MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'The Australasian Journal of Dermatology' source. Thu, 18 Mar 2010 14:07:46 +0100 http://www.medworm.com/index.php?rid=3270247&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20148830%26dopt%3DAbstract Authors: Peñas PF, Zaman S Allogeneic haematopoietic stem cell transplantation is increasingly used in the treatment of malignant and non-malignant disorders. Despite ongoing advances in the field, morbidity and mortality related to graft-versus-host disease remains a major barrier to its application. Graft-versus-host disease is a difficult-to-diagnose disease. Dermatologists are involved due to its diverse cutaneous expression. In order to appropriately diagnose, classify and treat this complex disease, knowledge of its expanding cutaneous expression is required. This review provides a synopsis of the clinical manifestations of acute, lichenoid and sclerodermatous phases of graft-versus-host disease with a look at the current evidence surrounding its differential diagnosis. ... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3270247 Mon, 01 Feb 2010 00:00:00 +0100 3270247 http://www.medworm.com/index.php?rid=3270246&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20148831%26dopt%3DAbstract Authors: PMID: 20148831 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3270246 Mon, 01 Feb 2010 00:00:00 +0100 3270246 http://www.medworm.com/index.php?rid=3270245&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20148832%26dopt%3DAbstract Authors: PMID: 20148832 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3270245 Mon, 01 Feb 2010 00:00:00 +0100 3270245 http://www.medworm.com/index.php?rid=3270244&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20148833%26dopt%3DAbstract Authors: Ling A, Dawkins R, Bailey M, Leung M, Cleland H, Serpell J, Kelly J Guidelines for the surgical treatment of cutaneous primary malignant melanoma are well established; however, the approach to the treatment of the regional lymph nodes remains more controversial. In many centres, sentinel lymph node biopsy has been adopted as routine in the treatment of malignant melanoma for prognostic purposes, as it is not of proven therapeutic benefit. The Multicentre Selective Lymphadenectomy Trial II aims to determine the comparative benefits of subsequent completion lymphadenectomy versus observation in those found to have a positive sentinel node biopsy. Until results are available, the risks of the procedure must be weighed against the value of prognostic information gained from perfor... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3270244 Mon, 01 Feb 2010 00:00:00 +0100 3270244 http://www.medworm.com/index.php?rid=3270243&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20148834%26dopt%3DAbstract Authors: Zagarella SS PMID: 20148834 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3270243 Mon, 01 Feb 2010 00:00:00 +0100 3270243 http://www.medworm.com/index.php?rid=3270242&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20148835%26dopt%3DAbstract Authors: Yoong C, Vun YY, Spelman L, Muir J A tattoo reaction which appeared solely on the blue pigment of a 6-month old red and blue football club tattoo of an ardent fan was investigated. The patient was otherwise asymptomatic and no other abnormality was detected on full physical examination. Histology revealed a florid sarcoidal granuloma reaction to blue pigment. Preliminary investigations for systemic sarcoidosis did not reveal any abnormality. The tattoo reaction flattened clinically with the institution of a short course of topical mometasone furoate 0.1% ointment and as the subject remained asymptomatic, close surveillance for the development of systemic sarcoidosis is to continue. The possibility of delayed type hypersensitivity is discussed. PMID: 20148835 [PubMed - in p... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3270242 Mon, 01 Feb 2010 00:00:00 +0100 3270242 http://www.medworm.com/index.php?rid=3270241&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20148836%26dopt%3DAbstract Authors: Roberts H, Tate B A 39-year-old man presented with a 6-month history of a treatment-resistant facial dermatitis. The patient regularly used his mobile phone, predominantly on the left cheek. Patch testing confirmed the clinical suspicion of mobile phone contact dermatitis from nickel contained in the phone casing. Although infrequently reported, with the trend towards metallic mobile phone casings and the high incidence of nickel sensitization in the community, the incidence of mobile phone contact dermatitis is likely to increase. PMID: 20148836 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3270241 Mon, 01 Feb 2010 00:00:00 +0100 3270241 http://www.medworm.com/index.php?rid=3270240&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20148837%26dopt%3DAbstract Authors: Upjohn E, Braue A, Ryan A A 73-year-old man presented a 9-month history of an enlarging nodule on his right temple. Dermoscopy revealed a non-pigmented lesion with ulceration, fibrosis and pale globules. An excisional biopsy was carried out and histology showed a biphasic tumour with a basal cell carcinoma like epithelial component and a dermal undifferentiated sarcoma, with pleomorphic spindle cells and numerous osteoclast-like giant cells. Based on immunohistochemistry findings, a diagnosis of primary cutaneous carcinosarcoma was made and the patient underwent wide local excision. PMID: 20148837 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3270240 Mon, 01 Feb 2010 00:00:00 +0100 3270240 http://www.medworm.com/index.php?rid=3270239&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20148838%26dopt%3DAbstract We report a case of a 48-year-old Chinese female patient with a long-standing history of poorly controlled generalized pustular psoriasis which was resistant to multiple therapies. During a severe flare, a single dose of infliximab resulted in rapid clearing of cutaneous lesions, together with resolution of liver function abnormalities that are likely secondary to neutrophilic cholangitis. Subsequent maintenance therapy with acitretin allowed remission of pustular disease for 7 months. This demonstrates the efficacy of single-dose infliximab for both cutaneous lesions and systemic hepatic involvement in generalized pustular psoriasis. PMID: 20148838 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3270239 Mon, 01 Feb 2010 00:00:00 +0100 3270239 http://www.medworm.com/index.php?rid=3270238&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20148839%26dopt%3DAbstract We report a patient with Darier's disease successfully treated with photodynamic therapy. She had previously been recalcitrant to treatment with emollients, topical corticosteroids and retinoids. Photodynamic therapy was trialled with significant clinical improvement in her cutaneous symptoms and signs that was maintained for over 27 months. PMID: 20148839 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3270238 Mon, 01 Feb 2010 00:00:00 +0100 3270238 http://www.medworm.com/index.php?rid=3270237&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20148840%26dopt%3DAbstract Authors: Mirceva V, Hein R, Ring J, Möhrenschlager M Fabry disease is a rare, X-chromosome-linked lysosomal storage disease caused by a deficient alpha-galactosidase A enzyme. The disease manifests primarily in affected hemizygous males and to some extent in heterozygous females ('carrier'). A 45-year-old female Fabry disease patient without angiokeratomas but with numerous angiomas is presented. Her leukocyte alpha-galactosidase A activity was reduced (0.35 nmol/min/mg protein; normal range: 0.4-1). The analysis of her alpha-galactosidase A gene (exon 1-7) showed the transition c.427 G>A. An intrafamilial follow-up search detected a reduced leukocyte alpha-galactosidase A activity in her father, who suffered exclusively from coronary heart disease. Our case report underlines t... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3270237 Mon, 01 Feb 2010 00:00:00 +0100 3270237 http://www.medworm.com/index.php?rid=3270236&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20148841%26dopt%3DAbstract We report a case of simultaneous brain tuberculomas and scrofuloderma occurring in the same patient. Skin biopsies confirmed scrofuloderma and the patient was successfully treated for tuberculosis with resolution of the brain masses. This case illustrates the importance of dermatological manifestations of systemic disease as an accessible source for diagnosis and guidance in appropriate therapy. PMID: 20148841 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3270236 Mon, 01 Feb 2010 00:00:00 +0100 3270236 http://www.medworm.com/index.php?rid=3270235&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20148842%26dopt%3DAbstract We report a 15-year-old boy who presented with a crusted and papillomatous plaque over the right scapular region. Histopathological examination of this plaque revealed pseudostratified ciliated columnar epithelium with papillary invaginations that included mucinous material. The lesion had no cyst or sinus formation and was bordered with smooth muscle bundles in stroma. PMID: 20148842 [PubMed - as supplied by publisher] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3270235 Mon, 01 Feb 2010 00:00:00 +0100 3270235 http://www.medworm.com/index.php?rid=3270234&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20148843%26dopt%3DAbstract We describe a 24-year-old woman who presented with a 3-month history of multiple tender, occasionally discharging cystic nodules involving the left side of her face in a sporotrichoid distribution. She had suffered a cat scratch to her left lower eyelid 3 weeks before the onset of the eruption and owned multiple tropical fish tanks. She was systemically well and had no lymphadenopathy. She had a background history of a 4.5-mm-thick nodular melanoma of her temple treated by wide local excision and negative sentinel lymph node biopsy 4 years prior. Skin biopsies showed multiple variably sized granulomas surrounded by thick cuffs of lymphocytes involving the superficial and deep dermis with no organisms seen on Ziehl-Neelsen, peroidic acid-Schiff and methenamine silver stains. Laboratory inve... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3270234 Mon, 01 Feb 2010 00:00:00 +0100 3270234 http://www.medworm.com/index.php?rid=3270233&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20148844%26dopt%3DAbstract Authors: Borchard K, Puy R, Nixon R Hyaluronidase is a bovine or ovine testicular protein that is used as an adjunct to co-administered medicaments and fluids to enhance their dispersion and absorption through the degradation of hyaluronan. While it is a known potential allergen, there are few reports of hyaluronidase hypersensitivity. A 56-year-old lady presented 8 hours post glaucoma surgery with ipsilateral lacriminorrhoea, periorbital erythema, oedema, proptosis, pruritis and conjunctival chemosis. Right ocular motility was restricted and visual acuity was reduced. The reaction settled with oral corticosteroids and antihistamines. Hyaluronidase allergy was confirmed on skin prick testing. Hyaluronidase allergy is rare. In the few cases reported, reactions occurred at various doses ... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3270233 Mon, 01 Feb 2010 00:00:00 +0100 3270233 http://www.medworm.com/index.php?rid=3270232&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20148845%26dopt%3DAbstract Authors: Verma GK, Sharma NL, Shanker V, Mahajan VK, Kaushik R, Verma S, Jindal N Amoebiasis cutis is a rare manifestation of Entamoeba histolytica, primarily an intestinal pathogen, which occurs as a complication of amoebic dysentery. Primary cutaneous amoebiasis occurs from contamination of pre-existing wounds. A high degree of clinical suspicion and demonstration of trophozoites from lesions are important for making an early diagnosis lest these patients should suffer significant morbidity. A HIV-negative and otherwise healthy 40-year-old man presented with a well-defined, indurated, painful, progressively enlarging plaque with overlying ulcers and pus discharging sinuses involving buttocks, perianal/perineal area and part of the left thigh of 3 years' duration. A wide array of inve... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3270232 Mon, 01 Feb 2010 00:00:00 +0100 3270232 http://www.medworm.com/index.php?rid=3270231&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20148846%26dopt%3DAbstract Authors: Ricciardo B, Kumar S, O'Callaghan J, Boyce Z This case study is presented to exemplify the application of peripheral nerve field stimulation in the treatment of recalcitrant notalgia paraesthetica. The patient was a 60-year-old woman with severe and disabling notalgia paraesthetica. The itch persisted despite the use of several medications - topical and oral. Following a successful trial of peripheral nerve field stimulation with a temporary electrode, two subcutaneous electrodes were inserted into the affected area with a battery implanted subcutaneously in her right buttock. The patient was reviewed at 5 months post implantation. She reported a greater than 85% improvement in her itch. She also reported a major improvement in her quality of life, with particular improvement ... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3270231 Mon, 01 Feb 2010 00:00:00 +0100 3270231 http://www.medworm.com/index.php?rid=3270230&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20148847%26dopt%3DAbstract Authors: Preda V, Henderson C, Woods J A 41-year-old Phillipino man presented with a 3-year history of a relapsing and remitting generalized chronic pruritic erythematous papular and plaque-like eruption. Investigations showed a persistently elevated eosinophil count. His disease was limited to cutaneous involvement with an absence of demonstrable internal organ involvement, despite extensive investigations and multidisciplinary review. Other causes of eosinophilia were excluded. A diagnosis of idiopathic hypereosinophilic syndrome was made. Our patient's presentation raises a number of issues related to hypereosinophilic syndrome. In particular, relating to managing hypereosinophilic syndrome and the challenge of minimizing therapy side-effects. Our case highlights the considerable mo... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3270230 Mon, 01 Feb 2010 00:00:00 +0100 3270230 http://www.medworm.com/index.php?rid=3270229&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20148848%26dopt%3DAbstract We report a 24-year-old man who presented with the sudden onset of unilateral poliosis associated with acute trigeminal autonomic cephalalgia, suggesting a pathophysiology in common and a possible neural hypothesis in the development of segmental vitiligo. Although rare, associations with neurological abnormalities should be considered in cases of focal depigmentation disorders. PMID: 20148848 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3270229 Mon, 01 Feb 2010 00:00:00 +0100 3270229 http://www.medworm.com/index.php?rid=3270228&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20148849%26dopt%3DAbstract Authors: Watson A PMID: 20148849 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3270228 Mon, 01 Feb 2010 00:00:00 +0100 3270228 http://www.medworm.com/index.php?rid=3270227&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20148850%26dopt%3DAbstract Authors: De Giorgi V, Rossari S, Grazzini M, Fondi C, Massi D, Lotti T PMID: 20148850 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3270227 Mon, 01 Feb 2010 00:00:00 +0100 3270227 http://www.medworm.com/index.php?rid=3270226&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20148851%26dopt%3DAbstract Authors: Lim AC Hyaluronic acid gel is a commonly used skin/soft tissue filler in cosmetic dermatology. Hyaluronic acid fillers are packaged in proprietary luer-lock syringes that can be injected via a 30-gauge, 27-gauge or larger diameter needle depending on the consistency of the gel. A method of decanting proprietary hyaluronic acid fillers into multiple 31-gauge insulin syringes for injection is described. The use of a 31-gauge insulin syringe for filler injections can potentially enhance the injection process through more accurate product delivery and placement. This has the potential to produce a more balanced and symmetrical outcome for patients. Additional benefits include less injection pain, less bleeding/bruising and higher levels of patient satisfaction. PMID: 20148851 ... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3270226 Mon, 01 Feb 2010 00:00:00 +0100 3270226 http://www.medworm.com/index.php?rid=3270225&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20148852%26dopt%3DAbstract Authors: Lim AC There is an ever-expanding range of hyaluronic acid fillers with varying physical characteristics available to cosmetic dermatologists. These fillers are commercially packaged in syringes of approximately 1 mL (range 0.5-2 mL) volume. Filler injectors are currently qualitatively and quantitatively restricted to fillers packaged in ready-to-go syringes. Patients often present for pan-facial rejuvenation requiring varying amounts of fillers as well as more than one type/subtype of filler for optimum correction. The potpourri approach allows access to a range of prepared hyaluronic acid filler subtypes that can be used on the same patient in the one session. The potpourri method centres on the use of multiple 31-gauge insulin syringes prepared with a range of different hya... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3270225 Mon, 01 Feb 2010 00:00:00 +0100 3270225 http://www.medworm.com/index.php?rid=3270224&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20148853%26dopt%3DAbstract Authors: Magee J PMID: 20148853 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3270224 Mon, 01 Feb 2010 00:00:00 +0100 3270224 http://www.medworm.com/index.php?rid=3270223&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20148854%26dopt%3DAbstract Authors: Weston S PMID: 20148854 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3270223 Mon, 01 Feb 2010 00:00:00 +0100 3270223 http://www.medworm.com/index.php?rid=3270222&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20148855%26dopt%3DAbstract Authors: Saunders H PMID: 20148855 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3270222 Mon, 01 Feb 2010 00:00:00 +0100 3270222 http://www.medworm.com/index.php?rid=3270221&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20148856%26dopt%3DAbstract Authors: Tran D PMID: 20148856 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3270221 Mon, 01 Feb 2010 00:00:00 +0100 3270221 http://www.medworm.com/index.php?rid=3004588&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19916964%26dopt%3DAbstract Authors: Kovalyshyn I, Braun R, Marghoob A Congenital melanocytic naevi, consisting of clusters of naevo-melanocytes, develop in utero. Although many congenital naevi are visible at birth, some may not become evident until later in life. The timing of naevo-melanocyte proliferation, senescence and melanogenesis may all contribute towards determining when a naevus will become clinically manifest on the skin. Besides the fact that congenital melanocytic naevi may be aesthetically displeasing, resulting in a multitude of psychosocial issues, they also increase the risk for developing cutaneous melanoma, leptomeningeal melanoma, neurocutaneous melanocytosis, malformations of the brain and, rarely, other tumours such as rhabdomyosarcoma and liposarcoma. Whereas the risk of developing malign... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3004588 Sun, 01 Nov 2009 00:00:00 +0100 3004588 http://www.medworm.com/index.php?rid=3004587&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19916966%26dopt%3DAbstract Authors: Smith SD, Fischer G Lichen sclerosus (LS) in children is uncommon; however, it is an important differential diagnosis in any pre-pubertal child presenting with chronic vulval symptoms. The long-term prognosis is unknown; however, recent data suggests that the assumption that the condition will resolve at puberty may be incorrect. Children with LS require long-term management with topical corticosteroids, which remains the treatment of choice, as well as long-term follow up. We review the current literature on paediatric vulval LS. PMID: 19916966 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3004587 Sun, 01 Nov 2009 00:00:00 +0100 3004587 http://www.medworm.com/index.php?rid=3004586&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19916967%26dopt%3DAbstract We report the results of eight patients with inoperable MCC treated with RTx alone between 1993 and 2007 at Westmead Hospital, Sydney, Australia, and also review the relevant literature on definitive RTx in the treatment of MCC. The median age at diagnosis was 82.5 years in five women and three men. All patients were Caucasian and none were immunosuppressed. Seven of eight patients were clinically node-positive. The mean duration of follow up was 12 months. A median dose of 50 Gy was prescribed. Seven of eight patients with inoperable MCC achieved in-field control, with most eventually relapsing distantly. Treatment-related toxicity was acceptable. In keeping with our results, other studies also report high rates of in-field locoregional control following RTx alone. These findings highligh... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3004586 Sun, 01 Nov 2009 00:00:00 +0100 3004586 http://www.medworm.com/index.php?rid=3004585&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19916968%26dopt%3DAbstract Authors: Cherian P, Tait CP Malignant melanoma is a major contributor to Australian morbidity and mortality. In this era of resource rationalisation, we seek to address the issue of whether routine full-skin examination by a dermatologist, rather than focussed examination of flagged lesions, will increase melanoma diagnosis. A retrospective chart review was undertaken between 1 July 2007 and 30 June 2008 in a private dermatology group practice in order to ascertain the number and characteristics of incidentally detected melanomas on routine skin examination. A total of 94 melanomas were detected during this 12-month period. Of these, 57 (60.6%) were incidentally detected by the dermatologist, 41 (71.9%) were in situ melanomas and 16 (28.1%) were invasive melanoma. Of the invasive lesio... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3004585 Sun, 01 Nov 2009 00:00:00 +0100 3004585 http://www.medworm.com/index.php?rid=3004584&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19916969%26dopt%3DAbstract Authors: Yoong C, De'Ambrosis B Currently, the National Health and Medical Research Council do not have any recommendations about the frequency of follow up after treatment of primary cutaneous invasive squamous cell cancer (SCC), due to a lack of data. The present study aimed to establish appropriate follow-up times and to determine the long-term risk of subsequent non-melanoma skin cancers and melanoma. Patients who had a primary invasive cutaneous SCC excised during 1996 were retrospectively identified from the databases of a dermatologist in private practice in south-east Queensland. Data on size, site, depth, differentiation, perineural involvement, lymphovascular involvement of the index SCC were obtained. The patients were regularly followed up and lymph-node involvement, patien... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3004584 Sun, 01 Nov 2009 00:00:00 +0100 3004584 http://www.medworm.com/index.php?rid=3004583&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19916970%26dopt%3DAbstract Authors: Damian DL, Shannon KF, Saw RP, Thompson JF Topical immunotherapy with contact sensitizers for metastatic melanoma was first reported more than 30 years ago. Diphencyprone (DPCP) immunotherapy is frequently used to treat cutaneous warts and alopecia areata, and we have previously reported the use of DPCP as a single agent to successfully treat extensive, radiotherapy-resistant melanoma metastases on the scalp. We now report DPCP treatment of a further six patients with cutaneous metastatic melanoma. Of seven patients treated with DPCP thus far, four have demonstrated complete responses of their cutaneous lesions and three have had partial responses. The treatment was well-tolerated by all patients. Topical immunotherapy with DPCP is inexpensive and relatively non-invasive and s... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3004583 Sun, 01 Nov 2009 00:00:00 +0100 3004583 http://www.medworm.com/index.php?rid=3004582&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19916971%26dopt%3DAbstract We report three cases of paediatric ocular rosacea responding to prolonged treatment with oral erythromycin. Our cases demonstrate the close association of periorificial dermatitis with childhood rosacea, and highlight the importance of eye signs in its diagnostic criteria. PMID: 19916971 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3004582 Sun, 01 Nov 2009 00:00:00 +0100 3004582 http://www.medworm.com/index.php?rid=3004581&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19916972%26dopt%3DAbstract We present two female children aged 7 years with extensive multifocal venous malformations complicated by chronic localized intravascular coagulation. In both cases ultrasonography and magnetic resonance imaging revealed extensive venous malformations involving the skin, mucous membranes and pharynx, which were not apparent on clinical examination. Haematological investigations demonstrated persistent elevation of the D-dimer, consistent with chronic localized intravascular coagulation. The course of one patient was complicated by the development of multiple painful thromboses at distant sites following percutaneous sclerotherapy. Persistent elevation of the D-dimer occurring in association with large venous and veno-lymphatic malformations has been termed chronic localized intravascular c... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3004581 Sun, 01 Nov 2009 00:00:00 +0100 3004581 http://www.medworm.com/index.php?rid=3004580&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19916973%26dopt%3DAbstract We report a case of type I cryoglobulinaemia in a 52-year-old man who presented with widespread cutaneous necrosis. The diagnosis could not be established early on, as repeated testing for cryoglobulin was negative despite a careful collection method. The diagnosis was made 1 year later, on an incidental full blood smear that revealed crystals, which is an uncommon way to diagnose this condition. We discuss the difficulties we faced in establishing the diagnosis and emphasise the need for repeat cryoglobulin testing in this clinical setting. In such cases, examination of a blood smear should be considered. PMID: 19916973 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3004580 Sun, 01 Nov 2009 00:00:00 +0100 3004580 http://www.medworm.com/index.php?rid=3004579&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19916974%26dopt%3DAbstract Sézary syndrome presenting with 'leonine facies'. Australas J Dermatol. 2009 Nov;50(4):285-8 Authors: Nassem S, Kashyap R, Awasthi NP, Krishnani N, Kumari N A 71-year-old man presented with erythroderma and multiple nodular skin lesions over the face, scalp, upper limbs and trunk. The facial skin was thickened, producing the rare 'leonine facies' appearance. Investigations revealed the presence of atypical lymphoid cells in the peripheral blood, bone marrow and skin. The atypical lymphoid cells in the peripheral blood and bone marrow were positive for helper T-cell antigens (CD4, CD2, CD5 and CD7) on immunophenotyping by flow cytometry. The histopathology of skin showed dermal infiltration by atypical small lymphocytes with epidermotropism. These cells were positive for he... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3004579 Sun, 01 Nov 2009 00:00:00 +0100 3004579 http://www.medworm.com/index.php?rid=3004578&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19916975%26dopt%3DAbstract This report demonstrates excellent cosmetic results and no major postoperative complications or recurrence of the condition after 1 year of follow up for seven patients. Two more patients had been followed up for 1 month at the time this paper was written. Scanned carbon dioxide laser is safe and highly effective treatment for rhinophyma. PMID: 19916975 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3004578 Sun, 01 Nov 2009 00:00:00 +0100 3004578 http://www.medworm.com/index.php?rid=3004577&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19916976%26dopt%3DAbstract We describe a 32-year-old Caucasian man with an acquired naevus of Ota with subtle pigmentation, in which a melanocytic papule developed. The lesion, deceptively, had no clinically suspicious features, but investigation revealed an aggressive cutaneous malignant melanoma, extensive orbital ring melanocytosis and metastatic brain and subsequent liver disease. PMID: 19916976 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3004577 Sun, 01 Nov 2009 00:00:00 +0100 3004577 http://www.medworm.com/index.php?rid=3004576&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19916978%26dopt%3DAbstract Authors: Suarez-Amor O, Monteagudo B, Cabanillas M, de las Heras C PMID: 19916978 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3004576 Sun, 01 Nov 2009 00:00:00 +0100 3004576 http://www.medworm.com/index.php?rid=3004575&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19916979%26dopt%3DAbstract Authors: Gencoglan G, Karaarslan IK, Akalin T, Ozdemir F A 61-year-old woman was referred to our dermoscopy unit for a pigmented lesion that had been present on her left arm for 8 years. The patient did not notice any enlargement or change in colour. On dermoscopy, homogeneous blue pigmentation was seen. The lesion was excised with the pre-operative diagnosis of melanoma, blue naevus and dermatofibroma. Histopathological examination showed a trichilemmal cyst in the mid-dermis. Although homogeneous blue pigmentation on dermoscopy is the hallmark of blue naevus, it may be seen in metastatic melanoma and exceptionally in hemosiderotic and cellular types of dermatofibroma. Trichilemmal cyst should be borne in mind also in the dermoscopic differential diagnosis. PMID: 19916979 [PubMed ... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=3004575 Sun, 01 Nov 2009 00:00:00 +0100 3004575 http://www.medworm.com/index.php?rid=2825137&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19754683%26dopt%3DAbstract Authors: PMID: 19754683 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2825137 Thu, 24 Sep 2009 09:58:04 +0100 2825137 http://www.medworm.com/index.php?rid=2682863&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19659975%26dopt%3DAbstract Authors: Frieden IJ, Rogers M, Garzon MC Infantile haemangiomas are among the most common growths during infancy. Their rapid growth during infancy and vascularity can easily cause confusion with other, less common growths. Part I focussed on other vascular anomalies that can mimic infantile haemangiomas. Part II emphasizes benign growths and malignant conditions that can also cause diagnostic confusion. PMID: 19659975 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2682863 Fri, 31 Jul 2009 23:00:00 +0100 2682863 http://www.medworm.com/index.php?rid=2682862&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19659977%26dopt%3DAbstract Authors: Pua VS, Huilgol S, Hill D A retrospective study of all non-melanoma skin cancers excised by two dermatologists at a private practice in 2004 (excluding Mohs microscopic surgery cases) was conducted. Two hundred and forty-one patients were treated, with a total of 453 tumours excised. The overall incomplete excision rate was 2.2% (10/453). For basal cell cancers, the incomplete excision rate was 1.54% (5/324) and for squamous cell cancers including Bowen's disease the incomplete excision rate was 3.9% (5/129). The majority of repairs were primary closures (82.6%). Although a significant proportion of the tumours were from the head and neck region (45.9%), this study demonstrated that careful patient selection, experience of the surgeon and adherence to recommended excision marg... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2682862 Fri, 31 Jul 2009 23:00:00 +0100 2682862 http://www.medworm.com/index.php?rid=2682861&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19659978%26dopt%3DAbstract Authors: Boone SL, Stapleton J, Turrisi R, Ortiz S, Robinson JK, Mallett KA The aim of this study was to determine the thoroughness of deliberate skin examination by people with a history of melanoma. Patients were randomized into one of two conditions: either to receive the brief educational and skills training intervention alone or as a couple with their spouse or cohabiting partner. Subjects recorded concerning lesions on body maps. At the 4-month visit, a total body skin examination was performed by a dermatologist blinded to the subjects' condition and to their recorded responses. The skin surface was divided according to the region's visibility during skin self-examination and sexual connotations: visible/not sexually sensitive, non-visible/not sexually sensitive and sexually sen... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2682861 Fri, 31 Jul 2009 23:00:00 +0100 2682861 http://www.medworm.com/index.php?rid=2682860&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19659979%26dopt%3DAbstract Authors: Kaur I, Dogra S, Narang T, De D The present study was undertaken to compare the efficacy and safety of thalidomide to that of oral prednisolone in the treatment of moderate to severe type 2 lepra reaction. Sixty patients with a histologically confirmed diagnosis of erythema nodosum leprosum with a clinical score of 4 or more (i.e. moderate to severe type 2 reaction) were randomly allocated to two groups comprising 30 patients each. Group 1 patients were given thalidomide at a dose of 300 mg/day for 1 week and the dose was gradually reduced, and Group 2 received prednisolone 40 mg daily for 2 weeks, which was tapered by 10 mg every 2 weeks. Thalidomide induced a faster clinical response (cutaneous as well as systemic) compared with prednisolone. Patients taking thalidomide had ... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2682860 Fri, 31 Jul 2009 23:00:00 +0100 2682860 http://www.medworm.com/index.php?rid=2682859&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19659980%26dopt%3DAbstract Authors: Yu S, Ming A, Wegman A A 33-year-old woman with a background of thalassaemia major presented with a 3-month history of yellowish plaques on the back of her neck bilaterally and alterations in the texture of the skin in both axillae. Examination of these lesions showed yellowish cobblestone plaques and coalescing papules in both axillae. Pseudoxanthoma elasticum (PXE)-like lesions were confirmed histopathologically. PXE-like lesions in association with thalassaemia major are an uncommon occurrence. Due to the increase in the survival rate of thalassaemia major patients on treatment, the development of these lesions is likely to increase. The histopathological manifestation of these lesions mimics that of hereditary PXE and is associated with severe vascular complications. This ... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2682859 Fri, 31 Jul 2009 23:00:00 +0100 2682859 http://www.medworm.com/index.php?rid=2682858&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19659981%26dopt%3DAbstract We report the case of a woman with severe cicatrizing mucosal LP and ocular symptoms secondary to presumed nasolacrimal duct involvement. We also report the potential for this newly appreciated manifestation of LP to respond to systemic cyclosporin A. PMID: 19659981 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2682858 Fri, 31 Jul 2009 23:00:00 +0100 2682858 http://www.medworm.com/index.php?rid=2682857&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19659982%26dopt%3DAbstract Authors: Kurien A, Henderson C, Lee S A 71-year-old man with chronic renal failure and on peritoneal dialysis presented with recurrence of multiple keratotic nodules along a surgical scar. This was 6 months after the excision of a recurrent keratotic nodule reported as squamous cell carcinoma from the same site. The lesions were initially reported as squamous cell carcinomas, but on review of histology were consistent with keratoacanthomas. One of the keratoacanthomas showed vascular invasion. These responded well to low-dose acitretin at 10 mg three times per week and the patient stayed in remission after 18 months of follow up. PMID: 19659982 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2682857 Fri, 31 Jul 2009 23:00:00 +0100 2682857 http://www.medworm.com/index.php?rid=2682856&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19659983%26dopt%3DAbstract Authors: Preda VA, Frederiksen P, Kossard S A 62-year-old woman presented with a 6-month history of polyarthritis. She had also noted a 2-month history of indurated palmar erythema and increasing bilateral hand swelling and stiffness. A biopsy from the area of palmar erythema showed interstitial fibroplasia within the dermis and subcutis representing a palmar fibromatosis. This presentation appears to belong to the spectrum of palmar fasciitis and polyarthritis syndrome. Rheumatologists have recognised this syndrome as a paraneoplastic disorder and subsequent investigations in our patient revealed an elevated cancer antigen 125 and an inoperable ovarian carcinoma. Indurated palmar erythema is a sign that is not widely recognised by dermatologists as a clue for this paraneoplastic syndr... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2682856 Fri, 31 Jul 2009 23:00:00 +0100 2682856 http://www.medworm.com/index.php?rid=2682855&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19659984%26dopt%3DAbstract Authors: Kieu V, O'Brien T, Yap LM, Baker C, Foley P, Mason G, Prince HM, McCormack C A 48-year-old woman presented with pruritic, scaly, annular plaques over her upper back and chest that were clinically, serologically and histologically characteristic of subacute cutaneous lupus erythematosus (SCLE). She failed to respond to conventional treatment, which included high-dose hydroxychloroquine, methotrexate, prednisolone, chloroquine, acitretin, thalidomide, dapsone and azathioprine. Subsequently treated with intravenous rituximab 375 mg/m(2) weekly for 4 weeks, she remained on adjuvant oral hydrochloroquine 600 mg daily and topical clobetasol propionate 0.05% ointment as required. Clearing of annular plaques was noted 8 weeks after the initial course of rituximab. By 12 weeks there we... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2682855 Fri, 31 Jul 2009 23:00:00 +0100 2682855 http://www.medworm.com/index.php?rid=2682854&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19659985%26dopt%3DAbstract Authors: Thakor AS, Burke A, Handfield-Jones S, Sinha A, Palmer M, Burns A Worldwide, proton pump inhibitors (PPI) are one of the most frequently prescribed drugs; however, up to 70% of patients taking these drugs have no appropriate indication. Although PPI are relatively well tolerated, they are not free from side-effects and several life-threatening complications are associated with them. In the present report, a 43-year-old woman presented to her general practitioner with an erythematous rash over her face and chest, having been started on omeprazole for chronic abdominal bloating. Over the next 24 h she became increasingly unwell and was admitted to hospital with shortness of breath, pyrexia and the rash spreading over her back, arms and legs. Vesicles had now started to appear wi... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2682854 Fri, 31 Jul 2009 23:00:00 +0100 2682854 http://www.medworm.com/index.php?rid=2682853&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19659986%26dopt%3DAbstract Authors: Sriprakash K, Godbolt A A 61-year-old man was treated with imiquimod 5% cream for superficial basal cell carcinoma, five times per week for 13 weeks. This resulted in vitiligo-like depigmentation and poliosis in the area of treatment. This rare side-effect has been noted in previous case reports of imiquimod treatment for both genital warts and superficial basal cell carcinoma. This highlights the importance of such a side-effect being discussed with the patient who is to be treated with imiquimod, particularly in cosmetically sensitive areas. PMID: 19659986 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2682853 Fri, 31 Jul 2009 23:00:00 +0100 2682853 http://www.medworm.com/index.php?rid=2682852&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19659987%26dopt%3DAbstract We describe a 70-year-old woman with psoriasis who noticed darkening of her previously white hair, which also gained a curly appearance after 6 months of acitretin treatment. We present this case to emphasize that acitretin can be added to the list of drugs that induce changes in hair colour and texture. PMID: 19659987 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2682852 Fri, 31 Jul 2009 23:00:00 +0100 2682852 http://www.medworm.com/index.php?rid=2682851&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19659988%26dopt%3DAbstract We report a man with a 6-month history of plaques on his forehead and preauricular area consistent with GF that responded to twice-daily application of topical tacrolimus ointment, and who remains in remission 1 year later. This case supports previous reports of the successful use of topical tacrolimus in treating GF. PMID: 19659988 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2682851 Fri, 31 Jul 2009 23:00:00 +0100 2682851 http://www.medworm.com/index.php?rid=2682850&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19659989%26dopt%3DAbstract We report a 72-year-old woman who presented with a primary melanoma of the umbilicus and periumbilical skin of 4 years' duration. Pathological examination of a biopsy specimen showed Clark's level IV, and tumour thickness 2.3 mm. The patient underwent preoperative lymphatic mapping followed by sentinel lymph node biopsy, and wide local excision of the primary tumour, including its attachment to the peritoneum. Because of the variations in vascularity and the residual embryonal connections of the umbilicus with the peritoneum and other intra-abdominal organs, an aggressive surgical approach is recommended in the management of malignant umbilical tumours. PMID: 19659989 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2682850 Fri, 31 Jul 2009 23:00:00 +0100 2682850 http://www.medworm.com/index.php?rid=2682849&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19659990%26dopt%3DAbstract Authors: Rubegni P, Mandato F, Biagioli M, Fimiani M PMID: 19659990 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2682849 Fri, 31 Jul 2009 23:00:00 +0100 2682849 http://www.medworm.com/index.php?rid=2682848&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19659993%26dopt%3DAbstract Authors: Yoong C, Di Stefani A, Hofmann-Wellenhof R, Campbell T, Soyer HP PMID: 19659993 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2682848 Fri, 31 Jul 2009 23:00:00 +0100 2682848 http://www.medworm.com/index.php?rid=2530949&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19366345%26dopt%3DAbstract Authors: PMID: 19366345 [PubMed - indexed for MEDLINE] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2530949 Thu, 30 Apr 2009 23:00:00 +0100 2530949 http://www.medworm.com/index.php?rid=2530948&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19397559%26dopt%3DAbstract This article focuses on the myriad of diagnostic mimics of haemangiomas, including other vascular anomalies, benign growths, and malignancies. PMID: 19397559 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2530948 Thu, 30 Apr 2009 23:00:00 +0100 2530948 http://www.medworm.com/index.php?rid=2530947&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19397561%26dopt%3DAbstract In this study, patients attending the eczema workshop had a greater improvement in eczema severity thanpatients attending a dermatologist-led clinic, supporting collaborative models of service provision. PMID: 19397561 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2530947 Thu, 30 Apr 2009 23:00:00 +0100 2530947 http://www.medworm.com/index.php?rid=2530946&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19397562%26dopt%3DAbstract Authors: Tang MB, Tan ES, Tian EA, Loo SC, Chua SH Oral isotretinoin is a highly effective treatment for refractory nodulocystic acne. However, it can be associated with serious adverse effects such as teratogenicity and hepatitis. Inadequate cumulative dosing may also result in reduced therapeutic efficacy and higher disease relapse. A preliminary audit had previously revealed a poor and inconsistent adherence to local isotretinoin prescribing guidelines by physicians. To achieve greater than 90% adherence to isotretinoin guidelines for all acne patients prescribed systemic isotretinoin at the National Skin Centre, Singapore, key areas and the reasons for non-adherence were identified. A specifically designed 'one-stop' electronic isotretinoin chart was launched within the electronic ... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2530946 Thu, 30 Apr 2009 23:00:00 +0100 2530946 http://www.medworm.com/index.php?rid=2530945&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19397563%26dopt%3DAbstract Authors: Yazdabadi A, Green J, Sinclair R A 9-year-old prepubertal girl with female pattern hair loss treated with spironolactone 100 mg orally per day had objective improvement demonstrated by regrowth observed clinically and on comparison of pre- and post-treatment stereotactic scalp photographs taken 6 months apart. PMID: 19397563 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2530945 Thu, 30 Apr 2009 23:00:00 +0100 2530945 http://www.medworm.com/index.php?rid=2530944&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19397564%26dopt%3DAbstract We present a case of ILVEN occurring on the vulva and perianal region of a 6-year-old girl. The lesion was initially thought to be an area of lichenified dermatitis; however, treatment with even super-potent topical corticosteroids did not significantly improve the inflammation. A biopsy was performed and histopathological examination showed characteristic features. ILVEN is frequently refractory to topical treatment and surgical excision of lesions may be an option for relief of symptoms. ILVEN occasionally presents in the inguinogenital region and in this area may, like many vulval naevi, be misdiagnosed as vulvitis, psoriasis, genital warts or sexual abuse. PMID: 19397564 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2530944 Thu, 30 Apr 2009 23:00:00 +0100 2530944 http://www.medworm.com/index.php?rid=2530943&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19397565%26dopt%3DAbstract We describe a case of FDE due to paracetamol presenting as a chronic erosive vulvitis in an older woman taking multiple medications. Diagnosis was delayed because paracetamol is available without prescription, taken intermittently and may be omitted from the clinical history. Cessation of paracetamol led to prompt resolution of symptoms. Consideration should be given to paracetamol as a cause of FDE presenting as a chronic erosive vulvitis. PMID: 19397565 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2530943 Thu, 30 Apr 2009 23:00:00 +0100 2530943 http://www.medworm.com/index.php?rid=2530942&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19397566%26dopt%3DAbstract Authors: Mackenzie KA, Maurice PD A 35-year-old woman was referred to the dedicated dermatology clinic for RTR. She underwent her first renal transplant at 18 years of age due to chronic renal failure following reflux nephropathy of the single right kidney (left kidney agenesis). She has since then had two further transplants. During clinical examination she was noted to have at least 16 basal cell carcinomas (BCC) and there are records in the case notes of 10 BCC having being excised and confirmed histologically in the past. By contrast, she had only had two squamous cell carcinomas (SCC) excised. She was also noted to have distinctive facial features, a kyphoscoliosis and palmar pits, and a diagnosis of Gorlin's (naevoid BCC) syndrome (GS) was made. Although immunosuppression may hav... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2530942 Thu, 30 Apr 2009 23:00:00 +0100 2530942 http://www.medworm.com/index.php?rid=2530941&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19397567%26dopt%3DAbstract Authors: Derraik JG, Rademaker M There are a number of reports in the literature of allergic contact dermatitis as a result of exposure to the sawdust and plant parts of Grevillea robusta. While this tree is prevalent in New Zealand, there seems to have been no previous published accounts of contact dermatitis, although anecdotal evidence indicates that such cases may be common. Two brief case reports are provided regarding severe phytodermatitis to G. robusta among professional arborists in New Zealand. As with other common plants capable of inducing allergic contact dermatitis, greater awareness among arborists, orchardists, forestry workers, gardeners, and health professionals will likely result in a reduction of cases. PMID: 19397567 [PubMed - in process] (Source: The Australas... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2530941 Thu, 30 Apr 2009 23:00:00 +0100 2530941 http://www.medworm.com/index.php?rid=2530940&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19397568%26dopt%3DAbstract Authors: Rodrigues M, McCormack C, Yap LM, Prince HM, Roberts H, Williams R, Foley P A 40-year-old woman presented with a prolonged history of recurrent crops of erythematous papules and nodules on her abdomen, arms and legs. Histological examination of a cutaneous biopsy revealed Type A lymphomatoid papulosis. Over a 3-year period, some of the patient's lesions had proven to be resistant to treatment with topical and intralesional corticosteroids and systemic agents including methotrexate, tetracycline and nicotinamide. These resistant lesions were treated with two sessions of methyl aminolevulinate photodynamic therapy given 1 week apart. Review 11 months post-photodynamic therapy demonstrated complete clinical clearance at the treatment site. While photodynamic therapy is considered... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2530940 Thu, 30 Apr 2009 23:00:00 +0100 2530940 http://www.medworm.com/index.php?rid=2530939&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19397569%26dopt%3DAbstract We describe a patient with a solitary mastocytoma arising at a site of trauma. The patient was born with the umbilical cord wrapped around her right thigh and subsequently developed a solitary mastocytoma in the exact site and distribution of this injury. The pathogenesis of mast cell proliferation in solitary mastocytoma is not completely understood. Cytokines released after injury, such as stem cell factor, may stimulate the proliferation of mast cells, as well as fibroblasts and melanocytes to form a mastocytoma. Mast cells in a newborn may be more sensitive to stem cell factor in the presence of cytokines released after injury due to an increased density of c-kit receptors. We present our patient and review the literature to support a hypothesis that this condition represents a reactiv... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2530939 Thu, 30 Apr 2009 23:00:00 +0100 2530939 http://www.medworm.com/index.php?rid=2530938&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19397570%26dopt%3DAbstract Authors: Koh C, Sugo E, Wargon O Infantile haemangiomas are usually not present at birth. This is a case of a female infant with an atypical congenital vascular tumour present at birth which ulcerated in the first few days of life, involuted over several months and showed histopathological features in keeping with either an involuting GLUT-1 positive infantile haemangioma or a reticular haemangioma of infancy. The initial clinical presentation was atypical for an infantile haemangiomas and for a congenital haemangioma, however the histopathology and immunohistochemistry assisted with confirmation of the diagnosis. Vacuum-assisted closure (VAC) therapy aided in the complete healing of the ulcerated infantile haemangioma which was not achievable with conventional dressings. PMID: 193... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2530938 Thu, 30 Apr 2009 23:00:00 +0100 2530938 http://www.medworm.com/index.php?rid=2530937&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19397571%26dopt%3DAbstract Authors: Cheah S, DeKoven J A 37 year-old-woman presented for cosmetic removal of a 7-mm (diameter) cherry angioma on her right anterior thigh. Various treatment options were discussed and removal of the lesion using pulsed-dye laser was carried out. The patient returned 5 weeks later complaining of bleeding from the treatment site, which on examination showed a 23 x 23-mm friable nodular lesion with the typical appearance of a pyogenic granuloma. This lesion was removed by shave excision, curettage and electrodessication. Histopathological examination confirmed the diagnosis of pyogenic granuloma. This is a rare occurrence post pulsed-dye laser therapy that physicians may choose to discuss with patients prior to performing this procedure. PMID: 19397571 [PubMed - in process] (Sour... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2530937 Thu, 30 Apr 2009 23:00:00 +0100 2530937 http://www.medworm.com/index.php?rid=2530936&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19397572%26dopt%3DAbstract We report a 21-year-old Hispanic woman with a slowly enlarging 1.7 x 2.3-cm subungual and periungual pigmented plaque present since birth on her right second toe. Initial biopsy was consistent with a blue naevus of the cellular type and, given the recent clinical change and periungual extension, complete excision was recommended. The entire nail unit was resected down to periosteum with prior avulsion of the nail plate. Reconstruction was performed with a full-thickness skin graft. Follow up at 1 year revealed well-healed graft and donor sites with complete return of function. We present a case of a congenital subungual and periungual blue naevus of the cellular type and review the literature on this rare presentation of a congenital blue naevus. PMID: 19397572 [PubMed - in process] (S... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2530936 Thu, 30 Apr 2009 23:00:00 +0100 2530936 http://www.medworm.com/index.php?rid=2153583&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19178500%26dopt%3DAbstract Authors: Garg T, Ramchander , Srihar R, Gupta TP PMID: 19178500 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2153583 Sun, 01 Feb 2009 05:00:00 +0100 2153583 http://www.medworm.com/index.php?rid=2148289&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19178485%26dopt%3DAbstract Authors: Marghoob AA, Changchien L, Defazio J, Dessio WC, Malvehy J, Zalaudek I, Halpern AC, Scope A Due to its particularly lethal nature and tendency to affect relatively young individuals, the timely diagnosis of melanoma remains of paramount importance for clinicians and their patients. Unfortunately, melanomas can mimic benign lesions that are overwhelmingly more common in the population than are melanomas, and misdiagnosis or delay in diagnosis of melanoma can occur. Misdiagnosis of melanoma serves as one of the most common causes for malpractice litigation brought against medical practitioners. In this review we describe seven clinical scenarios that represent challenges in melanoma diagnosis and discuss potential strategies for avoiding the errors that commonly give rise to tho... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2148289 Sat, 31 Jan 2009 14:29:35 +0100 2148289 http://www.medworm.com/index.php?rid=2148288&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19178486%26dopt%3DAbstract Authors: PMID: 19178486 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2148288 Sat, 31 Jan 2009 14:29:31 +0100 2148288 http://www.medworm.com/index.php?rid=2148287&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19178487%26dopt%3DAbstract Authors: Siller G, Gebauer K, Welburn P, Katsamas J, Ogbourne SM The sap of the plant Euphorbia peplus is a traditional remedy for skin conditions, including actinic keratosis. The active constituent of the sap is ingenol mebutate (ingenol-3-angelate), formerly known as PEP005. This randomized, double-blind, vehicle-controlled, phase IIa study investigated the safety (and secondarily the efficacy) of two applications of ingenol mebutate gel in 58 patients with biopsy-confirmed actinic keratosis. Five preselected lesions were treated with ingenol mebutate gel, 0.0025%, 0.01% or 0.05%, or vehicle gel, on days 1 and 2 (Arm A) or days 1 and 8 (Arm B). There were no significant differences in tolerability or efficacy between Arms A and B. Treatment was well tolerated. The most common local ... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2148287 Sat, 31 Jan 2009 14:29:25 +0100 2148287 http://www.medworm.com/index.php?rid=2148286&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19178488%26dopt%3DAbstract Authors: Chan BC, Patel DC Dermatological surgery performed in an outpatient setting is common and generally perceived as safe, but the potential for serious adverse events does exist. Furthermore, there is a current lack of guidelines regarding preoperative and intraoperative monitoring of such patients. This is a retrospective study that involved a written questionnaire sent to current practising New Zealand dermatologists. Aspects investigated include their practice relating to preoperative assessments and intraoperative monitoring during standard dermatological procedures, and the resulting rate of adverse events. We found that most respondents performed dermatological procedures in dedicated theatres in outpatient clinics. The majority of survey respondents would screen for and op... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2148286 Sat, 31 Jan 2009 14:29:19 +0100 2148286 http://www.medworm.com/index.php?rid=2148285&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19178489%26dopt%3DAbstract Authors: Windsor ML, Eisenberg M, Gordon-Thomson C, Moore GP Studies of skin graft behaviour in rodent excisional wound models are limited by the dominance of wound contracture and graft sloughing as primary healing responses. To slow skin contraction, polytetrafluoroethylene (Teflon) rings were inserted into dorso-lateral full-thickness wounds in SCID mice. Cultured skin substitutes (OrCel), composed of cultured human keratinocytes and fibroblasts in a bovine collagen sponge, were implanted within the rings. Examination and histology of grafts 14 days later showed graft take in four of six recipients, with 90% epithelialization and wound contraction of 31-47%. Immunohistochemical studies, using human-specific antisera to distinguish graft from host tissues, showed that regenerated tis... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2148285 Sat, 31 Jan 2009 14:29:13 +0100 2148285 http://www.medworm.com/index.php?rid=2148284&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19178490%26dopt%3DAbstract We report two cases of leprosy in southern Australia that presented to the dermatology outpatients' department within a 4-month period. The presentation of the first case was complex, making the correct diagnosis difficult. Both cases involved immigrants from South-East Asia, were classified as multi-bacillary leprosy as defined by the World Health Organization, and were commenced on the recommended multiple drug therapy. The ensuing clinical course was complicated, with both cases developing Type 1 leprosy reactions. The first case also developed the rare but serious dapsone-induced delayed hypersensitivity reaction. PMID: 19178490 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2148284 Sat, 31 Jan 2009 14:29:01 +0100 2148284 http://www.medworm.com/index.php?rid=2148283&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19178491%26dopt%3DAbstract Authors: Cheng H, Geist DE, Piperdi M, Virk R, Piperdi B A 62-year-old woman with a pre-existing psoriasis was treated with oral imatinib (400 mg/day) for a metastatic gastrointestinal stromal tumour. Within 4 weeks of starting therapy, she developed a guttate psoriasis flare. The eruption markedly improved within 2 weeks following cessation of imatinib. However, it recurred when imatinib was recommenced. She has been able to continue on imatinib (400 mg/day) with low-dose oral methotrexate (12.5 mg/week) controlling the psoriasis. PMID: 19178491 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2148283 Sat, 31 Jan 2009 14:28:52 +0100 2148283 http://www.medworm.com/index.php?rid=2148282&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19178492%26dopt%3DAbstract Authors: Holmes C, Chong AH, Tabrizi SN, Downes N, Nindl I A 43 year-old immunosuppressed woman presented with a widespread macular scaly rash, clinically and histologically consistent with epidermodysplasia verruciformis. She had no family history of epidermodysplasia verruciformis. Human papillomavirus typing was performed on both biopsied skin from clinical lesions and on plucked body hairs. The lesional skin from the arm and knee showed predominantly human papillomavirus-20 and -47 respectively. Human papillomavirus genotyping from the hair follicles revealed that human papillomavirus-20 had the highest viral load, irrespective of body site. PMID: 19178492 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2148282 Sat, 31 Jan 2009 14:28:40 +0100 2148282 http://www.medworm.com/index.php?rid=2148281&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19178493%26dopt%3DAbstract We report a case of a 46-year-old man with ulcerative colitis being treated with oral prednisolone and azathioprine. Two weeks after the initiation of azathioprine he presented with fever, fatigue, myalgias and arthralgias and a painful cutaneous eruption that was most marked in a sun-exposed distribution. This was accompanied by loose, non-bloody diarrhoea. Histopathological assessment of a skin biopsy supported a diagnosis of a neutrophilic dermatosis. The azathioprine was temporarily withheld and oral prednisolone was increased as it was thought that the neutrophilic dermatosis was associated with the underlying ulcerative colitis. The patient's symptoms and cutaneous eruption resolved quickly and azathioprine was re-introduced. Within 24 h, systemic symptoms returned along with a flori... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2148281 Sat, 31 Jan 2009 14:28:28 +0100 2148281 http://www.medworm.com/index.php?rid=2148280&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19178494%26dopt%3DAbstract Authors: Weinel S, Malone J, Jain D, Callen JP A 47-year-old woman with a history of breast cancer presented with eruptive cutaneous nodules on the trunk and extremities. Treatment for her breast cancer had included surgery, radiation and chemotherapy with doxorubicin and cyclophosphamide. Biopsy of the skin lesions revealed leukaemia cutis, which led to the discovery of acute myelogenous leukaemia. This was felt to be primarily induced by doxorubicin. Treatment included induction chemotherapy in preparation for a bone marrow transplant, which resulted in the disappearance of the cutaneous lesions. However, the patient later succumbed to her leukaemia. PMID: 19178494 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2148280 Sat, 31 Jan 2009 14:28:14 +0100 2148280 http://www.medworm.com/index.php?rid=2148279&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19178495%26dopt%3DAbstract We report a patient with pyoderma gangrenosum successfully treated with intravenous immunoglobulin. He had previously been treated for 4 years with high-dose corticosteroids and had developed insulin-dependent diabetes mellitus. Multiple corticosteroid-sparing agents had failed or were contraindicated. He developed no adverse effects from intravenous immunoglobulin, which allowed reduction of his prednisone to 3 mg/day, and his ulcer has completely healed. PMID: 19178495 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2148279 Sat, 31 Jan 2009 14:28:06 +0100 2148279 http://www.medworm.com/index.php?rid=2148278&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19178496%26dopt%3DAbstract Authors: Cherian P, Kumarasinghe P An 88-year-old man presented to the dermatology outpatient clinic with an 11-month history of a rapidly growing mass overlying a clavicular fracture site. The lesion was 8 x 6 cm, painful, fixed to deeper structures and ulcerated. Superficial and deep biopsies yielded invasive basal cell carcinoma. Imaging demonstrated extensive soft tissue invasion into muscle, bone and potentially into the lung parenchyma. Due to complications arising from subsequent diagnostic procedures, the patient declined further invasive tests. The cutaneous lesion was treated with palliative radiotherapy. We explore the literature regarding the tumorigenic effects of peri-fracture cytokines on the biological behaviour of basal cell neoplasms. PMID: 19178496 [PubMed - in p... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2148278 Sat, 31 Jan 2009 14:27:54 +0100 2148278 http://www.medworm.com/index.php?rid=2148277&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19178497%26dopt%3DAbstract Authors: Kumar S, Weedon D, De'ambrosis B Primary cutaneous angioplasmocellular hyperplasia is a plasmacellular infiltrate that has been reported only once previously in the literature, in a report of a case affecting two Latin American patients. In the present case, a systemically well 62-year-old Caucasian man presented with a nodule on the back of the neck. Histology showed a vascular proliferative process with an abundance of plasma cells in the stroma. There has been no recurrence of the lesion 2 years following curettage and diathermy. The clinicopathological presentation is consistent with primary cutaneous angioplasmocellular hyperplasia. PMID: 19178497 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2148277 Sat, 31 Jan 2009 14:27:46 +0100 2148277 http://www.medworm.com/index.php?rid=2148276&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19178498%26dopt%3DAbstract Authors: Oakley A, Rademaker M PMID: 19178498 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2148276 Sat, 31 Jan 2009 14:27:43 +0100 2148276 http://www.medworm.com/index.php?rid=2148275&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19178499%26dopt%3DAbstract Authors: Watson A PMID: 19178499 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2148275 Sat, 31 Jan 2009 14:27:40 +0100 2148275 http://www.medworm.com/index.php?rid=2148274&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19178500%26dopt%3DAbstract Authors: Garg T, Chander R, Srihar R, Gupta TP PMID: 19178500 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2148274 Sat, 31 Jan 2009 14:27:36 +0100 2148274 http://www.medworm.com/index.php?rid=2148273&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19178501%26dopt%3DAbstract Authors: Aspres N PMID: 19178501 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2148273 Sat, 31 Jan 2009 14:27:33 +0100 2148273 http://www.medworm.com/index.php?rid=2148272&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19178502%26dopt%3DAbstract Authors: Callan A PMID: 19178502 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2148272 Sat, 31 Jan 2009 14:27:30 +0100 2148272 http://www.medworm.com/index.php?rid=2148271&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19178503%26dopt%3DAbstract Authors: PMID: 19178503 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=2148271 Sat, 31 Jan 2009 14:27:27 +0100 2148271 http://www.medworm.com/index.php?rid=1881217&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18855776%26dopt%3DAbstract Authors: Gilmore SJ Medical practitioners should be familiar with the basic principles of statistical testing and analysis, as the critical evaluation of clinical trials is an essential component to the effective practise of evidence-based medicine. Practitioners also need to be able to identify unethical trial design. The aim of this review is to facilitate an understanding of inferential methodology by introducing some of the basic principles involved in the critical analysis of trial design and interpretation. PMID: 18855776 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1881217 Thu, 16 Oct 2008 17:23:39 +0100 1881217 http://www.medworm.com/index.php?rid=1881215&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18855778%26dopt%3DAbstract This article reviews the factors that contribute to therapy-related leukaemia and the development of leukaemia cutis. PMID: 18855778 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1881215 Thu, 16 Oct 2008 17:23:33 +0100 1881215 http://www.medworm.com/index.php?rid=1881214&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18855779%26dopt%3DAbstract Authors: Cook-Norris RH, Zic JA, Boyd AS We undertook a clinical and histopathological analysis of patients presenting with Meyerson's naevi. Eleven patients with the characteristic histological features of a Meyerson's naevus were identified over a 5-year period. Diagnostic criteria included epidermal spongiosis and a dermal inflammatory infiltrate associated with a banal junctional or compound naevus. Cases were excluded if naevus cells showed moderate to severe atypia or regression. Patients were contacted by phone and interviewed regarding their lesions. The most common clinical appearance was a solitary, pruritic, erythematous eruption encircling a pre-existing pigmented naevus. The trunk and proximal upper extremities were preferentially affected. Only one clinician listed Meyers... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1881214 Thu, 16 Oct 2008 17:23:30 +0100 1881214 http://www.medworm.com/index.php?rid=1881213&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18855780%26dopt%3DAbstract We describe the use of total circumferential margin control with vertical and horizontal permanent sections for the treatment of lentigo maligna that we believe is simple, effective and reproducible. PMID: 18855780 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1881213 Thu, 16 Oct 2008 17:23:27 +0100 1881213 http://www.medworm.com/index.php?rid=1881212&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18855781%26dopt%3DAbstract Authors: Tan WP, Tan AW, Ee HL, Kumarasinghe P, Tan SH Clinical and microscopic pigmentation may affect the treatment outcomes in basal cell carcinoma. However, there have not been any in-depth histopathological comparisons between clinically pigmented and non-pigmented basal cell carcinomas with regards to microscopic melanization. The aims of our study were to determine the proportion of pigmented basal cell carcinomas presenting to the National Skin Centre in Singapore, to characterize the histological pattern of melanization and to perform a semi-quantitative analysis of the degree of microscopic melanization of the tumours. Patients with clinical features and histologically confirmed basal cell carcinomas were recruited. Demographic data and clinical characteristics were recorded ... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1881212 Thu, 16 Oct 2008 17:23:23 +0100 1881212 http://www.medworm.com/index.php?rid=1881211&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18855782%26dopt%3DAbstract We present three cases of Kawasaki disease in which an annular eruption was the predominant cutaneous finding. The provisional diagnosis was Stevens-Johnson syndrome. However, the annular lesions were not typical of Stevens-Johnson syndrome: the lips were crusted without mucosal ulceration and the conjunctivitis was non-purulent without corneal erosions. Dermatologists are often involved in the initial assessment of this multisystem disease and should be aware of the variety of cutaneous manifestations, as rapid treatment is known to decrease morbidity and mortality. PMID: 18855782 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1881211 Thu, 16 Oct 2008 17:23:20 +0100 1881211 http://www.medworm.com/index.php?rid=1881210&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18855783%26dopt%3DAbstract Authors: DeAmbrosis K, Nicklin J, Yong-Gee S Four cases of vulval basal cell carcinoma were identified in multiparous females aged 46-78 years. Symptoms included discomfort and pruritus ranging from 6 weeks to 4 years in duration. Such symptoms occurred in the context of a pink vulval plaque. The non-specific symptoms, in the context of the particular anatomical site, led to late presentation. Subsequent treatment in all cases involved wide local excision following incisional biopsy. No recurrence has been documented after a minimum follow-up period of 12 months. PMID: 18855783 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1881210 Thu, 16 Oct 2008 17:23:17 +0100 1881210 http://www.medworm.com/index.php?rid=1881209&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18855784%26dopt%3DAbstract We report the successful treatment of severe long-standing erosive vulvovaginal lichen planus in four adult female patients using 2.5-7.5 mg of oral methotrexate once weekly in conjunction with topical clobetasol dipropionate 0.05% ointment and tacrolimus 0.03-0.10% ointment. All cases experienced improvement in symptoms and healing of lesions within 4-8 weeks. Methotrexate was well tolerated and no adverse events have been observed in any of the patients at follow up 4-6 months later. PMID: 18855784 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1881209 Thu, 16 Oct 2008 17:23:13 +0100 1881209 http://www.medworm.com/index.php?rid=1881208&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18855785%26dopt%3DAbstract Authors: McHugh A, Siller G, Williamson R, Faulkner C A 22-year-old woman presented with recurrent non-ulcerating skin nodules overlying the great saphenous vein on the anteromedial lower legs. Histology showed a granulomatous phlebitis, and polymerase chain reaction performed on lesional skin detected DNA specific for Mycobacterium tuberculosis. The lesions resolved with anti-tuberculous therapy. This case may be a further example of nodular granulomatous phlebitis, a phlebitic tuberculid. PMID: 18855785 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1881208 Thu, 16 Oct 2008 17:23:08 +0100 1881208 http://www.medworm.com/index.php?rid=1881207&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18855786%26dopt%3DAbstract Authors: Ho V, Banney L, Falhammar H A 62-year-old Malaysian woman presented with a constellation of skin signs including alopecia, hyperpigmentation and nail dystrophy. On questioning, a history of diarrhoea, taste disturbance and weight loss was found. The onset of these changes coincided with the administration of thyroxine prescribed for a benign multinodular goitre. Hormonal investigations showed no abnormality and no underlying malignancy was found. Investigation of the diarrhoea showed a protein-losing enteropathy with generalized intestinal polyposis and non-specific histology. A diagnosis of Cronkhite-Canada syndrome was made. Treatment with prednisone and nutritional support has been partially effective. PMID: 18855786 [PubMed - in process] (Source: The Australasian Journ... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1881207 Thu, 16 Oct 2008 17:23:05 +0100 1881207 http://www.medworm.com/index.php?rid=1881206&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18855787%26dopt%3DAbstract Authors: Pearce V, Horton JJ A 28-year-old man from the Philippines presented with multiple papules and plaques symmetrically distributed on the arms and legs. This was associated with worsening paraesthesia of the hands and feet. A right common peroneal nerve decompression had been performed 2 years earlier. He was diagnosed with multibacillary leprosy on skin biopsy and subsequently treated with oral rifampicin, clofazamine and dapsone. PMID: 18855787 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1881206 Thu, 16 Oct 2008 17:23:02 +0100 1881206 http://www.medworm.com/index.php?rid=1881205&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18855788%26dopt%3DAbstract Authors: Leow LJ, Goh BK A case of halo congenital naevus is reported on the chest of a 56-year-old Asian woman with pre-existing vitiligo. The naevus measured 3.5 cm x 2 cm and underwent depigmentation around its periphery. Dermoscopic examination showed coarse pigment in the darker centre of the naevus and depigmentation in the surrounding halo. Light microscopy showed well-formed naevus cell nests with coarse melanin granules in the papillary dermis, and surrounding fibrosis. Melanocytes extended into reticular dermis, consistent with a congenital growth pattern. There was no evidence of malignancy. The epidermis was of normal appearance. S100 staining highlighted melanocytes in the dermis. Basal melanocytes were retained at the periphery of the naevus. Based on the clinical history... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1881205 Thu, 16 Oct 2008 17:22:59 +0100 1881205 http://www.medworm.com/index.php?rid=1881204&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18855789%26dopt%3DAbstract Authors: Sriprakash K, Yong-Gee S An 87 year old woman with dementia presented with multiple digitate hyperkeratoses on her face, limbs and chest. She had a previous diagnosis of a paraproteinaemia, with a serum monoclonal band of immunoglobulin G-kappa and anaemia being detected. The skin biopsy of these hyperkeratotic lesions was characterized by multiple areas of orthokeratosis with immunoglobulin deposition. There was no association with hair follicles. These multiple digitate hyperkeratoses have been associated with underlying systemic disorders including malignancies. PMID: 18855789 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1881204 Thu, 16 Oct 2008 17:22:56 +0100 1881204 http://www.medworm.com/index.php?rid=1881203&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18855790%26dopt%3DAbstract Authors: Dunn R, Dolianitis C A 41-year-old man with prolidase deficiency has had chronic leg ulcers and recurrent cellulitis for most of his life. Until recently he had been hospitalized at least annually for this and suffered significant morbidity as a result. Since commencing topical 5% proline in white soft paraffin ointment to treat the leg ulcers, there has been marked improvement in the ulcers and decreased frequency of hospitalizations for cellulitis. This lends further support to the use of topical proline in the treatment of patients with skin ulcers secondary to prolidase deficiency. PMID: 18855790 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1881203 Thu, 16 Oct 2008 17:22:53 +0100 1881203 http://www.medworm.com/index.php?rid=1881202&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18855791%26dopt%3DAbstract Authors: Tritton SM, Shumack S, Fischer G A 60-year-old man presented with a 3-week history of lethargy, anorexia, breathlessness at rest, nausea and vomiting. He had a 5-year history of an undisclosed, enlarging, pigmented mass on his penis. He refused biopsy of this lesion. Fine-needle aspirate of an enlarged inguinal lymph node histologically confirmed a diagnosis of melanoma and widespread metastases were demonstrated by radiological imaging. The patient succumbed to disease within 8 days of diagnosis. Primary penile melanoma, albeit rare, is an important and sensitive dermatological problem, often leading to delayed presentation. PMID: 18855791 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1881202 Thu, 16 Oct 2008 17:22:49 +0100 1881202 http://www.medworm.com/index.php?rid=1881201&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18855792%26dopt%3DAbstract We report a case of complex regional pain syndrome developing in a 57-year-old woman after minor skin surgery in the sole of her right foot. This was diagnosed and treated in its early phase with sympathetic blockade using guanethedine with complete recovery of symptoms. PMID: 18855792 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1881201 Thu, 16 Oct 2008 17:22:47 +0100 1881201 http://www.medworm.com/index.php?rid=1881200&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18855793%26dopt%3DAbstract Authors: Ayva S, Erkek E, Atasoy P Two patients presented with cutaneous lesions clinically typical of psoriasis. The first case was a 38-year-old man and the second was a 51-year-old woman. To confirm the diagnosis, 4-mm punch biopsy samples were obtained from both patients from the lesions on the knees. Histology in both cases was in favour of psoriasis and also revealed empty vacuoles in the papillary dermis, concentrated at sites of intense lymphocyte infiltration. The empty vacuoles resembled true fat cells or fat globules. They did not reveal positive immunostaining with CD34 antigen, suggesting that they were not lined by endothelial cells. Final histological diagnosis was psoriasis associated with dermal vacuolization. PMID: 18855793 [PubMed - in process] (Source: The Austr... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1881200 Thu, 16 Oct 2008 17:22:43 +0100 1881200 http://www.medworm.com/index.php?rid=1881199&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18855794%26dopt%3DAbstract Authors: Cakmak SK, Gönül M, Gül U, Unal T, Dağlar E PMID: 18855794 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1881199 Thu, 16 Oct 2008 17:22:39 +0100 1881199 http://www.medworm.com/index.php?rid=1881198&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18855795%26dopt%3DAbstract Authors: Yun SK, Park J, Lee DW, Ahn M, Kim HU PMID: 18855795 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1881198 Thu, 16 Oct 2008 17:22:36 +0100 1881198 http://www.medworm.com/index.php?rid=1881197&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18855796%26dopt%3DAbstract Authors: Yip L, Harrison S, Foley P PMID: 18855796 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1881197 Thu, 16 Oct 2008 17:22:34 +0100 1881197 http://www.medworm.com/index.php?rid=1881218&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18855775%26dopt%3DAbstract Authors: PMID: 18855775 [PubMed - as supplied by publisher] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1881218 Mon, 06 Oct 2008 04:00:00 +0100 1881218 http://www.medworm.com/index.php?rid=1881216&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18855777%26dopt%3DAbstract Authors: PMID: 18855777 [PubMed - as supplied by publisher] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1881216 Mon, 06 Oct 2008 04:00:00 +0100 1881216 http://www.medworm.com/index.php?rid=1881196&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18855797%26dopt%3DAbstract Authors: Doyle JA PMID: 18855797 [PubMed - as supplied by publisher] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1881196 Mon, 06 Oct 2008 04:00:00 +0100 1881196 http://www.medworm.com/index.php?rid=1881195&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18855798%26dopt%3DAbstract THE AUSTRALASIAN COLLEGE OF DERMATOLOGISTS. Australas J Dermatol. 2008 Oct 6;49(4):253 Authors: PMID: 18855798 [PubMed - as supplied by publisher] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1881195 Mon, 06 Oct 2008 04:00:00 +0100 1881195 http://www.medworm.com/index.php?rid=1643502&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18638218%26dopt%3DAbstract Authors: Borchard KL, Orchard D Topical therapies are the mainstay in the treatment of atopic dermatitis, and are effective in the majority of patients with mild and localized disease. In patients with widespread or recalcitrant moderate to severe dermatitis, systemic therapies may be required. The frequently used systemic therapies are immunosuppressants, immune response modifiers, anti-inflammatories, antihistamines, and antibiotics. In this article, the indications and scientific support for the use of these medications is reviewed. PMID: 18638218 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1643502 Tue, 22 Jul 2008 18:48:01 +0100 1643502 http://www.medworm.com/index.php?rid=1643501&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18638219%26dopt%3DAbstract Authors: PMID: 18638219 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1643501 Tue, 22 Jul 2008 18:47:57 +0100 1643501 http://www.medworm.com/index.php?rid=1643500&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18638220%26dopt%3DAbstract In conclusion, significant numbers of normal healthy subjects have circulating autoantibodies to basement membrane proteins, chiefly BP180 detectable by immunoblot, but these do not bind the NC16A domain. PMID: 18638220 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1643500 Tue, 22 Jul 2008 18:47:55 +0100 1643500 http://www.medworm.com/index.php?rid=1643499&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18638221%26dopt%3DAbstract Authors: Raasch BA, Buettner PG An omnibus telephone survey of 1200 adult Australians determined self-reported prevalence of and attitudes to sunburn and sunspots, knowledge of the term solar keratosis and prevalence of skin checks. Half reported they had been sunburnt in the previous year. Seventy-eight per cent considered sunburn to be extremely or very serious, while 73% considered sunspots as serious or very serious. While 29% reported currently having sunspots, 69% had never heard of the term solar keratosis, 30% had never had a skin check and 28% had their last skin check more than 12 months ago. Respondents 18-29 years old (odds ration [OR] = 2.6; P = 0.002) and men (OR = 2.4; P < 0.001) were most likely to experience multiple sunburn. Persons living in capital cities (OR = 0... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1643499 Tue, 22 Jul 2008 18:47:49 +0100 1643499 http://www.medworm.com/index.php?rid=1643498&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18638222%26dopt%3DAbstract We describe a series of six patients with superficial cutaneous haemorrhages of the feet, including a classical case of black heel (talon noir) and other similar cases with diverse clinical presentations that do not match the typical description of that process. The main differences lay in production mechanism, morphology and location. The causes of these 'atypical' lesions were: burns with hot sand, friction against the rough edge of a swimming pool, wearing new shoes, jogging, or pricking a blister with a needle. Clinically, they consisted of isolated or multiple, small, large or linear, brown or black lesions located in areas that did not include the convex part of the heel, in which talon noir usually appears; on the contrary, the lesions affected the back third of the soles, the toes,... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1643498 Tue, 22 Jul 2008 18:47:46 +0100 1643498 http://www.medworm.com/index.php?rid=1643497&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18638223%26dopt%3DAbstract Authors: Yip L, Harrison S, Foley P Differences in mode of action between biologic agents could explain why one agent is more efficacious than another in the treatment of recalcitrant and erythrodermic flares of chronic plaque psoriasis. Here, we present our experience using a case series of three patients with chronic plaque psoriasis who showed consistent and similar responses to three different biologic agents. All three patients who were refractory to efalizumab developed erythrodermic flares 2-12 weeks after a direct switch to etanercept. Switching from efalizumab to etanercept could provoke paradoxical flaring of psoriasis, which might be prevented by transitioning to systemic agents. The erythrodermic flares in all three patients responded dramatically to infliximab with marked ... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1643497 Tue, 22 Jul 2008 18:47:43 +0100 1643497 http://www.medworm.com/index.php?rid=1643496&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18638224%26dopt%3DAbstract Authors: Thoo CH, Graf N, Hogan P A 10-year-old Kenyan girl presented with a 9-month history of a persistent, painful eruption of multiple, tender, non-ulcerated, pigmented nodules involving the calves, shins and soles of the feet. She had recurring fevers particularly at night, lethargy, weight loss and a persistent non-productive cough. The Mantoux test was positive. Chest X-ray revealed mild peribronchial thickening in the hilar region but no evidence of hilar lymphadenopathy, consolidation and/or cavitation suggestive of tuberculosis. Sputum and gastric washings were negative for acid-fast bacilli. Histology on a skin biopsy showed a granulomatous panniculitis with no histological evidence of Mycobacterium tuberculosis, consistent with erythema induratum. In view of her constitutio... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1643496 Tue, 22 Jul 2008 18:47:41 +0100 1643496 http://www.medworm.com/index.php?rid=1643495&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18638225%26dopt%3DAbstract Authors: Howes R, Girgis L, Kossard S A 52-year-old woman with a 6-year history of a persistent non-pruritic cutaneous annular eruption, forming polycyclic and arcuate plaques that commenced as erythematous papules and nodules, is presented. Lethargy and arthralgia were associated symptoms. We have followed this patient for the last 3 years, and during this period she has continued to have a florid annular eruption of unknown cause. Laboratory tests, including an eosinophil count, examination of stool samples for parasites, and a computed tomography scan of the chest, abdomen and pelvis, failed to detect any abnormalities. Skin biopsies demonstrated a superficial to deep cellular infiltrate consisting of numerous eosinophils, with lymphocytes and isolated neutrophils. Eosinophilic dust... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1643495 Tue, 22 Jul 2008 18:47:36 +0100 1643495 http://www.medworm.com/index.php?rid=1643494&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18638226%26dopt%3DAbstract Authors: Braue A, Dolianitis C, Varigos G A 37-year-old male developed facial papules 6 months post renal-pancreatic transplant. Histological findings were consistent with localized papular mucinosis; electrophoresis showed no paraprotein. A trial of erbium and aura lasers, at ablative doses, produced no improvement. Independent treatments with oral doxycycline, itraconazole, acitretin, and isotretinoin also had no effect. The facial papules improved spontaneously, 2 years after first presentation and 8 months after treatment ceased. The patient remains clear of lesions. PMID: 18638226 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1643494 Tue, 22 Jul 2008 18:47:34 +0100 1643494 http://www.medworm.com/index.php?rid=1643493&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18638227%26dopt%3DAbstract Authors: Sandoval-Tress C, Nava-Jiménez G A 38-year-old man presented with axillary freckling, multiple café au lait macules and neurofibromas on the scalp, trunk and extremities. In addition, he had a patch of white hair on the right parieto-occipital area overlying a scalp neurofibroma. He was diagnosed with poliosis circumscripta associated with neurofibromatosis 1. PMID: 18638227 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1643493 Tue, 22 Jul 2008 18:47:29 +0100 1643493 http://www.medworm.com/index.php?rid=1643492&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18638228%26dopt%3DAbstract Authors: Kwong RA, Kossard S A 54-year-old woman presented with a 6-month history of a tender and swollen plaque appearing as a panniculitis affecting the left pretibial area. The initial histopathology revealed dermal and subcutaneous inflammation with interstitial histiocytes and mucinosis suggestive of either granuloma annulare or necrobiosis lipoidica. Over the subsequent 6 months the plaque grew progressively, despite treatment with topical corticosteroids under occlusion. Distal to the plaque reduced sensation developed in the limb. Biopsies of the nodular areas now revealed a dense dermal infiltrate of atypical spindle cells within a prominent myxoid stroma and a pleomorphic multinucleated epithelioid cell component. These features were those of an intermediate grade myxofibrosa... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1643492 Tue, 22 Jul 2008 18:47:22 +0100 1643492 http://www.medworm.com/index.php?rid=1643491&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18638229%26dopt%3DAbstract Authors: Lucas A, Belinchón I, Pérez-Crespo M, Mataix J, Betlloch I PMID: 18638229 [PubMed - in process] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1643491 Tue, 22 Jul 2008 18:47:18 +0100 1643491 http://www.medworm.com/index.php?rid=1643490&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18638230%26dopt%3DAbstract Authors: Thai KE PMID: 18638230 [PubMed - as supplied by publisher] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1643490 Tue, 22 Jul 2008 18:47:15 +0100 1643490 http://www.medworm.com/index.php?rid=1643489&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18638231%26dopt%3DAbstract Authors: Gordon L PMID: 18638231 [PubMed - as supplied by publisher] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1643489 Tue, 22 Jul 2008 18:47:12 +0100 1643489 http://www.medworm.com/index.php?rid=1643488&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18638232%26dopt%3DAbstract Authors: Chong AH PMID: 18638232 [PubMed - as supplied by publisher] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1643488 Tue, 22 Jul 2008 18:47:10 +0100 1643488 http://www.medworm.com/index.php?rid=1588879&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18412804%26dopt%3DAbstract Authors: McGrath JA One of the principal functions of human skin is to form an effective mechanical barrier against the external environment. This involves the maturation and death of epidermal keratinocytes as well as the assembly of a complex network of differentially and spatially expressed proteins, glycoproteins and lipids into the keratinocyte cell membrane and surrounding extracellular space. In 2006, the key role of the granular cell layer protein filaggrin (filament-aggregating protein) in maintaining the skin barrier was determined with the identification of loss-of-function mutations in the profilaggrin gene (FLG). These mutations have been shown to be the cause of ichthyosis vulgaris and a major risk factor for the development of atopic dermatitis, asthma associated with at... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1588879 Thu, 01 May 2008 04:00:00 +0100 1588879 http://www.medworm.com/index.php?rid=1588878&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18412805%26dopt%3DAbstract Authors: Davarian S, Kalantari KK, Rezasoltani A, Rahimi A The purpose of this study was to investigate the efficacy and persistence of the hypohidrosis induced by iontophoresis of botulinum toxin type A in patients with palmar hyperhidrosis. Eight patients with severe palmar hyperhidrosis participated in this study. Iontophoresis of botulinum toxin was applied to the patients' dominant (right) hand and the other hand was the control treated with normal saline. Gravimetry and iodine-starch tests were performed to evaluate the rate of sweating. The evaluation sessions were at baseline, 2 and 4 days, 1, 2, 3, 4, 8 and 12 weeks after treatment. The patients were also asked to fill out the Dermatology Life Quality Index questionnaire at 2, 4, 8 and 12 weeks after treatment. The mean sweati... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1588878 Thu, 01 May 2008 04:00:00 +0100 1588878 http://www.medworm.com/index.php?rid=1588877&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18412806%26dopt%3DAbstract Authors: Haverhoek E, Reid C, Gordon L, Marshman G, Wood J, Selva-Nayagam P Forty-three patients with the primary complaint of vulval pruritus were recruited to take part in this prospective patch-testing study. A detailed questionnaire was administered to each and patch testing to an extended battery of allergens was undertaken. This included the European standard series, preservatives, corticosteroids and a battery of common over-the-counter topical vulval treatments. Analysis of demographic data and prior treatments used, and various other parameters, were studied in the context of patch-test results. This prospective study reports a very high rate of contact sensitivity in patients presenting with vulval pruritus, with 81.4% of those tested having at least one contact allergen dete... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1588877 Thu, 01 May 2008 04:00:00 +0100 1588877 http://www.medworm.com/index.php?rid=1588876&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18412807%26dopt%3DAbstract Authors: Subramaniam K, Debinski H, Heenan P A 75-year-old woman presented with pink papules over the trunk and limbs. Over the next few weeks, the papules became umbilicated and then developed into porcelain-white lesions with a rose or violaceous rim. A biopsy of one of these lesions revealed superficial and deep dermal lymphohistiocytic inflammation, mainly perivascular with a central zone of infarction consistent with Degos' disease. Three years later, she presented with increasing abdominal pain, anaemia, raised inflammatory markers and an abdominal bruit. Angiography showed splanchnic vessel stenosis possibly secondary to vasculitis and she underwent successful balloon dilatation. Treatment with prednisolone was commenced. There has been no recurrence of lesions in the 12 months ... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1588876 Thu, 01 May 2008 04:00:00 +0100 1588876 http://www.medworm.com/index.php?rid=1588875&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18412808%26dopt%3DAbstract Authors: Ludgate MW, Greig DE A 29-year-old woman with a 4-week history of systemic lupus erythematosus presented acutely with a severe generalized tense vesicular and bullous eruption with involvement of mucosal surfaces. At the time of her initial diagnosis of systemic lupus erythematosus, she had declined treatment, preferring to explore complementary medical therapies. Skin biopsy showed subepidermal blister formation with inflammation at the dermoepidermal junction. Direct immunofluorescence revealed strongly positive linear deposition of IgG and IgM, and positive linear granular deposition of IgA along the basement membrane zone. Electron microscopy showed that the level of the basement membrane split was below the lamina densa. A diagnosis of bullous systemic lupus erythematosus... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1588875 Thu, 01 May 2008 04:00:00 +0100 1588875 http://www.medworm.com/index.php?rid=1588874&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18412809%26dopt%3DAbstract Authors: Foley S, Gibbs H, Muir J A 40-year-old male smoker presented with a 3-week history of painful digital infarction involving the hands. Histology was unhelpful, showing lichen simplex chronicus. A provisional diagnosis of a vasculitic disease was made. Treatment included aspirin, azathioprine, iloprost, methylprednisolone, nifedipine and prednisolone. After failure of these treatments an alternative clinical diagnosis of Buerger's disease was made. Treatment was to advise the patient of the importance of continuing to abstain from smoking, to perform bilateral video-assisted thoracoscopic sympathectomies and to commence folate supplementation. This led to marked improvement of his symptoms and healing of the digital infarction. PMID: 18412809 [PubMed - indexed for MEDLINE] (... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1588874 Thu, 01 May 2008 04:00:00 +0100 1588874 http://www.medworm.com/index.php?rid=1588873&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18412810%26dopt%3DAbstract This report adds further evidence that cutaneous chancroid should be considered in the evaluation of skin ulcers in the south Pacific. PMID: 18412810 [PubMed - indexed for MEDLINE] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1588873 Thu, 01 May 2008 04:00:00 +0100 1588873 http://www.medworm.com/index.php?rid=1588872&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18412811%26dopt%3DAbstract We report a case of B-cell post-transplant lymphoproliferative disorder in a 57-year-old female 19 years postrenal transplant patient who presented with multiple, progressive, painful ulcerated necrotic papules and nodules over the left leg. Histopathological examination showed diffuse infiltration of the dermis by large atypical B-lymphoid cells, with a negative in situ hybridization test for Epstein-Barr virus. Gastrointestinal involvement was evident by the presence of atypical lymphoid cells in the peritoneal fluid. She only had partial response to localized radiotherapy and intravenous rituximab and died 4 months later of septicaemia. Unusual features highlighted in this case include the very late onset of disease 19 years post-transplant, Epstein-Barr virus negativity and the aggress... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1588872 Thu, 01 May 2008 04:00:00 +0100 1588872 http://www.medworm.com/index.php?rid=1588871&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18412812%26dopt%3DAbstract Authors: Starritt E, Lee S Erythroplasia of Queyrat of the glans penis developed in a 79-year-old uncircumcised man on a background of biopsy proven Zoon's plasma cell balanitis affecting the same site on the glans. The Zoon's plasma cell balanitis had been treated with topical pimecrolimus for 1 month prior to the development of clinically evident erythroplasia of Queyrat. He was subsequently treated with topical 5-fluorouracil 5% for 2 weeks, which resulted in clinical clearance. He has since been circumcised. PMID: 18412812 [PubMed - indexed for MEDLINE] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1588871 Thu, 01 May 2008 04:00:00 +0100 1588871 http://www.medworm.com/index.php?rid=1588870&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18412813%26dopt%3DAbstract Authors: Leow LJ, Sinclair PA, Horton JJ Unusual large dermatofibromata are reported in a 40-year-old man and a 48-year-old man, who both presented with plaques on a lower limb. The largest plaque in each case was well-defined, reddish brown, indurated and measured 50 mm x 30 mm and 70 mm x 40 mm, respectively. Several satellite lesions were present around the large plaques. Dermoscopic examination showed diffuse homogenous pigmentation in the absence of other diagnostic criteria for dermatofibroma. Light microscopy of biopsies from each patient displayed similar features. There was a dermal proliferation of fibrohistiocytic cells that entrapped intervening thickened collagen fibres. The overlying epidermis was acanthotic, and in some instances this showed basal hyperpigmentation. Ther... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1588870 Thu, 01 May 2008 04:00:00 +0100 1588870 http://www.medworm.com/index.php?rid=1588869&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18412814%26dopt%3DAbstract We present two cases of lichen amyloidosus treated with retinoids. A 57-year-old Vietnamese woman has had extensive generalized recalcitrant lichen amyloidosus for 23 years. Treatment with oral etretinate (25 mg/day) for 3 years, and later oral acitretin (10 mg/day) for the past 10 years, has controlled the pruritus and flattened the hyperkeratotic papules. Whenever the acitretin was ceased her symptoms flared within weeks. On each occasion reintroduction of acitretin was effective within 1-2 months. The second case is that of a 51-year-old Australian Aboriginal woman who had a 2-year history of lichen amyloidosus affecting her lower legs. A 2-month course of oral acitretin (25 mg b.d.) produced a marked improvement in both the pruritus and hyperkeratotic papules. She was then lost to foll... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1588869 Thu, 01 May 2008 04:00:00 +0100 1588869 http://www.medworm.com/index.php?rid=1588868&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18412815%26dopt%3DAbstract Authors: Burkhart CG, Burkhart CN A 33-year-old male experienced three episodes of urticaria precipitated by exposure to a hidden source of ampicillin. Each occurrence coincided temporally with his girlfriend taking ampicillin for a chest cold and/or allergies. We postulate that he was exposed to ampicillin in the body fluids of his sexual partner. PMID: 18412815 [PubMed - indexed for MEDLINE] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1588868 Thu, 01 May 2008 04:00:00 +0100 1588868 http://www.medworm.com/index.php?rid=1588867&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18412816%26dopt%3DAbstract Authors: Thoo CH, Freeman S A 42-year-old woman presented with a hypersensitivity reaction after the ingestion of a small amount of fresh mango gelato. She developed itchy palpable purpuric lesions over her arms, legs, neck and abdomen 4 days after ingestion. The lesions persisted for 5 weeks despite treatment with betamethasone-17 valerate 0.05% ointment and avoidance of mango. Resolution of these lesions was eventually achieved with continuing treatment. The patient denied any prior contact with mango skin but had experienced previous sensitizing reactions to mango flesh. Patch testing was strongly positive to mango skin and mango flesh. Skin-prick testing was negative. This case describes a systemic contact dermatitis to mango flesh, an entity less common than allergic contact derma... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1588867 Thu, 01 May 2008 04:00:00 +0100 1588867 http://www.medworm.com/index.php?rid=1588866&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18412803%26dopt%3DAbstract Authors: PMID: 18412803 [PubMed - indexed for MEDLINE] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1588866 Thu, 01 May 2008 04:00:00 +0100 1588866 http://www.medworm.com/index.php?rid=1588896&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18186838%26dopt%3DAbstract Authors: Slodownik D, Lee A, Nixon R Irritant contact dermatitis is the most common form of contact dermatitis, and yet is often overlooked. Recent progress in understanding the pathogenesis has reignited the interest of clinicians in this area of dermatology. Irritant contact dermatitis is not a homogenous entity, but rather a number of subtypes contributing to different clinical presentations. The diagnosis of irritant contact dermatitis is often clinical, and may only be possible after the exclusion of allergic contact dermatitis with patch testing. There is no readily available diagnostic test. There is an incomplete understanding of the factors which lead to the development of cumulative irritant contact dermatitis and persistent postoccupational dermatitis. We have used the exper... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1588896 Fri, 01 Feb 2008 05:00:00 +0100 1588896 http://www.medworm.com/index.php?rid=1588895&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18186839%26dopt%3DAbstract Authors: Chia AL, Simonova G, Dutta B, Lim A, Shumack S A retrospective audit of melanoma clinical diagnoses was undertaken for a group of 35 Australian dermatologists. This was compared with the histological diagnoses. In a 1-year period, 195 of the 686 clinically suspicious lesions were histologically confirmed as melanoma. Therefore, the number needed to treat for histological referrals for melanoma is four for this group of dermatologists. In addition, we found that the sensitivity for the diagnosis of melanoma was 89.1% if we consider all lesions that are possibly clinically suspicious of melanoma. Our results suggest that the clinical diagnosis of melanoma may not be difficult for lesions that are clinically characteristic. PMID: 18186839 [PubMed - indexed for MEDLINE] (Sourc... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1588895 Fri, 01 Feb 2008 05:00:00 +0100 1588895 http://www.medworm.com/index.php?rid=1588894&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18186840%26dopt%3DAbstract Authors: Lasocki AL, Kelly RI A 33-year-old man presented with a 3-month history of a widespread pigmented purpuric eruption over his trunk and limbs. The clinical presentation and histology were consistent with a diagnosis of Schamberg's disease. The rash initially cleared following a short course of oral prednisolone at 25 mg daily for 3 weeks, which was weaned over the subsequent 4 weeks. Topical mometasone furoate ointment 0.1% daily was also applied to active areas. The rash recurred when prednisolone was reduced to below 5 mg per day. To prevent a further recurrence with weaning prednisolone, narrowband UVB therapy was commenced three times per week. The patient was continued on UV therapy over the next 5 months. The rash would flare after 2 to 3 weeks without treatment. The freq... The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1588894 Fri, 01 Feb 2008 05:00:00 +0100 1588894 http://www.medworm.com/index.php?rid=1588893&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18186841%26dopt%3DAbstract Authors: Gild R, Clay CD A 16-year-old girl presented with a 3-year history of painful swelling and wrinkling of her palms on exposure to water. Physical examination, after less than 2 min of immersion, showed thickening and exaggerated wrinkling of the palms giving a whitish pebbly appearance. Aquagenic wrinkling of the palms was diagnosed. The patient was tested for the common cystic fibrosis mutations, and was found to be heterozygous for the arg117His cystic fibrosis mutation. Her sweat test was normal. PMID: 18186841 [PubMed - indexed for MEDLINE] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1588893 Fri, 01 Feb 2008 05:00:00 +0100 1588893 http://www.medworm.com/index.php?rid=1588892&cid=s_37563_12_f&fid=37563&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18186842%26dopt%3DAbstract Authors: Rajpara SM, Siddha SK, Ormerod AD, Kerr KM, Kolhe PS A 73-year-old man presented with fistulizing cutaneous Crohn's disease of the penis and perianal area without involvement of the gastrointestinal tract. The disease failed to respond to topical clobetasol propionate and oral cyclosporin and methotrexate. A combination treatment of minocycline, thalidomide and prednisolone brought the disease under control and induced remission. Surgery with excision and skin grafting were required to produce cure. PMID: 18186842 [PubMed - indexed for MEDLINE] (Source: The Australasian Journal of Dermatology) The Australasian Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=1588892 Fri, 01 Feb 2008 05:00:00 +0100 1588892