 Conclusions: HCA is associated with a significantly reduced risk of acquiring LOS, both with CoNS and other bacteria. Perinatal inflammation may enhance the functional maturation of the preterm immune system and provide protection against LOS in high-risk preterm infants. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553872 Fri, 30 Dec 2011 05:00:00 +0100 5553872 http://www.medworm.com/index.php?rid=5553871&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2F132%3Frss%3D1 Conclusions: Poor quality of the early maternal–child relationship was associated with a higher prevalence of adolescent obesity. Interventions aimed at improving the quality of maternal–child interactions should consider assessing effects on children’s weight and examining potential mechanisms involving stress response and emotion regulation. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553871 Fri, 30 Dec 2011 05:00:00 +0100 5553871 http://www.medworm.com/index.php?rid=5553870&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2Fe128%3Frss%3D1 Conclusions: Although some children did not manifest all expected responses, no child with an accidental fracture was asymptomatic. Delay in seeking medical care was associated with more subtle signs of injury; however, delays identified in minority patients are unexplained. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553870 Fri, 30 Dec 2011 05:00:00 +0100 5553870 http://www.medworm.com/index.php?rid=5553869&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2F124%3Frss%3D1 Conclusions: In the modern era of neonatal management, male infants still have higher mortality and poorer long-term neurologic outcome. Gender differences for mortality and long-term neurologic outcome appear to lose significance at 27 weeks gestation. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553869 Fri, 30 Dec 2011 05:00:00 +0100 5553869 http://www.medworm.com/index.php?rid=5553868&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2Fe120%3Frss%3D1 Conclusions: The 2 prognostic models for stillbirth and neonatal death in very preterm Dutch infants showed good performance, suggesting their use in clinical practice in the Netherlands and possibly other Western countries. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553868 Fri, 30 Dec 2011 05:00:00 +0100 5553868 http://www.medworm.com/index.php?rid=5553867&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2F116%3Frss%3D1 Conclusions: Prophylactic oral administration of bLF reduces the incidence of IFI in preterm VLBW neonates. No effect is seen on colonization. The protective effect on IFI is likely due to limitation of ability of fungal colonies to progress toward invasion and systemic disease in colonized infants. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553867 Fri, 30 Dec 2011 05:00:00 +0100 5553867 http://www.medworm.com/index.php?rid=5553866&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2Fe113%3Frss%3D1 Conclusions Compared with the data from the United States, more children in Japan visit community physicians and hospital-based outpatient clinics. Results of this study would be useful for further delineation of health care utilization of children in the context of a health care system unique to Japan. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553866 Fri, 30 Dec 2011 05:00:00 +0100 5553866 http://www.medworm.com/index.php?rid=5553865&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2F108%3Frss%3D1 Conclusions: This is the first study to demonstrate efficacy in a prevention program designed to deter conduct problems, substance use, substance use problems, and depressive symptoms among rural black adolescents. Because SAAF–T is a manualized, structured program, it can be easily disseminated to public health agencies, schools, churches, boys’ and girls’ clubs, and other community organizations. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553865 Fri, 30 Dec 2011 05:00:00 +0100 5553865 http://www.medworm.com/index.php?rid=5553864&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2Fe106%3Frss%3D1 Conclusions: This trial demonstrated that the Adolescent Asthma Action program can be readily adapted to suit different cultures and contexts. Adolescents in Jordan were successful in teaching their peers about asthma self-management and motivating them to avoid smoking. The findings revealed that peer education can be a useful strategy for health promotion programs in Jordanian schools when students are given the opportunity and training. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553864 Fri, 30 Dec 2011 05:00:00 +0100 5553864 http://www.medworm.com/index.php?rid=5553863&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2F99%3Frss%3D1 Conclusions We found that increasing SDM was associated with decreased utilization and expenditures for CSHCN. Prospective study is warranted to confirm if fostering SDM reduces the costs of caring for CSHCN for the health system and families. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553863 Fri, 30 Dec 2011 05:00:00 +0100 5553863 http://www.medworm.com/index.php?rid=5553862&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2Fe97%3Frss%3D1 Conclusion: Despite their high-risk start to life and a series of potential shortcomings, subjects born preterm may achieve normal exercise capacity, and their response to physical training seems comparable to peers born at term. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553862 Fri, 30 Dec 2011 05:00:00 +0100 5553862 http://www.medworm.com/index.php?rid=5553861&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2Fe89%3Frss%3D1 Conclusions: Preterm birth impairs the normal maturational increase in BRS, resulting in a substantial reduction in BRS at 5 to 6 months CA during QS. Lower BRS during QS compared with AS at 2 to 3 months CA may place preterm infants at an increased risk for cardiovascular instability at this age of peak incidence of SIDS. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553861 Fri, 30 Dec 2011 05:00:00 +0100 5553861 http://www.medworm.com/index.php?rid=5553860&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2F87%3Frss%3D1 Conclusions: For children without special health care needs, the medical home is associated with improved health care utilization patterns, better parental assessment of child health, and increased adherence with health-promoting behaviors. These findings support the recommendations of the American Academy of Pediatrics and the Affordable Care Act to extend the medical home to all children. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553860 Fri, 30 Dec 2011 05:00:00 +0100 5553860 http://www.medworm.com/index.php?rid=5553859&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2Fe82%3Frss%3D1 Conclusion: Obesity and Hispanic ethnicity are strongly correlated with symptomatic pediatric gallbladder disease. In comparison with our historical series, hemolytic disease is no longer the predominant risk factor for symptomatic gallstone disease in children. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553859 Fri, 30 Dec 2011 05:00:00 +0100 5553859 http://www.medworm.com/index.php?rid=5553858&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2F77%3Frss%3D1 Conclusions: Integration of routine hospital and community TcB screening within a comprehensive public health nurse newborn follow-up program is associated with significant improvements in resource utilization and patient safety. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553858 Fri, 30 Dec 2011 05:00:00 +0100 5553858 http://www.medworm.com/index.php?rid=5553857&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2Fe74%3Frss%3D1 CONCLUSIONS: The odds of having an HIV-infected infant were higher among HIV-infected women who were tested late, had no antiretroviral medications, abused substances, breastfed, or had lower CD4 cell counts. Increases in earlier HIV diagnosis, substance abuse treatment, avoidance of breastfeeding, and use of prenatal antiretroviral medications are critical in eliminating perinatal HIV infections in the United States. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553857 Fri, 30 Dec 2011 05:00:00 +0100 5553857 http://www.medworm.com/index.php?rid=5553856&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2F70%3Frss%3D1 Conclusions: Our study indicates that high BMI during the first 4 years does not increase the risk of asthma at school age among children who have developed a normal weight by age 7 years. However, high BMI at age 7 years is associated with an increased risk of asthma and sensitization to inhalant allergens. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553856 Fri, 30 Dec 2011 05:00:00 +0100 5553856 http://www.medworm.com/index.php?rid=5553855&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2Fe68%3Frss%3D1 Conclusions: Early childhood risk exposure leads to larger gains in BMI in adolescence. Given the importance of childhood adiposity to the development of obesity later in life, understanding the underlying mechanisms that link early experience to weight gain is an essential task. Deficiencies in self-regulation in response to chronic stress appears to be an important agent in the obesity epidemic. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553855 Fri, 30 Dec 2011 05:00:00 +0100 5553855 http://www.medworm.com/index.php?rid=5553854&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2F62%3Frss%3D1 Conclusions: Between 1988 and 2008, the use of PAM increased among children with current asthma. Non-Hispanic black and Mexican American children, adolescents aged 12 to 19 years, and uninsured children with current asthma had lower use of PAM. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553854 Fri, 30 Dec 2011 05:00:00 +0100 5553854 http://www.medworm.com/index.php?rid=5553853&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2Fe60%3Frss%3D1 Conclusions: HRV is an important and frequent pathogen associated with severe respiratory infections in VLBW infants. Bronchopulmonary dysplasia and the absence of breastfeeding are risk factors for hospitalization. The results of our study reveal that HRV is the predominant pathogen of respiratory infections in premature infants. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553853 Fri, 30 Dec 2011 05:00:00 +0100 5553853 http://www.medworm.com/index.php?rid=5553852&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2F55%3Frss%3D1 Conclusions: In a primary practice, use of palivizumab outside of the AAP guidelines was frequent and manifested as inadequate indications or inadequate number of doses. The former improved with education and standardization of care (suggesting provider problems), while the latter did not (suggesting system problems). Additional interventions are required. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553852 Fri, 30 Dec 2011 05:00:00 +0100 5553852 http://www.medworm.com/index.php?rid=5553851&cid=s_32770_33_f&fid=32770&url=http%3A%2F%2Fpediatrics.aappublications.org%2Fcgi%2Fcontent%2Fabstract%2F129%2F1%2Fe54%3Frss%3D1 Conclusions: This large cohort study did not find an association of influenza vaccination and hospitalization for sickle cell crises in children with sickle cell anemia. (Source: PEDIATRICS) PEDIATRICS journals http://www.medworm.com/rss/comments.php?id=5553851 Fri, 30 Dec 2011 05:00:00 +0100 5553851