Pediatric Cardiology via MedWorm.com MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Pediatric Cardiology' source. Wed, 08 Feb 2012 09:32:58 +0100 Portal Venous Gas: A Clinical Finding in Obstructed Infracardiac Total Anomalous Pulmonary Venous Connection http://www.medworm.com/index.php?rid=5666982&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj8534789q5j043l3%2F We report a case of obstructive total anomalous pulmonary venous connection (TAPVC) which presented in a way that has not previously been described. An infant with mixed type obstructive TAPVC was found to have pulmonary interstitial emphysema and portal venous gas on a scout radiograph obtained prior to computed tomography scan. The presence of portal venous gas indicated a connection between the pulmonary venous system and the portal venous system infradiaphragmatically. Content Type Journal ArticleCategory Images in Pediatric CardiologyPages 1-3DOI 10.1007/s00246-012-0195-xAuthors Hoyoung Chung, Pediatric Residency Program, Phoenix Children’s Hospital, Phoenix, AZ 85016, USALawrence D. Lilien, Division of Neonatology, St. Joseph’s Hospital and Medical Center, Neonatology A... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5666982 Fri, 03 Feb 2012 17:51:35 +0100 5666982 Improved Closure of Patent Ductus Arteriosus With High Doses of Ibuprofen http://www.medworm.com/index.php?rid=5666983&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr10286w847n40466%2F Abstract  The patent ductus arteriosus (PDA) is associated with various complications of prematurity. Cyclooxygenase-inhibitors are the first-line intervention for closure of the PDA. However, the rates of PDA closure still are unsatisfactory. Therefore, an individual trial was performed by changing the strategy for treating neonates with ibuprofen to induce the closure of PDA. In a retrospective study, patients receiving 20, 10, and 10 mg/kg bodyweight ibuprofen (group 1) were compared by chart review with those receiving 10, 5, 5 mg/kg (group 2). The rate of PDA closure, the incidence of side effects related to the use of ibuprofen, and the need for surgical intervention for closure of the PDA were analyzed. A higher rate of closure after three doses in group 1 ... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5666983 Fri, 03 Feb 2012 17:51:34 +0100 5666983 The Role of Shox2 in SAN Development and Function http://www.medworm.com/index.php?rid=5666984&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F9753355222533280%2F Abstract  Embryonic development is a tightly regulated process, and many families of genes functions to provide a regulatory genetic network to achieve such a program. The homeobox genes are an extensive family that encodes transcription factors with a characteristic 60-amino acid homeodomain. Mutations in these genes or in the encoded proteins might result in structural malformations, physiological defects, and even embryonic death. Mutations in the short-stature homeobox gene (SHOX) is associated with idiopathic short stature in humans, as observed in patients with Turner syndrome and/or Leri-Weill dyschondrosteosis. A closely related human homolog, SHOX2, has not been linked to any syndrome or defect so far. In mice, a SHOX ortholog gene is not present in the genome; howev... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5666984 Fri, 03 Feb 2012 17:51:33 +0100 5666984 The Molecular Autopsy: Should the Evaluation Continue After the Funeral? http://www.medworm.com/index.php?rid=5666985&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg66312kvm15132g5%2F Abstract  Sudden cardiac death (SCD) is one of the most common causes of death in developed countries, with most SCDs involving the elderly, and structural heart disease evident at autopsy. Each year, however, thousands of sudden deaths involving individuals younger than 35 years of age remain unexplained after a comprehensive medicolegal investigation that includes an autopsy. In fact, several epidemiologic studies have estimated that at least 3% and up to 53% of sudden deaths involving previously healthy children, adolescents, and young adults show no morphologic abnormalities identifiable at autopsy. Cardiac channelopathies associated with structurally normal hearts such as long QT syndrome (LQTS), catecholaminergic polymorphic ventricular tachycardia (CPVT), and Br... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5666985 Fri, 03 Feb 2012 17:51:30 +0100 5666985 Automated External Defibrillators and Secondary Prevention of Sudden Cardiac Death Among Children and Adolescents http://www.medworm.com/index.php?rid=5666986&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv23437783m387684%2F This report discusses the outcomes for patients with out-of-hospital cardiac arrest (OHCA) and describes public access defibrillation programs in general and those directed at children and adolescents. In addition, the relatively new concept of cardiopulmonary resuscitation (CPR)–automated external defibrillator (AED) programs directed at schools is discussed. Although limited data are available, some of the preliminary data suggest improved OHCA outcomes associated with CPR-AED programs implemented in schools. These early data provide hope for the future potential reduction in the incidence of sudden cardiac deaths in the school setting, not only among children and adolescents, but also among adults. Content Type Journal ArticleCategory Review ArticlePages 1-5DOI 10.1007/s002... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5666986 Thu, 02 Feb 2012 18:15:58 +0100 5666986 Review of Inhaled Nitric Oxide in the Pediatric Cardiac Surgery Setting http://www.medworm.com/index.php?rid=5659529&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw5x554153267p892%2F Abstract  Surgical intervention for congenital heart disease (CHD) can be complicated by pulmonary hypertension (PH), which increases morbidity, mortality, and medical burden. Consequently, postoperative management of PH is an important clinical consideration to improve outcomes. Inhaled nitric oxide (iNO) is a widely accepted standard of care for PH and has been studied in the context of cardiac surgery for CHD. However, large randomized, double-blind, placebo-controlled, multicenter clinical trials in pediatric patients are limited. This review will provide an overview of the clinical studies in this setting and will discuss general treatment considerations to facilitate a better understanding of the clinical use of iNO for PH after pediatric cardiac surgery. Content ... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5659529 Wed, 01 Feb 2012 17:13:49 +0100 5659529 Primary Cardiac Leiomyoma of the Ventricular Septum: A Rare Form of Pediatric Intracardiac Tumor http://www.medworm.com/index.php?rid=5659528&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fmnvk6248q58u91vv%2F Abstract  A case of ventricular septal tumor diagnosed in 7-month-old boy is reported. An echocardiogram was performed for investigation of a heart murmur in an otherwise healthy infant. He remained asymptomatic, and the tumor had a very slow growth. When the boy was 9 years old, partial surgical excision was performed for right ventricular outflow tract obstruction. Histology showed a primary cardiac leiomyoma. To the authors’ knowledge, a primary cardiac leiomyoma of the ventricular septum has not been reported previously. Content Type Journal ArticleCategory Case ReportPages 1-3DOI 10.1007/s00246-012-0161-7Authors Isabel S. Melo, Serviço de Cardiologia Pediátrica, Hospital de Santa Cruz, Centro Hospitalar de Lisboa Ocidental, Av. Prof. Reinaldo dos Santos, ... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5659528 Wed, 01 Feb 2012 17:13:49 +0100 5659528 Attention-Deficit/Hyperactivity Disorder, Stimulant Therapy, and the Patient with Congenital Heart Disease: Evidence and Reason http://www.medworm.com/index.php?rid=5659527&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Few3385ur5876345r%2F Abstract  Attention-deficit/hyperactivity disorder (ADHD) is the most common neurobehavioral disorder of childhood, and congenital heart disease (CHD) is the most common form of birth defect. Children with CHD are at increased risk for neurodevelopmental disorders such as ADHD. Stimulant medications, specifically methylphenidates and amphetamines, are frequently prescribed and effective in reducing the symptoms of ADHD. Despite their efficacy and long history of use, the safety of these medications has recently come into question due to isolated reports describing sudden unexplained death of children undergoing treatment. This review summarizes the current literature on the cardiovascular risks associated with the use of pharmacologic therapy for ADHD, with an emphasis on p... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5659527 Wed, 01 Feb 2012 17:13:49 +0100 5659527 Prevalence and Spectrum Diseases Predisposing to Sudden Cardiac Death: Are They the Same for Both the Athlete and the Nonathlete? http://www.medworm.com/index.php?rid=5659531&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg526818447218661%2F This report highlights the prevalence and spectrum of SCD-predisposing diseases and how they are affected by athletic participation. In addition, disease-specific guidelines for sports participation are addressed. Content Type Journal ArticleCategory Review ArticlePages 1-8DOI 10.1007/s00246-012-0159-1Authors Anjan S. Batra, Division of Pediatric Cardiology, Children’s Hospital of Orange County, University of California at Irvine, 455 S Main Street, Orange, CA 92868, USASeshadri Balaji, Division of Cardiology, Oregon Health and Science University, Portland, OR, USA Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: Pediatric Cardiology) Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5659531 Tue, 31 Jan 2012 16:45:46 +0100 5659531 Pulmonary Vein Atresia with Severe Contralateral Pulmonary Vein Stenosis in a Child http://www.medworm.com/index.php?rid=5659530&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg270243273142328%2F We present an infant who died due to unilateral right-sided pulmonary vein atresia in conjunction with severe contralateral pulmonary vein stenosis who was diagnosed with the assistance of cardiac computed tomography scanning. Content Type Journal ArticleCategory Images in Pediatric CardiologyPages 1-3DOI 10.1007/s00246-012-0178-yAuthors Jeffrey E. Vergales, Division of Pediatric Cardiology, Department of Pediatrics, University of Virginia Health System, Charlottesville, VA, USAShawn C. West, Division of Pediatric Cardiology, Department of Pediatrics, University of Virginia Health System, Charlottesville, VA, USAAndrew W. Hoyer, Division of Pediatric Cardiology, Department of Pediatrics, University of Virginia Health System, Charlottesville, VA, USA Journal Pediatric Cardiol... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5659530 Tue, 31 Jan 2012 16:45:46 +0100 5659530 Congenital Left Ventricular Diverticulum Diagnosed by Echocardiography http://www.medworm.com/index.php?rid=5659533&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fhv70451h65846130%2F Abstract  Congenital left ventricular diverticulum is a rare cardiac malformation. The incidence of left ventricular diverticulum is reported to be 0.05% of all congenital heart malformations. This case series comprised three infants with the diagnosis of congenital left ventricular diverticulum determined by echocardiography. In addition, two of the three babies also were detected to have other cardiac disease. Echocardiography is a useful tool for diagnosing congenital left ventricular diverticulum. Content Type Journal ArticleCategory Case ReportPages 1-3DOI 10.1007/s00246-012-0153-7Authors Hui Yang, Department of Ultrasound, West China Second University Hospital, West China Medical School, Sichuan Univeisity, 20 ren min nan lu san duan, Chengdu, 610041 ChinaQi Zhu, ... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5659533 Tue, 31 Jan 2012 07:04:43 +0100 5659533 Angina Pectoris with Troponin Increase in Arrhythmogenic Right Ventricle Dysplasia: Case Article and Review of the Literature http://www.medworm.com/index.php?rid=5659532&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2182t820q7668t47%2F Abstract  A 16-year-old Hispanic girl with arrhythmogenic right-ventricle dysplasia (ARVD) presented with angina pectoris and troponin increase on three occasions. There was a family history of sudden cardiac death in a cousin. Her mother was diagnosed with ARVD. The patient herself had a history of nonsustained ventricular tachycardia but did not meet diagnostic criteria for ARVD. Cardiac workup, including serial transthoracic echocardiograms and a coronary angiogram, showed a structurally normal heart without coronary artery stenosis. Results of cardiac magnetic resonance imaging were questionable, but endomyocardial biopsy did not show evidence of viral myocarditis by polymerase chain reaction. Genetic testing confirmed ARVD. Content Type Journal ArticleCategory Case... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5659532 Tue, 31 Jan 2012 07:04:43 +0100 5659532 Implantable Cardioverter-Defibrillators and the Young Athlete: Can the Two Coexist? http://www.medworm.com/index.php?rid=5659534&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq2711tjh876548jq%2F Abstract  Since the incorporation of implantable cardioverter-defibrillators (ICDs) into the management of life-threatening arrhythmias in the 1980s, tremendous advances in device and lead technology have allowed the implantation of ICD systems in younger and smaller patients. The majority of these young patients with “electrical” cardiac disease and a significant number of those with other indications for ICD placement have near normal to normal cardiac function, which has resulted in a large population of young ICD patients with minimal to no symptoms. This population has pushed the boundaries of published guidelines on activity restrictions for the disease state and the presence of an ICD, creating a dilemma for the patient, the family, and the health care team with ... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5659534 Tue, 31 Jan 2012 07:04:41 +0100 5659534 Access to Pediatric Cardiac Care After Health Care Reform in China http://www.medworm.com/index.php?rid=5647505&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk40076633m512018%2F Content Type Journal ArticleCategory Letter to the EditorPages 1-2DOI 10.1007/s00246-012-0177-zAuthors Xuefei Wang, Department of Administration, Children’s Hospital, Zhejiang University School of Medicine, Hangzhou, 310003 ChinaWeize Xu, Department of Cardiothoracic Surgery, Children’s Hospital, Zhejiang University School of Medicine, 57 Zhugan Xiang, Hangzhou, 310003 ChinaQiang Shu, Department of Cardiothoracic Surgery, Children’s Hospital, Zhejiang University School of Medicine, 57 Zhugan Xiang, Hangzhou, 310003 China Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: Pediatric Cardiology) Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5647505 Sat, 28 Jan 2012 16:52:01 +0100 5647505 Ellis-van Creveld Syndrome and Congenital Heart Defects: Presentation of an Additional 32 Cases http://www.medworm.com/index.php?rid=5647506&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F5n6227tt203851th%2F Content Type Journal ArticleCategory EditorialPages 1-2DOI 10.1007/s00246-012-0155-5Authors Matthew J. O’Connor, University of Arkansas for Medical Sciences, Arkansas Children’s Hospital, Little Rock, AR 72202, USAR. Thomas Collins, University of Arkansas for Medical Sciences, Arkansas Children’s Hospital, Little Rock, AR 72202, USA Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: Pediatric Cardiology) Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5647506 Fri, 27 Jan 2012 17:56:46 +0100 5647506 Functional Echocardiographic Assessment of Myocardial Performance in Anemic Premature Infants: A Pilot Study http://www.medworm.com/index.php?rid=5638314&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa4l3l886821x4640%2F In this study, 32 anemic premature infants had serial echocardiographic assessment of left ventricular (LV) systolic performance, LV preload, and afterload immediately before, within 48 h, and up to 120 h after the transfusion of pRBCs. Pretransfusional evaluations also were compared with similar assessments of 71 nonanemic inpatient premature infants analogous for sex, gestational age at birth, and postnatal age. Left ventricular systolic performance was estimated from fractional shortening, LV output, and LV myocardial performance index (LVMPI). The LV preload was estimated from the LV end-diastolic dimension and the ratio of left atrium-to-aortic root dimension (LA/Ao ratio). The LV afterload was estimated from end-systolic wall stress. The LVMPI was found to decrease wi... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5638314 Tue, 24 Jan 2012 18:09:39 +0100 5638314 From Other Journals http://www.medworm.com/index.php?rid=5619893&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh66x335m54621830%2F Content Type Journal ArticleCategory From Other JournalsPages 1-3DOI 10.1007/s00246-012-0156-4Authors Sanjiv Gandhi, 1507 W. Harrison Street, Chicago, IL 60607, USAOmar M. Khalid, 1507 W. Harrison Street, Chicago, IL 60607, USA Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: Pediatric Cardiology) Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5619893 Wed, 18 Jan 2012 06:52:07 +0100 5619893 Upcoming Events in Pediatric Cardiology http://www.medworm.com/index.php?rid=5619892&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2458042818206667%2F Content Type Journal ArticleCategory Upcoming EventsPages 1-1DOI 10.1007/s00246-012-0157-3 Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: Pediatric Cardiology) Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5619892 Wed, 18 Jan 2012 06:52:07 +0100 5619892 Outcome of Biventricular Repair in Infants With Multiple Left Heart Obstructive Lesions http://www.medworm.com/index.php?rid=5494788&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg6k2m141w232n01g%2F This study sought to assess the mortality and morbidity of patients with LHL after biventricular repair and to determine the growth of the left-sided cardiac structures. Retrospective analysis of 39 consecutive infants with LHL who underwent biventricular repair was performed. The median age at surgery was 7 days (range 1–225 days), and the median follow-up period was 34 months (range 1–177 months). Between diagnosis and the end of the follow-up period, the size of the aortic annulus (z-score −4.1 ± 2.8 vs. −0.1 ± 2.7) and the LV (LV end-diastolic diameter z-score −1.7 ± 2.8 vs. 0.21 ± 1.7) normalized. During the follow-up period, 23 patients required 39 reinterventions (62%) consisting of redo surgery for 21 pa... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5494788 Sat, 10 Dec 2011 16:56:13 +0100 5494788 From Other Journals http://www.medworm.com/index.php?rid=5486643&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F28l337rg84733635%2F Content Type Journal ArticleCategory From Other JournalsPages 1-3DOI 10.1007/s00246-011-0151-1Authors Sanjiv Gandhi, 1507 W. Harrison Street, Chicago, IL 60607, USAOmar M. Khalid, 1507 W. Harrison Street, Chicago, IL 60607, USA Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: Pediatric Cardiology) Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5486643 Wed, 07 Dec 2011 16:44:26 +0100 5486643 Upcoming Events in Pediatric Cardiology http://www.medworm.com/index.php?rid=5486644&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv58765050h423t4w%2F Content Type Journal ArticleCategory Upcoming EventsPages 1-1DOI 10.1007/s00246-011-0152-0 Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: Pediatric Cardiology) Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5486644 Tue, 06 Dec 2011 17:04:29 +0100 5486644 Lost Unilateral Capillary Perfusion During Nonpulsatile Pulmonary Circulation: Successful Recovery by Oral Sildenafil http://www.medworm.com/index.php?rid=5457243&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F571600011p182344%2F Abstract  Good status of pulmonary perfusion is essential for a successful outcome after the Fontan procedure. Increased pulmonary pressure and vascular resistance, small size of the pulmonary arteries, and significant branch stenoses reflect some of the main problems causing failing Fontan circulation. Here we report a child who underwent a staged Fontan procedure with subsequent subtotal loss of the left-sided pulmonary perfusion, although branch stenosis was successfully treated by stent implantation. Oral sildenafil caused restoration of the capillary vascular bed, improved left-sided lung perfusion, and resulted in significant clinical benefit. Content Type Journal ArticleCategory Case ReportPages 1-5DOI 10.1007/s00246-011-0136-0Authors Levent Celik, Department f... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5457243 Sat, 26 Nov 2011 16:46:33 +0100 5457243 Ischemic Stroke Caused by Paradoxical Embolism After an Unsuccessful Transcatheter Atrial Septal Defect Closure Procedure: A Word of Caution http://www.medworm.com/index.php?rid=5457244&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc6687m6287078222%2F Abstract  Transcatheter device closure of atrial septal defect (ASD) has become a well-accepted alternative to surgical repair. Serious complications of transcatheter ASD closure are rare, but when they occur, devastating consequences may result. Herein, we present the case of a 4-year-old girl who had an ischemic stroke caused by a presumptive paradoxical embolism after an unsuccessful transcatheter ASD procedure and in whom subsequent venous color Doppler showed deep venous thrombosis (DVT) of the right lower extremity. The risk factors that predisposed to paradoxical cerebral embolism and DVT in this patient are discussed, and the literature is reviewed. Content Type Journal ArticleCategory Case ReportPages 1-4DOI 10.1007/s00246-011-0150-2Authors Zhen-fei Fang, Dep... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5457244 Sat, 26 Nov 2011 16:46:31 +0100 5457244 Cor Triatriatum With Partial Anomalous Pulmonary Venous Return: A Rare Case of Parallel Obstruction and Successful Staged Treatment http://www.medworm.com/index.php?rid=5449662&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F4463t7416300774p%2F We present a case of such rare anatomy with multilevel obstruction that presented in infancy as cardiogenic shock. The patient underwent staged treatment with extracorporeal membrane oxygenation stabilization, catheter-based balloon dilatation of the cor triatriatum and atrial septostomy, followed by definitive surgical repair, with excellent result. Content Type Journal ArticleCategory Case ReportPages 1-3DOI 10.1007/s00246-011-0148-9Authors Ofer Schiller, Division of Cardiology, Children’s National Medical Center, Washington, DC 20010, USAKristin M. Burns, Division of Cardiology, Children’s National Medical Center, Washington, DC 20010, USAPranava Sinha, Department of Cardiovascular Surgery, Children’s National Medical Center, Washington, DC 20010, USASusan D. Cummings, D... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5449662 Thu, 24 Nov 2011 17:45:08 +0100 5449662 Feasibility of Improving the Motor Development of Toddlers With Congenital Heart Defects Using a Home-Based Intervention http://www.medworm.com/index.php?rid=5449663&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk208u583r4t46001%2F This study investigated the feasibility of administering motor assessments, delivering rehabilitation via parent-led activities, and enhancing motor function in children with complex congenital heart defects. Gross and fine motor development were evaluated in 20 toddlers ages 12 to 26 months after either a superior cavopulmonary connection (SCPC) procedure or an arterial switch operation (ASO) using the Peabody developmental scale, version 2 (PDMS-2). Feasibility of assessment and program delivery were examined using open-ended interviews with parents. The ASO group scored consistently higher than the SCPC group in every subscore of the PDMS-2 (ASO gross motor quotient, 96.78 ± 7.396 vs SCPC gross motor quotient, 77.56 ± 7.715 [P < 0.001]; ASO f... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5449663 Thu, 24 Nov 2011 17:45:06 +0100 5449663 Update on the Amplatzer Duct Occluder: A 10-Year Experience in Asia http://www.medworm.com/index.php?rid=5440582&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk6607n2534045207%2F Abstract  Few data exist regarding the efficacy and safety of the Amplatzer ductal occluder (ADO) type 1 device in the Asian region. This retrospective study, conducted between August 2001 and April 2011, attempted device placement for 231 patients (165 females and 66 males) with a median age of 7.4 years (range, 3 months to 64 years) and an average weight of 19.4 kg (range, 4.1–81.0 kg). Among the patients in this study, 66 (28.6%) had pulmonary hypertension, ten (4.3%) had trisomy 21, and eight (3.5%) had other congenital cardiac anomalies. The mean narrowest patent ductus arteriosus (PDA) diameter was 4.2 mm (range, 1.3–10 mm), and the ampulla size was 9.6 mm (range, 4–20 mm). Successful implantation was achieved for 229 ... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5440582 Mon, 21 Nov 2011 17:53:35 +0100 5440582 Assessment of Risk Factors for Korean Children with Kawasaki Disease http://www.medworm.com/index.php?rid=5440583&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj511434125664771%2F Abstract  Kawasaki disease (KD) is the most common cause of acquired heart disease in children. Intravenous immunoglobulin (IVIG) is the standard therapy for KD, but more than 10% of KD patients do not respond to IVIG and are at high risk for the development of coronary artery lesions (CALs). To identify clinical and genetic risk factors associated with CAL development and IVIG nonresponsiveness, this study analyzed the clinical data for 478 Korean KD patients. Multivariate logistic regression analysis showed that incomplete KD, IVIG nonresponse, fever duration of 7 days or longer, and the CC/AC genotypes of the rs7604693 single nucleotide polymorphism (SNP) in the PELI1 gene were significantly associated with the development of CALs, with odds ratios (ORs) ranging from... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5440583 Mon, 21 Nov 2011 17:53:34 +0100 5440583 A Novel GATA4 Loss-of-Function Mutation Associated With Congenital Ventricular Septal Defect http://www.medworm.com/index.php?rid=5440584&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj87007550573k8h7%2F In this study, the entire coding region of GATA4, a gene encoding a zinc finger transcription factor essential for normal cardiac morphogenesis, was sequenced in 160 unrelated patients with VSD. The available relatives of the index patient harboring the identified mutation and 200 unrelated control individuals were subsequently genotyped. The disease-causing potential of a sequence alteration was evaluated by MutationTaster, and the functional effect of the mutation was characterized using a luciferase reporter assay system. As a result, a novel heterozygous GATA4 variation, p.R43W, was identified in a proband with VSD, that was absent in control subjects. Genetic analysis of the family members of the variation carrier showed that the substitution co-segregated with VSD. The p.R43W va... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5440584 Sat, 19 Nov 2011 16:54:34 +0100 5440584 Outcomes of Infants Undergoing Superior Cavopulmonary Connection in the Presence of Ventricular Dysfunction http://www.medworm.com/index.php?rid=5431570&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr456314482515251%2F Abstract  Outcomes in patients with ventricular dysfunction undergoing superior cavopulmonary connection (SCPC) are not well known. We reviewed records of patients undergoing SCPC at our center from December 2005 to October 2009 and studied those whose pre-SCPC echocardiograms demonstrated at least moderate systemic ventricular dysfunction. Of the 213 patients undergoing SCPC, 19 (9%) met inclusion criteria. Diagnoses were hypoplastic left heart syndrome (n = 18) and rightward unbalanced atrioventricular canal with pulmonary stenosis (n = 1). In those surviving >2 months after SCPC, ventricular function was assessed by echocardiography 4.9 (range 3.5 to 9.7) months after SCPC and was improved in ten of 17 (59%), unchanged in six of 17 (35%), and wo... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5431570 Fri, 18 Nov 2011 17:29:29 +0100 5431570 Use of Troponin as a Screen for Chest Pain in the Pediatric Emergency Department http://www.medworm.com/index.php?rid=5421831&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb87jl9r336287472%2F Abstract  Troponin levels are commonly employed in the assessment of adults presenting with chest pain or concern for coronary ischemia. However, the utility of troponin measurements in children is not well defined. The purpose of this study was to review the use and clinical yield of serum troponin assay in a large pediatric emergency department (ED). We identified all patients <22 years of age, not previously known to have cardiac disease, who presented with chest pain and whose troponin levels were evaluated in our pediatric ED during a 7-year period. Test results were correlated to patient factors, such as chief complaint, cardiac history, diagnostic workup, and discharge diagnoses. Of the 212 study patients who presented with chest pain, troponin levels we... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5421831 Wed, 16 Nov 2011 16:48:05 +0100 5421831 Environmental Factors and Rheumatic Heart Disease in Fiji http://www.medworm.com/index.php?rid=5386017&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx10363161374w528%2F Abstract  Rheumatic heart disease (RHD) is an important cause of cardiac morbidity and mortality globally, particularly in the Pacific region. Susceptibility to RHD is thought to be due to genetic factors that are influenced by environmental factors, such as crowding and poverty. However, there are few data relating to these environmental factors in the Pacific region. We conducted a case-control study of 80 cases of RHD with age- and sex-matched controls in Fiji using a questionnaire to investigate associations of RHD with a number of environmental factors. There was a trend toward increased risk of RHD in association with poor-quality housing and lower socioeconomic status, but only one factor, maternal unemployment, reached statistical significance (OR 2.6, 95% confidenc... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5386017 Sat, 05 Nov 2011 17:08:47 +0100 5386017 Age- and Chamber-Specific Differences in Oxidative Stress After Ischemic Injury http://www.medworm.com/index.php?rid=5386019&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fml006413410r6114%2F Abstract  Each year, tens of thousands of children undergo cardiopulmonary bypass (CPB) to correct congenital heart defects. Although necessary for surgery, CPB involves stopping the heart and exposing it to ischemic conditions. On reoxygenation, the heart can experience effects similar to that of acute myocardial infarction. Although much is known about adult injury, little is known about the effects of global ischemia on newborn ventricles. We studied newborn (2 to 4 days old) and adult (>8 weeks old) rabbit hearts subjected to ischemia–reperfusion (30 min of ischemia and 60 min of reperfusion). Our data demonstrated chamber- and age-specific changes in oxidative stress. During ischemia, hydrogen peroxide (H2O2) increased in both right-ventricular ... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5386019 Sat, 05 Nov 2011 17:08:45 +0100 5386019 Improvement and Defervescence of Persistent Fever After One Course of Intravenous Immunoglobulin in a Patient With Bacterial Infective Endocarditis http://www.medworm.com/index.php?rid=5386018&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw801280537156vm1%2F Content Type Journal ArticleCategory Case ReportPages 1-3DOI 10.1007/s00246-011-0138-yAuthors Musaab Ramsi, Floating Hospital for Children, Tufts Medical Center, Tufts University School of Medicine, Boston, MA, USARashed Durgham, Floating Hospital for Children, Tufts Medical Center, Tufts University School of Medicine, Boston, MA, USAMichael de Moor, Floating Hospital for Children, Tufts Medical Center, Tufts University School of Medicine, Boston, MA, USA Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: Pediatric Cardiology) Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5386018 Sat, 05 Nov 2011 17:08:45 +0100 5386018 From Other Journals http://www.medworm.com/index.php?rid=5360198&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk7865v0h5333h573%2F Content Type Journal ArticleCategory From Other JournalsPages 1-2DOI 10.1007/s00246-011-0140-4Authors Sanjiv Gandhi, 1507 W. Harrison Street, Chicago, IL 60607, USAOmar M. Khalid, 1507 W. Harrison Street, Chicago, IL 60607, USA Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: Pediatric Cardiology) Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5360198 Fri, 28 Oct 2011 17:16:11 +0100 5360198 Upcoming Events in Pediatric Cardiology http://www.medworm.com/index.php?rid=5360199&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft32w16775m820405%2F Content Type Journal ArticleCategory Upcoming EventsPages 1-1DOI 10.1007/s00246-011-0141-3 Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: Pediatric Cardiology) Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5360199 Fri, 28 Oct 2011 17:16:09 +0100 5360199 Comparison of Long-Term Clinical Outcomes and Costs Between Video-Assisted Thoracoscopic Surgery and Transcatheter Amplatzer Occlusion of the Patent Ductus Arteriosus http://www.medworm.com/index.php?rid=5360200&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa3nl353371k22x54%2F This study enrolled 294 patients with isolated patent ductus arteriosus (PDA) from April 2002 to April 2007, and 290 of these patients were followed up until April 2010. Of the 294 patients, 196 underwent VATS and 98 accepted TAO for PDA closure. The two groups were similar in terms of demographics and preoperative clinical characteristics. No cardiac deaths occurred in either group. All the patients in the VATS group had successful PDA closure, and 94 patients (94/98, 95.9%) in the TAO group had successful PDA occlusion. The incidence of acute procedure-related complications recorded was 1.5% in the VATS group compared with 10.2% in TAO group (P < 0.05). The cost per patient was $1,309.40 ± $312.20 in the VATS group and $3,415.80 ± $637.30 in the TA... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5360200 Fri, 28 Oct 2011 17:16:08 +0100 5360200 Various Modalities for Evaluation of a Fused Heart in Conjoined Twins http://www.medworm.com/index.php?rid=5323823&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ffu3g5t7368278030%2F We report a series of 20 sets of thoracopagus conjoined twins as well as the results of a PubMed database literature review literature from 1982 to 2009. Twenty sets of fused-heart thoracopagus conjoined twins were evaluated by echocardiography, cardiac catheterization, magnetic resonance image (MRI), and three-dimensional computed tomography angiography (3D-CTA). Imaging results were compared to findings at surgery or autopsy. All sets of conjoined twins underwent postnatal echocardiography; 11 sets (55%) underwent cardiac catheterization; 4 sets (20%) underwent MRI; and 1 set (5%) underwent 3D-CTA. All intracardiac anatomy (ICA) was identified by echocardiography. Cardiac catheterization, MRI, and 3D-CTA were able to identify extracardiac vascular structures as well as the ICA. 3D-... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5323823 Sat, 15 Oct 2011 05:52:28 +0100 5323823 Transseptal Catheter Decompression of the Left Ventricle During Extracorporeal Membrane Oxygenation http://www.medworm.com/index.php?rid=5314214&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl0122242j2mn8305%2F We present the case of a 13-year-old girl who presented with cardiogenic shock. VA-ECMO was initiated, but after 6 days, severe left-ventricular distension resulted in decreased VA-ECMO flows. With guidance by bedside transesophageal echocardiography, a percutaneous atrial transseptal cannula was placed and connected to the venous circuit, thus decompressing the left ventricle. The patient improved, was weaned from VA-ECMO 5 days later, and was discharged from the hospital. Bedside transseptal catheter insertion is an effective method of left-ventricular decompression. Content Type Journal ArticleCategory Case ReportPages 1-3DOI 10.1007/s00246-011-0113-7Authors Michael F. Swartz, Department of Surgery, Strong Memorial Hospital, University of Rochester, Rochester, NY 14... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5314214 Sat, 08 Oct 2011 15:44:39 +0100 5314214 Hypoplastic Left Heart Syndrome, Restrictive Patent Foramen Ovale, and Pulmonary Valve Stenosis: An Unusual Combination http://www.medworm.com/index.php?rid=5314215&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F4wt8526u07667051%2F Abstract  An infant presented with a rare combination of hypoplastic left heart syndrome, restricted patent foramen ovale, and moderately dysplastic pulmonary valve. In preparation for heart transplantation, bilateral pulmonary artery banding was performed to protect the pulmonary vasculature. Content Type Journal ArticleCategory Case ReportPages 1-3DOI 10.1007/s00246-011-0119-1Authors Sanjeev Aggarwal, Department of Pediatrics, Children’s Hospital of Michigan, 3901 Beaubien Boulevard, Detroit, MI 48201, USARalph E. Delius, Department of Cardiovascular Surgery, Children’s Hospital of Michigan, 3901 Beaubien Boulevard, Detroit, MI 48201, USAHenry L. Walters, Department of Cardiovascular Surgery, Children’s Hospital of Michigan, 3901 Beaubien Boulevard, Detroit, MI 4... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5314215 Sat, 08 Oct 2011 15:44:38 +0100 5314215 Heart Rate Variability in Children With Fontan Circulation: Lateral Tunnel and Extracardiac Conduit http://www.medworm.com/index.php?rid=5304256&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu35450u42t716h42%2F This study aimed to investigate HRV in a cohort of children with univentricular hearts, focusing on the relation between HRV and surgical procedure. For 112 children with Fontan circulation, HRV was analyzed using power spectral analysis. Spectral power was determined in three regions: very-low-frequency (VLF), low-frequency (LF), and high-frequency (HF) regions. Patients were compared with 66 healthy controls subject. Patients with LT were compared with patients who had EC. The children with Fontan circulation showed a significantly reduced HRV including total power (P < 0.0001), VLF (P < 0.0001), LF (P < 0.0001), and HF (P = 0.001) compared with the control subjects. The LT and EC patients did not differ significantly. Reduced HRV was ... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5304256 Fri, 07 Oct 2011 15:59:49 +0100 5304256 Right Ventricle Myocardial Perfusion Scintigraphy: Feasibility and Expected Values in Children http://www.medworm.com/index.php?rid=5296812&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Frp6154232r751823%2F Abstract  Stress myocardial perfusion scintigraphy imaging (SMPSI) has important applications for evaluating coronary disease and ventricular function. Studies consistently focus on the left ventricle (LV), with no normal right ventricle (RV) data available. This study sought to evaluate the feasibility of RV perfusion with technetium (Tc-99m) sestamibi using a low radiotracer dose for children free of coronary artery (CA) anomalies and to determine its normal pattern. Patients with a history of Kawasaki disease who showed no coronary complications on selective angiography or no LV perfusion defects on SMPSI were studied at rest and during an exercise challenge. The RV uptake counts were compared with those for different segments of the LV, and multiple ratios of the uptake... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5296812 Tue, 04 Oct 2011 05:52:45 +0100 5296812 Usefulness of Doppler Derived End Diastolic Flow Gradient Across the Patent Ductus Arteriosus in Selecting Coils for Ductal Occlusion http://www.medworm.com/index.php?rid=5296813&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F11h3n74642244703%2F Abstract  Transcatheter closure of patent ductus arteriosus (PDA) with coils is accepted as an alternative to surgical ligation. We evaluated whether flow gradient across PDA, obtained by Doppler echocardiography, can aid in selecting coils for percutaneous ductal occlusion. 79 consecutive patients with PDA, who underwent successful percutaneous coil occlusion were retrospectively reviewed. Patients with other structural heart disease and pulmonary hypertension with right-to-left shunt were excluded. Echocardiogram and cardiac catheterization were done in all patients. Gianturco (Occluding Spring Emboli; Cook, Bloomington, IN) non-detachable coils of 0.038 and 0.052-inch core sizes were used for ductal occlusion. Trough diastolic gradient was correlated with the size and th... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5296813 Tue, 04 Oct 2011 05:52:44 +0100 5296813 Heterogeneity of Ventricular Repolarization in Newborns With Severe Aortic Coarctation http://www.medworm.com/index.php?rid=5296814&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fqq51044u1238632j%2F Abstract  Sudden death is a possible occurrence for newborns younger than 1 year with severe aortic coarctation (CoA) before surgical correction. Basic research and animal experiments have shown electrophysiologic changes during mechanical ventricular pressure overload. The current study aimed to evaluate the effect of severe CoA on the heterogeneity of ventricular repolarization by examining corrected QT and JT interval dispersion (respectively, QTc-D and JTc-D) and electrocardiographic parameters of spatial heterogeneity of ventricular repolarization in newborns with no associated congenital cardiac malformations. The study enrolled 30 isolated severe CoA neonates (age, 45 ± 15 days; 17 males) with normal size and wall thickness of the left ventricle ... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5296814 Tue, 04 Oct 2011 05:52:43 +0100 5296814 Atypical Partial Anomalous Pulmonary Venous Drainage of the Left Upper Pulmonary Vein Through a Compressed Vertical Vein Between the Aorta and the Pulmonary Artery http://www.medworm.com/index.php?rid=5296815&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy67836458j685685%2F Content Type Journal ArticleCategory Images in Pediatric CardiologyPages 1-2DOI 10.1007/s00246-011-0134-2Authors Habiba Mizouni, Department of Radiology, La Rabta University Hospital, Jebbari, 1007 Tunis, TunisiaMonia Attia, Department of Radiology, La Rabta University Hospital, Jebbari, 1007 Tunis, TunisiaJalel Zaidi, Department of Cardiovascular Surgery, La Rabta University Hospital, Jebbari, 1007 Tunis, TunisiaEmna Menif, Department of Radiology, La Rabta University Hospital, Jebbari, 1007 Tunis, Tunisia Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: Pediatric Cardiology) Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5296815 Tue, 04 Oct 2011 05:52:42 +0100 5296815 Plasmin Generation and Fibrinolysis in Pediatric Patients Undergoing Cardiopulmonary Bypass Surgery http://www.medworm.com/index.php?rid=5285353&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fw25423k0316nt064%2F This study establishes the foundation for future studies in this area, particularly those focusing on clinical outcomes after CPB surgery. Content Type Journal ArticleCategory Original ArticlePages 1-6DOI 10.1007/s00246-011-0122-6Authors Vera Ignjatovic, Murdoch Childrens Research Institute, Flemington Road, Parkville, VIC 3052, AustraliaAparajith Chandramouli, Department of Clinical Haematology, Royal Children’s Hospital, Melbourne, AustraliaJenny Than, Department of Clinical Haematology, Royal Children’s Hospital, Melbourne, AustraliaRobyn Summerhayes, Murdoch Childrens Research Institute, Flemington Road, Parkville, VIC 3052, AustraliaFiona Newall, Murdoch Childrens Research Institute, Flemington Road, Parkville, VIC 3052, AustraliaSteve Horton, Department of Cardiac Surgery... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5285353 Sun, 02 Oct 2011 05:50:11 +0100 5285353 Changes in Hemodynamic Parameters and Cerebral Saturation During Supraventricular Tachycardia http://www.medworm.com/index.php?rid=5285354&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fc42n23u50347g1n4%2F This study aimed first to determine the hemodynamic changes associated with electrophysiology testing for SVT and second to determine whether the hemodynamic changes are associated with similar changes in the cerebral saturation as determined by NIRS. The study enrolled 30 patients 5–20 years of age with a history of SVT who underwent an EPS. The demographic data included age, gender, weight, height, and type of SVT. Hemodynamic data (invasive blood pressure and heart rate), NIRS, bispectral index (BIS), end-tidal carbon dioxide, and pulse oximetry were collected before and during three episodes of induced SVT. The linear correlation coefficient (r) was measured to calculate the relationship of the changes in systolic blood pressure (SBP), diastolic blood pressure (DBP), and m... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5285354 Sun, 02 Oct 2011 05:46:08 +0100 5285354 Epidemiologic Survey of Kawasaki Disease in Jilin from 1999 Through 2008 http://www.medworm.com/index.php?rid=5285355&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2166964450k31320%2F In conclusion, incidences of KD increased in Jilin Province. Age and gender distribution shared similarities with previous reports, and the seasonal distribution was different. Age and lower serum albumin were the most important risk factors of coronary arterial lesions (CAL) in KD. In addition, patients treated with steroids also had a possible heightened risk of contracting CAL. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00246-011-0121-7Authors Xiaomei Zhang, Department of Pediatrics, The First Hospital of Jilin University, 71 Xin Min Street, Changchun, 130021 Jilin, ChinaZhen Zhang, Department of Pediatrics, The First Hospital of Jilin University, 71 Xin Min Street, Changchun, 130021 Jilin, ChinaShicheng Liu, Department of Pediatrics, The First ... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5285355 Sat, 01 Oct 2011 06:46:41 +0100 5285355 Multiple External Electrical Cardioversions for Refractory Neonatal Atrial Flutter http://www.medworm.com/index.php?rid=5285356&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq111v46054228k42%2F This report describes a case of atrial flutter in a fetal/neonatal patient who did not respond to adenosine, a propafenone bolus, and three electrical external cardioversions. A fourth direct current cardioversion after propafenone premedication resolved the atrial flutter. The arrhythmia did not recur with propafenone therapy during a 12-month follow-up period. Content Type Journal ArticleCategory Case ReportPages 1-3DOI 10.1007/s00246-011-0131-5Authors Simone Gulletta, Department of Cardiology, San Raffaele University Hospital, Milan, ItalyRosanna Rovelli, Department of Pediatrics, San Raffaele University Hospital, Milan, ItalyRossana Fiori, Department of Anesthesia and Intensive Care, San Raffaele University Hospital, Milan, ItalyPaolo Della Bella, Department of Cardiology, San... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5285356 Sat, 01 Oct 2011 06:46:40 +0100 5285356 Transcatheter Closure of Ruptured Sinus of Valsalva Aneurysm Into the Left Ventricle: A Retrograde Approach http://www.medworm.com/index.php?rid=5285358&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg683w76884w78w8p%2F This report presents a rare case of a patient with treated infective endocarditis who had a patent ductus arteriosus (PDA), a coronary cameral fistula, and a ruptured ASOV (RASOV) into the left ventricle (LV). Successful transcatheter closure of the ruptured ASOV and the other two lesions was performed using three Amplatzer duct occluders (AGA Medical Corporation, Golden Valley, MN, USA). Content Type Journal ArticleCategory Case ReportPages 1-4DOI 10.1007/s00246-011-0127-1Authors Anurakti Srivastava, Department of Pediatric Cardiology, Apollo Health City, Jubilee Hills, Hyderabad, IndiaAnil Sivadasan Radha, Department of Pediatric Cardiology, Apollo Health City, Jubilee Hills, Hyderabad, India Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: ... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5285358 Fri, 30 Sep 2011 06:29:07 +0100 5285358 Short- and Mid-Term Outcomes of Total Correction of Taussig–Bing Anomaly http://www.medworm.com/index.php?rid=5285357&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F10514418m76w4qjv%2F This study evaluates our experience and outcomes of total correction of DORV-TB anomaly at King Abdulaziz Cardiac Center. We conducted a retrospective study for all cases of TB anomaly repaired between June 2001 and April 2009. Patients were divided into two groups: Group A included patients repaired with arterial switch operation, and group (B) included patients repaired with Rastelli procedure. Thirteen patients with TB anomaly underwent total correction. There were 5 male (38%) and 8 female (62%) patients. Mean age and weight at surgery were 6.8 ± 6 weeks and 3.6 ± 0.7 kg, respectively. Of the 13 patients, 9 (69%) were in group A, and 4 (31%) were in group B. Aortic arch abnormalities were present in 9 patients (69%); abnormal coronary artery patter... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5285357 Fri, 30 Sep 2011 06:29:07 +0100 5285357 Conjoined Hearts in Thoracopagus Twins http://www.medworm.com/index.php?rid=5285360&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F03872r527qu140tq%2F This study aimed to identify the anatomic and pathologic structural cardiac abnormalities in conjoined twins and to focus on those that have prevented the successful separation of conjoined hearts. A retrospective review was undertaken to examine consecutive cases of thoracopagus conjoined twins with conjoined hearts evaluated at The Children’s Hospital of Philadelphia from 1 January 1980 through 6 October 2008. The records included autopsy and surgical findings as well as clinical reports. The study group included nine sets of conjoined twins with a mean gestational age at birth of 33.8 ± 5.5 weeks. Three twin pairs were stillborn. Five twin pairs died afterward. One pair died of cardiopulmonary failure. The median age at death was 22 days (range, 0–345&nbsp... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5285360 Fri, 30 Sep 2011 06:29:06 +0100 5285360 Influence of Fetal Diagnosis on the Clinical Presentation of a Vascular Ring http://www.medworm.com/index.php?rid=5285359&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F8nq6u457k5707182%2F Abstract  A fetus had a diagnosis of a vascular ring formed by a right aortic arch with an aberrant left subclavian artery. The infant experienced isolated dysphagia and vomiting 3 months after birth. Magnetic resonance imaging (MRI) confirmed the vascular ring and demonstrated profound, isolated esophageal dilation with normal airways. The severity of postnatal symptoms due to a vascular ring is difficult to determine in utero. Expectant management of the lesion is necessary, and use of MRI as the imaging method allows for both confirmation of the diagnosis and evaluation of the airway and esophagus while avoiding radiation. Content Type Journal ArticleCategory Case ReportPages 1-3DOI 10.1007/s00246-011-0129-zAuthors Laura J. Olivieri, Division of Cardiology, W3-... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5285359 Fri, 30 Sep 2011 06:29:06 +0100 5285359 The Cause of B-Type Natriuretic Peptide Elevation and the Dose-Dependent Effect of Angiotensin-Converting Enzyme Inhibitor on Patients Late After Tetralogy of Fallot Repair http://www.medworm.com/index.php?rid=5285361&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ffk14357k464278n4%2F In conclusion, elevation of BNP in patients after TOF repair could reflect volume and pressure load in the RV end-diastolic phase, and ACE-I may reduce BNP levels in a dose-dependent manner. Content Type Journal ArticleCategory Original ArticlePages 1-8DOI 10.1007/s00246-011-0135-1Authors Takuo Furukawa, Department of Pediatrics, Hokkaido University Hospital, Kita 14, Nishi 5, Kita-ku, Sapporo City, Hokkaido 060-8648, JapanTomoaki Murakami, Department of Pediatrics and Adult Congenital Heart Disease, Chiba Cardiovascular Center, Ichihara City, Chiba, JapanMichihiko Ueno, Department of Pediatrics, Hokkaido University Hospital, Kita 14, Nishi 5, Kita-ku, Sapporo City, Hokkaido 060-8648, JapanAtsuhito Takeda, Department of Pediatrics, Hokkaido University Hospital, Kita 14, Nishi 5, Ki... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5285361 Fri, 30 Sep 2011 06:29:05 +0100 5285361 Regionalization in Neonatal Congenital Heart Surgery: The Impact of Distance on Outcome After Discharge http://www.medworm.com/index.php?rid=5285362&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff467nv0k2513uj36%2F Abstract  Studies have shown improved perioperative outcomes after neonatal heart surgery at centers with greater surgical volumes. The impact of increasing distance from such centers on outcome after discharge has not yet been reported. Chart review and cross-sectional survey were performed on children discharged or transferred after undergoing neonatal congenital heart surgery as neonates (<30 days of age) from January 2005 to June 2006. The association of distance from center with mortality and adverse events was analyzed by univariate and multivariate regression and stratified by the Risk Adjustment for Congenital Heart Surgery-1 for complexity. Among 217 patients, those living further from the surgical center were smaller and older at surgery and more likely to... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5285362 Thu, 29 Sep 2011 06:06:38 +0100 5285362 Association Between Left Atrial Size and Measures of Adiposity Among Normal Adolescent Boys http://www.medworm.com/index.php?rid=5273496&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl35h1277t7703m42%2F This study aimed to determine the association between LA size and (1) different components of the metabolic syndrome (body mass index [BMI], waist circumference [WC], insulin levels, lipid levels, and blood pressure), and (2) left ventricular (LV) diameters and diastolic function. Data were collected cross-sectionally from 142 healthy adolescent boys age 16.8 ± 2.0 years in 2009. Measurements of BMI, WC, blood pressure, lipid profile, and insulin were performed. Mode M, two-dimensional Doppler echocardiography was performed. Measurements of LA area, LV end diastolic diameter (EDD), end systolic diameter (ESD), posterior wall, interventricular septum (IVS), and shortening fraction were performed. Tisular Doppler of the diastolic mitral annular E wave (DTE) and A wave ... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5273496 Wed, 28 Sep 2011 05:52:50 +0100 5273496 Right Ventricular Outpouching Associated With a Ventricular Septal Defect: Case Report http://www.medworm.com/index.php?rid=5273497&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F1rvm4r8104487611%2F Content Type Journal ArticleCategory Images in Pediatric CardiologyPages 1-2DOI 10.1007/s00246-011-0059-9Authors Patricia Martínez Olorón, Department of Pediatric Cardiology, Virgen del Camino Hospital, Pamploma, SpainCarlos Romero Ibarra, Department of Pediatric Cardiology, Virgen del Camino Hospital, Pamploma, SpainJose Miguel Galdeano Miranda, Department of Pediatric Cardiology, Cruces Hospital, Pamploma, Spain Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: Pediatric Cardiology) Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5273497 Tue, 27 Sep 2011 05:48:19 +0100 5273497 Predictors of Chronic Valvular Disease in Patients With Rheumatic Carditis http://www.medworm.com/index.php?rid=5260410&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg528377113r071q7%2F This study investigated the predictors of chronic valvular disease in children with rheumatic carditis. The short- to mid-term follow-up records of 88 patients (mean age, 10.68 ± 2.5 years) with chronic rheumatic heart disease were reviewed. The mean follow-up period was 2.95 ± 1.4 years. Valvular involvement completely improved for 24 of the patients (27%) during the follow-up period. The multivariate logistic regression analysis found initial left ventricular dilation to be a significant independent risk factor associated with the persistence of either valvular involvement or mitral regurgitation. Furthermore, persistence of mitral regurgitation was found to be strongly correlated with cardiac murmur at admission. No significant correlation was detec... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5260410 Sat, 24 Sep 2011 05:43:59 +0100 5260410 Critical Ebstein Anomaly in a Fetus Successfully Managed by Elective Preterm Delivery and Surgical Intervention Without Delay After Birth http://www.medworm.com/index.php?rid=5260411&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F02620646t6g7838t%2F This report describes a case of Ebstein anomaly in a fetus with cardiomegaly, severe tricuspid regurgitation, pulmonary regurgitation, and retrograde ductal flow that showed a marked increase in the size of the right atrium with advancing gestational age. Elective preterm delivery was performed at 35 weeks gestation. The prostaglandin E1 infusion resulted in more pronounced systemic hypotension and acidosis secondary to circular shunt across the patent ductus arteriosus as well as pulmonary regurgitation and tricuspid regurgitation. Emergency surgical intervention consisting of main pulmonary artery ligation, ductus arteriosus ligation, central shunt creation, and plication of the right atrium without cardiopulmonary bypass was performed 4 h after birth. At the age of 16 days, the St... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5260411 Sat, 24 Sep 2011 05:43:58 +0100 5260411 Fontan Operation, Vasopressin and Septic Shock: A Case Report on the Usual Treatment in a Peculiar Setting http://www.medworm.com/index.php?rid=5260413&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F771033815t27128p%2F Content Type Journal ArticleCategory Letter to the EditorPages 1-2DOI 10.1007/s00246-011-0104-8Authors Vincenzo Vitale, Department of Pediatric Cardiology and Cardiac Surgery, Intensive Care Unit, Bambino Gesù Children’s Hospital, Piazza S. Onofrio 4, 00165 Rome, ItalyZaccaria Ricci, Department of Pediatric Cardiology and Cardiac Surgery, Intensive Care Unit, Bambino Gesù Children’s Hospital, Piazza S. Onofrio 4, 00165 Rome, ItalyIsabella Favia, Department of Pediatric Cardiology and Cardiac Surgery, Intensive Care Unit, Bambino Gesù Children’s Hospital, Piazza S. Onofrio 4, 00165 Rome, ItalyTiziana Fragasso, Department of Pediatric Cardiology and Cardiac Surgery, Intensive Care Unit, Bambino Gesù Children’s Hospital, Piazza S. Onofrio 4, 00165 Rome, ItalyPaola Cogo, Depart... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5260413 Thu, 22 Sep 2011 06:37:34 +0100 5260413 Absence of the Right Pulmonary Artery Associated With a Partial Anomalous Pulmonary Venous Connection http://www.medworm.com/index.php?rid=5260412&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ff8568175l1406468%2F This report describes the case of a missing right pulmonary artery associated with anomalous left pulmonary venous connection not previously described in the medical literature. Content Type Journal ArticleCategory Case ReportPages 1-3DOI 10.1007/s00246-011-0110-xAuthors Köksal Binnetoğlu, Department of Pediatric Cardiology, Kocaeli University, Faculty of Medicine, Kocaeli, TurkeyCanan Ayabakan, Department of Pediatric Cardiology, Baskent University, Istanbul Research and Teaching Hospital, Oymaci Sokak No: 7, Altunizade/Istanbul, TurkeyÖzlem Sarisoy, Department of Pediatric Cardiology, Baskent University, Istanbul Research and Teaching Hospital, Oymaci Sokak No: 7, Altunizade/Istanbul, TurkeyKürşad Tokel, Department of Pediatric Cardiology, Baskent University, Istanbul Resear... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5260412 Thu, 22 Sep 2011 06:37:34 +0100 5260412 Vertically Oriented Intramural Right Coronary Artery in Complete Transposition of the Great Arteries: Prospective Recognition and Surgical Implications http://www.medworm.com/index.php?rid=5236998&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fa52k58516752j604%2F This report describes a rare case of complete transposition of the great arteries (TGA) with an intramural right coronary artery arising well above the sinotubular junction. Additionally in this case, the left circumflex artery arose anomalously as a branch from the right coronary. Identification of this anatomic anomaly was made by transthoracic echocardiography before surgery. The patient underwent a successful arterial switch operation on day 6 of life. Due to the preoperative diagnosis of the unusual right intramural coronary artery, the coronary transfer technique during the arterial switch was altered, allowing preservation of the right coronary artery. Content Type Journal ArticleCategory Case ReportPages 1-4DOI 10.1007/s00246-011-0108-4Authors Jennifer A. Johnson, Divis... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5236998 Sat, 17 Sep 2011 17:07:00 +0100 5236998 John Locke, “Rhickets” and the Cardiopulmonary Circulation http://www.medworm.com/index.php?rid=5236997&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj63m231805542377%2F Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00246-011-0100-zAuthors A. N. Williams, Virtual Academic Unit, CDC, Northampton General Hospital, Northampton, UK Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: Pediatric Cardiology) Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5236997 Sat, 17 Sep 2011 17:07:00 +0100 5236997 Incidence and Risk Factors for Venous Thromboembolism in Critically Ill Children With Cardiac Disease http://www.medworm.com/index.php?rid=5236999&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F56022525m5068288%2F In this study, we investigated the incidence and risk factors of VTE in critically ill children with cardiac disease, who were prospectively followed-up for VTE after admission to a tertiary care pediatric intensive care unit (PICU). Risk factors were compared between VTE cases and (1) patients in the cohort who did not develop VTE and (2) the next three cardiac patients sequentially admitted to the PICU (case control). Forty-one cases of VTE were identified from 1070 admissions (3.8%). Thirty-seven percent of VTE cases were central venous catheter (CVC)–associated, and 56% of cases were intracardiac. Sixty-six percent of patients were receiving anticoagulation at the time of VTE diagnosis. Increased VTE incidence was associated with unscheduled PICU admission, age <6 month... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5236999 Sat, 17 Sep 2011 05:45:07 +0100 5236999 Differences in Healthy Lifestyles Between Prehypertensive and Normotensive Children and Adolescents in Northern China http://www.medworm.com/index.php?rid=5225174&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft73428004n752726%2F Conclusion  Among children and adolescents, poor prehypertensive status was associated with a low likelihood of healthy lifestyles. Evaluation of multiple healthy lifestyles as a whole should receive more attention for better prevention and control of high blood pressure. Content Type Journal ArticleCategory Original ArticlePages 1-7DOI 10.1007/s00246-011-0112-8Authors Xiaofan Guo, Department of Cardiology, The First Affiliated Hospital of China Medical University, 155 Nanjing North Street, Heping District, Shenyang 110001, People’s Republic of ChinaXingang Zhang, Department of Cardiology, The First Affiliated Hospital of China Medical University, 155 Nanjing North Street, Heping District, Shenyang 110001, People’s Republic of ChinaYang Li, Department of Cardiolog... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5225174 Wed, 14 Sep 2011 05:52:47 +0100 5225174 Vitamin D Deficiency and Arterial Wall Stiffness in Children With Chronic Kidney Disease http://www.medworm.com/index.php?rid=5225175&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg1562x7209761506%2F This study explored the relationship between various parameters of calcium–phosphorus metabolism including 25-hydroxy vitamin D and arterial wall stiffness in pediatric patients with CKD. This study investigated a cohort of 43 children with CKD who had no history of underlying congenital or structural cardiac disease. The Augmentation Index (AI), a measure of peripheral arterial reflective properties using radial artery tonometry, was used as an indirect measure of central aortic stiffness. Serum biochemical markers of calcium–phosphorus metabolism were simultaneously measured. Univariate testing showed that AI correlated with worsening kidney function. Serum 25-hydroxy vitamin D levels were low and correlated negatively with AI (r = −0.39; p < 0.05). Mul... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5225175 Tue, 13 Sep 2011 05:49:32 +0100 5225175 Chronic Constrictive Pericarditis: Unique Cause of Heart Failure in a Child With Tetralogy of Fallot http://www.medworm.com/index.php?rid=5225176&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F42r27000470m4383%2F This report presents a case of tetralogy of Fallot who presented with heart failure at young age of 18 months. This is the first description of coexisting tubercular chronic constrictive pericarditis and tetralogy of Fallot. This case is reported for its unique association of two relatively uncommon clinical entities. The logistic dictum of Hickam in similar circumstances is discussed. Content Type Journal ArticleCategory Case ReportPages 1-3DOI 10.1007/s00246-011-0095-5Authors Saurabh Kumar Gupta, Department of Cardiology, All India Institute of Medical Sciences, Room 29, 7th Floor, New Delhi, 110029 IndiaAnita Saxena, Department of Cardiology, All India Institute of Medical Sciences, Room 29, 7th Floor, New Delhi, 110029 IndiaSachin Talwar, Department of Cardiothoracic and Vasc... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5225176 Mon, 12 Sep 2011 15:50:48 +0100 5225176 Early Outcomes and Prognostic Factors for Left Atrioventricular Valve Reoperation After Primary Atrioventricular Septal Defect Repair http://www.medworm.com/index.php?rid=5225177&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp308p8n6410j029w%2F This study aimed to identify early outcomes of and prognostic factors for left atrioventricular valve (LAVV) reoperation after primary atrioventricular septal defect (AVSD) repair. A retrospective cohort study was performed using the Pediatric Cardiac Care Consortium database, which included 370 patients with previously repaired AVSDs who subsequently underwent LAVV reoperation between 1982 and 2007. Of these patients, 243 underwent LAVV repair, and 127 underwent LAVV replacement. Median time to first reoperation after primary repair was 0.67 years in the repair subgroup and 0.18 years in the replacement subgroup. Thirty-day survival was significantly poorer in the replacement subgroup compared with the repair subgroup (P = 0.0002). In multivariable analysis, indep... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5225177 Sat, 10 Sep 2011 15:41:33 +0100 5225177 Noncompaction Cardiomyopathy in Children With Congenital Heart Disease: Evaluation Using Cardiovascular Magnetic Resonance Imaging http://www.medworm.com/index.php?rid=5225178&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe81v47535m665117%2F This study aimed to assess the impact of NCM on the cardiovascular physiology of children with coexisting CHDs evaluated by cardiovascular magnetic resonance imaging. A case-control study was performed with 12 children (6 patients with combined NCM and CHD and 6 control subjects with isolated CHD). The mean left ventricular end-diastolic and end-systolic volume indices were significantly higher in the CHD patients presenting with NCM than in the CHD patients with no NCM (P = 0.028). However, no differences were observed for right ventricular end-diastolic and end-systolic volume indices, biventricular ejection fractions, stroke volumes and indices, left ventricular wall thickness, left ventricular fractional shortening, cardiac output, or cardiac index. This study suggests t... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5225178 Sat, 10 Sep 2011 15:41:29 +0100 5225178 Recurrent Congestive Heart Failure in a Child Due to Probable Myocarditis http://www.medworm.com/index.php?rid=5225180&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F5kn3145587559r2j%2F This report describes the case of an 8-year-old girl who had three clinically identical episodes of CHF, beginning at the age of 5 years, with each episode preceded by a viral prodrome. The clinical features and the echocardiography and electrocardiogram findings were most supportive of myocarditis. Symptoms and investigations completely normalized between episodes. The third episode, associated with influenza A (strain H1N1) infection, led to cardiac arrest and death on day 2 after admission. Autopsy showed mild cardiomegaly with microscopic foci of myocardial fibrosis and extensive contraction band necrosis. This report is the first to describe recurrent CHF due to probable myocarditis in a pediatric patient. Content Type Journal ArticleCategory Case ReportPages 1-6DO... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5225180 Sat, 10 Sep 2011 15:41:28 +0100 5225180 Intermediate-Term Effects of Intracardiac Communications Created Noninvasively by Therapeutic Ultrasound (Histotripsy) in a Porcine Model http://www.medworm.com/index.php?rid=5225179&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm2283x1776267gmq%2F Abstract  The authors have demonstrated that histotripsy (pulsed cavitational ultrasound) can create atrial septal defects and ventricular septal defects (VSDs) in an open-chest canine model transcutaneously through the intact chest of neonatal pigs. To assess the potential untoward effects of these applications, the clinical, systemic, and pathologic effects of histotripsy-induced intracardiac communications were analyzed. Six neonatal pigs received noninvasive ultrasound therapy to their ventricular septa, then were allowed to survive 1 month for evaluation of intermediate-term effects. The results were compared with those of six previous animals killed immediately and three others killed 2–3 days after the procedure. Brain magnetic resonance imaging (MRI) and... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5225179 Sat, 10 Sep 2011 15:41:28 +0100 5225179 Challenges in Echocardiographic Assessment of Mitral Regurgitation in Children After Repair of Atrioventricular Septal Defect http://www.medworm.com/index.php?rid=5225182&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp64x3x06j266k113%2F In conclusion, echocardiographic assessment of MR severity after AVSD remains challenging. Among the quantitative methods used in this trial, i-VCW and i-VCA performed the best but offered little advantage compared with qualitative MR grade. The utility of regurgitant volume and fraction was severely limited by poor interobserver agreement and frequently negative values. Content Type Journal ArticleCategory Original ArticlePages 1-10DOI 10.1007/s00246-011-0107-5Authors Ashwin Prakash, Department of Cardiology, Children’s Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USARonald V. Lacro, Department of Cardiology, Children’s Hospital Boston, 300 Longwood Avenue, Boston, MA 02115, USALynn A. Sleeper, New England Research Institutes, Watertown, MA, USAL. LuAnn Minich, Uni... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5225182 Sat, 10 Sep 2011 06:02:16 +0100 5225182 Dexmedetomidine: Applications for the Pediatric Patient With Congenital Heart Disease http://www.medworm.com/index.php?rid=5225181&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy567434x88716n55%2F This study aimed to provide a general description of the cardiovascular and hemodynamic effects of dexmedetomidine and an evidence-based review of the literature regarding its use in infants and children with congenital heart disease (CHD). A computerized bibliographic search of the literature on dexmedetomidine use in infants and children with CHD was performed. The cardiovascular effects of dexmedetomidine have been well studied in animal and adult human models. Adverse cardiovascular effects include occasional episodes of bradycardia, with rare reports of sinus pause or cardiac arrest. Both hypotension and hypertension also have been reported. The latter is related to peripheral α2B agonism leading to vasoconstriction. No adverse effects on the pulmonary vasculature have been note... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5225181 Sat, 10 Sep 2011 06:02:16 +0100 5225181 Chiari’s Network as a Cause of Fetal and Neonatal Pathology http://www.medworm.com/index.php?rid=5225183&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe7747m0760l242u0%2F This report describes a case with the novel finding of prenatal compromise due to redundant Chiari’s network and an uncommon case with significant postnatal symptoms. In both cases, the symptoms (fetal hydrops and postnatal cyanosis) resolved spontaneously. The variety of cardiovascular pathologies described in the literature is believed to be associated with persistence of a Chiari network. Knowledge about this not always harmless structure is important for perinatologists, pediatricians, and pediatric cardiologists alike. The clinical importance of this rare pathology is that prenatal counseling may anticipate a generally positive outcome and that surgical intervention generally should be avoided. Content Type Journal ArticleCategory Case ReportPages 1-4DOI 10.1007/s00246-01... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5225183 Sat, 10 Sep 2011 06:02:14 +0100 5225183 Assessment of Coronary Flow Reserve in the Coronary Sinus by Cine 3T-Magnetic Resonance Imaging in Young Adults after Surgery for Tetralogy of Fallot http://www.medworm.com/index.php?rid=5208319&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F258427v4vj84706g%2F This study aimed to evaluate CFR by assessing blood flow in the coronary sinus and systemic endothelial function measured by FMD of the brachial artery in an open prospective study of 10 control subjects and 10 patients (ages, 15–25 years) who have undergone surgical TOF repair. Reduced ventricular function, impaired exercise capacity, and ventricular arrhythmia have been proposed as risk factors for sudden cardiac death after surgical repair of TOF. Some of this may be related to impaired myocardial perfusion. A 3.0T GE Signa Excite scanner was used to achieve phase-contrast, velocity-encoding cine magnetic resonance imaging in the coronary sinus before and during infusion with adenosine (0.14 mg/kg/min). FMD was measured in the brachial artery before arterial occlusion ... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5208319 Thu, 08 Sep 2011 06:06:13 +0100 5208319 Independent Risk Factors for Cardiac Operations in Adults With Congenital Heart Disease: A Retrospective Study of 543 Operations for 500 Patients http://www.medworm.com/index.php?rid=5208318&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fahhv813504236w02%2F This study aimed to identify clinical, morphologic, and hemodynamic risk factors for an adverse outcome. This study retrospectively analyzed a cohort of 500 patients (ages >16 years) who underwent 543 operations between January 2004 and December 2008 at a single center. The composite end point of an adverse outcome was in-hospital death, a prolonged intensive care exceeding 4 days, or both. The composite end point was reached by 253 of the patients (50.6%). Of the 500 patients, 13 (2.6%) died within 30 days after the operation. After logistic regression analysis, the following eight items remained significant: male gender (P = 0.003; odds ratio [OR] 1.8; 95% confidence interval [CI] 1.2–2.6), cyanosis (P > 0.006; OR 3.7; 95% CI 1.5–9.4), fu... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5208318 Thu, 08 Sep 2011 06:06:13 +0100 5208318 P-Wave Dispersion in Children With Acute Rheumatic Fever http://www.medworm.com/index.php?rid=5208320&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp6lp307uu6u74500%2F In conclusion, the P-wave dispersion was higher in the children with acute rheumatic fever than in the healthy control subjects. Content Type Journal ArticleCategory Original ArticlePages 1-5DOI 10.1007/s00246-011-0096-4Authors Celebi Kocaoglu, Department of Pediatrics, Konya Training and Research Hospital, 42080 Konya, TurkeyAhmet Sert, Department of Pediatric Cardiology, Konya Training and Research Hospital, 42080 Konya, TurkeyEbru Aypar, Department of Pediatric Cardiology, Konya Training and Research Hospital, 42080 Konya, TurkeyBulent Oran, Department of Pediatric Cardiology, Selcuk University Hospital, Konya, TurkeyDursun Odabas, Department of Pediatric Cardiology, Konya Training and Research Hospital, 42080 Konya, TurkeyDerya Arslan, Department of Pediatric Cardiology, Selcuk ... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5208320 Tue, 06 Sep 2011 15:50:45 +0100 5208320 Ascending Aortic Aneurysm http://www.medworm.com/index.php?rid=5208321&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu75u688158170474%2F Abstract  A 14-year-old boy presented with an unusual bulging chest noted to be increasing slowly over the last few years. He had no other complaints. Cardiac echocardiography and cardiac magnetic resonance imaging (MRI) showed aneurysmal dilation of the ascending aorta with moderate aortic valve insufficiency and moderate pericardial effusion. The boy underwent reconstruction of his ascending aorta in the form of a Bentall procedure using a 25-mm Carbomedic valve conduit. Content Type Journal ArticleCategory Images in Pediatric CardiologyPages 1-3DOI 10.1007/s00246-011-0103-9Authors Mohammed S. AlHabdan, Section of Pediatric Cardiology, King Faisal Heart Institute, King Faisal Specialist Hospital and Research Center, P.O. Box 3354, Riyadh, Saudi ArabiaAbdullah A. AlSeh... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5208321 Tue, 06 Sep 2011 05:47:47 +0100 5208321 Left Ventricle Pseudoaneurysm After Aortic Valvuloplasty http://www.medworm.com/index.php?rid=5208322&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh01j02u87227h56v%2F This report describes an infant with acquired left ventricular aneurysm after percutaneous aortic balloon valvuloplasty for critical aortic stenosis. The potential risk factors for myocardial injury during cardiac catheterization and potential complications are discussed. Content Type Journal ArticleCategory Case ReportPages 1-4DOI 10.1007/s00246-011-0102-xAuthors Abdullah AlHuzaimi, Division of Cardiology, Faculty of Medicine, British Columbia Children’s Hospital, University of British Columbia, Room 1F22, 4480 Oak Street, Vancouver, BC V6H 3V4, CanadaMartin Hosking, Division of Cardiology, Faculty of Medicine, British Columbia Children’s Hospital, University of British Columbia, Room 1F22, 4480 Oak Street, Vancouver, BC V6H 3V4, CanadaDerek Human, Division of Cardiology, Fac... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5208322 Mon, 05 Sep 2011 16:16:39 +0100 5208322 Restrictive Physiology is Associated With Poor Outcomes in Children With Hypertrophic Cardiomyopathy http://www.medworm.com/index.php?rid=5208323&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fj0020860rr7v88gu%2F Abstract  Pediatric patients with hypertrophic cardiomyopathy (HCM) and restrictive physiology (RP) with poor outcomes have been identified, but data on their course are limited. Our goal was to delineate the clinical features and course of children with HCM and RP. An institutional review of 119 patients identified between 1985 and 2010 with the diagnosis of HCM was performed. The diagnosis of RP was based on >1 echocardiogram along with at least one of the following: left atrial enlargement without evidence of left ventricle dilation, E/E′ ratio ≥ 10, and E/A ratio ≥ 3. Outcomes analysis was performed using Cox or Poisson regression when appropriate. RP was present in 50 (42%) patients. In patients without RP, 10-year freedom-from-death or abor... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5208323 Sun, 04 Sep 2011 10:55:08 +0100 5208323 Cryo-Balloon Angioplasty for Pulmonary Vein Stenosis in Pediatric Patients http://www.medworm.com/index.php?rid=5208326&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F9l35685762n741l3%2F This study sought to determine the safety and effectiveness of cryo-balloon angioplasty (CbA) for pulmonary vein stenosis (PVS) in pediatric patients. Current therapy options for PVS are less than satisfactory due to recurrent progressive restenosis and neointimal proliferation. Catheterization database, hospital records, imaging studies, and pathologic specimens were reviewed for procedural-related and outcomes data in all patients who underwent pulmonary vein (PV) CbA using the Boston Scientific PolarCath Peripheral Dilation System between August 2006 and June 2009. Thirteen patients (19 PVs; median age 13 months [range 3.5 months to 18.5 years] and weight 7.9 kg [range 3.8 to 47.7]) underwent CbA. Mean PVS diameter after CbA increased from 2.19 (±0.6) to 3.77 ... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5208326 Sun, 04 Sep 2011 10:55:07 +0100 5208326 Near Infrared Spectroscopy Describes Physiologic Payback Associated With Excess Postexercise Oxygen Consumption in Healthy Controls and Children With Complex Congenital Heart Disease http://www.medworm.com/index.php?rid=5208325&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh41t6ku3wvr22m03%2F Abstract  Exercise creates a physiologic burden with recovery from such effort crucial to adaptation. Excess postexercise oxygen consumption (EPOC) refers to the body’s increased metabolic need after work. This investigation was designed to determine the role of near infrared spectroscopy (NIRS) in the description of exercise recovery in healthy controls (NL) and children with congenital heart disease (CHD). Subjects were recruited with exercise testing performed to exhaustion. Exercise time (EXT), heart rate (HR), and oxygen consumption (VO2) were measured. Four-site NIRS (brain, kidney, deltoid, and vastus lateralis) were measured during exercise and into recovery to establish trends. Fifty individuals were recruited for each group (NL = 26 boys and 24 girls; C... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5208325 Sun, 04 Sep 2011 10:55:07 +0100 5208325 Multiple Risk Factors Before Pediatric Cardiac Transplantation Are Associated With Increased Graft Loss http://www.medworm.com/index.php?rid=5208324&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F210322nj36011348%2F Abstract  Identification of heart transplant recipients at highest risk for a poor outcome could lead to improved posttransplantation survival. A chart review of primary heart transplantations from 1993 to 2006 was performed. Analysis was performed to evaluate the risk of graft loss for those with a transplantation age less than 1 year, congenital heart disease (CHD), elevated pulmonary vascular resistance (index > 6), positive panel reactive antibody or crossmatch, liver or renal dysfunction, mechanical ventilation, or mechanical circulatory support (MCS). Primary transplantation was performed for 189 patients. Among these patients, 37% had CHD, 23% had mechanical ventilation, and 6% had renal dysfunction. Overall graft survival was 82% at 1 year and ... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5208324 Sun, 04 Sep 2011 10:55:07 +0100 5208324 Upcoming Events in Pediatric Cardiology http://www.medworm.com/index.php?rid=5208327&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq0368321327035r4%2F Content Type Journal ArticleCategory Upcoming EventsPages 1-1DOI 10.1007/s00246-011-0090-x Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: Pediatric Cardiology) Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5208327 Sun, 04 Sep 2011 10:55:06 +0100 5208327 Prevalence of Obesity Among Patients With Congenital and Acquired Heart Disease http://www.medworm.com/index.php?rid=5196204&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F85m8p0458876ml3p%2F Abstract  Overweight and obesity rates have risen dramatically in the United States, with subsequent detrimental comorbidity risks. The rates for obesity among children with congenital and acquired heart disease have rarely been reported. A retrospective cross-sectional study was conducted to determine the prevalence of overweight and obesity in children with heart disease and to identify subgroups at increased risk. A total of 795 cases were identified from a chart review of patients presenting to an urban center’s Pediatric Cardiology Program between 1 January and 31 December 2006. A body mass index (BMI) at the 85th percentile or higher was defined as overweight, and a BMI at the 95th percentile or higher was defined as obese. Subjects with comorbidities affecting body... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5196204 Sat, 03 Sep 2011 06:40:02 +0100 5196204 From Other Journals http://www.medworm.com/index.php?rid=5196205&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F20127lt17379h197%2F Content Type Journal ArticleCategory From Other JournalsPages 1-3DOI 10.1007/s00246-011-0089-3Authors Sanjiv Gandhi, 1507 W. Harrison Street, Chicago, IL 60607, USAOmar M. Khalid, 1507 W. Harrison Street, Chicago, IL 60607, USA Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: Pediatric Cardiology) Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5196205 Thu, 01 Sep 2011 06:12:46 +0100 5196205 Call for a Sudden Cardiac Death Registry: Should Reporting of Sudden Cardiac Death be Mandatory? http://www.medworm.com/index.php?rid=5161392&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe412124255112202%2F Abstract  There is currently no central mandatory pediatric sudden cardiac arrest (SCA) registry in the United States. Perhaps the time is right to actively endorse and develop a pediatric SCD registry, in collaboration with other agencies, advocacy groups, and organizations. This registry, if well constructed, thorough, and validated, would serve not only important SCD epidemiologic purposes but also provide the seed bed for closer collaboration with medical examiners and coroners and enhance critical cascade testing for identification of genotypically and/or phenotypically affected family members. Content Type Journal ArticleCategory Review ArticlePages 1-3DOI 10.1007/s00246-011-0085-7Authors Robert M. Campbell, Department of Pediatrics, Children’s Healthcare of At... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5161392 Mon, 22 Aug 2011 16:00:36 +0100 5161392 Antenatal Calcium Channel Blocker Exposure and Subsequent Patent Ductus Arteriosus in Extremely Low-Birth-Weight Infants http://www.medworm.com/index.php?rid=5161393&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fd48r28t5j2j54167%2F This study aimed to assess whether tocolytic fetal exposure to antenatal calcium channel blockers (aCCB) increases the risk for hemodynamically significant patent ductus arterioses (hsPDA) in extremely low-birth-weight (ELBW) infants. This case-control study investigated ELBW infants (<1,000 g) without cardiac defects in a level 3 neonatal intensive care unit who had survived at least 7 days. Nifedipine was the only aCCB used for this study population. The measurements included the history of aCCB exposure, selected maternal data, hsPDA diagnosis, gestational age at birth, birth weight, mode of delivery, sex, maternal race, location of birth, Apgar scores, and selected neonatal morbidities. The end point of the study was hsPDA, defined as an echocardiographically confirm... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5161393 Mon, 22 Aug 2011 16:00:35 +0100 5161393 Echocardiographic Detection of Coronary Air Embolism as the Cause of Cardiac Arrest in a Neonate With Transposition of the Great Arteries http://www.medworm.com/index.php?rid=5161394&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F71k3515p086x1547%2F Abstract  A hemodynamically stable neonate with transposition of the great arteries suddenly went into cardiac arrest during preparation for transport to the operating room. Emergency echocardiography during cardiac massage detected coronary air embolism as the presumed cause of arrest. After about 15 minutes of resuscitation, it was possible to establish return of spontaneous circulation. Since the most likely source of air was the neonate’s peripheral venous line, we have introduced inline microfilters for all neonates and all patients with right-to-left shunt lesions and did not encounter proven air embolism thereafter. Content Type Journal ArticleCategory Images in Pediatric CardiologyPages 1-2DOI 10.1007/s00246-011-0088-4Authors Michael Weidenbach, Departme... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5161394 Sat, 20 Aug 2011 15:52:22 +0100 5161394 Tetralogy of Fallot With Inverted Great Arteries S, D, I: Case Report, Literature Review, and Discussion of Embryology http://www.medworm.com/index.php?rid=5161395&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb504u70148088532%2F Discussion of Embryology Content Type Journal ArticleCategory Case ReportPages 1-5DOI 10.1007/s00246-011-0071-0Authors Lowell H. Frank, Division of Cardiology, Children’s National Medical Center, 111 Michigan Avenue NW, Washington, DC 20010, USAT. K. Susheel Kumar, Division of Cardiovascular Surgery, University of Michigan, Cardiovascular Center Floor 3 Reception C, 1500 E Medical Center Dr SPC 5864, Ann Arbor, MI 48109, USARichard A. Jonas, Division of Cardiovascular Surgery, Children’s National Medical Center, 111 Michigan Avenue NW, Washington, DC 20010, USAMary T. Donofrio, Division of Cardiology, Children’s National Medical Center, 111 Michigan Avenue NW, Washington, DC 20010, USA Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: Pediatric ... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5161395 Thu, 18 Aug 2011 05:48:18 +0100 5161395 Postoperative Outcome for Hyperglycemic Pediatric Cardiac Surgery Patients http://www.medworm.com/index.php?rid=5161396&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Ft6v1726517g667xk%2F Abstract  This prospective cohort study aimed to determine the morbidity and mortality among hyperglycemic pediatric patients after cardiac surgery. The study was conducted in a pediatric intensive care unit (PICU) for cardiac surgery patients at a university-affiliated, referral, heart hospital. A total of 379 postcardiac surgery pediatric patients participated in the study. No interventions were performed. Measurements of blood glucose level together with other clinical and laboratory data were collected on postoperative days 1, 2, 3, and 7. Mean blood glucose level exceeding 126 mg/dl was considered hyperglycemia, and a level exceeding 200 mg/dl determined severe hyperglycemia. These measurements were analyzed for association with major complications and death. Hyperglyc... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5161396 Thu, 18 Aug 2011 05:48:17 +0100 5161396 Improvement of Cardiac Geometry and Function After Cardiac Resynchronization Therapy for Relapsed Deterioration of Pediatric Dilated Cardiomyopathy Due to a Noncompacted Left Ventricle and Cardiac Dyssynchrony http://www.medworm.com/index.php?rid=5131905&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F5m4524xu51812304%2F We report a pediatric case of successful cardiac resynchronization therapy (CRT) for acute relapsed deterioration of dilated cardiomyopathy with cardiac dyssynchrony due to a noncompacted left ventricle (LV). A 20-month-old female developed severe congestive heart failure, which was classified as New York Heart Association class IV. She failed to thrive despite intravenous inotropic support. Her LV function and dimension improved markedly after CRT. The beneficial effect of CRT in this patient has remained for more than 3 years. Content Type Journal ArticlePages 1-4DOI 10.1007/s00246-011-0086-6Authors Tomoyasu Sasaki, Department of Cardiovascular Surgery, Osaka Medical College Hospital, Daigakutyou 2-7, Takatsuki, Osaka, JapanShintaro Nemoto, Department of Cardiovascular Su... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5131905 Sat, 13 Aug 2011 06:12:55 +0100 5131905 Mitral Regurgitation due to Chordae Tendineae Rupture in an Infant with Aortic Coarctation http://www.medworm.com/index.php?rid=5131906&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl41064481vt14463%2F Abstract  A 2-month-old male suddenly developed mitral regurgitation aggravation while waiting for surgical repair of aortic coarctation. There were no signs of infection or history of trauma. Emergency surgery was performed, during which rupture of chordae tendineae of the A2 portion of the anterior mitral leaflet was confirmed. At last follow-up, 11 months postsurgery, the patient was in an acceptable state, with continuing moderate mitral valve regurgitation. This case demonstrates an unusual but dangerous natural course of aortic coarctation and suggests an additional basis of urgent repair of aortic coarctation. Content Type Journal ArticlePages 1-3DOI 10.1007/s00246-011-0087-5Authors Myung-Mi Kim, Division of Pediatric Cardiology, College of Medicine, Univer... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5131906 Sat, 13 Aug 2011 06:12:54 +0100 5131906 Improving Outcomes from Out-of-Hospital Cardiac Arrest in Young Children and Adolescents http://www.medworm.com/index.php?rid=5131907&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu5h27326hh8655j5%2F This article will review the epidemiology of OHCA, the 2010 CPR guidelines, and developments in public access defibrillation for children. Content Type Journal ArticlePages 1-10DOI 10.1007/s00246-011-0084-8Authors Dianne L. Atkins, Carver College of Medicine, University of Iowa Children’s Hospital, Iowa City, IA 52242, USAStuart Berger, Children’s Hospital of Wisconsin, Medical College of Wisconsin, Milwaukee, WI 53226, USA Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: Pediatric Cardiology) Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5131907 Sat, 13 Aug 2011 06:12:53 +0100 5131907 Acute Myocardial Infarction in a Teenager Due to Adderall XR http://www.medworm.com/index.php?rid=5131908&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk1m702274gu47406%2F We present a case of a 15-year-old male who suffered a myocardial infarction after starting Adderall XR. Patient was otherwise in good health with no previous cardiac abnormalities. Cardiac catheterization was normal, and etiology was presumed to be secondary to acute vasospasm. The patient improved with cessation of medication. Physicians need to carefully screen patients for cardiac abnormalities prior to starting amphetamine-based medications. Content Type Journal ArticlePages 1-3DOI 10.1007/s00246-011-0083-9Authors Angela L. Sylvester, Department of Family Practice, Hinsdale Hospital, Hinsdale, IL, USABrojendra Agarwala, Pediatric Cardiology Comer Children’s Hospital, University of Chicago, Chicago, IL 60637-1470, USA Journal Pediatric CardiologyOnline ISSN 1432-197... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5131908 Sat, 13 Aug 2011 06:12:52 +0100 5131908 Left Main Coronary Artery Atresia: The Role of Computed Tomographic Coronary Angiography http://www.medworm.com/index.php?rid=5126176&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fdlr20614935pw17p%2F Content Type Journal ArticlePages 1-2DOI 10.1007/s00246-011-0081-yAuthors B. Srinivas, Nizam’s Institute of Medical Sciences, Hyderabad, IndiaS. P. Suryawanshi, Nizam’s Institute of Medical Sciences, Hyderabad, IndiaRao D. Seshagiri, Nizam’s Institute of Medical Sciences, Hyderabad, India Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: Pediatric Cardiology) Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5126176 Mon, 08 Aug 2011 19:55:09 +0100 5126176 A Case of Cor Triatriatum With an Abnormal P Wave: The Pacemaker Action From the Specialized Tissue in the Abnormal Septum http://www.medworm.com/index.php?rid=5119821&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fgj44622246512x07%2F Abstract  A boy presented with an abnormal P wave shown on an electrocardiogram (ECG) checkup at school. An echocardiogram and contrast-enhanced computed tomography (CT) showed cor triatriatum with a slit-like opening between the accessory chamber and the left atrium located along the interatrial septum. The boy underwent open heart surgery for excision of the anomalous membrane, and a postoperative ECG showed normal P waves. The excised tissue was examined immnunohistopathologically using antihyperpolarization-activated cyclic nucleotide-gated potassium channel 4 (HCN4) antibody and other staining. The authors confirmed the existence of cells positive to HCN4, indicating that they were sinoatrial node cells or at least cells with electrical automaticity. Content Type J... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5119821 Sun, 07 Aug 2011 05:48:40 +0100 5119821 Cardiac-Related Varicella Mortality in Childhood: A Literature Review With Clinical Experience http://www.medworm.com/index.php?rid=5119822&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F043v435k286484p5%2F Abstract  Among unvaccinated populations, primary varicella zoster virus (VZV) infection results in a minor childhood illness for the majority of individuals. Mortality is rare, and fatalities associated with cardiac complications are exceptional. In a population where routine VZV vaccination is not practised, we report a death in a previously healthy child secondary to VZV myocarditis. A literature review of cardiac-related VZV mortality in childhood is included. This identified a further 13 cases where death was associated with or attributable to, direct involvement of the myocardium or conducting system with what is frequently considered a benign childhood illness. Content Type Journal ArticlePages 1-3DOI 10.1007/s00246-011-0076-8Authors Michael J. O’Grady, Acade... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5119822 Sun, 07 Aug 2011 05:48:39 +0100 5119822 Partial Anomalous Pulmonary Venous Return: Transcatheter Repair http://www.medworm.com/index.php?rid=5109196&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx38854q263233444%2F This report describes a case of partial anomalous pulmonary venous return in a young white girl for whom transcatheter intervention successfully replaced surgical correction. This intervention was feasible because the left lung had dual pulmonary venous drainage. Content Type Journal ArticlePages 1-3DOI 10.1007/s00246-011-0075-9Authors George Kasarala, Division of Cardiology, Department of Pediatrics, Cardinal Glennon Children’s Medical Center, Saint Louis University School of Medicine, 1465 S. Grand Boulevard, St. Louis, MO 63104, USAAndrew Fiore, Department of Surgery, Cardiothoracic, Saint Louis University School of Medicine, 1465 S. Grand Boulevard, St. Louis, MO 63104, USAKenneth Schowengerdt, Division of Cardiology, Department of Pediatrics, Cardinal Glennon Children’s M... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5109196 Sat, 06 Aug 2011 05:47:18 +0100 5109196 Occlusion of Pulmonary Arteriovenous Malformations Using the Amplatzer Vascular Plug/Duct Occluder for a Family With Hereditary Hemorrhagic Telangiectasia http://www.medworm.com/index.php?rid=5109197&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn4q2656402h07812%2F Content Type Journal ArticlePages 1-2DOI 10.1007/s00246-011-0073-yAuthors Min Jung Cho, Department of Pediatrics, Pusan National University Hospital, Ami-dong, Seo-gu, Busan, 602-739 Republic of KoreaJi Ae Park, Department of Pediatrics, Pusan National University Children’s Hospital, Beomeu-li, Mulgum-eup, Yangsan, Keungsangnam-do, 626-770 Republic of KoreaHyoung Doo Lee, Department of Pediatrics, Pusan National University Children’s Hospital, Beomeu-li, Mulgum-eup, Yangsan, Keungsangnam-do, 626-770 Republic of Korea Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: Pediatric Cardiology) Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5109197 Sat, 06 Aug 2011 05:47:17 +0100 5109197 Clinical Significance of Thrombosis in an Intracardiac Blind Pouch After a Fontan Operation http://www.medworm.com/index.php?rid=5109198&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fjv71tm6274412711%2F Abstract  The univentricular heart after the Fontan operation may have a blind pouch formed by the pulmonary stump or rudimentary ventricle according to the anatomy before surgery. Thrombosis in an intracardiac blind pouch of patients with a univentricular heart is a hazardous complication. Because only a few reports have described this complication, the authors evaluated the clinical significance of thrombosis in an intracardiac blind pouch of a univentricular heart. They performed a retrospective review of medical records from August 1986 to December 2007. Four patients were confirmed as having thrombosis in a pulmonary artery stump and one patient as having thrombosis in a rudimentary ventricle shown by cardiac computed tomography (CT). This represents 1.85% (5/271) of p... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5109198 Fri, 05 Aug 2011 05:54:00 +0100 5109198 Intrapericardial and Retrocardial Implantation of Implantable Cardioverter-Defibrillator Lead in a Child with Type 3 Long QT Syndrome http://www.medworm.com/index.php?rid=5109199&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh4581861t2x44178%2F Abstract  A 6-year-old girl with type 3 long QT syndrome was safely and successfully implanted with an implantable cardioverter-defibrillator (ICD) system. Prior to implantation, she had experienced uncontrollable life-threatening arrhythmia in spite of high-dose administration of mexiletine. An ICD coil lead for transvenous use was placed in the intrapericardial and retrocardial space and was connected to a generator placed in front of the posterior sheath of the right abdominal rectal muscle. Administration of a beta-blocker in addition to atrial pacing almost completely eliminated the patient’s life-threatening arrhythmia attacks. Intrapericardial and retrocardial implantation of ICD coil leads might be useful for children. Content Type Journal ArticlePages 1-5DOI ... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5109199 Fri, 05 Aug 2011 05:53:58 +0100 5109199 Echocardiographic Detection of Early Myocardial Calcification in Acute Neonatal Myocarditis Due to Coxsackie Virus Type B http://www.medworm.com/index.php?rid=5109200&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fh776822r78456053%2F Content Type Journal ArticlePages 1-2DOI 10.1007/s00246-011-0080-zAuthors Alessandra Benettoni, Institute for Maternal and Child Health—IRCCS Burlo Garofolo, Trieste, ItalyEmanuela Berton, Institute for Maternal and Child Health—IRCCS Burlo Garofolo, Trieste, Italy Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: Pediatric Cardiology) Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5109200 Thu, 04 Aug 2011 15:41:36 +0100 5109200 Novel Electrocardiogram Manifestations of a Tension Pneumothorax http://www.medworm.com/index.php?rid=5103796&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F8x7j52720010r250%2F Content Type Journal ArticlePages 1-2DOI 10.1007/s00246-011-0067-9Authors Rajesh Punn, Division of Pediatric Cardiology, Stanford University, Lucile Packard Children’s Hospital, 750 Welch Road, Suite # 305, Palo Alto, CA 94304, USAStephen P. Seslar, Division of Cardiology, Electrophysiology, and Pacing, Seattle Children’s Hospital and Regional Medical Center, University of Washington, Washington, USA Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: Pediatric Cardiology) Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5103796 Tue, 02 Aug 2011 15:53:19 +0100 5103796 Radiation Exposure in Children During the Current Era of Pediatric Cardiac Intervention http://www.medworm.com/index.php?rid=5103797&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fp87nm329115puv01%2F This study aimed to evaluate factors that influence variability of X-ray exposure in children with congenital heart diseases during cardiac catheterization. The study included 107 children who underwent either diagnostic (n = 46) or interventional (n = 61) procedures. A custom-made sheet for patient and procedural characteristics was designed. Data were collected, and different correlations were applied to determine factors that influence variability of X-ray exposure. The flouroscopy time (FT) differed significantly between the diagnostic (8.9 ± 6.3 min) and intervention (12.8 ± 9.98 min) groups (P = 0.032). The mean dose–area product (DAP) differed significantly between the two groups (3.775 ± 2.5 Gy/cm2 ... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5103797 Tue, 02 Aug 2011 15:53:16 +0100 5103797 Aortic Exclusion: A Method of Handling Aortic Insufficiency in the Pediatric Population Needing Mechanical Circulatory Support http://www.medworm.com/index.php?rid=5103800&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe56014748471835g%2F We report the first case of aortic exclusion in an infant with moderate to severe aortic insufficiency in need of MCS. Content Type Journal ArticlePages 1-3DOI 10.1007/s00246-011-0069-7Authors Kimberly L. Gandy, Children’s Mercy Hospital, 2401 Gillham Road, Kansas City, MO 64108, USAMichael E. Mitchell, Children’s Mercy Hospital, 2401 Gillham Road, Kansas City, MO 64108, USAAndrew N. Pelech, Children’s Mercy Hospital, 2401 Gillham Road, Kansas City, MO 64108, USARobert A. Niebler, Children’s Mercy Hospital, 2401 Gillham Road, Kansas City, MO 64108, USAGeorge Hoffman, Children’s Mercy Hospital, 2401 Gillham Road, Kansas City, MO 64108, USAStuart Berger, Children’s Mercy Hospital, 2401 Gillham Road, Kansas City, MO 64108, USA Journal Pediatric CardiologyOnline ISSN... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5103800 Tue, 02 Aug 2011 06:12:59 +0100 5103800 Calcified Unruptured Sinus of Valsalva Aneurysm in a Child http://www.medworm.com/index.php?rid=5103799&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn263710h14324484%2F We present the management and outcome of such a case. Content Type Journal ArticlePages 1-3DOI 10.1007/s00246-011-0068-8Authors Arul Dominic Furtado, Department of Cardio-Thoracic Surgery, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bangalore, 560069 IndiaDevananda Nijagal Shivanna, Department of Cardio-Thoracic Surgery, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bangalore, 560069 IndiaSyed Murfad Peer, Department of Cardio-Thoracic Surgery, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bangalore, 560069 IndiaJayaranganath Mahimarangaiah, Department of Pediatric Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bangalore, 560069 India Journal Pediatric CardiologyOnline ISSN 1432-1971Print IS... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5103799 Tue, 02 Aug 2011 06:12:59 +0100 5103799 Isolated Junctional Tachycardia in a Child After Noncardiac Surgery: An Uncommon Clinical Presentation http://www.medworm.com/index.php?rid=5103798&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F7310n72l176862j4%2F This report describes the case of a 3-year-old boy with no cardiac history who experienced transient junctional tachycardia after a right pyeloplasty. Medical therapy was not prescribed initially due to lack of symptoms. However, symptomatic junctional tachycardia recurred, prompting institution of oral beta-blocker therapy. Isolated junctional tachycardia should not be overlooked in the differential diagnosis of pediatric supraventricular tachycardia after noncardiac surgery. Content Type Journal ArticlePages 1-4DOI 10.1007/s00246-011-0072-zAuthors Chenni S. Sriram, Division of Pediatric Cardiology, Department of Pediatric and Adolescent Medicine, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USARoger D. White, Division of Cardio/Thoracic Anesthesia... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5103798 Tue, 02 Aug 2011 06:12:59 +0100 5103798 The Quantitative and Qualitative Responses of Platelets in Pediatric Patients Undergoing Cardiopulmonary Bypass Surgery http://www.medworm.com/index.php?rid=5103801&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F6010m42m678p655m%2F This study provides a new foundation for future studies investigating requirements of platelet supplementation in the setting of pediatric CPB surgery. Content Type Journal ArticlePages 1-5DOI 10.1007/s00246-011-0079-5Authors Vera Ignjatovic, Murdoch Childrens Research Institute, Flemington Road, Parkville, VIC 3052, AustraliaJenny Than, Department of Clinical Haematology, Royal Children’s Hospital, Melbourne, VIC, AustraliaRobyn Summerhayes, Murdoch Childrens Research Institute, Flemington Road, Parkville, VIC 3052, AustraliaFiona Newall, Murdoch Childrens Research Institute, Flemington Road, Parkville, VIC 3052, AustraliaSteve Horton, Department of Cardiac Surgery, Royal Children’s Hospital, Melbourne, VIC, AustraliaAndrew Cochrane, Department of Paediatrics, The University o... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5103801 Tue, 02 Aug 2011 06:12:58 +0100 5103801 Successful Percutaneous Cardiac Resynchronization Despite an Occlusive Thebesian Valve http://www.medworm.com/index.php?rid=5088069&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fb121152716171120%2F We report the case of a patient with symptomatic heart failure referred after an unsuccessful attempt at cardiac resynchronization therapy. An occlusive Thebesian valve prevented entry into the coronary sinus ostium. Careful analysis of the patient’s cardiovascular physiology and anatomy revealed the “fortuitous” presence of a persistent left superior vena cava. Cannulation of this vessel permitted percutaneous retrograde placement of a left ventricular lead into a posterolateral cardiac venous branch resulting in successful cardiac resynchronization. This unique case provides strong evidence that thorough knowledge of cardiac embryology, anatomy, and physiology plays a pivotal role in percutaneous electromechanical intervention for drug-refractory heart failure. Content Ty... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5088069 Sat, 30 Jul 2011 15:52:34 +0100 5088069 Cardiac Lymphangioma in an Infant http://www.medworm.com/index.php?rid=5088071&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk7n4v68786782t4u%2F Content Type Journal ArticlePages 1-3DOI 10.1007/s00246-011-0061-2Authors Hala Almarsafawy, Department of Pediatrics, Mansoura University, Mansoura, EgyptMohamed Matter, Department of Pediatrics, Mansoura University, Mansoura, EgyptMohamed-Adel Elgamal, Department of Congenital and Pediatric Cardiac Surgery, Mansoura University, Mansoura, EgyptKhaled Zalata, Department of Pathology, Mansoura University, Mansoura, Egypt Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: Pediatric Cardiology) Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5088071 Sat, 30 Jul 2011 05:56:24 +0100 5088071 Anomalous Hepatic Vein Draining into the Coronary Sinus http://www.medworm.com/index.php?rid=5088070&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fuj7710402317577v%2F Content Type Journal ArticlePages 1-2DOI 10.1007/s00246-011-0063-0Authors Can Vuran, Department of Cardiovascular Surgery, Baskent University, Istanbul Hospital, Oymaci Sk, No: 7, Altunizade/Istanbul, TurkeyEmre Ozker, Department of Cardiovascular Surgery, Baskent University, Istanbul Hospital, Oymaci Sk, No: 7, Altunizade/Istanbul, TurkeyBurcak Gumus, Department of Radiology, Baskent University, Istanbul Hospital, Oymaci Sk, No: 7, Altunizade/Istanbul, TurkeyRiza Turkoz, Department of Cardiovascular Surgery, Baskent University, Istanbul Hospital, Oymaci Sk, No: 7, Altunizade/Istanbul, Turkey Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: Pediatric Cardiology) Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5088070 Sat, 30 Jul 2011 05:56:24 +0100 5088070 Dilated Tortuous Right Coronary Artery to Coronary Sinus Fistula http://www.medworm.com/index.php?rid=5088072&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu765732362364606%2F Content Type Journal ArticlePages 1-2DOI 10.1007/s00246-011-0055-0Authors Feyza Ayşenur Paç, Department of Pediatric Cardiology, Turkiye Yuksek Ihtisas Education and Research Hospital, Kizilay S, No: 4, Sihhiye, 06100 Ankara, Turkeyİbrahim Ece, Department of Pediatric Cardiology, Turkiye Yuksek Ihtisas Education and Research Hospital, Kizilay S, No: 4, Sihhiye, 06100 Ankara, TurkeyŞevket Ballı, Department of Pediatric Cardiology, Turkiye Yuksek Ihtisas Education and Research Hospital, Kizilay S, No: 4, Sihhiye, 06100 Ankara, Turkey Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: Pediatric Cardiology) Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5088072 Fri, 29 Jul 2011 16:07:55 +0100 5088072 Acute Kidney Injury After Cardiac Surgery in Infants and Children: Evaluation of the Role of Angiotensin-Converting Enzyme Inhibitors http://www.medworm.com/index.php?rid=5088074&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fk70x61536kv885t6%2F This study sought to evaluate the role of angiotensin-converting enzyme (ACE) inhibitors and other nephrotoxic medications in the risk for the development of AKI in neonates and children undergoing cardiac surgery. A retrospective review of all patients younger than 2 years admitted to the cardiac intensive care unit after cardiac surgery from March 2007 to September 2008 was conducted. Patients were included in the review if they received furosemide alone or in combination with an ACE inhibitor. Creatinine clearance was calculated, and the patient’s maximal degree of AKI was classified by pRIFLE. A P value less than 0.05 was considered significant. Of the 319 patients who met the inclusion criteria, 149 (47%) received furosemide therapy alone and 170 (53%) received a combinat... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5088074 Thu, 28 Jul 2011 15:57:11 +0100 5088074 Surgical Management of Congenital Heart Disease: Contribution of the Aristotle Complexity Score to Planning and Budgeting in the German Diagnosis-Related Groups System http://www.medworm.com/index.php?rid=5088073&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu67n165w0770956g%2F This study investigated how this performance evolved during years 2006 to 2010. Hospital costs and reimbursements correlated highly with Aristotle comprehensive complexity levels (Spearman r = 1). Mean costs and reimbursement reached 35,050€ ± 32,665€ and 31,283€ ± 34,732€, respectively, for an underfunding of 10.7%. Basic and comprehensive unit surgical performances were respectively 3036 ± 1009 and 3891 ± 1591 points in 2006. Both performances increased in sigmoid fashion to reach 3883 ± 1344 and 5335 ± 1314 points, respectively, in 2010. Top performances would be achieved in year 2011, and extrapolated costs would comprise about 19,434,094.92€ (95% confidence interval, 11,961,4... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5088073 Thu, 28 Jul 2011 15:57:11 +0100 5088073 Commotio Cordis Presenting as a Temporary Complete Atrioventricular Block in a 2-Year-Old Girl With Congenitally Corrected Transposition of the great Arteries http://www.medworm.com/index.php?rid=5088075&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fbj416379m0763788%2F This report describes a 2-year-old girl with congenitally corrected transposition of the great arteries (ccTGA) who presented with transient complete atrioventricular (AV) block after a mild chest blow. Running around the house with her older sister, she fell to the floor. Her sister also fell and landed on her. The girl became cyanotic and pale and experienced a transient loss of consciousness. At arrival to the emergency department, she had regained consciousness, but she remained pale. An electrocardiogram (ECG) demonstrated complete AV block with a heart rate of 78 beats per minute (bpm). The ECG after admission showed a Wenckebach-type second-degree AV block. Day 2 after admission, a 12-lead ECG showed significant ST and T-wave abnormalities in the precordial leads, but the girl... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5088075 Wed, 27 Jul 2011 18:48:17 +0100 5088075 Serum Levels After Everolimus-Stent Implantation and Paclitaxel-Balloon Angioplasty in an Infant with Recurrent Pulmonary Vein Obstruction After Repaired Total Anomalous Pulmonary Venous Connection http://www.medworm.com/index.php?rid=5088076&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fyl45778557437584%2F Abstract  Everolimus-eluting stents and paclitaxel-coated balloons are used in the interventional treatment of coronary artery disease in adults to reduce the restenosis rate and in small-vessel disease. Both substances are released into the circulation. We report systemic drug exposure after implantation of one everolimus-eluting stent and dilation with one paclitaxel-coated balloon in an 8-month-old infant, which was used as an innovative therapy for recurrent pulmonary vein stenosis. Content Type Journal ArticlePages 1-4DOI 10.1007/s00246-011-0054-1Authors Matthias J. Müller, Department for Pediatric Cardiology and Intensive Care Medicine, Georg-August-University Göttingen, Robert-Koch-Str. 40, 37075 Göttingen, GermanyUlrich Krause, Department for Pediatric Cardio... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5088076 Wed, 27 Jul 2011 15:50:39 +0100 5088076 Formation of Ventricular Aneurysm After Endocarditis in a Child With Methicillin-Resistant Staphylococcus aureus (MRSA) Bacteremia http://www.medworm.com/index.php?rid=5088078&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fhu7176xrt5n57tv5%2F Content Type Journal ArticlePages 1-3DOI 10.1007/s00246-011-0044-3Authors Lasya Gaur, Pediatric Cardiology, Children’s National Medical Center, 111 Michigan Avenue NW, Washington, DC 20010, USAShobhit Madan, Department of Radiology, Children’s Hospital of Pittsburgh of UPMC, 4401 Penn Avenue, Suite Floor 2, Pittsburgh, PA 15224, USAVictor Morell, Division of Pediatric Cardiothoracic Surgery, Children’s Hospital of Pittsburgh of UPMC, 4401 Penn Avenue, Suite Floor 3, Pittsburgh, PA 15224, USAGaurav Arora, Division of Pediatric Cardiology, Children’s Hospital of Pittsburgh of UPMC, 4401 Penn Avenue, Suite Floor 3, Pittsburgh, PA 15224, USA Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: Pediatric Cardiology) Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5088078 Tue, 26 Jul 2011 05:47:08 +0100 5088078 Successful Treatment with Bosentan for Pulmonary Hypertension and Reduced Peripheral Circulation in Juvenile Systemic Sclerosis http://www.medworm.com/index.php?rid=5088077&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fr42t7r67h8120n2t%2F We describe a case of juvenile SSc–PAH successfully treated with bosentan. The present case shows that bosentan ameliorated PAH and peripheral circulation as evaluated by cold stress thermography. No bosentan-related adverse events such as liver dysfunction were observed. Prospective randomized trials are required to validate the effectiveness of bosentan for patients with juvenile SSc; however, bosentan might be useful for the management of patients with juvenile SSc. Content Type Journal ArticlePages 1-3DOI 10.1007/s00246-011-0056-zAuthors Masaki Shimizu, Department of Pediatrics, School of Medicine, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, JapanYoko Hashida, Department of Pediatrics, School of Medicine, Institute of Medical, Ph... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5088077 Tue, 26 Jul 2011 05:47:08 +0100 5088077 Relationship of Pulmonary Artery Wedge Pressure to Left Atrial Pressure and Pulmonary Vascular Resistance in Preoperative Fontan Patients http://www.medworm.com/index.php?rid=5070126&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fm1517626466q4w87%2F This study was to validate PAWp as an accurate estimate of LAp for calculating pulmonary vascular resistance in single-ventricle patients after the bidirectional Glenn operation. A prospective study measuring direct branch pulmonary artery pressures, ipsilateral PAWp, and direct LAp to calculate pulmonary and systemic blood flows was conducted. Pulmonary vascular resistance (PVR) was calculated for each patient using the PAWp and compared to the PVR calculated by direct LAp measurements. Twenty-eight patients were enrolled; 27 were eligible for study inclusion. Ages ranged from 21 to 60 months and weights ranged from 9.5 to 20.8 kg. Underlying congenital heart defect diagnoses varied, with all patients either functionally or anatomically univentricular. Left mPAWp measured ... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5070126 Mon, 25 Jul 2011 15:44:26 +0100 5070126 Prospective, Longitudinal Study of Plastic Bronchitis Cast Pathology and Responsiveness to Tissue Plasminogen Activator http://www.medworm.com/index.php?rid=5063503&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fuv47q3vt661428t8%2F Abstract  Plastic bronchitis (PB) is a rare disease that often occurs in patients with congenital heart disease (CHD) who have undergone staged single-ventricle palliation. It is characterized by the formation of rubbery “casts” in the airways. PB treatment frequently includes inhaled tissue plasminogen activator (tPA). However, the efficacy of tPA to reduce cast burden is unknown. This is further complicated by our lack of knowledge of cast composition. We obtained spontaneously expectorated PB casts from children (n = 4) with CHD and one adult patient with idiopathic PB. Pathological assessment was made from paraffin-preserved samples. Casts were treated with phosphate-buffered saline (PBS) or tPA. Cast response to tPA was assessed by changes in cast weight ... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5063503 Sat, 23 Jul 2011 15:49:04 +0100 5063503 Outcomes of Hypoplastic Left Heart Syndrome in Low-Birth-Weight Patients http://www.medworm.com/index.php?rid=5063504&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fu130608x70487j06%2F The objective of this study was to assess outcomes of hypoplastic left heart syndrome (HLHS) patients weighing ≤2.5 kg throughout staged palliation. We performed a single-center retrospective review. Abstracted data included gestational age, birth weight, presence of noncardiac anomalies, and survival through Fontan. Fifty-two patients met inclusion criteria, with a median birth weight of 2.14 kg and gestational age of 36 weeks. Five patients received comfort care only. Of 47 patients who underwent initial surgical palliation, 51% survived to initial hospital discharge. Birth weight and gestational age (GA) were similar between survivors and nonsurvivors. Compared with survivors, risk factors for death prior to initial hospital discharge were as follows: small for GA... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5063504 Fri, 22 Jul 2011 17:07:11 +0100 5063504 Congenital Subclavian Steal Syndrome Associated With Heterotaxy Syndrome and Atrioventricular Septal Defect http://www.medworm.com/index.php?rid=5063505&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F2100643823p63502%2F Abstract  An infant under follow-up evaluation since the fetal stage was detected to have subclavian steal syndrome (SSS) associated with heterotaxy syndrome and atrioventricular septal defect. Such a complex association has not been reported previously. Congenital SSS occurs as a result of a subclavian artery originating from the main pulmonary artery through the ductus instead of the aortic arch. In rare cases, as in the reported case, it may occur due to proximal segment atresia of the left subclavian artery. Content Type Journal ArticlePages 1-2DOI 10.1007/s00246-011-0048-zAuthors Murat Ciftel, Department of Pediatric Cardiology, Faculty of Medicine, Akdeniz University, Antalya, TurkeyFirat Kardelen, Department of Pediatric Cardiology, Faculty of Medicine, Akdeniz ... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5063505 Thu, 21 Jul 2011 18:10:47 +0100 5063505 Exercise-Induced Intraventricular Obstruction in a Child with Near Syncope and Chest Pain During Exercise http://www.medworm.com/index.php?rid=5063508&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fyr77280q69140863%2F We report the case of a 10-year-old girl with two episodes of light-headedness and chest pain during exercise. She had an unremarkable clinical record, physical examination, ECG, and echocardiogram. Noninvasive ischemia tests were positive, but coronary angiography was normal. Exercise stress echocardiogram revealed an exercise-induced intra-left-ventricular obstruction with a peak gradient of 78 mmHg and replicated her symptoms. After starting beta-blocker therapy her clinical status improved and no residual obstruction was detected. The authors review this unsuspected clinical condition, seldom reported in the adult population and, to our knowledge, never before in a child. Content Type Journal ArticlePages 1-4DOI 10.1007/s00246-011-0052-3Authors Artur Lopes, Cardiology ... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5063508 Thu, 21 Jul 2011 18:10:44 +0100 5063508 Exercise-Induced Myocardial Ischemia in a Case of Anomalous Origin of the Left Main Coronary Artery from the Noncoronary Sinus of Valsalva http://www.medworm.com/index.php?rid=5063507&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F00745757280043h1%2F We report a case of anomalous origin of the left main coronary artery (LCA) from the noncoronary sinus of valsalva (LCANCS) in a young healthy patient who presented with syncope and cardiopulmonary arrest during exercise. The enhanced computed tomography showed acute angle take-off (AAT) of LCA, and the exercise stress thallium-201 myocardial scintigraphy demonstrated a large defect at the LCA perfusion region. We propose that the coexistence of AAT and resulting ischemia causes sudden cardiac death during exercise in the patients with LCANCS. Content Type Journal ArticlePages 1-4DOI 10.1007/s00246-011-0051-4Authors Mitsunori Nishiyama, Graduate School of Medicine, Tokyo Medical and Dental University, Tokyo, JapanShouzaburo Doi, Graduate School of Medicine, Tokyo Medical and Den... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5063507 Thu, 21 Jul 2011 18:10:44 +0100 5063507 Accuracy of Doppler-Derived Estimation of Pulmonary Vascular Resistance in Congenital Heart Disease: An Index of Operability http://www.medworm.com/index.php?rid=5063506&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fg1117h1t4046v071%2F In conclusion, Doppler-derived TRV/VTIm ratio is a reliable index that may be helpful as a supplementary diagnostic tool for the selection of modality of treatment and follow-up of patients with PAH and increased PVR. Content Type Journal ArticlePages 1-7DOI 10.1007/s00246-011-0035-4Authors Gholam Hossein Ajami, Department of Pediatrics, Division of Pediatric Cardiology, Namazi Hospital, Shiraz University of Medical Sciences, 71937-11351 Shiraz, IranSirous Cheriki, Department of Pediatrics, Division of Pediatric Cardiology, Namazi Hospital, Shiraz University of Medical Sciences, 71937-11351 Shiraz, IranHamid Amoozgar, Department of Pediatrics, Division of Pediatric Cardiology, Namazi Hospital, Shiraz University of Medical Sciences, 71937-11351 Shiraz, IranMohammad Borzouee, Departm... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5063506 Thu, 21 Jul 2011 18:10:44 +0100 5063506 Infliximab Treatment for Pediatric Refractory Kawasaki Disease http://www.medworm.com/index.php?rid=5063509&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F802157778k134234%2F Content Type Journal ArticlePages 1-5DOI 10.1007/s00246-011-0045-2Authors Laura L. Blaisdell, Department of Pediatrics, Maine Medical Center, 887 Congress Street Suite 310, Portland, ME 04102, USAJennifer A. Hayman, Barbara Bush Children’s Hospital, Maine Medical Center, 887 Congress Street Suite 310, Portland, ME 04102, USAAdrian M. Moran, Division of Pediatric Cardiology, Department of Pediatrics, Maine Medical Center, 887 Congress Street Suite 310, Portland, ME 04102, USA Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: Pediatric Cardiology) Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5063509 Wed, 20 Jul 2011 12:27:41 +0100 5063509 Coronary Artery-to-Pulmonary Artery Fistula in a Case of Pulmonary Atresia With Ventricular Septal Defect http://www.medworm.com/index.php?rid=5052648&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F48w1jtvg56x6wu23%2F Abstract  Pulmonary atresia with ventricular septal defect (PA-VSD) can be associated with varying pulmonary artery connections. The origin of pulmonary blood flow can vary greatly among patients, and some case reports have described the presence of left coronary artery-to-pulmonary artery fistula. Two cases of patients found to have coronary artery-to-pulmonary artery fistula in the settings of PA-VSD are reported. Content Type Journal ArticlePages 1-6DOI 10.1007/s00246-011-0043-4Authors Shyam K. Sathanandam, The Heart Institute for Children, Advocate Hope Children’s Hospital, 4440 W 95th Street, Oak Lawn, IL 60453, USARohit S. Loomba, Children’s Hospital of Wisconsin, Medical College of Wisconsin Affiliated Hospitals, 9000 Wisconsin Avenue, Wauwatosa, WI 53226, U... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5052648 Mon, 18 Jul 2011 15:53:47 +0100 5052648 Postoperative Mass in the Left Atrium From a Transesophageal Echocardiography: An Omitted Myxoma or Thrombus? http://www.medworm.com/index.php?rid=5039167&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fbh6347726n764164%2F Content Type Journal ArticlePages 1-2DOI 10.1007/s00246-011-0047-0Authors Silin Pan, Children’s Hospital, Qingdao University, Heart Center, Qingdao, ChinaQuansheng Xing, Children’s Hospital, Qingdao University, Heart Center, Qingdao, ChinaShuhua Duan, Children’s Hospital, Qingdao University, Heart Center, Qingdao, China Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: Pediatric Cardiology) Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5039167 Thu, 14 Jul 2011 16:56:28 +0100 5039167 Results From Extrapleural Clipping of a Patent Ductus Arteriosus in Seriously Ill Preterm Infants http://www.medworm.com/index.php?rid=5039168&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F57764n1326646412%2F This study reports the immediate postoperative clinical outcomes for 24 extrapleurally clipped premature infants presenting with congestive heart failure in high-risk comorbidity status between March 2007 and November 2010. The demographics, preoperative clinical characteristics, and postoperative outcomes of the patients, including echocardiographic assessments, were evaluated. No surgery-related mortalities occurred. Four mortalities occurred after surgery due to sepsis and bleeding diathesis. All 20 surviving patients exhibited normal left ventricular dimensions and systolic function in the immediate follow-up period. The study shows that extrapleural clip closure in seriously ill premature infants has an acceptable overall short-term mortality and complication rate with a high ra... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5039168 Thu, 14 Jul 2011 06:03:07 +0100 5039168 Murmur and Doppler Alternans in Critical Pulmonary Stenosis http://www.medworm.com/index.php?rid=5030267&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fq0048055521q85l4%2F This report describes a case of murmur alternans in critical pulmonary stenosis that also showed Doppler alternans on echocardiography. The underlying cause was right ventricular systolic dysfunction. Content Type Journal ArticlePages 1-4DOI 10.1007/s00246-011-0033-6Authors Mehnaz Atiq, Department of Pediatrics and Child Health, Aga Khan University Hospital, P.O. Box 3500, Stadium Road, Karachi, 74800 PakistanSaleem Akhter, Department of Pediatrics and Child Health, Aga Khan University Hospital, P.O. Box 3500, Stadium Road, Karachi, 74800 PakistanSheikh Abdul Sattar, Department of Pediatrics and Child Health, Aga Khan University Hospital, P.O. Box 3500, Stadium Road, Karachi, 74800 PakistanShazia Mohsin, Department of Pediatrics and Child Health, Aga Khan University Hospital, P.O.... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5030267 Tue, 12 Jul 2011 05:57:11 +0100 5030267 Treatment of Acute Heart Failure Using Levosimendan for a Patient With Dilated Cardiomyopathy, Chronic Renal Failure, and Hypertension http://www.medworm.com/index.php?rid=5030268&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl4l8x57506032n84%2F Abstract  The clinical and hemodynamic effects of compassionate therapy with levosimendan were evaluated in a 14-year–old patient with end-stage renal disease and arterial hypertension secondary to glycogenosis type Ia. The patient previously had normal heart function but experienced acute development of severe myocardial dysfunction resistant to diuretic therapy and inotropic support. Levosimendan administration was followed by a marked clinical and echocardiographic improvement. The authors believe that levosimendan may be useful for cases of resistant acute heart failure with arterial hypertension. Although administration of levosimendan is not recommended for patients with chronic renal disease, no adverse effect was observed. Therapeutic action for these patients see... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5030268 Sun, 10 Jul 2011 05:53:05 +0100 5030268 Heart Rate Variability and Exercise Capacity of Patients With Repaired Tetralogy of Fallot http://www.medworm.com/index.php?rid=5020364&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fyr62u33268700257%2F This study investigated the correlation between HRV and exercise capacity in 30 patients with TOF after surgery for total correction. The median age of the patients was 14 years (range, 9–25 years), and the median follow-up period was 11.6 months (range, 5.3–20.2 months). Low- and high-frequency-domain HRV significantly correlated with VO2 peak (r = 0.56, P = 0.001 and r = 0.44, P = 0.02, respectively). After the 1-year follow-up evaluation, VO2 peak and HRV analysis did not differ from those at entry to the study. However, low- and high-frequency-domain HRV still correlated significantly with VO2 peak (r = 0.43, P = 0.03 and r = 0.52, P = 0.007, respectively). Left ventricular early... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5020364 Fri, 08 Jul 2011 06:37:23 +0100 5020364 Management of Warfarin in Children With Heart Disease http://www.medworm.com/index.php?rid=5020365&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F8400971120713225%2F Content Type Journal ArticlePages 1-1DOI 10.1007/s00246-011-0042-5Authors Sophie Jones, Department of Clinical Haematology, Royal Children’s Hospital, Parkville, AustraliaFiona Newall, Department of Clinical Haematology, Royal Children’s Hospital, Parkville, Australia Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: Pediatric Cardiology) Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5020365 Thu, 07 Jul 2011 05:45:38 +0100 5020365 The Contribution of Chromosomal Abnormalities to Congenital Heart Defects: A Population-Based Study http://www.medworm.com/index.php?rid=5009799&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl452046618gt4200%2F In conclusion, in our study, approximately 1 in 8 infants with a CHD had a chromosomal abnormality. Clinicians should have a low threshold at which to obtain testing for chromosomal abnormalities in infants with CHDs, especially those with certain types of CHDs. Use of new technologies that have become recently available (e.g., chromosomal microarray) may increase the identified contribution of chromosomal abnormalities even further. Content Type Journal ArticlePages 1-11DOI 10.1007/s00246-011-0034-5Authors Robert J. Hartman, National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 1600 Clifton Road, MS E-86, Atlanta, GA, USASonja A. Rasmussen, National Center on Birth Defects and Developmental Disabilities, Centers for Disease ... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=5009799 Tue, 05 Jul 2011 05:34:18 +0100 5009799 Outcomes and Risk Factors for Mortality in Premature Neonates With Critical Congenital Heart Disease http://www.medworm.com/index.php?rid=4993633&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fy378u74448464327%2F Abstract  We sought to describe contemporary outcomes and identify risk factors for hospital mortality in premature neonates with critical congenital heart disease who were referred for early intervention. Neonates who were born before 37 weeks’ gestation with critical congenital heart disease and admitted to our institution from 2002 to 2008 were included in this retrospective cohort study. Critical congenital heart disease was defined as a defect requiring surgical or transcatheter cardiac intervention or a defect resulting in death within the first 28 days of life. Logistic regression analyses were performed to identify risk factors for mortality before hospital discharge. The study included 180 premature neonates, of whom 37 (21%) died during their initial h... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=4993633 Tue, 28 Jun 2011 15:49:47 +0100 4993633 Successful Treatment of a Newborn With Genetically Confirmed Long QT Syndrome 3 and Repetitive Torsades De Pointes Tachycardia http://www.medworm.com/index.php?rid=4993634&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F65871355528335qr%2F Content Type Journal ArticlePages 1-2DOI 10.1007/s00246-011-0037-2Authors Christian Paech, Department for Pediatric Cardiology, University of Leipzig––Heart Center, 04289 Leipzig, GermanyPhilipp Suchowerskyj, Department for Pediatric Cardiology, University of Leipzig––Heart Center, 04289 Leipzig, GermanyRoman Anton Gebauer, Department for Pediatric Cardiology, University of Leipzig––Heart Center, 04289 Leipzig, Germany Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: Pediatric Cardiology) Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=4993634 Tue, 28 Jun 2011 15:49:43 +0100 4993634 Benign Outcome of Pulmonary Hypertension in Neonates With a Restrictive Patent Foramen Ovale Versus Result for Neonates With an Unrestrictive Patent Foramen Ovale http://www.medworm.com/index.php?rid=4985714&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F84861657hn0ghg2r%2F Abstract  Premature closure or restriction of foramen ovale (FO) is a rare but known entity. FO diameter <2 mm and Doppler velocity >120 cm/s, diameter <3 mm with Doppler velocity measured gradient >5 mmHg have all being used by various authors to describe this entity. Some neonates with restrictive FO have been noted to have severe pulmonary hypertension with no clinical signs or symptoms and with spontaneous resolution without any intervention. Seven consecutive neonates were indentified in the database between 01/01/2003 and 06/30/2010 with diagnosis of restrictive PFO (diameter <2 mm) with structurally normal heart and their initial and follow-up echocardiogram as well as hospital medical records were reviewed. As a control, seven ... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=4985714 Mon, 27 Jun 2011 17:51:15 +0100 4985714 Tako-Tsubo Syndrome in a 12-Year-Old Girl: Exhausted Heart, Not Broken Heart http://www.medworm.com/index.php?rid=4985715&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fx1135738v4244n31%2F We report the case of a 12-year-old girl with Tako-tsubo cardiomyopathy. She was successfully treated in our Pediatric Intensive Care Unit for acute left ventricular failure, which occurred after a brief submersion in sea water. At 2-month follow-up she showed an almost complete recovery of cardiac function. We consider Tako-tsubo syndrome, which is rarely reported in the pediatric population, to be the most likely diagnosis. Content Type Journal ArticlePages 1-4DOI 10.1007/s00246-011-0038-1Authors Sandro Dessardo, University Hospital Center Rijeka, T. Strizica 3, 51000 Rijeka, CroatiaVjekoslav Tomulić, University Hospital Center Rijeka, T. Strizica 3, 51000 Rijeka, CroatiaNada Sindičić Dessardo, University Hospital Center Rijeka, T. Strizica 3, 51000 Rijeka, Croatia Jo... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=4985715 Mon, 27 Jun 2011 17:51:14 +0100 4985715 Quality of Life Experienced by Adolescents and Young Adults With Congenital Heart Disease http://www.medworm.com/index.php?rid=4985716&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fe035813741r26j20%2F This study aimed to assess the quality of life (QOL) experienced by adolescents and young adults with congenital heart disease (CHD) and to determine which factors negatively affect adjustment and which factors increase resilience. The participants in the study were 74 patients with CHD (41 males and 33 females) ranging in age from 12 to 26 years (mean age, 18.76 ± 3.86 years). Demographic information and a complete clinical history were obtained. The participants were interviewed regarding topics such as social support, family educational style, self-image, and physical limitations. They responded to questions in a standardized psychiatric interview (SADS-L) and completed a self-report questionnaire (WHOQOL-BREF) for assessment of QOL. Compared with the Portugue... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=4985716 Mon, 27 Jun 2011 17:51:12 +0100 4985716 Upcoming Events in Pediatric Cardiology http://www.medworm.com/index.php?rid=4970150&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fv62n401200420373%2F Content Type Journal ArticlePages 1-1DOI 10.1007/s00246-011-0031-8 Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: Pediatric Cardiology) Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=4970150 Tue, 21 Jun 2011 16:41:46 +0100 4970150 From Other Journals http://www.medworm.com/index.php?rid=4970149&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F534n3r7047l71m03%2F Content Type Journal ArticlePages 1-5DOI 10.1007/s00246-011-0030-9Authors Sanjiv Gandhi, 1507 W. Harrison St, Chicago, IL 60607, USAOmar M. Khalid, 1507 W. Harrison St, Chicago, IL 60607, USA Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: Pediatric Cardiology) Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=4970149 Tue, 21 Jun 2011 16:41:46 +0100 4970149 Congenital Aorta Right Atrial Fistula: Successful Transcatheter Closure With the Amplatzer Occluder http://www.medworm.com/index.php?rid=4946478&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F556670t36w117803%2F Content Type Journal ArticlePages 1-3DOI 10.1007/s00246-011-0026-5Authors Sharad Chandra, Department of Cardiology, Chhatarpati Shahuji Maharaj Medical University (CSMMU), King George Medical College (KGMC), Lucknow, IndiaSudarshan Vijay, Department of Cardiology, Chhatarpati Shahuji Maharaj Medical University (CSMMU), King George Medical College (KGMC), Lucknow, IndiaDaljeet Kaur, Department of Cardiology, Chhatarpati Shahuji Maharaj Medical University (CSMMU), King George Medical College (KGMC), Lucknow, IndiaSudhanshu Dwivedi, Department of Cardiology, Chhatarpati Shahuji Maharaj Medical University (CSMMU), King George Medical College (KGMC), Lucknow, India Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: Pediatric Cardiology) Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=4946478 Fri, 17 Jun 2011 12:01:39 +0100 4946478 Influence of Chromosome 22q11.2 Microdeletion on Postoperative Calcium Level After Cardiac-Correction Surgery http://www.medworm.com/index.php?rid=4946479&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F8lr0741638974830%2F This study included 22 children diagnosed with del22q11.2 syndrome and 110 children without del22q11.2 syndrome from Nanjing Children’s Hospital. Clinical examinations and blood ionized calcium testing were reviewed retrospectively. A comparative study of postoperative calcium levels and complications of del22q11.2 patients with nondeletion patients was performed. Association between postoperative hypocalcaemia and adverse incidents after cardiac correction was also examined. Postoperative hypocalcaemia was observed among 86.4% of del22q11.2 patients and among only 47.3% of nondeletion subjects. The difference was statistically significant (P = 0.0017). Patients with del22q11.2 syndrome also had a much sharper decrease in serum calcium levels during the first 6 h aft... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=4946479 Thu, 16 Jun 2011 05:53:07 +0100 4946479 Takayasu’s Arteritis Mimicking Unilateral Pulmonary Artery Agenesis in a Child With Severe Pulmonary Hypertension and Right Heart Failure: A Diagnostic Dilemma http://www.medworm.com/index.php?rid=4946480&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F71u2k622632g260v%2F Abstract  Affliction of the pulmonary arteries in Takayasu’s arteritis is uncommon. Moreover the incidence of pulmonary artery involvement in this condition is often underestimated because of asymptomatic nature in most patients. Severe involvement may however present with pulmonary artery hypertension and hemoptysis, which may prove to be fatal. This case report describes a 9-year-old girl with severe pulmonary hypertension and right heart failure secondary to total occlusion of the right pulmonary artery. Detailed clinical examination and computed tomography (CT) angiography confirmed this diagnosis. Content Type Journal ArticlePages 1-5DOI 10.1007/s00246-011-0025-6Authors Sudeep Kumar, Department of Cardiology, Sanjay Gandhi Postgraduate Institute of Medical Scien... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=4946480 Wed, 15 Jun 2011 06:19:01 +0100 4946480 Significance of Circulating Hepatocyte Growth Factor in Protein-Losing Enteropathy After Fontan Operation http://www.medworm.com/index.php?rid=4936692&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fcmw2217v0431m48g%2F Abstract  The purpose of this study was to measure serum hepatocyte growth factor (HGF) and elucidate the relationship between HGF and protein-losing enteropathy (PLE) after Fontan operation (FO). Ten patients with PLE (mean age 15.7 ± 8.7 years) who underwent FO were enrolled. Control group 1 comprised 20 patients without PLE after FO, and control group 2 comprised 10 patients with nephrotic syndrome (NS). Serum HGF, vascular endothelial growth factor, albumin, and random stool alpha-1 antitrypsin concentration were measured. Transthoracic echocardiography was completed. Serum HGF level was significantly greater in the PLE patients (0.61 ± 0.27 ng/ml) after FO than in the two control groups (0.41 ± 0.12 ng/ml [P = 0.... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=4936692 Sat, 11 Jun 2011 06:04:22 +0100 4936692 A Case of Left Main Pulmonary Artery Aneurysm Associated with Valvular Pulmonary Stenosis in a Child http://www.medworm.com/index.php?rid=4936691&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fl25250883n066261%2F We report here a pediatric case of left pulmonary artery aneurysm associated with valvular pulmonary stenosis and a hypoplastic right pulmonary artery, which we confirmed via multidetector computed tomography angiography. Content Type Journal ArticlePages 1-2DOI 10.1007/s00246-011-0021-xAuthors Ran Lee, Department of Pediatrics, School of Medicine, Konkuk University, Gwangjin-gu, Seoul, KoreaJae Sung Son, Department of Pediatrics, School of Medicine, Konkuk University, Gwangjin-gu, Seoul, KoreaYong Mean Park, Department of Pediatrics, School of Medicine, Konkuk University, Gwangjin-gu, Seoul, Korea Journal Pediatric CardiologyOnline ISSN 1432-1971Print ISSN 0172-0643 (Source: Pediatric Cardiology) Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=4936691 Sat, 11 Jun 2011 06:04:22 +0100 4936691 Oral Budesonide Treatment for Protein-Losing Enteropathy in Fontan-Palliated Patients http://www.medworm.com/index.php?rid=4936693&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2Fn583837412623397%2F Abstract  Protein-losing enteropathy (PLE) is a rare complication of Fontan palliation associated with significant morbidity and mortality. It is characterized by the loss of serum proteins into the intestinal lumen, and its pathophysiology likely involves enteral inflammation. Budesonide, an oral steroid, is an attractive treatment option because of its potent enteral activity and minimal systemic side effects. A single-center, retrospective review of Fontan-palliated PLE patients treated with oral budesonide for 6 months or longer was performed. The patient characteristics reviewed were demographics, anatomic diagnosis, budesonide treatment (dose and duration), other medications and therapeutic interventions, hospitalizations, serum albumin levels, medical complicati... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=4936693 Fri, 10 Jun 2011 06:35:55 +0100 4936693 Unmasking of Neonatal Renovascular Hypertension by Milrinone Used for Cardiac Dysfunction http://www.medworm.com/index.php?rid=4923184&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F20650112729221q7%2F We present this case to alert clinicians to the rarer causes of left-ventricular dysfunction and to point out that its etiology, i.e., hypertension, may not be apparent until there is improvement in the systolic function of the left ventricle. Content Type Journal ArticlePages 1-3DOI 10.1007/s00246-011-0027-4Authors Prema Ramaswamy, Division of Pediatric Cardiology, Maimonides Infants and Children’s Hospital of Brooklyn, Brooklyn, NY, USASusan Schulman, Department of Pediatrics, Maimonides Infants and Children’s Hospital of Brooklyn, Brooklyn, NY, USAPanayot Filipov, Division of Neonatology, Maimonides Infants and Children’s Hospital of Brooklyn, Brooklyn, NY, USAJuan C. Kupferman, Division of Pediatric Nephrology, Maimonides Infants and Children’s Hospital of Brooklyn, Br... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=4923184 Wed, 08 Jun 2011 15:45:29 +0100 4923184 Total Anomalous Pulmonary Venous Drainage Complicated by Tracheoesophageal Fistula http://www.medworm.com/index.php?rid=4923185&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F1482r18044702601%2F Abstract  We provided emergency treatment to a 1-day-old neonate (1600 g) with tracheoesophageal fistula (gross classification, type C) and total anomalous pulmonary venous drainage (infracardiac type) complicated by pulmonary venous obstruction. Emergency surgery was required because the tracheoesophageal fistula would have caused respiratory failure. Here we report the perioperative management techniques we used, including the surgical strategy. Content Type Journal ArticlePages 1-3DOI 10.1007/s00246-011-0011-zAuthors Toru Okamura, Department of Cardiovascular Surgery, School of Medicine, Ehime University, Shitsukawa, Toon city, Ehime 791-0295, JapanMitsugi Nagashima, Department of Cardiovascular Surgery, School of Medicine, Ehime University, Shitsukawa, Toon cit... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=4923185 Wed, 08 Jun 2011 15:45:27 +0100 4923185 Establishment of Secondary Iron Overloaded Mouse Model: Evaluation of Cardiac Function and Analysis According to Iron Concentration http://www.medworm.com/index.php?rid=4923187&cid=s_33303_7_f&fid=33303&url=http%3A%2F%2Fwww.springerlink.com%2Fcontent%2F041440545g0rn213%2F In this study, we established murine model of secondary iron overload, studied the changes in cardiac function with echocardiography, and examined the histopathologic changes. Three experimental groups of the six week-old C57/BL mice (H-2b) were injected intraperitoneally with 10 mg of iron dextran daily 5 days a week for 2, 4, and 6 weeks. Cumulative doses of iron for the three experimental groups were 100, 200, and 300 mg, while the control groups were injected with the same amounts of phosphate-buffered saline. We studied the cardiac function under anesthesia with echocardiography using a GE Vivid7 Dimension system. Plasma iron levels and liver iron contents were measured. The hearts and livers were harvested and stained with H&E and Perls Prussian blue for iro... Pediatric Cardiology journals http://www.medworm.com/rss/comments.php?id=4923187 Wed, 08 Jun 2011 15:45:26 +0100 4923187