MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Pediatric Dermatology' source. Wed, 08 Feb 2012 13:12:36 +0100 http://www.medworm.com/index.php?rid=5659820&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01586.x We report a 15‐year‐old boy with blastic plasmacytoid dendritic cell neoplasm who was treated with acute myeloid leukemia‐based polychemotherapy and subsequent allogenic stem cell transplantation. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5659820 Fri, 03 Feb 2012 05:00:00 +0100 5659820 http://www.medworm.com/index.php?rid=5659819&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01587.x Abstract:  Congenital anonychia is an inherited autosomal recessive disorder characterized by complete absence of fingernails or toenails, or both. In the present study, we have described a consanguineous Pakistani family having a family member affected with congenital anonychia. Genotyping using polymorphic microsatellite markers showed linkage of the family to gene RSPO4 encoding R‐spondin and mapped on human chromosome 20p13. Deoxyribonucleic acid sequence analysis of the gene identified a novel nonsense mutation (c.18C>A; p.Cys6X) in the affected family member. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5659819 Fri, 03 Feb 2012 05:00:00 +0100 5659819 http://www.medworm.com/index.php?rid=5659818&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01588.x We present four cases of children less than 2 years of age, seen in four different practices, with a similar, unique, and specific presentation of diaper dermatitis, all while using Pampers Baby Dry with Drymax™ technology. To date, no reported cases exist of allergic contact dermatitis to Pampers Dryweave™ in medical literature. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5659818 Fri, 03 Feb 2012 05:00:00 +0100 5659818 http://www.medworm.com/index.php?rid=5659817&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01589.x Abstract:  Acute genital ulcers rarely occur in nonsexually active young girls. When present, they can cause significant physical and emotional distress for the patient and her parents, and prompt an evaluation for sexual abuse and sexually transmitted diseases. With this review, we aim to further characterize acute genital ulcers in nonsexually active young girls by reviewing the medical records of patients with this disorder and to offer an approach to the diagnosis, evaluation, and treatment of acute genital ulcers based on our understanding and knowledge of this condition. We retrospectively review our understanding and knowledge of acute genital ulcers in nonsexually active girls at a pediatric hospital. A review of the recent literature on acute genital ulcers and a multidisciplina... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5659817 Fri, 03 Feb 2012 05:00:00 +0100 5659817 http://www.medworm.com/index.php?rid=5659816&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01688.x Abstract:  Nevus spilus, also known as speckled lentiginous nevus, is a nevoid disorder characterized by hyperpigmented macules or papules scattered over a background of tan pigmentation. Although nevus spilus is mainly of cosmetic concern, malignant melanoma may rarely develop in the lesions. Although classically not mentioned as a hairy nevus, a few reports in literature mention overlying hypertrichosis in lesions of nevus spilus. We hereby report four cases of nevus spilus without malignant change with overlying terminal hairs that arose mainly from the background pigmented area. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5659816 Fri, 03 Feb 2012 05:00:00 +0100 5659816 http://www.medworm.com/index.php?rid=5659815&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01695.x We report the case of an infant with novel heterozygous mutations in ABCA12 who exhibited features and a clinical course more consistent with congenital ichthyosiform erythroderma than harlequin ichthyosis. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5659815 Fri, 03 Feb 2012 05:00:00 +0100 5659815 http://www.medworm.com/index.php?rid=5659814&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01696.x Abstract:  A 7‐year‐old boy presented with an annular verrucous plaque on the chin of 5 weeks duration. The lesion occurred after a bicycle accident and was unresponsive to antibiotics. Fungal culture grew Sporothrix schenckii. Sporotrichosis should be considered and fungal culture obtained whenever a nodule or plaque fails to respond to initial treatment. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5659814 Fri, 03 Feb 2012 05:00:00 +0100 5659814 http://www.medworm.com/index.php?rid=5659813&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01700.x Abstract:  Impetigo is a common cutaneous infection that is especially prevalent in children. The prevalence of colonization and infection with resistant strains is continually increasing, forcing clinicians to reevaluate treatment strategies. Newer topical agents are effective in treating infections with resistant strains and may help minimize resistance and adverse effects from systemic agents. Use of topical disinfectants to decrease colonization is an important adjunctive measure. Physicians should be aware of local resistance patterns in impetigo to help guide therapy. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5659813 Fri, 03 Feb 2012 05:00:00 +0100 5659813 http://www.medworm.com/index.php?rid=5659812&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01554.x Abstract:  The aim of this case report was to determine the method and basic principles of immediate tissue expansion using a Foley catheter in the forehead region for treating a medium‐sized congenital melanocytic nevus. A 4‐year‐old child presented with a supraorbitally located forehead congenital melanocytic nevus, close to the midline. Total excision and reconstruction with intraoperatively expanded forehead skin below the hairline was performed. Intraoperative tissue expansion using a Foley catheter allowed us to obtain expanded and enhanced local tissue, which had tissue characteristics similar to those of the forehead skin, and thus closure of a medium‐sized defect without distorting important anatomic structures such as the brow and frontal hairline was possible. Of the t... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5659812 Fri, 03 Feb 2012 05:00:00 +0100 5659812 http://www.medworm.com/index.php?rid=5659811&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01671.x We describe the use of “Magic Goggles,” a distraction technique of use in pediatric dermatology procedures. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5659811 Fri, 03 Feb 2012 05:00:00 +0100 5659811 http://www.medworm.com/index.php?rid=5659810&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01701.x We present here a case of Trichophyton tonsurans–induced onychomycosis and resultant onychomadesis in a 9‐month‐old boy with onset of lesions at 2 weeks of life. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5659810 Fri, 03 Feb 2012 05:00:00 +0100 5659810 http://www.medworm.com/index.php?rid=5659809&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01702.x We present seven children with widespread, recalcitrant dermatitis who experienced 60–80% clearance after initiating a diet low in balsam of Peru, specifically the tomato product ketchup. Furthermore, because we have observed a high prevalence of ketchup in our pediatric patients’ diets, we recommend consideration of moderate consumption of this product in patients with recalcitrant widespread dermatitis. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5659809 Fri, 03 Feb 2012 05:00:00 +0100 5659809 http://www.medworm.com/index.php?rid=5659808&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01713.x We report a case of Spitz nevus arising in skin overlying a congenital plaque‐like glomuvenous malformation (GVM). This is the first report of a Spitz nevus arising in direct contiguity to a GVM. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5659808 Fri, 03 Feb 2012 05:00:00 +0100 5659808 http://www.medworm.com/index.php?rid=5659807&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01714.x Abstract:  A 9‐year‐old male presented to our dermatology clinic with a recent history of developing numerous cutaneous pilomatricomas, and was subsequently discovered to have sustained a recurrence of his glioblastoma multiforme. Immunohistochemical staining of a representative pilomatricoma and his original brain tumor revealed upregulation and nuclear localization of beta‐catenin, a sign associated with poor prognosis in glioblastoma. We hypothesize that the development of multiple pilomatricomas may have been a hallmark of this patient's tumor recurrence and provide support for a recent report of an association between multiple pilomatricomas and gliomatosis cerebri. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5659807 Fri, 03 Feb 2012 05:00:00 +0100 5659807 http://www.medworm.com/index.php?rid=5659806&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01717.x Abstract:  Dyshidrotic eczema is one of the rare cutaneous adverse effects of intravenous immunoglobulin therapy, usually seen in adults. We herein report the first pediatric case of severe dyshidrotic eczema occurring after intravenous immunoglobulin therapy for Kawasaki syndrome. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5659806 Fri, 03 Feb 2012 05:00:00 +0100 5659806 http://www.medworm.com/index.php?rid=5628704&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01657.x We describe the case of a 16‐year‐old girl with XP type C treated safely with photodynamic therapy (PDT). Although there is little if any evidence in the literature supporting the use of aminolevulinic acid PDT in individuals with XP, they may be the ideal candidates for PDT treatment because the profound post‐treatment photosensitivity and strict post‐therapy sun avoidance necessitated by PDT treatment is already part of the everyday lifestyle of people with XP. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5628704 Thu, 26 Jan 2012 05:00:00 +0100 5628704 http://www.medworm.com/index.php?rid=5628703&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01665.x This article details a child in Connecticut diagnosed during the winter with chilblains and microgeodic disease of his toe, as supported by biopsy and imaging. These findings further indicate that the two diseases are interrelated, imply a similar pathogenesis, and lead us to suggest similar treatment for problematic forms of both diseases. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5628703 Thu, 26 Jan 2012 05:00:00 +0100 5628703 http://www.medworm.com/index.php?rid=5628702&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01666.x We report these cases for their rarity and self‐healing nature. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5628702 Thu, 26 Jan 2012 05:00:00 +0100 5628702 http://www.medworm.com/index.php?rid=5628701&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01670.x We report herein a 10‐year‐old girl with PNP appearing a few weeks after resection of a recurrent CD. Despite improvement in skin and mucosal lesions with prednisolone and azathioprine, she had severe bronchiolitis obliterans and died from respiratory failure a few months later. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5628701 Thu, 26 Jan 2012 05:00:00 +0100 5628701 http://www.medworm.com/index.php?rid=5628700&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01660.x Abstract:  The term “ectopic nail” refers to nail tissue found in a location other than in the normal nail bed. Here we report a 9‐year‐old girl with an asymptomatic keratotic “horn” on the tip of her left fifth finger. Present since the age of 1 month, it was misdiagnosed as a common wart and treated using liquid nitrogen cryotherapy without benefit. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5628700 Thu, 26 Jan 2012 05:00:00 +0100 5628700 http://www.medworm.com/index.php?rid=5628699&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01667.x We report a 2‐month‐old boy with bilateral branchial cleft anomalies, low‐set ears, and hydronephrosis who tested positive for a mutation in the TFAP2A gene (A256V) implicated in branchio‐oculo‐facial (BOF) syndrome. Magnetic resonance imaging (MRI) revealed a thyroglossal duct cyst at the base of the tongue. To our knowledge, this is the first reported case of BOF syndrome presenting concomitantly with a thyroglossal duct cyst. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5628699 Thu, 26 Jan 2012 05:00:00 +0100 5628699 http://www.medworm.com/index.php?rid=5628698&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01662.x We report a case of MBN arising in a GCBN on the back. There have been three previous reports of MBN associated with GCBN on the trunk; our case had the earliest onset of MBN arising in a GCBN. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5628698 Thu, 26 Jan 2012 05:00:00 +0100 5628698 http://www.medworm.com/index.php?rid=5628697&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01669.x We report a case of FUMHD in an 11‐year‐old boy who subsequently developed neurologic symptoms and was found to have necrotizing vasculitis on brain biopsy. Over 5 years of follow‐up, he had one biopsy‐proven recurrence of his skin lesions and continued rehabilitation and treatment for residual neurologic complications. This case provides histological evidence of central nervous system vasculitis associated with FUMHD. Our patient’s disease was eventually controlled with cyclophosphamide. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5628697 Thu, 26 Jan 2012 05:00:00 +0100 5628697 http://www.medworm.com/index.php?rid=5628696&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01674.x Abstract:  Neonatal purpura fulminans is rare and may be inherited or acquired. It may ultimately lead to multiorgan failure and death. Purpura fulminans in a premature neonate resulting from Staphylococcus aureus septicemia is illustrated. Unfortunately, the baby succumbed to septicemia. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5628696 Thu, 26 Jan 2012 05:00:00 +0100 5628696 http://www.medworm.com/index.php?rid=5628695&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01675.x We report a case of a 9‐year‐old boy with a spontaneous mutation causing HAE, diagnosed after a life‐threatening episode of angioedema of the head and upper respiratory tract after a 5‐year history of recurrent skin swellings and abdominal pain leading to several hospital admissions. The aim of this report is to direct focus on this rare disease, which can be treated effectively, to diminish morbidity and mortality of children suffering from undiagnosed HAE. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5628695 Thu, 26 Jan 2012 05:00:00 +0100 5628695 http://www.medworm.com/index.php?rid=5628694&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01676.x We report a 7‐month‐old boy with cutaneous involvement of neonatal lupus erythematosus mimicking an extensive capillary malformation. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5628694 Thu, 26 Jan 2012 05:00:00 +0100 5628694 http://www.medworm.com/index.php?rid=5628693&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01678.x We report a case of a solitary infantile myofibroma masquerading as an ulcerated infantile hemangioma. Infantile myofibroma is a rare soft tissue tumor that has a good prognosis in the solitary form. It may be difficult to distinguish clinically from more common tumors of infancy such as an infantile hemangioma or from other rare entities and therefore requires a biopsy for definitive diagnosis. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5628693 Thu, 26 Jan 2012 05:00:00 +0100 5628693 http://www.medworm.com/index.php?rid=5659805&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01718.x We report on a 28‐year‐old man with Kabuki syndrome with three pilomatricomas in his head and thigh. Although several reports describe multiple pilomatricomas associated with Turner syndrome, there are no reports of multiple pilomatricomas combined with Kabuki syndrome. Ectodermal abnormalities such as hair abnormality and hirsutism are symptoms of Kabuki syndrome, and pilomatricomas are frequently associated with the mutations of beta‐catenin in hair follicle development. The predisposition of pilomatricomas may be not merely a coincidental finding, but an added association with Kabuki syndrome. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5659805 Sun, 01 Jan 2012 05:00:00 +0100 5659805 http://www.medworm.com/index.php?rid=5647879&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01612.x Abstract:  Complications of severe forms of epidermolysis bullosa (EB) almost invariably lead to chronic malnutrition, jeopardizing immune status, growth, iron status, bone health, wound healing, and quality of life. Although gastrostomy tube (G‐tube) feeding has successfully addressed the difficulties of providing nutrition and medications in some children attending our center, others have developed problems such as abdominal distension, poor feed tolerance, and leakage of gastric contents with persistent localized skin ulceration, posing enormous challenges to skin management and nutritional maintenance. Suspicions that G‐tube placement and feeding cause or exacerbate these problems has led to a decline in placements at our center over the last 10 years. We therefore recognized t... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5647879 Sun, 01 Jan 2012 05:00:00 +0100 5647879 http://www.medworm.com/index.php?rid=5628692&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01673.x We report a case of an 8‐year‐old girl with Down syndrome who presented with histologically verified MICC, briefly review the literature on MICC, discuss the differential diagnosis, and describe the use of dermoscopy in the evaluation of lesions, which we believe has never been published previously with this entity. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5628692 Sun, 01 Jan 2012 05:00:00 +0100 5628692 http://www.medworm.com/index.php?rid=5608916&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01720.x (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5608916 Sun, 01 Jan 2012 05:00:00 +0100 5608916 http://www.medworm.com/index.php?rid=5608915&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01685.x (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5608915 Sun, 01 Jan 2012 05:00:00 +0100 5608915 http://www.medworm.com/index.php?rid=5608914&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01679.x We present a case of an infant with an ulcerated lip hemangioma treated with an over‐the‐counter topical sealant in combination with systemic corticosteroid therapy who showed dramatic improvement in pain and tolerance to feeding, resulting in healing of the ulceration. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5608914 Sun, 01 Jan 2012 05:00:00 +0100 5608914 http://www.medworm.com/index.php?rid=5608913&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01486.x We report a case of refractory HV successfully treated with dietary fish oil rich in ω‐3 polyunsaturated fatty acids. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5608913 Sun, 01 Jan 2012 05:00:00 +0100 5608913 http://www.medworm.com/index.php?rid=5608912&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01686.x We present a case of verruciform xanthoma involving the left foot and toes of a 10‐year‐old boy who had developed a primary lymphedema (lymphedema praecox) in the left lower extremity. Laboratory studies demonstrated a normal lipid profile. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5608912 Sun, 01 Jan 2012 05:00:00 +0100 5608912 http://www.medworm.com/index.php?rid=5608911&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01635.x (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5608911 Sun, 01 Jan 2012 05:00:00 +0100 5608911 http://www.medworm.com/index.php?rid=5608910&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01625.x (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5608910 Sun, 01 Jan 2012 05:00:00 +0100 5608910 http://www.medworm.com/index.php?rid=5608909&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01623.x (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5608909 Sun, 01 Jan 2012 05:00:00 +0100 5608909 http://www.medworm.com/index.php?rid=5608908&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01691.x Abstract:  Treatment of children with severe atopic dermatitis (AD) can be especially challenging because several possible intervention treatments have (relative) contraindications in childhood. In recent years, wet‐wrap treatment (WWT) has been advocated as a relatively safe and efficacious intervention in children with severe or refractory AD. The goal of this article is to provide a practical guideline as a starting point for clinicians who are interested in using WWT in their own clinical practice. We will address several practical issues surrounding the use of WWT by describing our own experiences, supplemented with data from the literature. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5608908 Sun, 01 Jan 2012 05:00:00 +0100 5608908 http://www.medworm.com/index.php?rid=5608907&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01590.x Abstract:  Adaptation of skin barrier function and interleukin‐1α (IL‐1α) content in diapered and nondiapered skin are poorly characterized in newborns receiving standard skin care. In a monocentric, prospective pilot study 44 healthy, full‐term neonates were randomly assigned to skin care with baby wipes (n = 21) or water‐moistened washcloth (n = 23) at each diaper change. Transepidermal water loss (TEWL), skin hydration, skin‐pH, IL‐1α, and epidermal desquamation were measured on days 2, 14, and 28 postpartum. Microbiological colonization was evaluated at baseline and on day 28. Significantly lower TEWL was found on the buttock in the group using baby wipes compared to water. IL‐1α and skin hydration significantly increased and pH decreased independent of skin... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5608907 Sun, 01 Jan 2012 05:00:00 +0100 5608907 http://www.medworm.com/index.php?rid=5552324&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01584.x Abstract:  Lipodystrophia centrifugalis abdominalis infantilis is a localized lipodystrophic disease affecting young children. A total of 168 cases were collected from dermatology literature. Where possible, details of the data were also obtained from the authors. Most of the patients were Japanese, Korean, or Chinese in origin. The Caucasian patients were from England, Italy, France, Germany, Spain, and the United States. The male‐to‐female ratio was 1:1.6. The depressed lesions developed during the first 4 years of life in the groin or axilla, surrounded by a slight erythematous change. Histologically, subcutaneous fatty tissue was lost or markedly decreased in the depressed areas, and marked or moderate mononuclear cell infiltration was observed in the fatty tissue of the surrou... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5552324 Fri, 30 Dec 2011 05:00:00 +0100 5552324 http://www.medworm.com/index.php?rid=5552323&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01585.x Abstract:  Dermatomyositis is an autoimmune inflammatory myopathy characterized by unique cutaneous features. Gottron’s papules are pathognomonic, lichenoid papules that can be found overlying the joints of the dorsal hand. Papules on the palms of the hand are less commonly seen, especially in the pediatric age group. Recognition of these inverse Gottron’s papules as a sign of dermatomyositis is important as they may be the only cutaneous feature and may be a clue of underlying interstitial lung disease. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5552323 Fri, 30 Dec 2011 05:00:00 +0100 5552323 http://www.medworm.com/index.php?rid=5552322&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01591.x This article describes an otherwise typical basal cell carcinoma arising in young patient, with emphasis on histologic diagnosis. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5552322 Fri, 30 Dec 2011 05:00:00 +0100 5552322 http://www.medworm.com/index.php?rid=5552321&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01592.x We report two pediatric cases of irritant contact dermatitis after exposure to a rust remover, which contained ammonium bifluoride. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5552321 Fri, 30 Dec 2011 05:00:00 +0100 5552321 http://www.medworm.com/index.php?rid=5552320&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01663.x We report an additional case, followed up for 5 years, in which we excluded a pathogenic mutation in the TP63 gene. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5552320 Fri, 30 Dec 2011 05:00:00 +0100 5552320 http://www.medworm.com/index.php?rid=5552319&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01680.x Abstract:  In resource‐poor settings, scabies is associated with considerable morbidity. Which factors determine morbidity and how rapidly it recedes after specific treatment is not known. Patients with scabies were recruited in three urban slums in Fortaleza, Northeast Brazil. Diagnosis was established according to dermatoscopy, skin scraping, or adhesive film test. Severity of scabies‐associated morbidity was assessed semiquantitatively. Patients and close contacts were treated with oral ivermectin (200 μg/kg, repeated after 7 days) and followed up for 2 weeks. Ninety‐five patients were included in the study. Papules were the most common lesion type (98.9%). Excoriations due to scratching were observed in 43.2% and bacterial superinfection in 24.2%. Predilection sites were... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5552319 Fri, 30 Dec 2011 05:00:00 +0100 5552319 http://www.medworm.com/index.php?rid=5552318&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01681.x We present a case of a 12‐year‐old girl with congenital MCDF. To our knowledge, this is only the third reported case of congenital presentation of MCDF and the only case featuring atrophoderma‐like depression. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5552318 Fri, 30 Dec 2011 05:00:00 +0100 5552318 http://www.medworm.com/index.php?rid=5552317&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01692.x We report the case of a 22‐year‐old girl with a genetic predisposition to pattern hair loss who developed inveterate diffuse alopecia. The patient had onset of ALL at 8 years old and underwent bone marrow transplantation (BMT). Diffuse alopecia gradually advanced over her whole body. Her vellus scalp hair gradually came out, and hair loss progressed again at 8 years, after BMT. She later developed iatrogenic failure of secretion of estrogen and was treated with estrogen substitution therapy for 14 months from the age of 20. There was a small increase in the volume of hair during therapy, but alopecia returned to the former level after the therapy was suspended. Histopathologic examinations of the scalp performed during estrogen substitution therapy and 2 years after suspension ... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5552317 Fri, 30 Dec 2011 05:00:00 +0100 5552317 http://www.medworm.com/index.php?rid=5486918&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01411.x We report the development of eruptive vellus hair cysts on the trunk of an 8‐ and 12‐year‐old sister and brother. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5486918 Fri, 09 Dec 2011 05:00:00 +0100 5486918 http://www.medworm.com/index.php?rid=5486917&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01412.x We report the clinicopathologic findings of four Taiwanese children with LCAI in which local induration or ecchymotic changes preceded the skin depressions on the groin or abdomen. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5486917 Fri, 09 Dec 2011 05:00:00 +0100 5486917 http://www.medworm.com/index.php?rid=5486916&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01413.x We present a case of nevus lipomatosus superficialis that showed clinical and histological improvement after treatment with intralesional phosphatidylcholine and sodium deoxy‐cholate. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5486916 Fri, 09 Dec 2011 05:00:00 +0100 5486916 http://www.medworm.com/index.php?rid=5486915&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01416.x We present the case of a 10‐year‐old girl living in a child care institution with “cauliflower ear” that was interpreted as a possible sign of child abuse. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5486915 Fri, 09 Dec 2011 05:00:00 +0100 5486915 http://www.medworm.com/index.php?rid=5486914&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01417.x Abstract:  A 3‐year‐old boy presented with asymptomatic elastomas on the posterior trunk. Radiographic studies revealed osteopoikilosis, confirming the diagnosis of Buschke‐Ollendorff syndrome. The patient had a history of bilateral simple cutaneous syndactyly, which has not been previously reported with this condition. Buschke‐Ollendorff syndrome is a rare autosomal‐dominant disorder characterized by connective tissue nevi and osteopoikilosis. Several associated systemic abnormalities have been reported, but morbidity and mortality are generally not affected. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5486914 Fri, 09 Dec 2011 05:00:00 +0100 5486914 http://www.medworm.com/index.php?rid=5486913&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01619.x Abstract:  Wells’ syndrome, otherwise known as eosinophilic cellulitis, is a rare dermatosis seen more commonly in adults than in children. In this article, we present a 5‐year‐old Caucasian boy who initially presented with pruritic, erythematous macules and papules evolving to bullae formation. Subsequent histology confirmed diagnosis of Wells’ syndrome, and additional blood work also demonstrated positive immunoglobulin (Ig)M and IgG for parvovirus. In many instances, the direct etiology of Wells’ syndrome is unclear, but the link between parvoviral infection and development of Wells’ syndrome could further support an additional cause. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5486913 Fri, 09 Dec 2011 05:00:00 +0100 5486913 http://www.medworm.com/index.php?rid=5486912&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01661.x Abstract:  Patients with atopic dermatitis (AD) are predisposed to infection with Staphylococcus aureus, which worsens their skin disease; it has been postulated that the lack of antimicrobial peptides due to aberrant allergic inflammation in skin with AD could mediate this enhanced bacterial susceptibility. We sought to characterize the amounts of S. aureus and biological products found in infected AD lesions and whether treatment with topical corticosteroids and oral cephalexin as the only antimicrobial improved outcomes. Fifty‐nine children with clinically and S. aureus–positive impetiginized lesions of AD were enrolled in this study. A lesion was graded clinically using the Eczema Area and Severity Index, and wash fluid was obtained from the lesion for quantitative bacterial cu... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5486912 Fri, 09 Dec 2011 05:00:00 +0100 5486912 http://www.medworm.com/index.php?rid=5476603&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01614.x We describe a case of multiple, discrete, hypopigmented macules in the suprapubic and axillary region in a healthy 3‐year‐old girl. The lesions first appeared at approximately 9 months of age and increased in number over time. Initial histopathologic examination by an outside dermatopathologist at 1 year of age was reported as showing nonspecific histologic changes. A repeat biopsy at 3 years of age showed large intraepidermal clear cells that expressed CKAE1/CAM5.2, CK7, and BRST2. These findings are diagnostic for clear‐cell papulosis, a rare condition that primarily affects children. Without great clinical and pathologic suspicion, this is a diagnosis that can often be overlooked because the histologic findings are virtually identical to those of normal skin. (Source: Pediat... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5476603 Tue, 06 Dec 2011 05:00:00 +0100 5476603 http://www.medworm.com/index.php?rid=5476602&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01615.x We report on the efficacy of local application of propranolol ointment in superficial hemangiomas of the skin. In our outpatient department, 45 children with 65 hemangiomas were treated with 1% propranolol in a hydrophilic ointment topically applied twice a day. Before start of treatment and at each visit, clinical photographs were taken. If ultrasound did not confirm occult deeper components, children were included in the study. Treatment in the proliferative phase within the first 6 months of life (including seven preterm infants) induced regression in 59% and cessation of growth in 26% of the hemangiomas. No response or proliferation of subcutaneous components was observed in 15%. Clinically, no side effects caused by the beta‐receptor blocker were noticed. Treatment of two ulcerate... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5476602 Tue, 06 Dec 2011 05:00:00 +0100 5476602 http://www.medworm.com/index.php?rid=5476601&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01616.x Abstract:  Keratosis pilaris (KP) is a frequent and benign condition in children characterized by the presence of rough, follicular papules and varying degrees of erythema. Different variants have been described, including simple KP and red KP. Between September 2007 and October 2010, 11 children with profuse and precocious KP seen at the department of pediatric dermatology were included. They defined an underemphasized clinical variant of childhood KP: the papular, profuse, and precocious KP characterized by early age of onset (<18 mos), extensive involvement of the limbs and cheeks, and papular nature of lesions. No clinical association has been found. The main complication was episodes of folliculitis. Diagnosis was delayed for all patients. Treatment is difficult, but associatio... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5476601 Tue, 06 Dec 2011 05:00:00 +0100 5476601 http://www.medworm.com/index.php?rid=5457795&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01639.x We present a fourth case of this syndrome. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5457795 Mon, 28 Nov 2011 05:00:00 +0100 5457795 http://www.medworm.com/index.php?rid=5457794&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01649.x We report on two unrelated patients who presented with typical clinical and histologic features of HMD along with other unreported clinical findings. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5457794 Mon, 28 Nov 2011 05:00:00 +0100 5457794 http://www.medworm.com/index.php?rid=5457793&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01651.x Abstract:  Periorificial dermatitis is a common acneiform eruption that is thought to represent a variant of rosacea. These patients typically present with uniform erythematous papules most commonly located periorally but also occurring around the nose and eyelids. This eruption has been linked to topical corticosteroid use, with only a few reports in the literature associated with systemic steroid use in adults. Here, we report two cases of periorificial dermatitis occurring after systemic corticosteroid use in children. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5457793 Mon, 28 Nov 2011 05:00:00 +0100 5457793 http://www.medworm.com/index.php?rid=5457792&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01653.x Abstract:  Patterned transient pigmentation along lines of creases occurring in a newborn is rare. A case report of this entity is described, along with a review of all six cases described in the literature so far. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5457792 Mon, 28 Nov 2011 05:00:00 +0100 5457792 http://www.medworm.com/index.php?rid=5408126&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01606.x The objective of the study was to catalog hair shaft abnormalities in individuals with ectodermal dysplasia (ED) syndromes using light microscopy and to compare findings with those in unaffected controls. Light microscopy was performed in a nonblinded manner on hair shafts from 65 participants with seven types of ED (hypohidrotic ED, ED–ectrodactyly–cleft lip or palate, ankyloblepharon–ectodermal defects–cleft lip and palate, Clouston syndrome, Goltz syndrome, Schopf‐Schulz Passarge syndrome, and oculodentodigital dysplasia) and 41 unaffected controls. Hair donations were collected at the 28th Annual National Family Conference held by the National Foundation for Ectodermal Dysplasia. Control participants were recruited from a private dermatology practice and an academic children�... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5408126 Wed, 16 Nov 2011 05:00:00 +0100 5408126 http://www.medworm.com/index.php?rid=5408125&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01607.x We report a case of ulcerated lupus vulgaris occurring in 1.5‐year‐old boy at the Bacille Calmette‐Guérin vaccination site within 6 months, which was diagnosed using histology and polymerase chain reaction. The lesion resolved with isoniazid and rifampicin therapy. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5408125 Wed, 16 Nov 2011 05:00:00 +0100 5408125 http://www.medworm.com/index.php?rid=5408124&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01608.x We present two pediatric patients with pityriasis lichenoides et varioliformis acuta fulminans whose admitting diagnosis was Stevens Johnson Syndrome. The patients were successfully treated with methotrexate and prednisone. These cases highlight the importance of early recognition and treatment of this disease to prevent further morbidity and a potentially fatal prognosis. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5408124 Wed, 16 Nov 2011 05:00:00 +0100 5408124 http://www.medworm.com/index.php?rid=5408123&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01610.x Abstract:  Porokeratosis is a rare disorder of epidermal keratinization that is regarded as a precancerous. Recipients of hematopoietic stem cell transplantation (HSCT) have a greater risk of skin cancer; chronic graft versus host disease (GVHD) is an additional risk factor. A 16‐year‐old boy who had received HSCT for acute myelogenous leukemia was referred to us for sclerodermoid chronic cutaneous GVHD. Two years later, he developed disseminated porokeratosis with a few atypical lesions. Despite cryotherapy, numerous lesions of porokeratosis recurred rapidly. Acitretin resulted in good clinical response and reduced the rate of onset of new lesions. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5408123 Wed, 16 Nov 2011 05:00:00 +0100 5408123 http://www.medworm.com/index.php?rid=5408122&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01638.x Abstract:  Subcutaneous granuloma annulare (SGA) is a rarely reported subtype of granuloma annulare that occurs almost exclusively in children. The etiology of these lesions is unknown, although a possible relationship to insulin‐dependent diabetes mellitus (IDDM) has been proposed in the literature. Here we present an unusual case of SGA on the right forearm in a 3‐year‐old girl. Unlike the typical lesions noted on the extremities, on magnetic resonance imaging her lesions involved the subcutaneous tissue and adjacent muscles in multiple locations. Histopathologically, the case was consistent with SGA but was unusual in its distribution involving multiple muscles, a finding that has not been previously reported. Weeks after incisional biopsy, she was readmitted with diabetic ketoa... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5408122 Wed, 16 Nov 2011 05:00:00 +0100 5408122 http://www.medworm.com/index.php?rid=5386798&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01536.x Abstract:  We performed a prospective study of 1,000 neonates investigated in the first 72 hours of life in the health area of Ferrol (northwest of Spain) to assess the prevalence of erythema toxicum neonatorum, the anatomical sites most frequently involved, the influence of different maternal and neonatal parameters, day of life of medical examination, and type of delivery (vaginal or Cesarean). Overall prevalence of erythema toxicum neonatorum was 16.7%. Lesions most frequently involved the trunk, buttocks, and proximal areas of limbs. A higher prevalence of this dermatosis was found in Caucasian newborns (p = 0.01) and those with higher birthweight (p < 0.05), greater gestational age (p < 0.05), vaginal delivery (p < 0.05), maternal age of <30 years (p�... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5386798 Tue, 08 Nov 2011 05:00:00 +0100 5386798 http://www.medworm.com/index.php?rid=5386797&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01544.x We describe three cases of LEP in children younger than 18 and compare them to previous cases reported in the literature. We examine laboratory tests performed, biopsy results, age at onset and diagnosis, presence or absence of systemic symptoms, and outcomes after treatment. It is unknown what the risk is of these patients developing future systemic lupus erythematosus. We also discuss the relevance of subcutaneous panniculitis‐like T‐cell lymphoma, because the clinical and pathologic pictures are similar in presentation. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5386797 Tue, 08 Nov 2011 05:00:00 +0100 5386797 http://www.medworm.com/index.php?rid=5386796&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01552.x Abstract:  Hematuria is defined as the abnormal presence of red blood cells in the urine and is commonly divided into gross and microscopic hematuria. Terminal hematuria occurs at the end of the urine stream and may have a prostatic, bladder, or trigonal cause. Here, we present a 16‐year‐old boy who developed terminal hematuria after 1 month of treatment with isotretinoin for acne vulgaris. This side effect of isotretinoin is not reported in the literature. This is the first case report. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5386796 Tue, 08 Nov 2011 05:00:00 +0100 5386796 http://www.medworm.com/index.php?rid=5386795&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01553.x We report a 16‐year‐old boy with two Becker’s nevi on the left side of the face in a segmental distribution with extension onto the oral mucosa. This case is being reported for its rare presentation. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5386795 Tue, 08 Nov 2011 05:00:00 +0100 5386795 http://www.medworm.com/index.php?rid=5386794&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01560.x We report a case of atypical molluscum contagiosum accompanied by atypical lymphocytic infiltration showing CD30 positivity. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5386794 Tue, 08 Nov 2011 05:00:00 +0100 5386794 http://www.medworm.com/index.php?rid=5386793&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01561.x We report here a case of a child whose diagnosis was made retrospectively but with good outcome. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5386793 Tue, 08 Nov 2011 05:00:00 +0100 5386793 http://www.medworm.com/index.php?rid=5386792&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01563.x We report a new APSS pedigree from Jordan that contains at least 10 affected family members, although sequencing of the TGM5 gene failed to disclose any pathogenic mutation(s). On the basis of probable consanguinity, we performed homozygosity mapping and identified areas of homozygosity on chromosomes 1, 6, 10, 13, and 16, although none of the intervals contained genes of clear relevance to cornification. APSS is a clinically and genetically heterogeneous disorder, and this Jordanian pedigree underscores the likelihood of still further heterogeneity. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5386792 Tue, 08 Nov 2011 05:00:00 +0100 5386792 http://www.medworm.com/index.php?rid=5386791&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01565.x We report three infants who developed agminated pyogenic granulomas over congenital vascular malformations, all of which had an aggressive growth pattern. There were no precipitating events such as laser therapy or surgery. Lesions were excised. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5386791 Tue, 08 Nov 2011 05:00:00 +0100 5386791 http://www.medworm.com/index.php?rid=5386790&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01566.x We describe a MNTI arising in the anterior maxilla of a 6‐month‐old boy. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5386790 Tue, 08 Nov 2011 05:00:00 +0100 5386790 http://www.medworm.com/index.php?rid=5386803&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01573.x The objective of this study was to determine the clinical patterns of the mucocutaneous manifestations during and after chemotherapy in children with a hematologic malignancy and to determine whether nutritional status influences the clinical presentation. We recruited patients aged 6 months to 16 years diagnosed with leukemia and lymphoma from a pediatric hematology outpatient clinic between November 2008 and May 2010. The patients were divided into two groups: Group 1, recently diagnosed patients, included in the study before receiving chemotherapy, and Group 2, patients in surveillance who had not had chemotherapy for at least 3 months. A dermatologic examination was performed, and biopsy and mycological and bacteriological tests were conducted if necessary, with 6 months of fol... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5386803 Wed, 02 Nov 2011 04:00:00 +0100 5386803 http://www.medworm.com/index.php?rid=5386802&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01574.x We present a case of a Haitian girl who presented with transverse melanonychia involving all 10 fingernails in the setting of hyperthyroidism and acute liver injury. Melanonychia has been described only one time in the literature in the setting of hyperthyroidism though this patient also underwent radium treatment which could have led to nail changes. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5386802 Wed, 02 Nov 2011 04:00:00 +0100 5386802 http://www.medworm.com/index.php?rid=5386801&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01576.x Abstract:  Montelukast was effective in treating refractory abdominal and urinary symptoms in a child with systemic mastocytosis. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5386801 Wed, 02 Nov 2011 04:00:00 +0100 5386801 http://www.medworm.com/index.php?rid=5386800&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01577.x We report the case of a 5‐year‐old boy with SDRIFE after systemic administration of amoxicillin‐clavulanate. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5386800 Wed, 02 Nov 2011 04:00:00 +0100 5386800 http://www.medworm.com/index.php?rid=5386799&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01609.x We report a case of two sisters with AWP in whom CF has not been diagnosed and review the literature on AWP and its association with CF and CF carrier status. Because diagnosis of mild forms CF or knowledge of an underlying CF genetic mutation is frequently unknown, identification of AWP may represent the only sign of such mutations. The dermatologist plays an integral role in early detection of AWP, and the importance of genetic testing in such patients cannot be overlooked. We recommend various measures to apply in clinical practice to ensure diagnosis and decrease morbidity and mortality in patients. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5386799 Wed, 02 Nov 2011 04:00:00 +0100 5386799 http://www.medworm.com/index.php?rid=5552316&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01699.x We report one of the largest series of children with AST treated using excision alone and who remain disease free after a significant follow‐up period. Our data suggest that SLNB is not warranted in the routine management of pediatric AST. We recommend complete excision with clear margins and careful clinical follow‐up. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5552316 Tue, 01 Nov 2011 04:00:00 +0100 5552316 http://www.medworm.com/index.php?rid=5486911&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01664.x This study is an extension of a previously published pilot study designed to further investigate the efficacy and safety and to identify predictors of good response of topical 0.5% or 0.1% timolol maleate gel‐forming solution. This was a retrospective cohort study including patients enrolled from five centers. Patients were included if they were treated with timolol maleate 0.1% or 0.5% gel‐forming solution and had photographic documentation of the IH and at least one follow‐up visit. Patients with concomitant active treatment using other IH treatments were excluded. The primary endpoint was change in the appearance of IH as evaluated using a visual analog scale (VAS). Data from 73 subjects were available for final analysis. Timolol maleate gel‐forming solution 0.5% was used in 85%... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5486911 Tue, 01 Nov 2011 04:00:00 +0100 5486911 http://www.medworm.com/index.php?rid=5476600&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01636.x Abstract:  A 19‐month‐old boy was evaluated for a skin eruption after recent vaccinations. Clinical and histopathologic findings supported a diagnosis of Gianotti–Crosti syndrome (GCS). This case report examines the link between GCS and vaccinations, particularly the diphtheria, tetanus, and pertussis vaccine and the varicella virus live vaccine. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5476600 Tue, 01 Nov 2011 04:00:00 +0100 5476600 http://www.medworm.com/index.php?rid=5457791&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01658.x Abstract:  Subcutaneous panniculitis‐like T‐cell lymphoma is an uncommon form of CD8‐positive cytotoxic T‐cell lymphoma of the skin that predominantly affects the subcutaneous tissue and is extremely rare in early childhood (<3 yrs). Here, we present an early pediatric case with an indolent form of subcutaneous panniculitis‐like T‐cell lymphoma occurring at 12 months old. The subcutaneous nodules gradually disappeared spontaneously, and the girl showed excellent prognosis with no aggressive treatment. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5457791 Tue, 01 Nov 2011 04:00:00 +0100 5457791 http://www.medworm.com/index.php?rid=5441100&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01564.x Abstract:  The aim of this study was to investigate the prevalence of Pediculus humanus capitis and the coexistence of intestinal parasites in boarding primary schools in Sivas, Turkey. Seven hundred seventy‐two students (350 [45.3%] girls, 422 [54.7%] boys) were evaluated with combing for the presence of head lice, collection of fecal samples, and examination of the perianal region for intestinal parasites using the cellophane tape method. The overall infestation rate for head lice was 6% (n = 46). Nine children had evidence of nits only (1.2%), whereas living lice and nits or eggs were found in 37 children (4.8%). Girls were significantly more commonly infested (12.9%) than boys (0.2%). Of the parameters evaluated, socioeconomic level, number of rooms per family, and size and wei... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5441100 Tue, 01 Nov 2011 04:00:00 +0100 5441100 http://www.medworm.com/index.php?rid=5408139&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01602.x (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5408139 Tue, 01 Nov 2011 04:00:00 +0100 5408139 http://www.medworm.com/index.php?rid=5408138&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01601.x (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5408138 Tue, 01 Nov 2011 04:00:00 +0100 5408138 http://www.medworm.com/index.php?rid=5408137&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01600.x (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5408137 Tue, 01 Nov 2011 04:00:00 +0100 5408137 http://www.medworm.com/index.php?rid=5408136&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01640.x We present a case of allergic contact dermatitis in an 18‐month‐old boy caused by type‐IV allergy to mercapto mix and mercaptobenzothiazole as components of the elastic border of diapers. Allergic contact dermatitis should be included in the differential diagnosis of diaper dermatitis, especially in difficult‐to‐treat cases or atypical clinical presentation. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5408136 Tue, 01 Nov 2011 04:00:00 +0100 5408136 http://www.medworm.com/index.php?rid=5408135&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01605.x (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5408135 Tue, 01 Nov 2011 04:00:00 +0100 5408135 http://www.medworm.com/index.php?rid=5408134&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01604.x (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5408134 Tue, 01 Nov 2011 04:00:00 +0100 5408134 http://www.medworm.com/index.php?rid=5408133&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01603.x (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5408133 Tue, 01 Nov 2011 04:00:00 +0100 5408133 http://www.medworm.com/index.php?rid=5408132&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01655.x We report here an individual with PPK with only cutaneous signs and confirm this distinctive syndrome has two subtypes according to the presence or absence of extracutaneous involvement. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5408132 Tue, 01 Nov 2011 04:00:00 +0100 5408132 http://www.medworm.com/index.php?rid=5408131&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01656.x Abstract:  We herein report a 12‐year‐old boy with amoxicillin‐induced, recurrent, site‐specific, symmetrical, sharply demarcated reddish plaques on the buttocks and the major flexural and intertriginous areas. The lesions resolved with topical corticosteroids, leaving hyperpigmentation. Histopathology showed nonspecific features of inflammation and dermal melanophages. Amoxicillin was the probable inducer based on oral provocation test with Amoksina® tablet, however patch testing with amoxicillin on previously affected and unaffected skin remained negative. The diagnosis was challenging because of the overlapping features of symmetrical drug‐related intertriginous and flexural exanthema and fixed drug eruption. This one represents a unique and challenging one with overlapping... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5408131 Tue, 01 Nov 2011 04:00:00 +0100 5408131 http://www.medworm.com/index.php?rid=5408130&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01637.x We describe a novel homozygous mutation, 1191insC, in SLC39A4 in a patient from Sierra Leone and suggest that AE should be considered within the differential diagnosis for acrodermatitis in children from Sierra Leone. Genetic testing for this founder mutation can be easily performed for this treatable disorder. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5408130 Tue, 01 Nov 2011 04:00:00 +0100 5408130 http://www.medworm.com/index.php?rid=5408129&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01644.x We describe five cases of IH recurrence after propranolol treatment was stopped in 26 patients treated with propranolol all of whom were observed for at least 9 months after treatment was discontinued. Recurrence was present in 5 of 26 cases, yielding a recurrence rate of 19%. All cases were in females. Time from withdrawal to recurrence ranged from 0 to 6 months. In four of five cases, the lesion relapsed after the age of 11 months. Four of the five cases presented partial recurrences, whereas in one case, recurrence was complete. In the majority of cases, recurrence appeared in the deep component of the IH. Early treatment withdrawal or a long proliferative phase of IH are potential causes of hemangioma recurrence, although the exact mechanism remains unclear. The vascular endothelia... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5408129 Tue, 01 Nov 2011 04:00:00 +0100 5408129 http://www.medworm.com/index.php?rid=5408128&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01645.x Abstract:  Kerion celsi is the inflammatory extreme of tinea capitis, representing a delayed hypersensitivity reaction to the causative dermatophyte. Some authors have advocated the use of oral corticosteroids in patients with kerion formation to inhibit the host inflammatory response and minimize the risk of scarring. This retrospective study analyzed the management and outcome of all children younger than 10 years old presenting to our pediatric dermatology service with tinea capitis resulting in kerion formation between 2003 and 2009. We propose that kerion treatment be directed toward the underlying dermatophyte. Oral and intralesional corticosteroids are an unnecessary adjunct to oral antifungal therapy for children with tinea capitis presenting with kerion in urban areas. (Source... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5408128 Tue, 01 Nov 2011 04:00:00 +0100 5408128 http://www.medworm.com/index.php?rid=5408127&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01643.x The objective of the current study was to assess changes in the onset of pubertal maturation by determining whether acne is occurring at an earlier age. We assessed the age at which acne is occurring by assessing trends in the age of people seeking medical attention for acne. The National Ambulatory Medical Care Survey database was used to analyze physician visits for acne vulgaris in children aged 6 to 18 from 1979 to 2007. The data were used to assess trends in the mean age of children with acne and to compare these trends according to race and sex. Regression analysis revealed a significant decrease in the mean age of children seeking treatment for acne over this 28‐year period (p < 0.001). There was no significant change in the mean age of black children seeking treatment for ... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5408127 Tue, 01 Nov 2011 04:00:00 +0100 5408127 http://www.medworm.com/index.php?rid=5408121&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01654.x Abstract:  Severe cases of atopic dermatitis (AD) may require systemic immunosuppression to achieve disease control. Unfortunately, some cases continue to be refractory to management or develop unacceptable adverse effects. There are limited reports of the use of intravenous immunoglobulin (IVIg) in the treatment of severe AD, but results are inconsistent. In a retrospective study, we report 10 children with severe AD refractory to systemic immunosuppression and maximal topical therapy who were treated using IVIg. The children received monthly IVIg for an average of 24 months. This resulted in a significant improvement in symptoms, with fewer infection‐related exacerbations and hospitalizations, allowing systemic immunosuppression to be tapered. The effect was associated with a signi... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5408121 Tue, 01 Nov 2011 04:00:00 +0100 5408121 http://www.medworm.com/index.php?rid=5335875&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01425.x This article describes a patient with the G12R mutation and KID syndrome with interesting additional features, which include a porokeratotic eccrine ostial and dermal duct nevus, follicular occlusion triad, and unusual persistent oral mucosal papules. We compare this patient’s phenotype with the only two other patients described with the same (G12R) mutation. The phenotypic heterogeneity of KID syndrome, inexplicable according to our current understanding of these proteins, speaks to the complexity of the connexin system and its overlapping expression patterns in different tissues. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5335875 Thu, 20 Oct 2011 04:00:00 +0100 5335875 http://www.medworm.com/index.php?rid=5335874&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01484.x We report a newborn with striking unilateral sebaceous hyperplasia and suggest that this may represent a unique sebaceous hamartoma rather than “premature sebaceous hyperplasia.” (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5335874 Thu, 20 Oct 2011 04:00:00 +0100 5335874 http://www.medworm.com/index.php?rid=5335873&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01533.x Abstract:  P‐tert‐butylphenol formaldehyde resin (PTBPFR) is recognized as a significant source of allergic contact dermatitis in adults and children in association with athletic gear, shoes, and neoprene. To our knowledge, this is the first case report of allergic contact dermatitis with PTBPFR associated with padded foam bras. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5335873 Thu, 20 Oct 2011 04:00:00 +0100 5335873 http://www.medworm.com/index.php?rid=5335872&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01534.x The objective of this study was to describe the clinical features of Sweet syndrome in children. Our study population consisted of seven children diagnosed with Sweet syndrome over a 22‐year period. Age, sex, appearance and location of lesions, associated signs and symptoms, past medical history, pathology, and subsequent disease course were documented for each patient. Fever and typical lesions were reported in most of patients in our study. The majority of patients presented with less‐typical findings, such as pustules, vesicles, bullae, oral ulcerations, atrophic scars, and evidence of pathergy. Of the seven children in our study, four were found to have a preceding nonspecific upper respiratory or gastrointestinal infection, and two were diagnosed with an underlying hematologic mal... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5335872 Thu, 20 Oct 2011 04:00:00 +0100 5335872 http://www.medworm.com/index.php?rid=5335871&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01538.x We report a case of sporadic pediatric‐onset KLC with seborrheic dermatitis‐like lesions on the forehead, papules in a retiform pattern in the axillae and mons pubis, and eye and oral mucosal involvement,with additional features of premature canities and a transient photosensitive eruption. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5335871 Thu, 20 Oct 2011 04:00:00 +0100 5335871 http://www.medworm.com/index.php?rid=5335870&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01539.x We describe the case of a 7‐year‐old boy with urticaria, fever, and arthritis that appeared 10 days after starting cefditoren therapy for acute tonsillopharyngitis, which was diagnosed as a serum sickness‐like reaction due to this medication. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5335870 Thu, 20 Oct 2011 04:00:00 +0100 5335870 http://www.medworm.com/index.php?rid=5335869&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01540.x We report the case of a 2‐year‐old girl with the clinical features of PHACE with absence of bilateral internal carotid arteries and isolated growth hormone deficiency. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5335869 Thu, 20 Oct 2011 04:00:00 +0100 5335869 http://www.medworm.com/index.php?rid=5335868&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01542.x Abstract:  Genital herpes simplex virus (HSV) is a sexually transmitted infection that can be transmitted from mother to child in utero, perinatally, or postnatally. Cutaneous infection with HSV commonly presents as vesicles affecting the skin, eyes, or mouth. In our case, we report a well child with cutaneous hypopigmented patches at birth that preceded typical blistering. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5335868 Thu, 20 Oct 2011 04:00:00 +0100 5335868 http://www.medworm.com/index.php?rid=5335867&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01555.x We report a rare case of blue rubber bleb nevus syndrome with gastrointestinal and central nervous system involvement. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5335867 Thu, 20 Oct 2011 04:00:00 +0100 5335867 http://www.medworm.com/index.php?rid=5335866&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01556.x We report a case of trauma‐associated bullous pemphigoid presenting in a 15‐year‐old boy with Crohn’s disease while on immunosuppressive therapy. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5335866 Thu, 20 Oct 2011 04:00:00 +0100 5335866 http://www.medworm.com/index.php?rid=5335865&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01557.x We report this case of paraneoplastic pemphigus secondary to Castleman’s syndrome confounded by herpes simplex virus‐1 positive mucosal erosions. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5335865 Thu, 20 Oct 2011 04:00:00 +0100 5335865 http://www.medworm.com/index.php?rid=5335864&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01558.x We report the first pediatric case of drug reaction with eosinophilia and systemic symptoms associated with azithromycin use in the setting of acute Epstein‐Barr virus infection in an 8‐year‐old boy. Our patient presented with fever, cutaneous eruption, eosinophilia, and hypotension requiring intensive care unit admission. He was discharged in good condition without any long‐term sequelae. This case underscores the importance of timely and accurate diagnosis of acute viral infections and appropriate use of antibiotics as well as recognition of the clinical signs of drug reaction with eosinophilia and systemic symptoms. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5335864 Thu, 20 Oct 2011 04:00:00 +0100 5335864 http://www.medworm.com/index.php?rid=5335863&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01559.x We report a case of a 7‐year‐old Japanese boy who showed moderate repigmentation and worsened freckles after using topical tacalcitol to treat a vitiligo lesion on and around the left eyelid. Topical tacalcitol might have induced and worsened the freckles, because the changes occurred during treatment. Dermatologists should be aware that topical application of tacalcitol to the cheeks can cause freckling and worsen existing freckles, in predisposed children, as described here. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5335863 Thu, 20 Oct 2011 04:00:00 +0100 5335863 http://www.medworm.com/index.php?rid=5335862&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01594.x Abstract:  In recent years, there have been continuing efforts to understand the effects of baby skin care routines and products on the healthy development of baby skin. Such efforts aim ultimately to determine the best infant skin care practices. The pediatric and dermatologic communities have not reached consensus on what constitutes an appropriate cleansing practice. In the United States, guidelines for neonatal skin care have been developed, propagated, and implemented. The accumulated knowledge has promoted evidence‐based clinical practices and, therefore, may help to improve clinical outcomes, although these guidelines primarily cover the care of preterm newborns and the treatment of those with other health problems. High‐level, long‐term clinical evidence of the effective an... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5335862 Thu, 20 Oct 2011 04:00:00 +0100 5335862 http://www.medworm.com/index.php?rid=5335861&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01595.x Abstract:  Dermatophytoses are frequent in children, but involvement of the facial skin has peculiar aspects that should be considered a separate entity: tinea faciei. Microsporum canis infection in tinea faciei has not been widely documented. To review cases of tinea faciei due to M. canis in children diagnosed at the Dermatology Clinic, University of Cagliari. Between 1990 and 2009, all children with dermatophyte infections of the facial skin were recruited for the study after parental consent. Diagnosis was made through direct microscopic and cultural examination. Age, sex, clinical form, illness duration, identified dermatophyte, source of infection, and treatment were recorded. Forty‐six cases of tinea faciei due to M. canis in children aged 11 months to 15 years (29 male/17... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5335861 Thu, 20 Oct 2011 04:00:00 +0100 5335861 http://www.medworm.com/index.php?rid=5335860&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01596.x Abstract:  A healthy 10‐year‐old girl was referred for evaluation of patchy hair loss on the scalp of longer than 6 months duration. She had been diagnosed and treated for head lice approximately 1 month before onset of the hair loss. Examination of the scalp showed discrete ovoid patches of hair loss at the vertex scalp. A scrape of the area of hair loss was performed, and a nit was visible on microscopic examination. Focal hair loss may represent an atypical manifestation of ongoing pediculosis capitis. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5335860 Thu, 20 Oct 2011 04:00:00 +0100 5335860 http://www.medworm.com/index.php?rid=5335859&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01597.x We describe a child presenting with SS and postinflammatory elastolysis who subsequently developed aortitis complicated by aortic dilatation requiring surgical intervention. Histologic features of the aorta were consistent with Takayasu arteritis (TA). Our case and previously reported cases of pediatric SS complicated by aortitis all demonstrate striking clinical similarities in that all have been associated with postinflammatory elastolysis of involved skin and aneurysmal dilation of the thoracic aorta. We propose that TA should be considered one of the disease associations of SS when complicated by postinflammatory elastolysis and that early referral for cardiovascular screening be considered in this group of patients. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5335859 Thu, 20 Oct 2011 04:00:00 +0100 5335859 http://www.medworm.com/index.php?rid=5335858&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01598.x Abstract:  Diagnosis of tinea capitis (TC) can be challenging for dermatologists, especially in noninflammatory TC caused by anthropophilic dermatophytes and in black patients, in whom erythema of the scalp is difficult to appreciate. The finding of a typical TC dermoscopic pattern may lead more quickly to a correct diagnosis. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5335858 Thu, 20 Oct 2011 04:00:00 +0100 5335858 http://www.medworm.com/index.php?rid=5314577&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01399.x We report a case of hydroa vacciniforme‐like skin eruptions with chronic active Epstein–Barr virus infection in a 16‐year‐old boy. The patient had repeated episodes of vesiculo‐necrotic eruptions on the face, trunk, and extremities for 13 years. General symptoms included fever, splenomegaly, and abnormal liver function. Histopathological examination of skin biopsy specimen demonstrated dense infiltration of lymphocytes, histocytes, and some neutrophils and plasma cells in the dermis. Immunohistochemical stain revealed that the lymphocytes were positive for T cell and B cell markers. Epstein–Barr virus infection studies and systemic presentation confirmed the diagnosis. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5314577 Thu, 13 Oct 2011 04:00:00 +0100 5314577 http://www.medworm.com/index.php?rid=5314576&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01403.x We describe a 7‐month‐old girl with a novel combination of symmetrical congenital circumferential skin folds, dysmorphic features, and multiple congenital abnormalities. Examination of the patient revealed symmetrical congenital circumferential skin folds and dysmorphic features, as well as multiple congenital anomalies including nasal pyriform aperture stenosis, ventricular septal defect, absent spleen, camptodactyly, and severe psychomotor retardation. Skin biopsy demonstrated subcutaneous fat extending into the superficial and deep reticular dermis. Sequencing of the CDON, SHH, ZIC2, SIX3, and TGIF genes (associated with holoprosencephaly) did not disclose pathogenic alterations. Extensive review of previously described cases of syndromic congenital circumferential skin folds did no... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5314576 Thu, 13 Oct 2011 04:00:00 +0100 5314576 http://www.medworm.com/index.php?rid=5314575&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01418.x Abstract:  A 10‐year‐old boy with Hunter syndrome and extensive typical skin lesions underwent 9 months of enzyme replacement therapy, after which the skin lesions disappeared. We believe that treatment with idursulfase probably removes the cutaneous storage of glucosaminoglycans in Hunter syndrome. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5314575 Thu, 13 Oct 2011 04:00:00 +0100 5314575 http://www.medworm.com/index.php?rid=5314574&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01433.x Abstract:  We performed a descriptive survey of 1,000 consecutive newborns cared for in the first 3 days of life in the health area of Ferrol (in northwest Spain) to assess the prevalence and most‐frequent locations of oral cysts and milia and to study the influence of different maternal and neonatal parameters in the development of these lesions. Prevalence of palatal, gingival, and cutaneous cysts was 53.7%, 13.4%, and 16.6%, respectively. Milia were predominantly located on the cheeks, chin, and forehead. We found a frequent association between palatal and gingival cysts but not between oral cysts and milia. Neonatal factors such as sex, weight at birth, and gestational age can significantly influence the development of palatal and gingival cysts. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5314574 Thu, 13 Oct 2011 04:00:00 +0100 5314574 http://www.medworm.com/index.php?rid=5314573&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01435.x We report a case of congenital MC in a baby born to a mother with chorioamnionitis. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5314573 Thu, 13 Oct 2011 04:00:00 +0100 5314573 http://www.medworm.com/index.php?rid=5314572&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01436.x We report a pediatric patient with focal dermal hypoplasia syndrome who developed painful excessive granulation tissue refractory to traditional medical and surgical therapies. Complete response was achieved rapidly with a combination of photodynamic therapy and intralesional steroid injections. The patient has remained in remission for longer than a year. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5314572 Thu, 13 Oct 2011 04:00:00 +0100 5314572 http://www.medworm.com/index.php?rid=5314571&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01437.x We present an 11‐year‐old boy with livedo reticularis (LR) secondary to amantadine treatment for his attention deficit hyperactivity disorder (ADHD). We are unaware of previous reports of amantadine‐induced LR associated with treatment for ADHD in the pediatric population. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5314571 Thu, 13 Oct 2011 04:00:00 +0100 5314571 http://www.medworm.com/index.php?rid=5314570&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01470.x Abstract:  Two unrelated girls presented with multiple disseminated, paired, small café‐au‐lait spots and hypopigmented macules, suggesting didymosis (twin spotting). The girls also had growth retardation, microcephaly, hypertelorism, triangular facies, and a 46,XY, r(15) karyotype. The term cutis tricolor parvimaculata has been proposed to describe a twin spot phenomenon characterized by small, paired hypochromic and hyperchromic macules on a background of normal intermediate‐pigmented skin. It has been hypothesized that the underlying gene locus of this phenomenon is a hot spot for postzygotic recombination, resulting in multiple pigmentary twin spots. Future clinical research may show whether analogous “simple” twin‐spot phenotypes in the form of cutis tricolor parvimacul... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5314570 Thu, 13 Oct 2011 04:00:00 +0100 5314570 http://www.medworm.com/index.php?rid=5314569&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01505.x Abstract:  Two hundred forty‐seven healthy newborns were investigated in a prospective cohort descriptive study. Information on phenotype and obstetric and parental history was collected. A positive association was found between erythema toxicum neonatorum and season of birth (spring and summer), whereas parental history of any skin disease was related to a lower frequency of this eruption. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5314569 Thu, 13 Oct 2011 04:00:00 +0100 5314569 http://www.medworm.com/index.php?rid=5314568&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01506.x Abstract:  Progressive macular hypomelanosis (PMH) is a condition of unknown etiology characterized by asymptomatic, hypopigmented macules located predominantly on the trunk. We recorded 12 adolescents with PMH over a 6‐month period. Ten were female, and the mean age was 16.6 years. The average time from the patients first noticing pigment change to diagnosis was 15 months. PMH is probably an underdiagnosed condition. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5314568 Thu, 13 Oct 2011 04:00:00 +0100 5314568 http://www.medworm.com/index.php?rid=5314567&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01383.x We report the case of a 15‐year‐old boy with giant congenital melanocytic nevi on his back, buttocks, and rear of the two proximal thirds of his thighs, and neurocutaneous melanosis, diagnosed when he was 3 years old. Three melanocytic nodules were present in the giant nevi that were suspected to have malignant degeneration. A biopsy of these nodules was carried out, and histological study revealed benign proliferative melanocytic nodules within the giant congenital melanocytic nevi. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5314567 Thu, 13 Oct 2011 04:00:00 +0100 5314567 http://www.medworm.com/index.php?rid=5314566&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01517.x We present two case reports of CH in which severe bleeding episodes occurred during the first weeks of life and report the use of topical tranexamic acid to control bleeding in this setting. Patient 1 was a full‐term female infant who presented at birth with a large 7‐ by 6‐cm CH of the forehead showing a few millimeter‐sized crusts. No active treatment except close follow‐up was advised. At 10 weeks of age, the size of the lesion having spontaneously decreased more than 50%, she presented with severe bleeding from a small crusted area. The bleeding was controlled using topical tranexamic acid, and except for a few minor, easily controlled bleeding episodes in the following weeks, the lesion regressed more than 80%. Patient 2 was a full‐term male infant seen at 1 day of lif... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5314566 Thu, 13 Oct 2011 04:00:00 +0100 5314566 http://www.medworm.com/index.php?rid=5314565&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01519.x Abstract:  Lindane is an organochloride pesticide, first introduced as a scabicide for human use in the 1950s (1). Because of its low cost and efficacy, it quickly became a first‐line treatment for scabies and head lice, but not long after its use became widespread, its safety was called into question, primarily regarding its neurotoxic effects. We intend to show through review of the literature and databases that lindane has been associated with numerous severe and fatal adverse reactions. This review will summarize 67 cases of adverse reactions and deaths associated with the medical use of lindane. Many of the most serious events and fatalities occurred in pediatric and geriatric populations. We concede that toxicity frequently arises from misuse, but labeled usage of lindane caused ... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5314565 Thu, 13 Oct 2011 04:00:00 +0100 5314565 http://www.medworm.com/index.php?rid=5314564&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01521.x We report a series of anti‐TNF‐α‐induced psoriasis in children with juvenile idiopathic arthritis or inflammatory bowel disease treated at a large children’s hospital. All five patients presented with severe scalp involvement. One child was treated with adalimumab for juvenile idiopathic arthritis, and four received infliximab for inflammatory bowel disease. The five patients developed psoriasis 2 to 10 months after initiating anti‐TNF‐α therapy. They presented with erythematous, scaly, crusted scalp lesions. Three of the five patients were initially treated with griseofulvin for presumed tinea capitis. The anti‐TNF‐α agent was discontinued at the time of diagnosis in two cases. Topical steroids were the mainstay of psoriasis therapy, with improvement in four of five p... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5314564 Thu, 13 Oct 2011 04:00:00 +0100 5314564 http://www.medworm.com/index.php?rid=5314563&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01535.x Abstract:  Tinea faciei (TF) is a common clinical form of tinea in children that is frequently misdiagnosed and treated with corticosteroids. No large case series of TF focusing on children have been published. The aim of this study was to analyze the main epidemiologic, clinical, and microbiologic features of TF in children over a period of 30 years and compare these features with those of other tineas. We undertook a retrospective study of 818 cases of tinea in children at a referral hospital in southern Spain, diagnosed between 1977 and 2006, concentrating for this study on TF. Of the 73 cases of TF diagnosed, 50.7% were in girls. Most children (46.6%) were 4 to 9 years old. At the time of diagnosis, 29.2% of the cases had been treated with topical steroids. The most frequently is... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5314563 Thu, 13 Oct 2011 04:00:00 +0100 5314563 http://www.medworm.com/index.php?rid=5314562&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01537.x We describe a case series of a new cutaneous iatrogenic complication of CPAP. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5314562 Thu, 13 Oct 2011 04:00:00 +0100 5314562 http://www.medworm.com/index.php?rid=5314561&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01551.x Abstract:  The goal of the current study was to compare the clinical effectiveness of oral propranolol with that of oral prednisone in the treatment of infantile hemangiomas (IH). Patients treated for IH with oral propranolol were retrospectively matched with patients treated with oral prednisone according to type, location, and size of the IH and age at start of treatment. Response to treatment was evaluated by rating serial medical photographs taken 1, 2, and 6 months after initiation of treatment. Degree of clinical improvement in overall appearance (including color and size) was rated as follows: worse or stable (0), slight (<25%), moderate (25–50%), good (50–75%), or excellent (>75%). A second assessment was done using a 100‐mm visual analog scale to rate improvement a... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5314561 Thu, 13 Oct 2011 04:00:00 +0100 5314561 http://www.medworm.com/index.php?rid=5314560&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01471.x We report a 9‐year‐old girl with exfoliative erythroderma secondary to plaque‐type psoriasis who developed hypothalamic–pituitary–adrenal axis suppression resulting from topical treatment with a medium‐potency glucocorticoid. This case emphasizes the need for awareness of this potentially life‐threatening complication of topical glucocorticoid use, particularly in patients who have significant compromise of barrier function secondary to widespread skin disease. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5314560 Thu, 13 Oct 2011 04:00:00 +0100 5314560 http://www.medworm.com/index.php?rid=5314559&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01568.x The objective was to identify the incidence of IH in an Australian neonatal population and characterize the risk factors. All women who presented to the postnatal ward in a 200‐bed maternity hospital were asked to complete a questionnaire. Details of maternal history and birth details were recorded. Two follow‐up emails 3 and 6 weeks after discharge were sent to all mothers who consented, asking if their baby had developed an IH. Babies reported to have an IH were seen in clinic to confirm the diagnosis. Details were collected from 1,034 mothers of 1,065 babies; 28 (2.6%) of the infants developed IH. Babies that developed IH were more likely to be female (p < 0.001), have a low birth weight (p = 0.020), be born at a gestational age of <37 weeks (p = 0.005), and be... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5314559 Thu, 13 Oct 2011 04:00:00 +0100 5314559 http://www.medworm.com/index.php?rid=5314558&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01562.x Abstract:  Nevus sebaceous of Jadassohn is a hamartoma with a combination of abnormalities of the epidermis, hair follicles, and sebaceous and apocrine glands. Herein, we discuss the results of an extensive literature review on the topic of nevus sebaceous with a particular focus on the debate about the necessity for prophylactic excision. We also focus on the documentation of associated malignant tumors that were reported to develop within NS. In addition to reporting the number and types of neoplasms, we documented the recommendations of all authors for therapeutic handling of these nevi. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5314558 Thu, 13 Oct 2011 04:00:00 +0100 5314558 http://www.medworm.com/index.php?rid=5314557&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01569.x This study reports the observations after completed propranolol therapy in 55 patients. Propranolol was administered in a dosage of 2 mg/kg per day with initial monitoring of vital signs. Therapy duration was planned for 4 to 6 months; if there was significant relapse, the period of treatment was extended. The mean age of 55 patients at the beginning of the treatment was 6 months (52.7% <4 mos, 30.9% 4–9 mos, 16.3% >9 mos). Thirteen patients (21.7%) showed a reaction possibly due to the medication, but we did not observe any life‐threatening adverse effects. The therapy was interrupted due to temporary aggravation of preexisting bronchial asthma in one child. The initially administered dosage was adjusted to the increase of weight in 21 patients (38.2%), but most did ... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5314557 Thu, 13 Oct 2011 04:00:00 +0100 5314557 http://www.medworm.com/index.php?rid=5314556&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01571.x This article reviews the literature regarding the cutaneous presentation of VKH. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5314556 Thu, 13 Oct 2011 04:00:00 +0100 5314556 http://www.medworm.com/index.php?rid=5314555&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01572.x We report two cases of ACC and other anomalies in newborns exposed to methimazole during pregnancy. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5314555 Thu, 13 Oct 2011 04:00:00 +0100 5314555 http://www.medworm.com/index.php?rid=5285793&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01419.x We report a case of necrolytic acral erythema in a 17‐year‐old followed by a review of the literature. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5285793 Tue, 04 Oct 2011 04:00:00 +0100 5285793 http://www.medworm.com/index.php?rid=5285792&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01422.x Abstract:  Terra firma‐forme dermatosis is an idiopathic condition characterized by acquired, dirtlike plaques despite normal hygiene. A diagnosis can be reached by removing lesions with gentle alcohol swabbing. Although Terra firma‐forme dermatosis was first described more than 20 years ago and is thought to be not uncommon in clinical practice, it has never been systematically studied. There are few publications about this condition, including no case series of more than six patients. In particular, little is known about the incidence, peak age groups, and most common locations of Terra firma‐forme dermatosis. A retrospective review was conducted to identify cases of Terra firma‐forme dermatosis in a single‐provider practice consisting of 55% pediatric and 45% adult patient... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5285792 Tue, 04 Oct 2011 04:00:00 +0100 5285792 http://www.medworm.com/index.php?rid=5285791&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01465.x We present a case of CD30+, ALK− S‐ALCL in a 7‐year‐old girl. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5285791 Tue, 04 Oct 2011 04:00:00 +0100 5285791 http://www.medworm.com/index.php?rid=5285790&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01431.x We report the unusual case of a young child who developed an idiopathic basal cell carcinoma (BCC). The patient was otherwise healthy, with no history of excessive sun or radiation exposure or any predisposing factors for nonmelanoma skin cancer. This is a rare case that exemplifies the need for pediatricians and dermatologists to be aware that BCC may occur in children, even if they have no predisposing factors. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5285790 Tue, 04 Oct 2011 04:00:00 +0100 5285790 http://www.medworm.com/index.php?rid=5285789&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01466.x Abstract:  Milia en plaque is a rare variant of miliathat occurs spontaneously on an erythematous base without identifiable causative factors. Approximately 40 cases have been recorded in the literature. Most occurred in the periauricular area, affected middle‐aged patients, and showed a predilection for women. Here, we report a case of milia en plaque on the bilateral posterior helices in a 6‐year‐old Chinese boy. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5285789 Tue, 04 Oct 2011 04:00:00 +0100 5285789 http://www.medworm.com/index.php?rid=5285788&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01467.x Abstract:  Malakoplakia is a rare, chronic disease with pleomorphic presentation. It occurs most frequently in immunocompromised patients. It is believed that this entity represents an unusual response to bacterial infection in which macrophages fail to phagocytose them properly. It involves many organs, particularly the urinary and gastrointestinal tracts. It is uncommon on the skin and less common in children. The diagnosis is usually based on histopathologic findings. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5285788 Tue, 04 Oct 2011 04:00:00 +0100 5285788 http://www.medworm.com/index.php?rid=5285787&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01488.x Abstract:  Severe forms of atopic dermatitis (AD) cause significant morbidity in vulnerable pediatric populations and necessitate treatment with systemic therapy. The existing literature concerning the treatment of severe pediatric AD with azathioprine (AZ) and mycophenolate mofetil (MM) is sparse. The purpose of this case series is to examine the use of these two drugs in the treatment of severe pediatric AD. Medical records of 28 pediatric patients with AD from the University of North Carolina at Chapel Hill pediatric dermatology clinic treated using these two drugs were analyzed for laboratory values, thiopurine methyltransferase (TPMT) levels, symptoms, infections, and other relevant data. Patients were also contacted via the telephone to ascertain outcomes and any missing data. Trea... Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5285787 Tue, 04 Oct 2011 04:00:00 +0100 5285787 http://www.medworm.com/index.php?rid=5285786&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01486.x We report a case of refractory HV successfully treated with dietary fish oil rich in ω‐3 polyunsaturated fatty acids. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5285786 Tue, 04 Oct 2011 04:00:00 +0100 5285786 http://www.medworm.com/index.php?rid=5285785&cid=s_31727_12_f&fid=31727&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1525-1470.2011.01509.x We report a 5‐year‐old Chinese boy who presented with extensive lesions consisting of disseminated pruritic vesicles and tense blisters. The diagnosis of EBA was confirmed by histopathology, immunofluorescence, and immunoblotting analysis. The disease was controlled with a combination of prednisone and dapsone. (Source: Pediatric Dermatology) Pediatric Dermatology journals http://www.medworm.com/rss/comments.php?id=5285785 Tue, 04 Oct 2011 04:00:00 +0100 5285785