MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Psychiatry and Clinical Neurosciences' source. Tue, 07 Feb 2012 07:05:47 +0100 http://www.medworm.com/index.php?rid=5657836&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02292.x Conclusions:  Our findings suggest that hikikomori cases are more likely to occur in families where the parents have high levels of education. Maternal panic disorder may be another risk factor for children to develop hikikomori. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5657836 Thu, 02 Feb 2012 05:00:00 +0100 5657836 http://www.medworm.com/index.php?rid=5657835&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02301.x Loss of antipsychotic efficacy (tachyphylaxis), possibly linked to an increase in D2 receptor number and sensitivity, is a significant impediment to treatment in chronic schizophrenia patients. Animal studies, however, suggest that aripiprazole may be free from tachyphylaxis. The aim of the present study was to investigate this hypothesis. In this preliminary study, aripiprazole‐treated patients were retrospectively investigated for the presence or absence of tachyphylaxis. Clinical Global Impression‐Improvement (CGI‐I) scores did not significantly change and there was no significant association of CGI scores with fixed dose duration. This suggests that aripiprazole may be free from tachyphylaxis. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5657835 Thu, 02 Feb 2012 05:00:00 +0100 5657835 http://www.medworm.com/index.php?rid=5657834&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02302.x Conclusion:  The right hemisphere appears to be dominant, and there is interhemispheric cooperation in gaze‐triggered reflexive shift of attention. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5657834 Thu, 02 Feb 2012 05:00:00 +0100 5657834 http://www.medworm.com/index.php?rid=5657833&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02303.x The aim of the present study was to investigate, for the first time, the relationship between circadian preference and mood seasonality in adolescents. To this end, 1539 participants (881 female; 658 male) completed the Morningness–Eveningness Questionnaire for Children and Adolescents and the Seasonal Pattern Assessment Questionnaire for Children and Adolescents to determine circadian preference and mood seasonality, respectively. Evening types achieved significantly higher mood seasonality scores than intermediate and morning types, as intermediates did than morning types. Agreeing with previous studies on young adults and adults, the present data indicate a significant relationship between eveningness and higher mood seasonality in adolescents. (Source: Psychiatry and Clinical Neurosc... Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5657833 Wed, 01 Feb 2012 05:00:00 +0100 5657833 http://www.medworm.com/index.php?rid=5605587&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02288.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5605587 Thu, 19 Jan 2012 12:22:56 +0100 5605587 http://www.medworm.com/index.php?rid=5605586&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02294.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5605586 Thu, 19 Jan 2012 12:22:54 +0100 5605586 http://www.medworm.com/index.php?rid=5605585&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02298.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5605585 Thu, 19 Jan 2012 12:22:53 +0100 5605585 http://www.medworm.com/index.php?rid=5605584&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02295.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5605584 Thu, 19 Jan 2012 12:22:51 +0100 5605584 http://www.medworm.com/index.php?rid=5605583&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02297.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5605583 Thu, 19 Jan 2012 12:22:49 +0100 5605583 http://www.medworm.com/index.php?rid=5605582&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02283.x Reminiscence therapy workshops for health‐care professionals (total, n = 105: four trainees in their 20, seven in their 30s, 13 in their 40s, 30 in their 50s, 41 in their 60, five in their 70s, one in their 80s, and four of unknown age) were held, and group work with reminiscence therapy was provided to local residents (total, n = 151; mean age, 73.6 ± 10.6 years). Comparison of pre‐ and post‐workshop questionnaires showed that rates of interest and understanding of trainees increased after the workshop. Concerning group work, 89.2% of the participants felt that reminiscence therapy would prove helpful in their life. Reminiscence therapy may be useful in improving mental health in local residents. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5605582 Thu, 19 Jan 2012 12:22:48 +0100 5605582 http://www.medworm.com/index.php?rid=5605581&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02296.x Conclusions:  The low dosages of amisulpride elevate serum prolactin level in the majority of patients. This finding indicates that the dose‐reduction of amisulpride has little effect to relieve amisulpride‐induced hyperprolactinemia at therapeutic dosages. Clinicians should monitor serum prolactin level even when low dosages of amisulpride are administered. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5605581 Thu, 19 Jan 2012 12:22:46 +0100 5605581 http://www.medworm.com/index.php?rid=5605580&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02291.x Conclusions:  As age increases, the chances of developing dementia increase. Dementia, contrarily, is not selective between genders. The likelihood of developing dementia increases as the stage of disease advances. Further research is required in order to understand underlying mechanisms of dementia in Parkinson's disease. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5605580 Thu, 19 Jan 2012 12:22:45 +0100 5605580 http://www.medworm.com/index.php?rid=5605579&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02289.x Conclusion:  OROS‐MPH treatment at the adequate dosage can achieve higher remission and recovery rates, produce greater functional improvement, and result in better treatment adherence than IR‐MPH treatment. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5605579 Thu, 19 Jan 2012 12:22:43 +0100 5605579 http://www.medworm.com/index.php?rid=5605578&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02287.x Conclusions:  PDD differs from ATPD not only in the duration of the psychotic symptoms, but also in a variety of significant variables. They appear to be two separate entities within a psychotic spectrum. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5605578 Thu, 19 Jan 2012 12:22:42 +0100 5605578 http://www.medworm.com/index.php?rid=5605577&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02293.x Conclusion:  These findings provide evidence of left uncinate fasciculus damage resulting in disrupted communication between orbitofrontal prefrontal areas and temporal areas in deficit schizophrenia patients. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5605577 Thu, 19 Jan 2012 12:22:40 +0100 5605577 http://www.medworm.com/index.php?rid=5605576&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02290.x Conclusion:  PFC dysfunction may exist in PDD. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5605576 Thu, 19 Jan 2012 12:22:38 +0100 5605576 http://www.medworm.com/index.php?rid=5605575&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02282.x Conclusions:  A close and critical examination of the various elements of the undergraduate placement in psychiatry is needed in order to develop an evidence‐based, fully rounded education with an anti‐stigma orientation. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5605575 Thu, 19 Jan 2012 12:22:37 +0100 5605575 http://www.medworm.com/index.php?rid=5605574&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02286.x Conclusions:  Migraine may have a negative impact on the improvement of partial SF‐36 subscales, especially on functional recovery, after acute treatment among outpatients with MDD. Whether additional intervention besides antidepressant treatment for migraine is indicated may need further study. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5605574 Thu, 19 Jan 2012 12:22:35 +0100 5605574 http://www.medworm.com/index.php?rid=5605573&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02304.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5605573 Thu, 19 Jan 2012 12:22:33 +0100 5605573 http://www.medworm.com/index.php?rid=5521701&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02299.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5521701 Thu, 01 Dec 2011 05:00:00 +0100 5521701 http://www.medworm.com/index.php?rid=5521700&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02273.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5521700 Thu, 01 Dec 2011 05:00:00 +0100 5521700 http://www.medworm.com/index.php?rid=5521699&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02276.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5521699 Thu, 01 Dec 2011 05:00:00 +0100 5521699 http://www.medworm.com/index.php?rid=5521698&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02277.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5521698 Thu, 01 Dec 2011 05:00:00 +0100 5521698 http://www.medworm.com/index.php?rid=5521697&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02278.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5521697 Thu, 01 Dec 2011 05:00:00 +0100 5521697 http://www.medworm.com/index.php?rid=5521696&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02279.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5521696 Thu, 01 Dec 2011 05:00:00 +0100 5521696 http://www.medworm.com/index.php?rid=5521695&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02269.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5521695 Thu, 01 Dec 2011 05:00:00 +0100 5521695 http://www.medworm.com/index.php?rid=5521694&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02280.x The objective was to examine effects of active interventions on physician's prescribing of antipsychotic polypharmacy. Prescriptions for patients with schizophrenia at the Centre for Addiction and Mental Health, Canada were collected in 2006 (n = 648) and 2008 (n = 778). During the intervening period, a pharmacist monitored prescriptions with antipsychotic polypharmacy and contacted corresponding prescribers to provide education on risks of polypharmacy. Moreover, educational sessions on polypharmacy were presented to inpatient and outpatient teams. A three‐fold decrease in the prevalence of antipsychotic polypharmacy was observed between 2006 (18.3%) and 2008 (6.6%). Thus, active monitoring of prescriptions with educational interventions could reduce antipsychotic polypharmacy. ... Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5521694 Thu, 01 Dec 2011 05:00:00 +0100 5521694 http://www.medworm.com/index.php?rid=5521693&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02281.x In alphabet‐based language‐speaking patients with schizophrenia, category fluency is disproportionately disturbed as compared with phonological fluency. Deficits in category and phonological fluency observed in Japanese patients, however, were similar. The aim of the present study was to replicate these findings by modifying the task to minimize the influence of lack of motivation and concentration in the patients. Similar deficits were found in both types of fluency in Japanese patients. Patients who speak Japanese have deficits in phonological fluency, compared with patients who speak alphabet‐based languages, suggesting that the pattern of impairment in verbal fluency in schizophrenia is dependent on the specific language system. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5521693 Thu, 01 Dec 2011 05:00:00 +0100 5521693 http://www.medworm.com/index.php?rid=5521692&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02284.x Conclusion:  Hyperhomocysteinemia was more frequent in bipolar I patients independent of C677T polymorphism. Patients had reduced levels of folate, which modulates homocysteine metabolism. Indeed, this finding indicates that folate supplementation may be appropriate for bipolar patients with hyperhomocysteinemia. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5521692 Thu, 01 Dec 2011 05:00:00 +0100 5521692 http://www.medworm.com/index.php?rid=5521691&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02285.x Conclusions:  Parenting bonding styles have an impact on the decoding process and sensitivity when recognizing facial emotions, especially in personality disorder patients. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5521691 Thu, 01 Dec 2011 05:00:00 +0100 5521691 http://www.medworm.com/index.php?rid=5521690&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02256.x Conclusion:  As a life‐changing experience, an intractable disease may influence an increase in self‐transcendence. The results also showed that there was a strong correlation between self‐transcendence and respondents' subjective well‐being. Our results suggest that patients with life‐changing intractable disease can have a high level of self‐transcendence, which may lead them to regain mental well‐being, and increase their psychological health even in situations that cause physical and mental suffering. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5521690 Thu, 01 Dec 2011 05:00:00 +0100 5521690 http://www.medworm.com/index.php?rid=5521689&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02275.x Conclusions:  In a naturalistic setting for the care of depression, it seems that there are no differences in discontinuation times among these three second‐generation antidepressants. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5521689 Thu, 01 Dec 2011 05:00:00 +0100 5521689 http://www.medworm.com/index.php?rid=5521688&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02274.x Conclusion:  SASS‐J showed sufficient reliability and validity, and could be considered a suitable instrument to evaluate social functioning in depressive patients. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5521688 Thu, 01 Dec 2011 05:00:00 +0100 5521688 http://www.medworm.com/index.php?rid=5521687&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02272.x Conclusions:  Without comprehensive postgraduate psychiatric education, the accuracy of recognizing psychiatric symptoms does not improve year by year. Education should focus on common psychiatric problems among medical inpatients, especially those easily misdiagnosed, such as depression and delirium. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5521687 Thu, 01 Dec 2011 05:00:00 +0100 5521687 http://www.medworm.com/index.php?rid=5521686&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02264.x Conclusion:  The evidence suggests that bupropion is superior to placebo and effective for the treatment of ADHD in adults. However, its acceptability and tolerability were not significantly higher than those of placebo. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5521686 Thu, 01 Dec 2011 05:00:00 +0100 5521686 http://www.medworm.com/index.php?rid=5521685&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02268.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5521685 Thu, 01 Dec 2011 05:00:00 +0100 5521685 http://www.medworm.com/index.php?rid=5332707&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02271.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5332707 Sat, 01 Oct 2011 04:00:00 +0100 5332707 http://www.medworm.com/index.php?rid=5332706&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02263.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5332706 Sat, 01 Oct 2011 04:00:00 +0100 5332706 http://www.medworm.com/index.php?rid=5332705&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02261.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5332705 Sat, 01 Oct 2011 04:00:00 +0100 5332705 http://www.medworm.com/index.php?rid=5332704&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02262.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5332704 Sat, 01 Oct 2011 04:00:00 +0100 5332704 http://www.medworm.com/index.php?rid=5332703&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02250.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5332703 Sat, 01 Oct 2011 04:00:00 +0100 5332703 http://www.medworm.com/index.php?rid=5332702&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02259.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5332702 Sat, 01 Oct 2011 04:00:00 +0100 5332702 http://www.medworm.com/index.php?rid=5332701&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02257.x The purpose of the present study was to investigate regional cerebral blood flow (rCBF) changes in a patient with very‐late‐onset schizophrenia‐like psychosis (VLOS) with catatonia. A 64‐year‐old woman developed catatonia after experiencing persecutory delusions. The patient's rCBF was examined using single photon emission computed tomography (SPECT) with easy Z‐score imaging system. Before treatment, hypoperfusion was observed in the striatum and the thalamus, whereas hyperperfusion was observed in the left lateral frontal cortex and the left temporal cortex. After treatment, the disproportions in rCBF disappeared, and hyperperfusion was observed in the motor cortex. Sequential SPECT findings suggest that rCBF abnormalities may be correlated with the symptomatology of catatoni... Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5332701 Sat, 01 Oct 2011 04:00:00 +0100 5332701 http://www.medworm.com/index.php?rid=5332700&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02255.x Non‐clinical schizotypy was found to be related to poorer Wisconsin Card‐Sorting Test (WCST) performance, but the results were inconsistent. Two subgroups, the higher negative–higher positive and the lower negative–lower positive (15 vs 16), were selected from the top and the bottom quartiles of negative and positive scale scores of the Schizotypal Personality Questionnaire (SPQ) completed by 177 healthy volunteers, respectively. The higher negative–higher positive SPQ score subgroup had significantly poorer performance regarding the completed categories of WCST than the lower negative–lower positive SPQ score subgroup. Subjects with higher non‐clinical schizotypy trait showed relatively mild cognitive dysfunction. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5332700 Sat, 01 Oct 2011 04:00:00 +0100 5332700 http://www.medworm.com/index.php?rid=5332699&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02266.x This study examined the psychosocial and psychiatric features of 16 Japanese suicide completers with unmanageable debt compared with 23 suicide completers without such debt at time of death, using a psychological autopsy method. The individuals with unmanageable debt were more likely to have been self‐employed and to have experienced divorce. They were less likely to have engaged in help‐seeking behavior, despite having mental health problems. Our findings suggest that providing comprehensive support and promoting help‐seeking behavior may be important for suicide prevention in middle‐aged men. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5332699 Sat, 01 Oct 2011 04:00:00 +0100 5332699 http://www.medworm.com/index.php?rid=5332698&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02267.x Conclusion:  Although the self‐teaching workbook is a convenient intervention tool that can increase subject awareness and motivation for treatment, it is likely that continuous community‐based support systems are required to prevent relapse. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5332698 Sat, 01 Oct 2011 04:00:00 +0100 5332698 http://www.medworm.com/index.php?rid=5332697&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02258.x Conclusions:  The PNJSS has sufficient reliability and validity as a four‐factor structure containing 22 items, and is valid as a tool for evaluating psychiatric nurse job stressors. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5332697 Sat, 01 Oct 2011 04:00:00 +0100 5332697 http://www.medworm.com/index.php?rid=5332696&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02265.x Conclusions:  The results suggested that CS, including assertive CS and cooperative CS, were improved by the psychiatric training. Increasing self‐esteem and reducing the tendency toward depression and anxiety are considered to be useful for further improving CS. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5332696 Sat, 01 Oct 2011 04:00:00 +0100 5332696 http://www.medworm.com/index.php?rid=5332695&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02260.x Corticosteroids are widely used in modern medicine but can result in troubling psychiatric side‐effects. Physicians and other medical professionals should be aware of the potential for these side‐effects, possible means of prevention, and efficacious treatments. Herein, we review adult case report data published during the past quarter‐century on adverse corticosteroid‐induced psychiatric effects, and present a case of corticosteroid‐induced psychotic depression. PubMed and PsychLit databases were searched using the terms ‘corticosteroids’, ‘steroids’, and the generic names of corticosteroid medications with terms for psychiatric symptoms or syndromes, including psychosis, mania, hypomania, depression, apathy, anxiety, panic, depersonalization, delirium, confusion, halluc... Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5332695 Sat, 01 Oct 2011 04:00:00 +0100 5332695 http://www.medworm.com/index.php?rid=5332694&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02270.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5332694 Sat, 01 Oct 2011 04:00:00 +0100 5332694 http://www.medworm.com/index.php?rid=5205479&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02243.x Conclusion:  Paroxetine CR is efficacious in the acute treatment of MDD and may have the potential benefit of decreasing the incidence of nausea in the early treatment period. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5205479 Tue, 06 Sep 2011 04:00:00 +0100 5205479 http://www.medworm.com/index.php?rid=5205478&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02252.x Conclusions:  Elevated serum cortisol levels in schizophrenic patients might be associated with the role of cortisol in the pathophysiology of schizophrenia. Also, the elevation of serum cortisol levels in first‐degree relatives compared to controls suggests that similar pathophysiological processes might have a role in individuals without any disease symptoms, but with a genetic predisposition for schizophrenia. Elevated serum DHEA‐S levels might be the result of a compensatory response to elevated cortisol levels. Serum cortisol and DHEA‐S levels may be used as a biological marker for the diagnosis of schizophrenia; however, further studies with larger sample sizes are warranted to support this finding. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5205478 Mon, 01 Aug 2011 04:00:00 +0100 5205478 http://www.medworm.com/index.php?rid=5158095&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02232.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5158095 Sun, 31 Jul 2011 23:00:00 +0100 5158095 http://www.medworm.com/index.php?rid=5158094&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02242.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5158094 Sun, 31 Jul 2011 23:00:00 +0100 5158094 http://www.medworm.com/index.php?rid=5158093&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02238.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5158093 Sun, 31 Jul 2011 23:00:00 +0100 5158093 http://www.medworm.com/index.php?rid=5158092&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02230.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5158092 Sun, 31 Jul 2011 23:00:00 +0100 5158092 http://www.medworm.com/index.php?rid=5158090&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02234.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5158090 Sun, 31 Jul 2011 23:00:00 +0100 5158090 http://www.medworm.com/index.php?rid=5158089&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02245.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5158089 Sun, 31 Jul 2011 23:00:00 +0100 5158089 http://www.medworm.com/index.php?rid=5158088&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02248.x The present study sought to determine whether the co‐occurrence of problem drinking heightens suicide risk in individuals with depression in Japan, using a sample of 784 outpatients (287 men and 497 women) with depressive disorder. Female subjects with at least a moderate problem drinking showed significantly more severe depression and suicidality than those without, but no such difference was identified in men. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5158088 Sun, 31 Jul 2011 23:00:00 +0100 5158088 http://www.medworm.com/index.php?rid=5158087&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02244.x In this study, we examined clinical and demographic variables that could impact the plasma substance P level, which is a useful predictive biomarker of aspiration. Thirty‐four patients were included (mean age ± SD: 70.9 ± 10.8 years). A greater number of cigarettes/day and a higher antipsychotic dosage were found to be associated with a lower plasma substance P level, while age showed a trend‐level effect. This finding suggests the need for intensive observation for prevention of aspiration pneumonia in heavy smokers who are receiving a higher antipsychotic dose in this senior population. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5158087 Sun, 31 Jul 2011 23:00:00 +0100 5158087 http://www.medworm.com/index.php?rid=5158086&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02241.x Conclusions:  Serotonergic antidepressants may counteract a procoagulant effect of anxiety and/or depression in anxiety patients. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5158086 Sun, 31 Jul 2011 23:00:00 +0100 5158086 http://www.medworm.com/index.php?rid=5158085&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02235.x Conclusion:  These findings obtained from newly hospitalized major depression patients support the previous notion that pain interference, depression severity, and early improvement can be the predictors for remission. Patients with high pain interference, a greater depression severity or a less early improvement are likely to require aggressive treatment early. These data require confirmation and extension to outpatients and other antidepressants. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5158085 Sun, 31 Jul 2011 23:00:00 +0100 5158085 http://www.medworm.com/index.php?rid=5158084&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02231.x Conclusion:  During the treatment of dysthymia with antidepressants in the SSRI group, tachyphylaxis/tolerance might be observed in a relatively in high proportion of cases. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5158084 Sun, 31 Jul 2011 23:00:00 +0100 5158084 http://www.medworm.com/index.php?rid=5158083&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02251.x Conclusions:  Most patients who were transferred to another hospital were readmitted within 3 months. Some women were readmitted in the late stage. They had relatively high cognitive and physical functions and most of their caregivers had care distress. The causes of readmission were not due to a decline in cognitive function. It is important to prevent complications in dementia patients and to establish a caregiving system for dementia patients that decreases the burden on caregivers in order to reduce the rate of readmission. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5158083 Sun, 31 Jul 2011 23:00:00 +0100 5158083 http://www.medworm.com/index.php?rid=5158082&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02229.x Conclusion:  OFC sulcogyral pattern is altered in SZ‐M but not in SZ‐F, possibly reflecting gender differences in early neurodevelopment. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5158082 Sun, 31 Jul 2011 23:00:00 +0100 5158082 http://www.medworm.com/index.php?rid=5158081&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02246.x Conclusions:  The majority of community‐screened individuals with schizophrenia failed to achieve complete remission at the 6‐year follow up. These results suggest that strategies promoting mental health service utilization among individuals with schizophrenia are essential in Bali. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5158081 Sun, 31 Jul 2011 23:00:00 +0100 5158081 http://www.medworm.com/index.php?rid=5158080&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02249.x Conclusion:  Quality of life and the length of the hospital stay significantly contributed to forward‐looking factors of successful aging. Avoiding long hospitalization periods for patients with schizophrenia may lead to more active preparing behavior, but the improvement of quality of life may not be a sufficient condition. As schizophrenia patients have an optimistic attitude and insufficient preparing behavior, support to prepare such individuals for old age is required as part of community‐based psychiatric care strategies. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5158080 Sun, 31 Jul 2011 23:00:00 +0100 5158080 http://www.medworm.com/index.php?rid=5158079&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02233.x Conclusions:  Suggested methods yielded an otherwise undetectable link between physiology and current PTSD. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5158079 Sun, 31 Jul 2011 23:00:00 +0100 5158079 http://www.medworm.com/index.php?rid=5158078&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02237.x Conclusion:  The societal costs caused by depression in Japan are enormous, as in other developed countries. Low morbidity costs and extremely high mortality costs are characteristic in Japan. Effective interventions for preventing suicide could reduce the societal costs of depression. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5158078 Sun, 31 Jul 2011 23:00:00 +0100 5158078 http://www.medworm.com/index.php?rid=5158077&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02236.x Conclusion:  The screening performance of the Japanese versions of K6 and K10 was comparable with that of CES‐D, and better than that of DDS. K6/K10, particularly K6, might have an advantage, even over the CES‐D, because of its similar screening performance and better acceptability. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5158077 Sun, 31 Jul 2011 23:00:00 +0100 5158077 http://www.medworm.com/index.php?rid=5158076&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02247.x Conclusions:  Episodic course appears to be typical of OCD with BD. Bipolarity has a pathoplastic effect on OCD and it is possible that some forms of OCD and BD are pathophysiologically related. Bipolar OCD is associated with a higher rate of depressive episodes, higher suicidality and more frequent hospitalizations, suggesting greater morbidity. Long‐term prospective follow‐up studies and studies addressing pathophysiology and genetic basis are needed to understand the complexity of such comorbidity. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5158076 Sun, 31 Jul 2011 23:00:00 +0100 5158076 http://www.medworm.com/index.php?rid=5158075&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02240.x Conclusions:  The study provides important insights into the QOL and perceived burden of caregivers of OCD patients. It highlights the need for improving the quality of care not only for patients but also for primary caregivers. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5158075 Sun, 31 Jul 2011 23:00:00 +0100 5158075 http://www.medworm.com/index.php?rid=5158074&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02239.x There is a need to reduce stigma and increase awareness in order to prevent social exclusion of people with mental illness and to facilitate the use of mental health services in young people. The purpose of this review was to examine the effects of educational interventions to reduce stigmatization and improve awareness of mental health problems among young people. An electronic search using MEDLINE, PsycINFO and Academic Search Complete was carried out for studies that evaluated the effectiveness of educational interventions. Forty eligible studies were identified. There were three types of educational interventions (Educational condition, Video‐based Contact condition and Contact condition). Eighteen of 23 studies reported significant improvements in knowledge, 27 of 34 studies yielded... Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5158074 Sun, 31 Jul 2011 23:00:00 +0100 5158074 http://www.medworm.com/index.php?rid=5158073&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02253.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=5158073 Sun, 31 Jul 2011 23:00:00 +0100 5158073 http://www.medworm.com/index.php?rid=4952509&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02227.x Conclusions:  The findings suggest that the combination of temperaments and/or personality types assessed with the Temperament Evaluation of Memphis, Pisa, Paris and San Diego‐Autoquestionnaire version and the Munich Personality Test may worsen both quality of life and social adaptation and that some temperaments and/or personality types in combination may be subclinical manifestations of mood disorders. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4952509 Wed, 15 Jun 2011 23:00:00 +0100 4952509 http://www.medworm.com/index.php?rid=4952518&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02222.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4952518 Tue, 31 May 2011 23:00:00 +0100 4952518 http://www.medworm.com/index.php?rid=4952517&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02223.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4952517 Tue, 31 May 2011 23:00:00 +0100 4952517 http://www.medworm.com/index.php?rid=4952516&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02221.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4952516 Tue, 31 May 2011 23:00:00 +0100 4952516 http://www.medworm.com/index.php?rid=4952515&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02210.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4952515 Tue, 31 May 2011 23:00:00 +0100 4952515 http://www.medworm.com/index.php?rid=4952514&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02225.x Conclusion:  Increased physical activity by pedometer walking plus individual motivational interviewing may be an effective program for the reduction of bodyweight and BMI in Thai schizophrenic patients who are obese or overweight. Its efficacy may be comparable to other cognitive/behavioral programs. Further studies in larger sample sizes are warranted. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4952514 Tue, 31 May 2011 23:00:00 +0100 4952514 http://www.medworm.com/index.php?rid=4952513&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02219.x Conclusions:  Our findings suggest that the dorsal midbrain is associated with PD pathophysiology. The midbrain volume increase may reflect PD severity. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4952513 Tue, 31 May 2011 23:00:00 +0100 4952513 http://www.medworm.com/index.php?rid=4952512&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02224.x Conclusion:  Yamashita (1977) reported that the majority of offensive subtype patients were doted on by their parents, although current offensive subtype patients are more likely to have had a troubled childhood, show severer forms of SAD, and more frequently exhibit an inflexible personality. This study suggested that the offensive subtype might not be essentially different from the non‐offensive subtype (quantitative rather than qualitative). (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4952512 Tue, 31 May 2011 23:00:00 +0100 4952512 http://www.medworm.com/index.php?rid=4952511&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02226.x Kraepelin's system of mental diseases has contributed substantially to the foundation of modern psychiatric diagnosis in the DSM‐IV and ICD‐10. Considering Kraepelin's influence in the creation of these diagnostic tools, the question arises as to how Kraepelin's contemporaries and successors reacted to his nosology. Historical libraries and archives in Munich, Berlin and Paris were searched for European and American psychiatric literature using the keywords ‘Kraepelin’, ‘dichotomy’ and ‘manic‐depressive disorder’. Literature from 1900 to 1960 was examined and compared to the current literature regarding Kraepelin's impact on modern classification systems. The sixth edition of Kraepelin's ‘Lehrbuch’ (1899) presented the dichotomy in its entirety and led to three differ... Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4952511 Tue, 31 May 2011 23:00:00 +0100 4952511 http://www.medworm.com/index.php?rid=4952510&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02212.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4952510 Tue, 31 May 2011 23:00:00 +0100 4952510 http://www.medworm.com/index.php?rid=4952508&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02228.x Conclusion:  For men in their 20s through their 50s, accessing suicide sites influenced suicidal ideations through depression, and for women in the same age bracket, emotional support influenced suicidal ideations through depression. For men and women over the age of 60, depression strongly influenced suicidal ideations. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4952508 Tue, 31 May 2011 23:00:00 +0100 4952508 http://www.medworm.com/index.php?rid=4828620&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02213.x The purpose of the present study was to provide preliminary data on the usefulness and safety of blonanserin for patients with delirium in the intensive care unit (ICU). The charts of 32 consecutive patients with delirium in the ICU were retrospectively reviewed. These patients were treated with blonanserin. A total of 96.6% had reduction in Memorial Delirium Assessment Scale score. The proportion of patients with side‐effects was 24.1%. Blonanserin may be effective and safe in the treatment of delirium in the ICU. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4828620 Sun, 15 May 2011 23:00:00 +0100 4828620 http://www.medworm.com/index.php?rid=4828619&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02214.x Lithium‐induced polyuria, although common, often goes unrecognized. The purpose of the present study was therefore to investigate the complaints of polyuria, and distress and functional impairment associated with polyuria, in 56 patients with bipolar disorder on long‐term lithium treatment. All participants underwent 24‐h urine collection, and renal function tests. Polyuria (24‐h urine volume > 3 L) was found in 70% of subjects. Unless directly enquired about, polyuria was underreported. Impairment in work and daily routine due to increased urine output/frequency was associated with 24‐h urine volumes. Polyuria is a highly prevalent, distressing and impairing side‐effect of long‐term lithium treatment, requiring due attention. (Source: Psychiatry and Clinical Neurosc... Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4828619 Sun, 15 May 2011 23:00:00 +0100 4828619 http://www.medworm.com/index.php?rid=4828618&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02215.x Conclusions:  Altered sensitivity to negative feedback occurs in mild late‐life unipolar depression and may represent a subtle context‐specific phenomenon. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4828618 Sun, 15 May 2011 23:00:00 +0100 4828618 http://www.medworm.com/index.php?rid=4788829&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02217.x Conclusion:  The results of the study suggest that comorbid alcoholism is a major factor in the death of anorexia nervosa and bulimia nervosa patients. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4788829 Wed, 04 May 2011 23:00:00 +0100 4788829 http://www.medworm.com/index.php?rid=4709024&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02208.x Conclusion:  In the face of a real difference or correlation in population, many depression researchers are less likely to give a valid result than simply tossing a coin. It is important to educate depression researchers in order to enable them to conduct an a priori power analysis. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4709024 Wed, 13 Apr 2011 23:00:00 +0100 4709024 http://www.medworm.com/index.php?rid=4709023&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02209.x In this report, we present two cases with ASD who visited a psychiatric emergency service because of the ‘time slip’ phenomenon, and discuss the clinical significance of this phenomenon. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4709023 Wed, 13 Apr 2011 23:00:00 +0100 4709023 http://www.medworm.com/index.php?rid=4828617&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02216.x Cross‐correlation was examined for the volume of suicide‐related Internet searches and suicide death rate. Analysis of Google data and figures released by the Ministry of Health, Labour, and Welfare indicated that the volume of searches using the search terms jisatsu (suicide) and jisatsu houhou (suicide method) are not correlated with the suicide death rate. In addition, a rising suicide death rate might be related to the increase in suicide‐related search activity (particularly utsu[depression]), but an increase in suicide‐related search activity itself is not directly linked to the rise of suicide death rate. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4828617 Thu, 31 Mar 2011 23:00:00 +0100 4828617 http://www.medworm.com/index.php?rid=4788828&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02218.x Conclusion:  Glucose abnormalities were newly detected in 11.9% of schizophrenia patients treated with second‐generation antipsychotics by the baseline monitoring. To assess the detective power and usefulness of the guidance, longitudinal investigations are necessary. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4788828 Thu, 31 Mar 2011 23:00:00 +0100 4788828 http://www.medworm.com/index.php?rid=4733517&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02207.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4733517 Thu, 31 Mar 2011 23:00:00 +0100 4733517 http://www.medworm.com/index.php?rid=4733516&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02206.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4733516 Thu, 31 Mar 2011 23:00:00 +0100 4733516 http://www.medworm.com/index.php?rid=4733515&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02198.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4733515 Thu, 31 Mar 2011 23:00:00 +0100 4733515 http://www.medworm.com/index.php?rid=4733514&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02195.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4733514 Thu, 31 Mar 2011 23:00:00 +0100 4733514 http://www.medworm.com/index.php?rid=4733513&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02196.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4733513 Thu, 31 Mar 2011 23:00:00 +0100 4733513 http://www.medworm.com/index.php?rid=4733512&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02194.x Aripiprazole, a dopamine D2 receptor partial agonist, has been used to treat schizophrenia and might be effective for alcohol dependence and craving. We treated a 53‐year‐old woman with refractory medication overuse headache, which was successfully treated with aripiprazole. Our experience suggests that aripiprazole may be effective for patients with medication overuse headache. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4733512 Thu, 31 Mar 2011 23:00:00 +0100 4733512 http://www.medworm.com/index.php?rid=4733511&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02205.x Conclusions:  Suicide is likely to occur in a milieu of agitation, mixed anxiety and depression, and psychosis. Longer‐term mood stabilizer treatment may reduce the rate of completed suicide. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4733511 Thu, 31 Mar 2011 23:00:00 +0100 4733511 http://www.medworm.com/index.php?rid=4733510&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02193.x Conclusion:  Although the association was not strong, the result of this study would support the association between DGKH and BD. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4733510 Thu, 31 Mar 2011 23:00:00 +0100 4733510 http://www.medworm.com/index.php?rid=4733509&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02192.x Conclusion:  ED + SIB patients had a more severe ED pathology than ED/no SIB patients, and also felt that they had received low paternal care during childhood. Therefore, paternal care may be linked to severe ED pathology. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4733509 Thu, 31 Mar 2011 23:00:00 +0100 4733509 http://www.medworm.com/index.php?rid=4733508&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02201.x Conclusion:  Although PD and MSA frequently accompany RWA, RBD symptoms often remain non‐violent or silent. Differences in the course of RBD symptoms in patients with PD and MSA may reflect the difference in the degeneration process of the two disorders. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4733508 Thu, 31 Mar 2011 23:00:00 +0100 4733508 http://www.medworm.com/index.php?rid=4733507&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02200.x Conclusions:  These findings suggest that the Chinese version of the Caregiver Reaction Assessment is a reliable and valid instrument for measuring specific aspects of the caregiving experience in the Chinese population. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4733507 Thu, 31 Mar 2011 23:00:00 +0100 4733507 http://www.medworm.com/index.php?rid=4733506&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02191.x Conclusions:  The large increase in the dopamine concentration in the rat mPFC after the combination therapy was unique and may be responsible for the profound antidepressive effect observed in patients with treatment‐resistant depression. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4733506 Thu, 31 Mar 2011 23:00:00 +0100 4733506 http://www.medworm.com/index.php?rid=4733505&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02204.x Conclusions:  These findings suggest that deteriorated risk of SRE in child and adolescent patients receiving antidepressants should not be overestimated while some pretreatment characteristics may be useful to predict the outcome of SRE after antidepressant therapy. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4733505 Thu, 31 Mar 2011 23:00:00 +0100 4733505 http://www.medworm.com/index.php?rid=4733504&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02199.x Conclusions:  Heritable effects likely play an important role in the cause of anxiety disorders, but the extent of their role remains to be established. Important contributions could be made by studies of gene–environment interactions that have sufficient sample sizes to produce reliable results. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4733504 Thu, 31 Mar 2011 23:00:00 +0100 4733504 http://www.medworm.com/index.php?rid=4733503&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02202.x Conclusion:  The results indicate poorer mental health status in the Japanese Group than the Brazilian Group, and suggest the adverse circumstances of the former group both at their homes and schools. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4733503 Thu, 31 Mar 2011 23:00:00 +0100 4733503 http://www.medworm.com/index.php?rid=4733502&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02220.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4733502 Thu, 31 Mar 2011 23:00:00 +0100 4733502 http://www.medworm.com/index.php?rid=4709022&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02211.x We report two cases suffering from visual and auditory hallucinations: Case 1 abruptly stopped taking paroxetine (20 mg/day), and Case 2 discontinued paroxetine after reducing the dose from 20 mg/day to 10 mg/day for 5 months. Both cases experienced visual and auditory hallucinations in addition to dizziness, headache, insomnia, and nausea a couple of days after paroxetine discontinuation. These observations suggest that hallucinations are a part of the discontinuation syndrome that results from paroxetine discontinuation. Physicians should be aware of this symptom. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4709022 Tue, 01 Mar 2011 00:00:00 +0100 4709022 http://www.medworm.com/index.php?rid=4652966&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02203.x Conventional wisdom has not laid out a clear and uniform profile of schizophrenia as a unitary entity. One of the key first steps in elucidating the neurobiology of this entity would be to characterize the essential and common elements in the group of entities called schizophrenia. Kraepelin in his introduction notes ‘the conviction seems to be more and more gaining ground that dementia praecox on the whole represents, a well characterized form of disease, and that we are justified in regarding the majority of the clinical pictures which are brought together here as the expression of a single morbid process, though outwardly they often diverge very far from one another’. But what is that single morbid process? We suggest that just as the uniform defect in all types of cancer is impaire... Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4652966 Tue, 01 Mar 2011 00:00:00 +0100 4652966 http://www.medworm.com/index.php?rid=4605639&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02175.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4605639 Tue, 01 Mar 2011 00:00:00 +0100 4605639 http://www.medworm.com/index.php?rid=4605638&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02188.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4605638 Tue, 01 Mar 2011 00:00:00 +0100 4605638 http://www.medworm.com/index.php?rid=4605637&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02185.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4605637 Tue, 01 Mar 2011 00:00:00 +0100 4605637 http://www.medworm.com/index.php?rid=4605636&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02187.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4605636 Tue, 01 Mar 2011 00:00:00 +0100 4605636 http://www.medworm.com/index.php?rid=4605635&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02184.x The aim of the present 12‐week, open‐label study was to investigate the effect of olanzapine augmentation in outpatients with depression with melancholic features who demonstrated partial response to standard antidepressants but who were reluctant to change antidepressants. The subjects consisted of 22 outpatients meeting the DSM‐IV‐TR criteria for major depression. Olanzapine was initially added at 2.5 mg/day and the dose was adjusted according to the clinical condition. Data were analyzed using an intention‐to‐treat methodology. A paired t‐test was used to compare total Montgomery Asberg Depression Rating Scale (MADRS) scores before treatment, at baseline (prior to olanzapine), and 4, 8, and 12 weeks after starting olanzapine. Of 22 enrolled patients, 20 completed the t... Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4605635 Tue, 01 Mar 2011 00:00:00 +0100 4605635 http://www.medworm.com/index.php?rid=4605634&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02189.x Conclusions:  Paroxetine single acute administration diminished brain activity induced by motivation in healthy subjects. This may partially explain the increased lack of motivation seen in patients with relatively mild symptoms after taking a dose of paroxetine for the first time. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4605634 Tue, 01 Mar 2011 00:00:00 +0100 4605634 http://www.medworm.com/index.php?rid=4605633&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02179.x Conclusion:  Our results indicate that abnormal activation in prefrontal areas engaged during working memory may be critical to domains of psychopathology, in particular disorganized thought‐processing in patients with SLPE. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4605633 Tue, 01 Mar 2011 00:00:00 +0100 4605633 http://www.medworm.com/index.php?rid=4605632&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02183.x Conclusion:  The antidepressant effects of LFRS in treatment‐resistant depression may be associated with decreases in rCBF in the orbitofrontal cortex and the subgenual cingulate cortex via the right prefrontal cortex. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4605632 Tue, 01 Mar 2011 00:00:00 +0100 4605632 http://www.medworm.com/index.php?rid=4605631&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02180.x Conclusions:  Despite a general interest, general psychiatrists in Japan tend to possess insufficient knowledge of this subspecialty and lack experience in and opportunities to work in this subspecialty. The reluctance of psychiatrists to work in forensic mental health might be partly responsible for this situation. These results suggest that the enrichment of education systems for forensic psychiatry is necessary for the development of forensic psychiatry in Japan. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4605631 Tue, 01 Mar 2011 00:00:00 +0100 4605631 http://www.medworm.com/index.php?rid=4605630&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02181.x Conclusions:  It is possible that the increase in 5‐HT in response to glycine and d‐serine was mediated by N‐methyl‐D‐aspartate receptors. The transient increase in 5‐HT in the PFC might be associated with the alleviation of negative symptoms in patients with schizophrenia and the amelioration of sleep quality in patients with insomnia. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4605630 Tue, 01 Mar 2011 00:00:00 +0100 4605630 http://www.medworm.com/index.php?rid=4605629&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02178.x Mitochondria provide most of the energy production in cells. They are involved in the regulation of free radicals, calcium buffering, and redox signaling and take part in the intrinsic pathway of apoptosis. Mutations or polymorphisms of mitochondrial DNA, mitochondria‐mediated oxidative stress, decrease of adenosine triphosphate production, changes of intracellular calcium and oxidative stress are concerned in various diseases. There is increasing evidence that impaired functions of mitochondria are associated with mood disorders. It is suggested that disturbed energetic metabolism and/or reactive oxygen species production take part in the pathophysiology of mood disorders and could participate in the therapeutic effects or side‐effects of antidepressants and mood stabilizers. (Source:... Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4605629 Tue, 01 Mar 2011 00:00:00 +0100 4605629 http://www.medworm.com/index.php?rid=4605628&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02182.x Cognitive therapy/cognitive behavior therapy was introduced into the field of psychiatry in the late 1980s in Japan, and the Japanese Association for Cognitive Therapy (JACT), founded in 2004, now has more than 1500 members. Along with such progress, awareness of the effectiveness of cognitive therapy/cognitive behavioral therapy has spread, not only among professionals and academics but also to the public. The Study Group of the Procedures and Effectiveness of Psychotherapy, funded by the Ministry of Health, Labor and Welfare, has conducted a series of studies on the effectiveness of cognitive therapy/cognitive behavior therapy since 2006 and shown that it is feasible for Japanese patients. As a result, in April 2010 cognitive therapy/cognitive behavior therapy for mood disorders was adde... Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4605628 Tue, 01 Mar 2011 00:00:00 +0100 4605628 http://www.medworm.com/index.php?rid=4605627&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02197.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4605627 Tue, 01 Mar 2011 00:00:00 +0100 4605627 http://www.medworm.com/index.php?rid=4507074&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2011.02190.x Twin, family, and adoption studies have consistently shown that genetic factors play an important role in the pathogenesis of alcohol dependence. Numerous studies have aimed to identify genes that contribute to susceptibility to alcohol dependence. Whole‐genome linkage studies have identified several chromosomal regions that are linked with alcohol dependence. Association studies have also identified genes associated with alcohol dependence. Alcohol‐metabolizing enzymes, such as alcohol dehydrogenase‐1B and aldehyde dehydrogenase‐2, are the most well‐established genes that have polymorphisms associated with the risk for alcohol dependence. Polymorphisms in gamma‐aminobutyric acid receptor genes are also reported to be associated with alcohol dependence. The polymorphism of opio... Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4507074 Tue, 01 Feb 2011 00:00:00 +0100 4507074 http://www.medworm.com/index.php?rid=4399280&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02173.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4399280 Wed, 26 Jan 2011 18:13:20 +0100 4399280 http://www.medworm.com/index.php?rid=4399279&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02167.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4399279 Wed, 26 Jan 2011 18:13:19 +0100 4399279 http://www.medworm.com/index.php?rid=4399278&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02158.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4399278 Wed, 26 Jan 2011 18:13:19 +0100 4399278 http://www.medworm.com/index.php?rid=4399277&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02172.x Our aim was to assess the internal consistency and structural/construct validity of the Center for Epidemiological Studies Depression Scale among middle‐aged employees in Japan. We conducted a cross‐sectional study of 7284 workers, aged 49.0 ± 6.3 (mean ± SD) years old. Structural/construct validity was assessed by confirmatory factor analysis. The 4‐factor structure reported in the general population was replicated, and a second‐order model with an overarching depression factor fitted well. These findings indicate that the Center for Epidemiological Studies Depression Scale is a valid and reliable measure of depressive symptoms for middle‐aged workers in Japan. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4399277 Wed, 26 Jan 2011 18:13:18 +0100 4399277 http://www.medworm.com/index.php?rid=4399276&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02169.x Metachromatic leukodystrophy (MLD) is an autosomal recessive lysosomal storage disease caused by a deficiency of arylsulfatase A. MLD is a heterogeneous disease with variable age at onset and variable clinical features. We evaluated a 33‐year‐old female patient who developed manifestations of disinhibitory behavior. She was diagnosed with MLD by genetic analysis, which revealed compound heterozygous ARSA missense mutations (p.G99D and p.T409I). The same combination of mutations was previously reported in a Japanese patient with similar symptoms. We performed additional, detailed neuropsychological tests with functional imaging on the current patient that demonstrated frontal lobe dysfunction. These results indicate that the mutations have important implications for genotype–phenotype... Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4399276 Wed, 26 Jan 2011 18:13:17 +0100 4399276 http://www.medworm.com/index.php?rid=4399275&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02165.x Delirium is a complex multifactorial neuropsychiatric syndrome with a broad range of cognitive and neurobehavioral symptoms. It is associated with major adverse events and poor outcome. Little is known about delirium in the primary care setting. A retrospective chart review was carried out for the identification of ICD‐10 delirium cases presented in the regional medical office of a rural area in central Greece. Nine cases of delirium, mostly the hyperactive subtype, had been recorded. The patients tended to be elderly and suffering from dementia; infections were the underlying cause in most cases. All but one patient had been successfully treated in the primary care setting. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4399275 Wed, 26 Jan 2011 18:13:15 +0100 4399275 http://www.medworm.com/index.php?rid=4399274&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02174.x Conclusion:  The use of ‘togo‐shitcho‐sho’ in official documents has become established. On the other hand, terms such as ‘nervous breakdown’ and ‘depressive state’ are still commonly used in private documents after the adoption of the new Japanese translation of schizophrenia. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4399274 Wed, 26 Jan 2011 18:13:14 +0100 4399274 http://www.medworm.com/index.php?rid=4399273&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02171.x Conclusions:  The prevalence of depressive symptoms differed when assessed with CES‐D and HADS‐D. The reasons behind this difference include the fact that HADS‐D frequently detected depressive symptoms in patients with mild COPD as well as a tendency for HADS‐D to be strongly influenced by education levels. In contrast, the severity of COPD was reflected in CES‐D. It is possible that prevalence of depressive symptoms differs in accordance with the applied screening tool. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4399273 Wed, 26 Jan 2011 18:13:13 +0100 4399273 http://www.medworm.com/index.php?rid=4399272&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02170.x Conclusion:  Our results suggest that hippocampal neurogenesis might be involved in the antidepressant effects of chronic rTMS. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4399272 Wed, 26 Jan 2011 18:13:12 +0100 4399272 http://www.medworm.com/index.php?rid=4399271&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02166.x Conclusion:  Cognitive subdomains might be considered important for including in patient‐administered questionnaires used to measure symptoms of MDD when developing a new scale. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4399271 Wed, 26 Jan 2011 18:13:12 +0100 4399271 http://www.medworm.com/index.php?rid=4399270&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02163.x Conclusion:  The Japanese‐version Cognitive Therapy Awareness Scale was successfully validated. It has been demonstrated that the scale specifically assess knowledge in cognitive behavioral therapy. This scale would serve as a rough guide to assess competencies among beginner cognitive behavior therapists. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4399270 Wed, 26 Jan 2011 18:13:11 +0100 4399270 http://www.medworm.com/index.php?rid=4399269&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02159.x Conclusions:  This study showed that atomoxetine was well tolerated in these patients and suggested that atomoxetine at a maximum dose of 120 mg/day would be safe in Japanese ADHD patients. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4399269 Wed, 26 Jan 2011 18:13:10 +0100 4399269 http://www.medworm.com/index.php?rid=4399268&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02160.x Conclusion:  Our paper highlights the importance of evaluating MetS even in young patients with bipolar disorder, especially males. The strong association with lack of physical exercise suggests that the implementation of healthy behaviors might be relevant in order to prevent MetS and future adverse cardiovascular outcomes. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4399268 Wed, 26 Jan 2011 18:13:10 +0100 4399268 http://www.medworm.com/index.php?rid=4399267&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02168.x Central nervous system disorders are the third greatest health problem in developed countries, and schizophrenia represents some of the most disabling ailments in young individuals. There is an abuse and/or misuse of antipsychotics, and recent advances in pharmacogenomics pose new challenges for the clinical management of this complex disorder. Schizophrenia is a multi‐factorial/polygenic complex disorder in which hundreds of different genes are potentially involved, leading to the phenotypic expression of the disease in conjunction with epigenetic and environmental phenomena. Consequently, structural and functional genomic changes induce proteomic and metabolomic defects associated with the disease phenotype.Disease‐related genomic profiles and genetic variants in genes involved in dr... Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4399267 Wed, 26 Jan 2011 18:13:08 +0100 4399267 http://www.medworm.com/index.php?rid=4399266&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02186.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4399266 Wed, 26 Jan 2011 18:13:08 +0100 4399266 http://www.medworm.com/index.php?rid=4349374&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02176.x Conclusions:  This study does not clearly support the hypothesis that hypoxic/ischemic processes are behind the pathological deficits in the frontal‐subcortical circuitry associated with depression and therefore does not provide evidence to support the ‘vascular depression’ hypothesis. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4349374 Fri, 14 Jan 2011 00:00:00 +0100 4349374 http://www.medworm.com/index.php?rid=4349373&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02177.x Conclusion:  Anger attacks are common among depressive and anxiety disorder cases and have a negative impact on quality of life. Status of anger attacks as either linked to anxiety and/or depression, or as an independent syndrome needs further study. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4349373 Wed, 01 Dec 2010 00:00:00 +0100 4349373 http://www.medworm.com/index.php?rid=4281095&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02164.x Cortical and central white matter (WM) volumes were measured to assess short‐ and long‐range connectivity in autism, respectively. Subjects included 23 boys with autism and 23 matched controls, all without intellectual disability. Magnetic resonance imaging data obtained at 1.5 T were analyzed using BRAINS2 software (University of Iowa, Iowa City, IA, USA). Central WM volume was quantified by subtracting cortical from supratentorial WM volumes. Reduced central WM volume was observed in the autism group. IQ was higher in controls with no observed correlations between WM volumes and IQ. This preliminary evidence of reduced central WM volume in autism suggests abnormal long‐range connectivity. (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4281095 Wed, 01 Dec 2010 00:00:00 +0100 4281095 http://www.medworm.com/index.php?rid=4224860&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02156.x This study examined prolactin levels, sexual function and clinical improvement after switching to aripiprazole from risperidone. Nine schizophrenic male Chinese patients who reported risperidone‐induced sexual dysfunction were studied. Clinical Global Impression Scale Scores for Severity (CGI‐S), Clinical Global Impression Scale Scores for Improvement (CGI‐I), Arizona Sexual Experience Scale results and serum prolactin concentrations were determined over 16 weeks. After treatment with aripiprazole, all patients showed reduced serum prolactin (26.54 ± 17.03 ng/mL to 3.71 ± 1.87 ng/mL, P = 0.008) and five reported improved sexual function. Mean baseline CGI‐S (5.11 ± 0.93) decreased to 3.78 ± 1.39 (P = 0.010) by week 16. Compared to baseline (4.0), the... Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4224860 Wed, 01 Dec 2010 00:00:00 +0100 4224860 http://www.medworm.com/index.php?rid=4200408&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02162.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4200408 Thu, 25 Nov 2010 18:04:44 +0100 4200408 http://www.medworm.com/index.php?rid=4200407&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02138.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4200407 Thu, 25 Nov 2010 18:04:43 +0100 4200407 http://www.medworm.com/index.php?rid=4200406&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02141.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4200406 Thu, 25 Nov 2010 18:04:43 +0100 4200406 http://www.medworm.com/index.php?rid=4200405&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02144.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4200405 Thu, 25 Nov 2010 18:04:42 +0100 4200405 http://www.medworm.com/index.php?rid=4200404&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02146.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4200404 Thu, 25 Nov 2010 18:04:42 +0100 4200404 http://www.medworm.com/index.php?rid=4200403&cid=s_27177_168_f&fid=27177&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1440-1819.2010.02153.x (Source: Psychiatry and Clinical Neurosciences) Psychiatry and Clinical Neurosciences journals http://www.medworm.com/rss/comments.php?id=4200403 Thu, 25 Nov 2010 18:04:41 +0100 4200403