MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Perfusion' source. Tue, 07 Feb 2012 03:52:37 +0100 http://www.medworm.com/index.php?rid=5658952&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22301391%26dopt%3DAbstract Conclusion. The study demonstrated that RPP is associated with MPI findings using gated SPECT imaging with dipyridamole stress. However, to confirm this preliminary result, further studies are mandatory. PMID: 22301391 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5658952 Thu, 02 Feb 2012 05:00:00 +0100 5658952 http://www.medworm.com/index.php?rid=5658951&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22301392%26dopt%3DAbstract CONCLUSION: During cardiac surgery under CPB, heparin and protamine titration with the Hepcon/HMS device could predict a lower protamine dose and lower postoperative bleeding without higher thromboembolic events, and lower perioperative red blood cell transfusion with a shorter chest closure time. PMID: 22301392 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5658951 Thu, 02 Feb 2012 05:00:00 +0100 5658951 http://www.medworm.com/index.php?rid=5621408&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22249962%26dopt%3DAbstract CONCLUSIONS: The compact portable ECMO device Cardiohelp is a highly effective method to secure vital gas exchange and to reduce further ventilator-induced lung injury in patients with acute respiratory failure. Crucial technical innovations and ease of device transport and implantation allow location-independent stabilization with consecutive inter-hospital transfer. PMID: 22249962 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5621408 Mon, 16 Jan 2012 05:00:00 +0100 5621408 http://www.medworm.com/index.php?rid=5621407&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22249963%26dopt%3DAbstract CONCLUSION: No major complication was observed during the early follow-up period in patients who underwent CAS in our clinic. Only 2 (2.5%) patients showed transient numbness and weakness and these did not lead to morbidity. In the management guide of extracranial carotid and vertebral artery diseases, CAS, in the light of recent studies, is recommended as an alternative to CEA in recommendations for revascularization. One of the important issues emphasized in this guide is the experience of centers. Very low complication rates after CAS suggested that, with suitable patient selection and an experienced team, similar results may be obtained. PMID: 22249963 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5621407 Mon, 16 Jan 2012 05:00:00 +0100 5621407 http://www.medworm.com/index.php?rid=5621406&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22249964%26dopt%3DAbstract Authors: Itoh H, Ichiba S, Ujike Y, Kasahara S, Arai S, Sano S Abstract Extracorporeal membrane oxygenation (ECMO) has emerged as an effective mechanical support following cardiac surgery with respiratory and cardiac failure. However, there are no clear indications for ECMO use after pediatric cardiac surgery. We retrospectively reviewed medical records of 76 pediatric patients [mean age, 10.8 months (0-86); mean weight, 5.16 kg (1.16-16.5)] with congenital heart disease who received ECMO following cardiac surgery between January 1997 and October 2010. Forty-five patients were treated with an aggressive ECMO approach (aggressive ECMO group, April 2005-October 2010) and 31 with a delayed ECMO approach (delayed ECMO group, January 1997-March 2005). Demographics, diagnosis, operative ... Perfusion journals http://www.medworm.com/rss/comments.php?id=5621406 Mon, 16 Jan 2012 05:00:00 +0100 5621406 http://www.medworm.com/index.php?rid=5599796&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22246229%26dopt%3DAbstract Authors: PMID: 22246229 [PubMed - in process] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5599796 Sun, 01 Jan 2012 05:00:00 +0100 5599796 http://www.medworm.com/index.php?rid=5599795&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22246230%26dopt%3DAbstract Authors: Fitzgerald DJ PMID: 22246230 [PubMed - in process] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5599795 Sun, 01 Jan 2012 05:00:00 +0100 5599795 http://www.medworm.com/index.php?rid=5599794&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22246231%26dopt%3DAbstract Authors: Walker J PMID: 22246231 [PubMed - in process] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5599794 Sun, 01 Jan 2012 05:00:00 +0100 5599794 http://www.medworm.com/index.php?rid=5599793&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22246232%26dopt%3DAbstract Authors: Griffith K PMID: 22246232 [PubMed - in process] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5599793 Sun, 01 Jan 2012 05:00:00 +0100 5599793 http://www.medworm.com/index.php?rid=5534392&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22185951%26dopt%3DAbstract Authors: Campbell J, Holland C, Richens D, Skinner H Abstract Intraoperative cell salvage of the cardiopulmonary bypass residual volume can dilute platelets and coagulation factors. This is a report of a randomised control trial of 20 patients undergoing coronary bypass surgery. Residual cardiopulmonary bypass volume was processed and transfused after surgery in the cell salvage group and the residual volume was transfused unprocessed in the control group. The coagulation profile was measured using the Rotem(®) thrombelastometry system. Mean (SD) maximum clot firmness after surgery was 52.8 (5.4) mm in the cell salvage group compared to 57.2 (5.0) mm in the control group (p=0.04). Clot formation time was prolonged after surgery by 39 (27) s in the cell saver group compared to 19 (... Perfusion journals http://www.medworm.com/rss/comments.php?id=5534392 Tue, 20 Dec 2011 05:00:00 +0100 5534392 http://www.medworm.com/index.php?rid=5513237&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22170877%26dopt%3DAbstract Authors: Andrejaitiene J, Sirvinskas E Abstract The purpose of this study was to identify the post-cardiac surgery delirium risk factors and to evaluate clinical outcomes. Data on 90 patients with postoperative delirium after cardiac surgery on cardiopulmonary bypass (CPB) were analyzed retrospectively. The patients were divided into two groups by evaluating the severity of the delirium: light and moderate delirium group (n=74) and severe delirium group (n=16). We found that the rate of early post-cardiac surgery delirium was low (4.17%). We have determined that post-cardiac surgery delirium prolonged the length of stay in the Intensive Care Unit (ICU) by (8.4 (8.6)) and the hospital stay by (23.6 (13.0)) days. The patients had higher preoperative risk scores, their age was 71.5 (8... Perfusion journals http://www.medworm.com/rss/comments.php?id=5513237 Wed, 14 Dec 2011 05:00:00 +0100 5513237 http://www.medworm.com/index.php?rid=5513239&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22143091%26dopt%3DAbstract Authors: Karapanagiotidis G, Lees N, Howlett P, Zakkar M, Sarsam M Abstract An 81-year-old woman with recurrent episodes of dizzy spells was found to have a mass in the right atrium on transthoracic echocardiography. The patient underwent successful surgery to excise the mass, which was arising from the anterior leaflet of the tricuspid valve. Histology showed a papillary fibroelastoma. Although management is still controversial when such tumours are found incidentally in asymptomatic patients, surgery may be considered, especially if the tumour is large, due to the high risk of embolism. PMID: 22143091 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5513239 Mon, 05 Dec 2011 05:00:00 +0100 5513239 http://www.medworm.com/index.php?rid=5513238&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22143092%26dopt%3DAbstract We describe a new technique to reperfuse the extremity. The ipsilateral posterior tibial artery is exposed via a small incision behind the medial malleolus. The vessel is cannulated in a retrograde fashion and connected to the arterial limb of the ECMO circuit.Thirty-six patients received a posterior tibial reperfusion cannula: average flow was 155.8 ml/min and increased over the initial 24 hours. Fifty-eight percent received the posterior tibial cannula within 6 hours of ECMO initiation and none sustained permanent lower extremity injury. Of the remaining 42%, three required amputation or developed permanent neurologic injury. Overall survival was 41%.Cannulation of the posterior tibial artery is a simple technique to reperfuse the lower extremity during VA ECMO. The cannula should be ins... Perfusion journals http://www.medworm.com/rss/comments.php?id=5513238 Mon, 05 Dec 2011 05:00:00 +0100 5513238 http://www.medworm.com/index.php?rid=5513241&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22115879%26dopt%3DAbstract This study used a simulated CPB circuit identical to that in a clinical setting to examine three different hollow-fiber membrane oxygenators without intergrated arterial filters - the Capiox RX05, the Quadrox-i neonatal, and the KIDS D100 - to determine their ability to reduce the number of GME delivered to the neonatal patient and their hemodynamic properties in response to varying flow rates, normothermic vs hypothermic conditions, and open vs closed purge line. The circuit was primed with Ringer's Lactate and then human blood with a hematocrit of 30%. Injections of 5cc bolusses of air were injected into the venous line proximal to the venous reservoir over a thirty-second interval. Six injections were done for each oxygenator at each of the eight different experimental conditions for a ... Perfusion journals http://www.medworm.com/rss/comments.php?id=5513241 Thu, 24 Nov 2011 05:00:00 +0100 5513241 http://www.medworm.com/index.php?rid=5513240&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22115880%26dopt%3DAbstract CONCLUSION: Off-pump surgery is associated with a reduction in postoperative renal injury. PMID: 22115880 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5513240 Thu, 24 Nov 2011 05:00:00 +0100 5513240 http://www.medworm.com/index.php?rid=5419682&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22049062%26dopt%3DAbstract CONCLUSION: A short interval of HCA (5 min) followed by a more extended period of ASCP (25 min) at moderate hypothermia (28°C), with a pump flow rate of 10ml/kg/min and a cerebral perfusion pressure of 50 mmHg, represents safe conditions for open arch surgery. PMID: 22049062 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5419682 Wed, 02 Nov 2011 04:00:00 +0100 5419682 http://www.medworm.com/index.php?rid=5419685&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22028284%26dopt%3DAbstract Authors: Punjabi PP PMID: 22028284 [PubMed - in process] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5419685 Tue, 01 Nov 2011 04:00:00 +0100 5419685 http://www.medworm.com/index.php?rid=5419684&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22028285%26dopt%3DAbstract Authors: Bui J PMID: 22028285 [PubMed - in process] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5419684 Tue, 01 Nov 2011 04:00:00 +0100 5419684 http://www.medworm.com/index.php?rid=5419683&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22028286%26dopt%3DAbstract Authors: Abstract The article 'Treating pulmonary hypertension post cardiopulmonary bypass in pigs: milrinone vs. sildenafil analog' by F Urdaneta, EB Lobato, T Beaver, JD Muehlschlegel, DS Kirby, C Klodell and A Sidi published in Perfusion 2008 23: 117-125, 10.1177/0267659108094739 has been retracted. PMID: 22028286 [PubMed - in process] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5419683 Tue, 01 Nov 2011 04:00:00 +0100 5419683 http://www.medworm.com/index.php?rid=5419686&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22025358%26dopt%3DAbstract Authors: Griffith KE, Jenkins E, Paugh T, Stulak J, Pagani F Abstract Right ventricular failure (RVF) following implantation of a left ventricular assist system (LVAS) is associated with high morbidity and mortality.(1-4) Numerous centers have reported short-term use of the CentriMag® Ventricular Assist System (CVAS) (Levitronix LLC, Waltham, MA) for treatment of cardiogenic shock, decompensated heart failure and right ventricular failure (RVF) following LVAS implantation.(5-9) The present report reviews the clinical course of a patient requiring long-term right ventricular support utilizing the CVAS, following a HeartMate® II LVAS (Thoratec Corp. Pleasanton, CA) implantation. Elevated cytotoxic antibody levels complicated the patient's treatment plan by precluding orthotropic he... Perfusion journals http://www.medworm.com/rss/comments.php?id=5419686 Mon, 24 Oct 2011 04:00:00 +0100 5419686 http://www.medworm.com/index.php?rid=5419687&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22020874%26dopt%3DAbstract Authors: Melchior RW, Rosenthal T, Schiavo K, Frey T, Rogers D, Patel J, Holt D PMID: 22020874 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5419687 Fri, 21 Oct 2011 04:00:00 +0100 5419687 http://www.medworm.com/index.php?rid=5344752&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22002965%26dopt%3DAbstract CONCLUSIONS: Our data conclude that there is no correlation between DEHP leaching and the inflammatory response after ECC support, but this study showed that even DEHP-free material is leaching DEHP and its toxic metabolites. PMID: 22002965 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5344752 Mon, 17 Oct 2011 04:00:00 +0100 5344752 http://www.medworm.com/index.php?rid=5344751&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22002966%26dopt%3DAbstract Authors: Walker JL, Wiersch J, Benson C, Young H, Dearmond D, Johnson S Abstract A 20-year-old male was involved in a motor vehicle accident and computed tomography revealed a completely transected right mainstem bronchus. An Emergency Department (ED) right anterior thoracotomy was necessary soon after arrival at our institution secondary to acute desaturation that was unresponsive to ventilator and chest tube management. This allowed direct intubation and ventilation of the right middle and lower lobes directly through the thoracotomy incision, which stabilized the patient for transport to the operating room. Once there, percutaneous cardiopulmonary support (CPS) was initiated to allow primary surgical repair of the transected bronchus. Post surgery, the patient was transported to... Perfusion journals http://www.medworm.com/rss/comments.php?id=5344751 Mon, 17 Oct 2011 04:00:00 +0100 5344751 http://www.medworm.com/index.php?rid=5344750&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22002967%26dopt%3DAbstract CONCLUSION: We found that off-pump coronary artery bypass grafting had less negative effects on inflammatory response and central nervous system compared to pulsatile cardiopulmonary bypass and non-pulsatile cardiopulmonary bypass techniques. PMID: 22002967 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5344750 Mon, 17 Oct 2011 04:00:00 +0100 5344750 http://www.medworm.com/index.php?rid=5344749&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22002968%26dopt%3DAbstract CONCLUSIONS: With the data available, we could not prove that starch-based colloid (HES130) had a different impact on intra-operative blood glucose than a gelatin-based colloid in adult patients receiving open heart surgery. PMID: 22002968 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5344749 Mon, 17 Oct 2011 04:00:00 +0100 5344749 http://www.medworm.com/index.php?rid=5344748&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22005885%26dopt%3DAbstract We report here Japan's first pediatric perfusion survey. It covers practices from January 2007 through December 2009. Of the 70 congenital heart centers contacted, 53 (76%) completed the survey. They reported performing 3,379 pediatric cardiopulmonary bypass (CPB) procedures in 2009, 3,408 in 2008, and 3,358 in 2007. Twenty-eight percent of all centers used CPB circuits with a priming volume between 151-200 ml. All centers used pre-bypass ultrafiltration and only 6% used retrograde autologous priming. A biomaterial-coated circuit was used by 78% of the centers, a roller pump as the arterial pump by 91%, vacuum-assisted venous drainage by 39%, dilutional ultrafiltration by 48%, and modified ultrafiltration at the end of the procedure by 30%. A regional oxygen saturation monitor was used by ... Perfusion journals http://www.medworm.com/rss/comments.php?id=5344748 Mon, 17 Oct 2011 04:00:00 +0100 5344748 http://www.medworm.com/index.php?rid=5344747&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22005886%26dopt%3DAbstract CONCLUSION: del Nido cardioplegia solution is a reasonable tool for myocardial protection during congenital heart surgery that significantly decreased the number of cardioplegic interventions and perioperative glucose values in our study groups. PMID: 22005886 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5344747 Mon, 17 Oct 2011 04:00:00 +0100 5344747 http://www.medworm.com/index.php?rid=5344746&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22005887%26dopt%3DAbstract CONCLUSIONS: The plasma level of K is reduced by 13.7% after MUF (p<0.0001). The reduction in Mg at the same period of time was not statistically significant (p<0.970). PMID: 22005887 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5344746 Mon, 17 Oct 2011 04:00:00 +0100 5344746 http://www.medworm.com/index.php?rid=5344753&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21987667%26dopt%3DAbstract CONCLUSION: In conclusion, the MECC system is a safe alternative for patients who undertake extracorporeal circulation (ECC) for CABG surgery. Lower transfusion requirements and less damage to red cells may further promote the use of MECC systems, especially in higher risk patients. PMID: 21987667 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5344753 Mon, 10 Oct 2011 04:00:00 +0100 5344753 http://www.medworm.com/index.php?rid=5344754&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21983125%26dopt%3DAbstract CONCLUSION: Compared to "miniaturised" CPB patients, the significantly higher IFNγ receptor expression on granulocytes was found in "standard" CPB patients (p<0.05) on the 1(st) postoperative day. PMID: 21983125 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5344754 Fri, 07 Oct 2011 04:00:00 +0100 5344754 http://www.medworm.com/index.php?rid=5296960&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21971319%26dopt%3DAbstract CONCLUSION: Milrinone suppresses the reduction of SjO(2) and improves the balance of cerebral oxygen supply and demand during the early rewarming period of hypothermic cardiopulmonary bypass. PMID: 21971319 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5296960 Tue, 04 Oct 2011 04:00:00 +0100 5296960 http://www.medworm.com/index.php?rid=5296959&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21971320%26dopt%3DAbstract We report two outstanding cases of prone under conditions of a veno-venous ECMO therapy which improved significantly under this position. Furthermore, we reflect critically possible risk factors and adverse events of such procedures and afford a current view from the literature. PMID: 21971320 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5296959 Tue, 04 Oct 2011 04:00:00 +0100 5296959 http://www.medworm.com/index.php?rid=5296969&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21933815%26dopt%3DAbstract "Silver lining". Perfusion. 2011 Sep;26 Suppl 1:5 Authors: Punjabi PP PMID: 21933815 [PubMed - in process] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5296969 Thu, 01 Sep 2011 04:00:00 +0100 5296969 http://www.medworm.com/index.php?rid=5296968&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21933816%26dopt%3DAbstract Authors: Kurusz M Abstract Perfusion safety has been studied and discussed extensively for decades. Many initiatives occurred through efforts of professional organizations to achieve recognition, establish accreditation and certification, promote consensus practice guidelines, and develop peer-reviewed journals as sources for dissemination of clinical information. Newer initiatives have their basis in other disciplines and include systems approach, Quality Assurance/Quality Improvement processes, error recognition, evidence-based methodologies, registries, equipment automation, simulation, and the Internet. Use of previously established resources such as written protocols, checklists, safety devices, and enhanced communication skills has persisted to the present in promoting perfus... Perfusion journals http://www.medworm.com/rss/comments.php?id=5296968 Thu, 01 Sep 2011 04:00:00 +0100 5296968 http://www.medworm.com/index.php?rid=5296967&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21933817%26dopt%3DAbstract This article gives an overview of these techniques, with their respective advantages and disadvantages. PMID: 21933817 [PubMed - in process] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5296967 Thu, 01 Sep 2011 04:00:00 +0100 5296967 http://www.medworm.com/index.php?rid=5296966&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21933818%26dopt%3DAbstract Authors: Alston R Abstract Brain damage, in the form of stroke and cognitive deficit associated with heart surgery, has long been attributed unquestioningly to cardiopulmonary bypass (CPB). The aim of this paper is to review the randomised control trials (RCT), systematic reviews and meta-analyses of studies, comparing patients who have undergone on- or off-pump coronary artery bypass grafting (CABG) surgeries that have used stroke or cognition as an outcome to determine whether CPB is associated with brain damage. Although not definitive, the evidence base to date strongly suggests that the incidence of stroke and the effect on cognition, if any, are no different whether CABG surgery is undertaken on- or off-pump. In addition and contrary to long-held beliefs, this review leads to... Perfusion journals http://www.medworm.com/rss/comments.php?id=5296966 Thu, 01 Sep 2011 04:00:00 +0100 5296966 http://www.medworm.com/index.php?rid=5296965&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21933819%26dopt%3DAbstract Authors: Elmistekawy EM, Rubens FD Abstract Deep hypothermic circulatory arrest is an essential tool in the surgeon's armamentarium. There are essentially three strategies to address cerebral ischemia during arrest periods. Early surgical case series pioneered the option of complete anoxia with deep hypothermia. Subsequent innovators introduced the concept of retrograde perfusion of the cerebral vessels through the venous system, and others have advocated the use of selective and non-selective antegrade perfusion of the cerebral arteries. Clinical studies assessing outcomes of the three approaches are compromised by small patient numbers, retrospective design and surgeon bias. In this review, the authors will briefly discuss the conceptual basis of these strategies and the literatu... Perfusion journals http://www.medworm.com/rss/comments.php?id=5296965 Thu, 01 Sep 2011 04:00:00 +0100 5296965 http://www.medworm.com/index.php?rid=5296964&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21933820%26dopt%3DAbstract Authors: Undar A, Palanzo D, Qiu F, Alkan-Bozkaya T, Akcevin A, Talor J, Baer L, Woitas K, Wise R, McCoach R, Guan Y, Haines N, Wang S, Clark JB, Myers JL Abstract This review on the benefits of pulsatile flow includes not only experimental and clinical data, but also attempts to further illuminate the major factors as to why this debate has continued during the past 55 years. Every single component of the cardiopulmonary bypass (CPB) circuitry is equally important for generating adequate quality of pulsatility, not only the pump. Therefore, translational research is a necessity to select the best components for the circuit. Generation of pulsatile flow depends on an energy gradient; precise quantification in terms of hemodynamic energy levels is, therefore, a necessity, not an opt... Perfusion journals http://www.medworm.com/rss/comments.php?id=5296964 Thu, 01 Sep 2011 04:00:00 +0100 5296964 http://www.medworm.com/index.php?rid=5296963&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21933821%26dopt%3DAbstract Authors: Harling L, Punjabi PP, Athanasiou T Abstract Recognition of the potentially deleterious effects of esxtracorporeal circulation led to off-pump coronary artery surgery (OPCAB) experiencing a surge in popularity in the initial decade after its conception. However, OPCAB has its own limitations and technical difficulties, such as coronary access, increased left ventricular size and reduced function, which may lead to the potential for suboptimal revascularization. As an alternative technique, miniaturized extracorporeal circulation (mECC) may provide a more controlled operative field in which the heart may be manipulated whilst minimizing the inflammatory, coagulopathic and haemodilutional effects of cardiopulmonary bypass. In this review, we outline the proposed benefits of ... Perfusion journals http://www.medworm.com/rss/comments.php?id=5296963 Thu, 01 Sep 2011 04:00:00 +0100 5296963 http://www.medworm.com/index.php?rid=5296961&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21933822%26dopt%3DAbstract Authors: Suleiman MS, Hancock M, Shukla R, Rajakaruna C, Angelini G Abstract Cardioplegic arrest and cardiopulmonary bypass are key triggers of myocardial injury during aortic valve surgery. Cardioplegic ischaemic arrest is associated with disruption to metabolic and ionic homeostasis in cardiomyocytes. These changes predispose the heart to reperfusion injury caused by elevated intracellular reactive oxygen species and calcium. Cardiopulmonary bypass is associated with an inflammatory response that can generate systemic oxidative stress which, in turn, provokes further damage to the heart. Techniques of myocardial protection are routinely applied to all hearts, irrespective of their pathology, although different cardiomypathies respond differently to ischaemia and reperfusion injur... Perfusion journals http://www.medworm.com/rss/comments.php?id=5296961 Thu, 01 Sep 2011 04:00:00 +0100 5296961 http://www.medworm.com/index.php?rid=5218901&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21900409%26dopt%3DAbstract Authors: Kurusz M PMID: 21900409 [PubMed - in process] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5218901 Thu, 01 Sep 2011 04:00:00 +0100 5218901 http://www.medworm.com/index.php?rid=5218900&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21900410%26dopt%3DAbstract Authors: Trew A PMID: 21900410 [PubMed - in process] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5218900 Thu, 01 Sep 2011 04:00:00 +0100 5218900 http://www.medworm.com/index.php?rid=5218899&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21900411%26dopt%3DAbstract Authors: Smith T PMID: 21900411 [PubMed - in process] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5218899 Thu, 01 Sep 2011 04:00:00 +0100 5218899 http://www.medworm.com/index.php?rid=5157309&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21859785%26dopt%3DAbstract CONCLUSION: A larger study is necessary to examine the relevance of perfusion defects to metabolic changes in affected myocytes and to global right ventricular function. PMID: 21859785 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5157309 Sun, 21 Aug 2011 23:00:00 +0100 5157309 http://www.medworm.com/index.php?rid=5157308&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21859786%26dopt%3DAbstract We present a 51-year-old man with cardiogenic shock in whom a percutaneous extracorporeal life support system (ECLS) was inserted to restore cardiopulmonary stability. After successful stabilization, a left ventricular assist device was implanted, using the ECLS without switching to a conventional cardiopulmonary bypass system to reduce its side effects. PMID: 21859786 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5157308 Sun, 21 Aug 2011 23:00:00 +0100 5157308 http://www.medworm.com/index.php?rid=5157307&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21859787%26dopt%3DAbstract CONCLUSION: The result of this first measurement seems to demonstrate that the standard technique of conducting cardiopulmonary bypass produces low muscle oxygen tension and, thus, little perfusion of skeletal muscle. The data also indicate that both high mean arterial blood pressure and high flow are necessary during CPB to ensure skeletal muscle perfusion. The investigation is continuing. PMID: 21859787 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5157307 Sun, 21 Aug 2011 23:00:00 +0100 5157307 http://www.medworm.com/index.php?rid=5157306&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21859788%26dopt%3DAbstract We present the case of a 74-year-old female who underwent complicated aortic surgery and was transfused large volumes of cell-saved blood due to post-operative bleeding, which subsequently led to coagulopathy. PMID: 21859788 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5157306 Sun, 21 Aug 2011 23:00:00 +0100 5157306 http://www.medworm.com/index.php?rid=5157305&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21859789%26dopt%3DAbstract CONCLUSION: These results confirm both the safety and efficacy of the ROCsafeRX MPC for a large variety of cardiac patients. Minimized perfusion circuits should, therefore, play a greater role in daily practice so that as many patients as possible can benefit from their advantages. PMID: 21859789 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5157305 Sun, 21 Aug 2011 23:00:00 +0100 5157305 http://www.medworm.com/index.php?rid=5157304&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21859790%26dopt%3DAbstract Authors: Mick S, Hilberath JN, Davidson MJ, Fitzgerald D Abstract A 36-year-old woman with normal renal function underwent a total arch replacement requiring 110 minutes of deep hypothermic circulatory arrest. Prior to rewarming, a pH of 7.063 with a base deficit of 10.8 was obtained. Zero-balance ultrafiltration (Z-BUF) was initiated during rewarming 7 minutes after resumption of cardiopulmonary bypass. After one hour (10L) of Z-BUF, all electrolyte and acid-base disturbances were fully corrected. Our case illustrates that Z-BUF offers a valuable option for the correction of severe electrolyte and acid-base disturbances in adults undergoing cardiac surgery. Its use should be considered in addition to the more standard pharmacologic approaches to such derangements as it offers rapi... Perfusion journals http://www.medworm.com/rss/comments.php?id=5157304 Sun, 21 Aug 2011 23:00:00 +0100 5157304 http://www.medworm.com/index.php?rid=5141316&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21844112%26dopt%3DAbstract CONCLUSIONS: This pilot study shows that non-invasive monitoring by transcranial Doppler could be a potential tool to monitor LME during cardiopulmonary bypass surgery. PMID: 21844112 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5141316 Sun, 14 Aug 2011 23:00:00 +0100 5141316 http://www.medworm.com/index.php?rid=5141315&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21844113%26dopt%3DAbstract CONCLUSIONS: Since the change in regional cerebral oxygen saturation was correlated with the change in arterial CO(2) tension during mild hypothermic CPB, NIRS might be a possible non-invasive method for monitoring of arterial CO(2) tension without incurring additional cost in this setting. PMID: 21844113 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5141315 Sun, 14 Aug 2011 23:00:00 +0100 5141315 http://www.medworm.com/index.php?rid=5141318&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21828161%26dopt%3DAbstract We report the successful use of bivalirudin for anticoagulation during cardiopulmonary bypass in a small child with HIT, using novel techniques not previously described. PMID: 21828161 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5141318 Mon, 08 Aug 2011 23:00:00 +0100 5141318 http://www.medworm.com/index.php?rid=5052552&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21752926%26dopt%3DAbstract CONCLUSION: The anti-inflammatory properties of aprotinin may be protective against postoperative arrhythmias. Aprotinin does not confer increased risks of prolonged chest tube drainage, renal dysfunction or thrombosis in patients undergoing the Fontan procedure. PMID: 21752926 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5052552 Tue, 12 Jul 2011 23:00:00 +0100 5052552 http://www.medworm.com/index.php?rid=5052553&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21742756%26dopt%3DAbstract Authors: Fluger I, Maderová K, Simek M, Hájek R, Zapletalová J, Lonsky V When cardiopulmonary bypass (CPB) is used, the blood comes into contact with foreign surfaces. To diminish this impact, various types of biocompatibly coated surfaces have been developed. The study assessed the effects of heparin-coated CPB systems on the level and function of fibrinogen as measured by thromboelastography (TEG), as compared with non-coated systems. No statistically significant differences between both groups were revealed by comparing paired data. In our study, heparin-coated CPB circuits had no significant effect on either fibrinogen level or its function. PMID: 21742756 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=5052553 Thu, 07 Jul 2011 23:00:00 +0100 5052553 http://www.medworm.com/index.php?rid=4960518&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21665910%26dopt%3DAbstract CONCLUSION: The study found that, among the various factors, job demands were the most likely culprit contributing to burnout. Stress level and conflict, in particular, had the strongest association to burnout. PMID: 21665910 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4960518 Sun, 12 Jun 2011 23:00:00 +0100 4960518 http://www.medworm.com/index.php?rid=4960517&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21665911%26dopt%3DAbstract Authors: Scrascia G, Guida P, Rotunno C, De Palo M, Mastro F, Pignatelli A, de Luca Tupputi Schinosa L, Paparella D The ideal cardioplegic strategy in thoracic aorta operations requiring long cardiopulmonary bypass and cross-clamp time has not been established. Suboptimal myocardial protection may lead to myocardial damage and possible post-operative complications. We evaluate post-operative cardiac Troponin I (cTnI) release, low cardiac output syndrome (LCOS) and mortality, using a cold crystalloid single-dose intracellular or cold blood multidose cardioplegia in 112 elective or emergent thoracic aorta operation patients. Fifty-four patients (HTK group) received Custodiol® cardioplegic solution and 58 received cold blood cardioplegia (CB group). Cross-clamp time, cardiopulmonary bypa... Perfusion journals http://www.medworm.com/rss/comments.php?id=4960517 Sun, 12 Jun 2011 23:00:00 +0100 4960517 http://www.medworm.com/index.php?rid=4960516&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21665912%26dopt%3DAbstract CONCLUSIONS: Patient's age could be a moderate indicator of AT activity drop and low preoperative AT activity could be a sign of reduced anticoagulant efficacy of heparin during CPB. PMID: 21665912 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4960516 Sun, 12 Jun 2011 23:00:00 +0100 4960516 http://www.medworm.com/index.php?rid=4912095&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21628339%26dopt%3DAbstract CONCLUSION: Our data suggest that off-pump CABG patients have the same late mortality, MACEs, and graft patency rates as conventional cardioplegic cardiac arrest CABG patients. In our opinion, urgent or emergency CABG for patients with STEMI can be done either way. PMID: 21628339 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4912095 Mon, 30 May 2011 23:00:00 +0100 4912095 http://www.medworm.com/index.php?rid=4912094&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21628340%26dopt%3DAbstract Authors: Karabay C, Gecmen C, Aung S, Guler A, Candan O, Batgerel U, Kalayci A, Kirma C Cardiovascular hypersensitivity is a rare and well-documented side-effect of 5-FU (5-fluorouracil). Besides the common complications such as angina pectoris and myocardial infarction, it can also cause cardiogenic shock, and supraventricular and ventricular arrhythmias. Studies have reported that FU-induced angina most commonly occurred due to vasospasm. In our case, 9 hours after stopping the infusion of 5-FU, the patients developed symptoms and electrocardiographic (ECG) findings consistent with acute myocardial infarction. We intend to share this rare case and discuss whether this late complication after 5-FU infusion is an FU-induced vasospasm or rather an allergic reaction leading to Kounis syn... Perfusion journals http://www.medworm.com/rss/comments.php?id=4912094 Mon, 30 May 2011 23:00:00 +0100 4912094 http://www.medworm.com/index.php?rid=4912096&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21613331%26dopt%3DAbstract Authors: Sistino JJ, Michaud NM, Sievert AN, Shackelford AG The new Perfusion Simulation Center at the Medical University of South Carolina provides a new level of high fidelity simulation training for perfusion students. A key component is the Orpheus Perfusion Simulator which is a computer-driven simulator integrated with the mechanical connections of the heart-lung machine to allow for real time operative procedures and perfusion incidents. Due to the ability to consistently reproduce cardiac surgical scenarios, it is possible to develop both basic perfusion skills as well as advanced emergency skills more effectively than with animal models. The purpose of this paper is to provide details about advanced simulation for perfusionists and to illustrate how simulation can be used to pr... Perfusion journals http://www.medworm.com/rss/comments.php?id=4912096 Tue, 24 May 2011 23:00:00 +0100 4912096 http://www.medworm.com/index.php?rid=4912097&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21610182%26dopt%3DAbstract Authors: Lindroos AC, Schramko AA, Niiya T, Suojaranta-Ylinen RT, Niemi TT Our objective was to investigate the in vitro effects of a totally balanced fluid concept on whole blood coagulation. Venous blood from 12 healthy volunteers was diluted by 20% and 40% with a combination of an equal amount of colloid (balanced or unbalanced 6% HES 130/0.4, or 4% gelatin) and crystalloid (balanced or unbalanced Ringer's acetate). Blood samples were analyzed with rotational thromboelastometry (ROTEMM(®)). The initiation of coagulation was delayed in all dilutions except for the 20 vol% gelatin-dilution. In the extrinsic activation test, maximum clot firmness was decreased and clot formation time prolonged after 40 vol% hemodilution with a balanced Ringer's/unbalanced HES combination, more than in... Perfusion journals http://www.medworm.com/rss/comments.php?id=4912097 Mon, 23 May 2011 23:00:00 +0100 4912097 http://www.medworm.com/index.php?rid=4863146&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21558302%26dopt%3DAbstract Authors: Lentini S, Recupero A Persistent left superior vena cava (PLSVC) represents the most frequent congenital malformation of the thoracic venous drainage system. In adults referred to surgery for an acquired cardiac disease, abnormal venous drainage may be missed if not carefully researched. Discovering a previously undiagnosed PLSVC during cardiopulmonary bypass (CPB) may present some inconvenience for both the perfusionist and the surgeon, especially during a minimally invasive approach. The authors believe PLSVC probably may represent an under-reported condition. A careful screening of patients undergoing cardiac surgery may prove helpful. In particular, a complete echocardiographic study may help to better diagnose this condition before surgery. Different signs may raise the s... Perfusion journals http://www.medworm.com/rss/comments.php?id=4863146 Wed, 18 May 2011 23:00:00 +0100 4863146 http://www.medworm.com/index.php?rid=4863142&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21593081%26dopt%3DAbstract Authors: Smith T, Darling E, Searles B Cell phone use in the U.S. has increased dramatically over the past decade and text messaging among adults is now mainstream. In professions such as perfusion, where clinical vigilance is essential to patient care, the potential distraction of cell phones may be especially problematic. However, the extent of this as an issue is currently unknown. Therefore, the purpose of this study was to (1) determine the frequency of cell phone use in the perfusion community, and (2) to identify concerns and opinions among perfusionists regarding cell phone use. In October 2010, a link to a 19-question survey (surveymonkey.com) was posted on the AmSECT (PerfList) and Perfusion.com (PerfMail) forums. There were 439 respondents. Demographic distribution is as fol... Perfusion journals http://www.medworm.com/rss/comments.php?id=4863142 Tue, 17 May 2011 23:00:00 +0100 4863142 http://www.medworm.com/index.php?rid=4863141&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21593082%26dopt%3DAbstract Authors: Durandy Y, Rubatti M, Couturier R As a result of improvements in early outcomes, long-term neurologicalal outcomes are becoming a major issue in pediatriccardiac surgery. The mechanisms of brain injury are numerous, but a vast majority of injuries are impervious to therapy andonly a few are modifiable. The quality of perfusion during cardiac surgery is a modifiable factor and cerebral monitoringduring bypass is the way to assess the quality of intra-operative cerebral perfusion. Near infrared spectroscopy (NIRS),as a diagnostic tool, has gained in popularity within the perfusion community. However, NIRS is becoming the standardof care before its scientific validation. This manuscript relates four clinical cases, demonstrating the limitations of NIRSmonitoring during pediatric ... Perfusion journals http://www.medworm.com/rss/comments.php?id=4863141 Tue, 17 May 2011 23:00:00 +0100 4863141 http://www.medworm.com/index.php?rid=4863140&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21593083%26dopt%3DAbstract CONCLUSIONS: Contemporary management of adult cardiac surgery under CPB still involves induction of mild to moderatesystemic hypothermia. Significant practice variation exists across the country with respect to target temperatures forcooling and rewarming, as well as the site for temperature monitoring. This probably reflects the lack of definitive evidence.There is a need for well-conducted clinical trials to provide more robust evidence regarding temperature management. PMID: 21593083 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4863140 Tue, 17 May 2011 23:00:00 +0100 4863140 http://www.medworm.com/index.php?rid=4863139&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21593084%26dopt%3DAbstract Authors: Blokker-Veldhuis MJ, Rutten P, De Hert S Volatile anaesthetic agents are widely used for maintenance of anaesthesia in all kinds of surgical procedures. Despitethe implementation of measures such as adequate ventilation of the operating room and the use of efficient scavengingsystems, concern remains about the risks for occupational exposure, especially in situations associated with an increasedrisk of anaesthetic gas waste, such as with the use of volatile anaesthetic agents on cardiopulmonary bypass. The present contribution reports the results of a preliminary safety assessment involving measurements of sevoflurane concentrations in the ambient air of a cardiac surgery operating room. In 22 cardiac surgical procedures with cardiopulmonary bypass (11 with open and 11 with cl... Perfusion journals http://www.medworm.com/rss/comments.php?id=4863139 Tue, 17 May 2011 23:00:00 +0100 4863139 http://www.medworm.com/index.php?rid=4863138&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21593085%26dopt%3DAbstract In conclusion, retrograde autologous priming, reducing the prime volume of the cardiopulmonary bypass system, causes less haemodilution and reduces intraoperative transfusion of packed red blood cells. PMID: 21593085 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4863138 Tue, 17 May 2011 23:00:00 +0100 4863138 http://www.medworm.com/index.php?rid=4863137&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21593086%26dopt%3DAbstract CONCLUSION: These data showed that redistributionand reverse redistribution of 99mTc-sestamibi post thrombolytic therapy can be used as a marker of viability to predictthe recovery of segmental wall motion abnormality (stunning), as well as the improvement of segmental perfusion uptake.This study also demonstrates that the resting 99mTc-sestamibi SPECT can be used for an approximate assessment of LVfunction status and can predict the recovery of jeopardized myocardium function after thrombolytic therapy. PMID: 21593086 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4863137 Tue, 17 May 2011 23:00:00 +0100 4863137 http://www.medworm.com/index.php?rid=4863136&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21593087%26dopt%3DAbstract Authors: McRobb C, Walczak R, Lawson S, Lodge A, Lockhart E, Bandarenko N, Ing R A 4.3 kg, three-month-old patient, diagnosed with a perimembranous ventricular septal defect, presented for cardiac surgery. Upon initiation of cardiopulmonary bypass (CPB), the patient developed carboxyhemoglobinemia (11.1%). Potential sources for the unexpected acquired carboxyhemoglobinemia were sought quickly. Testing of residual blood from the unit of packed red blood cells (PRBCs) used to prime the CPB circuit revealed a carboxyhemoglobin (COHb) of 15.1 %. A decrease in cerebral oximetry (rSO(2)) on CPB was initially felt to be a result of the elevated COHb levels. When ventilation of the oxygenator with 100% oxygen (O(2)) failed to decrease COHb levels, a partial exchange transfusion was performed w... Perfusion journals http://www.medworm.com/rss/comments.php?id=4863136 Tue, 17 May 2011 23:00:00 +0100 4863136 http://www.medworm.com/index.php?rid=4863145&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21565974%26dopt%3DAbstract In this study, five cohorts of healthy subjects were examined by ROTEM upon activation of the extrinsic or intrinsic pathway of coagulation, or recalcification alone. The cohorts comprised male subjects below (1) and above (2) 45 years of age, female subjects below 45 years of age with (3) or without (4) oral contraception, and female subjects above 45 years (5) without hormone replacement therapy. A significant influence of gender, age, and oral contraception on parameters determined by ROTEM was observed. Thus, adjustment for age, gender, and oral contraception is required when ROTEM is used to screen for distinct abnormalities of haemostasis. PMID: 21565974 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4863145 Wed, 11 May 2011 23:00:00 +0100 4863145 http://www.medworm.com/index.php?rid=4863144&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21565975%26dopt%3DAbstract Authors: Trew A, Searles B, Smith T, Darling EM Due to the emergent unpredictable nature of cardiac surgery, perfusionists, potentially, are susceptible to extended work hours and acute sleep deprivation. While fatigue among other healthcare clinicians has been studied, there has been no research on this topic specifically in the perfusion community. Therefore, the purpose of this study was to: (1) collect preliminary data on the prevalence of fatigue in perfusion and (2) identify if there were concerns regarding fatigue, performance and perfusion safety. In May 2010, a link to a 50-question survey (surveymonkey.com) was posted on Perflist and Perfmail. The survey was closed in July 2010. There were 445 respondents and data were analyzed and expressed as a response percent. Participant... Perfusion journals http://www.medworm.com/rss/comments.php?id=4863144 Wed, 11 May 2011 23:00:00 +0100 4863144 http://www.medworm.com/index.php?rid=4863143&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21565976%26dopt%3DAbstract Authors: Kaul P, George R, Paniagua R, Petsa A, Congiu S An innominate truncal dissection and rupture into the right pleural cavity with massive hemothorax is the initial presentation in this 66-year-old lady with type A dissection of the aorta complicated by right coronary ostial avulsion and inferior STEMI. She underwent supracoronary interposition graft replacement of the ascending aorta and hemiarch, interposition graft replacement of the innominate trunk and saphenous vein bypass grafting of the right coronary artery successfully. Innominate truncal rupture following aortic dissection is practically unknown and has not been described before in the absence of aortic rupture. Innominate truncal rupture secondary to other pathologies presents with supraaortic and mediastinal hematoma... Perfusion journals http://www.medworm.com/rss/comments.php?id=4863143 Wed, 11 May 2011 23:00:00 +0100 4863143 http://www.medworm.com/index.php?rid=4863150&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21558298%26dopt%3DAbstract We describe the first successful application of a newly developed, compact and easily portable ECMO device in a patientwith severe ARDS due to influenza A (H1N1). Support with the miniaturized ECMO resulted in immediate improvementof gas exchange and a highly protective ventilation. Inspiratory pressure was decreased from 40 to 29 cmH(2)O and tidalvolume per kilogram of predicted bodyweight could be reduced from 6.5 to 3.3 mL. Small and efficient heart-lung assist systems will become a tool of growing importance in intensive care medicine, bothfor profound respiratory and cardiac failure in the future. The reduced weight and compact design of the device greatlyfacilitates transport and handling of unstable patients on ECMO. PMID: 21558298 [PubMed - as supplied by publisher] (Source: Pe... Perfusion journals http://www.medworm.com/rss/comments.php?id=4863150 Mon, 09 May 2011 23:00:00 +0100 4863150 http://www.medworm.com/index.php?rid=4863149&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21558299%26dopt%3DAbstract CONCLUSION: The range of the ACT values tends to diminish over time and, consequently, the reliability of the resultsincreases. However, the difference is small and has little or no clinical relevance. Giving time for the circulation todistribute the heparin in the bloodstream, we recommend measuring the ACT two min after heparin administration. PMID: 21558299 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4863149 Mon, 09 May 2011 23:00:00 +0100 4863149 http://www.medworm.com/index.php?rid=4863148&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21558300%26dopt%3DAbstract In conclusion, SvO(2) and O(2)ER are better than the hemoglobin value for guiding the decision-making process of red blood cell transfusions to correct hemodilutional anemia during CPB. PMID: 21558300 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4863148 Mon, 09 May 2011 23:00:00 +0100 4863148 http://www.medworm.com/index.php?rid=4863147&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21558301%26dopt%3DAbstract Authors: Høgetveit JO, Saatvedt K, Norum H, Kristiansen F, Elvebakk O, Dahle G, Geiran OR Central venous catheters are mandatory during every major procedure involving extracorporeal circulation. Air emboli potentially could enter the circulation through this device when negative pressure is applied in the venous cannula. The following experimental study was initiated by a fatal massive air embolus during a vascular procedure involving cardiopulmonary bypass. An experimental setup was established, simulating a real scenario. The experiment was performed with a 40% glycerol/water mixture which exhibits properties and fluid dynamics close to blood. A heart-lung machine provided circulation of the fluid. The flow was adjusted according to the gravitational status. A triple-lumen central ... Perfusion journals http://www.medworm.com/rss/comments.php?id=4863147 Mon, 09 May 2011 23:00:00 +0100 4863147 http://www.medworm.com/index.php?rid=4863151&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21558147%26dopt%3DAbstract CONCLUSIONS: The results show the difference in flow ranges and pressure drops of seven combinations of arterial and venous cannulae. It also suggests that the arterial cannula, not the venous cannula, has greater impact on the flow rate when a centrifugal pump is used in a neonatal ECLS circuit. The results of this study have been translated to further advancing the clinical practice in our institution. PMID: 21558147 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4863151 Sun, 08 May 2011 23:00:00 +0100 4863151 http://www.medworm.com/index.php?rid=4755435&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21490079%26dopt%3DAbstract Authors: Rubens FD PMID: 21490079 [PubMed - in process] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4755435 Wed, 27 Apr 2011 17:45:38 +0100 4755435 http://www.medworm.com/index.php?rid=4755434&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21490080%26dopt%3DAbstract Authors: Xin Duan , Bingyang Ji , Kun Yu , Feilong Hei , Jinping Liu , Cun Long It is well documented that transient acidosis during reperfusion is protective. The aim of this study was to evaluate the cardioprotection of acidic buffer or plus cyclosporine A in isolated rat hearts after cardioplegic arrest. PMID: 21490080 [PubMed - in process] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4755434 Wed, 27 Apr 2011 17:45:20 +0100 4755434 http://www.medworm.com/index.php?rid=4755433&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21508085%26dopt%3DAbstract CONCLUSION: Our data confirmed that patients with a normal 99mTc-Sestamibi myocardial SPECT are associated with a very low incidence of cardiovascular events. PMID: 21508085 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4755433 Tue, 19 Apr 2011 23:00:00 +0100 4755433 http://www.medworm.com/index.php?rid=4643224&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21406485%26dopt%3DAbstract CONCLUSION: The Xtra is a device which will lead the evolution of 'next generation' cell saver technology. The user interface and data management system provide export options and the ability to record the level of data required for good EPDM. This is essential to 'future proof' cell salvage technology. The manufacturer's integrated protocol achieved a higher end product haematocrit than our perfusion team's best practice. The design of the Xtra is contemporary, but the DMS equips this cell saver for the new era that faces both Perfusion and Cardiac Surgery. PMID: 21406485 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4643224 Tue, 15 Mar 2011 00:00:00 +0100 4643224 http://www.medworm.com/index.php?rid=4643223&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21427139%26dopt%3DAbstract Authors: Punjabi PP PMID: 21427139 [PubMed - in process] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4643223 Tue, 01 Mar 2011 00:00:00 +0100 4643223 http://www.medworm.com/index.php?rid=4581597&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21357633%26dopt%3DAbstract Authors: Vasavada R, Qiu F, Undar A Extracorporeal life support (ECLS) offers lifesaving mechanical circulatory support for patients afflicted with respiratory and/or cardiac failure. Neonatal respiratory patients have higher survival rates compared to pediatric patients, while, for cardiac cases, pediatric patients are more likely to survive. The indications for ECLS have been expanded due to the improved technology and favorable outcomes. However, the rate of mortality and morbidity for ECLS patients remains significant. Mechanical complications still comprise a large percentage of ECLS complications, leaving definite room for improvement in ECLS circuit technology in the future. As a pre-clinical evaluating tool, translational research will provide more useful information for the se... Perfusion journals http://www.medworm.com/rss/comments.php?id=4581597 Mon, 28 Feb 2011 00:00:00 +0100 4581597 http://www.medworm.com/index.php?rid=4527525&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21339244%26dopt%3DAbstract CONCLUSION: Allogenic Tx amplifies the CPB-related inflammatory response. It is feasible to do congenital procedures safely without Tx for patients weighing >10 kg by using combined blood management strategies. PMID: 21339244 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4527525 Mon, 21 Feb 2011 00:00:00 +0100 4527525 http://www.medworm.com/index.php?rid=4527524&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21339245%26dopt%3DAbstract CONCLUSIONS: We demonstrated that cerebral oximetry decreases with the loss of pulsatile flow regardless of the mean arterial pressure and, furthermore, is not directly related to the haematocrit value in patients with reduced pulmonary blood flow. PMID: 21339245 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4527524 Mon, 21 Feb 2011 00:00:00 +0100 4527524 http://www.medworm.com/index.php?rid=4527523&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21339246%26dopt%3DAbstract CONCLUSION: The modified self-expanding cannula exhibited superior distal arterial flow compared to the routinely used rectilinear shunt system. This has a potential to reduce ischemic events of the inferior extremity in prolonged perfusion. PMID: 21339246 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4527523 Mon, 21 Feb 2011 00:00:00 +0100 4527523 http://www.medworm.com/index.php?rid=4472793&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21310770%26dopt%3DAbstract CONCLUSION: These findings suggested that acidic buffer or plus cyclosporine A post-conditioning prevented apoptosis-related mitochondrial permeabilization and provided the myocardial protection after cardioplegic arrest. PMID: 21310770 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4472793 Thu, 10 Feb 2011 00:00:00 +0100 4472793 http://www.medworm.com/index.php?rid=4472794&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21282298%26dopt%3DAbstract CONCLUSION: During different states of shunt opening, varying degrees of blood flow were diverted away from the arterial line. Shunting of blood flow may, therefore, result in hypoperfusion in the patient. PMID: 21282298 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4472794 Mon, 31 Jan 2011 00:00:00 +0100 4472794 http://www.medworm.com/index.php?rid=4406234&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21247984%26dopt%3DAbstract Authors: Mijovski G, Colah S, Sharples L, Wheaton E, Martinez G, Klein AA Cardiopulmonary bypass (CPB) exposes blood to artificial surfaces, which induces a systemic inflammatory activation. This may contribute to hypotension during CPB. A perceived difference between two membrane oxygenators was noted. Data were collected on 222 consecutive patients; four were excluded from the analysis due to having emergency operations. One hundred and twelve (51%) patients received the Apex oxygenator whilst 106 (49%) received the Quadrox. There was no difference between the two groups in the primary outcome; 90/112 patients (80%) in the Apex group and 77/106 (73%) in the Quadrox group (p=0.18, OR: 0.65; 95% CI: 0.34, 1.22) received meteraminol due to marked hypotension during CPB. There was also n... Perfusion journals http://www.medworm.com/rss/comments.php?id=4406234 Wed, 19 Jan 2011 00:00:00 +0100 4406234 http://www.medworm.com/index.php?rid=4406233&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21247985%26dopt%3DAbstract CONCLUSIONS: Both the Quadrox-iD Pediatric and HILITE 2400LT PMP membrane oxygenators are suitable for pediatric ECLS therapy under both non-pulsatile and pulsatile perfusion. An optimized combination of flow rate and MAP should be achieved in order to deliver the maximal pulsatile energy in the extracorporeal circuit. PMID: 21247985 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4406233 Wed, 19 Jan 2011 00:00:00 +0100 4406233 http://www.medworm.com/index.php?rid=4406232&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21247986%26dopt%3DAbstract We describe a transaortic repair of the intimal tear in the descending aorta with supracoronary interposition graft replacement of the ascending aorta and hemiarch with excellent clinical and radiological result. We also review the diagnostic and therapeutic approaches to this incompletely understood lethal disease. PMID: 21247986 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4406232 Wed, 19 Jan 2011 00:00:00 +0100 4406232 http://www.medworm.com/index.php?rid=4406231&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21247987%26dopt%3DAbstract Authors: Karabay CY, Aung SM, Tanboga IH, Kalayci A, Kocabay G, Güler A, Candan O, Kirma C It is well-known that collateral circulation is important in preserving ventricular functions, especially in coronary artery disease with total occlusion. The conus branch is distinct in having notable capacity of angiogenesis and arteriogenesis. We intend to emphasize the clinical importance of the conus branch by presenting two cases in which it supplied the distal regions of total occlusion. PMID: 21247987 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4406231 Wed, 19 Jan 2011 00:00:00 +0100 4406231 http://www.medworm.com/index.php?rid=4406235&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21242193%26dopt%3DAbstract CONCLUSION: The OPBH method seems to be safe, secure and effective in this population of very high-risk patients, reducing early complications and multi-organ failure. OPBH surgery, combining MECC without aortic cross-clamping, makes it possible to perform complete revascularization and is an interesting alternative for CABG in high-risk patients. PMID: 21242193 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4406235 Mon, 17 Jan 2011 00:00:00 +0100 4406235 http://www.medworm.com/index.php?rid=4406236&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21233151%26dopt%3DAbstract CONCLUSIONS: The select 3D cannula design reduces the sandblasting effect of the perfusion jet and, also, may direct emboli from the heart and cardiopulmonary bypass equipment away from the cerebral circulation. PMID: 21233151 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4406236 Thu, 13 Jan 2011 00:00:00 +0100 4406236 http://www.medworm.com/index.php?rid=4406239&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21227981%26dopt%3DAbstract Authors: Clements A, Jindal S, Morris C, Ikomi A, Srivastava G, Mulholland J It is important that our speciality continues to push its boundaries. Our perfusion team has invested time lecturing to non-cardiac specialties about perfusion-led technology. This resulted in working closely with the obstetrics team to treat a pregnant patient with the bleeding disorder Gray Platelet Syndrome. In the first instance, we used our Thromboelastograph (TEG) platelet mapping programme to assess the patient. These results agreed with the platelet aggregation tests, showing a degree of platelet inhibition, but it was the overall clotting profile (basic thrombelastograph), showing a borderline hyper-coagulable state, that was of most interest and commonly seen in pregnancy. We believe a TEG result wit... Perfusion journals http://www.medworm.com/rss/comments.php?id=4406239 Wed, 12 Jan 2011 00:00:00 +0100 4406239 http://www.medworm.com/index.php?rid=4406238&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21227982%26dopt%3DAbstract Authors: Khan S, Vasavada R, Qiu F, Kunselman A, Undar A Emerging technologies and practices for pediatric and neonatal extracorporeal life support (ECLS) are promising. This experiment sought to compare the Medtronic 0800 silicon rubber membrane oxygenator to the Quadrox-iD Pediatric oxygenator in the conventional roller pump circuit, as well as comparing the conventional circuit to an alternative circuit. Three circuits were set up in the experiment. Two conventional roller pump circuits were used to compare the two oxygenators and an alternative circuit consisting of the Quadrox-iD Pediatric oxygenator and Maquet Rotaflow centrifugal pump system was used to identify differences between circuits. All three circuits were primed with Lactated Ringers' solution and human blood, with an ... Perfusion journals http://www.medworm.com/rss/comments.php?id=4406238 Wed, 12 Jan 2011 00:00:00 +0100 4406238 http://www.medworm.com/index.php?rid=4406237&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21227983%26dopt%3DAbstract Authors: Clark JB, Guan Y, McCoach R, Kunselman AR, Myers JL, Undar A During extracorporeal life support with centrifugal blood pumps, retrograde pump flow may occur when the pump revolutions decrease below a critical value determined by the circuit resistance and the characteristics of the pump. We created a laboratory model to evaluate the occurrence of retrograde flow in each of three centrifugal blood pumps: the Rotaflow, the CentriMag, and the Bio-Medicus BP-50. At simulated patient pressures of 60, 80, and 100 mmHg, each pump was evaluated at speeds from 1000 to 2200 rpm and flow rates were measured. Retrograde flow occurred at low revolution speeds in all three centrifugal pumps. The Bio-Medicus pump was the least likely to demonstrate retrograde flow at low speeds, followed by ... Perfusion journals http://www.medworm.com/rss/comments.php?id=4406237 Wed, 12 Jan 2011 00:00:00 +0100 4406237 http://www.medworm.com/index.php?rid=4339742&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21177726%26dopt%3DAbstract Authors: Toomasian JM, Bartlett RH PMID: 21177726 [PubMed - in process] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4339742 Sat, 01 Jan 2011 00:00:00 +0100 4339742 http://www.medworm.com/index.php?rid=4339746&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21177722%26dopt%3DAbstract CONCLUSIONS: Ex vivo rotation thromboelastometry did not reveal the expected preservation of coagulation parameters, in particular the fibrin part of clot formation, by a balanced HES priming solution. PMID: 21177722 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4339746 Wed, 22 Dec 2010 00:00:00 +0100 4339746 http://www.medworm.com/index.php?rid=4339745&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21177723%26dopt%3DAbstract CONCLUSION: Patients receiving RSMB were less transfused with allogenic blood and had less postoperative drainage, while the frequency of observed postoperative complications was not different from patients who did not receive RSMB. PMID: 21177723 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4339745 Wed, 22 Dec 2010 00:00:00 +0100 4339745 http://www.medworm.com/index.php?rid=4339744&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21177724%26dopt%3DAbstract In conclusion, PMEA- and Phisio-coated circuits displayed similar biocompatibility with respect to inflammatory and haemostatic responses during and after open-heart surgery. PMID: 21177724 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4339744 Wed, 22 Dec 2010 00:00:00 +0100 4339744 http://www.medworm.com/index.php?rid=4339743&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21177725%26dopt%3DAbstract Authors: Raivio PM, Lassila R, Kuitunen AH, Eriksson H, Suojaranta-Ylinen RT, Petäjä J In a previous study, preoperative levels of activated protein C (APC) were associated with unfavorable postoperative hemodynamics after coronary artery bypass grafting (CABG). Protein C is activated by thrombin. Protein S, the co-factor of activated protein C, has activated protein C-independent anticoagulant activity and cytoprotective effects. Therefore, the objective of this study was to test whether preoperative, baseline levels of either thrombin or protein S were associated with hemodynamic performance or markers of myocardial damage after CABG. One hundred patients undergoing elective on-pump CABG were prospectively studied. Prothrombin fragment F1+2 (a marker of thrombin generation) and fre... Perfusion journals http://www.medworm.com/rss/comments.php?id=4339743 Wed, 22 Dec 2010 00:00:00 +0100 4339743 http://www.medworm.com/index.php?rid=4339750&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21173035%26dopt%3DAbstract We report a case of reduced cerebral oxygenation which had the possibility of leading to an adverse outcome if it had not been detected by the routine use of cerebral oximetry. This case study illustrates that an inadvertent re-adjustment of a single-stage venous cannula within the superior vena cava resulted only in the cerebral oximetry device alerting to a potential problem. All other monitoring devices remained within standard operating parameters, with no deviation throughout the duration of the incident. PMID: 21173035 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4339750 Mon, 20 Dec 2010 00:00:00 +0100 4339750 http://www.medworm.com/index.php?rid=4339749&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21173036%26dopt%3DAbstract Authors: Baufreton C, Pinaud F, Corbeau JJ, Chevailler A, Jolivot D, Ter Minassian A, Henrion D, De Brux JL The role of complement activation on the cerebral vasculature after cardiopulmonary bypass (CPB) is unclear. The goal of the study was to assess whether heparin-coated CPB reduces complement activation, and influences cerebral blood flow velocities (CBFV). Twenty-four patients undergoing coronary surgery were randomly allocated to non-coated (NC-group) or heparin-coated (HC-group) CPB. Complement activation was assessed by measuring sC5b-9. Transcranial Doppler (TCD) was performed on middle cerebral arteries before and after CPB. Systolic (SV), diastolic (DV) and mean (MV) CBFV were measured. Significant increase of sC5b-9 (p=0.003) was observed in the NC-group and CBFV increased... Perfusion journals http://www.medworm.com/rss/comments.php?id=4339749 Mon, 20 Dec 2010 00:00:00 +0100 4339749 http://www.medworm.com/index.php?rid=4339748&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21173037%26dopt%3DAbstract Authors: Charumathi D, Vaijyanath P, Sekhar L, Kothurahu Mammen C A strategy employing moderate hypothermia for replacement of the aortic arch is proposed to avoid the complications of profound hypothermic circulatory arrest. Two patients underwent complete replacement of the aortic arch using three pumps (Figure 1a - one to perfuse the brain, one for the thoracoabdominal aorta and the third for the heart). There were no complications and the patients were extubated uneventfully. The method preserves autoregulation of cerebral blood flow without high vascular resistances. PMID: 21173037 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4339748 Mon, 20 Dec 2010 00:00:00 +0100 4339748 http://www.medworm.com/index.php?rid=4339747&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21173038%26dopt%3DAbstract Authors: Qiu F, Talor J, Undar A PMID: 21173038 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4339747 Mon, 20 Dec 2010 00:00:00 +0100 4339747 http://www.medworm.com/index.php?rid=4186503&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21078768%26dopt%3DAbstract CONCLUSION: In contrast to adult critically ill patients, data from the present study did not prove that hyperglycemia was detrimental to infants receiving open-heart surgery with CPB. The existing literature and findings of our present study warranted future clinical studies of strict glycemic control in critically ill children, considering a more permissive glycemic range as a desirable target. PMID: 21078768 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4186503 Mon, 15 Nov 2010 00:00:00 +0100 4186503 http://www.medworm.com/index.php?rid=4186502&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21078769%26dopt%3DAbstract Authors: Harilall Y, Adam JK, Biccard BM, Reddi A We compared simultaneous regional cerebral oxygen saturation and central venous oxygen saturation at different time periods in 20 adult patients (median age, 57.9; range, 35 to 76 years) undergoing off-pump coronary artery bypass (OPCAB) graft surgery (n = 20). Mean arterial pressure (MAP), partial pressure of carbon dioxide (PcvCO(2)), heart rate, haematocrit (Hct), lactate and patient oxygen saturation (SpO(2)) were also recorded as a secondary analysis to determine independent predictors of cerebral desaturation and interactions between predictors. The cross-sectional analysis performed at each time point showed several significant moderate to strong positive correlations between central venous oxygen saturation and both right and le... Perfusion journals http://www.medworm.com/rss/comments.php?id=4186502 Mon, 15 Nov 2010 00:00:00 +0100 4186502 http://www.medworm.com/index.php?rid=4186501&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21078770%26dopt%3DAbstract CONCLUSION: uPAR expression on granulocytes and monocytes is significantly modulated by cardiac surgery. PMID: 21078770 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4186501 Mon, 15 Nov 2010 00:00:00 +0100 4186501 http://www.medworm.com/index.php?rid=4186500&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21078771%26dopt%3DAbstract CONCLUSION: This study's significant finding was that asymptomatic CAD is common in SLE patients, even in those thought to be low risk for CAD and in the absence of cardiac symptoms. PMID: 21078771 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4186500 Mon, 15 Nov 2010 00:00:00 +0100 4186500 http://www.medworm.com/index.php?rid=4154165&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21057061%26dopt%3DAbstract CONCLUSION: Monitoring of anti-Xa UFH and AT proved effective for measuring anticoagulation and detecting inconsistencies in other anticoagulation parameters, leading to steady levels of heparin without further complications. PMID: 21057061 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4154165 Fri, 05 Nov 2010 00:00:00 +0100 4154165 http://www.medworm.com/index.php?rid=4088582&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20965955%26dopt%3DAbstract Discussion: Only oxygenated perfusion could restore ATP in organs with warm ischemia. Initial cold static storage seems deleterious to organs having suffered from warm ischemia. Oxygenated perfusion must be introduced immediately after kidney removal from non heart-beating donors. In organs without warm ischemia, any kind of preservation is equivalent. PMID: 20965955 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4088582 Wed, 20 Oct 2010 23:00:00 +0100 4088582 http://www.medworm.com/index.php?rid=4088581&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20965956%26dopt%3DAbstract Conclusions In pericardial blood of patients undergoing cardiac surgery with CPB, microparticles contribute to activation of the complement system via bound SAP and IgM. Retransfusion of pericardial blood, however, does not contribute to systemic complement activation. PMID: 20965956 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4088581 Wed, 20 Oct 2010 23:00:00 +0100 4088581 http://www.medworm.com/index.php?rid=4044781&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20921084%26dopt%3DAbstract The objective of this study was to describe the effects of hydrodynamic characteristics of the oxygenator on energy transfer during pulsatile, normothermic CPB. Twenty-three adult patients scheduled for coronary bypass surgery were divided randomly into two groups, using either an oxygenator (Group 1) with a relatively high-resistance and low-compliance (2079 ± 148 dyn.s.cm(-5) and 0.00348 ± 0.00071 ml.mmHg(-1), respectively) or an oxygenator (Group 2) with a relatively low-resistance and high-compliance (884 ± 464 dyn.s.cm(-5) and 0.01325 ± 0.00161 ml.mmHg(-1), respectively). During perfusion, pre- and post-oxygenator pressures, radial artery pressure, and blood flow were recorded simultaneously. A 32% decline of mean pressure was observed in Group 1 and a 16% decline in Group 2 (p&lt... Perfusion journals http://www.medworm.com/rss/comments.php?id=4044781 Sun, 03 Oct 2010 23:00:00 +0100 4044781 http://www.medworm.com/index.php?rid=4044780&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20921085%26dopt%3DAbstract CONCLUSIONS: Preoperative administration of either methylprednisolone or atorvastatin reduced pro-inflammatory cytokine release, improved haemodynamics, decreased postoperative atrial fibrilation rate and reduced ICU stay in patients with significantly impaired cardiac function undergoing coronary revascularization. Treatment with methylprednisolone was associated with less inotropic support requirements and reduced mechanical ventilation time. PMID: 20921085 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4044780 Sun, 03 Oct 2010 23:00:00 +0100 4044780 http://www.medworm.com/index.php?rid=4044779&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20921086%26dopt%3DAbstract Authors: Lentini S, Gaeta R Antegrade cerebral perfusion (ACP) is used widely, with the aim of obtaining cerebral protection during open aortic arch surgery. ACP is considered by many to be the reason for improvements in the clinical outcome of this type of surgery. However, perioperative cerebral complications may still occur. Cerebral complications during ACP are considered to be due mainly to embolic events rather than hypoperfusion. We believe that many of the embolic events during ACP may be due to air embolism rather than to vessel manipulation only. To reduce the risk of air embolism during ACP, we propose an easy technique, with the suggested steps to be followed in an exact sequence. PMID: 20921086 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4044779 Sun, 03 Oct 2010 23:00:00 +0100 4044779 http://www.medworm.com/index.php?rid=4044778&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20921087%26dopt%3DAbstract CONCLUSION: Careful mobilization of the heart is recommended during surgery. In this case, it was unexpected that the tumor made its way through the vent line and unidirectional valve up to the venous reservoir where it was fortunately found. PMID: 20921087 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4044778 Sun, 03 Oct 2010 23:00:00 +0100 4044778 http://www.medworm.com/index.php?rid=4044777&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20921088%26dopt%3DAbstract In this report, we present two cases that developed contrast-induced encephalopathy following coronary angioplasty by the non-ionic contrast agent, iopromide (Ultravist(®)). As a result, we concluded that iopromide-induced encephalopathy may occur during angioplasty in patients with no particular predispositions. In addition to that, contrast-induced encephalopathy should be considered as a new-onset neurological disorder. PMID: 20921088 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=4044777 Sun, 03 Oct 2010 23:00:00 +0100 4044777 http://www.medworm.com/index.php?rid=3955402&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20826508%26dopt%3DAbstract Authors: Wong I, Vuylsteke A A large proportion of critically ill H1N1/2009 patients with respiratory failure subsequently developed ARDS and, to date, about 400 patients receiving extracorporeal life support (ECLS) have been accounted for globally, with a reported survival rate from 63% to 79%. The survival rates of patients with ARDS due to non-H1N1/2009 infections are similar. There is no definite evidence to suggest that patient outcomes are changed by ECLS, but its use is associated with serious short-term complications. ECLS relies on an extracorporeal circuit, with extracorporeal membrane oxygenation (ECMO) and pumpless interventional lung assist (ILA) being the two major types employed in ARDS. Both have the potential to correct respiratory failure and related haemodynamic inst... Perfusion journals http://www.medworm.com/rss/comments.php?id=3955402 Tue, 07 Sep 2010 23:00:00 +0100 3955402 http://www.medworm.com/index.php?rid=3912225&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20798136%26dopt%3DAbstract Authors: Issitt R, Sheppard S The pathological effects of pericardial suction blood (PSB) have been well described in numerous studies for many years; yet, despite this, there is no definitive answer to the question of how best to attenuate this pathology. More recently, large studies have shown that, whilst PSB contains many factors indicating its pathological potential, the direct re-infusion of PSB and residual pump volume (RPV) after cardiopulmonary bypass (CPB) potentially reduces the risk of transfusion and is no more harmful to the patient than the re-infusion of cell salvage-processed PSB after CPB. We conducted a telephone audit of UK perfusion units to determine if current protocols and practices reflected this. We found that there is a definite majority processing RPV with c... Perfusion journals http://www.medworm.com/rss/comments.php?id=3912225 Wed, 25 Aug 2010 23:00:00 +0100 3912225 http://www.medworm.com/index.php?rid=3912226&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20739351%26dopt%3DAbstract Authors: McKay C, Allen P, Jones PM, Chu MW Surgical treatment of patients who present with large aneurysms of the ascending aorta, transverse arch and descending aorta, including the thoracic and abdominal aorta typically consists of a two-staged elephant trunk procedure. Typically, these operations are lengthy, requiring long cardiopulmonary bypass times, deep hypothermic circulatory arrest and multiple anastamotic suture lines, which increases the risks for coagulopathic bleeding and the need for massive transfusions. The purpose of this report is to describe our approach, involving advanced surgical techniques and the innovative perfusion considerations as well as modified blood management strategies to minimize perioperative blood loss and the need for transfusions. All of the abo... Perfusion journals http://www.medworm.com/rss/comments.php?id=3912226 Tue, 24 Aug 2010 23:00:00 +0100 3912226 http://www.medworm.com/index.php?rid=3912227&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20736244%26dopt%3DAbstract In conclusion, a CPB blood flow based on an individual estimate did not improve cerebral and systemic oxygenation compared to a blood flow based on BSA. PMID: 20736244 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=3912227 Mon, 23 Aug 2010 23:00:00 +0100 3912227 http://www.medworm.com/index.php?rid=3900454&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20729257%26dopt%3DAbstract Authors: Griffith KE, Jenkins E The Abiomed Impella((R)) 2.5 is a micro-axial flow, catheter-based left ventricular assist system (LVAS). Designed for percutaneous insertion into the femoral artery and positioned across the aortic valve, the Impella((R)) is capable of pumping 2.5 liters of blood per minute from the patient's left ventricle into the ascending aorta. Since United States Federal Food and Drug Administration clearance in June of 2008, use of the Impella((R) ) 2.5 has grown rapidly. We operate at the center of a "hub-and-spoke" regional referral network that facilitates the transfer of patients in cardiogenic shock to our facility for definitive care. Based on our recent experience of transporting patients supported on the Impella((R)) 2.5 system, we review system operation... Perfusion journals http://www.medworm.com/rss/comments.php?id=3900454 Thu, 19 Aug 2010 23:00:00 +0100 3900454 http://www.medworm.com/index.php?rid=3873027&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20705643%26dopt%3DAbstract Authors: Dogra N, Puri GD, Rana SS Cardiac surgery involving cardiopulmonary bypass (CPB) in its conventional form involves many processes leading to free radical production, such as perioperative ischemia, reperfusion, circulation of whole body blood through the CPB circuit, hypothermia and acidosis. The red blood cells of a glucose-6-phosphate dehydrogenase (G6PD)-deficient person are unable to scavenge these free radicals, resulting in haemolysis. Here, we describe the successful anaesthetic management of two G6PD-deficient children who underwent cardiac surgery, on and off CPB, without any obvious haemolytic reaction, followed by a discussion of the disorder, with specific consideration of perioperative management of such cases. PMID: 20705643 [PubMed - as supplied by publisher... Perfusion journals http://www.medworm.com/rss/comments.php?id=3873027 Wed, 11 Aug 2010 23:00:00 +0100 3873027 http://www.medworm.com/index.php?rid=3873028&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20702519%26dopt%3DAbstract CONCLUSIONS: CD200R expression on granulocytes was significantly increased, while CD200 and CD200R expression on monocytes was decreased after cardiac surgery. PMID: 20702519 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=3873028 Tue, 10 Aug 2010 23:00:00 +0100 3873028 http://www.medworm.com/index.php?rid=3873030&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20699286%26dopt%3DAbstract Authors: Hargrove M, Marshall C, Jahanjir S, Hinchion J A 34-year-old male undergoing percutaneous atrial ablation procedure for paroxysmal fibrillation required emergency sternotomy for cardiac tamponade. The patient had been anticoagulated and had received plavix and aspirin prior to and during the ablation procedure. Seven units of red cell concentrate had been transfused in the cardiac catherisation laboratory. On arrival in theatre, the patient was hypotensive, but was awake on induction of anaesthesia. No recordable blood pressure with non-invasive monitoring was observed. A sternotomy was immediately performed and, on evacuation of the pericardium, a bleeding site was not visible. The patient was commenced on cardiopulmonary bypass. Bleeding site was identified and the defect cl... Perfusion journals http://www.medworm.com/rss/comments.php?id=3873030 Mon, 09 Aug 2010 23:00:00 +0100 3873030 http://www.medworm.com/index.php?rid=3873029&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20699287%26dopt%3DAbstract This study investigated the new QUADROX-i Neonatal Oxygenator (D-72145, Maquet, Hirrlingen, Germany) with an integrated arterial filter in terms of the hemodynamic properties and ability to clear GME in response to hypothermic versus normothermic conditions, open versus closed arterial filter purge line, and varying flow rates in a simulated CPB circuit identical to that of the clinical setting. A flow probe, pressure transducer, and Emboli Detection and Classification (EDAC) quantifier transducer were placed upstream and downstream to the oxygenator to measure changes in each parameter. The circuit was primed with fresh human blood with an hematocrit (Hct) of 26% diluted with Ringer's lactate solution. Five milliliters of air were injected proximal to the venous cardiotomy reservoir, unde... Perfusion journals http://www.medworm.com/rss/comments.php?id=3873029 Mon, 09 Aug 2010 23:00:00 +0100 3873029 http://www.medworm.com/index.php?rid=3855538&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20696738%26dopt%3DAbstract We report on a 49-year-old male patient who suffered from severe herpes simplex (HSV) pneumonia after a fall-from-height injury, causing a circumscript type B aortic dissection. The subsequent occurrence of ARDS required a veno-venous ECMO circuit that was upgraded to a veno-arterial system due to further oxygenation deficits. Following continued respiratory deterioration, the ECMO system already in place had to be complemented by a second veno-arterial line. After the onset of recovery and because of a developing of a disseminated intravasal coagulation, the double ECMO circuit was replaced by a pumpless extracorporeal lung assist system (PECLA). The patient recovered completely under systemic virostatic therapy. PMID: 20696738 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=3855538 Sun, 08 Aug 2010 23:00:00 +0100 3855538 http://www.medworm.com/index.php?rid=3855524&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20696739%26dopt%3DAbstract Authors: Yang J, Wang B, Xu R, Wang L This paper is a description of the designing of a new mainstream device to measure human respiration carbon dioxide concentration, based on non-dispersive infrared (NDIR) absorption technology. The device can be used to accurately monitor the cardiopulmonary status during anaesthesia and mechanical ventilation in real time. This new device can not only make up the error of real-time gas measurement of the side-stream device, but also make up the accuracy of the main-stream device. In the paper, four issues which can affect the measurement accuracy were considered: respiration gas flow, turbulence of the light source with all ranges of wavelength, temperature drift and signal noise. The experimental results showed that the device could produce a sta... Perfusion journals http://www.medworm.com/rss/comments.php?id=3855524 Sun, 08 Aug 2010 23:00:00 +0100 3855524 http://www.medworm.com/index.php?rid=3824378&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20675340%26dopt%3DAbstract Authors: Lentini S, Gaeta R PMID: 20675340 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=3824378 Thu, 29 Jul 2010 23:00:00 +0100 3824378 http://www.medworm.com/index.php?rid=3795419&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20659972%26dopt%3DAbstract CONCLUSIONS: Pre-operative impaired left ventricular function is an important risk factor for failure of CVVHD in the treatment of ARF after cardiac surgery. The sooner CVVHD is instituted the better prognosis may be. PMID: 20659972 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=3795419 Tue, 20 Jul 2010 23:00:00 +0100 3795419 http://www.medworm.com/index.php?rid=3777573&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20647245%26dopt%3DAbstract Conclusions: Fast rewarming with strict avoidance of hyperthermia after DHCA in rats was accompanied by pronounced histologic damage and accentuated cerebral NFkappaB expression. PMID: 20647245 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=3777573 Mon, 19 Jul 2010 23:00:00 +0100 3777573 http://www.medworm.com/index.php?rid=3777574&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20634225%26dopt%3DAbstract Authors: Fitzgerald D, Ging A, Burton N, Desai S, Elliott T, Edwards L A 65-year-old male with a known history of ischemic cardiomyopathy was admitted to the intensive care unit in cardiogenic shock. Cardiac catheterization revealed bi-ventricular hypokinesis, with an estimated ejection fraction of 15%. Despite moderate inotropic support, the patient's liver enzymes, international normalization ratio (INR), and creatinine became grossly elevated, indicating multi-organ injury from hypoperfusion. Due to the patient's state of shock and probable bleeding complications, a full sternotomy and emergent biventricular assist device insertion was deemed very high risk. In order to achieve hemodynamic stability, a decision was made for extracorporeal membrane oxygenation (ECMO) support. ECMO su... Perfusion journals http://www.medworm.com/rss/comments.php?id=3777574 Wed, 14 Jul 2010 23:00:00 +0100 3777574 http://www.medworm.com/index.php?rid=3761709&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20630918%26dopt%3DAbstract Authors: Augustin S, Horton A, Butt W, Bennett M, Horton S During extracorporeal life support (ECLS), blood is exposed to a myriad of unphysiological factors that can affect outcome. One aspect of this is the sub-atmospheric pressure generated by the ECLS pump and imparted to blood elements along the pump inlet line. This pressure can be measured on the inlet line close to the pump head by adding a connector, or at the venous cannula connection site. We compared the two measurement sites located at both points; between the venous cannula-inlet tubing and inlet tubing-pump, with a range of cannulae and flows. We also investigated the effects on inlet pressure from pump afterload and increasing inlet tubing length. PMID: 20630918 [PubMed - as supplied by publisher] (Source: Perfusion... Perfusion journals http://www.medworm.com/rss/comments.php?id=3761709 Tue, 13 Jul 2010 23:00:00 +0100 3761709 http://www.medworm.com/index.php?rid=3761708&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20630919%26dopt%3DAbstract Conclusions: In comparison with data from the recent literature, the reported number of incidents is high. Nevertheless, the adverse outcome rate is well matched to other published surveys. The relatively high response rate conveys the impression that the Dutch perfusionist is vigilant and willing to report incidents. Hence, a web-based Dutch perfusion incident registration system is recommended. PMID: 20630919 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=3761708 Tue, 13 Jul 2010 23:00:00 +0100 3761708 http://www.medworm.com/index.php?rid=3761707&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20630920%26dopt%3DAbstract The objective of this study was to find out the effect of various doses of hydroxyethyl starch (HES), gelatine or Ringer's acetate on cardiac and stroke volume index after cardiac surgery. Material and methods: Three consecutive boluses (each 7 mL.kg(-1)) of either 6% HES 130/0.4, 4% gelatine, or Ringer's acetate solutions were administered to 45 patients postoperatively. The rate of infusions was adjusted according to haemodynamic measurements. Thereafter, infusion of the study solution (7 mL.kg(-1)) was continued for the following 12 hours. The total dose of study solution was 28 mL. kg(-1). Results and conclusion: Mean (SD) cardiac and stroke volume indices were greater in the HES group [2.8 L.min(-1).m(-2) (0.7), 34.1 (6.7) ml.m(-2)] than in the gelatine group [2.2 L. min(-1).m(-2) (0.... Perfusion journals http://www.medworm.com/rss/comments.php?id=3761707 Tue, 13 Jul 2010 23:00:00 +0100 3761707 http://www.medworm.com/index.php?rid=3761711&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20627941%26dopt%3DAbstract Authors: Reznik O, Bagnenko S, Scvortsov A, Loginov I, Ananyev A, Senchik K, Moysyuk Y The unexploited potential of donors after cardiac death is an actual issue for all countries where organ transplantation is performed. The crucial point in uncontrolled donation after cardiac death is the warm ischemic time. The primary purpose of our work was to define the limits of warm ischemic time. Another purpose was the development of an in situ kidney preservation protocol. In 8 uncontrolled donors with warm ischemic time from 45 to 91 minutes, a normothermic extracorporeal perfusion device was applied, providing preservation and restoration of the kidney after ischemic damage. Main attention was paid to the elimination of leukocytes as the key damaging factor from modified donor blood circul... Perfusion journals http://www.medworm.com/rss/comments.php?id=3761711 Mon, 12 Jul 2010 23:00:00 +0100 3761711 http://www.medworm.com/index.php?rid=3761710&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20627942%26dopt%3DAbstract CONCLUSION: AT can be infused at a rate of 250 IU/min. This is faster than the current recommendation of 100 IU/min. This rate of infusion allows restricting AT infusion to those patients who display HR, without delaying surgery. Optimal anticoagulant therapy for CPB probably includes point-of-care measurement of ACT and plasma AT and small, but rapid, infusions of AT in heparin-resistant patients. PMID: 20627942 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=3761710 Mon, 12 Jul 2010 23:00:00 +0100 3761710 http://www.medworm.com/index.php?rid=3734287&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20605871%26dopt%3DAbstract Authors: Gagnon J, Laporta D, Béïque F, Langlois Y, Morin JF The current clinical study is the continuity of previous experimental findings in which ventilation during cardiopulmonary bypass (CPB) prevented reperfusion injury of the pulmonary arterial tree as demonstrated by preservation of vasorelaxation to acetylcholine (ACh) in swine. The aim of this prospective randomized study is to determine: 1) if ventilation during CPB prevents the selective endothelium-mediated lung dysfunction in humans and, 2) the clinical relevance of ventilation during CPB. Forty patients scheduled for primary coronary artery bypass grafting (CABG) were randomized into two groups: Group 1: Usual care (defined as no ventilation during CPB) and Group 2: CPB with low tidal volume ventilation (3 ml.kg(-1... Perfusion journals http://www.medworm.com/rss/comments.php?id=3734287 Mon, 05 Jul 2010 23:00:00 +0100 3734287 http://www.medworm.com/index.php?rid=3702092&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20576727%26dopt%3DAbstract We present an assessment of practical measures that were also adapted in our institution to achieve an asanguinous CPB for neonatal and infant patients. PMID: 20576727 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=3702092 Wed, 23 Jun 2010 23:00:00 +0100 3702092 http://www.medworm.com/index.php?rid=3702091&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20576728%26dopt%3DAbstract Authors: Thiara A, Eggereide V, Pedersen T, Lindberg H, Fiane A The neonate cardiopulmonary bypass (CPB) circuit, including a KIDS D100 oxygenator (The Sorin Group, Mirandola, Italy) and a D130 arterial filter (The Sorin Group), was evaluated in vitro with respect to the removal of free micro gas bubbles. No gas bubbles > 40microm were measured after the arterial filter D130 upon manual introduction of 10 ml of air into the venous line or during the use of vacuum-assisted venous drainage (VAVD). The D130 arterial filter removed 88 % of gas bubbles < 40 microm during manual introduction of air into the venous line; however, only 50 % of gas bubbles < 40 microm were removed during the use of VAVD. The same CPB circuit was evaluated in vivo to compare with another CPB circuit, in... Perfusion journals http://www.medworm.com/rss/comments.php?id=3702091 Wed, 23 Jun 2010 23:00:00 +0100 3702091 http://www.medworm.com/index.php?rid=3702095&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20573652%26dopt%3DAbstract CONCLUSION: Venoarterial ECMO reduces systemic venous pressure while maintaining or improving systemic perfusion in both a normal circulatory state and in the setting of increased right ventricular load associated with acute lung injury. ECMO may be a useful tool in reducing blood loss during major venous hemorrhage in both trauma and selected elective surgery. PMID: 20573652 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=3702095 Tue, 22 Jun 2010 23:00:00 +0100 3702095 http://www.medworm.com/index.php?rid=3702094&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20573653%26dopt%3DAbstract CONCLUSION: The self-expanding cannula exhibited superior venous drainage ability when compared to the performance of the standard rectilinear cannula with the use of the LifeBox. The flow rate achieved was approximately 40% greater than the standard drainage device, with a maximal pump flow recorded at 4.3l/min. PMID: 20573653 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=3702094 Tue, 22 Jun 2010 23:00:00 +0100 3702094 http://www.medworm.com/index.php?rid=3702093&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20573654%26dopt%3DAbstract Authors: Argiriadou H, Megari K, Antonitsis P, Kosmidis MH, Papakonstantinou C, Anastasiadis K Concerns about the potential impact of the non-pulsatile circulation pattern generated by the new generation axial-flow left ventricular assist devices on neurocognitive function led us to evaluate a patient in whom a Jarvik 2000 pump was implanted. We assessed the patient's baseline neurocognitive function preoperatively as well as at 1-month and 6-month follow-up, using a comprehensive battery of neuropsychological tests. A slight improvement in circumscribed neurocognitive domains was noted, with no evidence of further decline at the end of a 6-month follow-up period. PMID: 20573654 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=3702093 Tue, 22 Jun 2010 23:00:00 +0100 3702093 http://www.medworm.com/index.php?rid=3691910&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20566585%26dopt%3DAbstract Conclusions: The combination of the Baby RX-05 oxygenator and Capiox AF02 arterial line filter provides the highest level of protection from air emboli in an in vitro investigation. PMID: 20566585 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=3691910 Sun, 20 Jun 2010 23:00:00 +0100 3691910 http://www.medworm.com/index.php?rid=3691909&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20566586%26dopt%3DAbstract Authors: Mongero LB, Brodie D, Cunningham J, Ventetuolo C, Kim H, Sylvan E, Bacchetta M Liquid silicone is an inert material that may be used for cosmetic procedures by physicians as well as illegally by non-medical personnel. The use of silicone may result in severe complications, disfigurement, and even death. In addition, the indications for extracorporeal membrane oxygenation (ECMO) support have been increasing as a salvage therapy for a variety of life-threatening conditions. The patient is a 27-year-old woman with no significant medical conditions who developed silicone emboli, and subsequent diffuse alveolar hemorrhage after being injected with silicone in her gluteal region without medical supervision. She became profoundly hypoxemic and suffered a brief asystolic cardiac arres... Perfusion journals http://www.medworm.com/rss/comments.php?id=3691909 Sun, 20 Jun 2010 23:00:00 +0100 3691909 http://www.medworm.com/index.php?rid=3662997&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20530518%26dopt%3DAbstract CONCLUSION: Both Sonoclot and TAT failed to predict the VFS. No patient had any clinical clotting events and all dialyses were completed successfully. PMID: 20530518 [PubMed - as supplied by publisher] (Source: Perfusion) Perfusion journals http://www.medworm.com/rss/comments.php?id=3662997 Mon, 07 Jun 2010 23:00:00 +0100 3662997 http://www.medworm.com/index.php?rid=3626501&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20515982%26dopt%3DAbstract Authors: Anastasiadis K, Asteriou C, Deliopoulos A, Argiriadou H, Karapanagiotidis G, Antonitsis P, Grosomanidis V, Missias G, Papakonstantinou C During the last decade, minimized extracorporeal circulation (MECC) systems have shown beneficial effects to the patients over the conventional cardiopulmonary bypass (CECC) circuits. This is a prospective randomized study of 99 patients who underwent coronary artery bypass grafting (CABG) surgery, evaluating the postoperative haematological effects of these systems. Less haemodilution (p=0.001) and markedly less haemolysis (p<0.001), as well as better preservation of the coagulation system integrity (p=0.01), favouring the MECC group, was found. As a clinical result, less bank blood requirements were noted and a quicker recovery, as far a... Perfusion journals http://www.medworm.com/rss/comments.php?id=3626501 Mon, 31 May 2010 23:00:00 +0100 3626501 http://www.medworm.com/index.php?rid=3626500&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20515983%26dopt%3DAbstract We report a retrospective review of ten patients referred for surgical intervention from March 2008 to present. Nine patients were diagnosed with right coronary arteries arising from the left coronary cusp and one patient with a left coronary artery arising from the right coronary cusp. Seven patients were male and the median age was 40 years (range, 21 to 51). Symptoms included atypical chest pain, tachy-arrythmias, diaphoresis, and dyspnea on exertion. CTA demonstrated anomalous coronary arteries arising from the opposite coronary cusp and traveling between the aorta and the pulmonary artery. Surgical intervention was performed on all ten patients with no mortality and only one re-operation requiring bypass grafting. The sixth patient in the series had concomitant atherosclerotic disease... Perfusion journals http://www.medworm.com/rss/comments.php?id=3626500 Mon, 31 May 2010 23:00:00 +0100 3626500 http://www.medworm.com/index.php?rid=3539090&cid=s_38194_157_f&fid=38194&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20442203%26dopt%3DAbstract Authors: Fernandes P, Macdonald J, Cleland A, Walsh G, Mayer R The purpose of this study is to determine the appropriate arterial pump flow /cardiac index (CI) utilizing a mini-bypass system. The unique feature of most mini-bypass systems is that the centrifugal pump combines the function of kinetic venous drainage with arterial pump flow. Therefore, if drainage is reduced, arterial pump flow is also reduced. Managing this system can present challenges to the clinical perfusionist. We reviewed fifteen cases, using the Medtronic Resting Heart System (RHS). This retrospective study examined the arterial pump flow, measured as cardiac index (CI), mean arterial pressure, inlet venous saturation, urine output, vasopressor use, and lactate production during routine cardiac surgery. The mean ... Perfusion journals http://www.medworm.com/rss/comments.php?id=3539090 Mon, 03 May 2010 23:00:00 +0100 3539090