MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'PLoS Medicine' source. Thu, 09 Feb 2012 09:15:16 +0100 http://www.medworm.com/index.php?rid=5672286&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2Fm2MG_ulEXkY%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001167 by Edward J. Mills, Chris Beyrer, Josephine Birungi, Mark R. Dybul (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5672286 Tue, 07 Feb 2012 05:00:00 +0100 5672286 http://www.medworm.com/index.php?rid=5672285&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FaFsgkynzI4c%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001170 Conclusions An algorithm-derived diagnosis of aMCI showed few sociodemographic associations but was consistently associated with higher disability and neuropsychiatric symptoms in addition to showing substantial variation in prevalence across LAMIC populations. Longitudinal data are needed to confirm findings—in particular, to investigate the predictive validity of aMCI in these settings and risk/protective factors for progression to dementia; however, the large number affected has important implications in these rapidly ageing settings. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5672285 Tue, 07 Feb 2012 05:00:00 +0100 5672285 http://www.medworm.com/index.php?rid=5672284&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2F-D9yyycjQcw%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001172 Conclusions In an endemic setting with well-implemented infection control measures, ward-based contact with symptomatic enzyme-immunoassay-positive patients cannot account for most new CDI cases. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5672284 Tue, 07 Feb 2012 05:00:00 +0100 5672284 http://www.medworm.com/index.php?rid=5672283&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FcG47VTFr2j8%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001171 by Stephan Harbarth, Matthew H. Samore (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5672283 Tue, 07 Feb 2012 05:00:00 +0100 5672283 http://www.medworm.com/index.php?rid=5654488&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2F8hOIPKhWcoA%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001166 Conclusions Results suggest that strengthening particular facets of mental health systems might improve availability of psychotropic medicines and that overall country development is associated with affordability. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5654488 Tue, 31 Jan 2012 05:00:00 +0100 5654488 http://www.medworm.com/index.php?rid=5654487&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2F7N4xXSLLpH4%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001165 by Teun Bousema, Jamie T. Griffin, Robert W. Sauerwein, David L. Smith, Thomas S. Churcher, Willem Takken, Azra Ghani, Chris Drakeley, Roly Gosling (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5654487 Tue, 31 Jan 2012 05:00:00 +0100 5654487 http://www.medworm.com/index.php?rid=5654486&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FecEh2MKwKEk%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001164 This study evaluated the effectiveness of two commercial e-prescribing systems in reducing prescribing error rates and their propensities for introducing new types of error. Methods and Results We conducted a before and after study involving medication chart audit of 3,291 admissions (1,923 at baseline and 1,368 post e-prescribing system) at two Australian teaching hospitals. In Hospital A, the Cerner Millennium e-prescribing system was implemented on one ward, and three wards, which did not receive the e-prescribing system, acted as controls. In Hospital B, the iSoft MedChart system was implemented on two wards and we compared before and after error rates. Procedural (e.g., unclear and incomplete prescribing orders) and clinical (e.g., wrong dose, wrong drug) errors were identified. Presc... PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5654486 Tue, 31 Jan 2012 05:00:00 +0100 5654486 http://www.medworm.com/index.php?rid=5654485&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FCfy5TmJ0dc4%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001168 by The PLoS Medicine Editors (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5654485 Tue, 31 Jan 2012 05:00:00 +0100 5654485 http://www.medworm.com/index.php?rid=5633651&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FeeHvbHnyNGA%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001162 Conclusions Despite a number of limitations (e.g., most studies used a cross-sectional design and were of low quality, with potential biases and considerable heterogeneity), our results reveal that sanitation is associated with a reduced risk of transmission of helminthiases to humans. Access to improved sanitation should be prioritized alongside preventive chemotherapy and health education to achieve a durable reduction of the burden of helminthiases. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5633651 Tue, 24 Jan 2012 05:00:00 +0100 5633651 http://www.medworm.com/index.php?rid=5633650&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FV6L4Qy0E9U8%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001160 Conclusions Tobacco smoking and high blood pressure are the two major risk factors for adult mortality from non-communicable diseases and injuries in Japan. There is a large potential population health gain if multiple risk factors are jointly controlled. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5633650 Tue, 24 Jan 2012 05:00:00 +0100 5633650 http://www.medworm.com/index.php?rid=5633649&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FKHT_wTE1FXM%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001163 by Xavier Bosch, Bijan Esfandiari, Leemon McHenry (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5633649 Tue, 24 Jan 2012 05:00:00 +0100 5633649 http://www.medworm.com/index.php?rid=5602462&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2Fz50yNwZgsG8%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001157 Conclusions In higher transmission settings, EPI strategies will be most efficient, but vaccination additional to the EPI in targeted low transmission settings, even at modest coverage, might be more efficient than national-level vaccination of infants. The feasibility and economics of mass vaccination, and the circumstances under which vaccination will avert epidemics, remain unclear. The approach of using an ensemble of models provides more secure conclusions than a single-model approach, and suggests greater confidence in predictions of health effects for lower transmission settings than for higher ones. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5602462 Tue, 17 Jan 2012 05:00:00 +0100 5602462 http://www.medworm.com/index.php?rid=5602461&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FoHpLHNiThtw%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001161 by Grant A. Mackenzie, Ian D. Plumb, Sana Sambou, Debasish Saha, Uchendu Uchendu, Bolanle Akinsola, Usman N. Ikumapayi, Ignatius Baldeh, Effua Usuf, Kebba Touray, Momodou Jasseh, Stephen R. C. Howie, Andre Wattiaux, Ellen Lee, Maria Deloria Knoll, Orin S. Levine, Brian M. Greenwood, Richard A. Adegbola, Philip C. Hill (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5602461 Tue, 17 Jan 2012 05:00:00 +0100 5602461 http://www.medworm.com/index.php?rid=5602460&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FpxgArCDz-PY%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001159 by Judith K. Bass, Thomas H. Bornemann, Matthew Burkey, Sonia Chehil, Lenis Chen, John R. M. Copeland, William W. Eaton, Vijay Ganju, Erin Hayward, Rebecca S. Hock, Rubeena Kidwai, Kavitha Kolappa, Patrick T. Lee, Harry Minas, Flora Or, Giuseppe J. Raviola, Benedetto Saraceno, Vikram Patel (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5602460 Tue, 17 Jan 2012 05:00:00 +0100 5602460 http://www.medworm.com/index.php?rid=5602459&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2Fz_7ieJPAgPQ%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001158 by Jay G. Berry, Annapurna Poduri, Joshua L. Bonkowsky, Jing Zhou, Dionne A. Graham, Chelsea Welch, Heather Putney, Rajendu Srivastava Background Care advances in the United States (US) have led to improved survival of children with neurological impairment (NI). Children with NI may account for an increasing proportion of hospital resources. However, this assumption has not been tested at a national level. Methods and Findings We conducted a study of 25,747,016 US hospitalizations of children recorded in the Kids' Inpatient Database (years 1997, 2000, 2003, and 2006). Children with NI were identified with International Classification of Diseases, 9th Revision, Clinical Modification diagnoses resulting in functional and/or intellectual impairment. We assessed trends in inpatient resource ut... PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5602459 Tue, 17 Jan 2012 05:00:00 +0100 5602459 http://www.medworm.com/index.php?rid=5590692&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2F1hRGzZdALgo%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001154 Conclusions Given skepticism about the Doha Declaration's likely impact, we note the relatively high occurrence of CLs, yet CL activity has diminished markedly since 2006. While UMICs have high CL activity and strong incentives to use CLs compared to other countries, we note considerable countervailing pressures against CL use even in UMICs. We conclude that there is a low probability of continued CL activity. We highlight the need for further systematic evaluation of global health governance actions. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5590692 Tue, 10 Jan 2012 05:00:00 +0100 5590692 http://www.medworm.com/index.php?rid=5590691&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2F5CB8IiwQ-bs%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001156 Conclusions Implementation of the WHO PMTCT guidelines must be accompanied by efforts to improve access to PMTCT services, retain women in care, and support medication adherence throughout pregnancy and breastfeeding, to approach the “virtual elimination” of pediatric HIV in Zimbabwe. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5590691 Tue, 10 Jan 2012 05:00:00 +0100 5590691 http://www.medworm.com/index.php?rid=5590690&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FYgLAgFB6jvQ%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001153 by Jason W. Nickerson, Amir Attaran (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5590690 Tue, 10 Jan 2012 05:00:00 +0100 5590690 http://www.medworm.com/index.php?rid=5590689&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2F4jzjvBSoEzo%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001155 Conclusions Patients who experienced a first venous thrombosis had an increased risk of death which lasted up to 8 years after the event, even when no comorbidities were present at time of thrombosis. Future long-term clinical follow-up could be beneficial in these patients. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5590689 Tue, 10 Jan 2012 05:00:00 +0100 5590689 http://www.medworm.com/index.php?rid=5548629&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FqySqnZeYbfQ%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001152 by The PLoS Medicine Editors (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5548629 Tue, 27 Dec 2011 05:00:00 +0100 5548629 http://www.medworm.com/index.php?rid=5548628&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FuN_MsE6hAjo%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001151 by Anna Nordström, Peter Nordström Background There are few identified risk factors for traumatic brain injuries such as subdural hematoma (SDH). The aim of the present study was to investigate whether low cognitive performance in young adulthood is associated with SDH later in life. A second aim was to investigate whether this risk factor was associated with education and physical fitness. Methods and Findings Word recollection, logical, visuospatial, and technical performances were tested at a mean age of 18.5 years in a prospective nation-wide cohort of 440,742 men. An estimate of global intelligence was calculated from these four tests. Associations between cognitive performance, education, physical fitness, and SDH during follow-up were explored using Cox regression analyses. During... PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5548628 Tue, 27 Dec 2011 05:00:00 +0100 5548628 http://www.medworm.com/index.php?rid=5548627&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2Fr8pFbopvbwg%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001149 by Rafael Dal-Ré, David Moher, Christian Gluud, Shaun Treweek, Jacques Demotes-Mainard, Xavier Carné (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5548627 Tue, 27 Dec 2011 05:00:00 +0100 5548627 http://www.medworm.com/index.php?rid=5548626&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2F3WnlM_oSI1Y%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001148 by Jan Volavka (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5548626 Tue, 27 Dec 2011 05:00:00 +0100 5548626 http://www.medworm.com/index.php?rid=5548625&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FXsiWs5wQR-c%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001150 Conclusions In this longitudinal population-based study, we found that, after adjustment for familial confounding, epilepsy was not associated with increased risk of violent crime, questioning expert opinion that has suggested a causal relationship. In contrast, although there was some attenuation in risk estimates after adjustment for familial factors and substance abuse in individuals with traumatic brain injury, we found a significantly increased risk of violent crime. The implications of these findings will vary for clinical services, the criminal justice system, and patient charities. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5548625 Tue, 27 Dec 2011 05:00:00 +0100 5548625 http://www.medworm.com/index.php?rid=5531068&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FmcbvjccAYTM%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001147 Conclusions Increasing vaccine uptake among preadolescent girls is more effective in reducing HPV infection than including boys in existing vaccination programs. As a rule, directing prophylactic immunization at the sex with the highest prevaccine prevalence results in the largest reduction of the population prevalence. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5531068 Tue, 20 Dec 2011 05:00:00 +0100 5531068 http://www.medworm.com/index.php?rid=5531067&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FYT-UTYd3OYE%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001144 by Ivo Mueller, Laurence S.sker, Marcel Tanner (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5531067 Tue, 20 Dec 2011 05:00:00 +0100 5531067 http://www.medworm.com/index.php?rid=5531066&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FnLgHsH-JMaQ%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001142 Conclusions Estimates of malaria incidence derived from routine surveillance data were typically lower than those derived from surveys of parasite prevalence. Carefully interpreted surveillance data can be used to monitor malaria trends in response to control efforts, and to highlight areas where malaria programs and health information systems need to be strengthened. As malaria incidence declines around the world, evaluation of control efforts will increasingly rely on robust systems of routine surveillance. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5531066 Tue, 20 Dec 2011 05:00:00 +0100 5531066 http://www.medworm.com/index.php?rid=5531065&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FLo6ukzJMs1k%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001146 by Noriko Fujita, Anthony B. Zwi, Mari Nagai, Hidechika Akashi (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5531065 Tue, 20 Dec 2011 05:00:00 +0100 5531065 http://www.medworm.com/index.php?rid=5531064&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FUHmednq4Uqo%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001145 Conclusion The case study of Project MIX shows tobacco industry scientific research on the use of cigarette additives cannot be taken at face value. The results demonstrate that toxins in cigarette smoke increase substantially when additives are put in cigarettes, including the level of TPM. In particular, regulatory authorities, including the FDA and similar agencies elsewhere, could use the Project MIX data to eliminate the use of these 333 additives (including menthol) from cigarettes. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5531064 Tue, 20 Dec 2011 05:00:00 +0100 5531064 http://www.medworm.com/index.php?rid=5499807&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FEk_N1hn6vFA%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001143 by Judith G. M. Rosmalen, Albertine J. Oldehinkel (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5499807 Tue, 13 Dec 2011 05:00:00 +0100 5499807 http://www.medworm.com/index.php?rid=5499806&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2Fpd38Iq8Y9fY%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001137 Conclusions There was no evidence that use of absorbable polyglactin-910 sutures was associated with a lower prevalence of trichiasis recurrence at 1 year postsurgery than silk sutures. However, from a programmatic perspective, polyglactin-910 offers the major advantage that patients do not have to be seen soon after surgery for suture removal. The postoperative review after surgery using absorbable polyglactin-910 sutures can be delayed for 3–6 months, which might allow us to better determine whether a patient needs additional surgery. Trial registration ClinicalTrials.gov NCT00522860 Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5499806 Tue, 13 Dec 2011 05:00:00 +0100 5499806 http://www.medworm.com/index.php?rid=5499805&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FaS2N18Tof3E%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001136 by Saul N. Rajak, Esmael Habtamu, Helen A. Weiss, Amir Bedri Kello, Teshome Gebre, Asrat Genet, Robin L. Bailey, David C. W. Mabey, Peng T. Khaw, Clare E. Gilbert, Paul M. Emerson, Matthew J. Burton Background Trachomatous trichiasis can cause corneal damage and visual impairment. WHO recommends surgery for all cases. However, in many regions surgical provision is inadequate and patients frequently decline. Self-epilation is common and was associated with comparable outcomes to surgery in nonrandomised studies for minor trichiasis ( (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5499805 Tue, 13 Dec 2011 05:00:00 +0100 5499805 http://www.medworm.com/index.php?rid=5481583&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FDek9isn24o8%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001141 by An Pan, Eva S. Schernhammer, Qi Sun, Frank B. Hu Background Rotating night shift work disrupts circadian rhythms and has been associated with obesity, metabolic syndrome, and glucose dysregulation. However, its association with type 2 diabetes remains unclear. Therefore, we aimed to evaluate this association in two cohorts of US women. Methods and Findings We followed 69,269 women aged 42–67 in Nurses' Health Study I (NHS I, 1988–2008), and 107,915 women aged 25–42 in NHS II (1989–2007) without diabetes, cardiovascular disease, and cancer at baseline. Participants were asked how long they had worked rotating night shifts (defined as at least three nights/month in addition to days and evenings in that month) at baseline. This information was updated every 2–4 years in NHS II. S... PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5481583 Tue, 06 Dec 2011 05:00:00 +0100 5481583 http://www.medworm.com/index.php?rid=5481582&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FP1BfDiGegKY%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001138 by Mika Kivimäki, G. David Batty, Christer Hublin (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5481582 Tue, 06 Dec 2011 05:00:00 +0100 5481582 http://www.medworm.com/index.php?rid=5481581&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FtbM0t6Bus0M%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001140 Conclusions The use of disability weights derived from patient experiences combined with additional morbidity data on ED-treated patients and inpatients suggests that the absolute burden of injury is higher than previously estimated. These findings have substantial implications for improving measurement of the national and global burden of injury. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5481581 Tue, 06 Dec 2011 05:00:00 +0100 5481581 http://www.medworm.com/index.php?rid=5481580&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FTzRa6Gh7kG8%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001139 by Paul N. Newton, Abdinasir A. Amin, Chris Bird, Phillip Passmore, Graham Dukes, Göran Tomson, Bright Simons, Roger Bate, Philippe J. Guerin, Nicholas J. White (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5481580 Tue, 06 Dec 2011 05:00:00 +0100 5481580 http://www.medworm.com/index.php?rid=5463497&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FriHHtlRxM80%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001129 by Kelly Curran, Emmanuel Njeuhmeli, Andrew Mirelman, Kim Dickson, Tigistu Adamu, Peter Cherutich, Hally Mahler, Bennett Fimbo, Thembisile Khumalo Mavuso, Jennifer Albertini, Laura Fitzgerald, Naomi Bock, Jason Reed, Delivette Castor, David Stanton Voluntary medical male circumcision (VMMC) reduces female-to-male HIV transmission by approximately 60%; modeling suggests that scaling up VMMC to 80% of men 15- to 49-years-old within five years would avert over 3.3 million new HIV infections in 14 high priority countries/regions in southern and eastern Africa by 2025 and would require 20.33 million circumcisions. However, the shortage of health professionals in these countries must be addressed to reach these proposed coverage levels. To identify human resource approaches that are being u... PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5463497 Tue, 29 Nov 2011 05:00:00 +0100 5463497 http://www.medworm.com/index.php?rid=5463496&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FQ9CbwQLHueg%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001131 by Hally R. Mahler, Baldwin Kileo, Kelly Curran, Marya Plotkin, Tigistu Adamu, Augustino Hellar, Sifuni Koshuma, Simeon Nyabenda, Michael Machaku, Mainza Lukobo-Durrell, Delivette Castor, Emmanuel Njeuhmeli, Bennett Fimbo The government of Tanzania has adopted voluntary medical male circumcision (VMMC) as an important component of its national HIV prevention strategy and is scaling up VMMC in eight regions nationwide, with the goal of reaching 2.8 million uncircumcised men by 2015. In a 2010 campaign lasting six weeks, five health facilities in Tanzania's Iringa Region performed 10,352 VMMCs, which exceeded the campaign's target by 72%, with an adverse event (AE) rate of 1%. HIV testing was almost universal during the campaign. Through the adoption of approaches designed to improve cl... PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5463496 Tue, 29 Nov 2011 05:00:00 +0100 5463496 http://www.medworm.com/index.php?rid=5463495&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FT8_Sn7X--jE%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001134 by Samantha R. Lattof, Mary Nell Wegner, Ana Langer, and the PLoS Medicine Editors (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5463495 Tue, 29 Nov 2011 05:00:00 +0100 5463495 http://www.medworm.com/index.php?rid=5463494&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2Fbo-8rsXAlYc%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001130 by Zebedee Mwandi, Anne Murphy, Jason Reed, Kipruto Chesang, Emmanuel Njeuhmeli, Kawango Agot, Emma Llewellyn, Charles Kirui, Kennedy Serrem, Isaac Abuya, Mores Loolpapit, Regina Mbayaki, Ndungu Kiriro, Peter Cherutich, Nicholas Muraguri, John Motoku, Jack Kioko, Nancy Knight, Naomi Bock Since the World Health Organization and the Joint United Nations Programme on HIV/AIDS recommended implementation of medical male circumcision (MC) as part of HIV prevention in areas with low MC and high HIV prevalence rates in 2007, the government of Kenya has developed a strategy to circumcise 80% of uncircumcised men within five years. To facilitate the quick translation of research to practice, a national MC task force was formed in 2007, a medical MC policy was implemented in early 2008, and Nyan... PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5463494 Tue, 29 Nov 2011 05:00:00 +0100 5463494 http://www.medworm.com/index.php?rid=5463493&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FZe2QjsqEBbg%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001128 Conclusions Experience with the VMMC program in Swaziland indicates that supply chain and waste management add approximately US$60 per circumcision, nearly doubling the total per procedure cost estimated previously; these additional costs are used to inform the estimate of per procedure costs modeled by Njeuhmeli et al. in “Voluntary Medical Male Circumcision: Modeling the Impact and Cost of Expanding Male Circumcision for HIV Prevention in Eastern and Southern Africa.” Program planners and policy makers should consider the significant contribution of supply chain and waste management to VMMC program costs as they determine future resource needs for VMMC programs. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5463493 Tue, 29 Nov 2011 05:00:00 +0100 5463493 http://www.medworm.com/index.php?rid=5463492&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FXDKsj5Emt-I%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001132 Conclusions This study suggests that rapid scale-up of VMMC in eastern and southern Africa is warranted based on the likely impact on the region's HIV epidemics and net savings. Scaling up of safe VMMC in eastern and southern Africa will lead to a substantial reduction in HIV infections in the countries and lower health system costs through averted HIV care costs. Please see later in the article for the Editors' Summary. (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5463492 Tue, 29 Nov 2011 05:00:00 +0100 5463492 http://www.medworm.com/index.php?rid=5463491&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FhXWlDfdrdoQ%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001135 by Christian Lienhardt, Marcos Espinal, Madhukar Pai, Dermot Maher, Mario C. Raviglione (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5463491 Tue, 29 Nov 2011 05:00:00 +0100 5463491 http://www.medworm.com/index.php?rid=5463490&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FY4Wz5ov3SmM%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001133 Conclusions Early adoption of VMMC policies did not necessarily result in rapid program scale-up. A key lesson is the importance of not only being ready to adopt a new intervention but also ensuring that factors critical to supporting and accelerating scale-up are incorporated into the program. The most successful program had country ownership and sustained leadership to translate research into a national policy and program. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5463490 Tue, 29 Nov 2011 05:00:00 +0100 5463490 http://www.medworm.com/index.php?rid=5463489&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2Fnoh45zH60WQ%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001127 by Catherine Hankins, Steven Forsythe, Emmanuel Njeuhmeli Scaling up voluntary medical male circumcision (VMMC) for HIV prevention is cost saving and creates fiscal space in the future that otherwise would have been encumbered by antiretroviral treatment costs. An investment of US$1,500,000,000 between 2011 and 2015 to achieve 80% coverage in 13 priority countries in southern and eastern Africa will result in net savings of US$16,500,000,000. Strong political leadership, country ownership, and stakeholder engagement, along with effective demand creation, community mobilisation, and human resource deployment, are essential. This collection of articles on determining the cost and impact of VMMC for HIV prevention signposts the way forward to scaling up VMMC service delivery safely and e... PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5463489 Tue, 29 Nov 2011 05:00:00 +0100 5463489 http://www.medworm.com/index.php?rid=5435944&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2F-FiTvE1iaoI%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001126 by M. Taghi Yasamy, Pallab K. Maulik, Mark Tomlinson, Crick Lund, Mark Van Ommeren, Shekhar Saxena (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5435944 Tue, 22 Nov 2011 05:00:00 +0100 5435944 http://www.medworm.com/index.php?rid=5435943&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FopPIsr8805M%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001125 by Jacobien Veenemans, Paul Milligan, Andrew M. Prentice, Laura R. A. Schouten, Nienke Inja, Aafke C. van der Heijden, Linsey C. C. de Boer, Esther J. S. Jansen, Anna E. Koopmans, Wendy T. M. Enthoven, Rob J. Kraaijenhagen, Ayse Y. Demir, Donald R. A. Uges, Erasto V. Mbugi, Huub F. J. Savelkoul, Hans Verhoef Background It is uncertain to what extent oral supplementation with zinc can reduce episodes of malaria in endemic areas. Protection may depend on other nutrients. We measured the effect of supplementation with zinc and other nutrients on malaria rates. Methods and Findings In a 2×2 factorial trial, 612 rural Tanzanian children aged 6–60 months in an area with intense malaria transmission and with height-for-age z-score≤−1.5 SD were randomized to receive daily oral supplementati... PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5435943 Tue, 22 Nov 2011 05:00:00 +0100 5435943 http://www.medworm.com/index.php?rid=5435942&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2F3c84Db6xMYM%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001124 Conclusions HIV-positive women described interdependent and mutually constitutive relationships between marginalized social identities and inequities such as HIV-related stigma, sexism, racism, and homo/transphobia. These overlapping, multilevel forms of stigma and discrimination are representative of an intersectional model of stigma and discrimination. The present findings also suggest that micro, meso, and macro level factors simultaneously present barriers to health and well being—as well as opportunities for coping—in HIV-positive women's lives. Understanding the deleterious effects of stigma and discrimination on HIV risk, mental health, and access to care among HIV-positive women can inform health care provision, stigma reduction interventions, and public health policy. P... PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5435942 Tue, 22 Nov 2011 05:00:00 +0100 5435942 http://www.medworm.com/index.php?rid=5415304&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FClQGfuJqTw4%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001122 by Tarun Dua, Corrado Barbui, Nicolas Clark, Alexandra Fleischmann, Vladimir Poznyak, Mark van Ommeren, M. Taghi Yasamy, Jose Luis Ayuso-Mateos, Gretchen L. Birbeck, Colin Drummond, Melvyn Freeman, Panteleimon Giannakopoulos, Itzhak Levav, Isidore S. Obot, Olayinka Omigbodun, Vikram Patel, Michael Phillips, Martin Prince, Afarin Rahimi-Movaghar, Atif Rahman, Josemir W. Sander, John B. Saunders, Chiara Servili, Thara Rangaswamy, Jürgen Unützer, Peter Ventevogel, Lakshmi Vijayakumar, Graham Thornicroft, Shekhar Saxena (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5415304 Tue, 15 Nov 2011 05:00:00 +0100 5415304 http://www.medworm.com/index.php?rid=5415303&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FJELmcLUhAOA%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001123 Conclusions Strategic use of PrEP and ART could substantially and cost-effectively reduce HIV-1 transmission in HIV-1 serodiscordant couples. New and forthcoming data on the efficacy of PrEP, the cost of delivery of ART and PrEP, and couples behaviours and preferences will be critical for optimizing the use of antiretrovirals for HIV-1 prevention. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5415303 Tue, 15 Nov 2011 05:00:00 +0100 5415303 http://www.medworm.com/index.php?rid=5394387&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FIFZ43RauK0k%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001120 Conclusions Our results suggest that Xpert is a cost-effective method of TB diagnosis, compared to a base case of smear microscopy and clinical diagnosis of smear-negative TB in low- and middle-income settings where, with its ability to substantially increase case finding, it has important potential for improving TB diagnosis and control. The extent of cost-effectiveness gain to TB programmes from deploying Xpert is primarily dependent on current TB diagnostic practices. Further work is required during scale-up to validate these findings. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5394387 Tue, 08 Nov 2011 05:00:00 +0100 5394387 http://www.medworm.com/index.php?rid=5394386&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FNP-Z85jw1ts%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001121 by Melissa Gladstone, Sarah White, George Kafulafula, James P. Neilson, Nynke van den Broek Background Preterm birth is considered to be associated with an estimated 27% of neonatal deaths, the majority in resource-poor countries where rates of prematurity are high. There is no information on medium term outcomes after accurately determined preterm birth in such settings. Methods and Findings This community-based stratified cohort study conducted between May–December 2006 in Southern Malawi followed up 840 post-neonatal infants born to mothers who had received antenatal antibiotic prophylaxis/placebo in an attempt to reduce rates of preterm birth (APPLe trial ISRCTN84023116). Gestational age at delivery was based on ultrasound measurement of fetal bi-parietal diameter in early-mid pregna... PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5394386 Tue, 08 Nov 2011 05:00:00 +0100 5394386 http://www.medworm.com/index.php?rid=5394385&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FIGJUQjxpQuc%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001119 Conclusions This large head-to-head comparison of most currently available ACTs in sub-Saharan Africa showed that AL, ASAQ, and DHAPQ had excellent efficacy, up to day 63 post-treatment. The risk of recurrent infections was significantly lower for DHAPQ, followed by ASAQ and then AL, supporting the recent recommendation of considering DHAPQ as a valid option for the treatment of uncomplicated P. falciparum malaria. Trial Registration ClinicalTrials.gov NCT00393679; Pan African Clinical Trials Registry PACTR2009010000911750 Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5394385 Tue, 08 Nov 2011 05:00:00 +0100 5394385 http://www.medworm.com/index.php?rid=5394384&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2F0tNrdAWcAus%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001118 by Vanessa B. Kerry, Thumbi Ndung'u, Rochelle P. Walensky, Patrick T. Lee, V. Frederick I. B. Kayanja, David R. Bangsberg (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5394384 Tue, 08 Nov 2011 05:00:00 +0100 5394384 http://www.medworm.com/index.php?rid=5371862&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FWdRAQ94gycE%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001115 by Piroska Östlin, Ted Schrecker, Ritu Sadana, Josiane Bonnefoy, Lucy Gilson, Clyde Hertzman, Michael P. Kelly, Tord Kjellstrom, Ronald Labonté, Olle Lundberg, Carles Muntaner, Jennie Popay, Gita Sen, Ziba Vaghri (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5371862 Tue, 01 Nov 2011 04:00:00 +0100 5371862 http://www.medworm.com/index.php?rid=5371861&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FzkPuABaHZMU%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001116 Conclusions The association of the FTO risk allele with the odds of obesity is attenuated by 27% in physically active adults, highlighting the importance of PA in particular in those genetically predisposed to obesity. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5371861 Tue, 01 Nov 2011 04:00:00 +0100 5371861 http://www.medworm.com/index.php?rid=5371860&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FPRupRYqjHSM%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001114 by J. Lennert Veerman (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5371860 Tue, 01 Nov 2011 04:00:00 +0100 5371860 http://www.medworm.com/index.php?rid=5353539&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FUoNbIu511-U%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001117 by Valentina Gallo, Matthias Egger, Valerie McCormack, Peter B. Farmer, John P. A. Ioannidis, Micheline Kirsch-Volders, Giuseppe Matullo, David H. Phillips, Bernadette Schoket, Ulf Stromberg, Roel Vermeulen, Christopher Wild, Miquel Porta, Paolo Vineis (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5353539 Tue, 25 Oct 2011 04:00:00 +0100 5353539 http://www.medworm.com/index.php?rid=5353538&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2Fz5MTpI4Tgb4%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001113 by The PLoS Medicine Editors (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5353538 Tue, 25 Oct 2011 04:00:00 +0100 5353538 http://www.medworm.com/index.php?rid=5353537&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2Fdt3-YpcCL_0%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001112 Conclusions Our results provide evidence for a potential causal role of the BNP system in the aetiology of T2D. Further studies are needed to investigate the mechanisms underlying this association and possibilities for preventive interventions. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5353537 Tue, 25 Oct 2011 04:00:00 +0100 5353537 http://www.medworm.com/index.php?rid=5353536&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FOJ1pazsJCCs%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001111 Conclusions Based on this evaluation, we recommend the adoption of ≥180 d since the last clinic visit as a standard LTFU definition. Such standardization is an important step to understanding the reasons that underlie patient attrition and establishing more reliable and comparable program evaluation worldwide. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5353536 Tue, 25 Oct 2011 04:00:00 +0100 5353536 http://www.medworm.com/index.php?rid=5353535&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2F579J1Ob2_Tc%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001110 Conclusions Combining administrative data with survey data substantially improves estimates of vaccination coverage. Estimates of the inefficiency of past vaccination activities and the proportion not covered by any activity allow us to more accurately predict the results of future activities and provide insight into the ways in which vaccination programs are failing to meet their goals. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5353535 Tue, 25 Oct 2011 04:00:00 +0100 5353535 http://www.medworm.com/index.php?rid=5328891&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FzP74T3R0PBU%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001109 by Kathleen M. O'Reilly, Claire Chauvin, R. Bruce Aylward, Chris Maher, Sam Okiror, Chris Wolff, Deo Nshmirimana, Christl A. Donnelly, Nicholas C. Grassly Background Outbreaks of poliomyelitis in African countries that were previously free of wild-type poliovirus cost the Global Polio Eradication Initiative US$850 million during 2003–2009, and have limited the ability of the program to focus on endemic countries. A quantitative understanding of the factors that predict the distribution and timing of outbreaks will enable their prevention and facilitate the completion of global eradication. Methods and Findings Children with poliomyelitis in Africa from 1 January 2003 to 31 December 2010 were identified through routine surveillance of cases of acute flaccid paralysis, and separate outbrea... PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5328891 Tue, 18 Oct 2011 04:00:00 +0100 5328891 http://www.medworm.com/index.php?rid=5328890&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2Fvlr6P6kBfzU%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001108 by Francesca Celletti, Teri A. Reynolds, Anna Wright, Aaron Stoertz, Manuel Dayrit (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5328890 Tue, 18 Oct 2011 04:00:00 +0100 5328890 http://www.medworm.com/index.php?rid=5328889&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2Fc84P2oh2RXQ%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001107 by Anna Roca, Philip C. Hill, John Townend, Uzo Egere, Martin Antonio, Abdoulie Bojang, Abiodun Akisanya, Teresa Litchfield, David E. Nsekpong, Claire Oluwalana, Stephen R. C. Howie, Brian Greenwood, Richard A. Adegbola Background Introduction of pneumococcal conjugate vaccines (PCVs) of limited valency is justified in Africa by the high burden of pneumococcal disease. Long-term beneficial effects of PCVs may be countered by serotype replacement. We aimed to determine the impact of PCV-7 vaccination on pneumococcal carriage in rural Gambia. Methods and Findings A cluster-randomized (by village) trial of the impact of PCV-7 on pneumococcal nasopharyngeal carriage was conducted in 21 Gambian villages between December 2003 to June 2008 (5,441 inhabitants in 2006). Analysis was complemented wi... PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5328889 Tue, 18 Oct 2011 04:00:00 +0100 5328889 http://www.medworm.com/index.php?rid=5309359&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2F-83vo3py8cs%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001105 by Philip C. Hill, Merrin E. Rutherford, Rick Audas, Reinout van Crevel, Stephen M. Graham (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5309359 Tue, 11 Oct 2011 04:00:00 +0100 5309359 http://www.medworm.com/index.php?rid=5309358&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FtDiB84Li4HU%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001106 Conclusions The risk of MI and CVD conferred by Chromosome 9p21 SNPs appears to be modified by a prudent diet high in raw vegetables and fruits. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5309358 Tue, 11 Oct 2011 04:00:00 +0100 5309358 http://www.medworm.com/index.php?rid=5309357&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FU9qZEvKFGeE%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001104 Conclusions Excess mortality associated with BSIs caused by MRSA and G3CREC is significant, and the prolongation of hospital stay imposes a considerable burden on health care systems. A foreseeable shift in the burden of antibiotic resistance from Gram-positive to Gram-negative infections will exacerbate this situation and is reason for concern. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5309357 Tue, 11 Oct 2011 04:00:00 +0100 5309357 http://www.medworm.com/index.php?rid=5291313&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FwSaOPEJ3MM8%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001103 Conclusions Serial cross-sectional serologic data together with clinical surveillance data can allow reliable real-time estimates of IAR and severity in an emerging pandemic. Sero-surveillance for pandemics should be considered. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5291313 Tue, 04 Oct 2011 04:00:00 +0100 5291313 http://www.medworm.com/index.php?rid=5291312&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FZLNC_f2xOHY%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001102 Conclusions Oral supervised self-testing was highly acceptable and accurate, although minor errors and need for supervisory support were common. This novel option has potential for high uptake at local community level if it can be supervised and safely linked to counseling and care. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5291312 Tue, 04 Oct 2011 04:00:00 +0100 5291312 http://www.medworm.com/index.php?rid=5291311&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FhkU_OAbAOrI%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001101 by Rochelle P. Walensky, Ingrid V. Bassett (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5291311 Tue, 04 Oct 2011 04:00:00 +0100 5291311 http://www.medworm.com/index.php?rid=5291310&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FBKyPE6pGjr8%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001100 by Peter A. Chow-White, Troy Duster (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5291310 Tue, 04 Oct 2011 04:00:00 +0100 5291310 http://www.medworm.com/index.php?rid=5266690&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FGYrkIcBZkqg%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001099 by Igor Rudan, Shams El Arifeen, Zulfiqar A. Bhutta, Robert E. Black, Abdullah Brooks, Kit Yee Chan, Mickey Chopra, Trevor Duke, David Marsh, Antonio Pio, Eric A.F. Simoes, Giorgio Tamburlini, Evropi Theodoratou, Martin W. Weber, Cynthia G. Whitney, Harry Campbell, Shamim A. Qazi, and the WHO/CHNRI Expert Group on Childhood Pneumonia (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5266690 Tue, 27 Sep 2011 04:00:00 +0100 5266690 http://www.medworm.com/index.php?rid=5266689&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FUHwCJiWw7yU%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001097 by The PLoS Medicine Editors (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5266689 Tue, 27 Sep 2011 04:00:00 +0100 5266689 http://www.medworm.com/index.php?rid=5266688&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FptO7ahOdaeU%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001098 Conclusions This review suggests that among widely used NSAIDs, naproxen and low-dose ibuprofen are least likely to increase cardiovascular risk. Diclofenac in doses available without prescription elevates risk. The data for etoricoxib were sparse, but in pair-wise comparisons this drug had a significantly higher RR than naproxen or ibuprofen. Indomethacin is an older, rather toxic drug, and the evidence on cardiovascular risk casts doubt on its continued clinical use. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5266688 Tue, 27 Sep 2011 04:00:00 +0100 5266688 http://www.medworm.com/index.php?rid=5244551&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2F9mTLJQUj2bU%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001096 by Wietse A. Tol, Vikram Patel, Mark Tomlinson, Florence Baingana, Ananda Galappatti, Catherine Panter-Brick, Derrick Silove, Egbert Sondorp, Michael Wessells, Mark van Ommeren (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5244551 Tue, 20 Sep 2011 04:00:00 +0100 5244551 http://www.medworm.com/index.php?rid=5244550&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2F8D4GQoquprc%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001095 Conclusions Initiating ART in HIV-infected adults with a CD4 cell count between 200 and 350 cells/mm3 in Haiti, consistent with World Health Organization advice, was cost-effective (US$/YLS (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5244550 Tue, 20 Sep 2011 04:00:00 +0100 5244550 http://www.medworm.com/index.php?rid=5244549&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2Fhit7EO8CZ70%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001094 by Kimmo Herttua, Pekka Martikainen, Jussi Vahtera, Mika Kivimäki Background Social isolation and living alone are increasingly common in industrialised countries. However, few studies have investigated the potential public health implications of this trend. We estimated the relative risk of death from alcohol-related causes among individuals living alone and determined whether this risk changed after a large reduction in alcohol prices. Methods and Findings We conducted a population-based natural experimental study of a change in the price of alcohol that occurred because of new laws enacted in Finland in January and March of 2004, utilising national registers. The data are based on an 11% sample of the Finnish population aged 15–79 y supplemented with an oversample of deaths. The over... PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5244549 Tue, 20 Sep 2011 04:00:00 +0100 5244549 http://www.medworm.com/index.php?rid=5216546&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FcqmDFG3Aijs%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001093 Conclusions The genomic characterization provided here substantially expands the scope by which the molecular response to trauma may be characterized and understood. These results may be instrumental in furthering our understanding of the disease process and identifying potential targets for therapeutic intervention. Additionally, the quantitative approach we have introduced is potentially applicable to future genomics studies of rapidly progressing clinical conditions. Trial Registration ClinicalTrials.gov NCT00257231 Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5216546 Tue, 13 Sep 2011 04:00:00 +0100 5216546 http://www.medworm.com/index.php?rid=5216545&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FdQYi3r8rmKU%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001092 Conclusions Genotyping for IL28B, HLA-C, and KIR genes improves prediction of HCV treatment response. These findings support a role for natural killer (NK) cell activation in PegIFN/R treatment-induced clearance, partially mediated by IL28B. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5216545 Tue, 13 Sep 2011 04:00:00 +0100 5216545 http://www.medworm.com/index.php?rid=5216544&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2Fe91wAZDypl8%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001089 by Mwanamvua Boga, Alun Davies, Dorcas Kamuya, Samson M. Kinyanjui, Ester Kivaya, Francis Kombe, Trudie Lang, Vicki Marsh, Bibi Mbete, Albert Mlamba, Sassy Molyneux, Stephen Mulupi, Salim Mwalukore (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5216544 Tue, 13 Sep 2011 04:00:00 +0100 5216544 http://www.medworm.com/index.php?rid=5216543&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FCOFUzVDM0BU%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001068 by Imelda Bates, Richard Phillips, Ruby Martin-Peprah, Gibson Kibiki, Oumar Gaye, Kamija Phiri, Harry Tagbor, Sue Purnell (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5216543 Tue, 13 Sep 2011 04:00:00 +0100 5216543 http://www.medworm.com/index.php?rid=5202036&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FNO-PCdGwKbE%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001090 Conclusions These data suggest that regular, moderate consumption of alcohol at midlife may be related to a modest increase in overall health status among women who survive to older ages. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5202036 Tue, 06 Sep 2011 04:00:00 +0100 5202036 http://www.medworm.com/index.php?rid=5202035&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FmRS4rYiIKVs%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001091 by Stephen S. Lim, Nancy Fullman, Andrew Stokes, Nirmala Ravishankar, Felix Masiye, Christopher J. L. Murray, Emmanuela Gakidou Background Several sub-Saharan African countries have rapidly scaled up the number of households that own insecticide-treated mosquito nets (ITNs). Although the efficacy of ITNs in trials has been shown, evidence on their impact under routine conditions is limited to a few countries and the extent to which the scale-up of ITNs has improved population health remains uncertain. Methods and Findings We used matched logistic regression to assess the individual-level association between household ITN ownership or use in children under 5 years of age and the prevalence of parasitemia among children using six malaria indicator surveys (MIS) and one demographic and health... PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5202035 Tue, 06 Sep 2011 04:00:00 +0100 5202035 http://www.medworm.com/index.php?rid=5202034&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FY5mbhm2N3y4%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001088 by Thomas P. Eisele, Richard W. Steketee (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5202034 Tue, 06 Sep 2011 04:00:00 +0100 5202034 http://www.medworm.com/index.php?rid=5202033&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FQ-JZ6Rcosys%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001087 by Rodrigo Moreno-Serra, Christopher Millett, Peter C. Smith (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5202033 Tue, 06 Sep 2011 04:00:00 +0100 5202033 http://www.medworm.com/index.php?rid=5202032&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FNNlHh8xFY60%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001086 by Peter Lamptey, Michael Merson, Peter Piot, K. Srinath Reddy, Rebecca Dirks (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5202032 Tue, 06 Sep 2011 04:00:00 +0100 5202032 http://www.medworm.com/index.php?rid=5178596&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2F6LxMoyCNSmE%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001084 by The PLoS Medicine Editors (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5178596 Mon, 29 Aug 2011 23:00:00 +0100 5178596 http://www.medworm.com/index.php?rid=5178595&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FtahGLaFnPxg%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001085 by Peter W. Gething, Andrew J. Tatem (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5178595 Mon, 29 Aug 2011 23:00:00 +0100 5178595 http://www.medworm.com/index.php?rid=5178594&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FVq6VLb7kk7I%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001083 Conclusions Results suggest that estimates of population movements during disasters and outbreaks can be delivered rapidly and with potentially high validity in areas with high mobile phone use. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5178594 Mon, 29 Aug 2011 23:00:00 +0100 5178594 http://www.medworm.com/index.php?rid=5178593&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FHWJ6_25CWg4%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001082 Conclusions Rural areas may contribute at least as much to the dissemination of dengue fever as cities. Improving water supply and vector control in areas with a human population density critical for dengue transmission could increase the efficiency of control efforts. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5178593 Mon, 29 Aug 2011 23:00:00 +0100 5178593 http://www.medworm.com/index.php?rid=5178592&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FyaTxEMYmxlA%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001081 by Sara Bennett, Irene Akua Agyepong, Kabir Sheikh, Kara Hanson, Freddie Ssengooba, Lucy Gilson (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5178592 Mon, 29 Aug 2011 23:00:00 +0100 5178592 http://www.medworm.com/index.php?rid=5178591&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2F0TAFttTzX9A%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001080 by Mikkel Zahle Oestergaard, Mie Inoue, Sachiyo Yoshida, Wahyu Retno Mahanani, Fiona M. Gore, Simon Cousens, Joy E. Lawn, Colin Douglas Mathers, on behalf of the United Nations Inter-agency Group for Child Mortality Estimation and the Child Health Epidemiology Reference Group Background Historically, the main focus of studies of childhood mortality has been the infant and under-five mortality rates. Neonatal mortality (deaths (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5178591 Mon, 29 Aug 2011 23:00:00 +0100 5178591 http://www.medworm.com/index.php?rid=5153164&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FzvOTS7NBB1A%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001079 by Lucy Gilson, Kara Hanson, Kabir Sheikh, Irene Akua Agyepong, Freddie Ssengooba, Sara Bennett (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5153164 Mon, 22 Aug 2011 23:00:00 +0100 5153164 http://www.medworm.com/index.php?rid=5153163&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2Fo59rToJRHok%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001078 by Simon Chapman, Matthew C. Farrelly (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5153163 Mon, 22 Aug 2011 23:00:00 +0100 5153163 http://www.medworm.com/index.php?rid=5153162&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FhG5R2U2aljQ%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001077 by Christopher Millett, Jonathan R. Polansky, Stanton A. Glantz (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5153162 Mon, 22 Aug 2011 23:00:00 +0100 5153162 http://www.medworm.com/index.php?rid=5153161&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2F_IsGmU4C5KI%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001076 Conclusions The findings suggest that tobacco company CSR strategies can enable access to and dialogue with policymakers and provide opportunities for issue definition. CSR should therefore be seen as a form of corporate political activity. This underlines the need for broad implementation of Article 5.3 of the Framework Convention on Tobacco Control. Measures are needed to ensure transparency of interactions between all parts of government and the tobacco industry and for policy makers to be made more aware of what companies hope to achieve through CSR. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5153161 Mon, 22 Aug 2011 23:00:00 +0100 5153161 http://www.medworm.com/index.php?rid=5136557&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FJpXvnze-SU0%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001075 Conclusions A lack of financial assistance after reaching the gap spending threshold was associated with a doubling in discontinuing essential medications but not switching drugs in 2006 and 2007. Blunt cost-containment features such as the coverage gap have an adverse impact on drug utilization that may conceivably affect health outcomes. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5136557 Mon, 15 Aug 2011 23:00:00 +0100 5136557 http://www.medworm.com/index.php?rid=5136556&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FIM8FMsCIEVk%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001073 by Kabir Sheikh, Lucy Gilson, Irene Akua Agyepong, Kara Hanson, Freddie Ssengooba, Sara Bennett (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5136556 Mon, 15 Aug 2011 23:00:00 +0100 5136556 http://www.medworm.com/index.php?rid=5115454&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2F3XOS1XCytQo%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001071 by Linda Logdberg (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5115454 Mon, 08 Aug 2011 23:00:00 +0100 5115454 http://www.medworm.com/index.php?rid=5115453&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FZxVWxwv1q3E%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001074 Conclusions In India, sputum smear microscopy remains the most cost-effective diagnostic test available for active TB; efforts to increase access to quality-assured microscopy should take priority. In areas where high-quality microscopy exists and resources are sufficient, MGIT culture is more cost-effective than serology as an additional diagnostic test for TB. These data informed a recently published World Health Organization policy statement against serological tests. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5115453 Mon, 08 Aug 2011 23:00:00 +0100 5115453 http://www.medworm.com/index.php?rid=5115452&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FvWneEjMx9d4%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001062 Conclusions Despite expansion of the literature since 2006, commercial serological tests continue to produce inconsistent and imprecise estimates of sensitivity and specificity. Quality of evidence remains very low. These data informed a recently published World Health Organization policy statement against serological tests. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5115452 Mon, 08 Aug 2011 23:00:00 +0100 5115452 http://www.medworm.com/index.php?rid=5115451&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2Fe9HKZ10RURI%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001072 by Alastair Matheson (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5115451 Mon, 08 Aug 2011 23:00:00 +0100 5115451 http://www.medworm.com/index.php?rid=5092661&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2Fxd8BcraLcEQ%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001070 by Simon Stern, Trudo Lemmens (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5092661 Mon, 01 Aug 2011 23:00:00 +0100 5092661 http://www.medworm.com/index.php?rid=5092660&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FixBHwVfsNeE%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001069 Conclusions There is limited guidance and no consensus regarding the optimal reporting of survey research. The majority of key reporting criteria are poorly reported in peer-reviewed survey research articles. Our findings highlight the need for clear and consistent reporting guidelines specific to survey research. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5092660 Mon, 01 Aug 2011 23:00:00 +0100 5092660 http://www.medworm.com/index.php?rid=5092659&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FHAYqZ8-MccE%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1000444 Conclusions This systematic review and data synthesis indicate that HIV epidemics appear to be emerging among MSM in at least a few MENA countries and could already be in a concentrated state among several MSM groups. There is an urgent need to expand HIV surveillance and access to HIV testing, prevention, and treatment services in a rapidly narrowing window of opportunity to prevent the worst of HIV transmission among MSM in the Middle East and North Africa. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5092659 Mon, 01 Aug 2011 23:00:00 +0100 5092659 http://www.medworm.com/index.php?rid=5067429&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FSpCVJ-gEVM0%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001064 by Carlton A. Evans (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5067429 Mon, 25 Jul 2011 23:00:00 +0100 5067429 http://www.medworm.com/index.php?rid=5067428&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FXUAAtR1k7nk%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001063 by David W. Dowdy, Adithya Cattamanchi, Karen R. Steingart, Madhukar Pai (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5067428 Mon, 25 Jul 2011 23:00:00 +0100 5067428 http://www.medworm.com/index.php?rid=5067427&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FU1ru-qmYrik%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001061 Conclusions The Xpert MTB/RIF test has superior performance for rapid diagnosis of Mycobacterium tuberculosis over existing AFB smear microscopy and other molecular methodologies in an HIV- and TB-endemic region. Its place in the clinical diagnostic algorithm in national health programs needs exploration. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5067427 Mon, 25 Jul 2011 23:00:00 +0100 5067427 http://www.medworm.com/index.php?rid=5067426&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FALlgRA7tZgs%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001067 Conclusions In this population of individuals at high risk of TB, intensive screening using the Xpert MTB/RIF assay increased case detection by 45% compared with smear microscopy, strongly supporting replacement of microscopy for this indication. However, despite the ability of the assay to rapidly detect rifampicin-resistant disease, the specificity for drug-resistant TB was sub-optimal. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5067426 Mon, 25 Jul 2011 23:00:00 +0100 5067426 http://www.medworm.com/index.php?rid=5067425&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2F_0qWHFz3Hgk%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001066 This study examines the trends of 29 key performance indicators over a 5-year period between 2004 and 2008. Methods and Findings Independent evaluations of performance in six domains were conducted annually through 5,500 patient observations and exit interviews and 1,500 provider interviews in >600 facilities selected by stratified random sampling in each province. Generalized estimating equation (GEE) models were used to assess trends in BSC parameters. There was a progressive improvement in the national median scores scaled from 0–100 between 2004 and 2008 in all six domains: patient and community satisfaction of services (65.3–84.5, p (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5067425 Mon, 25 Jul 2011 23:00:00 +0100 5067425 http://www.medworm.com/index.php?rid=5067424&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FZFVh651Ynlw%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001065 by The PLoS Medicine Editors (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5067424 Mon, 25 Jul 2011 23:00:00 +0100 5067424 http://www.medworm.com/index.php?rid=5046399&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FiRTxnrEr8c8%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001060 by Nathan Ford, Edward J. Mills (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5046399 Mon, 18 Jul 2011 23:00:00 +0100 5046399 http://www.medworm.com/index.php?rid=5046398&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FrYHIDERjd2M%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001059 by Stijn Van de Velde, Emmy De Buck, Philippe Vandekerckhove, Jimmy Volmink (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5046398 Mon, 18 Jul 2011 23:00:00 +0100 5046398 http://www.medworm.com/index.php?rid=5046397&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FKxmetT-XgW0%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001056 Conclusions Studies of retention in pre-ART care report substantial loss of patients at every step, starting with patients who do not return for their initial CD4 count results and ending with those who do not initiate ART despite eligibility. Better health information systems that allow patients to be tracked between service delivery points are needed to properly evaluate pre-ART loss to care, and researchers should attempt to standardize the terminology, definitions, and time periods reported. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5046397 Mon, 18 Jul 2011 23:00:00 +0100 5046397 http://www.medworm.com/index.php?rid=5046396&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FCm-UhEDVwZU%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001055 This study evaluated the cost-effectiveness of down-referring stable antiretroviral therapy (ART) patients from a doctor-managed, hospital-based ART clinic to a nurse-managed primary health care facility in Johannesburg, South Africa. Methods and Findings Criteria for down-referral were stable ART (≥11 mo), undetectable viral load within the previous 10 mo, CD4>200 cells/mm3, (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5046396 Mon, 18 Jul 2011 23:00:00 +0100 5046396 http://www.medworm.com/index.php?rid=5025687&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2Fo8HGN50ldDw%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001058 by John P. A. Ioannidis, Alan M. Garber (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5025687 Mon, 11 Jul 2011 23:00:00 +0100 5025687 http://www.medworm.com/index.php?rid=5025686&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2F09Ib04utss4%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001057 by Luis Eduardo Cuevas, Najla Al-Sonboli, Lovett Lawson, Mohammed Ahmed Yassin, Isabel Arbide, Nasher Al-Aghbari, Jeevan Bahadur Sherchand, Amin Al-Absi, Emmanuel Nnamdi Emenyonu, Yared Merid, Mosis Ifenyi Okobi, Juliana Olubunmi Onuoha, Melkamsew Aschalew, Abraham Aseffa, Greg Harper, Rachel Mary Anderson de Cuevas, Sally Jane Theobald, Carl-Michael Nathanson, Jean Joly, Brian Faragher, Stephen Bertel Squire, Andrew Ramsay Background The diagnosis of tuberculosis (TB) in resource-limited settings relies on Ziehl-Neelsen (ZN) smear microscopy. LED fluorescence microscopy (LED-FM) has many potential advantages over ZN smear microscopy, but requires evaluation in the field. The aim of this study was to assess the sensitivity/specificity of LED-FM for the diagnosis of pulmonary TB and whether... PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5025686 Mon, 11 Jul 2011 23:00:00 +0100 5025686 http://www.medworm.com/index.php?rid=5025685&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FKtFkZUPzpPQ%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1000443 by Luis Eduardo Cuevas, Mohammed Ahmed Yassin, Najla Al-Sonboli, Lovett Lawson, Isabel Arbide, Nasher Al-Aghbari, Jeevan Bahadur Sherchand, Amin Al-Absi, Emmanuel Nnamdi Emenyonu, Yared Merid, Mosis Ifenyi Okobi, Juliana Olubunmi Onuoha, Melkamsew Aschalew, Abraham Aseffa, Greg Harper, Rachel Mary Anderson de Cuevas, Kristin Kremer, Dick van Soolingen, Carl-Michael Nathanson, Jean Joly, Brian Faragher, Stephen Bertel Squire, Andrew Ramsay Background More than 50 million people around the world are investigated for tuberculosis using sputum smear microscopy annually. This process requires repeated visits and patients often drop out. Methods and Findings This clinical trial of adults with cough ≥2 wk duration (in Ethiopia, Nepal, Nigeria, and Yemen) compared the sensitivity/specificity of ... PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5025685 Mon, 11 Jul 2011 23:00:00 +0100 5025685 http://www.medworm.com/index.php?rid=5004639&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2F__ZoHpVibE8%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001054 by Nyasha Bakare, Ivor Ralph Edwards, Andy Stergachis, Shanthi Pal, Charles B. Holmes, Marie Lindquist, Chris Duncombe, Alex Dodoo, Joel Novendstern, Jude Nwokike, Ricardo Kuchenbecker, Judith A. Aberg, Veronica Miller, Jur Strobos (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5004639 Mon, 04 Jul 2011 23:00:00 +0100 5004639 http://www.medworm.com/index.php?rid=5004638&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FUCZa_qrJZlo%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001053 by Maria D. Van Kerkhove, Katelijn A. H. Vandemaele, Vivek Shinde, Giovanna Jaramillo-Gutierrez, Artemis Koukounari, Christl A. Donnelly, Luis O. Carlino, Rhonda Owen, Beverly Paterson, Louise Pelletier, Julie Vachon, Claudia Gonzalez, Yu Hongjie, Feng Zijian, Shuk Kwan Chuang, Albert Au, Silke Buda, Gerard Krause, Walter Haas, Isabelle Bonmarin, Kiyosu Taniguichi, Kensuke Nakajima, Tokuaki Shobayashi, Yoshihiro Takayama, Tomi Sunagawa, Jean Michel Heraud, Arnaud Orelle, Ethel Palacios, Marianne A. B. van der Sande, C. C. H. Lieke Wielders, Darren Hunt, Jeffrey Cutter, Vernon J. Lee, Juno Thomas, Patricia Santa-Olalla, Maria J. Sierra-Moros, Wanna Hanshaoworakul, Kumnuan Ungchusak, Richard Pebody, Seema Jain, Anthony W. Mounts, on behalf of the WHO Working Group for Risk Factors for Severe... PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5004638 Mon, 04 Jul 2011 23:00:00 +0100 5004638 http://www.medworm.com/index.php?rid=5004637&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FnL8Fs10BumQ%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001051 Conclusion Early circulation of one influenza strain is associated with a reduced total incidence of the other strains, consistent with the presence of interference between subtypes. Routine ILI and virologic surveillance data can be combined using this new method to predict the relative size of each influenza strain's epidemic by following the change in incidence of a given strain in the context of the incidence of cocirculating strains. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=5004637 Mon, 04 Jul 2011 23:00:00 +0100 5004637 http://www.medworm.com/index.php?rid=4981194&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FLC5FYqhcRng%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001052 Conclusions These observations suggest that handwashing before preparing food is a particularly important opportunity to prevent childhood diarrhea, and that handwashing with water alone can significantly reduce childhood diarrhea. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=4981194 Mon, 27 Jun 2011 23:00:00 +0100 4981194 http://www.medworm.com/index.php?rid=4981193&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FjzFgz9J1LHc%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001050 Conclusions While all three components have contributed to some extent to 30-y changes in TE, changes in EO and PS have accounted for most of the change. These findings suggest a new focus for efforts to reduce energy imbalances in US adults. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=4981193 Mon, 27 Jun 2011 23:00:00 +0100 4981193 http://www.medworm.com/index.php?rid=4981192&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2F4hx0Fztq07Q%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001049 by Gavin Yamey (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=4981192 Mon, 27 Jun 2011 23:00:00 +0100 4981192 http://www.medworm.com/index.php?rid=4981191&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2Fw51YI3tdOpI%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001048 Conclusions Major cardiac complications occur in a substantial proportion of patients with CAP. Physicians and patients need to appreciate the significance of this association for timely recognition and management of these events. Strategies aimed at preventing pneumonia (i.e., influenza and pneumococcal vaccination) in high-risk populations need to be optimized. Further research is needed to understand the mechanisms underlying this association, measure the impact of cardiac complications on other CAP outcomes, identify those patients with CAP at high risk of developing cardiac complications, and design strategies to prevent their occurrence in this population. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=4981191 Mon, 27 Jun 2011 23:00:00 +0100 4981191 http://www.medworm.com/index.php?rid=4958398&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FIl8RtG4vi8E%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001047 by The PLoS Medicine Editors (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=4958398 Mon, 20 Jun 2011 23:00:00 +0100 4958398 http://www.medworm.com/index.php?rid=4958397&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FJL1_idNDROE%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001046 by Anita A. Davies, Rosilyne M. Borland, Carolyn Blake, Haley E. West (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=4958397 Mon, 20 Jun 2011 23:00:00 +0100 4958397 http://www.medworm.com/index.php?rid=4958396&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2F79MXC2GeRfI%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1000442 Conclusions Should H1N1pdm evolve to be more infectious in older adults, average rates of severe disease per infection could be higher in future waves: measuring such changes in severity requires studies similar to that described here. The benefit of effective vaccination against H1N1pdm infection is likely to be substantial for older individuals. Revised pandemic influenza preparedness plans should include prospective serological cohort studies. Many individuals, of all ages, remained susceptible to H1N1pdm after the main 2009 wave in Hong Kong. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=4958396 Mon, 20 Jun 2011 23:00:00 +0100 4958396 http://www.medworm.com/index.php?rid=4930263&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2F-5XaMvQ_bs8%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001045 by Incidence Assay Critical Path Working Group (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=4930263 Mon, 13 Jun 2011 23:00:00 +0100 4930263 http://www.medworm.com/index.php?rid=4930262&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2Fv9nlWyLFl0U%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1000440 Conclusions Our investigation shows a general pattern of SBP progression from childhood in the UK, and suggests possible differences in this pattern during adulthood between a general population and an occupational population. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=4930262 Mon, 13 Jun 2011 23:00:00 +0100 4930262 http://www.medworm.com/index.php?rid=4930261&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FXypzq8Yp9HE%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001044 Conclusions HAART reduced the hazard of mortality in HIV-infected children in Kinshasa by 75%, an estimate that is similar in magnitude but with lower precision than the reported effect of HAART on survival among children in the United States. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=4930261 Mon, 13 Jun 2011 23:00:00 +0100 4930261 http://www.medworm.com/index.php?rid=4930260&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FN_LHDXnZ9cw%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001038 by Zachary Steel, Belinda J. Liddell, Catherine R. Bateman-Steel, Anthony B. Zwi (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=4930260 Mon, 13 Jun 2011 23:00:00 +0100 4930260 http://www.medworm.com/index.php?rid=4909261&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2F4kbSwKAcZgA%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1000438 Conclusions By mapping the distribution of anaemia risk in preschool children adjusted for malnutrition and parasitic infections, we provide a means to identify the geographical limits of anaemia burden and the contribution that malnutrition and parasites make to anaemia. Spatial targeting of ancillary micronutrient supplementation and control of other anaemia causes, such as malaria and helminth infection, can contribute to efficiently reducing the burden of anaemia in preschool children in Africa. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=4909261 Mon, 06 Jun 2011 23:00:00 +0100 4909261 http://www.medworm.com/index.php?rid=4909260&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2F7DhTWf75Nv4%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001042 Conclusions Our data support the hypothesis that influenza influences bacterial disease incidence by enhancing short-term risk of invasion in colonized individuals. The absence of correlation between seasonal waveforms, on the other hand, suggests that bacterial disease transmission is affected to a lesser extent. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=4909260 Mon, 06 Jun 2011 23:00:00 +0100 4909260 http://www.medworm.com/index.php?rid=4909259&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2F5K2qHKUZkIc%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001039 by Abdisalan M. Noor (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=4909259 Mon, 06 Jun 2011 23:00:00 +0100 4909259 http://www.medworm.com/index.php?rid=4909258&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2Fl5wrOW5yLkA%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001043 by Joan Benach, Carles Muntaner, Carlos Delclos, María Menéndez, Charlene Ronquillo (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=4909258 Mon, 06 Jun 2011 23:00:00 +0100 4909258 http://www.medworm.com/index.php?rid=4890046&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2F4l1TLlvdJ8o%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001040 by Caroline Lynch, Cally Roper (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=4890046 Mon, 30 May 2011 23:00:00 +0100 4890046 http://www.medworm.com/index.php?rid=4882137&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2F_iiyGK-eyQg%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1000441 by Saad B. Omer, David Goodman, Mark C. Steinhoff, Roger Rochat, Keith P. Klugman, Barbara J. Stoll, Usha Ramakrishnan Background Infections during pregnancy have the potential to adversely impact birth outcomes. We evaluated the association between receipt of inactivated influenza vaccine during pregnancy and prematurity and small for gestational age (SGA) births. Methods and Findings We conducted a cohort analysis of surveillance data from the Georgia (United States) Pregnancy Risk Assessment Monitoring System. Among 4,326 live births between 1 June 2004 and 30 September 2006, maternal influenza vaccine information was available for 4,168 (96.3%). The primary intervention evaluated in this study was receipt of influenza vaccine during any trimester of pregnancy. The main outcome measures... PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=4882137 Mon, 30 May 2011 23:00:00 +0100 4882137 http://www.medworm.com/index.php?rid=4882136&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FYJryvL6G7Xo%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1000437 Conclusions Subsidizing ACT in the retail sector can significantly increase ACT coverage for reported fevers in rural areas. Further research is needed on the impact and cost-effectiveness of such subsidy programmes at a national scale. Trial Registration Current Controlled Trials ISRCTN59275137 and Kenya Pharmacy and Poisons Board Ethical Committee for Clinical Trials PPB/ECCT/08/07. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=4882136 Mon, 30 May 2011 23:00:00 +0100 4882136 http://www.medworm.com/index.php?rid=4882135&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FH6W9iLDHbcg%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001041 by The PLoS Medicine Editors (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=4882135 Mon, 30 May 2011 23:00:00 +0100 4882135 http://www.medworm.com/index.php?rid=4882134&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2F4l1TLlvdJ8o%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001040 by Caroline Lynch, Cally Roper (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=4882134 Mon, 30 May 2011 23:00:00 +0100 4882134 http://www.medworm.com/index.php?rid=4882133&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2F516EYIHM77A%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1000439 Conclusions There is an association between low haemoglobin concentration and increased mortality. A large proportion of patients with coronary disease have haemoglobin concentrations below the thresholds of risk defined here. Intervention trials would clarify whether increasing the haemoglobin concentration reduces mortality. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=4882133 Mon, 30 May 2011 23:00:00 +0100 4882133 http://www.medworm.com/index.php?rid=4882139&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FmyBuDf2JAcc%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001037 Conclusions Undergraduate medical education provides substantial contact with pharmaceutical marketing, and the extent of such contact is associated with positive attitudes about marketing and skepticism about negative implications of these interactions. These results support future research into the association between exposure and attitudes, as well as any modifiable factors that contribute to attitudinal changes during medical education. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=4882139 Mon, 23 May 2011 23:00:00 +0100 4882139 http://www.medworm.com/index.php?rid=4882138&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FH_LqgfL_Hxw%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1000436 by Gerardo Chowell, Santiago Echevarría-Zuno, Cécile Viboud, Lone Simonsen, James Tamerius, Mark A. Miller, Víctor H. Borja-Aburto Background Mexico's local and national authorities initiated an intense public health response during the early stages of the 2009 A/H1N1 pandemic. In this study we analyzed the epidemiological patterns of the pandemic during April–December 2009 in Mexico and evaluated the impact of nonmedical interventions, school cycles, and demographic factors on influenza transmission. Methods and Findings We used influenza surveillance data compiled by the Mexican Institute for Social Security, representing 40% of the population, to study patterns in influenza-like illness (ILIs) hospi... PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=4882138 Mon, 23 May 2011 23:00:00 +0100 4882138 http://www.medworm.com/index.php?rid=4859862&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2Fqj4a1kKz74E%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001035 by Brian D. Gushulak, Douglas W. MacPherson (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=4859862 Mon, 23 May 2011 23:00:00 +0100 4859862 http://www.medworm.com/index.php?rid=4859861&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FcDouYyFJJo0%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001034 by Cathy Zimmerman, Ligia Kiss, Mazeda Hossain (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=4859861 Mon, 23 May 2011 23:00:00 +0100 4859861 http://www.medworm.com/index.php?rid=4859860&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FmyBuDf2JAcc%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001037 Conclusions Undergraduate medical education provides substantial contact with pharmaceutical marketing, and the extent of such contact is associated with positive attitudes about marketing and skepticism about negative implications of these interactions. These results support future research into the association between exposure and attitudes, as well as any modifiable factors that contribute to attitudinal changes during medical education. Please see later in the article for the Editors' Summary (Source: PLoS Medicine) PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=4859860 Mon, 23 May 2011 23:00:00 +0100 4859860 http://www.medworm.com/index.php?rid=4859859&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FH_LqgfL_Hxw%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1000436 by Gerardo Chowell, Santiago Echevarría-Zuno, Cécile Viboud, Lone Simonsen, James Tamerius, Mark A. Miller, Víctor H. Borja-Aburto Background Mexico's local and national authorities initiated an intense public health response during the early stages of the 2009 A/H1N1 pandemic. In this study we analyzed the epidemiological patterns of the pandemic during April–December 2009 in Mexico and evaluated the impact of nonmedical interventions, school cycles, and demographic factors on influenza transmission. Methods and Findings We used influenza surveillance data compiled by the Mexican Institute for Social Security, representing 40% of the population, to study patterns in influenza-like illness (ILIs) hospi... PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=4859859 Mon, 23 May 2011 23:00:00 +0100 4859859 http://www.medworm.com/index.php?rid=4838023&cid=s_28857_49_f&fid=28857&url=http%3A%2F%2Ffeedproxy.google.com%2F%7Er%2Fplosmedicine%2FNewArticles%2F%7E3%2FKFeAJEauoI4%2Finfo%253Adoi%252F10.1371%252Fjournal.pmed.1001036 by Riitta Luoto, Tarja I. Kinnunen, Minna Aittasalo, Päivi Kolu, Jani Raitanen, Katriina Ojala, Kirsi Mansikkamäki, Satu Lamberg, Tommi Vasankari, Tanja Komulainen, Sirkku Tulokas Background Our objective was to examine whether gestational diabetes mellitus (GDM) or newborns' high birthweight can be prevented by lifestyle counseling in pregnant women at high risk of GDM. Method and Findings We conducted a cluster-randomized trial, the NELLI study, in 14 municipalities in Finland, where 2,271 women were screened by oral glucose tolerance test (OGTT) at 8–12 wk gestation. Euglycemic (n = 399) women with at least one GDM risk factor (body mass index [BMI] ≥25 kg/m2, glucose intolerance or newborn's macrosomia (≥4,500 g) in any earlier pregnancy, family history of diabetes, age ≥... PLoS Medicine journals http://www.medworm.com/rss/comments.php?id=4838023 Mon, 16 May 2011 23:00:00 +0100 4838023