MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'The American Journal of Geriatric Pharmacotherapy' source. Wed, 08 Feb 2012 16:54:29 +0100 http://www.medworm.com/index.php?rid=5627284&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22264852%26dopt%3DAbstract CONCLUSION: The similar and low rates of AEs in DSG-treated patients aged ≥65 years and <65 years and in those with and without comorbid hypertension, type 2 diabetes, or cerebrovascular or cardiovascular disease suggest that DSG treatment is generally well tolerated. PMID: 22264852 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5627284 Wed, 18 Jan 2012 05:00:00 +0100 5627284 http://www.medworm.com/index.php?rid=5627283&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22264853%26dopt%3DAbstract CONCLUSIONS: To enhance medication adherence in older adults prescribed multiple medications, medication class numbers and certain high-risk medication classes should be taken into account. Physicians should also routinely assess systemic (eg, cognition) or drug-specific characteristics (eg, side effects). PMID: 22264853 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5627283 Wed, 18 Jan 2012 05:00:00 +0100 5627283 http://www.medworm.com/index.php?rid=5627282&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22264854%26dopt%3DAbstract CONCLUSIONS: EBM medication adherence was high in this population, regardless of ADRD status. However, patients with ADRD had lower EBM use compared with those without ADRD. Low use of specific EBM medications such as β-blockers was found in both groups. Therefore, interventions targeting increased treatment with specific EBMs for CHF, even among patients with ADRD, may be of benefit and could help reduce CHF-related hospitalizations. PMID: 22264854 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5627282 Wed, 18 Jan 2012 05:00:00 +0100 5627282 http://www.medworm.com/index.php?rid=5627281&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22264855%26dopt%3DAbstract This article described a framework for improving prescribing in nursing homes (NH) by focusing on the whole facility as a system that has created a "prescribing culture." We offered this paradigm as an alternative to focused interventions that target prescribers only. We used the example of atypical antipsychotics to illustrate the approach. We also highlighted elements of the NH culture change movement that are germane to medication prescribing, and illustrated which elements of NH culture were shown to be associated with suboptimal quality of care. We concluded by describing current models, including our study funded by the Agency for Healthcare Research and Quality, to identify the best methods of disseminating evidence-based medication use guides in NHs. PMID: 22264855 [PubMed - as... The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5627281 Wed, 18 Jan 2012 05:00:00 +0100 5627281 http://www.medworm.com/index.php?rid=5627285&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22260856%26dopt%3DAbstract CONCLUSIONS: Treatment of CDI is challenging due to the limited number of drugs that have proven to be effective, concerns about antibiotic resistance, and recurring disease. The recent approval of fidaxomicin provides a new alternative. Immune therapy will likely play a greater role in the future. PMID: 22260856 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5627285 Tue, 17 Jan 2012 05:00:00 +0100 5627285 http://www.medworm.com/index.php?rid=5580282&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22226690%26dopt%3DAbstract CONCLUSIONS: AF is common in NH residents, and more than half of the residents with AF who had indications for and no contraindications against warfarin use were not prescribed either warfarin or antiplatelets, such as aspirin or clopidogrel, suggesting that antithrombotic therapy may be underused in NH residents with AF. PMID: 22226690 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5580282 Fri, 06 Jan 2012 05:00:00 +0100 5580282 http://www.medworm.com/index.php?rid=5538945&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22153848%26dopt%3DAbstract Authors: Guay DR PMID: 22153848 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5538945 Thu, 01 Dec 2011 05:00:00 +0100 5538945 http://www.medworm.com/index.php?rid=5428208&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22088796%26dopt%3DAbstract Authors: Hanlon JT, Schmader KE PMID: 22088796 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5428208 Mon, 14 Nov 2011 05:00:00 +0100 5428208 http://www.medworm.com/index.php?rid=5428210&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22078862%26dopt%3DAbstract CONCLUSIONS: Transitions across care settings introduce risk for patient harm, and medication errors are an important area for improvement during transitions. PMID: 22078862 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5428210 Fri, 11 Nov 2011 05:00:00 +0100 5428210 http://www.medworm.com/index.php?rid=5428209&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22078863%26dopt%3DAbstract CONCLUSIONS: Several population-based studies have reported significant harm associated drug interactions in elderly patients. Increased awareness and interventions aimed at reducing exposure and minimizing the risks associated with potentially harmful drug combinations are needed. PMID: 22078863 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5428209 Thu, 10 Nov 2011 05:00:00 +0100 5428209 http://www.medworm.com/index.php?rid=5428211&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22057096%26dopt%3DAbstract CONCLUSIONS: Benzodiazepines and anticholinergics have been consistently associated with impairments in functional status in the elderly. The relationships between suboptimal prescribing, antidepressants, and antihypertensives and functional status decline were mixed. Further research using established measures and methods is needed to better describe the impact of medication use on functional status in older adults. PMID: 22057096 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5428211 Fri, 04 Nov 2011 04:00:00 +0100 5428211 http://www.medworm.com/index.php?rid=5428214&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22055208%26dopt%3DAbstract CONCLUSIONS: The ability of this multifaceted study to repeatedly remind nursing staff of the importance of timely antibiotic administration contrasts with its limited academic detailing interaction with clinicians. This difference within the intervention may explain the differential impact of the intervention on antibiotic guideline adherence. PMID: 22055208 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5428214 Wed, 02 Nov 2011 04:00:00 +0100 5428214 http://www.medworm.com/index.php?rid=5428213&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22055209%26dopt%3DAbstract CONCLUSIONS: The iMAP tool provides a reliable and standardized approach for clinical pharmacists to use in the ambulatory care setting to classify MRPs and associated recommendations. Future studies will explore the predictive validity of the tool on clinical outcomes such as health care utilization. PMID: 22055209 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5428213 Wed, 02 Nov 2011 04:00:00 +0100 5428213 http://www.medworm.com/index.php?rid=5428212&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22055210%26dopt%3DAbstract CONCLUSION: Liraglutide provides effective glycemic control and is well tolerated in patients ≥65 and <65 years of age with type 2 diabetes. These data suggest that liraglutide may be a suitable treatment option for older patients who may have additional age-related complications. PMID: 22055210 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5428212 Wed, 02 Nov 2011 04:00:00 +0100 5428212 http://www.medworm.com/index.php?rid=5383469&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22047941%26dopt%3DAbstract CONCLUSIONS: In light of the potential clinical benefit and few reports of serious adverse events, vaccination in older adults is likely warranted. Prospective, well-controlled studies are needed to better quantitatively evaluate the benefit of pneumococcal vaccine in older adults. PMID: 22047941 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5383469 Mon, 31 Oct 2011 04:00:00 +0100 5383469 http://www.medworm.com/index.php?rid=5363559&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22035643%26dopt%3DAbstract CONCLUSIONS: Unlike conventionally used, standard analytic approaches, which focus on intervention impact at study end or change from baseline to study end, GMM enables maximum use of repeated data to identify unique trajectories of latent classes that are responsive to the intervention. ClinicalTrials.gov identifier: NCT00078286. PMID: 22035643 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5363559 Thu, 27 Oct 2011 04:00:00 +0100 5363559 http://www.medworm.com/index.php?rid=5363560&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22030114%26dopt%3DAbstract CONCLUSIONS: One in 10 outpatient visits by elderly persons with dementia involved prescribing medications with clinically significant anticholinergic activity. Given their adverse cognitive effects, there is a strong need to optimize anticholinergic drug prescribing in vulnerable elderly outpatients with dementia. PMID: 22030114 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5363560 Tue, 25 Oct 2011 04:00:00 +0100 5363560 http://www.medworm.com/index.php?rid=5363562&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22019005%26dopt%3DAbstract CONCLUSIONS: In this study of elderly statin patients without recent evidence of CV events, the majority of patients started on low-dose therapy and did not achieve sufficient adherence. After controlling for patient and clinical characteristics, no statistically significant difference in risk of CV event was observed based on initiation with atorvastatin versus simvastatin. PMID: 22019005 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5363562 Thu, 20 Oct 2011 04:00:00 +0100 5363562 http://www.medworm.com/index.php?rid=5363561&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22019006%26dopt%3DAbstract CONCLUSIONS: Use of the InterMED-Rx software identified elderly patients at risk for pharmacokinetic interactions and facilitated interventions aimed at reducing adverse drug events. Although consensus can be reached among pharmacists on how to intervene for many CYP450-DDI scenarios, certain situations allow for multiple intervention strategies. PMID: 22019006 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5363561 Thu, 20 Oct 2011 04:00:00 +0100 5363561 http://www.medworm.com/index.php?rid=5317309&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21993183%26dopt%3DAbstract CONCLUSIONS: High clinical awareness is required in diagnosing VPA-induced parkinsonism in the elderly due the presence of comorbid neurodegenerative conditions and the usage of antipsychotics in these patients. PMID: 21993183 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5317309 Mon, 10 Oct 2011 04:00:00 +0100 5317309 http://www.medworm.com/index.php?rid=5284273&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21962938%26dopt%3DAbstract CONCLUSIONS: Pancytopenia may not represent an absolute contraindication to continuing valproate therapy, although caution is warranted. PMID: 21962938 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5284273 Thu, 29 Sep 2011 04:00:00 +0100 5284273 http://www.medworm.com/index.php?rid=5235179&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21925959%26dopt%3DAbstract CONCLUSIONS: Based on the findings from the present study, coordination of care between community pharmacists and prescribers needs to be improved for the realization of potential beneficial effects of medication management on falls prevention. PMID: 21925959 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5235179 Fri, 16 Sep 2011 04:00:00 +0100 5235179 http://www.medworm.com/index.php?rid=5235178&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21925960%26dopt%3DAbstract CONCLUSION: Our study showed that residents were significantly more likely to have their AChEI discontinued if they were either admitted to hospice, stayed longer in hospice, or stayed longer in the nursing home. In addition, the majority of residents continued AChEI treatment until sometime during the week before death occurred. PMID: 21925960 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5235178 Fri, 16 Sep 2011 04:00:00 +0100 5235178 http://www.medworm.com/index.php?rid=5235180&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21920825%26dopt%3DAbstract CONCLUSION: Automated eGFR reporting alone, without any order entry intervention, was associated only transiently with improved dosing appropriateness for these older adults with concealed renal insufficiency. PMID: 21920825 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5235180 Tue, 13 Sep 2011 04:00:00 +0100 5235180 http://www.medworm.com/index.php?rid=5221699&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21890424%26dopt%3DAbstract CONCLUSION: Despite a fairly high overall MRSI in these patients admitted to ACE units, a substantial proportion of the prescription-medication discrepancies were associated with potential harm. PMID: 21890424 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5221699 Fri, 02 Sep 2011 04:00:00 +0100 5221699 http://www.medworm.com/index.php?rid=5160407&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21865093%26dopt%3DAbstract CONCLUSIONS: A telephone MTM program resolved significantly more MHRPs compared with a control group, but there were no significant changes in adherence and total drug costs. PMID: 21865093 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5160407 Mon, 22 Aug 2011 23:00:00 +0100 5160407 http://www.medworm.com/index.php?rid=5142971&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21849262%26dopt%3DAbstract CONCLUSION: Management of gout in the older adult involves careful selection of treatment based on potential benefits and consequences of therapy, considered in tandem with individual patient-specific characteristics. ClinicalTrials.gov identifiers NCT00549549, NCT01101035, NCT00241839, NCT01157936, NCT00997542, NCT00288158, and NCT00987415. PMID: 21849262 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5142971 Sun, 14 Aug 2011 23:00:00 +0100 5142971 http://www.medworm.com/index.php?rid=5142972&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21840265%26dopt%3DAbstract CONCLUSIONS: Improved guidelines for the diagnosis and management of UTIs in the elderly population are needed. Better techniques to evaluate and prevent catheter-associated bacteriuria and UTIs await improved diagnostic modalities and catheter technologies. Alternative methods for prophylaxis of patients who suffer from recurrent infections must be found while minimizing the risk of developing or propagating antibiotic resistance. PMID: 21840265 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5142972 Wed, 10 Aug 2011 23:00:00 +0100 5142972 http://www.medworm.com/index.php?rid=5112784&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21803659%26dopt%3DAbstract Authors: Clarke JA, Cutler M, Gong I, Schwarz UI, Freeman D, Dasgupta M The cytochrome P450 (CYP) 2D6 enzyme is involved in the metabolism of many drugs used by the elderly population. Variations in its activity can lead to altered drug response. However, few studies on the activity of this enzyme system have enrolled the elderly population. PMID: 21803659 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5112784 Sun, 31 Jul 2011 23:00:00 +0100 5112784 http://www.medworm.com/index.php?rid=5112783&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21821206%26dopt%3DAbstract Authors: Hanlon JT, Schmader KE PMID: 21821206 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5112783 Sun, 31 Jul 2011 23:00:00 +0100 5112783 http://www.medworm.com/index.php?rid=5112782&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21821207%26dopt%3DAbstract Authors: Guay DR PMID: 21821207 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5112782 Sun, 31 Jul 2011 23:00:00 +0100 5112782 http://www.medworm.com/index.php?rid=5070265&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21763214%26dopt%3DAbstract CONCLUSIONS: The initial choice among the various cholinesterase inhibitors requires consideration to adherence and cost. Consideration to differences in pharmacokinetics among these drugs provides a better understanding for the clinical practice of dose titration, identification and management of drug-related side effects, and lapses in therapy. Pharmacokinetic considerations among the various agents and formulations provide the clinician with options to enhance therapy when these agents are chosen for treatment of patients with Alzheimer-type dementia. PMID: 21763214 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5070265 Tue, 12 Jul 2011 23:00:00 +0100 5070265 http://www.medworm.com/index.php?rid=5070264&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21763215%26dopt%3DAbstract CONCLUSIONS: Medication discrepancies at the time of hospital discharge are a common occurrence for geriatric patients. Physician summaries might be the least reliable source of discharge medication lists. The number of discrepancies appears to not be associated with patient age, but rather with the number of medications at discharge. Discrepancies among medication lists are common, and the presence of a pharmacist may reduce the number that occur. PMID: 21763215 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5070264 Tue, 12 Jul 2011 23:00:00 +0100 5070264 http://www.medworm.com/index.php?rid=4972307&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21664193%26dopt%3DAbstract CONCLUSIONS: Medication-related problems were prevalent in both black and white older adults and persisted over 1 year. Blacks had more medication-related problems than whites, including higher rates of nonadherence. These findings require further study to better understand racial disparities in the quality of medication use in older adults and the impact of race on specific medication-related problems. PMID: 21664193 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4972307 Tue, 07 Jun 2011 23:00:00 +0100 4972307 http://www.medworm.com/index.php?rid=4924186&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21659006%26dopt%3DAbstract CONCLUSION: Nearly one third of elderly SNF residents had diabetes. These patients, compared with SNF residents without diabetes, had a greater comorbid burden, were prescribed more medications to treat these conditions, and had more hospitalizations. PMID: 21659006 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4924186 Mon, 06 Jun 2011 23:00:00 +0100 4924186 http://www.medworm.com/index.php?rid=4924188&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21636042%26dopt%3DAbstract Authors: Orwig D, Rickles NM, Martin LG The shifting of demographics to an aging society with multiple chronic illnesses and increased heterogeneity has created an undeniable imperative regarding the knowledge about pharmacotherapy in older patients, especially because older adults have a higher rate of medication use compared with the general population. More research on pharmacotherapy in older adults is needed to maximize not only the appropriate use of medications but also the benefits of available treatments in this historically underrepresented group. Investigators face many challenges that may greatly affect the outcomes of research on pharmacotherapy in older adults. PMID: 21636042 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4924188 Tue, 31 May 2011 23:00:00 +0100 4924188 http://www.medworm.com/index.php?rid=4924187&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21636043%26dopt%3DAbstract Authors: Guay DR PMID: 21636043 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4924187 Tue, 31 May 2011 23:00:00 +0100 4924187 http://www.medworm.com/index.php?rid=4877355&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21616722%26dopt%3DAbstract CONCLUSION: Medication discontinuation and OOP costs among beneficiaries with osteoporosis were highest for those enrolled in Part D plans with a coverage gap. Providers should be aware of potential cost-related nonadherence among Medicare beneficiaries taking osteoporosis medications. PMID: 21616722 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4877355 Tue, 24 May 2011 23:00:00 +0100 4877355 http://www.medworm.com/index.php?rid=4877356&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21602106%26dopt%3DAbstract CONCLUSION: Gabapentin-associated anorgasmia may be more common in older patients and appears to be dose dependent. PMID: 21602106 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4877356 Thu, 19 May 2011 23:00:00 +0100 4877356 http://www.medworm.com/index.php?rid=4877357&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21596626%26dopt%3DAbstract CONCLUSIONS: Among nursing home residents with dementia, conventional antipsychotic therapy, particularly short-term therapy, increased their risk of developing diabetes. Atypical antipsychotic use was not associated with an increased risk of diabetes onset. PMID: 21596626 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4877357 Mon, 16 May 2011 23:00:00 +0100 4877357 http://www.medworm.com/index.php?rid=4877358&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21570361%26dopt%3DAbstract CONCLUSION: Age should not be considered a barrier for the provision of optimal secondary prevention interventions. The available evidence supports similar and sometimes superior derived benefit from secondary preventive stroke measures in the elderly compared with that seen in younger patients. PMID: 21570361 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4877358 Tue, 10 May 2011 23:00:00 +0100 4877358 http://www.medworm.com/index.php?rid=4824543&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21565562%26dopt%3DAbstract CONCLUSIONS: This was a case of probable drug-induced parkinsonism in an elderly woman who had improvement of her depression and parkinsonism after receiving ECT. PMID: 21565562 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4824543 Mon, 09 May 2011 23:00:00 +0100 4824543 http://www.medworm.com/index.php?rid=4824544&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21550858%26dopt%3DAbstract CONCLUSIONS: The lack of a clear definition, absence of well-defined risk factors, and ambiguous clinical manifestations of psychoactive medication misuse and abuse present substantial barriers to diagnosis. A standard, age-appropriate definition could help PCPs establish a diagnosis, clarify what constitutes appropriate psychoactive medication use, define the extent of the problem, and pave the way for the development of effective screening and diagnostic tools. PMID: 21550858 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4824544 Thu, 05 May 2011 23:00:00 +0100 4824544 http://www.medworm.com/index.php?rid=4722012&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21470918%26dopt%3DAbstract CONCLUSIONS: There is no rationale for withholding bisphosphonate therapy from patients with osteoporosis, although continued use of bisphosphonates beyond a treatment period of 3 to 5 years should be reevaluated annually. In patients who have been on long-term bisphosphonate therapy, physicians should specifically solicit information of unique clinical features and consider imaging, when appropriate. PMID: 21470918 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4722012 Sun, 03 Apr 2011 23:00:00 +0100 4722012 http://www.medworm.com/index.php?rid=4722023&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21459304%26dopt%3DAbstract Authors: Peron EP, Marcum ZA, Boyce R, Hanlon JT, Handler SM This paper reviews articles from 2010 that examined medication mishaps (ie, medication errors and adverse drug events [ADEs]) in the elderly. PMID: 21459304 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4722023 Tue, 01 Feb 2011 00:00:00 +0100 4722023 http://www.medworm.com/index.php?rid=4722022&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21459305%26dopt%3DAbstract Authors: Gellad WF, Grenard JL, Marcum ZA Medication nonadherence is a common problem among the elderly. PMID: 21459305 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4722022 Tue, 01 Feb 2011 00:00:00 +0100 4722022 http://www.medworm.com/index.php?rid=4722021&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21459306%26dopt%3DAbstract Authors: Tanwani LK Most elderly patients with type 2 diabetes require, or will eventually require, insulin to achieve or maintain their glycemic goals. However, insulin therapy remains underused in this population. PMID: 21459306 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4722021 Tue, 01 Feb 2011 00:00:00 +0100 4722021 http://www.medworm.com/index.php?rid=4722020&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21459307%26dopt%3DAbstract Authors: Schiller DS, Parikh A Prostatitis is a collection of signs and symptoms that occur as a result of inflammation or swelling of the prostate gland. There are many different causes for prostatitis, including infection; occasionally no clear etiology for the inflammation is found. Effective treatment often depends on identification of the cause, but a microbiologic organism is not always detectable, especially in cases of chronic prostatitis. PMID: 21459307 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4722020 Tue, 01 Feb 2011 00:00:00 +0100 4722020 http://www.medworm.com/index.php?rid=4722019&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21459308%26dopt%3DAbstract Authors: Guénette L, Moisan J It is generally believed that elderly persons know little about the purpose of their medications. However, researchers have reported contradictory results. Moreover, little is known about which patient characteristics are associated with knowledge of a drug's purpose. PMID: 21459308 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4722019 Tue, 01 Feb 2011 00:00:00 +0100 4722019 http://www.medworm.com/index.php?rid=4722018&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21459309%26dopt%3DAbstract The objectives of this study were to describe changes in glyburide prescribing in cohorts that were and were not targeted by a risk reduction project, assess factors associated with glyburide discontinuation, and evaluate changes in glycated hemoglobin (ie, HbA(1c)) levels and rates of serious hypoglycemia. PMID: 21459309 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4722018 Tue, 01 Feb 2011 00:00:00 +0100 4722018 http://www.medworm.com/index.php?rid=4722017&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21459310%26dopt%3DAbstract Authors: Schulz RM, Porter C, Lane M, Cornman C, Branham L Community-dwelling frail elderly have an increased need for effective medication management to reside in their homes and delay or avoid admission to nursing homes. PMID: 21459310 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4722017 Tue, 01 Feb 2011 00:00:00 +0100 4722017 http://www.medworm.com/index.php?rid=4722016&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21459311%26dopt%3DAbstract Authors: Rockwood K, Walsh R, Martin E, Darvesh S Older adults are susceptible to a variety of illnesses, many of which can be treated with medications that may need to be used for the long term. Considerable attention has been paid to drugs that, in addition to their intended function, may have an anticholinergic effect that results in undesirable side effects, including impairment in cognition. Cholinesterase inhibitors are used as procholinergic drugs to improve cognitive dysfunction in Alzheimer's disease. We hypothesized that some of the drugs commonly used by older adults might, in addition to their intended function, also have procholinergic effects by virtue of inhibiting cholinesterases. PMID: 21459311 [PubMed - in process] (Source: The American Journal of Geriatric Pharma... The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4722016 Tue, 01 Feb 2011 00:00:00 +0100 4722016 http://www.medworm.com/index.php?rid=4722015&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21459312%26dopt%3DAbstract We present a case of linezolid-associated hypoglycemia in a 64-year-old diabetic patient with presumed MRSA cellulitis. PMID: 21459312 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4722015 Tue, 01 Feb 2011 00:00:00 +0100 4722015 http://www.medworm.com/index.php?rid=4722014&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21459313%26dopt%3DAbstract Authors: Wagg A PMID: 21459313 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4722014 Tue, 01 Feb 2011 00:00:00 +0100 4722014 http://www.medworm.com/index.php?rid=4722013&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21459314%26dopt%3DAbstract Authors: Wood L, Neumiller J, Setter S, Dobbins E PMID: 21459314 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4722013 Tue, 01 Feb 2011 00:00:00 +0100 4722013 http://www.medworm.com/index.php?rid=4546010&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21356501%26dopt%3DAbstract Authors: Hanlon JT, Donohue J PMID: 21356501 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4546010 Wed, 01 Dec 2010 00:00:00 +0100 4546010 http://www.medworm.com/index.php?rid=4546000&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21356502%26dopt%3DAbstract Conclusions: A search of the literature did not identify any prospective clinical trials on the treatment of SSTIs in the elderly; therefore, it is recommended to follow treatment based on the current IDSA guidelines. More research and publications are needed to establish proper selection of antimicrobial agents, treatment strategies, and duration of therapy of SSTIs in the elderly population. PMID: 21356502 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4546000 Wed, 01 Dec 2010 00:00:00 +0100 4546000 http://www.medworm.com/index.php?rid=4545999&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21356503%26dopt%3DAbstract Conclusions: Higher-quality trials evaluating the treatment of constipation in older patients are needed to create a basis for more definitive recommendations in this population. The approach to older adults with constipation should be individualized. PMID: 21356503 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4545999 Wed, 01 Dec 2010 00:00:00 +0100 4545999 http://www.medworm.com/index.php?rid=4545998&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21356504%26dopt%3DAbstract Conclusion: Experience with daptomycin in this group of older adults suggests good tolerability and clinical outcomes that are consistent with the results of other studies published to date. PMID: 21356504 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4545998 Wed, 01 Dec 2010 00:00:00 +0100 4545998 http://www.medworm.com/index.php?rid=4545996&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21356505%26dopt%3DAbstract Conclusions: Incident PIM use was high among these elderly Indiana Medicaid residents of nursing homes. Individuals who began use of a PIM were at a higher risk of hospitalization and of dying. PMID: 21356505 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4545996 Wed, 01 Dec 2010 00:00:00 +0100 4545996 http://www.medworm.com/index.php?rid=4545993&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21356506%26dopt%3DAbstract Conclusions: In this sample of Medicare beneficiaries with COPD enrolled in Part D, mean annual spending in 2006 was significantly higher for levalbuterol than for albuterol. The differences between levalbuterol and albuterol users in terms of patient characteristics, geographic region, and drug formulation/device type, coupled with the inconclusive evidence for efficacy differences in the literature, highlight the need for further comparative clinical and cost-effectiveness studies of these agents. PMID: 21356506 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4545993 Wed, 01 Dec 2010 00:00:00 +0100 4545993 http://www.medworm.com/index.php?rid=4545991&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21356507%26dopt%3DAbstract Conclusions: Physicians' reasons for not prescribing guideline-recommended drugs for heart failure are complex but can be organized into a useful taxonomy. This taxonomy may be helpful for performance-measurement and quality-improvement programs that seek to understand reasons for physicians' nonadherence to guidelines. PMID: 21356507 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4545991 Wed, 01 Dec 2010 00:00:00 +0100 4545991 http://www.medworm.com/index.php?rid=4545990&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21356508%26dopt%3DAbstract Conclusion: This was a probable case of extrapyramidal symptoms in an elderly woman who began using amiodarone while also taking amitriptyline. PMID: 21356508 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4545990 Wed, 01 Dec 2010 00:00:00 +0100 4545990 http://www.medworm.com/index.php?rid=4545989&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21356509%26dopt%3DAbstract Authors: Guay DR PMID: 21356509 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4545989 Wed, 01 Dec 2010 00:00:00 +0100 4545989 http://www.medworm.com/index.php?rid=4546019&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21335294%26dopt%3DAbstract Conclusions: For elderly patients with type 2 DM, reductions in HbA(1c) after treatment with a DPP-4 inhibitor were not significantly different from those in younger patients. Use of DPP-4 inhibitors in these studies was associated with a low risk of hypoglycemia, and these agents were weight neutral. PMID: 21335294 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4546019 Fri, 01 Oct 2010 00:00:00 +0100 4546019 http://www.medworm.com/index.php?rid=4546018&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21335295%26dopt%3DAbstract Conclusions: The elderly population appears to gain comparable benefits as does a younger population from the use of digoxin for heart failure management in terms of symptom improvement and reduction of hospitalization. In atrial fibrillation, digoxin does not control the ventricular rate as efficaciously during exercise and in high adrenergic states as do R-blockers and calcium channel blockers. The elderly have reduced elimination of digoxin, so if digoxin is to be used, the dosing strategy must be conservative and therapeutic monitoring is needed. Further clinical studies are needed to confirm the pharmacokinetic parameters of digoxin in elderly patients with heart failure and/or atrial fibrillation. PMID: 21335295 [PubMed - in process] (Source: The American Journal of Geriatric Pha... The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4546018 Fri, 01 Oct 2010 00:00:00 +0100 4546018 http://www.medworm.com/index.php?rid=4546017&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21335296%26dopt%3DAbstract Conclusions: Results of this study support the feasibility of using community pharmacies to deliver a falls-prevention program targeting high-risk older adults. Although the ITT analyses revealed no significant reduction in the rate of recurrent falls, injurious falls, or overall use of high-risk medications, individuals in the intervention group were more likely than those in the control group to discontinue use of a high-risk medication or have the dosage reduced during the 1-year follow-up period. More work is needed to evaluate the intervention using a larger sample size that provides greater power to detect clinically meaningful effects of reduction in the use of high-risk medications on preventing or reducing falls in the high-risk population. PMID: 21335296 [PubMed - in process]... The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4546017 Fri, 01 Oct 2010 00:00:00 +0100 4546017 http://www.medworm.com/index.php?rid=4546016&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21335297%26dopt%3DAbstract Conclusions: In this comparison of users and nonusers of maintenance medication for COPD, use of maintenance therapy was associated with significantly lower risks of hospitalization and rehospitalization and reduced Medicare expenditures. PMID: 21335297 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4546016 Fri, 01 Oct 2010 00:00:00 +0100 4546016 http://www.medworm.com/index.php?rid=4546014&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21335298%26dopt%3DAbstract Conclusion: None of the dosages of galantamine investigated in this study significantly altered ECG parameters or arterial blood pressure (relative to baseline) in these elderly patients with AD. PMID: 21335298 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4546014 Fri, 01 Oct 2010 00:00:00 +0100 4546014 http://www.medworm.com/index.php?rid=4546013&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21335299%26dopt%3DAbstract Conclusions: Evidence is accumulating in relation to a range of adverse outcomes associated with using multiple drugs with sedative properties. However, no studies have been conducted using>1 method to quantify the cumulative effect of taking multiple drugs with sedative properties. Each method has likely advantages and disadvantages. The usefulness of each method in clinical practice remains to be determined. The models must be validated in different populations of older people and may subsequently need to be refined. PMID: 21335299 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4546013 Fri, 01 Oct 2010 00:00:00 +0100 4546013 http://www.medworm.com/index.php?rid=4546011&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21335300%26dopt%3DAbstract Authors: Guay DR PMID: 21335300 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4546011 Fri, 01 Oct 2010 00:00:00 +0100 4546011 http://www.medworm.com/index.php?rid=4018172&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20869619%26dopt%3DAbstract Authors: Chen JJ PMID: 20869619 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4018172 Sat, 31 Jul 2010 23:00:00 +0100 4018172 http://www.medworm.com/index.php?rid=4018171&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20869620%26dopt%3DAbstract CONCLUSIONS: Various pharmacologic and nonpharmacologic strategies are available for the management of the nonmotor symptoms of PD. The challenges associated with nonmotor symptoms must not be forgotten in light of the motor symptoms of PD, and treatment of nonmotor symptoms should be encouraged. PMID: 20869620 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4018171 Sat, 31 Jul 2010 23:00:00 +0100 4018171 http://www.medworm.com/index.php?rid=4018170&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20869621%26dopt%3DAbstract CONCLUSIONS: Results of the identified studies suggested that patients with PD might benefit from long-term clozapine therapy. Results of the quetiapine studies were conflicting. However, no statistically significant difference in effectiveness was found between quetiapine and clozapine in comparative trials. The significance of the differences in treatment responses between patients with dementia and those without dementia remains unclear, and it was not possible to draw conclusions for or against other atypical antipsychotics because of insufficient evidence. Further studies are needed to address the methodologic issues in the current trials and to assess safety issues in larger cohorts. PMID: 20869621 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4018170 Sat, 31 Jul 2010 23:00:00 +0100 4018170 http://www.medworm.com/index.php?rid=4018169&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20869622%26dopt%3DAbstract CONCLUSIONS: TBZ is a complicated drug in terms of its mechanism of action and its activities against the 3 major monoamines in the CNS, making it difficult to predict its efficacy and tolerability in patients with hyperkinetic movement disorders. It is associated with numerous adverse effects and several important drug-drug interactions. Much work remains to be done to determine the therapeutic potential of TBZ in the treatment of hyperkinetic movement disorders. PMID: 20869622 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4018169 Sat, 31 Jul 2010 23:00:00 +0100 4018169 http://www.medworm.com/index.php?rid=4018168&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20869623%26dopt%3DAbstract CONCLUSIONS: This study found a differential compliance and persistence across PD drug therapies. The compliance rate for rasagiline was significantly higher than that for all of the other PD medications. In addition, rasagiline and levodopa/carbidopa/entacapone were associated with significantly higher persistence rates than were the other PD medications. PMID: 20869623 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4018168 Sat, 31 Jul 2010 23:00:00 +0100 4018168 http://www.medworm.com/index.php?rid=4018167&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20869624%26dopt%3DAbstract CONCLUSIONS: Almost half of the elderly Medicare beneficiaries with PD in this study did not use any APD between 2000 and 2003. Levodopa was the most frequently used APD, either as monotherapy or in combination with other APDs. The identified determinants of APD use (age, education, prescription drug coverage, ADLs, dementia, depression, and residing in an institution) may be helpful in developing interventions for this population. PMID: 20869624 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4018167 Sat, 31 Jul 2010 23:00:00 +0100 4018167 http://www.medworm.com/index.php?rid=4018166&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20869625%26dopt%3DAbstract Authors: Bell JS, Hartikainen S PMID: 20869625 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=4018166 Sat, 31 Jul 2010 23:00:00 +0100 4018166 http://www.medworm.com/index.php?rid=3754192&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20624609%26dopt%3DAbstract Conclusions: Mixed results were reported for a variety of approaches used to improve suboptimal prescribing. However, the heterogeneity of the study interventions and the various measures of suboptimal prescribing used in these studies does not allow for an authoritative conclusion based on the currently available literature. PMID: 20624609 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3754192 Mon, 31 May 2010 23:00:00 +0100 3754192 http://www.medworm.com/index.php?rid=3754191&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20624610%26dopt%3DAbstract Conclusion: In this study of older adults, no significant cost savings were found with influenza vaccines in the 3 influenza seasons examined (2002-2005) when the outcome was measured in terms of differential spending for acute and chronic respiratory conditions. PMID: 20624610 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3754191 Mon, 31 May 2010 23:00:00 +0100 3754191 http://www.medworm.com/index.php?rid=3754190&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20624611%26dopt%3DAbstract Conclusions: Most of the disabled older women in this study took >/=5 medications at baseline, potentially putting them at high risk for ADEs. Those with multimorbidity, frailty, CHF, angina, DM, COPD, cancer, and difficulty with instrumental activities of daily living are target subpopulations for polypharmacy intervention. PMID: 20624611 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3754190 Mon, 31 May 2010 23:00:00 +0100 3754190 http://www.medworm.com/index.php?rid=3754189&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20624612%26dopt%3DAbstract Conclusions: The prevalence of nonpain symptoms was low (22.0% weighted) in older nursing home hospice/palliative care patients. However, medication undertreatment of nonpain symptoms was seen in more than half of these patients. Future quality-improvement initiatives for nursing home hospice/palliative care patients are needed beyond the management of pain symptoms. PMID: 20624612 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3754189 Mon, 31 May 2010 23:00:00 +0100 3754189 http://www.medworm.com/index.php?rid=3754188&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20624613%26dopt%3DAbstract Conclusions: Analgesics were used by ~50% of community-dwelling people aged >/=75 years. However, age was not significantly associated with increased use of analgesics in multivariate analysis. The majority of analgesic drugs were used on an as-needed rather than a daily basis (76.7% vs 23.3%, respectively). Factors most significantly associated with analgesic use were female sex, living alone, poor self-rated health, and use of >/=10 nonanalgesic drugs. PMID: 20624613 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3754188 Mon, 31 May 2010 23:00:00 +0100 3754188 http://www.medworm.com/index.php?rid=3754187&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20624614%26dopt%3DAbstract Conclusions: Stronger concerns and beliefs about medicines and having more symptoms were significantly related to self-reporting of ADEs. Receiving an inappropriate medication and the number of medicines received were not significantly related. PMID: 20624614 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3754187 Mon, 31 May 2010 23:00:00 +0100 3754187 http://www.medworm.com/index.php?rid=3754186&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20624615%26dopt%3DAbstract Conclusions: Repeat medication errors in nursing homes are a common occurrence and have greater odds of being associated with harm than do nonrepeat errors. Future patient-safety research should focus on factors related to repeat errors. PMID: 20624615 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3754186 Mon, 31 May 2010 23:00:00 +0100 3754186 http://www.medworm.com/index.php?rid=3754185&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20624616%26dopt%3DAbstract Conclusions: The campaign for rational drug use in hospitalized elderly patients in India should promote pantoprazole, ceftriaxone, and atorvastatin prescribing in concordance with their indications. Interventions to reduce the high-level polypharmacy in the elderly during their stays in tertiary care hospitals in India should focus on patients with >/=3 diagnoses, angina pectoris, and/or >/=10 days of hospital stay. PMID: 20624616 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3754185 Mon, 31 May 2010 23:00:00 +0100 3754185 http://www.medworm.com/index.php?rid=3754184&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20624617%26dopt%3DAbstract Conclusion: In this case report, infusion of valproate sodium at a rate of 14 mg/min was a probable cause of hypotension in a 75-year-old man. PMID: 20624617 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3754184 Mon, 31 May 2010 23:00:00 +0100 3754184 http://www.medworm.com/index.php?rid=3534641&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20439059%26dopt%3DAbstract Authors: Hanlon JT, Schmader KE PMID: 20439059 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3534641 Wed, 31 Mar 2010 23:00:00 +0100 3534641 http://www.medworm.com/index.php?rid=3534640&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20439060%26dopt%3DAbstract CONCLUSIONS: Overall, few studies have examined the use and efficacy of alternative psychotropic formulations and delivery methods in elderly patients with BPSD, and none have specifically addressed drug-alteration and alternative-administration issues. There is no evidence to compare alternative delivery forms (eg, tablet or capsule) of a given medication in terms of efficacy or tolerability. Still, alternative methods may be the only option for treatment of some patients. Practitioners must be familiar with the range of formulations and delivery options available so that they can optimize their patients' medication regimens. More data are needed on the use of alternative formulations, delivery methods, and administration options and their limitations in this population. PMID: 2043906... The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3534640 Wed, 31 Mar 2010 23:00:00 +0100 3534640 http://www.medworm.com/index.php?rid=3534639&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20439061%26dopt%3DAbstract CONCLUSIONS: Medication discrepancies on admission and medication differences at discharge were prevalent for adult patients admitted to the general medicine, cardiology, and general surgery services in this academic teaching hospital. Medication reconciliation processes have a high potential to identify clinically important discrepancies for all patients. PMID: 20439061 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3534639 Wed, 31 Mar 2010 23:00:00 +0100 3534639 http://www.medworm.com/index.php?rid=3534638&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20439062%26dopt%3DAbstract CONCLUSIONS: Many of the unspecified medications that were identified in this study have been associated with polypharmacy in the literature. The results of this study suggest that matching home medications with indications for those medications on admission to the hospital enhanced the medication reconciliation process. Direct patient questioning by the pharmacist clarified medication use and contributed to more accurate and complete medication history taking. PMID: 20439062 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3534638 Wed, 31 Mar 2010 23:00:00 +0100 3534638 http://www.medworm.com/index.php?rid=3534637&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20439063%26dopt%3DAbstract CONCLUSION: Elderly African Americans reported that they followed physician instructions on how to take medications less frequently than did elderly whites, even after adjusting for differences in demographic characteristics, health literacy, depression, and social support. PMID: 20439063 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3534637 Wed, 31 Mar 2010 23:00:00 +0100 3534637 http://www.medworm.com/index.php?rid=3534636&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20439064%26dopt%3DAbstract CONCLUSIONS: In a group of elderly Japanese patients, 43.6% used at least one PIM over a 1-year period in this study. PIM use was associated with greater health care utilization rates and costs. PMID: 20439064 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3534636 Wed, 31 Mar 2010 23:00:00 +0100 3534636 http://www.medworm.com/index.php?rid=3534635&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20439065%26dopt%3DAbstract CONCLUSIONS: Use of calcium or calcium/vitamin D supplements was low (<60%) among this group of older Mexican Americans. Men are particularly at risk. More should be done to raise awareness regarding the benefits of calcium supplementation in this ethnic group. PMID: 20439065 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3534635 Wed, 31 Mar 2010 23:00:00 +0100 3534635 http://www.medworm.com/index.php?rid=3534634&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20439066%26dopt%3DAbstract CONCLUSION: This case report describes separate episodes of delirium probably related to treatment with levetiracetam and amiodarone in an elderly patient. PMID: 20439066 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3534634 Wed, 31 Mar 2010 23:00:00 +0100 3534634 http://www.medworm.com/index.php?rid=3375008&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20226389%26dopt%3DAbstract Authors: Hanlon JT PMID: 20226389 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3375008 Mon, 01 Feb 2010 00:00:00 +0100 3375008 http://www.medworm.com/index.php?rid=3375007&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20226390%26dopt%3DAbstract Conclusions: Vitamin D insufficiency appears to be highly prevalent among older adults. Evidence from epidemiologic studies and small clinical trials suggests an association between 25(OH)D concentrations and systolic blood pressure, risk for CV disease-related deaths, symptoms of depression, cognitive deficits, and mortality. The Women's Health Initiative Randomized Trial did not find a benefit of vitamin D supplementation on blood pressure, myocardial infarction, or mortality in postmenopausal women. PMID: 20226390 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3375007 Mon, 01 Feb 2010 00:00:00 +0100 3375007 http://www.medworm.com/index.php?rid=3375006&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20226391%26dopt%3DAbstract Conclusions: Observational studies suggest an association between use of anticonvulsant medications, reduced bone mineral density, and increased fracture risk. Randomized clinical trials are needed to guide the management of bone disease among those who use anticonvulsants. PMID: 20226391 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3375006 Mon, 01 Feb 2010 00:00:00 +0100 3375006 http://www.medworm.com/index.php?rid=3375005&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20226392%26dopt%3DAbstract Conclusion: Adherence to established guidelines, along with customization of antimicrobial therapy based on local rates and patterns of resistance and patient-specific risk factors, likely will improve the treatment outcome of elderly patients with CAP. PMID: 20226392 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3375005 Mon, 01 Feb 2010 00:00:00 +0100 3375005 http://www.medworm.com/index.php?rid=3375004&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20226393%26dopt%3DAbstract Conclusions: Despite awareness of polypharmacy and its potential consequences in older patients, results of our analysis suggest that polypharmacy remains widespread in US nursing homes. Although complex medication regimens are often necessary for nursing home residents, monitoring polypharmacy and its consequences may improve the quality of nursing home care and reduce unnecessary health care spending related to adverse events. PMID: 20226393 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3375004 Mon, 01 Feb 2010 00:00:00 +0100 3375004 http://www.medworm.com/index.php?rid=3375003&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20226394%26dopt%3DAbstract Conclusions: No previous cases of ranolazine-related DOE requiring drug cessation have been published. Ranolazine may be associated with DOE in this elderly man. PMID: 20226394 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3375003 Mon, 01 Feb 2010 00:00:00 +0100 3375003 http://www.medworm.com/index.php?rid=3375002&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20226395%26dopt%3DAbstract Conclusion: Data from these recently published studies could be used to guide the development and evaluation of quality improvement, research, or clinical practice initiatives. PMID: 20226395 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3375002 Mon, 01 Feb 2010 00:00:00 +0100 3375002 http://www.medworm.com/index.php?rid=3247410&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20129253%26dopt%3DAbstract Conclusions: Evidence indicates that the osteoporosis treatments currently available in the United States are beneficial for treating osteoporosis in geriatric patients. However, data are limited for the oldest patients (>/=80 years) and those with significant comorbidities. Because of the limited availability of data for geriatric patients with significant comorbidities, the properties of the various agents, including efficacy, tolerability, and potential contraindications, should be considered carefully for each geriatric patient. PMID: 20129253 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3247410 Tue, 01 Dec 2009 00:00:00 +0100 3247410 http://www.medworm.com/index.php?rid=3247409&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20129254%26dopt%3DAbstract Conclusions: Overall, there is a scarcity of data regarding the use of pharmacologic agents in older adults with T2DM, and clinical guidance is largely based on data obtained from younger populations. The selection of appropriate drug regimens for these patients remains challenging. PMID: 20129254 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3247409 Tue, 01 Dec 2009 00:00:00 +0100 3247409 http://www.medworm.com/index.php?rid=3247408&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20129255%26dopt%3DAbstract Conclusions: The definitive survival advantage of irinotecan observed in clinical trials was not reproducible in this population of elderly Medicare patients. The results emphasize the need for expansion of trials to include a more diverse patient group as well as continued evaluation of more recent chemotherapies in real-world settings. PMID: 20129255 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3247408 Tue, 01 Dec 2009 00:00:00 +0100 3247408 http://www.medworm.com/index.php?rid=3247407&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20129256%26dopt%3DAbstract Conclusions: The prevalence of transdermal fentanyl use was higher than that of morphine, oxycodone, and hydromorphone among people aged >/=80 years residing in noninstitutional settings in Finland. The variation in use between hospital districts suggests that organizational culture may have a strong impact on prescribing practices. Our data highlight the need for further education regarding the appropriate use of opioids among older people. PMID: 20129256 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3247407 Tue, 01 Dec 2009 00:00:00 +0100 3247407 http://www.medworm.com/index.php?rid=3247406&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20129257%26dopt%3DAbstract Conclusions: This pilot study tested the feasibility of a medication management program designed to improve the quality of medication use in older adults with underlying psychiatric disease. Findings from this study, which will be reported at a later date, will help to refine the program and subsequent testing, with the overall goal of improving the quality of medication use and health outcomes in older adults. PMID: 20129257 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3247406 Tue, 01 Dec 2009 00:00:00 +0100 3247406 http://www.medworm.com/index.php?rid=3247405&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20129258%26dopt%3DAbstract Conclusions: Overall, solifenacin was found to improve symptom bother, HRQoL, work productivity, activity participation, and reduced medical care resource utilization in these elderly subjects with OAB who continued to have urgency symptoms with tolterodine and were willing to try solifenacin. This was an exploratory subgroup analysis of an open-label, noncomparative study; further research is needed to confirm these results. PMID: 20129258 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3247405 Tue, 01 Dec 2009 00:00:00 +0100 3247405 http://www.medworm.com/index.php?rid=3247404&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20129259%26dopt%3DAbstract Conclusion: Based on these findings, a substantial proportion of those Ontarians aged >/=60 years reported NHP use, and there is a need for greater communication with physicians to avoid potential drug-NHP interactions. PMID: 20129259 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3247404 Tue, 01 Dec 2009 00:00:00 +0100 3247404 http://www.medworm.com/index.php?rid=3052921&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19948300%26dopt%3DAbstract Conclusions: HF therapy that has published mortality and morbidity benefits in nonelderly patient populations has been associated with benefits in elderly patients. Elderly patients may have variable pharmacologic responses to these agents and may be susceptible to adverse events and drug-drug interactions due to concurrent treatments for comorbidities. Close monitoring of elderly patients undergoing HF treatment is essential to ensure optimal outcomes. PMID: 19948300 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3052921 Thu, 01 Oct 2009 00:00:00 +0100 3052921 http://www.medworm.com/index.php?rid=3052920&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19948301%26dopt%3DAbstract Conclusions: Antihypertensive medications-particularly ACE inhibitors and diuretics-may be helpful in reducing the risk for and progression of dementia. Large randomized clinical trials are warranted to further explore the relationship between antihypertensive drugs and dementia. PMID: 19948301 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3052920 Thu, 01 Oct 2009 00:00:00 +0100 3052920 http://www.medworm.com/index.php?rid=3052919&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19948302%26dopt%3DAbstract Conclusion: This study found that the utilization of health care resources and economic burden of LTC residents with COPD were primarily due to LTC, pharmacy, and inpatient costs. PMID: 19948302 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3052919 Thu, 01 Oct 2009 00:00:00 +0100 3052919 http://www.medworm.com/index.php?rid=3052918&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19948303%26dopt%3DAbstract Conclusions: Medication underuse was relatively common in this study. Patients with greater comorbidity, but not polypharmacy, had increased odds of undertreatment. PMID: 19948303 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3052918 Thu, 01 Oct 2009 00:00:00 +0100 3052918 http://www.medworm.com/index.php?rid=3052917&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19948304%26dopt%3DAbstract Conclusions: Levetiracetam was a probable cause of depression in these 2 elderly patients. Cautious use and additional monitoring may be necessary when prescribing levetiracetam to elderly patients, especially when prescribing to those with a history of renal impairment. PMID: 19948304 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=3052917 Thu, 01 Oct 2009 00:00:00 +0100 3052917 http://www.medworm.com/index.php?rid=2818181&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19766951%26dopt%3DAbstract Conclusions: In this decision analysis, genotype-guided warfarin therapy for anticoagulation in elderly patients with AF was potentially cost-effective, and its benefits were closely related to efficacy in preventing bleeding events. Clinical trials testing the efficacy of genotype-guided warfarin therapy are warranted. PMID: 19766951 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=2818181 Fri, 31 Jul 2009 23:00:00 +0100 2818181 http://www.medworm.com/index.php?rid=2818180&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19766952%26dopt%3DAbstract Conclusions: Based on the findings of this study, the benefits of treating elderly patients with hypertension in clinical practice may be lower than those reported by HYVET. The study results support the current recommendation that all patients with hypertension should be treated with >1 antihypertensive medication if adequate control is not achieved at low doses of a single medication. PMID: 19766952 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=2818180 Fri, 31 Jul 2009 23:00:00 +0100 2818180 http://www.medworm.com/index.php?rid=2818179&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19766953%26dopt%3DAbstract Conclusions: There was preferential prescribing of SSRI antidepressants among these older aged care home residents with depression. Cognitive impairment alone was not significantly associated with antidepressant prescribing; however, these aged care home residents with dementia and mood disorders had an increased likelihood of being treated with antidepressants. The prescribing of TCAs was significantly associated with concurrent benzodiazepine use. PMID: 19766953 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=2818179 Fri, 31 Jul 2009 23:00:00 +0100 2818179 http://www.medworm.com/index.php?rid=2818178&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19766954%26dopt%3DAbstract Conclusion: This article reports a case of chorea in an elderly patient who was receiving gabapentin for the treatment of anxiety. After gabapentin discontinuation, the chorea resolved completely, indicating a probable adverse drug reaction. PMID: 19766954 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=2818178 Fri, 31 Jul 2009 23:00:00 +0100 2818178 http://www.medworm.com/index.php?rid=2818163&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19766955%26dopt%3DAbstract Authors: Guay DR PMID: 19766955 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=2818163 Fri, 31 Jul 2009 23:00:00 +0100 2818163 http://www.medworm.com/index.php?rid=2622717&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19616182%26dopt%3DAbstract Conclusions: Antipsychotic use increased in US nursing homes from 1996 through 2006 and was associated with certain organizational characteristics and market characteristics. Future interventions to reduce antipsychotic use in nursing homes will have to focus on these factors. PMID: 19616182 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=2622717 Sun, 31 May 2009 23:00:00 +0100 2622717 http://www.medworm.com/index.php?rid=2622716&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19616183%26dopt%3DAbstract Conclusions: We found that polypharmacy was common in older cancer patients and increased during hospitali-zation. We also found that most OACE team recommendations communicated to physicians were implemented even though the primary physicians were not members of the OACE team. Future randomized trials are needed to assess the impact of the OACE team model of care on adverse events, survival, and cost in hospitalized older adult cancer patients. PMID: 19616183 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=2622716 Sun, 31 May 2009 23:00:00 +0100 2622716 http://www.medworm.com/index.php?rid=2622715&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19616184%26dopt%3DAbstract Conclusions: In this well-monitored geriatric population with chronic AF, including patients with falls and/or dementia, a high percentage were prescribed warfarin (85%), with low rates of stroke, hemorrhage, and death at 12 months despite a low TTR. Patients with falls and/or dementia had a high mortality rate (~45%). PMID: 19616184 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=2622715 Sun, 31 May 2009 23:00:00 +0100 2622715 http://www.medworm.com/index.php?rid=2622714&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19616185%26dopt%3DAbstract Conclusions: Despite disappointing results from recently completed Phase III trials of several novel compounds, the extent and breadth of activity at all phases of clinical development suggest that new pharmacotherapeutic options for the treatment of AD will become available within the next decade. PMID: 19616185 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=2622714 Sun, 31 May 2009 23:00:00 +0100 2622714 http://www.medworm.com/index.php?rid=2533374&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19447359%26dopt%3DAbstract CONCLUSION: In this small sample of VA patients with glaucoma, adherence to glaucoma medications could be improved, especially among those who reported difficulties using their medications and those who were nonwhite. PMID: 19447359 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=2533374 Tue, 31 Mar 2009 23:00:00 +0100 2533374 http://www.medworm.com/index.php?rid=2533373&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19447360%26dopt%3DAbstract CONCLUSION: Results of this retrospective analysis suggest that, compared with longer duration of CHEI therapy, discontinuation of CHEIs in these nursing home residents with dementia was associated with some adverse behavioral changes and decreased time spent engaging in leisure-related activities. PMID: 19447360 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=2533373 Tue, 31 Mar 2009 23:00:00 +0100 2533373 http://www.medworm.com/index.php?rid=2533372&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19447361%26dopt%3DAbstract CONCLUSIONS: In this analysis of data from elderly patients at 2 outpatient centers, a small set of 8 medications accounted for the majority of PIMs at both centers, irrespective of geographic and demographic variations. Female sex, polypharmacy, and number of primary care visits were significantly associated with PIM prescribing. In this analysis of data from elderly patients at 2 outpatient centers, a small set of 8 medications accounted for the majority of PIMs at both centers, irrespective of geographic and demographic variations. PMID: 19447361 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=2533372 Tue, 31 Mar 2009 23:00:00 +0100 2533372 http://www.medworm.com/index.php?rid=2533371&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19447362%26dopt%3DAbstract CONCLUSIONS: Geriatricians should assume that the medication lists supplied by GPs are incomplete or incorrect, and be aware that in approximately 25% of patients, symptoms may be caused by medication use inaccurately described in the referral. Reports by the community pharmacy may supply valuable additional information. Because there are also discrepancies between patients and pharmacies, medication use from a database-with data from prescribing physicians and pharmacy systems-will still have to be confirmed by the patient. PMID: 19447362 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=2533371 Tue, 31 Mar 2009 23:00:00 +0100 2533371 http://www.medworm.com/index.php?rid=2533370&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19447363%26dopt%3DAbstract CONCLUSIONS: In this survey, older adults trusted physicians and pharmacists more than the other sources studied to provide information on prescription drugs. Trust in physicians to provide price information was an important moderator of the effect of high drug spending on cost-related nonadhcrence. Efforts to provide patients and their providers with comparative data on drug prices and effectiveness may reduce cost-related nonadhcrence. PMID: 19447363 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=2533370 Tue, 31 Mar 2009 23:00:00 +0100 2533370 http://www.medworm.com/index.php?rid=2533369&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19447364%26dopt%3DAbstract CONCLUSIONS: Viewing of live health insurance presentations and adequate health literacy were associated with greater awareness of important pharmaceutical cost-assistance programs in this study in low-income, elderly individuals. The findings suggest that use of live presentations, in addition to health literacy materials and messages, may be important strategies in promoting knowledge of and enrollment in state and federal pharmaceutical cost-assistance programs for low-income seniors. PMID: 19447364 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=2533369 Tue, 31 Mar 2009 23:00:00 +0100 2533369 http://www.medworm.com/index.php?rid=2263566&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19281935%26dopt%3DAbstract Conclusions: A single dose of IV hydromorphone at 0.0075 mg/kg was neither clinically nor statistically different from IV morphine at 0.05 mg/kg for the treatment of acute, severe pain at 30 minutes postbaseline in these older adults in the ED. The incidence of adverse effects was not statistically different. Our data suggest that hydromorphone and morphine in the doses given had similar efficacy and safety profiles in these older adults. Neither regimen provided >/=50% pain relief for the majority of patients. Future investigations of acute pain management in older adults should examine the efficacy and safety of higher initial (loading) doses of opioids titrated at frequent intervals until adequate analgesia is achieved. PMID: 19281935 [PubMed - in process] (Source: The American J... The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=2263566 Sun, 01 Feb 2009 05:00:00 +0100 2263566 http://www.medworm.com/index.php?rid=2263562&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19281936%26dopt%3DAbstract Conclusions: The DAE RetroDUR was associated with a possible reduction in the use of potentially inappropriate prescription medications in these older adults. Further research, using a control population, is needed to show the impact on health care utilization and costs, adverse drug events, and health care and quality-of-life outcomes. PMID: 19281936 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=2263562 Sun, 01 Feb 2009 05:00:00 +0100 2263562 http://www.medworm.com/index.php?rid=2263558&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19281937%26dopt%3DAbstract Conclusions: The geriatric palliative care team was associated with a reduction in the number of unnecessary medications prescribed for older veterans in this nursing home. Future studies should evaluate the impact of decreasing unnecessary prescribing on clinical outcomes such as adverse drug reactions. PMID: 19281937 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=2263558 Sun, 01 Feb 2009 05:00:00 +0100 2263558 http://www.medworm.com/index.php?rid=2263553&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19281938%26dopt%3DAbstract Conclusions: Various factors make the effect of concomitant administration of meropenem and valproic acid unpredictable, even in the same patient. Caution should be used when administering meropenem and valproic acid concomitantly, especially in elderly patients with central nervous system disorders, even if the patient has had a successful prior experience with these 2 drugs. If concomitant administration is essential, very close serum concentration monitoring and clinical observation are necessary. PMID: 19281938 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=2263553 Sun, 01 Feb 2009 05:00:00 +0100 2263553 http://www.medworm.com/index.php?rid=2263548&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19281939%26dopt%3DAbstract Conclusion: In the absence of definitive evidence of effectiveness, trials of low-dose methylphenidate in medically ill adults with depression, fatigue, or apathy, with monitoring for response and adverse effects, are appropriate. PMID: 19281939 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=2263548 Sun, 01 Feb 2009 05:00:00 +0100 2263548 http://www.medworm.com/index.php?rid=2263543&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19281940%26dopt%3DAbstract Authors: Hanlon JT PMID: 19281940 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=2263543 Sun, 01 Feb 2009 05:00:00 +0100 2263543 http://www.medworm.com/index.php?rid=2263540&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19281941%26dopt%3DAbstract Authors: Guay DR PMID: 19281941 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=2263540 Sun, 01 Feb 2009 05:00:00 +0100 2263540 http://www.medworm.com/index.php?rid=2131202&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19161926%26dopt%3DAbstract Conclusions: Based on the prevalence of medication and nonmedication therapies, levels of osteoporosis care did not differ by ambulatory care setting. However, patterns of care varied by certain visit characteristics, including insurance type, age, and sex. PMID: 19161926 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=2131202 Mon, 01 Dec 2008 05:00:00 +0100 2131202 http://www.medworm.com/index.php?rid=2131201&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19161927%26dopt%3DAbstract Conclusion: Almost 30% of patients receiving a PPI in this academic geriatric practice had no documented indication for PPI use. PMID: 19161927 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=2131201 Mon, 01 Dec 2008 05:00:00 +0100 2131201 http://www.medworm.com/index.php?rid=2131200&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19161928%26dopt%3DAbstract Conclusions: In this sample of older patients assessed for medication management, independent cognitive processes were associated with the ability to set up a medication schedule and overall adherence to prescriptions. Better verbal memory functioning was strongly and independently associated with setting up a medication schedule, while better executive functioning was strongly and independently associated with being fully adherent to prescription instructions. Deficits in either cognitive ability could result in medication errors due to nonadherence. PMID: 19161928 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=2131200 Mon, 01 Dec 2008 05:00:00 +0100 2131200 http://www.medworm.com/index.php?rid=2131199&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19161929%26dopt%3DAbstract Conclusion: Based on this outcome in this patient with UTI, fluoroquinolones should be used with caution, particularly in patients with risk factors predisposing to tendinitis, including advanced age and renal dysfunction. PMID: 19161929 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=2131199 Mon, 01 Dec 2008 05:00:00 +0100 2131199 http://www.medworm.com/index.php?rid=2131198&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19161930%26dopt%3DAbstract Conclusions: In general, unless the patient is engaging in or threatening dangerous acts involving physical contact, serotoninergics (first choice, SSRIs; second choice, TCAs) are first-line agents followed by antiandrogens (cyproterone acetate or medroxyprogesterone acetate) as second-line agents. LHRH agonists (first choice) and estrogens (second choice) are considered third-line agents. Combination therapy is reasonable if the patient fails to respond to monotherapy. PMID: 19161930 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=2131198 Mon, 01 Dec 2008 05:00:00 +0100 2131198 http://www.medworm.com/index.php?rid=2131197&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19161931%26dopt%3DAbstract Authors: Guay DR PMID: 19161931 [PubMed - as supplied by publisher] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=2131197 Mon, 01 Dec 2008 05:00:00 +0100 2131197 http://www.medworm.com/index.php?rid=1990370&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19028374%26dopt%3DAbstract Conclusions: Nearly 1 in 4 elderly nursing home residents in the United States received antipsychotic agents. Predisposing and need factors played a vital role in determining the use of antipsychotic agents in these elderly patients. Overall, the study findings suggest that there is a need to monitor antipsychotic drug use by elderly patients in US nursing homes in light of recent efficacy and safety data on atypical agents. PMID: 19028374 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=1990370 Wed, 01 Oct 2008 04:00:00 +0100 1990370 http://www.medworm.com/index.php?rid=1990369&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19028375%26dopt%3DAbstract Conclusion: In this population of community-dwelling elderly, use of typical agents was associated with an increased risk for hospitalization compared with atypical agents. PMID: 19028375 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=1990369 Wed, 01 Oct 2008 04:00:00 +0100 1990369 http://www.medworm.com/index.php?rid=1990368&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19028376%26dopt%3DAbstract Conclusions: The intervention to improve patient safety by reducing medication delays for patients making the transition from the hospital to the NH was not successfully implemented, as medication orders were not transmitted to the NH-contracted pharmacies before patients' arrival at the NH. All patients making the transition from hospital to NH experienced a >12-hour delay in medication administration, and the mean number of missed doses of medications was >3. There is a need for further exploration of the reasons for and possible solutions to delays in medication administration during the transition to the NH, as well as of the impact of such delays on patient outcomes, including adverse drug events, emergency department visits, and rehospitalizations. PMID: 19028376 [PubMed - ... The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=1990368 Wed, 01 Oct 2008 04:00:00 +0100 1990368 http://www.medworm.com/index.php?rid=1990367&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19028377%26dopt%3DAbstract Conclusions: Among 48,512 medications inspected over 8 weeks in 3 German long-term care facilities, the rate of repackaging errors was 1.3%, involving 7.3% of daily pill organizers and the medications of 53.00% of residents. The largest proportion of errors involved incorrect halving of tablets. PMID: 19028377 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=1990367 Wed, 01 Oct 2008 04:00:00 +0100 1990367 http://www.medworm.com/index.php?rid=1990366&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19028378%26dopt%3DAbstract Conclusion: This longitudinal study is an initial step toward developing more comprehensive, patient-centered measures and interventions to address the quality of medication use in older adults. PMID: 19028378 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=1990366 Wed, 01 Oct 2008 04:00:00 +0100 1990366 http://www.medworm.com/index.php?rid=1779021&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18775387%26dopt%3DAbstract Authors: Donoso VS PMID: 18775387 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=1779021 Mon, 01 Sep 2008 04:00:00 +0100 1779021 http://www.medworm.com/index.php?rid=1779020&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18775388%26dopt%3DAbstract Conclusions: Compared with the IPR cohort, the FSC 500/50 cohort was 45% less likely to have a COPD-related exacerbation event and had similar medical costs. FSC 500/50 was a more effective initial maintenance therapy than IPR for this Medicare population, and, despite the $260 increase in COPD-related pharmacy costs, there was no significant difference in COPD-related medical costs. PMID: 18775388 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=1779020 Mon, 01 Sep 2008 04:00:00 +0100 1779020 http://www.medworm.com/index.php?rid=1779019&cid=s_34436_18_f&fid=34436&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18775389%26dopt%3DAbstract Conclusions: Despite research evidence and recommendations to avoid these CNS-active medications because of their adverse effects, they continue to be prescribed in elderly patients with cognitive impairments. Further research is needed to determine strategies that will help reduce their administration in this population. PMID: 18775389 [PubMed - in process] (Source: The American Journal of Geriatric Pharmacotherapy) The American Journal of Geriatric Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=1779019 Mon, 01 Sep 2008 04:00:00 +0100 1779019