MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'The Annals of Pharmacotherapy' source. Wed, 08 Feb 2012 14:04:31 +0100 http://www.medworm.com/index.php?rid=5625970&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22253190%26dopt%3DAbstract CONCLUSIONS:In this case, no harmful effects on fetal development were observed after exposure to fenofibrate during organogenesis. PMID: 22253190 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5625970 Tue, 17 Jan 2012 05:00:00 +0100 5625970 http://www.medworm.com/index.php?rid=5625969&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22253191%26dopt%3DAbstract CONCLUSIONS:ADR death rates have a clear association with age, race, and urbanization subgroups. Older individuals, males, blacks, and individuals residing in extremely rural areas experienced higher ADR death rates; these findings warrant further study to develop prevention strategies. PMID: 22253191 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5625969 Tue, 17 Jan 2012 05:00:00 +0100 5625969 http://www.medworm.com/index.php?rid=5580033&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22234989%26dopt%3DAbstract CONCLUSIONS:The solid organ transplant population is at an increased risk of severe complications from influenza infection. Identifying risks, preventing illness, and appropriately treating active infection is essential in this patient population. PMID: 22234989 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5580033 Tue, 10 Jan 2012 05:00:00 +0100 5580033 http://www.medworm.com/index.php?rid=5580032&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22234990%26dopt%3DAbstract CONCLUSIONS:Medications should be prescribed carefully for patients at high risk of hypoglycemia, particularly those with diabetes complications or those taking insulin alone or in combination. Additional studies are needed to carefully examine the nature of the association between diabetes-related complications and hypoglycemic episodes. PMID: 22234990 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5580032 Tue, 10 Jan 2012 05:00:00 +0100 5580032 http://www.medworm.com/index.php?rid=5580031&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22234991%26dopt%3DAbstract CONCLUSIONS:DBS may be an option as adjunct therapy in patients whose symptoms are no longer controlled with maximum pharmacologic therapy, but benefits of surgery must be weighed against the risks. PMID: 22234991 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5580031 Tue, 10 Jan 2012 05:00:00 +0100 5580031 http://www.medworm.com/index.php?rid=5566909&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22215685%26dopt%3DAbstract Authors: Wier HA, Kuhn RJ Abstract Aluminum toxicity has been described in patients of all ages who are receiving a variety of therapies, including dialysis, phosphate-binding medications, and parenteral nutrition (PN). Neonates are at an increased risk of aluminum toxicity because of anatomic, physiologic, and nutrition-related factors not present in other populations. In 2004, the Food and Drug Administration recommended restricting daily aluminum administration to 5 μ/kg/day and now requires that additives used to compound PN have the maximum aluminum content at expiration listed on the product label. Although the pharmacist can work to decrease aluminum toxicity in this population, it remains difficult to reach this threshold. PMID: 22215685 [PubMed - as supplied by publis... The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5566909 Tue, 03 Jan 2012 05:00:00 +0100 5566909 http://www.medworm.com/index.php?rid=5566908&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22215686%26dopt%3DAbstract CONCLUSIONS:Belatacept provides a new option for maintenance immunosuppression in adult KTR. Further research is needed to compare its efficacy and safety with standard tacrolimus-based regimens, to evaluate whether increased drug costs are offset by long-term improvements in patient and allograft survival, and to establish its role in the immunosuppression armamentarium. PMID: 22215686 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5566908 Tue, 03 Jan 2012 05:00:00 +0100 5566908 http://www.medworm.com/index.php?rid=5566907&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22215687%26dopt%3DAbstract Authors: Klein-Schwartz W PMID: 22215687 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5566907 Tue, 03 Jan 2012 05:00:00 +0100 5566907 http://www.medworm.com/index.php?rid=5566906&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22215688%26dopt%3DAbstract Authors: Kilickap S, Kesikli SA, Erdis E, Yucel B PMID: 22215688 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5566906 Tue, 03 Jan 2012 05:00:00 +0100 5566906 http://www.medworm.com/index.php?rid=5566905&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22215689%26dopt%3DAbstract CONCLUSIONS:Ranolazine added to optimized doses of CADT demonstrated an improvement in angina symptoms when given to a veteran population with persistent CSA. PMID: 22215689 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5566905 Tue, 03 Jan 2012 05:00:00 +0100 5566905 http://www.medworm.com/index.php?rid=5566904&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22215690%26dopt%3DAbstract Authors: PMID: 22215690 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5566904 Tue, 03 Jan 2012 05:00:00 +0100 5566904 http://www.medworm.com/index.php?rid=5552296&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22202493%26dopt%3DAbstract CONCLUSIONS:All trials reviewed suggest that GLP-1 may be a promising agent for the management of hyperglycemia in critically ill patients, regardless of diabetes status. Additional studies in more heterogeneous intensive care settings comparing GLP-1 with insulin, the current standard of care, are necessary. These studies should evaluate long-term safety and effectiveness of GLP-1 therapy on morbidity and mortality outcomes in critically ill populations. PMID: 22202493 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5552296 Tue, 27 Dec 2011 05:00:00 +0100 5552296 http://www.medworm.com/index.php?rid=5552295&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22202494%26dopt%3DAbstract CONCLUSIONS:Topical application of tranexamic acid and aminocaproic acid to decrease postsurgical bleeding after major surgical procedures is a promising strategy. Further data are needed regarding the safety of this hemostatic approach. PMID: 22202494 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5552295 Tue, 27 Dec 2011 05:00:00 +0100 5552295 http://www.medworm.com/index.php?rid=5552294&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22202495%26dopt%3DAbstract CONCLUSIONS:Warfarin is an effective agent to prevent VTE after elective THA/TKA. The most effective approach, including extended warfarin use up to 4 weeks or longer, has not been determined. PMID: 22202495 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5552294 Tue, 27 Dec 2011 05:00:00 +0100 5552294 http://www.medworm.com/index.php?rid=5552293&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22202496%26dopt%3DAbstract CONCLUSIONS:Establishing protocols for patient-driven management of sedation, analgesia, and delirium is a cost-effective practice and allows savings of nearly $1000 per hospitalization. PMID: 22202496 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5552293 Tue, 27 Dec 2011 05:00:00 +0100 5552293 http://www.medworm.com/index.php?rid=5552292&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22202497%26dopt%3DAbstract CONCLUSIONS:Pharmacist-provider collaboration can result in significant clinical improvements, including A1C reduction and adherence to preventive care measures, when compared to standard care in a medically underserved population with diabetes. PMID: 22202497 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5552292 Tue, 27 Dec 2011 05:00:00 +0100 5552292 http://www.medworm.com/index.php?rid=5552291&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22202498%26dopt%3DAbstract CONCLUSIONS:Further research on the use of dabigatran in patients with recent coronary bypass surgery and heparin/PF4 antibodies is needed before any recommendations can be made. PMID: 22202498 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5552291 Tue, 27 Dec 2011 05:00:00 +0100 5552291 http://www.medworm.com/index.php?rid=5552290&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22202499%26dopt%3DAbstract CONCLUSIONS:This is the first report describing the utility of bortezomib for early graft dysfunction in a highly sensitized lung transplant recipient. Although this patient had preformed donor-specific anti-HLA antibodies, AMR was successfully treated with a combination of plasmapheresis, IVIG, and bortezomib. At time of writing, the patient continued to have excellent graft function 2 years posttransplant. Bortezomib is a potent inhibitor of plasma cell production and it appears to be useful for the treatment of antibody-mediated graft dysfunction. PMID: 22202499 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5552290 Tue, 27 Dec 2011 05:00:00 +0100 5552290 http://www.medworm.com/index.php?rid=5552289&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22202500%26dopt%3DAbstract Authors: Hollands JM PMID: 22202500 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5552289 Tue, 27 Dec 2011 05:00:00 +0100 5552289 http://www.medworm.com/index.php?rid=5537774&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22170974%26dopt%3DAbstract CONCLUSIONS:Sedative and analgesic use may be uniquely higher in critically ill patients with pH1N1 infection compared to patients with other infectious pneumonias. This finding may be important for resource planning in future pandemics. Further study is required to explore the underlying mechanisms for potentially higher sedative and analgesic requirements in this patient population. PMID: 22170974 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5537774 Tue, 20 Dec 2011 05:00:00 +0100 5537774 http://www.medworm.com/index.php?rid=5537771&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22190250%26dopt%3DAbstract CONCLUSIONS:Ketamine for treatment-resistant MDD requires further evaluation before it can be considered a viable treatment option. PMID: 22190250 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5537771 Tue, 20 Dec 2011 05:00:00 +0100 5537771 http://www.medworm.com/index.php?rid=5537770&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22190251%26dopt%3DAbstract CONCLUSIONS:Bariatric surgical procedures may result in altered pharmacokinetic parameters, but the literature is lacking in sufficient quantity and quality of studies to make solid conclusions and recommendations. Until more studies of sufficient power are completed, clinicians should closely monitor these patients in the immediate and distant postsurgical period for signs of both drug efficacy and toxicity and adjust their medications as required. PMID: 22190251 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5537770 Tue, 20 Dec 2011 05:00:00 +0100 5537770 http://www.medworm.com/index.php?rid=5537769&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22190252%26dopt%3DAbstract CONCLUSIONS:Although studies suggest that the echinocandins may have a favorable safety profile, the lack of pharmacokinetic data and standardized study designs limit current recommendations of use of echinocandins as first-line agents in neonates in the treatment of fungal infections. However, if an echinocandin is to be used in this population, the data presented in this review suggest the use of micafungin over the other echinocandins, and higher doses of micafungin (10-15 mg/kg/day) should be used when central nervous system involvement is suspected. PMID: 22190252 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5537769 Tue, 20 Dec 2011 05:00:00 +0100 5537769 http://www.medworm.com/index.php?rid=5537768&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22190253%26dopt%3DAbstract CONCLUSIONS:Patients with a higher initial INR are less likely to achieve adequate INR reversal after receiving 3-factor PCC and may require higher doses than were used in the study. PMID: 22190253 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5537768 Tue, 20 Dec 2011 05:00:00 +0100 5537768 http://www.medworm.com/index.php?rid=5537775&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22170973%26dopt%3DAbstract CONCLUSIONS:Patients receiving incorrectly dosed eptifibatide and bivalirudin are susceptible to adverse bleeding events. The occurrence of incorrect dosing offers an opportunity for pharmacist-driven institutional improvement. PMID: 22170973 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5537775 Tue, 13 Dec 2011 05:00:00 +0100 5537775 http://www.medworm.com/index.php?rid=5537773&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22170975%26dopt%3DAbstract CONCLUSIONS:Based on published data, adverse effect profiles, and cost, clofarabine may be an appropriate alternative to intensive chemotherapy regimens in certain subsets of older patients with newly diagnosed AML. These include patients with a baseline decreased performance status or history of cardiovascular disease who may not tolerate anthracyclines, which are typically a component of most intensive chemotherapy regimens. Additional randomized controlled trials are needed to directly compare the efficacy of clofarabine with that of intensive chemotherapy regimens and to evaluate the potential benefit of combining clofarabine with cytarabine. PMID: 22170975 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5537773 Tue, 13 Dec 2011 05:00:00 +0100 5537773 http://www.medworm.com/index.php?rid=5537772&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22170976%26dopt%3DAbstract CONCLUSIONS:This case demonstrates a serious adverse event potentially associated with vancomycin use, and calls attention to the safety of rechallenging with vancomycin during a possible drug-induced neutropenia. PMID: 22170976 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5537772 Tue, 13 Dec 2011 05:00:00 +0100 5537772 http://www.medworm.com/index.php?rid=5537776&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22147146%26dopt%3DAbstract Authors: Kee VR PMID: 22147146 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5537776 Tue, 06 Dec 2011 05:00:00 +0100 5537776 http://www.medworm.com/index.php?rid=5537790&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22116988%26dopt%3DAbstract CONCLUSIONS: The improved response of this case to tetrabenazine monotherapy suggests that tetrabenazine may be a pharmacologic alternative for patients with poststroke choreoathetosis that is intolerant or unresponsive to antipsychotic agents. Further studies are needed to better define the risk versus benefit profile of tetrabenazine. PMID: 22116988 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5537790 Thu, 01 Dec 2011 05:00:00 +0100 5537790 http://www.medworm.com/index.php?rid=5537789&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22116989%26dopt%3DAbstract CONCLUSIONS: Peramivir is well cleared by CVVH, and drug exposure is potentially predictable based on flow rates. Further study is necessary. PMID: 22116989 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5537789 Thu, 01 Dec 2011 05:00:00 +0100 5537789 http://www.medworm.com/index.php?rid=5537788&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22116990%26dopt%3DAbstract CONCLUSIONS: Based on current studies, sildenafil appears to be well tolerated and can improve markers of cardiovascular and pulmonary function in patients with HF. PDE5 inhibitors may be a therapeutic option for patients who cannot tolerate standard therapy for HF or who remain symptomatic with standard therapy. Larger long-term trials are necessary to better understand the role of PDE5 inhibitors in HF. PMID: 22116990 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5537788 Thu, 01 Dec 2011 05:00:00 +0100 5537788 http://www.medworm.com/index.php?rid=5537787&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22116991%26dopt%3DAbstract Authors: PMID: 22116991 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5537787 Thu, 01 Dec 2011 05:00:00 +0100 5537787 http://www.medworm.com/index.php?rid=5537786&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22116992%26dopt%3DAbstract CONCLUSIONS: In the US, most symptomatic Latrodectus spp. exposures reported to the NPDS are minor. Few patients receive antivenom, although antivenom is associated with shorter symptom duration among moderate and major outcomes. PMID: 22116992 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5537786 Thu, 01 Dec 2011 05:00:00 +0100 5537786 http://www.medworm.com/index.php?rid=5537785&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22116993%26dopt%3DAbstract Authors: Strawn JR, Keeshin BR PMID: 22116993 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5537785 Thu, 01 Dec 2011 05:00:00 +0100 5537785 http://www.medworm.com/index.php?rid=5537784&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22116994%26dopt%3DAbstract CONCLUSIONS: In addition to the well-described serious adverse drug events, including serious infections, the use of etanercept in ankylosing spondylitis can be associated with the development of MGN. Health care providers, especially rheumatologists, should be aware of this potentially serious adverse drug reaction. PMID: 22116994 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5537784 Thu, 01 Dec 2011 05:00:00 +0100 5537784 http://www.medworm.com/index.php?rid=5537783&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22116995%26dopt%3DAbstract CONCLUSIONS: Takotsubo cardiomyopathy is a serious but transient potential complication of electroconvulsive therapy. Limited evidence indicates that β-adrenergic receptor blocking agents may help prevent its reoccurrence in patients needing further electroconvulsive treatment. Health care providers in psychiatry should be aware of this potential complication of electroconvulsive therapy, especially in postmenopausal women. However, many questions remain regarding this issue. PMID: 22116995 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5537783 Thu, 01 Dec 2011 05:00:00 +0100 5537783 http://www.medworm.com/index.php?rid=5537782&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22116996%26dopt%3DAbstract CONCLUSIONS: Azilsartan medoxomil is a safe and effective ARB with a unique pharmacologic profile versus other agents, including slowed angiotensin II type 1 receptor dissociation rates and improved receptor specificity. Studies have shown azilsartan medoxomil 80 mg once daily to reduce BP to a greater extent than valsartan and olmesartan, with similar safety and tolerability. PMID: 22116996 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5537782 Thu, 01 Dec 2011 05:00:00 +0100 5537782 http://www.medworm.com/index.php?rid=5537781&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22116997%26dopt%3DAbstract CONCLUSIONS: Ferumoxytol doses of up to 12 mg elemental iron/kg administered over 15-60 minutes seem to be well tolerated in pediatric patients. Larger prospective studies are needed to determine the incidence and severity of adverse effects associated with ferumoxytol, both during administration and immediately after. Long-term studies will be required to assess to risk for iron overload toxicity. PMID: 22116997 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5537781 Thu, 01 Dec 2011 05:00:00 +0100 5537781 http://www.medworm.com/index.php?rid=5537780&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22128044%26dopt%3DAbstract CONCLUSIONS: PIs do not appear to independently predispose patients to QT interval prolongation. However, other risk factors (both HIV-related and non-HIV-related) may increase the risk of QT interval prolongation. Available data suggest that baseline and follow-up electrocardiogram monitoring are unnecessary precautions, but may be considered in patients who are initiating PI therapy and are on multiple medications with proarrhythmic potential and/or have multiple comorbidities, increasing the risk. PMID: 22128044 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5537780 Thu, 01 Dec 2011 05:00:00 +0100 5537780 http://www.medworm.com/index.php?rid=5537779&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22128045%26dopt%3DAbstract Authors: Li A, Zhao S, Jodlowski TZ PMID: 22128045 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5537779 Thu, 01 Dec 2011 05:00:00 +0100 5537779 http://www.medworm.com/index.php?rid=5537778&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22147144%26dopt%3DAbstract CONCLUSIONS: Ketamine is an effective agent in adults undergoing PSA and RSI in the ED. The best available evidence provides sufficient confidence to consider use of this agent in the ED. PMID: 22147144 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5537778 Thu, 01 Dec 2011 05:00:00 +0100 5537778 http://www.medworm.com/index.php?rid=5537777&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22147145%26dopt%3DAbstract CONCLUSIONS: Potential disparities, particularly among diabetic individuals and those of minority race/ethnicity, were found with regard to BP control and the agents used to treat hypertension. Future studies should address these disparities by designing interventions to improve the treatment of hypertension in high-risk populations. PMID: 22147145 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5537777 Thu, 01 Dec 2011 05:00:00 +0100 5537777 http://www.medworm.com/index.php?rid=5537791&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22116987%26dopt%3DAbstract Authors: Nagaraja HN PMID: 22116987 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5537791 Thu, 24 Nov 2011 05:00:00 +0100 5537791 http://www.medworm.com/index.php?rid=5426985&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22085777%26dopt%3DAbstract CONCLUSIONS:Health care provider callers to the NCCC were highly satisfied with the information obtained from this HIV/AIDS telephone consultation service. By measuring callers' survey response to PharmD and MD consultations, the importance of the clinicians' contributions to this advanced HIV/AIDS consultation service is documented. PMID: 22085777 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5426985 Tue, 15 Nov 2011 05:00:00 +0100 5426985 http://www.medworm.com/index.php?rid=5426984&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22085778%26dopt%3DAbstract CONCLUSIONS:While available literature establishes the efficacy of 8 drugs in treatment of PHN, it does not provide adequate guidance as to which agents are best to treat this condition, in part because of inadequate reporting of data on tolerability and safety. PMID: 22085778 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5426984 Tue, 15 Nov 2011 05:00:00 +0100 5426984 http://www.medworm.com/index.php?rid=5426988&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22068241%26dopt%3DAbstract Comment: Use of Recalibrated Serum Creatinine Concentrations for Adjustment of Drug Dosages: Determination of Values Compatible with Conventional Dosing Recommendations (December). Ann Pharmacother. 2011 Nov 8; Authors: Palacio-Lacambra ME, Jiménez-Lozano I, Vidal-Otero J, Montoro-Ronsano JB PMID: 22068241 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5426988 Tue, 08 Nov 2011 05:00:00 +0100 5426988 http://www.medworm.com/index.php?rid=5426987&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22068242%26dopt%3DAbstract CONCLUSIONS:Pharmacists play an important role in a short-term medical mission trip by serving as sources for medication knowledge and ensuring appropriate medication therapy management as part of the interdisciplinary team. PMID: 22068242 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5426987 Tue, 08 Nov 2011 05:00:00 +0100 5426987 http://www.medworm.com/index.php?rid=5426986&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22068243%26dopt%3DAbstract Authors: Youngblood FE, Knaak E, Rose J, Malesker MA PMID: 22068243 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5426986 Tue, 08 Nov 2011 05:00:00 +0100 5426986 http://www.medworm.com/index.php?rid=5382845&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22028416%26dopt%3DAbstract CONCLUSIONS: The use of rFVIIa for rapid decrease of INR in a patient with FHF prior to an invasive procedure was safe and efficacious. When considering the use of rFVIIa, clinicians should be aware of the risk of thrombosis. In our experience, and in the limited literature on the matter, rFVIIa 40 μg/kg appears to be an appropriate dose for decrease of the INR. Further studies are needed to confirm this finding. PMID: 22028416 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5382845 Tue, 01 Nov 2011 04:00:00 +0100 5382845 http://www.medworm.com/index.php?rid=5382844&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22028417%26dopt%3DAbstract CONCLUSIONS: There is inconsistency between retrospective and prospective studies of generic AED substitution. The highest levels of evidence indicate that there should not be a problem with generic substitution, although some patients are more prone to problems with the generic products. Some evidence suggests that switches between multiple generic AED products in certain individuals may be problematic. PMID: 22028417 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5382844 Tue, 01 Nov 2011 04:00:00 +0100 5382844 http://www.medworm.com/index.php?rid=5382843&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22028418%26dopt%3DAbstract CONCLUSIONS: Pharmacist-led group SMA visits are efficacious in attainment of glycemic control in patients with diabetes and depression without change in depression symptoms. PMID: 22028418 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5382843 Tue, 01 Nov 2011 04:00:00 +0100 5382843 http://www.medworm.com/index.php?rid=5382841&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22028420%26dopt%3DAbstract CONCLUSIONS: Pictograms improve the recall of targeted medication information among patients receiving antiretroviral therapy for HIV management; however, this appears to be dependent on the fact that these patients received a verbal explanation of each pictogram prior to use. PMID: 22028420 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5382841 Tue, 01 Nov 2011 04:00:00 +0100 5382841 http://www.medworm.com/index.php?rid=5382839&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22028422%26dopt%3DAbstract CONCLUSIONS: Vemurafenib offers a novel, first-line, personalized therapy for patients who have mutated BRAF. Clinical trials of vemurafenib in combination with ipilimumab or other targeted or cytotoxic chemotherapeutic agents may provide more effective regimens with long-term clinical benefit. PMID: 22028422 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5382839 Tue, 01 Nov 2011 04:00:00 +0100 5382839 http://www.medworm.com/index.php?rid=5382837&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22028424%26dopt%3DAbstract CONCLUSIONS: Results from clinical trials and current safety data suggest that rosiglitazone should not be used for the treatment of AD. Application of results from trials evaluating pioglitazone in the treatment of AD is limited because of major trial limitations; therefore, it should not be recommended at this time. Although these drugs are not commonly used in the treatment of AD, further pharmacoepidemiologic studies are warranted before their use can be recommended. PMID: 22028424 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5382837 Tue, 01 Nov 2011 04:00:00 +0100 5382837 http://www.medworm.com/index.php?rid=5382827&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22028425%26dopt%3DAbstract Authors: PMID: 22028425 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5382827 Tue, 01 Nov 2011 04:00:00 +0100 5382827 http://www.medworm.com/index.php?rid=5382826&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22045904%26dopt%3DAbstract CONCLUSIONS:Based on published immunogenicity and safety data, as well as the recent recommendations by the ACIP for routine use in infants and indications for high-risk pediatric patients, PCV13 is a revised formulation of pneumococcal vaccine that should be included on pharmacy formularies. PMID: 22045904 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5382826 Tue, 01 Nov 2011 04:00:00 +0100 5382826 http://www.medworm.com/index.php?rid=5382819&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22045905%26dopt%3DAbstract CONCLUSIONS:Data from small pilot studies suggest that ferumoxytol may improve image quality in MRA; however, further investigation is necessary to establish its efficacy and safety. Large randomized, active-comparator trials are needed to establish optimal dosing, imaging procedures, and safety monitoring. PMID: 22045905 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5382819 Tue, 01 Nov 2011 04:00:00 +0100 5382819 http://www.medworm.com/index.php?rid=5382814&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22045906%26dopt%3DAbstract Authors: Nawarskas JJ PMID: 22045906 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5382814 Tue, 01 Nov 2011 04:00:00 +0100 5382814 http://www.medworm.com/index.php?rid=5382809&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22045907%26dopt%3DAbstract Authors: Nau DP Abstract The federal government is increasing its push for a high-value health care system by increasing transparency and accountability related to quality. The Medicare program has begun to publicly rate the quality of Medicare plans, includingprescription drug plans, and is transforming its payment policies to reward plans that deliver the highest levels of quality. These policies will have a cascade effect on pharmacies and pharmacists as the Medicare plans look for assistance in improving the quality of medication use. This commentary describes the Medicare policies directed toward improvement of quality and their effect on pharmacy payment and opportunities for pharmacists to affirm their role in a high-quality medication use system. PMID: 22045907 [PubMed ... The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5382809 Tue, 01 Nov 2011 04:00:00 +0100 5382809 http://www.medworm.com/index.php?rid=5382797&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22045908%26dopt%3DAbstract CONCLUSIONS:Linaclotide appears to be a safe and effective treatment for IBS. Additional clinical trials will more fully elucidate the safety profile of linaclotide and better define its place in therapy. PMID: 22045908 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5382797 Tue, 01 Nov 2011 04:00:00 +0100 5382797 http://www.medworm.com/index.php?rid=5382842&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22028419%26dopt%3DAbstract Authors: Kroon L PMID: 22028419 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5382842 Tue, 25 Oct 2011 04:00:00 +0100 5382842 http://www.medworm.com/index.php?rid=5382840&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22028421%26dopt%3DAbstract Authors: Werner KE PMID: 22028421 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5382840 Tue, 25 Oct 2011 04:00:00 +0100 5382840 http://www.medworm.com/index.php?rid=5382838&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22028423%26dopt%3DAbstract Authors: Wisniewski AM PMID: 22028423 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5382838 Tue, 25 Oct 2011 04:00:00 +0100 5382838 http://www.medworm.com/index.php?rid=5347080&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22009992%26dopt%3DAbstract CONCLUSIONS:Retrospective and prospective data demonstrate that rFVIIa effectively reverses elevated PT and INR, reducing the risk of bleeding and safely facilitating invasive procedures. Based on available data, a dose of 20-40 μg/kg 30 minutes prior to an invasive procedure should be considered in patients with acute or chronic liver failure at risk for bleeding complications. A major limitation of rFVIIa use is the high cost of therapy. A prospective, randomized trial could help determine the appropriate dose of rFVIIa, timing of dose in relationship to procedure, and usefulness of subsequent doses. PMID: 22009992 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5347080 Tue, 18 Oct 2011 04:00:00 +0100 5347080 http://www.medworm.com/index.php?rid=5347079&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22009993%26dopt%3DAbstract CONCLUSIONS:These considerations should be part of the formulary review process; however, when considering the significant role MRSA plays in ABSSSI in both the community and hospital settings, we believe that ceftaroline will provide clinicians with a welcome option in addition to currently available anti-MRSA therapies for the treatment of ABSSSI. PMID: 22009993 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5347079 Tue, 18 Oct 2011 04:00:00 +0100 5347079 http://www.medworm.com/index.php?rid=5347078&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22009994%26dopt%3DAbstract Authors: Iskandar JW, Wood RL, Ali R, Alemu F PMID: 22009994 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5347078 Tue, 18 Oct 2011 04:00:00 +0100 5347078 http://www.medworm.com/index.php?rid=5347077&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22009995%26dopt%3DAbstract Authors: Beckett RD, Heck Sheehan A Abstract OBJECTIVE:To determine whether clinical trial data support the use of nitroglycerin for prevention of postmenopausal osteoporosis.DATA SOURCES:A literature search using MEDLINE (1966-September 2011) and EMBASE (1973-September 2011) was conducted using the search terms nitroglycerin, bone mineral density, fracture, and osteoporosis. References of identified articles were reviewed for additional citations.STUDY SELECTION AND DATA EXTRACTION:All English-language articles related to the use of nitroglycerin ointment in postmenopausal women were reviewed.DATA SYNTHESIS:Four observational studies reported significant improvements in bone mineral density of postmenopausal women with the use of nitrates. One pilot study and 2 prospective, random... The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5347077 Tue, 18 Oct 2011 04:00:00 +0100 5347077 http://www.medworm.com/index.php?rid=5347076&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22009996%26dopt%3DAbstract Authors: Heil EL, Daniels LM, Walko CM, Nicolau DP PMID: 22009996 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5347076 Tue, 18 Oct 2011 04:00:00 +0100 5347076 http://www.medworm.com/index.php?rid=5347075&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22009997%26dopt%3DAbstract CONCLUSIONS:An intravenous infusion including a dextrose:insulin ratio of 3.3:1, compared with a higher ratio, results in less hyperglycemia and appears to be as effective in decreasing potassium concentrations in newborns. PMID: 22009997 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5347075 Tue, 18 Oct 2011 04:00:00 +0100 5347075 http://www.medworm.com/index.php?rid=5347074&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22009998%26dopt%3DAbstract CONCLUSIONS:Weight-based dosing with enoxaparin in morbidly obese SICU patients was effective in achieving anti-factor Xa levels within the appropriate prophylactic range. This regimen reduced the rate of VTE below expected levels and no additional adverse effects were reported. PMID: 22009998 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5347074 Tue, 18 Oct 2011 04:00:00 +0100 5347074 http://www.medworm.com/index.php?rid=5347073&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22009999%26dopt%3DAbstract CONCLUSIONS:Providers should consider cardiac monitoring during carboplatin infusion in patients with known cardiac disease or at high risk of cardiac complications. PMID: 22009999 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5347073 Tue, 18 Oct 2011 04:00:00 +0100 5347073 http://www.medworm.com/index.php?rid=5347072&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22010000%26dopt%3DAbstract Authors: Moffett BS PMID: 22010000 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5347072 Tue, 18 Oct 2011 04:00:00 +0100 5347072 http://www.medworm.com/index.php?rid=5347071&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22010001%26dopt%3DAbstract CONCLUSIONS:While lacosamide has been reported as an effective treatment for refractory status epilepticus, there is insufficient evidence for its routine use. For cases in which the risks associated with anesthetizing drugs are believed to outweigh the benefits, such as in complex partial status epilepticus, lacosamide may be a reasonable option after more established drug therapies fail. PMID: 22010001 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5347071 Tue, 18 Oct 2011 04:00:00 +0100 5347071 http://www.medworm.com/index.php?rid=5347070&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22010002%26dopt%3DAbstract Authors: Formea CM PMID: 22010002 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5347070 Tue, 18 Oct 2011 04:00:00 +0100 5347070 http://www.medworm.com/index.php?rid=5347069&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22010003%26dopt%3DAbstract CONCLUSIONS:Outcomes among dialysis-dependent patients who received aminoglycosides were below expectations. Various risk factors for mortality were identified, including retention of the catheter, inadequate empiric therapy, and a Cp:MIC <6 mg/L. Improved approaches to dosing of aminoglycosides in dialysis-dependent patients, including more aggressive dosing practices, should beurgently explored in attempts to maximize favorable patient outcomes. PMID: 22010003 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5347069 Tue, 18 Oct 2011 04:00:00 +0100 5347069 http://www.medworm.com/index.php?rid=5347068&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22010004%26dopt%3DAbstract DISCUSSION:Common drug interaction resources do not consistently list an interaction between warfarin and extended-release niacin. The mechanism of niacin-induced coagulopathy is theorized to be related to diminished coagulation factors, and limited data suggest that this may be more pronounced with extended-release niacin. Because of the described effects of niacin on the coagulationcascade and the possibility for pharmacokinetic interactions, there is a potential for synergistic coagulopathy when combined with warfarin therapy. For patients taking both medications, more frequent INR monitoring than that which drug interaction references suggest may be advised. An OBJECTIVE: An interaction between niacin and warfarin likely elevated the INR in this patient because of synergistic coagulopa... The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5347068 Tue, 18 Oct 2011 04:00:00 +0100 5347068 http://www.medworm.com/index.php?rid=5347082&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21990937%26dopt%3DAbstract CONCLUSIONS:Although it cannot be stated definitively, available evidence suggests that moxifloxacin appears to be as effective as ethambutol and is possibly as effective as isoniazid in the treatment of pulmonary TB. Given the generally poor second-line options for the treatment of TB, moxifloxacin is an attractive option as an alternative drug in TB treatment. PMID: 21990937 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5347082 Tue, 11 Oct 2011 04:00:00 +0100 5347082 http://www.medworm.com/index.php?rid=5347081&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21990938%26dopt%3DAbstract CONCLUSIONS:The OPAT team optimized safety, efficacy, and convenience of OPAT while providing substantial cost savings. Further studies are needed to confirm the program's cost-effectiveness. PMID: 21990938 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5347081 Tue, 11 Oct 2011 04:00:00 +0100 5347081 http://www.medworm.com/index.php?rid=5301750&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21972251%26dopt%3DAbstract CONCLUSIONS:Beers criteria utility extended beyond direct measurement of a limited set of inappropriate prescribing practices by serving as a clinically meaningful proxy for other inappropriate practices. Using prescribing quality indicators to guide interventions should thus identify patients for comprehensive medication review, rather than identifying specific medication targets for discontinuation. Future research should explore both the quality measurement and the intervention targeting applications of the Beers criteria, particularly when integrated with other indicators. PMID: 21972251 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5301750 Tue, 04 Oct 2011 04:00:00 +0100 5301750 http://www.medworm.com/index.php?rid=5301749&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21972252%26dopt%3DAbstract CONCLUSIONS:NMS should be considered as a rare complication of therapy with antipsychotics and agents that alter dopamine activity, especially in patients with a history of the syndrome. Careful consideration should be given regarding the risks and benefits of using non-antipsychotic dopamine antagonists in patients with a history of antipsychotic-induced NMS. PMID: 21972252 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5301749 Tue, 04 Oct 2011 04:00:00 +0100 5301749 http://www.medworm.com/index.php?rid=5301773&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21881031%26dopt%3DAbstract CONCLUSIONS: Cisplatin might affect the anticoagulation function of warfarin. Careful INR monitoring is necessary during antineoplastic chemotherapy with cisplatin in patients taking warfarin. PMID: 21881031 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5301773 Sat, 01 Oct 2011 04:00:00 +0100 5301773 http://www.medworm.com/index.php?rid=5301772&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21881032%26dopt%3DAbstract CONCLUSIONS: Patients with renal dysfunction require a reduced dose of bivalirudin to reach a therapeutic aPTT goal. Slightly higher doses may be observed in patients receiving hemodialysis. PMID: 21881032 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5301772 Sat, 01 Oct 2011 04:00:00 +0100 5301772 http://www.medworm.com/index.php?rid=5301771&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21881033%26dopt%3DAbstract Authors: Panas M, Karadima G, Kalfakis N, Vassilopoulos D PMID: 21881033 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5301771 Sat, 01 Oct 2011 04:00:00 +0100 5301771 http://www.medworm.com/index.php?rid=5301770&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21881034%26dopt%3DAbstract CONCLUSIONS: Upon initiation of dabigatran therapy, surveillance for hyper-sensitivity reactions should be included as part of routine drug monitoring. PMID: 21881034 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5301770 Sat, 01 Oct 2011 04:00:00 +0100 5301770 http://www.medworm.com/index.php?rid=5301769&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21896919%26dopt%3DAbstract CONCLUSIONS: The main finding of this study was the association between heavy drinking and subsequent initiation of sedative/anxiolytic drugs that was not fully explained by baseline depressive symptoms. This may inform strategies to optimize the use of sedative/anxiolytic drugs, and assist in the early identification of patients at risk of heavy drinking. Clinicians should consider a patient's alcohol consumption prior to prescribing or dispensing sedative/anxiolytic drugs. Clinicians should also monitor patients prescribed sedative/anxiolytic drugs for subsequent heavy drinking. PMID: 21896919 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5301769 Sat, 01 Oct 2011 04:00:00 +0100 5301769 http://www.medworm.com/index.php?rid=5301768&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21896920%26dopt%3DAbstract CONCLUSIONS: The MM-USCPACK program is a useful and reliable tool for prediction of serum vancomycin concentrations in patients hospitalized in ICU and likely reflects the close monitoring of renal function in this setting. For some patients (more severely ill, obese, or significant change in renal function during vancomycin therapy), predictions were less precise. PMID: 21896920 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5301768 Sat, 01 Oct 2011 04:00:00 +0100 5301768 http://www.medworm.com/index.php?rid=5301767&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21896923%26dopt%3DAbstract CONCLUSIONS: Prasugrel may be considered a therapeutic alternative in some patients allergic or intolerant to clopidogrel, but additional data are warranted to make a strong conclusion. PMID: 21896923 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5301767 Sat, 01 Oct 2011 04:00:00 +0100 5301767 http://www.medworm.com/index.php?rid=5301766&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21896924%26dopt%3DAbstract CONCLUSIONS: Clinical evidence suggests that ofatumumab is an effective agent in patients with CLL refractory to fludarabine and alemtuzumab. Data are awaited comparing ofatumumab to other salvage regimens. Until results of head-to-head trials are conducted comparing ofatumumab to existing regimens, it cannot be said whether ofatumumab is more efficacious or tolerable than currently available therapies. PMID: 21896924 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5301766 Sat, 01 Oct 2011 04:00:00 +0100 5301766 http://www.medworm.com/index.php?rid=5301765&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21917553%26dopt%3DAbstract Authors: Jennings DL, Brewer R, Smith C, Williams C PMID: 21917553 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5301765 Sat, 01 Oct 2011 04:00:00 +0100 5301765 http://www.medworm.com/index.php?rid=5301764&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21917554%26dopt%3DAbstract CONCLUSIONS: Estradiol valerate/dienogest is an effective oral contraceptive. Because it has more stringent start times and requires a longer duration of backup contraception and stricter adherence, estradiol valerate/dienogest should be reserved for patients who are intolerant of other combination oral contraceptives. PMID: 21917554 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5301764 Sat, 01 Oct 2011 04:00:00 +0100 5301764 http://www.medworm.com/index.php?rid=5301763&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21917555%26dopt%3DAbstract CONCLUSIONS: Health care providers and patients should be educated on the advantages and risks associated with vitamin D supplementation and be informed of safety measures to avoid hypervitaminosis D. In addition, health care providers should understand dosage conversion regarding vitamin D and electronic prescribing and dispensing software should be designed to detect such errors. PMID: 21917555 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5301763 Sat, 01 Oct 2011 04:00:00 +0100 5301763 http://www.medworm.com/index.php?rid=5301762&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21917556%26dopt%3DAbstract Authors: Flaherty DK Abstract In 1998, Dr. Andrew Wakefield, a British gastroenterologist, described a new autism phenotype called the regressive autism-enterocolitis syndrome triggered by environmental factors such as measles, mumps, and rubella (MMR) vaccination. The speculative vaccination-autism connection decreased parental confidence in public health vaccination programs and created a public health crisis in England and questions about vaccine safety in North America. After 10 years of controversy and investigation, Dr. Wakefield was found guilty of ethical, medical, and scientific misconduct in the publication of the autism paper. Additional studies showed that the data presented were fraudulent. The alleged autism-vaccine connection is, perhaps, the most damaging medical ho... The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5301762 Sat, 01 Oct 2011 04:00:00 +0100 5301762 http://www.medworm.com/index.php?rid=5301761&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21917557%26dopt%3DAbstract CONCLUSIONS: The incidence of hospitalized rhabdomyolysis is rare, but higher in patients with concomitant statin-fibrate treatment than in patients on statin therapy alone. The rate found in this study is consistent with the known profile of the statin-fibrate treatment option for mixed dyslipidemia. PMID: 21917557 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5301761 Sat, 01 Oct 2011 04:00:00 +0100 5301761 http://www.medworm.com/index.php?rid=5301760&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21917558%26dopt%3DAbstract CONCLUSIONS: Clinicians should be aware that an additional adverse effect of lithium may be an exacerbation of stutter. PMID: 21917558 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5301760 Sat, 01 Oct 2011 04:00:00 +0100 5301760 http://www.medworm.com/index.php?rid=5301759&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21934032%26dopt%3DAbstract Authors: Michalets EL, Pounders CL, Hollis SJ, Sutherland S PMID: 21934032 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5301759 Sat, 01 Oct 2011 04:00:00 +0100 5301759 http://www.medworm.com/index.php?rid=5301758&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21934033%26dopt%3DAbstract Authors: Croes S, Neef C, Stolk LM PMID: 21934033 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5301758 Sat, 01 Oct 2011 04:00:00 +0100 5301758 http://www.medworm.com/index.php?rid=5301757&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21934034%26dopt%3DAbstract CONCLUSIONS: Most febrile episodes in patients with gram-negative severe sepsis or septic shock were not treated with antipyretic medications. Further studies are needed to demonstrate the effect of antipyretics on clinically relevant outcomes in severe sepsis and septic shock. PMID: 21934034 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5301757 Sat, 01 Oct 2011 04:00:00 +0100 5301757 http://www.medworm.com/index.php?rid=5301756&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21934035%26dopt%3DAbstract CONCLUSIONS: Yawning is rarely a serious adverse reaction and is not frequently listed in the drug summary. Most available data are based on case reports, small studies, and older literature. Clinicians should be aware of the agents commonly triggering this behavior. PMID: 21934035 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5301756 Sat, 01 Oct 2011 04:00:00 +0100 5301756 http://www.medworm.com/index.php?rid=5301755&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21934036%26dopt%3DAbstract CONCLUSIONS: Current practices and perceptions surrounding recognition and treatment of delirium in patients in the ICU by the critical care pharmacists surveyed are heterogeneous. Antipsychotics are frequently recommended by pharmacists for delirium treatment, despite a lack of rigorous evidence to support their use. While pharmacists are ideally suited to lead delirium recognition efforts and provide treatment recommendations in this area, these roles need further elucidation. The optimal pedagogical strategy to support these efforts remains unclear, and the potential impact of pharmacists' efforts on patients' outcomes is unknown. PMID: 21934036 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5301755 Sat, 01 Oct 2011 04:00:00 +0100 5301755 http://www.medworm.com/index.php?rid=5301754&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21954446%26dopt%3DAbstract CONCLUSIONS: Supportive therapies, including angiotensin blockade, should be considered as first-line therapy for patients with urine protein >0.5 g/day and/or blood pressure >140/90 mm Hg. Corticosteroids could be considered as add-on or monotherapy for patients with urine protein >1 g/day with preserved renal function. Conclusive data are lacking for general treatment recommendations for the use of other therapies for IgAN. PMID: 21954446 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5301754 Sat, 01 Oct 2011 04:00:00 +0100 5301754 http://www.medworm.com/index.php?rid=5301753&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21954448%26dopt%3DAbstract CONCLUSIONS: Patients with osteoporosis who are treated with intravenous bisphosphonates do not appear to have a statistically significant increase in the incidence of osteonecrosis of the jaw over 3 years compared with those who do not receive such treatment. Future studies will further contribute to our understanding of the bisphosphonate risk profile, thereby allowing patients and physicians to more rigorously assess the risk-benefit ratio of this treatment across different clinical scenarios. PMID: 21954448 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5301753 Sat, 01 Oct 2011 04:00:00 +0100 5301753 http://www.medworm.com/index.php?rid=5301752&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21954449%26dopt%3DAbstract CONCLUSIONS: Sunitinib may induce hyperammonemic encephalopathy in some patients. Although further studies are warranted, clinicians should be aware of this severe adverse event when using sunitinib for treatment of GIST. PMID: 21954449 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5301752 Sat, 01 Oct 2011 04:00:00 +0100 5301752 http://www.medworm.com/index.php?rid=5301751&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21954450%26dopt%3DAbstract CONCLUSIONS: A Phase 3 trial in patients with AF revealed apixaban to be superior to warfarin for stroke and systemic embolism prophylaxis, with lower rates of major bleeding. Further studies will help to confirm the role of apixaban for other indications. PMID: 21954450 [PubMed - in process] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5301751 Sat, 01 Oct 2011 04:00:00 +0100 5301751 http://www.medworm.com/index.php?rid=5266893&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21954445%26dopt%3DAbstract Authors: Harper ML PMID: 21954445 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5266893 Tue, 27 Sep 2011 04:00:00 +0100 5266893 http://www.medworm.com/index.php?rid=5266892&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21954446%26dopt%3DAbstract CONCLUSIONS:Supportive therapies, including angiotensin blockade, should be considered as first-line therapy for patients with urine protein >0.5 g/day and/or blood pressure >140/90 mm Hg. Corticosteroids could be considered as add-on or monotherapy for patients with urine protein >1 g/day with preserved renal function. Conclusive data are lacking for general treatment recommendations for the use of other therapies for IgAN. PMID: 21954446 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5266892 Tue, 27 Sep 2011 04:00:00 +0100 5266892 http://www.medworm.com/index.php?rid=5266891&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21954447%26dopt%3DAbstract CONCLUSIONS:Clinical trials have failed to demonstrate a consistent beneficial effect of probiotics in mechanically ventilated patients; thus, they are not recommended for routine clinical use. However, heterogeneity among study designs may hinder this assessment and the designs should be unified in future research. PMID: 21954447 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5266891 Tue, 27 Sep 2011 04:00:00 +0100 5266891 http://www.medworm.com/index.php?rid=5266890&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21954448%26dopt%3DAbstract CONCLUSIONS:Patients with osteoporosis who are treated with intravenous bisphosphonates do not appear to have a statistically significant increase in the incidence of osteonecrosis of the jaw over 3 years compared with those who do not receive such treatment. Future studies will further contribute to our understanding of the bisphosphonate risk profile, thereby allowing patients and physicians to more rigorously assess the risk-benefit ratio of this treatment across different clinical scenarios. PMID: 21954448 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5266890 Tue, 27 Sep 2011 04:00:00 +0100 5266890 http://www.medworm.com/index.php?rid=5266888&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21954449%26dopt%3DAbstract CONCLUSIONS:Sunitinib may induce hyperammonemic encephalopathy in some patients. Although further studies are warranted, clinicians should be aware of this severe adverse event when using sunitinib for treatment of GIST. PMID: 21954449 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5266888 Tue, 27 Sep 2011 04:00:00 +0100 5266888 http://www.medworm.com/index.php?rid=5266887&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21954450%26dopt%3DAbstract CONCLUSIONS:A Phase 3 trial in patients with AF revealed apixaban to be superior to warfarin for stroke and systemic embolism prophylaxis,with lower rates of major bleeding. Further studies will help to confirm the role of apixaban for other indications. PMID: 21954450 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5266887 Tue, 27 Sep 2011 04:00:00 +0100 5266887 http://www.medworm.com/index.php?rid=5266898&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21934032%26dopt%3DAbstract AUTHORS' REPLY. Ann Pharmacother. 2011 Sep 20; Authors: Landrum Michalets E, Pounders CL, Hollis SJ, Sutherland S PMID: 21934032 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5266898 Tue, 20 Sep 2011 04:00:00 +0100 5266898 http://www.medworm.com/index.php?rid=5266897&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21934033%26dopt%3DAbstract Authors: Croes S, Neef C, Stolk LM PMID: 21934033 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5266897 Tue, 20 Sep 2011 04:00:00 +0100 5266897 http://www.medworm.com/index.php?rid=5266896&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21934034%26dopt%3DAbstract CONCLUSIONS:Most febrile episodes in patients with gram-negative severe sepsis or septic shock were not treated with antipyretic medications. Further studies are needed to demonstrate the effect of antipyretics on clinically relevant outcomes in severe sepsis and septic shock. PMID: 21934034 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5266896 Tue, 20 Sep 2011 04:00:00 +0100 5266896 http://www.medworm.com/index.php?rid=5266895&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21934035%26dopt%3DAbstract CONCLUSIONS:Yawning is rarely a serious adverse reaction and is not frequently listed in the drug summary. Most available data are based on case reports, small studies, and older literature. Clinicians should be aware of the agents commonly triggering this behavior. PMID: 21934035 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5266895 Tue, 20 Sep 2011 04:00:00 +0100 5266895 http://www.medworm.com/index.php?rid=5266894&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21934036%26dopt%3DAbstract CONCLUSIONS:Current practices and perceptions surrounding recognition and treatment of delirium in patients in the ICU by the critical care pharmacists surveyed are heterogeneous. Antipsychotics are frequently recommended by pharmacists for delirium treatment, despite a lack of rigorous evidence to support their use. While pharmacists are ideally suited to lead delirium recognition efforts and provide treatment recommendations in this area, these roles need further elucidation. The optimal pedagogical strategy to support these efforts remains unclear, and the potential impact of pharmacists' efforts on patients' outcomes isunknown. PMID: 21934036 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5266894 Tue, 20 Sep 2011 04:00:00 +0100 5266894 http://www.medworm.com/index.php?rid=5234708&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21917553%26dopt%3DAbstract Authors: Jennings DL, Brewer R, Smith C PMID: 21917553 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5234708 Tue, 13 Sep 2011 04:00:00 +0100 5234708 http://www.medworm.com/index.php?rid=5234707&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21917554%26dopt%3DAbstract CONCLUSIONS:Estradiol valerate/dienogest is an effective oral contraceptive. Because it has more stringent start times and requires a longer duration of back-up contraception and stricter adherence, estradiol valerate/dienogest should be reserved for patients who are intolerant of other combination oral contraceptives. PMID: 21917554 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5234707 Tue, 13 Sep 2011 04:00:00 +0100 5234707 http://www.medworm.com/index.php?rid=5234706&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21917555%26dopt%3DAbstract CONCLUSIONS:Health care providers and patients should be educated on the advantages and risks associated with vitamin D supplementation and be informed of safety measures to avoid hypervitaminosis D. In addition, health care providers should understand dosage conversion regarding vitamin D and electronic prescribing and dispensing software should be designed to detect such errors. PMID: 21917555 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5234706 Tue, 13 Sep 2011 04:00:00 +0100 5234706 http://www.medworm.com/index.php?rid=5234705&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21917556%26dopt%3DAbstract Authors: Flaherty DK Abstract In 1998, Dr. Andrew Wakefield, a British gastroenterologist, described a new autism phenotype called the regressive autism-enterocolitis syndrome triggered by environmental factors such as measles, mumps, and rubella (MMR) vaccination. The speculative vaccination-autism connection decreased parental confidence in public health vaccination programs and created a public health crisis in England and questions about vaccine safety in North America. After 10 years of controversy and investigation, Dr. Wakefield was found guilty of ethical, medical, and scientific misconduct in the publication of the autism paper. Additional studies showed that the data presented were fraudulent. The alleged autism-vaccine connection is, perhaps, the most damaging medical ho... The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5234705 Tue, 13 Sep 2011 04:00:00 +0100 5234705 http://www.medworm.com/index.php?rid=5234704&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21917557%26dopt%3DAbstract CONCLUSIONS:The incidence of hospitalized rhabdomyolysis is rare, but higher in patients with concomitant statin-fibrate treatment than in patients on statin therapy alone. The rate found in this study is consistent with the known profile of the statin-fibrate treatment option for mixed dyslipidemia. PMID: 21917557 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5234704 Tue, 13 Sep 2011 04:00:00 +0100 5234704 http://www.medworm.com/index.php?rid=5234703&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21917558%26dopt%3DAbstract CONCLUSIONS:Clinicians should be aware that an additional adverse effect of lithium may be an exacerbation of stutter. PMID: 21917558 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5234703 Tue, 13 Sep 2011 04:00:00 +0100 5234703 http://www.medworm.com/index.php?rid=5221261&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21896919%26dopt%3DAbstract CONCLUSIONS:The main finding of this study was the association between heavy drinking and subsequent initiation of sedative/anxiolytic drugs that was not fully explained by baseline depressive symptoms. This may inform strategies to optimize the use of sedative/anxiolytic drugs, and assist in the early identification of patients at risk of heavy drinking. Clinicians should consider a patient's alcohol consumption prior to prescribing or dispensing sedative/anxiolytic drugs. Clinicians should also monitor patients prescribed sedative/anxiolytic drugs for subsequent heavy drinking. PMID: 21896919 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5221261 Tue, 06 Sep 2011 04:00:00 +0100 5221261 http://www.medworm.com/index.php?rid=5221260&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21896920%26dopt%3DAbstract CONCLUSIONS:The MM-USCPACK program is a useful and reliable tool for prediction of serum vancomycin concentrations in patients hospitalized in ICU and likely reflects the close monitoring of renal function in this setting. For some patients (more severely ill, obese, or significant change in renal function during vancomycin therapy), predictions were less precise. PMID: 21896920 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5221260 Tue, 06 Sep 2011 04:00:00 +0100 5221260 http://www.medworm.com/index.php?rid=5221259&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21896921%26dopt%3DAbstract Authors: Blair MM PMID: 21896921 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5221259 Tue, 06 Sep 2011 04:00:00 +0100 5221259 http://www.medworm.com/index.php?rid=5221258&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21896922%26dopt%3DAbstract Authors: Bhatt-Mehta V PMID: 21896922 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5221258 Tue, 06 Sep 2011 04:00:00 +0100 5221258 http://www.medworm.com/index.php?rid=5221257&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21896923%26dopt%3DAbstract CONCLUSIONS:Prasugrel may be considered a therapeutic alternative in some patients allergic or intolerant to clopidogrel, but additional data are warranted to make a strong conclusion. PMID: 21896923 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5221257 Tue, 06 Sep 2011 04:00:00 +0100 5221257 http://www.medworm.com/index.php?rid=5221256&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21896924%26dopt%3DAbstract CONCLUSIONS:Clinical evidence suggests that ofatumumab is an effective agent in patients with CLL refractory to fludarabine and alemtuzumab. Data are awaited comparing ofatumumab to other salvage regimens. Until results of head-to-head trials are conducted comparing ofatumumab to existing regimens, it cannot be said whether ofatumumab is more efficacious or tolerable than currently available therapies. PMID: 21896924 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5221256 Tue, 06 Sep 2011 04:00:00 +0100 5221256 http://www.medworm.com/index.php?rid=5221255&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21896925%26dopt%3DAbstract Authors: Martin SJ PMID: 21896925 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5221255 Tue, 06 Sep 2011 04:00:00 +0100 5221255 http://www.medworm.com/index.php?rid=5221254&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21896926%26dopt%3DAbstract Authors: Schommer JC PMID: 21896926 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5221254 Tue, 06 Sep 2011 04:00:00 +0100 5221254 http://www.medworm.com/index.php?rid=5221264&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21881032%26dopt%3DAbstract CONCLUSIONSPatients with renal dysfunction require a reduced dose of bivalirudin to reach a therapeutic aPTT goal. Slightly higher doses may be observed in patients receiving hemodialysis. PMID: 21881032 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5221264 Thu, 01 Sep 2011 04:00:00 +0100 5221264 http://www.medworm.com/index.php?rid=5221265&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21881031%26dopt%3DAbstract CONCLUSIONS:Cisplatin might affect the anticoagulation function of warfarin. Careful INR monitoring is necessary during antineoplastic chemotherapy with cisplatin in patients taking warfarin. PMID: 21881031 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5221265 Wed, 31 Aug 2011 04:00:00 +0100 5221265 http://www.medworm.com/index.php?rid=5221263&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21881033%26dopt%3DAbstract Authors: Panas M, Karadima G, Kalfakis N, Vassilopoulos D PMID: 21881033 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5221263 Wed, 31 Aug 2011 04:00:00 +0100 5221263 http://www.medworm.com/index.php?rid=5221262&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21881034%26dopt%3DAbstract CONCLUSIONS:Upon initiation of dabigatran therapy, surveillance for hypersensitivity reactions should be included as part of routine drug monitoring. PMID: 21881034 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5221262 Wed, 31 Aug 2011 04:00:00 +0100 5221262 http://www.medworm.com/index.php?rid=5180161&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21878658%26dopt%3DAbstract CONCLUSIONS:The documentation system allowed for the determination of the frequency and types of DRPs, as well as the recommendations made to resolve them in community pharmacy practice. Use of the software, including its electronic prompts, significantly increased the documentation of interventions by pharmacists. PMID: 21878658 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5180161 Mon, 29 Aug 2011 23:00:00 +0100 5180161 http://www.medworm.com/index.php?rid=5180160&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21878659%26dopt%3DAbstract CONCLUSIONS:Budesonide may be an additional treatment option for patients with AIH but without cirrhosis who are intolerant to standard therapy with prednisone or prednisone with azathioprine. PMID: 21878659 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5180160 Mon, 29 Aug 2011 23:00:00 +0100 5180160 http://www.medworm.com/index.php?rid=5180159&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21878660%26dopt%3DAbstract CONCLUSIONS:We propose that laboratory findings that include dopamine and serotonin metabolites can be used as adjuncts to clinical and prescription histories in the diagnosis of NMS. The use of urinary catecholamine as a diagnostic aid in NMS needs further evaluation. PMID: 21878660 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5180159 Mon, 29 Aug 2011 23:00:00 +0100 5180159 http://www.medworm.com/index.php?rid=5160181&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21862711%26dopt%3DAbstract CONCLUSIONS: In the setting of DHCA, bivalirudin should be used cautiously, with frequent monitoring of the ACTs and potential cessation of the infusion in anticipation of prolonged drug effect with subsequent potential coagulopathy. If coagulopathy ensues, use of low-dose rFVIIa may be an option to initiate hemostasis. When using rFVIIa, it is important to consider the risk of thrombosisand monitor patients accordingly. PMID: 21862711 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5160181 Mon, 22 Aug 2011 23:00:00 +0100 5160181 http://www.medworm.com/index.php?rid=5160180&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21862712%26dopt%3DAbstract Authors: Goutelle S, Neely M, Bleyzac N PMID: 21862712 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5160180 Mon, 22 Aug 2011 23:00:00 +0100 5160180 http://www.medworm.com/index.php?rid=5160179&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21862713%26dopt%3DAbstract CONCLUSIONS: Montelukast may be an effective treatment option in the management of interstitial cystitis. Further research is needed to substantiate this novel use. PMID: 21862713 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5160179 Mon, 22 Aug 2011 23:00:00 +0100 5160179 http://www.medworm.com/index.php?rid=5160178&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21862714%26dopt%3DAbstract CONCLUSIONS: Use of oral, single-agent, broad-spectrum fluoroquinolones for outpatient treatment of FN in low-risk patients has shown promising results. At this time, this type of therapy should be limited to low-risk patients. Future clinical trials should include larger sample sizes and a comparison with existing first-line oral therapy-oral ciprofloxacin plus amoxicillin/clavulanate. PMID: 21862714 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5160178 Mon, 22 Aug 2011 23:00:00 +0100 5160178 http://www.medworm.com/index.php?rid=5160177&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21862715%26dopt%3DAbstract Authors: Gómez-Ulloa D, Bundó AV, Mateu-de Antonio J, Arriola E PMID: 21862715 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5160177 Mon, 22 Aug 2011 23:00:00 +0100 5160177 http://www.medworm.com/index.php?rid=5160176&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21862716%26dopt%3DAbstract Authors: Smith MA Abstract Innovation in health care is difficult yet necessary in this era of health care delivery and payment reform. The Center for Medicare and Medicaid Services (CMS) Innovation Center and the CMS Partnership for Patients have announced priority areas to achieve better health, better care, and reduced costs through continuous improvement. Pharmacists possess the therapeutic knowledge and medication process expertise to create collaborative and innovative solutions that address medication use and safety problems. As a profession, we face a call to action. As pharmacy practitioners, educators, and researchers, we face an unprecedented opportunity to make a difference. So, either individually or collectively in our workplaces and pharmacist professional organizati... The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5160176 Mon, 22 Aug 2011 23:00:00 +0100 5160176 http://www.medworm.com/index.php?rid=5160175&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21862717%26dopt%3DAbstract CONCLUSIONS Continued efforts are needed to prevent DVT/PE after abdominal and orthopedic surgery. Initiatives that encourage outpatient prophylaxis must ensure that appropriate prophylaxis of adequate duration is prescribed to all atrisk surgical patients to further reduce DVT/PE across the continuum of care. Pharmacists can play an important role in optimizing continuity of patient care in the prevention of DVT, in providing anticoagulation services that can help reduce the incidence of DVT/PE and bleeding complications, and in helping hospitals achieve performance measures. PMID: 21862717 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5160175 Mon, 22 Aug 2011 23:00:00 +0100 5160175 http://www.medworm.com/index.php?rid=5160195&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21852587%26dopt%3DAbstract Authors: Hayes GL, Mazur JE PMID: 21852587 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5160195 Wed, 17 Aug 2011 23:00:00 +0100 5160195 http://www.medworm.com/index.php?rid=5160194&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21852588%26dopt%3DAbstract CONCLUSIONS: To our knowledge, this is the first report of immediate-release oxybutynin successfully reducing clozapine-induced sialorrhea. If oxybutynin is considered for this indication, use of the immediate-release formulation seems prudent. Additional data, including randomized controlled trials, are needed to confirm whether immediate-release oxybutynin has a significant role in the management of this stigmatizing adverse effect. PMID: 21852588 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5160194 Wed, 17 Aug 2011 23:00:00 +0100 5160194 http://www.medworm.com/index.php?rid=5160193&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21852589%26dopt%3DAbstract Authors: Schullo-Feulner AM PMID: 21852589 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5160193 Wed, 17 Aug 2011 23:00:00 +0100 5160193 http://www.medworm.com/index.php?rid=5160192&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21852590%26dopt%3DAbstract Authors: Chavez ML PMID: 21852590 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5160192 Wed, 17 Aug 2011 23:00:00 +0100 5160192 http://www.medworm.com/index.php?rid=5160191&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21852591%26dopt%3DAbstract CONCLUSIONS: Chronic use of domperidone may, on rare occasions, induce neuropsychiatric syndromes similar to those seen with the use of antipsychotics. This may be more likely in situations in which the blood-brain barrier is damaged, as in vascular and degenerative dementias. PMID: 21852591 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5160191 Wed, 17 Aug 2011 23:00:00 +0100 5160191 http://www.medworm.com/index.php?rid=5160190&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21852592%26dopt%3DAbstract CONCLUSIONS Lubiprostone may be an effective option for the treatment of constipation in adults with CF. PMID: 21852592 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5160190 Wed, 17 Aug 2011 23:00:00 +0100 5160190 http://www.medworm.com/index.php?rid=5160189&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21852593%26dopt%3DAbstract CONCLUSIONS Baseline assessment of cardiovascular medication monitoring is variable. Quality measurement of adherence to BBW recommendations may improve monitoring. PMID: 21852593 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5160189 Wed, 17 Aug 2011 23:00:00 +0100 5160189 http://www.medworm.com/index.php?rid=5160188&cid=s_37308_13_f&fid=37308&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21852594%26dopt%3DAbstract Authors: Buring SM, Winkle JL PMID: 21852594 [PubMed - as supplied by publisher] (Source: The Annals of Pharmacotherapy) The Annals of Pharmacotherapy journals http://www.medworm.com/rss/comments.php?id=5160188 Wed, 17 Aug 2011 23:00:00 +0100 5160188