MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Progress in Neurology and Psychiatry' source. Sat, 31 Dec 2011 19:15:02 +0100 http://www.medworm.com/index.php?rid=5506858&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.221 AbstractNewsTreating personality disordersThe Department of Health has published its response to the consultation on a new pathway approach for the treatment and management of offenders with serious personality disorders (www.dh.gov.uk/health). It says ‘... it is clear ... that there is broad support for our plans and ... respondents agree that the National Offender Management Service (NOMS) and the NHS should work together to design and implement integrated pathways for managing and treating offenders with severe personality disorders, building on local and regional structures.’ The full response is available online.Coincidentally, NICE has been consulting on whether to update its 2009 clinical guideline (CG78) on borderline personality disorder. New clinical trial evidence about drug... Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=5506858 Tue, 01 Nov 2011 04:00:00 +0100 5506858 http://www.medworm.com/index.php?rid=5506857&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.220 AbstractYork Racecourse played host to the International League Against Epilepsy (ILAE) UK Chapter's 2011 annual scientific meeting in November, with over 300 delegates attending from all over the UK. Dr Joseph Anderson, Specialist Registrar and Clinical Teaching Fellow from the University Hospital of Wales, Cardiff, reports on some of the main highlights of the meeting. Copyright © 2011 John Wiley & Sons, Ltd. (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=5506857 Tue, 01 Nov 2011 04:00:00 +0100 5506857 http://www.medworm.com/index.php?rid=5506856&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.219 AbstractRecent research suggests that aggregates of cytosolic proteins such as α‐synuclein may spread in a manner similar to prions in certain neurodegenerative diseases. Mark Greener explains how drugs that can reduce formation or increase clearance of these proteins may represent new treatment strategies for Parkinson's disease. Copyright © 2011 John Wiley & Sons, Ltd. (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=5506856 Tue, 01 Nov 2011 04:00:00 +0100 5506856 http://www.medworm.com/index.php?rid=5506855&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.218 AbstractMost people with bipolar disorder first seek treatment for depressive rather than manic symptoms. However, effective management of bipolar depression remains a challenge. In this review, Celia Feetam highlights how bipolar depression differs from unipolar depression both in its characteristics and in the approach to its treatment. Copyright © 2011 John Wiley & Sons, Ltd. (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=5506855 Tue, 01 Nov 2011 04:00:00 +0100 5506855 http://www.medworm.com/index.php?rid=5506854&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.217 AbstractSupervised Community Treatment (SCT) was introduced in 2008 as part of the 2007 Mental Health Act Amendments, allowing Community Treatment Orders (CTOs) to be imposed in certain circumstances. Here, Drs Monnery and Belgamwar investigate whether the new CTOs have been applied within their Trust according to guidelines. They also examine the reasons behind the CTOs and their impact on admission to hospital. Copyright © 2011 John Wiley & Sons, Ltd. (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=5506854 Tue, 01 Nov 2011 04:00:00 +0100 5506854 http://www.medworm.com/index.php?rid=5506853&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.216 AbstractIn recent studies, 3,4‐methylenedioxymethylamphetamine (MDMA) has shown promise in the treatment of post‐traumatic stress disorder (PTSD) as an adjunct to post‐trauma psychological therapy. However, because of historical associations with its use as the recreational drug ecstasy, MDMA research remains a controversial subject. Dr Sessa discusses these controversies and describes a UK‐based MDMA/PTSD currently in development. Copyright © 2011 John Wiley & Sons, Ltd. (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=5506853 Tue, 01 Nov 2011 04:00:00 +0100 5506853 http://www.medworm.com/index.php?rid=5338265&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.215 AbstractNewsNICE guideline on ADHDConsultation on the NICE guideline on ADHD (CG72) has now ended. The scheduled review will consider new evidence on diagnosis, management and the organisation of care emerging since the guideline was published in 2008. New clinical trials confirm current recommendations for the treatment of children, NICE says, and support the use of methylphenidate as firstline therapy in adults followed by atomoxetine or dexamfetamine for patients who do not respond to or who are intolerant of six weeks' treatment with methylphenidate.NICE stroke recommendationsAbout half of patients with suspected stroke are initially managed in line with NICE's recommendations, according to an audit by the Royal College of Physicians (www.rcplondon.ac.uk). The College's Stroke Improvem... Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=5338265 Thu, 01 Sep 2011 04:00:00 +0100 5338265 http://www.medworm.com/index.php?rid=5338264&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.214 (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=5338264 Thu, 01 Sep 2011 04:00:00 +0100 5338264 http://www.medworm.com/index.php?rid=5338263&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.213 AbstractTreatment challenges across the life course was the theme for the 10th Latest Advances in Psychiatry Symposium, held in London in March. Speakers addressed issues facing psychiatrists caring for patients from the teenage years right through to old age. Steve Titmarsh provides an overview of the key issues raised during the meeting. Copyright © 2011 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=5338263 Thu, 01 Sep 2011 04:00:00 +0100 5338263 http://www.medworm.com/index.php?rid=5338262&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.212 AbstractDepression is perhaps the most important mental health complication of cancer. While major depression is relatively uncommon and often missed, clinically significant mood disorders can occur in about 40 per cent of patients. In this review, Dr Mitchell discusses screening for depression in patients in cancer settings and outlines the current treatment options. Copyright © 2011 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=5338262 Thu, 01 Sep 2011 04:00:00 +0100 5338262 http://www.medworm.com/index.php?rid=5338261&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.211 In this study, the authors estimate the frequency of undiagnosed ADHD in four general adult psychiatry outpatient clinics in North East England, and investigate how effective two screening questionnaires are at identifying its presence. Copyright © 2011 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=5338261 Thu, 01 Sep 2011 04:00:00 +0100 5338261 http://www.medworm.com/index.php?rid=5338260&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.210 AbstractEarlier this year, the first ever cross‐governmental mental health strategy was launched, laying out plans for the future of mental healthcare in England.1 The Government has recognised that mental health is not simply a Department of Health issue in isolation but that it affects every area of a person's life and impacts upon their ability to play an active role in society. The strategy, however, is woolly, uncosted and lacks an implementation plan. It also fails to focus on the profound level of unmet service needs of people with serious mental illness. Copyright © 2011 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=5338260 Thu, 01 Sep 2011 04:00:00 +0100 5338260 http://www.medworm.com/index.php?rid=5111572&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.209 AbstractNewsNew models of mental health care for LondonLondon Health Programmes (www.londonhp.nhs.uk) has published new models of care for people experiencing a mental health crisis and for people with long‐term mental health conditions. Developed by service users, clinicians, commissioners and providers, Mental Health Models of Care for London aims to refocus existing services and staff rather than creating new services.Improving dementia research and supportThe Ministerial Advisory Group on Dementia Research has published a Headline Report for furthering research into dementia in the UK (www.dh.gov.uk/Publicationsandstatistics). Set up by the Government to consider how to increase the volume and impact of dementia research, the group proposes actions to strengthen collaboration and coo... Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=5111572 Thu, 30 Jun 2011 23:00:00 +0100 5111572 http://www.medworm.com/index.php?rid=5111571&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.208 AbstractHere, we bring readers extracts from the latest issues of The Cochrane Database of Systematic Reviews relevant to the fields of psychiatry and neurology. We feature a summary of the results, reviewers' conclusions, and implications for clinical practice and research, from selected new reviews featured in issues 6 and 7, 2011. For further information, visit www.thecochranelibrary.com. Copyright © 2011 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=5111571 Thu, 30 Jun 2011 23:00:00 +0100 5111571 http://www.medworm.com/index.php?rid=5111570&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.207 AbstractUnder the Quality Outcome Framework (QOF), points are awarded to GP practices that keep a dementia register and record patient reviews. The aim of this audit was to compare the East Cornwall Memory Service's database of diagnosed patients against the QOF registers for dementia held by nine GP practices in East Cornwall. Copyright © 2011 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=5111570 Thu, 30 Jun 2011 23:00:00 +0100 5111570 http://www.medworm.com/index.php?rid=5111569&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.206 AbstractA more rigorous and scientific approach to characterisation and diagnosis of mental illness, particularly among children, could help reduce the number of patients who do not respond to treatment. That was the view put forward by Professor Ian Goodyer, Professor of Child and Adolescent Psychiatry at Cambridge University in his Keynote Lecture at the 10th Latest Advances in Psychiatry Symposium held in London in March. Steve Titmarsh reports. Copyright © 2011 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=5111569 Thu, 30 Jun 2011 23:00:00 +0100 5111569 http://www.medworm.com/index.php?rid=5111568&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.205 AbstractThe casemix of an early‐onset dementia clinic is different from that usually seen by old age psychiatrists or geriatricians and includes frontotemporal lobar degeneration, prion disease and genetically determined dementia as well as Alzheimer's disease. This brief review summarises the causes, diagnostic considerations and management of early‐onset dementias based on the authors' experience of working in a neurology‐led cognitive function clinic at a regional neuroscience centre. Copyright © 2011 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=5111568 Thu, 30 Jun 2011 23:00:00 +0100 5111568 http://www.medworm.com/index.php?rid=5111567&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.204 AbstractThe imminent payment‐by‐results system for mental health in England means that Trusts need to reorganise delivery of care taking into account the new care pathway clusters. In this article, Dr Whelan and colleagues discuss the potential dilemmas and problems faced by the introduction of this system based on their own experience, with a particular focus on old age services. Copyright © 2011 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=5111567 Thu, 30 Jun 2011 23:00:00 +0100 5111567 http://www.medworm.com/index.php?rid=5111566&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.203 AbstractDopamine agonist withdrawal syndrome (DAWS) has recently been named in the Archives of Neurology. It describes a cluster of symptoms occurring in Parkinson's disease patients with impulse control disorders on tapering down or withdrawal of their dopamine agonist. Drs Lindahl and MacMahon discuss the risk factors for the development of DAWS and some approaches to its management. Copyright © 2011 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=5111566 Thu, 30 Jun 2011 23:00:00 +0100 5111566 http://www.medworm.com/index.php?rid=4939922&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.202 AbstractNewsNew DH report on mental health promotionThe Department of Health has published an economic evaluation of the benefits of mental health promotion and preventing mental illness (www.dh.gov.uk/prod_consum_dh/groups/dh_digitalassets/documents/digitalasset/dh_126386.pdf). Edited by Professor Martin Knapp and colleagues from the London School of Economics and Political Science, with contributions from researchers based largely in the south east of England, the 43‐page report summarises the financial burden and cost effectiveness of interventions to tackle a range of mental health issues in the home, school and workplace. It concludes that many interventions offer outstanding value for money and several are cost‐saving, though the pay‐off period can be several years.Safinamide h... Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=4939922 Sat, 30 Apr 2011 23:00:00 +0100 4939922 http://www.medworm.com/index.php?rid=4939921&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.201 (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=4939921 Sat, 30 Apr 2011 23:00:00 +0100 4939921 http://www.medworm.com/index.php?rid=4939920&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.200 AbstractCost is a major focus in healthcare, and in the current economic climate the pressure to reduce costs is greater than ever. The latest round of organisational changes proposed for the NHS may encourage new thinking about commissioning and delivery of care, as well as the way the total cost of one treatment is compared with another. Some of the issues in managing mental healthcare costs within the NHS were discussed at a satellite symposium, organised by Lundbeck Ltd, held at the 10th Latest Advances in Psychiatry Symposium in London in March. Steve Titmarsh reports. Copyright © 2011 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=4939920 Sat, 30 Apr 2011 23:00:00 +0100 4939920 http://www.medworm.com/index.php?rid=4939919&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.199 AbstractChallenging behaviour is a very common problem in older people with dementia. It can increase caregiver stress, reduce quality of life and increase the risk of institutionalisation and admission to hospital. Here, Dr Krishnamoorthy and Dr Anderson discuss the aetiology and treatment of challenging behaviour, emphasising that understanding the reasons behind the behaviour is the key to effective management. Copyright © 2011 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=4939919 Sat, 30 Apr 2011 23:00:00 +0100 4939919 http://www.medworm.com/index.php?rid=4939918&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.198 AbstractDiagnosis of attention deficit‐hyperactivity disorder (ADHD) is traditionally based on subjective assessments of behaviour by clinicians and carers in different settings, but this approach is prone to biases. Recent advances in computerised continuous performance task (CPT) tests have greatly improved their clinical utility in ADHD. In this article, the authors review the history of computerised CPT tests and their potential role in the diagnosis and management of children and adolescents with ADHD. Copyright © 2011 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=4939918 Sat, 30 Apr 2011 23:00:00 +0100 4939918 http://www.medworm.com/index.php?rid=4939917&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.197 AbstractHere, Dr de Silva discusses the discrepancies in our knowledge of the pathogenesis of schizophrenia and the different approaches to its management, and suggests some solutions on how these differences may be overcome. Copyright © 2011 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=4939917 Sat, 30 Apr 2011 23:00:00 +0100 4939917 http://www.medworm.com/index.php?rid=4939916&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.196 AbstractIn their article on managing challenging behaviour in older people with dementia (page 20), Dr Krishnamoorthy and Dr Anderson highlight the importance of a person‐centred approach to dementia care. However, several recent reports indicate that elderly patients may not always receive the care they deserve in UK hospitals. Copyright © 2011 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=4939916 Sat, 30 Apr 2011 23:00:00 +0100 4939916 http://www.medworm.com/index.php?rid=4749675&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.195 AbstractNewsPaliperidone for schizophreniaJanssen‐Cilag has received European approval for Xeplion, its once monthly long‐acting injectable formulation of paliperidone palmitate, for the treatment of schizophrenia in adults previously treated with oral paliperidone or the parent compound risperidone. The company says clinical trials have shown the treatment is superior to placebo in acute episodes and relapse prevention. Xeplion will be available in five strengths of a prolonged‐release suspension.Tasimelteon for chronic circadian sleep disorderA new oral melatonin receptor agonist has been granted orphan drug status by the European Commission. Clinical trials have shown that tasimelteon may be effective in the treatment of non‐24‐hour sleep/wake disorder, a chronic circadian rhy... Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=4749675 Tue, 01 Mar 2011 00:00:00 +0100 4749675 http://www.medworm.com/index.php?rid=4749674&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.194 AbstractWhile patient choice is key when deciding on medication for patients with attention deficithyperactivity disorder (ADHD), doctors can sometimes unwittingly impose their views if the patient is unsure or unclear. Here, three specialists in the field discuss whether enough time is spent with patients examining and explaining the options, and if drugs are properly tailored to the needs of the patient. This discussion covers areas including approach to diagnosis and what factors should be considered when deciding on a particular drug treatment. Copyright © 2011 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=4749674 Tue, 01 Mar 2011 00:00:00 +0100 4749674 http://www.medworm.com/index.php?rid=4749673&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.193 This study investigates its utility for the diagnosis of dementia in a cognitive function clinic. Copyright © 2011 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=4749673 Tue, 01 Mar 2011 00:00:00 +0100 4749673 http://www.medworm.com/index.php?rid=4749672&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.192 AbstractThe prevalence of migraine is highest during the peak reproductive years and many women report its association with their menstrual periods. In this review, Professor MacGregor discusses the diagnosis, pathophysiology and management of menstrual migraine. Copyright © 2011 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=4749672 Tue, 01 Mar 2011 00:00:00 +0100 4749672 http://www.medworm.com/index.php?rid=4749671&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.191 AbstractIn the September/October 2009 issue of Progress in Neurology and Psychiatry, we featured an article describing a promising new 2D robotic and electronic stimulation system developed at the University of Southampton for rehabilitation of arm movement following stroke. Here, the scientists who developed the system describe a further extension of the technique to a new 3D system known as SAIL (Stimulation Assistance through Iterative Learning). Copyright © 2011 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=4749671 Tue, 01 Mar 2011 00:00:00 +0100 4749671 http://www.medworm.com/index.php?rid=4749670&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.190 AbstractMost of us will welcome the new mental health strategy for England No Health Without Mental Health,1 which aims to transform the mental health and well‐being of the nation with an ambition to mainstream mental health and achieve ‘parity of esteem’ with physical health. The aim is for mental health to be ‘everyone's business’ – including Local Government, employers, education and the third sector. Copyright © 2011 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=4749670 Tue, 01 Mar 2011 00:00:00 +0100 4749670 http://www.medworm.com/index.php?rid=4452153&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.189 AbstractDepression and anxietyDepression‐related insomniaLong‐term use of hypnotics is frowned on but US investigators have found that a modified‐release formulation of zolpidem has sustained benefits in patients with depression‐related insomnia (J Clin Psychiatry 2011;doi:10.4088/ JCP.09m05571gry). Compared with placebo over eight weeks in individuals taking concomitant escitalopram, zolpidem 12.5mg nightly improved total sleep time, sleep quality and measures of functioning the next day, and reduced sleep onset latency and number of awakenings. It had no effect on scores of depression or quality of life. Some individuals continued treatment for a further 16 weeks, with similar results.Home‐based careService models can also influence the outcome of treatment: in an Austrian stud... Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=4452153 Sat, 01 Jan 2011 00:00:00 +0100 4452153 http://www.medworm.com/index.php?rid=4452152&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.188 In this study, the authors assessed the appropriateness of GP referrals to their community general adult mental health services of patients with anxiety and depression, according to the NICE guidelines. Copyright © 2011 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=4452152 Sat, 01 Jan 2011 00:00:00 +0100 4452152 http://www.medworm.com/index.php?rid=4452151&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.187 AbstractElectroconvulsive therapy (ECT) is a psychiatric treatment with a controversial history. Advances in technology have led to a safer therapy, making it once again an option in very specific circumstances. Here, Dr Singhal discusses its current role in the management of depression. Copyright © 2011 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=4452151 Sat, 01 Jan 2011 00:00:00 +0100 4452151 http://www.medworm.com/index.php?rid=4452150&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.186 AbstractPatients with chronic neurological conditions such as Huntington's disease require the input of a multidisciplinary team to meet their complex needs. Here, the authors describe their specialist clinic in North Staffordshire for patients with Huntington's disease, which offers a one‐stop shop for access to health professionals from many different disciplines. Copyright © 2011 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=4452150 Sat, 01 Jan 2011 00:00:00 +0100 4452150 http://www.medworm.com/index.php?rid=4452149&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.185 AbstractThe impact of migraine on quality of life is often vastly underestimated. Kate Scurr, Press and PR Manager at The Migraine Trust, outlines the work the Trust is doing to improve the quality of life of the millions of migraine sufferers in the UK. Copyright © 2011 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=4452149 Sat, 01 Jan 2011 00:00:00 +0100 4452149 http://www.medworm.com/index.php?rid=4452148&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.184 AbstractThe 2010 Department of Health White Paper Equity and Excellence: Liberating the NHS1 outlines plans to place commissioning in the hands of new GP consortia, thus breaking down the primary/secondary care divide. In this article, Dr Hashmi and Professor Mortimer discuss what they think the changes will mean for community mental health services. Copyright © 2011 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=4452148 Sat, 01 Jan 2011 00:00:00 +0100 4452148 http://www.medworm.com/index.php?rid=4452147&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.183 AbstractBeing invited to write an editorial about a book1 I myself authored, is a rather strange experience. I wondered how best to approach the task, and decided, in the 500 or so allotted words, to address what is perhaps the most intriguing question for any author now as we enter the second decade of the age of the internet, namely: ‘Are medical books still required?’. Copyright © 2011 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=4452147 Sat, 01 Jan 2011 00:00:00 +0100 4452147 http://www.medworm.com/index.php?rid=4261288&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.182 AbstractAnxiety and depressionAntidepressant weight gain Anti ‐ depressants are another class of drugs associated with weight gain but a new meta‐analysis of 116 studies identifies some that carry the greatest risk (J Clin Psychiatry 2010;71:1259‐72). Amitriptyline, mirtazapine and paroxetine were associated with the highest risk of weight gain whereas bupropion and acute use of fluoxetine were associated with weight loss. Evidence for other agents was inconclusive.Anxiolytic abuse Drugs for anxiety have abuse potential and, say US investigators, there is a link between prescribing and abuse (Am J Psychiatry 2010;167:1247‐53). Using national survey data from 34 653 adults, they found that the prescription of anxiety medication was associated with a 90 per cent increased risk of non... Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=4261288 Mon, 01 Nov 2010 00:00:00 +0100 4261288 http://www.medworm.com/index.php?rid=4261287&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.181 AbstractBrighton – famous for its piers, ideas and pioneers – played host to the annual International League Against Epilepsy (ILAE) UK Chapter meeting in October. Here, Dr Rhys Thomas, Clinical Lecturer in Neurology at Cardiff and Swansea University, provides an overview of the highlights of the meeting. Copyright © 2010 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=4261287 Mon, 01 Nov 2010 00:00:00 +0100 4261287 http://www.medworm.com/index.php?rid=4261286&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.180 AbstractThe 26th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) was held in Gothenberg, Sweden in October, attracting 6300 participants from around the world. Katherine Laight reports on some of the highlights of the Congress. Copyright © 2010 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=4261286 Mon, 01 Nov 2010 00:00:00 +0100 4261286 http://www.medworm.com/index.php?rid=4261285&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.179 AbstractYoungMinds is a UK charity committed to improving the emotional wellbeing and mental health of children and young people and empowering their parents and carers. Hannah Smith, Senior Media and Campaigns Officer at YoungMinds, outlines the work the charity is doing to help young people with mental health problems and ensure their wellbeing. Copyright © 2010 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=4261285 Mon, 01 Nov 2010 00:00:00 +0100 4261285 http://www.medworm.com/index.php?rid=4261284&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.178 AbstractAbulia is a state of diminished motivation in which an individual may appear apathetic, disinterested, asocial and emotionally remote. There is currently a lack of information on the recognition and management of abulia in elderly patients, despite the fact that it occurs in conjunction with many conditions that are associated with ageing. Here, the authors review the current literature and describe three cases of abulia in elderly patients that responded well to treatment with bromocriptine. Copyright © 2010 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=4261284 Mon, 01 Nov 2010 00:00:00 +0100 4261284 http://www.medworm.com/index.php?rid=4261283&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.177 AbstractDepression is the most common psychiatric disorder in patients with multiple sclerosis but the relationship between the two conditions is complex. In this article, the authors discuss the factors that may contribute to depression in patients with multiple sclerosis, the ways in which each condition may affect the other and the treatment options available. Copyright © 2010 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=4261283 Mon, 01 Nov 2010 00:00:00 +0100 4261283 http://www.medworm.com/index.php?rid=4261282&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.176 AbstractIncreased demands but reduced resources. Illusory targets and unrealistic milestones. Short‐term expedience rather than long‐term vision. Such is the pressured environment for those working within mental health services in the UK in 2010. How good it is, therefore, to find something to celebrate. Clearly, the Latest Advances in Psychiatry symposia cannot reverse these fundamental problems, but they do offer some respite: a chance to address personal Continuing Professional Development (CPD) objectives, to listen to experts at the top of their field, to catch up with colleagues, and to cherish the brief time away from the hurly‐burly of psychiatric practice. Copyright © 2010 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=4261282 Mon, 01 Nov 2010 00:00:00 +0100 4261282 http://www.medworm.com/index.php?rid=4042459&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.175 Abstract (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=4042459 Tue, 31 Aug 2010 23:00:00 +0100 4042459 http://www.medworm.com/index.php?rid=4042458&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.174 Abstract (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=4042458 Tue, 31 Aug 2010 23:00:00 +0100 4042458 http://www.medworm.com/index.php?rid=4042457&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.173 Abstract (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=4042457 Tue, 31 Aug 2010 23:00:00 +0100 4042457 http://www.medworm.com/index.php?rid=4042456&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.172 Abstract (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=4042456 Tue, 31 Aug 2010 23:00:00 +0100 4042456 http://www.medworm.com/index.php?rid=4042455&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.171 Abstract (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=4042455 Tue, 31 Aug 2010 23:00:00 +0100 4042455 http://www.medworm.com/index.php?rid=3926504&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.170 Abstract (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=3926504 Wed, 30 Jun 2010 23:00:00 +0100 3926504 http://www.medworm.com/index.php?rid=3926503&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.169 Abstract (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=3926503 Wed, 30 Jun 2010 23:00:00 +0100 3926503 http://www.medworm.com/index.php?rid=3926502&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.168 Abstract (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=3926502 Wed, 30 Jun 2010 23:00:00 +0100 3926502 http://www.medworm.com/index.php?rid=3926501&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.167 Abstract (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=3926501 Wed, 30 Jun 2010 23:00:00 +0100 3926501 http://www.medworm.com/index.php?rid=3926500&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.166 Abstract (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=3926500 Wed, 30 Jun 2010 23:00:00 +0100 3926500 http://www.medworm.com/index.php?rid=3926499&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.165 Abstract (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=3926499 Wed, 30 Jun 2010 23:00:00 +0100 3926499 http://www.medworm.com/index.php?rid=3642790&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.164 Antidepressant use and learning disabilityAnalysis of the records of 221 adults attending the Welsh Centre for Learning Disability in Cardiff identified 241 episodes of treatment with an antidepressant within the past five years (The Psychiatrist 2010;34:123-6).Antidepressants were prescribed for depression in 61 per cent of cases, for generalised anxiety disorder in 10 per cent and obsessive-compulsive disorder in 10 per cent. SSRIs accounted for over three-quarters of agents prescribed, with citalopram the most popular (43 per cent). Other antidepressants were mirtazapine (8 per cent), trazodone (6 per cent), serotonin-noradrenaline reuptake inhibitors (SNRIs) (4 per cent) and tricyclic antidepressants (5 per cent). In almost 80 per cent of episodes, antidepressants were coprescribed wit... Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=3642790 Tue, 08 Jun 2010 23:00:00 +0100 3642790 http://www.medworm.com/index.php?rid=3642789&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.163 The use of computer software programmes to deliver cognitive behavioural therapy to people with mental health disorders is becoming increasingly popular. Here the authors describe what conditions computerised cognitive behavioural therapy may be useful for, discuss its advantages and disadvantages and outline the current NICE guidance on its use. Copyright © 2010 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=3642789 Tue, 08 Jun 2010 23:00:00 +0100 3642789 http://www.medworm.com/index.php?rid=3642788&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.162 Over the past year, Progress in Neurology and Psychiatry has been running a series of articles on the major psychiatric drug groups, produced in association with the College of Mental Health Pharmacy. In the final article in the series, Michele Sie describes the main types of sleep disorder and their features, and provides an overview of their treatment. Copyright © 2010 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=3642788 Tue, 08 Jun 2010 23:00:00 +0100 3642788 http://www.medworm.com/index.php?rid=3642787&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.161 No Abstract. (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=3642787 Fri, 30 Apr 2010 23:00:00 +0100 3642787 http://www.medworm.com/index.php?rid=3478608&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.160 Phase III trials demonstrate promise for new oral treatmentsNovartis's fingolimod, a sphingosine-1-phosphate receptor modulator that reduces lymphocyte infiltration into the CNS and may also have neuroprotective activity, has been compared with placebo (New Engl J Med 2010;362:387-401) and interferon beta-1a (New Engl J Med 2010;362:402-15) in patients with relapsing-remitting MS and milder disability (Expanded Disability Status Scale (EDSS) score 0-5.5) an average of seven to eight years after diagnosis.The two-year placebo-controlled trial included 1272 patients aged 18-55 years with at least one relapse in the previous year, or two in the previous two years, and a mean EDSS of 2.3-2.5. Two dosages of fingolimod were included (0.5mg and 1.25mg daily); both were significantly superior to ... Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=3478608 Thu, 15 Apr 2010 23:00:00 +0100 3478608 http://www.medworm.com/index.php?rid=3478607&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.159 It is recognised that antiepileptic drug choice is driven by the desire for seizure control, but patient quality of life and consideration of other factors are also important for the treatment of the individual as a whole. In this expert panel discussion, three specialists discuss the benefits and potential for improved outcomes of a patient-centred approach to epilepsy management. Copyright © 2010 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=3478607 Thu, 15 Apr 2010 23:00:00 +0100 3478607 http://www.medworm.com/index.php?rid=3478606&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.158 In Pregnancy is a series of reviews focusing on the management of women with psychiatric and neurological conditions during pregnancy. In this article, Dr Micali discusses how pregnancy may affect women with eating disorders, as well as the effect of eating disorders on pregnancy outcomes. Copyright © 2010 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=3478606 Thu, 15 Apr 2010 23:00:00 +0100 3478606 http://www.medworm.com/index.php?rid=3478605&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.157 No Abstract. (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=3478605 Thu, 15 Apr 2010 23:00:00 +0100 3478605 http://www.medworm.com/index.php?rid=3478604&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.156 Patients prescribed clozapine have associated physical health risks because of both use of the drug itself and their underlying mental illness. It is therefore important that primary and secondary care work closely together to optimise patient care. Here, the authors describe their audit of patients prescribed clozapine in secondary care to identify whether they were registered on their GP practice's severe mental illness register and whether the practice had a record that they were taking clozapine. Copyright © 2010 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=3478604 Thu, 15 Apr 2010 23:00:00 +0100 3478604 http://www.medworm.com/index.php?rid=3478603&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.155 The Crisis Resolution and Home Treatment (CRHT) team's role in acute mental healthcare services for working age adults is well established throughout England, but this is less so for older adults despite government policy and initiatives promoting equality of care. The authors highlight the need to extend this care model to older people's mental healthcare and suggest some possible ways of achieving this. Copyright © 2010 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=3478603 Mon, 01 Mar 2010 00:00:00 +0100 3478603 http://www.medworm.com/index.php?rid=3277891&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.154 Migrainous vertigoMigraine and vertigo may occur together but there is little evidence to show whether drug treatment is effective. Investigators from Turkey have now evaluated prophylaxis with topiramate 50 or 100mg daily in 30 women meeting published criteria for 'migrainous vertigo' in whom Meniere's disease had been excluded (Headache 2010;50:77-84).Over 24 weeks, topiramate reduced the mean frequency of vertigo attacks compared with pretreatment levels from 8.1 to 2.3 per month and headache frequency from 5.2 to 2.0 per month; it also reduced the severity of both vertigo and headache. There were no significant differences between doses. Adverse effects were common (paraesthesias, fatigue, impaired memory and concentration and decreased appetite), leading four women to discontinue trea... Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=3277891 Tue, 16 Feb 2010 00:00:00 +0100 3277891 http://www.medworm.com/index.php?rid=3277890&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.153 Although more quality research is required to inform clinical practice, serotonin-noradrenaline reuptake inhibitor - noradrenaline and specific serotonergic antidepressant (SNRI-NaSSA) combination therapy shows promise for treatment-resistant depression. Here, Dr Pandarakalam discusses the rationale behind the use of this combination and some of the evidence gained so far for its efficacy. Copyright © 2010 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=3277890 Tue, 16 Feb 2010 00:00:00 +0100 3277890 http://www.medworm.com/index.php?rid=3277889&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.152 New Horizons: a shared vision for mental health1 is a cross-government programme of action launched in December 2009, with the aim of improving the mental well-being of people in England as well as the quality of mental health care. Here, Steve Titmarsh reports on the reactions of leading mental health charities Mind and Rethink to the launch of New Horizons. Copyright © 2010 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=3277889 Tue, 16 Feb 2010 00:00:00 +0100 3277889 http://www.medworm.com/index.php?rid=3277888&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.151 Progress in Neurology and Psychiatry is running a series of articles on the major psychiatric drug groups, produced in association with the College of Mental Health Pharmacists. In this article, Delia Bishara discusses the use of cognitive enhancers in Alzheimer's disease (AD) and other dementias and provides an overview of new treatments in development. Copyright © 2010 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=3277888 Tue, 16 Feb 2010 00:00:00 +0100 3277888 http://www.medworm.com/index.php?rid=3277887&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.150 The 2004 NICE technology appraisal defined new standards for the use of newer antiepileptic drugs (AEDs) in children.The aim of this audit was to identify the level of compliance with the NICE guidelines in an epilepsy clinic at a district general hospital in East Kent.The reason why a child was started on a particular AED, the efficacy of the drug of choice and whether the child had appropriate specialist reviews were investigated. Copyright © 2010 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=3277887 Tue, 16 Feb 2010 00:00:00 +0100 3277887 http://www.medworm.com/index.php?rid=3277886&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.149 Most of us welcome the new direction of travel for mental health advocated by the recently published cross-government action programme New Horizons,1 the 2008 Lord Darzi report High Quality Care for All2 plus the 2007 personalisation agenda Putting People First.3. Copyright © 2010 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=3277886 Fri, 01 Jan 2010 00:00:00 +0100 3277886 http://www.medworm.com/index.php?rid=3081119&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.148 Treatment options for panic disorderSome patients with panic disorder do not respond to first-line treatment with an SSRI and, say US investigators, there is a lack of evidence on which to base subsequent treatment choices (J Clin Psychiatry 2009; October 6 doi:10.4088/JCP.08m04485blu).Their three-phase trial involved initial open-label treatment with sertraline (up to 100mg daily) or escitalopram (up to 15mg daily) for six weeks. Of 39 patients, 20 per cent achieved remission; the others were then randomised to continue with their initial treatment plus placebo or to receive an increased dose of SSRI (up to 200mg daily sertraline or up to 30mg daily escitalopram). After a further six weeks, symptom scores improved in both groups but there was no significant increase in remission rate with... Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=3081119 Fri, 11 Dec 2009 00:00:00 +0100 3081119 http://www.medworm.com/index.php?rid=3081118&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.147 Delirium is often underdetected or misdiagnosed within the hospital setting. Here, the authors present the results of their study to assess whether a simple educational programme delivered to nursing staff within their District General Hospital can improve the rate of detection of delirium. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=3081118 Fri, 11 Dec 2009 00:00:00 +0100 3081118 http://www.medworm.com/index.php?rid=3081117&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.146 The lecture 'Sleep Disorders - an Update for Psychiatrists' was given by Professor Gregory Stores at the eighth Latest Advances in Psychiatry Symposium in London in March. Professor Stores discussed the fact that sleep disorders can often be misinterpreted as psychiatric disorders, and in this article, he provides more information on this often-neglected topic. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=3081117 Fri, 11 Dec 2009 00:00:00 +0100 3081117 http://www.medworm.com/index.php?rid=3081116&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.145 Identifying and treating depression in adults with chronic physical health problems (including neurological disorders) is highlighted in a new clinical guideline from the National Institute for Health and Clinical Excellence (NICE).1 The new guideline is linked with an updated version of NICE's depression clinical guideline.2 SteveTitmarsh reports from a Press briefing held in London to announce the new guidelines. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=3081116 Fri, 11 Dec 2009 00:00:00 +0100 3081116 http://www.medworm.com/index.php?rid=3081115&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.144 Progress in Neurology and Psychiatry is running a series of articles on the major psychiatric drug groups, produced in association with the College of Mental Health Pharmacists. In this article, Stephen Bleakley provides an overview of the main types of anxiety disorder and the efficacy and side-effects of the drugs recommended for the treatment of these disorders. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=3081115 Fri, 11 Dec 2009 00:00:00 +0100 3081115 http://www.medworm.com/index.php?rid=3081114&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.143 The Parkinson's Disease Society's 6th Spring Conference for Researchers was held in London in May, entitled 'Parkinson's Disease:The Pieces of the Puzzle'. Here, Dr Lynn Bedford, Parkinson's Disease Society Senior Research Fellow, reports on some of the highlights of the conference, including the latest genetic research, the importance of pre-motor symptoms and the therapeutic potential of the peptide exendin-4, found in the saliva of a poisonous lizard. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=3081114 Fri, 11 Dec 2009 00:00:00 +0100 3081114 http://www.medworm.com/index.php?rid=3081113&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.142 In Pregnancy is a series of reviews focusing on the management of women with psychiatric and neurological conditions during pregnancy. In this article, Dr Brookings and Dr Lee describe how pregnancy can affect the course of multiple sclerosis (MS),discuss the safety of MS therapies and highlight other management issues to consider during pregnancy and postpartum. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=3081113 Fri, 11 Dec 2009 00:00:00 +0100 3081113 http://www.medworm.com/index.php?rid=3081112&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.141 In this article, Dr de Silva argues that understanding bias and the application of appropriate safegards to avoid it mark out true professionalism and leadership within medical practice, and describes how this applies within the field of psychiatry in particular. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=3081112 Sun, 01 Nov 2009 00:00:00 +0100 3081112 http://www.medworm.com/index.php?rid=2936731&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.140 Lithium and cognition: meta-analysisBipolar disorder has been associated with cognitive impairment but it has been unclear what the contribution of medication may be. US investigators tackled the problem with a metaanalysis. They looked at 12 double-blind trials (from a possible 586 publications) in 539 healthy volunteers or patients (n=326) reporting the cognitive effects of lithium (J Clin Psychiatry 2009;doi:10.4088/ JCP.08r04972). Among patients, the mean duration of lithium use was 3.9 years and the mean serum concentration was 0.82mEq per litre. In volunteers, mean lithium exposure was 2.5 weeks and the mean serum level was 0.78mEq per litre.Lithium was associated with statistically significant but 'mild' impairment of creativity and immediate verbal learning and memory. There were n... Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=2936731 Wed, 28 Oct 2009 00:00:00 +0100 2936731 http://www.medworm.com/index.php?rid=2936730&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.139 The pharmacokinetic profile of risperidone long-acting injection (RLAI) has lead to specific recommendations for its treatment initiation. A team of Mental Health Nurse Advisers conducted this audit in a cohort of 1647 patients from 32 centres in the UK to assess to what extent treatment with RLAI is initiated according to these recommendations and how this affects treatment adherence. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=2936730 Wed, 28 Oct 2009 00:00:00 +0100 2936730 http://www.medworm.com/index.php?rid=2936729&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.138 The Keynote Lecture at the eighth LatestAdvances in Psychiatry Symposium, held in London in March, was given by Professor Gerald Russell, Emeritus Professor of Psychiatry at the Institute of Psychiatry in London. He noted that eating disorders are sometimes associated with a markedly excess mortality. A high crude mortality rate (2.2 per cent per annum) was recorded in a UK series of compulsorily treated anorexia patients, in keeping with these patients, dogged resistance to treatment.1 While bulimia nervosa may respond to fluoxetine, there is no effective pharmacological treatment for anorexia nervosa. Nevertheless,psychological treatments may improve outcomes in both anorexia and bulimia nervosa, although NICE has only grudgingly recognised their efficacy. Medical writer, Mark Greener, r... Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=2936729 Wed, 28 Oct 2009 00:00:00 +0100 2936729 http://www.medworm.com/index.php?rid=2936728&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.137 In Pregnancy is a series of reviews focusing on the management of women with psychiatric and neurological conditions during pregnancy. In this article, Dr MacGregor discusses the effect of pregnancy on migraine and the treatment choices available to women during pregnancy and lactation. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=2936728 Wed, 28 Oct 2009 00:00:00 +0100 2936728 http://www.medworm.com/index.php?rid=2936727&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.136 In the April 2008 issue of Progress,we featured an article describing a new technique for improving arm movement following stroke developed at the University of Southampton.The technique involves the use of a robotic workstation delivering precisely controlled electrical stimulation mediated by iterative learning control to improve task performance.Here,the scientists who developed the system discuss the promising results of their pilot clinical study using this technique. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=2936727 Wed, 28 Oct 2009 00:00:00 +0100 2936727 http://www.medworm.com/index.php?rid=2936726&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.135 Early and aggressive treatment of rheumatoid arthritis (RA) is now regarded as best practice to limit irreversible joint damage. However, in the case of relapsing remitting multiple sclerosis (RRMS), current guidelines recommend that disease modifying therapy should only be initiated in patients with evidence of actively progressing disease. Here, the authors present the key findings of the Programme Identifying and Observing Novel Therapy Adoption in Chronic Diseases (PIONEER) study to examine the reasons for these different management approaches. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=2936726 Wed, 28 Oct 2009 00:00:00 +0100 2936726 http://www.medworm.com/index.php?rid=2936725&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.134 Progress is pleased to bring readers key articles from the charity Primary Care Mental Health and Education (Primhe), which covers issues relating particularly to mental health in the primary care setting. On our website, , this month Dr Robinson, a GP with a special interest in mental health,describes how an encounter with a patient led her to re-evaluate her approach to patients with mental health issues. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=2936725 Wed, 28 Oct 2009 00:00:00 +0100 2936725 http://www.medworm.com/index.php?rid=2936724&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.133 When something does not work, we have a tendency to believe we just need to do more of the same, ie try harder. Mental health treatment is an example of this. When our patients fail to heed what we are saying, we often blame them for not listening, instead of asking why they are not compliant to our best intentions. The reality is that, for our patients and society in general, we lack credibility, as there is a general belief that treatments for mental health problems do not work. We reinforce this by maintaining people in secondary care services, rather than actively working to discharge them back into primary care services and the community. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=2936724 Tue, 01 Sep 2009 00:00:00 +0100 2936724 http://www.medworm.com/index.php?rid=2680236&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.132 Antidepressant RCTs meaningful?The Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trial of sequenced anti-depressant therapy recruited a broad population of patients representative of outpatients with depression seeking treatment. By contrast, most randomised controlled trials (RCTs) have more restrictive eligibility criteria. STAR*D investigators have now used their data to assess the impact of this aspect of trial design (Am J Psychiatry 2009;166:599-67).They divided 2855 STAR*D participants into a group meeting standard eligibility criteria based on HAM-D score >19, lack of comorbidity and duration of current episode less than 24 months (22 per cent) and a second group who did not meet these criteria.Those meeting standard criteria were more likely to be seen in special... Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=2680236 Thu, 06 Aug 2009 23:00:00 +0100 2680236 http://www.medworm.com/index.php?rid=2680235&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.131 In the context of a project to benchmark anti-dementia drug prescribing practice against standards derived from evidence-based guidelines, the authors sought to estimate the proportion of people with dementia who were receiving treatment with an anti-dementia drug and whether this varied across Primary Care Trust (PCT) populations.They also explored the relative proportion of prescriptions for each anti-dementia drug, and the source of these prescriptions - GPs,Mental HealthTrusts or acuteTrusts. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=2680235 Thu, 06 Aug 2009 23:00:00 +0100 2680235 http://www.medworm.com/index.php?rid=2680234&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.130 In a Pfizer-sponsored satellite meeting at the Latest Advances in Psychiatry Symposium in London in March, Dr David Baldwin, Reader in Psychiatry and Honorary Consultant Psychiatrist at University of Southampton, reviewed the drug treatment of generalised anxiety disorder. Medical writer, Mark Greener, reports. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=2680234 Thu, 06 Aug 2009 23:00:00 +0100 2680234 http://www.medworm.com/index.php?rid=2680233&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.129 No Abstract. (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=2680233 Thu, 06 Aug 2009 23:00:00 +0100 2680233 http://www.medworm.com/index.php?rid=2680232&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.128 In the fourth of this series on the major psychiatric drug groups, Caroline Parker discusses the use of drug treatments in the management of attention deficit hyperactivity disorder (ADHD), including their indications, efficacy, adverse effects and recommended dosing regimens. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=2680232 Thu, 06 Aug 2009 23:00:00 +0100 2680232 http://www.medworm.com/index.php?rid=2680231&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.127 Sensory processing disorder (SPD) is a term advocated by some occupational therapists to describe a range of problems that might be amenable to particular treatment strategies, and has mainly been applied within the fields of paediatrics and learning disability.In this article,the authors investigate whether there could be a common ground between borderline personality disorder (BPD) and SPD and describe an extension of the treatment strategies for SPD to those with BPD in their acute inpatient unit. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=2680231 Thu, 06 Aug 2009 23:00:00 +0100 2680231 http://www.medworm.com/index.php?rid=2680230&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.126 No Abstract. (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=2680230 Tue, 30 Jun 2009 23:00:00 +0100 2680230 http://www.medworm.com/index.php?rid=2491881&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.125 Safety of ramelteonThere is great interest in the role of melatonin agonists as treatments for insomnia. Ramelteon is already available in the USA, where it is used to reduce sleep latency associated with primary insomnia. Licensing in Europe has been delayed after the European Medicines Agency questioned its efficacy. Two studies now report on the safety of ramelteon over one year.The first study enrolled 1213 adults taking ramelteon 16mg (18-64 year age group) or 8mg (over-65 years) and were considered compliant if they took it at least three nights per week (J Clin Psychiatry 2009; pii:ej07m03834). In the younger group taking 16mg, 51 per cent discontinued treatment within six months and 62 per cent within 48 weeks; in the older group taking 8mg, the figures were 49 per cent and 58 per ... Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=2491881 Tue, 23 Jun 2009 23:00:00 +0100 2491881 http://www.medworm.com/index.php?rid=2491880&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.124 IIn the third of this series on the major psychiatric drug groups, the author discusses the choice and use of mood stabilisers in the management of bipolar affective disorder. Pharmacology, interactions and side-effects, as well as information to give to patients are described. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=2491880 Tue, 23 Jun 2009 23:00:00 +0100 2491880 http://www.medworm.com/index.php?rid=2491879&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.123 In a Servier-sponsored satellite meeting at the Latest Advances in Psychiatry Symposium in London in March, Professor Bill Deakin, Professor of Psychiatry and Director of the Neuroscience and Psychiatry Unit at the University of Manchester, reviewed a recent addition to the antidepressant armamentarium - agomelatine - a drug that that shows a unique pharmacological profile. Medical writer, Mark Greener, reports. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=2491879 Tue, 23 Jun 2009 23:00:00 +0100 2491879 http://www.medworm.com/index.php?rid=2491878&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.122 Progress: Advancing Parkinson's Research, the Parkinson's Disease Society research conference dedicated to showcasing the work of young Parkinson's disease researchers, was held in York in November 2008, attracting nearly 200 delegates. Neil Archibald, Parkinson's Disease Society Research Fellow, reports on some of the highlights of the conference, including stem cell and gene therapy research, the role of Lewy bodies in dementia and the use of deep brain stimulation in the treatment of Parkinson's disease. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=2491878 Tue, 23 Jun 2009 23:00:00 +0100 2491878 http://www.medworm.com/index.php?rid=2491877&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.121 Cluster headache is an excruciatingly painful primary headache syndrome with rapid onset attacks that are relatively short, typically up to three hours. Management strategies involve avoidance of possible triggers to attacks, such as alcohol and naps, and pharmacological treatments aimed at either quickly aborting acute attacks, or preventive therapies to suppress the attacks entirely, or reduce their frequency, severity or duration. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=2491877 Tue, 23 Jun 2009 23:00:00 +0100 2491877 http://www.medworm.com/index.php?rid=2491876&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.120 Whether Parkinson's disease (PD) increases mortality remains something of a moot point. Some studies suggest that mortality among PD patients is more than three'fold higher than the death rates in the general population. Other studies suggest there's no difference. Changes in mortality over time are also inconsistent.However,some researchers detect a decline in mortality beginning during the 1970s,around the time that levodopa entered clinical practice.1 Now a new study2 that followed PD patients for 20 years helps clarify this sometimes controversial relationship. Freelance medical writer, Mark Greener, reports. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=2491876 Tue, 23 Jun 2009 23:00:00 +0100 2491876 http://www.medworm.com/index.php?rid=2491875&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.119 Somatoform disorders, or medically unexplained symptoms, present a significant challenge to the clinician, who needs to establish and reassure the patient that the complaint is not serious, while at the same time try to avoid the symptoms being iatrogenically maintained. Here, Dr Hadler and Dr Poole suggest a practical approach to the management of such disorders. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=2491875 Thu, 30 Apr 2009 23:00:00 +0100 2491875 http://www.medworm.com/index.php?rid=2480327&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.118 'Real life' experience with rivastigmineThe Swedish Alzheimer Treatment Study is a non-blinded investigation of the long-term use of cholinesterase inhibitors for Alzheimer's disease in routine clinical practice (Acta Neurol Scand 2009;119:180-5). In a subgroup of 217 patients with mild to moderate disease (mean baseline Mini-Mental State Examination (MMSE) score 22.9, Alzheimer's Disease Assessment Scale - cognitive sub-scale (ADAS-cog) 18.5), treatment with rivastigmine was associated with an initial increase in MMSE score at two months, followed by a steady decline with a final difference of 1.84 points below baseline overall at 24 months. There was a corresponding worsening of ADAS-cog scores. However, MMSE and ADAS-cog scores were stable or improved in approximately 40 per cent of pat... Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=2480327 Fri, 03 Apr 2009 04:00:00 +0100 2480327 http://www.medworm.com/index.php?rid=2480326&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.117 Medicine taking behaviour in depression is erratic, resulting in poor outcomes and increased cost to society.Indeed,the illness itself has been shown to be a risk factor for poor adherence.The first article of this two-part series (Progress issue 1, 2009) explored poor adherence with antidepressant treatment and effect on outcome. In this article treatment variables that may affect adherence are explored alongside some of the interventions that have been proposed to improve medicine taking behaviour in patients with depression.The effect these had on outcome is examined and recommendations, based on current evidence, are made as to what should be done to improve adherence in depression. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=2480326 Fri, 03 Apr 2009 04:00:00 +0100 2480326 http://www.medworm.com/index.php?rid=2480325&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.116 In the second of a new series of articles on the major psychiatric drug groups, produced in association with the College of Mental Health Pharmacists, the author discusses the use of antipsychotics through a review of the clinical literature. Pharmacology, interactions and side-effects as well as drug choice and information to give to patients are discussed. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=2480325 Fri, 03 Apr 2009 04:00:00 +0100 2480325 http://www.medworm.com/index.php?rid=2480324&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.115 Few disorders are as devastating as motor neurone disease (MND). Imagine a healthy and alert mind trapped inside a body that cannot move: that's the reality of MND. Mel Barry, Communications Manager at the MND Association, discusses how the association is helping to support and improve the lives of people affected by the illness. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=2480324 Fri, 03 Apr 2009 04:00:00 +0100 2480324 http://www.medworm.com/index.php?rid=2480323&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.114 Atomoxetine is a non-stimulant drug licensed for use in the treatment of attention deficit-hyperactivity disorder (ADHD).Dr Banerjee describes a study that was carried out over a two-year period in the three ADHD clinics in East Kent Hospitals NHS Trust to evaluate the current practice on the use of atomoxetine in ADHD in children and adolescents. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=2480323 Fri, 03 Apr 2009 04:00:00 +0100 2480323 http://www.medworm.com/index.php?rid=2480322&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.113 In Pregnancy is a series of reviews focusing on the management of women with psychiatric and neurological conditions during pregnancy. In this article, Dr Osborne and Dr O'Keane discuss the risks discuss the risk factors for the development of depression during pregnancy, its possible impact on the developing foetus and the current recommended management. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=2480322 Fri, 03 Apr 2009 04:00:00 +0100 2480322 http://www.medworm.com/index.php?rid=2480321&cid=s_38756_25_f&fid=38756&url=http%3A%2F%2Fdx.doi.org%2F10.1002%252Fpnp.112 I welcome the Department of Health's National Dementia strategy.1 It rightly encourages early diagnosis in dementia and potetially the identification of a huge number of patients currently not recognised as having dementia. It should, by doing so, bring to attention the severe lack of resources for dementia patients and their carers and start to force the introduction of adequate services for a very needy and under-resourced group. Copyright © 2009 Wiley Interface Ltd (Source: Progress in Neurology and Psychiatry) Progress in Neurology and Psychiatry journals http://www.medworm.com/rss/comments.php?id=2480321 Sun, 01 Mar 2009 05:00:00 +0100 2480321