MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'The American Journal of Drug and Alcohol Abuse' source. Tue, 07 Feb 2012 12:26:47 +0100 http://www.medworm.com/index.php?rid=5624483&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22263960%26dopt%3DAbstract Conclusion: All opiate addicts under substitution therapy present with neurological abnormalities. The high prevalence of neurological abnormalities in opiate addicts implies regular referral of these patients to the neurologist to improve their outcome. PMID: 22263960 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5624483 Fri, 20 Jan 2012 05:00:00 +0100 5624483 http://www.medworm.com/index.php?rid=5624485&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22257306%26dopt%3DAbstract Conclusions and Significance: Methamphetamine-dependent individuals exhibit cognitive performance deficits that are more pronounced during exposure to methamphetamine-related cues. Interventions that reduce cue reactivity may have utility in the treatment of methamphetamine dependence. PMID: 22257306 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5624485 Thu, 19 Jan 2012 05:00:00 +0100 5624485 http://www.medworm.com/index.php?rid=5624484&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22257321%26dopt%3DAbstract Conclusion: EPHX1 gene polymorphisms and haplotypes are associated with an increased risk for alcoholism in the Kota population. This is the first report from India that will serve as a template for future investigations of the prevalence of EPHX1 alleles in association with various clinical entities. PMID: 22257321 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5624484 Thu, 19 Jan 2012 05:00:00 +0100 5624484 http://www.medworm.com/index.php?rid=5603984&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22242558%26dopt%3DAbstract Conclusions: These data suggest that marijuana-dependent young adults with comorbid ASPD do not necessarily have poorer retention or substance use outcomes compared with marijuana-dependent young adults who do not have ASPD when treated in a well-defined behavioral therapy protocol. Scientific significance: Previous research has shown increased risks for clients with comorbid ASPD and marijuana dependence; however, our findings suggest that specialized programs for clients with ASPD may not be necessary if they are provided with empirically supported, structured treatments. PMID: 22242558 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5603984 Fri, 13 Jan 2012 05:00:00 +0100 5603984 http://www.medworm.com/index.php?rid=5603983&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22242567%26dopt%3DAbstract Conclusion: A higher number of motives, as well as specific motives reported for sedative use, were found to be significantly associated with past 12-month SSAU. Scientific significance: Findings underscore the need for considering motives in tailoring preventive interventions for reducing SSAU. It may be equally important to direct efforts toward decreasing the number of motives, as well as addressing the specific motives reported for sedative use. PMID: 22242567 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5603983 Fri, 13 Jan 2012 05:00:00 +0100 5603983 http://www.medworm.com/index.php?rid=5603982&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22242619%26dopt%3DAbstract Conclusions and Scientific Significance: While not providing resounding support for mentoring, this study suggests that examining the mentor/mentee relationship may be a fruitful line of future research given that significant variability among the mentor/mentee pairs was noted for some outcomes of interest. PMID: 22242619 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5603982 Fri, 13 Jan 2012 05:00:00 +0100 5603982 http://www.medworm.com/index.php?rid=5603981&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22242643%26dopt%3DAbstract Conclusions: Participants had a clear preference for a particular medication. Offering a choice of medications to OT individuals might enhance their likelihood of entering treatment. Treatment programs should offer a choice of medications when possible to new patients, and future comparative effectiveness research should incorporate patient preferences into clinical trials. Scientific Significance: These data contribute to our understanding of why people seek or do not seek effective pharmacotherapy for opioid addiction. PMID: 22242643 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5603981 Fri, 13 Jan 2012 05:00:00 +0100 5603981 http://www.medworm.com/index.php?rid=5603980&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22242680%26dopt%3DAbstract Conclusions and Scientific Significance: These results suggest that providers of workforce development services for drug users in treatment or exiting treatment should attend to these specific barriers to employment, which may also be more pronounced among older clients. PMID: 22242680 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5603980 Fri, 13 Jan 2012 05:00:00 +0100 5603980 http://www.medworm.com/index.php?rid=5603979&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22242700%26dopt%3DAbstract Conclusions: Hepatitis C treatment can be successfully integrated into a methadone maintenance clinic, and mDOT can be implemented with a methadone clinic's existing nursing and medical staff. Patients struggling with concurrent substance use and mental illness comorbidity may be successfully addressed in such settings and facilitate access to and completion of treatment through the utilization of on-site clinical services for HCV treatment and adherence support with mDOT. The exact importance of site of services and adherence support remains a significant area for future investigation. PMID: 22242700 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5603979 Fri, 13 Jan 2012 05:00:00 +0100 5603979 http://www.medworm.com/index.php?rid=5603978&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22242740%26dopt%3DAbstract Conclusions: Considering the limited HCV knowledge and low level of HCV treatment received, effective HCV education and intervention strategies should be developed to target patients in China's MMT clinics. Moreover, alcohol screening should also be part of the routine assessments within MMT programs. Scientific Significance: This study reveals the importance of HCV testing and education among drug users in MMT clinics. PMID: 22242740 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5603978 Fri, 13 Jan 2012 05:00:00 +0100 5603978 http://www.medworm.com/index.php?rid=5603977&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22242792%26dopt%3DAbstract Conclusions: Cannabis, amphetamine, and opiate use are associated with an increased risk of becoming a forensic psychiatric patient, but no substantial differences were observed among patients with psychosis diagnosis in the relative risk increase for cannabis versus amphetamine versus opiate use, indicating that none of these drugs are uniquely associated with violent offending among mentally ill. PMID: 22242792 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5603977 Fri, 13 Jan 2012 05:00:00 +0100 5603977 http://www.medworm.com/index.php?rid=5603976&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22243417%26dopt%3DAbstract Conclusions: Depressive symptoms in fathers entering SA treatment have implications for both the severity of drug abuse and negative parenting behaviors. PMID: 22243417 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5603976 Fri, 13 Jan 2012 05:00:00 +0100 5603976 http://www.medworm.com/index.php?rid=5603975&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22243427%26dopt%3DAbstract Conclusions and Scientific Significance: It is expected that the suggested adaptations for IPT will enable IPT treatment to be more effective. Scientific evaluation of IPT for substance abuse is encouraged with the adoption of these proposed adaptations. PMID: 22243427 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5603975 Fri, 13 Jan 2012 05:00:00 +0100 5603975 http://www.medworm.com/index.php?rid=5603974&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22243486%26dopt%3DAbstract Conclusions: Nontreatment seekers are at higher HIV risk than those entering MTPs and should be a focus of sex-risk reduction interventions, even if they are not interested in treatment at that time. PMID: 22243486 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5603974 Fri, 13 Jan 2012 05:00:00 +0100 5603974 http://www.medworm.com/index.php?rid=5603985&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22233189%26dopt%3DAbstract Conclusions and Scientific Significance: Preliminary results elucidate neurobiological mechanisms of OD and support the utility of controlled studies on a novel VLNTX + low-dose clonidine combination for the management of opioid withdrawal. Portions of this article were presented at the American Society of Addiction Medicine, 42nd Annual Medical Scientific Conference, April 14-17, 2011, in Washington, DC. PMID: 22233189 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5603985 Tue, 10 Jan 2012 05:00:00 +0100 5603985 http://www.medworm.com/index.php?rid=5578846&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22220502%26dopt%3DAbstract Conclusions: In this small study, adolescent oxycodone abusers use high quantities of oxycodone at a time, alter routes of administration for not only extended-release but also immediate-release products, and commonly abuse single-entity oxycodone products. Abuse-deterrent formulations may be one strategy for addressing such behaviors. PMID: 22220502 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5578846 Thu, 05 Jan 2012 05:00:00 +0100 5578846 http://www.medworm.com/index.php?rid=5578845&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22220556%26dopt%3DAbstract Conclusions and scientific significance: These findings highlight the potential utility of performance-based measures for delineating the psychological mechanisms associated with variation in response to treatment for drug dependence. PMID: 22220556 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5578845 Thu, 05 Jan 2012 05:00:00 +0100 5578845 http://www.medworm.com/index.php?rid=5578844&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22220585%26dopt%3DAbstract Conclusion: According to the route of drug administration, drug dependents differed in terms of personality disorders and dimensions. Scientific Significance: These results may have implications for the implementation of treatment programs. New research in this area may contribute to the understanding and prevention of intravenous drug use. PMID: 22220585 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5578844 Thu, 05 Jan 2012 05:00:00 +0100 5578844 http://www.medworm.com/index.php?rid=5578843&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22220630%26dopt%3DAbstract Conclusions and Scientific Significance: Individual differences in reinforcement sensitivity may influence the acquisition of positive and negative outcome expectancies, thereby potentially influencing the likelihood of alcohol use in early adolescence. Thus, reinforcement sensitivity theory is a promising theory to account for the link between neural models of addiction and early acquisition of alcohol use in humans. PMID: 22220630 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5578843 Thu, 05 Jan 2012 05:00:00 +0100 5578843 http://www.medworm.com/index.php?rid=5578842&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22221171%26dopt%3DAbstract Conclusions and Scientific Significance: The results of this study suggest that mirtazapine is superior to placebo in improving sleep in patients with comorbid depression and cocaine dependence, but is not more effective than placebo in reducing cocaine use. PMID: 22221171 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5578842 Thu, 05 Jan 2012 05:00:00 +0100 5578842 http://www.medworm.com/index.php?rid=5578841&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22221190%26dopt%3DAbstract Conclusions: Challenges and strategies surrounding diagnosis and treatment are described, which may be useful as "bath salt" use becomes more widespread. Scientific Significance: As an emerging trend, bath salt intoxication delirium appears to cause intense psychosis that can be managed with antipsychotic medications. Clinicians should be aware of this phenomenon until more precise detection methods are available. PMID: 22221190 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5578841 Thu, 05 Jan 2012 05:00:00 +0100 5578841 http://www.medworm.com/index.php?rid=5578840&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22221229%26dopt%3DAbstract Conclusion: Although the use of illicit drugs is widespread, there are little experimental or clinical data regarding the effects of these agents on common prescription therapies. Scientific Significance: Potential drug interactions between illicit drugs and prescription drugs are described and evaluated on the Drug Interaction Probability Scale by Horn and Hansten. PMID: 22221229 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5578840 Thu, 05 Jan 2012 05:00:00 +0100 5578840 http://www.medworm.com/index.php?rid=5578839&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22221277%26dopt%3DAbstract Conclusion: The results suggest that the use of a comprehensive behavioral intervention paired with naltrexone leads to significant reductions in drug use and legal problems in opioid-injecting males in the Republic of Georgia. Scientific Significance: A comprehensive intervention that paired behavioral treatment with naltrexone provides a promising approach to protect drug users against relapse and legal risks. PMID: 22221277 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5578839 Thu, 05 Jan 2012 05:00:00 +0100 5578839 http://www.medworm.com/index.php?rid=5561593&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22211461%26dopt%3DAbstract Conclusions and Scientific Significance: A cross-discipline consideration of how addicts manage their funds has the potential to inform and improve substance abuse treatment. PMID: 22211461 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5561593 Tue, 03 Jan 2012 05:00:00 +0100 5561593 http://www.medworm.com/index.php?rid=5561592&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22211484%26dopt%3DAbstract Conclusions and Scientific Significance: The consideration of the systematic biases in human decision making that have been revealed in behavioral economics research has the potential to enhance efforts to devise effective strategies for improving money management skills among those with SUDs. PMID: 22211484 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5561592 Tue, 03 Jan 2012 05:00:00 +0100 5561592 http://www.medworm.com/index.php?rid=5561591&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22211535%26dopt%3DAbstract Conclusions: Future research on the relationships between delay discounting, substance abuse, and financial mismanagement can provide important insights for developing improved prevention and treatment strategies. PMID: 22211535 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5561591 Tue, 03 Jan 2012 05:00:00 +0100 5561591 http://www.medworm.com/index.php?rid=5561590&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22211586%26dopt%3DAbstract Conclusions: The findings demonstrate that, in this sample, nonmedical prescription opioid use is dissimilar among rural and urban drug users. Additional research is needed to better understand the individual, social, and structural level factors contributing to the burden of nonmedical opioid use, particularly in rural populations, with the aim of developing tailored substance abuse treatment and prevention. PMID: 22211586 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5561590 Tue, 03 Jan 2012 05:00:00 +0100 5561590 http://www.medworm.com/index.php?rid=5536682&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22185328%26dopt%3DAbstract Conclusions and Significance: Overall, our findings suggest that participants use their research payments in a responsible and safe manner. Limitations and recommendations for future research are discussed. PMID: 22185328 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5536682 Wed, 21 Dec 2011 05:00:00 +0100 5536682 http://www.medworm.com/index.php?rid=5536681&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22185368%26dopt%3DAbstract Conclusion: When controlling for the presence of an affective disorder, SD patients exhibited elevated frustration intolerance, suggesting that this may be a particularly difficult type of distress for this group. Scientific significance: DI is linked to important clinical outcomes and can be modified with treatment. Identification of intolerance of specific domains of distress associated with select disorders may help to better target such interventions. PMID: 22185368 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5536681 Wed, 21 Dec 2011 05:00:00 +0100 5536681 http://www.medworm.com/index.php?rid=5536686&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22175698%26dopt%3DAbstract Conclusions and scientific significance: Using flexible buprenorphine dosing schedule with the option of titrating the dose up to 32 mg daily may offer better treatment outcome for patients who would not respond to the lower dose range. PMID: 22175698 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5536686 Mon, 19 Dec 2011 05:00:00 +0100 5536686 http://www.medworm.com/index.php?rid=5536685&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22175771%26dopt%3DAbstract Conclusions: The HCV infection was popular among opiate drug users in Beijing. The findings indicated the need for educating the users taking into account their low literacy levels and the necessity for job training and decreasing the injection drug use and the frequency of drug use administrated as the prevention and intervention methods for controlling the HIV/HCV infection in this population. PMID: 22175771 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5536685 Mon, 19 Dec 2011 05:00:00 +0100 5536685 http://www.medworm.com/index.php?rid=5536684&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22175806%26dopt%3DAbstract Conclusions and Scientific Significance: Using an anthropological approach toward understanding the issues surrounding money management for individuals struggling with addiction and mental illness has the potential to strengthen the design and implementation of money-management-based interventions in a manner that is acceptable and meaningful for this target population. PMID: 22175806 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5536684 Mon, 19 Dec 2011 05:00:00 +0100 5536684 http://www.medworm.com/index.php?rid=5536683&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22175869%26dopt%3DAbstract Conclusion: Scales have relatively good psychometric properties and replication is needed. Scientific Significance: GHB-specific measures may greatly assist in furthering our understanding of protective and risk factors for use, and withdrawal phenomena. PMID: 22175869 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5536683 Mon, 19 Dec 2011 05:00:00 +0100 5536683 http://www.medworm.com/index.php?rid=5536687&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22149758%26dopt%3DAbstract Conclusions: Contingency management (CM) increases choice for drug abstinence via the availability of immediate, financial-based gains, contingent on objective evidence of abstinence. PMID: 22149758 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5536687 Tue, 13 Dec 2011 05:00:00 +0100 5536687 http://www.medworm.com/index.php?rid=5457034&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22115359%26dopt%3DAbstract Authors: PMID: 22115359 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5457034 Fri, 25 Nov 2011 05:00:00 +0100 5457034 http://www.medworm.com/index.php?rid=5247735&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21936751%26dopt%3DAbstract Conclusion: These findings suggest that variations in the amount of compensation for completing assessments can differentially affect outcome measurements, depending on treatment group assignment. Scientific Significance: Adequate financial compensation may minimize bias when treatment condition is associated with differential dropout and may be a cost-effective way to reduce attrition. Moreover, active users may be more likely than non-active users to drop out if compensation is inadequate, especially in control groups or in groups who are not receiving active treatment. PMID: 21936751 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5247735 Thu, 22 Sep 2011 04:00:00 +0100 5247735 http://www.medworm.com/index.php?rid=5157666&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21854267%26dopt%3DAbstract Authors: Nunes EV PMID: 21854267 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5157666 Fri, 26 Aug 2011 04:57:57 +0100 5157666 http://www.medworm.com/index.php?rid=5157665&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21854268%26dopt%3DAbstract Authors: PMID: 21854268 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5157665 Fri, 26 Aug 2011 04:57:53 +0100 5157665 http://www.medworm.com/index.php?rid=5157664&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21854269%26dopt%3DAbstract Conclusions: Areas of focus for the CTN's future include defining common outcome measures to be used in treatment outcome studies for illicit drugs; incorporating performance indicators and measures of clinical significance; conducting comparative outcome studies; contributing to the understanding of effective treatments of comorbidity; reaching underserved populations; building implementation science; understanding long-term outcomes of current treatments and sustaining treatment effects; and conducting future trials more efficiently. PMID: 21854269 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5157664 Fri, 26 Aug 2011 04:57:49 +0100 5157664 http://www.medworm.com/index.php?rid=5157663&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21854270%26dopt%3DAbstract Conclusion/Significance: While the feasibility of engaging frontline providers in this research is highlighted, the limitations of small to medium effect sizes and weak adoption and sustainability in everyday practice are also discussed. PMID: 21854270 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5157663 Fri, 26 Aug 2011 04:57:45 +0100 5157663 http://www.medworm.com/index.php?rid=5157662&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21854271%26dopt%3DAbstract Conclusion: Clinicians and researchers should consider individual relationship context and behavior and avoid assuming that recent monogamy or being in a committed relationship denotes low risk. Scientific Significance: This study provides evidence that, in male drug users, monogamy does not necessarily reflect low sexual risk. Rather, "monogamous" men actually encompass various combinations of partner types and levels of risk behavior that are unstable, even over brief time periods. Clinicians and researchers must take these variations into account. PMID: 21854271 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5157662 Fri, 26 Aug 2011 04:57:41 +0100 5157662 http://www.medworm.com/index.php?rid=5157661&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21854272%26dopt%3DAbstract Conclusions: These published studies have expanded the evidence base regarding interventions for vulnerable groups of women with SUDs as well as gender-specific interventions to reduce HIV risk behaviors in substance-using men and women. The results also underscore the complexity of accounting for gender in the design of clinical trials and analysis of results. Scientific Significance: To fully understand the relevance of gender-specific moderators and mediators of outcome, it is essential that future translational studies adopt more sophisticated approaches to understanding and measuring gender-relevant factors and plan sample sizes that are adequate to support more nuanced analytic methods. PMID: 21854272 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5157661 Fri, 26 Aug 2011 04:57:36 +0100 5157661 http://www.medworm.com/index.php?rid=5157660&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21854273%26dopt%3DAbstract Conclusions: Important gender differences in the clinical profiles of opioid-dependent individuals were observed with regard to substance use severity, craving, medical conditions, and impairment in associated areas of functioning. The findings enhance understanding of the characteristics of treatment-seeking men and women with opioid dependence, and may be useful in improving identification, prevention, and treatment efforts for this challenging and growing population. PMID: 21854273 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5157660 Fri, 26 Aug 2011 04:57:33 +0100 5157660 http://www.medworm.com/index.php?rid=5157659&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21854274%26dopt%3DAbstract Conclusions: Seven recommendations are included for conducting more effective research on REMs. PMID: 21854274 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5157659 Fri, 26 Aug 2011 04:57:29 +0100 5157659 http://www.medworm.com/index.php?rid=5157658&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21854275%26dopt%3DAbstract Conclusion: True, collaborative research partnerships require a great deal of time and effort in order to develop mutual trust, understanding, knowledge, and collaboration that will guide research that is rigorous as well as ethical, effective, and culturally appropriate. Scientific Significance: As AIAN communities become increasingly sophisticated partners in, and consumers of, research, CBPR and TPR are emerging as effective, ethical, culturally appropriate, and acceptable approaches. This can serve to improve the science we engage in with AIAN communities, add to the scarce literature regarding AIAN communities, and better serve AIAN communities in addressing health disparities and improving health. PMID: 21854275 [PubMed - in process] (Source: The American Journal of Drug and Alco... The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5157658 Fri, 26 Aug 2011 04:57:24 +0100 5157658 http://www.medworm.com/index.php?rid=5157657&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21854276%26dopt%3DAbstract Conclusion: We concluded that the best current choice for a primary endpoint is percent days abstinent, as measured by the Time Line Follow Back interview conducted three times a week with recall aided by a take-home Substance Use Diary. To improve the accuracy of the self-reported drug use, the results of qualitative urine drug screens will be used in conjunction with the Time Line Follow Back results. Scientific Significance: There is a need for a standardized endpoint in this field to allow for comparison across treatment studies, and we suggest that the recommended candidate endpoint be considered. However, the study design and goals ultimately must guide the final decision. PMID: 21854276 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5157657 Fri, 26 Aug 2011 04:57:20 +0100 5157657 http://www.medworm.com/index.php?rid=5157656&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21854277%26dopt%3DAbstract Conclusions: Further investigation is needed to determine if simple, naïve procedures such as the ELCON algorithms are optimal for comparing clinical study treatment arms. But researchers who currently require an automated algorithm in scenarios similar to those simulated for combining TLFB and UDS to test group differences in stimulant use should consider one of the ELCON algorithms. Scientific Significance: This analysis continues a line of inquiry which could determine how best to measure outpatient stimulant use in clinical trials (NIDA. NIDA Monograph-57: Self-Report Methods of Estimating Drug Abuse: Meeting Current Challenges to Validity. NTIS PB 88248083. Bethesda, MD: National Institutes of Health, 1985; NIDA. NIDA Research Monograph 73: Urine Testing for Drugs of Abuse. NTIS PB 8... The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5157656 Fri, 26 Aug 2011 04:57:16 +0100 5157656 http://www.medworm.com/index.php?rid=5157655&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21854278%26dopt%3DAbstract Conclusion: Despite strong associations between candidate measures, we found some important differences in results. Scientific Significance: In this study, we demonstrated the potential utility and impact of combining UDS and self-report data for drug use assessment. Our results suggest possible differences in intervention efficacy by gender and ethnicity, but highlight the need to cautiously interpret observed interactions. PMID: 21854278 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5157655 Fri, 26 Aug 2011 04:57:12 +0100 5157655 http://www.medworm.com/index.php?rid=5157654&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21854279%26dopt%3DAbstract Conclusions and Scientific Significance: This article illustrates the consequences of applying models with different distribution assumptions on the data. If a model used does not closely fit the shape of the data distribution, the estimate of the effect of the intervention may be biased, either over- or underestimating the intervention effect. PMID: 21854279 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5157654 Fri, 26 Aug 2011 04:57:08 +0100 5157654 http://www.medworm.com/index.php?rid=5157653&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21854280%26dopt%3DAbstract Conclusion: Age and study participation are significantly predictive of cocaine-use behavior. Scientific Significance: The two-stage decision process as modeled by a hurdle binomial model (appropriate for bounded count data with excess zeroes) provides interesting insights into the study of covariate effects on count responses of substance use, when all enrolled subjects are believed to be "at-risk" of use. PMID: 21854280 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5157653 Fri, 26 Aug 2011 04:57:04 +0100 5157653 http://www.medworm.com/index.php?rid=5157652&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21854281%26dopt%3DAbstract Conclusions: Ignoring site effects is not a viable option in multi-site clinical trials. There are advantages and disadvantages to the fixed effect and random effect approaches to modeling site effects. Scientific Significance: The distinction between efficacy trials and effectiveness trials is rarely sharp. The choice between random effect and fixed effect statistical modeling can provide different benefits depending on the goals of the study. PMID: 21854281 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5157652 Fri, 26 Aug 2011 04:57:00 +0100 5157652 http://www.medworm.com/index.php?rid=5157651&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21854282%26dopt%3DAbstract Conclusion: OROS-MPH benefit varied by site for reducing ADHD symptoms but not for improving smoking abstinence. Scientific Significance: Assessment of site-type effects can indicate the generalizability of findings from multisite trials and should be routinely incorporated in the design of multisite trials. PMID: 21854282 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5157651 Fri, 26 Aug 2011 04:56:56 +0100 5157651 http://www.medworm.com/index.php?rid=5157650&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21854283%26dopt%3DAbstract Conclusion: This article describes considerations for selecting research sites and identifies specific strategies to employ when selecting community-based sites for participation in clinical trials. PMID: 21854283 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5157650 Fri, 26 Aug 2011 04:56:51 +0100 5157650 http://www.medworm.com/index.php?rid=5157649&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21854284%26dopt%3DAbstract Conclusion: The review demonstrates the process by which research and practice have been blended in protocol development, exemplifying the underlying principle of bidirectionality, a key element in the success of the NIDA CTN. Scientific Significance: Bidirectional partnerships as derived in the CTN, employing a hybrid model of efficacy-effectiveness research, are capable of designing and implementing protocols that are both methodologically rigorous and clinically meaningful, thus increasing likelihood of adoption and eventual improvement in public health. PMID: 21854284 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5157649 Fri, 26 Aug 2011 04:56:47 +0100 5157649 http://www.medworm.com/index.php?rid=5157648&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21854285%26dopt%3DAbstract Conclusion: Many of the issues arising in the design of this study will be relevant to future studies of interventions for addictions in medical settings. Scientific Significance: Optimal trial design is critical to determining how best to integrate substance abuse interventions into medical care. PMID: 21854285 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5157648 Fri, 26 Aug 2011 04:56:42 +0100 5157648 http://www.medworm.com/index.php?rid=5157647&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21854286%26dopt%3DAbstract Conclusion: In CTN trials, the relationship between assessment burden on participants and length of trial, on the one hand, and recruitment and retention, on the other, is not as strong and direct as expected. Other factors must impinge on the conduct of the trial to influence trial participation. Scientific Significance: Researchers may deem slightly more justifiable to permit inclusion of some of the design features that previously were assumed to have a strong, negative influence on recruitment and retention, and should consider other strategies that may have a stronger, more direct effect on trial participation. PMID: 21854286 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5157647 Fri, 26 Aug 2011 04:56:38 +0100 5157647 http://www.medworm.com/index.php?rid=5157646&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21854287%26dopt%3DAbstract Conclusions and Scientific Significance: Standardized patient walkthroughs capture issues with study procedures previously unidentified with didactic training or unscripted rehearsals. Clinical trials within the National Drug Abuse Treatment Clinical Trials Network are conducted in addiction treatment centers that vary on multiple dimensions. Based on walkthrough observations, the national protocol team and local site leadership modify standardized operating procedures and resolve cross-site problems prior to recruiting study participants. The standardized patient walkthrough improves consistency across study sites and reduces potential site variation in study outcomes. PMID: 21854287 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5157646 Fri, 26 Aug 2011 04:56:34 +0100 5157646 http://www.medworm.com/index.php?rid=5157645&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21854288%26dopt%3DAbstract Conclusion: Comparison of the previous reporting strategies used in SUD trials to the new strategy demonstrates a more consistent safety system with a reduction in safety reporting burden while maintaining appropriate safety monitoring. Scientific Significance: Safety assessments should be tailored to the participant risks based on the trial intervention. The current strategies could be applied to safety assessments across all clinical trials in SUDs. PMID: 21854288 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5157645 Fri, 26 Aug 2011 04:56:29 +0100 5157645 http://www.medworm.com/index.php?rid=5157644&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21854289%26dopt%3DAbstract Conclusions and Scientific Significance: This article illustrates principles of covariation for baseline and the baseline-by-treatment interaction in nontechnical graphical terms, and discusses examples from clinical trials. Implications for the design and analysis of clinical trials are discussed, and it is argued that covariation for baseline severity of the outcome measure and testing of the baseline-by-treatment interaction should be considered for inclusion in the primary outcome analyses of treatment effectiveness trials of substantial size. PMID: 21854289 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5157644 Fri, 26 Aug 2011 04:56:24 +0100 5157644 http://www.medworm.com/index.php?rid=5157643&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21854290%26dopt%3DAbstract Conclusions and Scientific Significance: Final week dose groups differed in demographic and drug use characteristics, and the group receiving the largest final week dose had the highest rate of continued opioid use. These findings may contribute to the development of clinical guidelines regarding buprenorphine dose in the treatment of opioid dependence; however, further investigations that include random assignment to dose by baseline characteristics are needed. PMID: 21854290 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5157643 Fri, 26 Aug 2011 04:56:19 +0100 5157643 http://www.medworm.com/index.php?rid=5157642&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21854291%26dopt%3DAbstract Conclusion: Study findings document AUD comorbidity as a fairly common diagnostic feature of primary stimulant misusers, and suggest it is a pervasive influence on the pre-treatment psychosocial functioning of cocaine misusers. Scientific Significance: This study demonstrates the utility of CTN common assessment battery for secondary analysis projects, though challenges noted during its conduct highlight the value of consistent data collection and documentation within and across CTN trials. PMID: 21854291 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5157642 Fri, 26 Aug 2011 04:56:14 +0100 5157642 http://www.medworm.com/index.php?rid=5157641&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21854292%26dopt%3DAbstract Conclusions and Scientific Significance: During future efforts to improve SC treatments among drug- and alcohol-dependent patients, consideration should be given to adequate treatment to reduce the severity of the primary drug or alcohol problem, tailoring treatments for patients with greater severity of smoking and of the primary substance problem, and culturally sensitive interventions. Analysis of predictors of outcome may be a useful tool for treatment development. PMID: 21854292 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5157641 Fri, 26 Aug 2011 04:56:08 +0100 5157641 http://www.medworm.com/index.php?rid=5157672&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21851195%26dopt%3DAbstract Conclusions: The results suggest that DCS may temporarily augment cue-elicited craving for alcohol. Scientific Significance: As in an earlier study with cocaine-dependent individuals, DCS appears to exhibit a different profile in problem drinkers to those with anxiety disorders. Dose, timing, arousal, and treatment motivation as considerations are discussed, as are methodological considerations and the need for additional studies in this area. PMID: 21851195 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5157672 Wed, 17 Aug 2011 23:00:00 +0100 5157672 http://www.medworm.com/index.php?rid=5157671&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21851200%26dopt%3DAbstract Conclusion: While causal inferences cannot be made, these results suggest that the majority of people continue to drink, even after being treated for alcohol problems. Nonetheless, variation may exist depending on the form of treatment a person receives. More research is needed regarding long-term levels of abstinence after individuals receive treatment. PMID: 21851200 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5157671 Wed, 17 Aug 2011 23:00:00 +0100 5157671 http://www.medworm.com/index.php?rid=5157670&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21851201%26dopt%3DAbstract Conclusions: By assessing these parental characteristics, clinicians may be able to assess children who are at risk for impairment and, in turn, may be in need of mental health services. Due to limitations of this study, further evaluation is needed. PMID: 21851201 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5157670 Wed, 17 Aug 2011 23:00:00 +0100 5157670 http://www.medworm.com/index.php?rid=5157669&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21851202%26dopt%3DAbstract Conclusion/Scientific Significance: MAP-Engage offers an alternative approach to address lack of attendance to outpatient treatment appointments post discharge that is relatively low in staff reliance. PMID: 21851202 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5157669 Wed, 17 Aug 2011 23:00:00 +0100 5157669 http://www.medworm.com/index.php?rid=5157668&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21851203%26dopt%3DAbstract Conclusions and Scientific Significance: Although a number of limitations must be taken into account, this study provides some preliminary evidence that cognitive function may be more impaired in patients under heroin maintenance treatment than in patients receiving Bup or Met and in healthy controls. PMID: 21851203 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5157668 Wed, 17 Aug 2011 23:00:00 +0100 5157668 http://www.medworm.com/index.php?rid=5157667&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21851207%26dopt%3DAbstract Conclusions and Scientific Significance: These findings suggest differing profiles and patterns of cocaine use for male and female users in rural areas, supporting previous findings in urban areas of gender-based vulnerability to negative consequences of cocaine use. Further research on cocaine use in rural areas can provide insights into gender differences that can inform development and refinement of effective interventions in rural communities. PMID: 21851207 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5157667 Wed, 17 Aug 2011 23:00:00 +0100 5157667 http://www.medworm.com/index.php?rid=5141956&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21846304%26dopt%3DAbstract Conclusion: Students who had completed AlcoholEdu were less likely to present for an alcohol event than were students who partially completed or failed to take the course. Campus administrators should consider whether students who fail to complete an online alcohol course should be flagged for more focused interventions (e.g., brief motivational interview, mandatory education classes). Scientific Significance: This is the first study to show a relationship between first-year college students' non-completion of an online alcohol course and subsequent high-risk drinking that requires medical attention. PMID: 21846304 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5141956 Tue, 16 Aug 2011 23:00:00 +0100 5141956 http://www.medworm.com/index.php?rid=5141960&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21834605%26dopt%3DAbstract Conclusions: Intentional abuse of Coricidin products reported to the poison center occurred primarily among adolescents and was often associated with significant short-term clinical effects and a clear financial burden to the health-care system. Scientific Significance: This investigation demonstrates that Coricidin product abuse continues to be a problem particularly among adolescents. Parents and clinicians need to continue to be aware of these substances as drugs of abuse and curbing sales to adolescents should be considered. PMID: 21834605 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5141960 Wed, 10 Aug 2011 23:00:00 +0100 5141960 http://www.medworm.com/index.php?rid=5141959&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21834612%26dopt%3DAbstract Conclusion: Our findings indicate that reported willingness measures collected from IDUs regarding potential SIF program participation prior to its opening independently predicted later attendance even when variables that were likely determinants of willingness were adjusted for. These data suggest that willingness measures are reasonably valid tools for planning the delivery of health services among IDU populations. PMID: 21834612 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5141959 Wed, 10 Aug 2011 23:00:00 +0100 5141959 http://www.medworm.com/index.php?rid=5141958&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21834613%26dopt%3DAbstract Conclusions: Findings from this large community sample indicate that there were no subtype differences in treatment response, although there were differences in terms of substance use, antisocial behavior, readiness for treatment, and gender prior to treatment. Scientific Significance: This study is the first to report on subtype differences for treatment response for non-nicotine SUD in a comorbid ADHD-SUD population. Despite some baseline differences, both subtypes responded equally to treatment, suggesting limited relevance for subtype designation on treatment planning. PMID: 21834613 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5141958 Wed, 10 Aug 2011 23:00:00 +0100 5141958 http://www.medworm.com/index.php?rid=5141957&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21834614%26dopt%3DAbstract Conclusions/Scientific Significance: The results provide evidence that salvia use is part of a broader constellation of psychosocial and behavioral problems among youth and young adults. The accessibility, legal status, and psychoactive effects of salvia can be a potentially complicating health risk to young people, especially among those with existing substance use problems. PMID: 21834614 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5141957 Wed, 10 Aug 2011 23:00:00 +0100 5141957 http://www.medworm.com/index.php?rid=5141962&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21819309%26dopt%3DAbstract Conclusions: Findings suggest that maintaining connections with mainstream civic activities can be related to reduced health risks, including HIV risk behaviors. Scientific Significance: This study contributes to understanding the relationships between involvement in civic/political participation and health, an area in which few studies have been conducted. PMID: 21819309 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5141962 Sun, 07 Aug 2011 23:00:00 +0100 5141962 http://www.medworm.com/index.php?rid=5141961&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21823899%26dopt%3DAbstract ConclusionsScientific Significance: Case management appears to be a very valuable tool in MMT programs. PMID: 21823899 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5141961 Sun, 07 Aug 2011 23:00:00 +0100 5141961 http://www.medworm.com/index.php?rid=5106146&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21797810%26dopt%3DAbstract Conclusions: A low LR to alcohol is an example of how both genes and environment can contribute to the risk for adverse alcohol outcomes. The identification of mechanisms through which LR impacts on later heavy drinking and problems can be approached in cross-sectional studies, but those may not be as sensitive as longitudinal models for identifying additional potential mediators of the LR-to-outcome relationship. PMID: 21797810 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5106146 Thu, 28 Jul 2011 23:00:00 +0100 5106146 http://www.medworm.com/index.php?rid=5106145&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21797811%26dopt%3DAbstract Authors: Karam-Hage M, Strobbe S, Robinson JD, Brower KJ We conducted a double-blind pilot study involving 11 alcohol- and nicotine-dependent patients randomized to receive either bupropion or placebo. Four of six patients on bupropion and one of five patients on placebo were abstinent from smoking at the end of medication phase. Those in the bupropion group reported significantly less craving (p < .02) and less exposure to cigarette smoke over time (expired carbon monoxide; p < .01). There were no serious adverse events and no main effects of medication group on either per subject or total number of adverse events. All those who completed treatment remained abstinent from alcohol. PMID: 21797811 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Al... The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5106145 Thu, 28 Jul 2011 23:00:00 +0100 5106145 http://www.medworm.com/index.php?rid=5106144&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21797813%26dopt%3DAbstract Conclusions: The e-therapy program successfully attracted clients who were different from those who were represented in regular face-to-face alcohol treatment services. This indicates that e-therapy decreases the barriers to treatment facilities and enhances the accessibility. However, the e-therapy population changed over time. Although the e-therapy program still reached an important new group of clients in 2008-2009, this group showed more overlap with the traditional face-to-face group of clients probably as a result of improved acceptance of e-therapy in the general population. Scientific Significance: Although e-therapy seems to be better accepted in the general population, anonymous treatment seems necessary to reach a broader range of problem drinkers. PMID: 21797813 [PubMed - ... The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5106144 Thu, 28 Jul 2011 23:00:00 +0100 5106144 http://www.medworm.com/index.php?rid=5106143&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21797814%26dopt%3DAbstract Conclusion: It may be worthwhile for administrators of violence programs to pay particular attention to substance abuse among their clients and in their community's environment, especially if older persons are involved. Scientific Significance: Measures of documented elder abuse at the county level are minimal. To be able to associate substance abuse with elder abuse is a significant finding, realizing that the substance abuse can be by the victim or the perpetrator of elder abuse. PMID: 21797814 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5106143 Thu, 28 Jul 2011 23:00:00 +0100 5106143 http://www.medworm.com/index.php?rid=5106142&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21797815%26dopt%3DAbstract Conclusions: Patients with severe and very severe alcohol misuse had a twofold increased risk of hospital admission for trauma compared to drinkers without alcohol misuse. Scientific Significance: Alcohol screening scores could be used to provide feedback to patients regarding risk of trauma-related hospitalization. Findings could be used by providers during brief alcohol-related interventions with patients with alcohol misuse. PMID: 21797815 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5106142 Thu, 28 Jul 2011 23:00:00 +0100 5106142 http://www.medworm.com/index.php?rid=5106141&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21797816%26dopt%3DAbstract Conclusion: Rimonabant 20 or 40 mg did not significantly increase plasma cortisol concentrations, consistent with an absence of antagonist-elicited cannabis withdrawal. Scientific Significance: Rimonabant doses >40 mg might elicit cortisol changes, confirming a role for CB1 receptors in modulating the HPA axis in humans. PMID: 21797816 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5106141 Thu, 28 Jul 2011 23:00:00 +0100 5106141 http://www.medworm.com/index.php?rid=5011307&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21702726%26dopt%3DAbstract Conclusions: Compared to the original model, this new three-factor model of the IP is shorter, has stronger internal reliability, and is a better predictor of alcohol use over time. It is strongly recommended that researchers continue to explore the utility of this new model. PMID: 21702726 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5011307 Sun, 26 Jun 2011 23:00:00 +0100 5011307 http://www.medworm.com/index.php?rid=5058825&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21699349%26dopt%3DAbstract Conclusions: When introducing efavirenz or nevirapine to patients undergoing methadone treatment, withdrawal symptoms should be monitored, especially those such as insomnia, vomiting, or nausea. Methadone plasma trough and peak measurements can be of value in preventing unnecessary side effects of HAART. PMID: 21699349 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5058825 Wed, 22 Jun 2011 23:00:00 +0100 5058825 http://www.medworm.com/index.php?rid=5058824&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21699362%26dopt%3DAbstract Conclusions: Need-service matching contributes to improved health and social outcomes when longitudinal assessments of treatment outcomes are used to evaluate treatment effectiveness. Scientific Significance: Study findings document the value of targeted services for achieving success in health and social functioning in comprehensive substance abuse treatment. PMID: 21699362 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=5058824 Wed, 22 Jun 2011 23:00:00 +0100 5058824 http://www.medworm.com/index.php?rid=4763152&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21453192%26dopt%3DAbstract Conclusions: Further research is needed to understand and track the elevated mortality associated with illegal drug use and the correlates of drug-poisoning deaths. PMID: 21453192 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4763152 Fri, 29 Apr 2011 11:30:35 +0100 4763152 http://www.medworm.com/index.php?rid=4763151&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21453193%26dopt%3DAbstract Conclusion: Significant differences in the pattern of alcohol use and related problems exist among the students of various cultural groups - the Slavs and Arabs in Minsk, Belarus. Scientific significance: This is the first empirical study to investigate the prevalence of alcohol use and related problems among the Arab and Slav students in Belarus. PMID: 21453193 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4763151 Fri, 29 Apr 2011 11:30:31 +0100 4763151 http://www.medworm.com/index.php?rid=4763150&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21453194%26dopt%3DAbstract Conclusion: Heroin addiction is associated with decreased plasma concentrations of HDL-C, apoA-I, apoB, and increased TGL concentrations. In heroin addicts, HDL-C concentrations are significantly associated with the apoB/apoA-I index, which correlates to all lipid fractions and is a stronger predictor of metabolic syndrome lipid profile in heroin addicts. PMID: 21453194 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4763150 Fri, 29 Apr 2011 11:30:27 +0100 4763150 http://www.medworm.com/index.php?rid=4763149&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21517706%26dopt%3DAbstract Conclusion: The data generally confirm the hypothesis concerning mediating roles for religiosity and marriage. Scientific Significance: Confirmation that marriage and religiosity can protect adults against co-occurring substance abuse and psychological distress potentially provides the information necessary to better target health policy and interventions that serve to further enhance the population's mental health. PMID: 21517706 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4763149 Mon, 25 Apr 2011 23:00:00 +0100 4763149 http://www.medworm.com/index.php?rid=4763148&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21517708%26dopt%3DAbstract Conclusions and scientific significance: These findings underscore the need to assess youth alcohol consumption at the brand level and the potential value of such data in better understanding underage youth drinking behavior and the factors that influence it. PMID: 21517708 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4763148 Mon, 25 Apr 2011 23:00:00 +0100 4763148 http://www.medworm.com/index.php?rid=4763147&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21517709%26dopt%3DAbstract Conclusions: The seriousness of health outcomes associated with tampering with POs warrants the development of PO formulations that prevent or deter tampering. PMID: 21517709 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4763147 Mon, 25 Apr 2011 23:00:00 +0100 4763147 http://www.medworm.com/index.php?rid=4763146&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21517711%26dopt%3DAbstract Conclusion: Sibling pairs in which the older sibling has substance use and the younger sibling has ADHD exist. Such younger siblings can be recruited into a treatment study. The design may shed light on the pathogenesis and prevention of SUD complications from ADHD and theoretically other SUD comorbidities. PMID: 21517711 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4763146 Mon, 25 Apr 2011 23:00:00 +0100 4763146 http://www.medworm.com/index.php?rid=4763145&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21517712%26dopt%3DAbstract Conclusions and Scientific Significance: The substance use outcomes may suggest that substance-dependent depressed adults with poorer neuropsychological functioning should be offered ICBT over TSF. These individuals may be less able to develop and use novel coping skills for managing substance use and depressive symptoms on their own without formal structured training in cognitive and behavioral skills provided in ICBT. PMID: 21517712 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4763145 Mon, 25 Apr 2011 23:00:00 +0100 4763145 http://www.medworm.com/index.php?rid=4655242&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21438798%26dopt%3DAbstract Conclusions: This study found that the majority of heroin-dependent patients reported poor sleep quality. Depression, smoking, drinking, and long-term drug use were associated with poor sleep quality in heroin-dependent individuals. Scientific significance: Despite the fact that this study collected data only using self-report measures, focused only on heroin-dependent patients, and did not include long-term follow-up study, given the potential link between poor sleep quality and relapse, factoring in this link is an important consideration as part of a comprehensive heroin-dependent treatment program. PMID: 21438798 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4655242 Sun, 27 Mar 2011 23:00:00 +0100 4655242 http://www.medworm.com/index.php?rid=4655241&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21438799%26dopt%3DAbstract Conclusions: An RP component can be effective in increasing abstinence rates among post-program heroin-dependent individuals and may help reduce anxiety and improve self-esteem and self-efficacy during and following treatment. Scientific Significance: This study suggests RP as a potentially effective component of treatment for heroin addicts. PMID: 21438799 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4655241 Sun, 27 Mar 2011 23:00:00 +0100 4655241 http://www.medworm.com/index.php?rid=4655240&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21438849%26dopt%3DAbstract Conclusions and Scientific Significance: This study further elucidates the effects of TPV/r on glucuronidation. The current evaluation of glucuronide metabolites of BUP and norBUP are suggestive of combined inhibition of Uridine diphosphate (UDP)-glucuronosyltransferase of the 1A family and cytochrome P450 3A4 that spares UGT2B7 leading to a shunting of BUP away from production of norBUP and toward BUP-3G as seen by a statistically significant increase in the AUC of BUP-3G. PMID: 21438849 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4655240 Sun, 27 Mar 2011 23:00:00 +0100 4655240 http://www.medworm.com/index.php?rid=4655243&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21413914%26dopt%3DAbstract Conclusion: Heroin users attended MMT programs irregularly and their periods of attendance significantly declined by duration of the time they stayed in the treatment program. Additional interventions should be employed to help patients adhere to this long-term treatment program. PMID: 21413914 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4655243 Fri, 18 Mar 2011 00:00:00 +0100 4655243 http://www.medworm.com/index.php?rid=4655245&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21410417%26dopt%3DAbstract Conclusion/Significance: These results suggest that mindfulness deficits may be common in the substance using population, that there may be sub-groups in which these deficits are more pronounced, and that they may be a suitable focus of SUD treatment. These findings lend support to the ongoing development of mindfulness-based treatments for SUDs, and suggest that particular sub-groups may benefit more than others. Future research can aim at clarifying these deficits, and at elucidating their clinical relevance. PMID: 21410417 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4655245 Thu, 17 Mar 2011 00:00:00 +0100 4655245 http://www.medworm.com/index.php?rid=4655244&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21410418%26dopt%3DAbstract Conclusion and clinical significance: Results suggest that treatment of male partners is feasible and efficacious in the short term but modifications to the intervention are needed to sustain results. PMID: 21410418 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4655244 Thu, 17 Mar 2011 00:00:00 +0100 4655244 http://www.medworm.com/index.php?rid=4593075&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21381865%26dopt%3DAbstract Authors: PMID: 21381865 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4593075 Mon, 07 Mar 2011 00:00:00 +0100 4593075 http://www.medworm.com/index.php?rid=4414285&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21250831%26dopt%3DAbstract Conclusion: The results of this study indicate that the level of death anxiety is high, in general, among drug abusers and that being divorced, not actively practicing a religious faith, having at least 1-10 years or more than 20 years history of drug abuse, and smoking at least 20 or more cigarettes per day significantly increases the level of death anxiety. PMID: 21250831 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4414285 Fri, 21 Jan 2011 00:00:00 +0100 4414285 http://www.medworm.com/index.php?rid=4349941&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21219255%26dopt%3DAbstract Conclusion: CSOs experience frequent problems in a wide range of life domains and the types of difficulties they experience appear to differ based on type of relationship, gender, and their living arrangement relative to the SUI. Scientific Significance: This investigation expands our understanding of the specific problems that CSOs face. The findings have important implications for treatment and health policy regarding these individuals. PMID: 21219255 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4349941 Tue, 11 Jan 2011 00:00:00 +0100 4349941 http://www.medworm.com/index.php?rid=4349940&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21219256%26dopt%3DAbstract Conclusions: Approximately, 35% of patients who met current DSM-IV criteria for alcohol dependence reported no interest (or were unsure) in alcoholism treatment despite being engaged in treatment-seeking for another psychiatric disorder. Scientific Significance: These findings extend previous epidemiological studies documenting treatment-seeking patterns for alcoholism by identifying clinical features associated with interest in treatment for this disorder among psychiatric outpatients. PMID: 21219256 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4349940 Tue, 11 Jan 2011 00:00:00 +0100 4349940 http://www.medworm.com/index.php?rid=4349939&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21219257%26dopt%3DAbstract Conclusions and scientific significance: In our study, SE intensity was not influenced by the use of cannabis. With regard to familial data, this is the first study to explore the relationship between SE and the presence of psychiatric problems in first-degree relatives. The association between FCQ intensity and psychiatric familial load may confirm the independence of these phenomena from the use of cannabis. PMID: 21219257 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4349939 Tue, 11 Jan 2011 00:00:00 +0100 4349939 http://www.medworm.com/index.php?rid=4349938&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21219260%26dopt%3DAbstract Conclusion: The results indicate that the learned brain response of former heroin addicts to drug-related stimuli may persist despite long-term methadone maintenance treatment. PMID: 21219260 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4349938 Tue, 11 Jan 2011 00:00:00 +0100 4349938 http://www.medworm.com/index.php?rid=4349937&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21219261%26dopt%3DAbstract Conclusions: This pilot study points toward the need for a double-blind, placebo-controlled amphetamine withdrawal paradigm in humans where changes in sleep, cognitive function, and withdrawal measures can be explored more fully. Scientific significance: This study extends the literature by pointing toward a methamphetamine withdrawal syndrome that includes alterations in measures of sleep quality and refreshed sleep, early improvement in depression and anxiety symptoms, most striking during the first week, but persisting into the second week. PMID: 21219261 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4349937 Tue, 11 Jan 2011 00:00:00 +0100 4349937 http://www.medworm.com/index.php?rid=4349936&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21219262%26dopt%3DAbstract Conclusions: Results of this pilot study support the use of onsite immunoassay screening cups as an assessment and outcome measure in adults with serious mental illness. Scientific significance: Data suggest that onsite urinalysis screenings may be a helpful assessment tool for measuring clinical and research outcomes. PMID: 21219262 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4349936 Tue, 11 Jan 2011 00:00:00 +0100 4349936 http://www.medworm.com/index.php?rid=4349942&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21204739%26dopt%3DAbstract Conclusions: Cocaine-dependent subjects showed attentional bias to cocaine-related words, increased impulsivity, and poor inhibitory control compared with controls. The attentional bias was associated with inhibitory control in cocaine-dependent subjects but not in control subjects. Scientific Significance: Our findings suggest that cocaine-dependent subjects with poor inhibitory control may show higher attentional bias to cocaine-related words compared with controls and those with better inhibitory control. PMID: 21204739 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4349942 Wed, 05 Jan 2011 00:00:00 +0100 4349942 http://www.medworm.com/index.php?rid=4349943&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21192125%26dopt%3DAbstract Conclusion: Naltrexone induction and maintenance in newly abstinent opioid-dependent individuals does not appear to be associated with worsening of depression; however, it may be associated with sleep impairment early in treatment. PMID: 21192125 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4349943 Thu, 30 Dec 2010 00:00:00 +0100 4349943 http://www.medworm.com/index.php?rid=4349944&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21189096%26dopt%3DAbstract Conclusions: Despite limited effort, and despite the severe situation of intravenous heroin users, mobile telephone contact can be used with heavy drug users in the present setting. PMID: 21189096 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4349944 Wed, 29 Dec 2010 00:00:00 +0100 4349944 http://www.medworm.com/index.php?rid=4281679&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21171933%26dopt%3DAbstract Conclusions and Scientific Significance: Untreated alcohol dependence, particularly for released HIV-infected prisoners, has negative consequences both for the individual and society and requires a concentrated effort and rethinking of our existing approaches for this vulnerable population. PMID: 21171933 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4281679 Tue, 21 Dec 2010 00:00:00 +0100 4281679 http://www.medworm.com/index.php?rid=4281681&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21142705%26dopt%3DAbstract Conclusion: Findings suggest more men report the use of alcohol and "street" drugs, including heroin, crack cocaine, methamphetamine, marijuana, and hallucinogens. Furthermore, males report the use of alcohol, marijuana, and hallucinogens at a significantly younger age. Scientific Significance: Understanding gender differences in substance use as well as other differences among individuals living in rural Appalachia presents important opportunities to incorporate this knowledge into substance abuse early intervention, prevention, and treatment efforts. PMID: 21142705 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4281681 Fri, 10 Dec 2010 00:00:00 +0100 4281681 http://www.medworm.com/index.php?rid=4281680&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21142706%26dopt%3DAbstract Conclusion: MA-dependent individuals have abnormalities in prolactin regulation, which is not likely due to alterations in pituitary dopamine D(2) receptor availability. Scientific significance: MA dependence is associated with elevated prolactin levels, which may contribute to medical comorbidity in afflicted individuals. PMID: 21142706 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4281680 Fri, 10 Dec 2010 00:00:00 +0100 4281680 http://www.medworm.com/index.php?rid=4281682&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21142433%26dopt%3DAbstract Conclusions: The MDQ reports low specificity in detecting BSD among SUD populations. Scientific Significance: Physicians should question individuals on substance use behaviors if BSD is suspected due to high rates of comorbidity and diagnostic challenges. PMID: 21142433 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4281682 Wed, 08 Dec 2010 00:00:00 +0100 4281682 http://www.medworm.com/index.php?rid=4253550&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21128875%26dopt%3DAbstract Conclusions and Scientific Significance: The results for the study point out the need for possible specialized treatments and a need to consider how motivational elements may be addressed during the intake assessment to aid in decreasing refusal rates. Additionally, the results point toward a need for consideration of family system approaches when working with FTC participants as well as the need for further work with motivational elements and drug court participants. PMID: 21128875 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4253550 Mon, 06 Dec 2010 00:00:00 +0100 4253550 http://www.medworm.com/index.php?rid=4253549&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21128876%26dopt%3DAbstract Conclusion: This work extends existing findings of increased delay-discounting among substance-dependent individuals to homeless, substance-dependent, non-treatment seeking MSM. Scientific Significance: A better understanding of the prevalence of delay-discounting type behaviors among homeless, substance-dependent MSM can be used to inform the development of tailored substance abuse interventions for this high-risk population. PMID: 21128876 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4253549 Mon, 06 Dec 2010 00:00:00 +0100 4253549 http://www.medworm.com/index.php?rid=4253548&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21128877%26dopt%3DAbstract Conclusions: Recovering alcoholics started regular alcohol consumption prior to cigarette smoking and coffee drinking. Scientific Significance: In AA participants, coffee does not precede initiation of regular smoking or alcohol drinking as might be anticipated for a gateway drug. PMID: 21128877 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4253548 Mon, 06 Dec 2010 00:00:00 +0100 4253548 http://www.medworm.com/index.php?rid=4203403&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21091162%26dopt%3DAbstract Conclusion and Scientific Significance: This is the first study to demonstrate improved emotion regulation in BPD patients treated with DBT and to show that improved emotion regulation can account for increased behavioral control in BPD patients. Significance and future research: Emotion regulation assessment is recommended for future studies to further clarify the etiology and maintenance of disorders associated with emotional dysregulation such as BPD and substance dependence and to further explore emotion regulation as a potential mechanism of change for clinical interventions. PMID: 21091162 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4203403 Mon, 22 Nov 2010 00:00:00 +0100 4203403 http://www.medworm.com/index.php?rid=4203402&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21091174%26dopt%3DAbstract Conclusions and Scientific Significance: No major abnormalities of iron metabolism are seen in patients with chronic alcohol ingestion besides the well-known macrocytic anemia. Iron overload is relatively frequent and observed in 9% of cases. No differences in vitamin B12 and folate levels were found between individuals with alcohol dependence and social drinkers. PMID: 21091174 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4203402 Mon, 22 Nov 2010 00:00:00 +0100 4203402 http://www.medworm.com/index.php?rid=4203406&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21090958%26dopt%3DAbstract Conclusion: The presence of elevated AS is related to greater illicit use of sedatives in women but not in men. Women may be more susceptible to seek sedatives as a means of coping with unpleasant, anxious sensations. PMID: 21090958 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4203406 Fri, 19 Nov 2010 00:00:00 +0100 4203406 http://www.medworm.com/index.php?rid=4203405&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21090959%26dopt%3DAbstract Conclusion: Longitudinal measurement of motivation can be a useful clinical tool to understand later substance use problems. Scientific significance: Given the mixed findings from prior studies on the effects of baseline motivation, a shift toward examining longitudinal measures of motivation at proximal and temporal intervals is indicated. PMID: 21090959 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4203405 Fri, 19 Nov 2010 00:00:00 +0100 4203405 http://www.medworm.com/index.php?rid=4203404&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21090960%26dopt%3DAbstract Conclusion and Scientific Significance: Results indicate a need to further explore the role of fatherhood for men with co-occurring substance abuse and IPV and development of specialized treatments that may improve treatment outcomes for fathers. PMID: 21090960 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4203404 Fri, 19 Nov 2010 00:00:00 +0100 4203404 http://www.medworm.com/index.php?rid=4090845&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20955106%26dopt%3DAbstract Conclusion: These data suggest that the trading of sex for methamphetamine may be a primary source of new HIV infections within and outside of the MSM community, necessitating targeted interventions with this vulnerable subgroup. PMID: 20955106 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4090845 Mon, 18 Oct 2010 23:00:00 +0100 4090845 http://www.medworm.com/index.php?rid=4090844&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20955107%26dopt%3DAbstract Conclusions and Scientific Significance: In doses higher than 8 mg daily, buprenorphine is an appropriate treatment for opiate craving. More research with rigorous methodology is needed to study the effect of buprenorphine on heroin craving. Also more studies are needed to directly compare buprenorphine and methadone with regard to their effects on heroin craving. PMID: 20955107 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4090844 Mon, 18 Oct 2010 23:00:00 +0100 4090844 http://www.medworm.com/index.php?rid=4090846&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20942726%26dopt%3DAbstract Conclusions and Scientific Significance: The ITRS appears to be a valid instrument for measuring therapist MI adherence and competence within an assessment intake. PMID: 20942726 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4090846 Wed, 13 Oct 2010 23:00:00 +0100 4090846 http://www.medworm.com/index.php?rid=4066071&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20936990%26dopt%3DAbstract Conclusion: At treatment completion, both groups showed a reduction in physical abuse and alcohol abuse. Caucasian men showed a reduction in their use of verbal abuse, but African-American men did not. Scientific Significance: Substance dependent African-American male IPV offenders may benefit from interventions that thoroughly target communication skills in addition to issues of substance abuse and IPV to reduce use of verbal abuse and improve treatment outcomes among African American men. PMID: 20936990 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4066071 Mon, 11 Oct 2010 23:00:00 +0100 4066071 http://www.medworm.com/index.php?rid=4066070&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20936991%26dopt%3DAbstract Conclusions and Scientific Significance: The existing data suggest lower prevalence of overweight and obesity among young adult cannabis users. Further research is needed to examine the mechanism of this association. PMID: 20936991 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=4066070 Mon, 11 Oct 2010 23:00:00 +0100 4066070 http://www.medworm.com/index.php?rid=3827386&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20678027%26dopt%3DAbstract Authors: PMID: 20678027 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=3827386 Mon, 02 Aug 2010 23:00:00 +0100 3827386 http://www.medworm.com/index.php?rid=3827385&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20678028%26dopt%3DAbstract Conclusions: This small study suggests that there are few robust associations between demographic characteristics and cannabis withdrawal. Future studies with larger samples are needed. Significance: Attention to physical withdrawal symptoms in women may help promote abstinence. PMID: 20678028 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=3827385 Mon, 02 Aug 2010 23:00:00 +0100 3827385 http://www.medworm.com/index.php?rid=3827387&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20673166%26dopt%3DAbstract Conclusions: High rates of service use and barriers were observed for all levels of heroin involvement. These findings underscore the importance of improving access to services for this group, even when full criteria for a drug disorder is not met. Integration of motivational approaches is also needed within the most common services used. Scientific Significance: To our knowledge, this is the first study to describe patterns and correlates of service use using a nationally representative community sample of heroin users. PMID: 20673166 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=3827387 Sun, 01 Aug 2010 23:00:00 +0100 3827387 http://www.medworm.com/index.php?rid=3806224&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20666699%26dopt%3DAbstract Conclusion: The phenomenology of excessive nonpara- philic sexual disorder favors its conceptualization as an addictive behavior, rather than an obsessive-compulsive, or an impulse con- trol disorder. Moreover, the criteria that are quite close to those of addictive disorders were recently proposed for the future DSM-V in order to improve the characterization of this condition. Finally, controlled studies are warranted in order to establish clear guidelines for treatment of sexual addiction. PMID: 20666699 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=3806224 Wed, 28 Jul 2010 23:00:00 +0100 3806224 http://www.medworm.com/index.php?rid=3780157&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20645887%26dopt%3DAbstract Conclusion: CDS use was endemic in this treatment sample of adolescents and associated with a range of clinically significant comorbidities. Scientific Significance: Current findings describe an underrecognized and potentially dangerous form of substance misuse that has rarely been studied but that may be of growing importance. PMID: 20645887 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=3780157 Tue, 20 Jul 2010 23:00:00 +0100 3780157 http://www.medworm.com/index.php?rid=3684035&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20560836%26dopt%3DAbstract Conclusions: The substantial attenuation of the association of crack cocaine use with violence after adjustment suggests that the sociodemographic characteristics, psychiatric variables, and non-cocaine substance use disorders that make some individuals more likely to use crack cocaine than powder cocaine are responsible for the increased prevalence of violence observed among crack users, rather than crack itself. PMID: 20560836 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=3684035 Tue, 22 Jun 2010 11:39:27 +0100 3684035 http://www.medworm.com/index.php?rid=3684034&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20560837%26dopt%3DAbstract Conclusion: With this additional study, the literature suggests that alcohol-related attitude and behavioral differences between Greek leaders and members may be highly variable across college and university campuses. Scientific Significance: The socialization process among Greek leaders and members warrants further investigation. The current findings suggest that future research should examine the roles that campus climate and on-campus initiatives may play in the Greek socialization process. PMID: 20560837 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=3684034 Tue, 22 Jun 2010 11:39:24 +0100 3684034 http://www.medworm.com/index.php?rid=3684033&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20560838%26dopt%3DAbstract Conclusions: The comparison establishes convergent validity for the self-report data and decreased rates of alcohol-related injury. Scientific Significance: These findings support the validity in college populations of self-report data about negative consequences associated with drinking alcohol. PMID: 20560838 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=3684033 Tue, 22 Jun 2010 11:39:21 +0100 3684033 http://www.medworm.com/index.php?rid=3684032&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20560839%26dopt%3DAbstract Conclusions and Scientific Significance: These results suggest alcohol consumption may serve as an influence on smoking initiation among some college students. These results provide additional support to a growing literature linking alcohol use to smoking initiation in college student populations. Additional research is needed to determine the mechanisms that explain this relationship. PMID: 20560839 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=3684032 Tue, 22 Jun 2010 11:39:18 +0100 3684032 http://www.medworm.com/index.php?rid=3684031&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20560840%26dopt%3DAbstract Conclusions and Scientific Significance: Efforts are needed to reduce methamphetamine use and related sexual risk among adolescent females in Coloured communities and to prevent the spread of methamphetamine use in Black African communities. PMID: 20560840 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=3684031 Tue, 22 Jun 2010 11:39:15 +0100 3684031 http://www.medworm.com/index.php?rid=3684030&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20560841%26dopt%3DAbstract Conclusion: Filipino American drinkers living in SF and Honolulu have different risk and protective factors for AUD. Health professionals need to be aware of this difference when screening for factors associated with AUD among Filipino Americans. Scientific Significance: The current study revealed the importance of socioenvironmental context (location of residence) in predicting AUD among an Asian ethnic group. PMID: 20560841 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=3684030 Tue, 22 Jun 2010 11:39:12 +0100 3684030 http://www.medworm.com/index.php?rid=3684029&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20560842%26dopt%3DAbstract Conclusion: The selective increase in positive subjective effects of d-amphetamine suggests that individuals with subclinical inattention and hyperactivity symptoms may have increased vulnerability to stimulant abuse. PMID: 20560842 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=3684029 Tue, 22 Jun 2010 11:39:09 +0100 3684029 http://www.medworm.com/index.php?rid=3684028&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20560843%26dopt%3DAbstract Conclusions: Chronic heroin users can benefit from an antioxidant therapy, and the method currently presented can be used as an identification criterion. PMID: 20560843 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=3684028 Tue, 22 Jun 2010 11:39:07 +0100 3684028 http://www.medworm.com/index.php?rid=3684037&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20560821%26dopt%3DAbstract Conclusions and Scientific Significance: Proper categorization of behavioral addictions or impulse control disorders has substantial implications for the development of improved prevention and treatment strategies. PMID: 20560821 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=3684037 Sun, 20 Jun 2010 23:00:00 +0100 3684037 http://www.medworm.com/index.php?rid=3684036&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20560822%26dopt%3DAbstract Conclusions: Compulsive buying can be described as a behavioral dependence. A great deal of future research is needed to improve our understanding of compulsive buying. PMID: 20560822 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=3684036 Sun, 20 Jun 2010 23:00:00 +0100 3684036 http://www.medworm.com/index.php?rid=3677204&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20545601%26dopt%3DAbstract Conclusion: There are currently insufficient data to place some cases of "love passion" within a clinical disorder, such as "love addiction," in an official diagnostic nomenclature or to firmly classify it as a behavioral addiction or disorder of impulse control. Further clinical and scientific studies are needed to improve our understanding and treatment of this condition. For these studies, we propose new criteria for evaluating addiction to love. PMID: 20545601 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=3677204 Mon, 14 Jun 2010 23:00:00 +0100 3677204 http://www.medworm.com/index.php?rid=3677203&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20545602%26dopt%3DAbstract Conclusion: This evidence supports the notion that psycho-stimulant users have decreased sensitivity to natural reward. Significance: Computer game addicts or gamblers may show reduced dopamine response to stimuli associated with their addiction presumably due to sensitization. PMID: 20545602 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=3677203 Mon, 14 Jun 2010 23:00:00 +0100 3677203 http://www.medworm.com/index.php?rid=3677202&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20545603%26dopt%3DAbstract Conclusions and Scientific Significance: Although Internet-addicted individuals have difficulty suppressing their excessive online behaviors in real life, little is known about the patho-physiological and cognitive mechanisms responsible for Internet addiction. Due to the lack of methodologically adequate research, it is currently impossible to recommend any evidence-based treatment of Internet addiction. PMID: 20545603 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=3677202 Mon, 14 Jun 2010 23:00:00 +0100 3677202 http://www.medworm.com/index.php?rid=3677201&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20545604%26dopt%3DAbstract Conclusions and Scientific Significance: Frequent and persistent tanning may reveal itself to be a dermatologic-psychiatric disorder with carcinogenic sequelae. Multidisciplinary studies are required to determine the validity of an addiction diagnosis and to explore pharmacologic and cognitive therapeutic options for affected persons. PMID: 20545604 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=3677201 Mon, 14 Jun 2010 23:00:00 +0100 3677201 http://www.medworm.com/index.php?rid=3656172&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20536285%26dopt%3DAbstract Conclusions: Low urine creatinine is a poor screening test for detecting alcohol consumption among patients on methadone. However, a normal creatinine level has a 96.7% probability of no alcohol urine present in the urine. PMID: 20536285 [PubMed - as supplied by publisher] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=3656172 Wed, 09 Jun 2010 23:00:00 +0100 3656172 http://www.medworm.com/index.php?rid=3565583&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20465370%26dopt%3DAbstract CONCLUSION: Chronic use of opium and heroin can change serum FBS, K(+), Ca(2+), UA, and cholesterol. SCIENTIFIC SIGNIFICANCE: This study, one of few on the effects of opium on serum biochemical parameters in human subjects, has the potential to contribute to the investigation of new approaches for further basic studies. PMID: 20465370 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=3565583 Fri, 30 Apr 2010 23:00:00 +0100 3565583 http://www.medworm.com/index.php?rid=3565582&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20465371%26dopt%3DAbstract CONCLUSIONS AND SIGNIFICANCE: The TRQ may provide a useful self-report measure to discriminate between addicted patients who relapse without forewarning compared to those with a period of delay. Clinical interventions may be targeted towards different relapse styles. PMID: 20465371 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=3565582 Fri, 30 Apr 2010 23:00:00 +0100 3565582 http://www.medworm.com/index.php?rid=3565581&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20465372%26dopt%3DAbstract CONCLUSIONS: Treatment programs should consider administering the CEF to their patients at 3 months post-admission to identify patients with low satisfaction scores who may be at risk for prematurely leaving treatment. SCIENTIFIC SIGNIFICANCE: Measuring patient satisfaction during treatment may help programs meet patients' needs and improve retention. PMID: 20465372 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=3565581 Fri, 30 Apr 2010 23:00:00 +0100 3565581 http://www.medworm.com/index.php?rid=3565580&cid=s_37385_2_f&fid=37385&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20465373%26dopt%3DAbstract CONCLUSION: Given that extended methadone treatment is associated with improved outcomes while patients remain in treatment, more longitudinal studies using primary data collection are needed to fully explore factors related to retention. For the VA population specifically, further research is necessary to fully understand the relationship between race/ethnicity and treatment retention. SCIENTIFIC SIGNIFICANCE: This is the first retention study the authors are aware of that utilizes data from a nationwide, multisite, population of participants in methadone treatment. PMID: 20465373 [PubMed - in process] (Source: The American Journal of Drug and Alcohol Abuse) The American Journal of Drug and Alcohol Abuse journals http://www.medworm.com/rss/comments.php?id=3565580 Fri, 30 Apr 2010 23:00:00 +0100 3565580