MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'The Indian Journal of Medical Research' source. Thu, 29 Dec 2011 06:45:43 +0100 http://www.medworm.com/index.php?rid=5544224&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22199093%26dopt%3DAbstract Authors: Yates T, Davies MJ, Schwarz PE, Khunti K PMID: 22199093 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5544224 Tue, 01 Nov 2011 04:00:00 +0100 5544224 http://www.medworm.com/index.php?rid=5544223&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22199094%26dopt%3DAbstract Authors: Singh S, Katoch VM PMID: 22199094 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5544223 Tue, 01 Nov 2011 04:00:00 +0100 5544223 http://www.medworm.com/index.php?rid=5544222&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22199095%26dopt%3DAbstract Authors: Iovannisci DM PMID: 22199095 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5544222 Tue, 01 Nov 2011 04:00:00 +0100 5544222 http://www.medworm.com/index.php?rid=5544221&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22199096%26dopt%3DAbstract Authors: Qadeer I PMID: 22199096 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5544221 Tue, 01 Nov 2011 04:00:00 +0100 5544221 http://www.medworm.com/index.php?rid=5544220&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22199097%26dopt%3DAbstract Authors: Mota PC PMID: 22199097 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5544220 Tue, 01 Nov 2011 04:00:00 +0100 5544220 http://www.medworm.com/index.php?rid=5544219&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22199098%26dopt%3DAbstract Authors: El-Hazmi MA, Al-Hazmi AM, Warsy AS Abstract The sickle cell (HbS) gene occurs at a variable frequency in the Middle Eastern Arab countries, with characteristic distribution patterns and representing an overall picture of blood genetic disorders in the region. The origin of the gene has been debated, but studies using β-globin gene haplotypes have ascertained that there were multiple origins for HbS. In some regions the HbS gene is common and exhibits polymorphism, while the reverse is true in others. A common causative factor for the high prevalence and maintenance of HbS and thalassaemia genes is malaria endemicity. The HbS gene also co-exists with other haemoglobin variants and thalassaemia genes and the resulting clinical state is referred to as sickle cell disease (SC... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5544219 Tue, 01 Nov 2011 04:00:00 +0100 5544219 http://www.medworm.com/index.php?rid=5544218&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22199099%26dopt%3DAbstract Authors: Mathur P Abstract Health care associated infections are drawing increasing attention from patients, insurers, governments and regulatory bodies. This is not only because of the magnitude of the problem in terms of the associated morbidity, mortality and cost of treatment, but also due to the growing recognition that most of these are preventable. The medical community is witnessing in tandem unprecedented advancements in the understanding of pathophysiology of infectious diseases and the global spread of multi-drug resistant infections in health care set-ups. These factors, compounded by the paucity of availability of new antimicrobials have necessitated a re-look into the role of basic practices of infection prevention in modern day health care. There is now undisputed ev... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5544218 Tue, 01 Nov 2011 04:00:00 +0100 5544218 http://www.medworm.com/index.php?rid=5544217&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22199100%26dopt%3DAbstract Authors: Lingaiah K, Sosalagere DM, Mysore SR, Krishnamurthy B, Narayanappa D, Nallur RB Abstract Background & objectives: Cardiac malformations in the young constitute a major portion of clinically significant birth defects. Congenital heart disease (CHD) is a common congenital cardiac birth defect, affecting nearly 1 per cent of all live births. Patent ductus arteriosus (PDA) is clinically significant foetal circulation anomaly, second most common form of CHD which constitutes approximately 10 per cent of total CHDs. The study aimed to screen for TFAP2B mutations in CHD patients of Mysore. Methods: With informed consent, 100 clinically diagnosed CHD patients and 50 healthy controls in Mysore, south India, were recruited for the analysis of screening of mutations. MassARRAY an... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5544217 Tue, 01 Nov 2011 04:00:00 +0100 5544217 http://www.medworm.com/index.php?rid=5544216&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22199101%26dopt%3DAbstract Discussions (19 in AP; 29 in Orissa), and 61 Key Informant Interviews with healthcare providers (22 in AP; 39 in Orissa). Results: In AP, 69.5 per cent of respondents accessed non-degree allopathic practitioners (NDAPs) practicing in or near their village; in Orissa, 40.2 per cent chose first curative contact with NDAPs and 36.2 per cent with traditional healers. In AP, all NDAPs were private practitioners, in Orissa some pharmacists and nurses employed in health facilities, also practiced privately. Respondents explained their choice by proximity and providers' readiness to make house-calls when needed. Less than a quarter of respondents chose qualified doctors as their first point of call: mostly private practitioners in AP, and public practitioners in Orissa. Amongst those who chose a ... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5544216 Tue, 01 Nov 2011 04:00:00 +0100 5544216 http://www.medworm.com/index.php?rid=5544215&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22199102%26dopt%3DAbstract Authors: Agrawal S, Sharma SK, Sreenivas V, Lakshmy R Abstract Background & objectives: Obstructive sleep apnoea (OSA) is known to be associated with cardiovascular risk factors and metabolic syndrome (MS). The burden of MS in patients with OSA in India is unknown. We investigated the prevalence of MS and its components in a cross-sectional study in patients with and without OSA in a hospital-based population of a tertiary health care centre in New Delhi, India. Methods: Consecutive patients undergoing overnight polysomnography in the Sleep Laboratory of the Department of Internal Medicine of All India Institute of Medical Sciences (AIIMS) hospital, New Delhi, were studied. Anthropometry and body composition analysis, blood pressure (BP), fasting blood glucose, insulin resista... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5544215 Tue, 01 Nov 2011 04:00:00 +0100 5544215 http://www.medworm.com/index.php?rid=5544214&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22199103%26dopt%3DAbstract This study was carried out to explore the level of engagement of north Indian students in health promoting behaviours; to determine their sense of coherence scores; and to ascertain the determinants of health promoting behaviours of these students. Methods: A cross-sectional study was done in four randomly selected colleges of Chandigarh during 2007-2008 in 200 students (100 male, 100 female). Their health promoting lifestyle profile (HPLP) and sense of coherence (SOC) scores were estimated using interviews. The data were analyzed using Pearson's product moment correlation, and also stepwise linear regression analysis. Results: Mean HPLP and SOC scores of the students were 138.69 and 130.87, respectively. Females cared more about their health than males. Male students were more involved in... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5544214 Tue, 01 Nov 2011 04:00:00 +0100 5544214 http://www.medworm.com/index.php?rid=5544213&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22199104%26dopt%3DAbstract Authors: Bandyopadhyay A Abstract Background & objectives: Pulmonary function tests have been evolved as clinical tools in diagnosis, management and follow up of respiratory diseases as it provides objective information about the status of an individual's respiratory system. The present study was aimed to evaluate pulmonary function among the male and female young Kelantanese Malaysians of Kota Bharu, Malaysia, and to compare the data with other populations. Methods: A total of 128 (64 males, 64 females) non-smoking healthy young subjects were randomly sampled for the study from the Kelantanese students' population of the University Sains Malaysia, Kota Bharu Campus, Kelantan, Malaysia. The study population (20-25 yr age group) had similar socio-economic background. Each subjec... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5544213 Tue, 01 Nov 2011 04:00:00 +0100 5544213 http://www.medworm.com/index.php?rid=5544212&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22199105%26dopt%3DAbstract Authors: Anantharaman R, Bhansali A, Bhadada SK, Kohli HS, Walia R, Shanmugasundar G, Jayaprakash P Abstract Background & objectives: Angiotensin converting enzyme inhibitors (ACEIs) or angiotensin receptor blockers (ARBs) have been used to normalize the blood pressure and the dipping pattern in patients with type 1 diabetes mellitus (T1DM) and nephropathy. However, there are no data on the effect of the dual blockade on the dipping pattern in these subjects. We therefore, carried out this study to evaluate the effect of administrating an ACEI followed by ARB in the optimum doses in T1DM patients with nephropathy on 24 h blood pressure (BP) profile and nocturnal dipping pattern. Methods: An open label interventional pilot study was done during a one year period involving 30 con... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5544212 Tue, 01 Nov 2011 04:00:00 +0100 5544212 http://www.medworm.com/index.php?rid=5544211&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22199106%26dopt%3DAbstract Authors: Duary RK, Rajput YS, Batish VK, Grover S Abstract Background & objectives: Adherence of bacteria to epithelial cells and mucosal surfaces is a key criterion for selection of probiotic. We assessed the adhesion property of selected indigenous probiotic Lactobacillus strains based on their hydrophobicity and ability to adhere to human epithelial cells. Methods: Five human faecal Lactobacillus isolates, one from buffalo milk and one from cheese were assessed for hydrophobicity following the microbial adhesion to hydrocarbons (MATH) method and colonization potentials based on their adherence to Caco2 and HT-29 colonic adenocarcinomal human intestinal epithelial cell lines. Lactobacillus strains that adhered to Caco2 and HT-29 cell lines were quantified by plating after try... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5544211 Tue, 01 Nov 2011 04:00:00 +0100 5544211 http://www.medworm.com/index.php?rid=5544210&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22199107%26dopt%3DAbstract Authors: Hettihewa LM Abstract Background & objectives: Dendritic cells (DCs) are potent antigen presenting cells which proceed from immature to a mature stage during their differentiation. There are several methods of obtaining long lasting mature antigen expressing DCs and different methods show different levels of antigen expressions. We investigated bone marrow derived DCs for the degree of maturation and genetically engineered antigen presentation in the presence of interleukin-4 (IL-4) as a maturity enhancer. Methods: DCs and transfected retrovirus were cultured together in the presence of granulocyte-macrophage colony stimulating factor (GMCSF)-IL4, GMCSF +IL4, lipopolysaccharide (LPS). B 7.1, B7.2 and CD11c were measured by the degree of immune fluorescence using enhan... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5544210 Tue, 01 Nov 2011 04:00:00 +0100 5544210 http://www.medworm.com/index.php?rid=5544209&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22199108%26dopt%3DAbstract This study was aimed to demonstrate the expression of 2 kDa antimicrobial peptide which was identified and purified from female genital tract tissues using chromatographic techniques. Methods: Low molecular weight proteins were isolated from human female reproductive tract tissues obtained from premenopausal women. Antimicrobial activity of these LMW proteins was assessed against different reproductive tract pathogens viz., Neisseria gonorrhoeae, Group B streptococcus, Gardnerella vaginalis, Escherechia coli and Candida albicans. The expression of these peptides were also documented in reproductive tract tissues with the help of hyperimmune sera raised against the rabbits. The purified peptide was characterized by N-terminal sequencing. Results: Immunohistochemical and immunofluorescence s... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5544209 Tue, 01 Nov 2011 04:00:00 +0100 5544209 http://www.medworm.com/index.php?rid=5544208&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22199109%26dopt%3DAbstract This study demonstrated the real time monitoring and non-invasive analysis of progression of infection and pharmacological efficacy of drugs. These models may be useful for pre-clinical discovery of new antibiotics. PMID: 22199109 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5544208 Tue, 01 Nov 2011 04:00:00 +0100 5544208 http://www.medworm.com/index.php?rid=5544207&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22199110%26dopt%3DAbstract Conclusion: M.w (as immunomodulator) has beneficial therapeutic effect as an adjunct to chemotherapy. PMID: 22199110 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5544207 Tue, 01 Nov 2011 04:00:00 +0100 5544207 http://www.medworm.com/index.php?rid=5544206&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22199111%26dopt%3DAbstract Authors: Thati V, Shivannavar CT, Gaddad SM Abstract Background & objectives: Multidrug resistant methicillin-resistant Staphylococcus aureus (MRSA) is a major cause of nosocomial and community acquired infections and is on the rise. The glycopeptide vancomycin has been proposed as the drug of choice for treating such infections. The present study aimed at identifying the vancomycin resistance both phenotypically and genotypically among the MRSA isolates from two tertiary care hospitals in Hyderabad, south India. Methods: MRSA were isolated and identified from different clinical samples collected from ICUs of tertiary care hospitals in Hyderabad using conventional methods. Antibiogram of the isolates and vancomycin MIC were determined following CLSI guidelines. vanA was amplifi... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5544206 Tue, 01 Nov 2011 04:00:00 +0100 5544206 http://www.medworm.com/index.php?rid=5544205&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22199112%26dopt%3DAbstract Authors: Sharma U, Singh D, Kumar P, Dobhal MP, Singh S Abstract Background & objectives: The severe toxicity, exorbitant cost and emerging resistance of Leishmania species against most of the currently used drugs underscores the urgent need for the alternative drugs. The present study evaluates in vitro anti-leishmanial activity of Plumeria bicolor and its isolated compounds. Methods: The in vitro anti-parasitic activity of chloroform extract of Plumeria bicolor, plumericin and isoplumericin were tested alongwith appropriate controls against promastigote and amastigote forms of Leishmania donovani using 96 well microtiter plate. The concentration used for assessing the anti-leishmanial activity of extract of Plumeria bicolor and both isolated compounds were 100 μg/ml and 15 ... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5544205 Tue, 01 Nov 2011 04:00:00 +0100 5544205 http://www.medworm.com/index.php?rid=5544204&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22199113%26dopt%3DAbstract Authors: Yu WG, Xu G, Ren GJ, Xu X, Yuan HQ, Qi XL, Tian KL Abstract Background & objectives: Curcuma longa (turmeric) has a long history of use in Ayurvedic medicine as a treatment for inflammatory conditions. The purpose of the present study was to investigate the preventive effects of curcumin against acute pancreatitis (AP) induced by caerulein in mouse and to elucidate possible mechanism of curcumin action. Methods: Curcumin (50 mg/kg/day) was intraperitoneally injected to Kun Ming male mice for 6 days, followed by injection of caerulein to induce AP. GW9662 (0.3 mg/kg), a specific peroxisome proliferator-activated receptor gamma (PPARγ) antagonist, was intravenously injected along with curcumin. Murine macrophage RAW264.7 cells were treated with 100 μmol/l curcumin for ... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5544204 Tue, 01 Nov 2011 04:00:00 +0100 5544204 http://www.medworm.com/index.php?rid=5544203&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22199114%26dopt%3DAbstract In this study, we used breast thermography to estimate the tumour contour from the breast skin surface temperature. Methods: We proposed a framework called infrared thermography based image construction (ITBIC) to estimate tumour parameters such as size and depth from cancerous breast skin surface temperature data. Markov Chain Monte Carlo method was used to enhance the accuracy of estimation in order to reflect clearly realistic situation. Results: We validated our method experimentally using Watermelon and Agar models. For the Watermelon experiment error in estimation of size and depth parameters was 1.5 and 3.8 per cent respectively. For the Agar model it was 0 and 8 per cent respectively. Further, thermal breast screening was done on female volunteers and compared it with the magnetic ... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5544203 Tue, 01 Nov 2011 04:00:00 +0100 5544203 http://www.medworm.com/index.php?rid=5544202&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D22199115%26dopt%3DAbstract Authors: Kermode M, Armstrong G, Waribam S PMID: 22199115 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5544202 Tue, 01 Nov 2011 04:00:00 +0100 5544202 http://www.medworm.com/index.php?rid=5308663&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21985804%26dopt%3DAbstract Authors: Colombo A PMID: 21985804 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5308663 Thu, 01 Sep 2011 04:00:00 +0100 5308663 http://www.medworm.com/index.php?rid=5308662&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21985805%26dopt%3DAbstract Authors: John TJ, Shah NK PMID: 21985805 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5308662 Thu, 01 Sep 2011 04:00:00 +0100 5308662 http://www.medworm.com/index.php?rid=5308661&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21985806%26dopt%3DAbstract Authors: Kesavan R, Kukreti R, Adithan C PMID: 21985806 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5308661 Thu, 01 Sep 2011 04:00:00 +0100 5308661 http://www.medworm.com/index.php?rid=5308660&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21985807%26dopt%3DAbstract Authors: John TJ, Verghese VP PMID: 21985807 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5308660 Thu, 01 Sep 2011 04:00:00 +0100 5308660 http://www.medworm.com/index.php?rid=5308659&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21985808%26dopt%3DAbstract Authors: McKenna D, Sheth J Abstract Umbilical cord blood (UCB) has been shown to be a suitable source of haematopoietic stem cells (HSCs) for haematopoietic reconstitution. An increase in the number of UCB transplants indicates an expansion of utility in a broad spectrum of disease conditions. Along with the advantages, UCB also has limitations, and hence several investigators are working to further optimize UCB for this use. Beyond haematopoietic transplantation, additional potential applications of UCB include immunotherapy, tissue engineering and regenerative medicine. UCB banking has improved with time largely due to involvement of professional organizations and their published standards. However, accreditation of these organizations remains voluntary, and in India three of te... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5308659 Thu, 01 Sep 2011 04:00:00 +0100 5308659 http://www.medworm.com/index.php?rid=5308658&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21985809%26dopt%3DAbstract Authors: Zhang L, Zong ZY, Liu YB, Ye H, Lv XJ Abstract Background & objectives : Diagnosis for Mycoplasma pneumoniae usually relies on serological tests. PCR technology has some advantages but also limitations. The optimal selection for these tests still needs discussion. This paper reviews the overall diagnostic accuracy of PCR versus serological assays for diagnosis of M. pneumoniae infections and to identify factors associated with heterogeneity of results. Methods : MEDLINE and Embase databases were searched. Articles meeting the selection criteria were retrieved for data collection and analysis. Studies were assessed for methodological quality using QUADAS. Hierarchial summary receiver operating characteristic (HSROC) model was used to estimate summary ROC curve. Results ... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5308658 Thu, 01 Sep 2011 04:00:00 +0100 5308658 http://www.medworm.com/index.php?rid=5308657&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21985810%26dopt%3DAbstract This report summarizes the situation as it is known regarding antibiotic use and growing resistance in India and recommends short and long term actions. Recommendations aim at (i) reducing the need for antibiotics; (ii) lowering resistance-enhancing drug pressure through improved antibiotic targeting, and (iii) eliminating antibiotic use for growth promotion in agriculture. The highest priority needs to be given to (i) national surveillance of antibiotic resistance and antibiotic use - better information to underpin decisions on standard treatment guidelines, education and other actions, as well as to monitor changes over time; (ii) increasing the use of diagnostic tests, which necessitates behavioural changes and improvements in microbiology laboratory capacity; (iii) setting up and/or st... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5308657 Thu, 01 Sep 2011 04:00:00 +0100 5308657 http://www.medworm.com/index.php?rid=5308656&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21985811%26dopt%3DAbstract In this study we aimed to investigate the relationship between the genetic polymorphism of cytochrome P450 genes, namely CYP2C9 and CYP2C19 with multiple drug resistance in epilepsy patients. Methods : A total of 402 patients with epilepsy were enrolled in this study; 128 were drug resistant and 274 were drug responsive. The peripheral blood samples of the patients with epilepsy were collected. Drug compliance was confirmed in 20 per cent patient population using HPLC. Genotyping of CYP2C9 (FNx012 and FNx013), and CYP2C19 (FNx012 andFNx013) was carried out by PCR-RFLP. Results : The genotype frequencies of CYP2C9 430 C>T (FNx012 variant) and CYP2C9 1075 A>C (FNx013 variant) did not differ significantly in drug resistant versus responsive patients. After combining CYP2C9 FNx012 and CY... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5308656 Thu, 01 Sep 2011 04:00:00 +0100 5308656 http://www.medworm.com/index.php?rid=5308655&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21985812%26dopt%3DAbstract Authors: Gomber S, Arora SK, Das S, Ramachandran VG Abstract Background & objectives : MMR vaccine in a two dose schedule has successfully eliminated measles, mumps and rubella from many developed countries. In India, it is not a part of national immunization programme but is included in the State immunization programme of Delhi as a single dose between 15-18 months. This prospective study was carried out to assess the extent of seroprotection against these three diseases in immunized children and to study the immune response to a second dose of MMR. Methods : Consecutive children aged 4-6 yr, attending the immunization clinic of a tertiary care hospital in Delhi for routine DT vaccination, were enrolled. Second dose of MMR was given and pre- and post-vaccination antibody level... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5308655 Thu, 01 Sep 2011 04:00:00 +0100 5308655 http://www.medworm.com/index.php?rid=5308654&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21985813%26dopt%3DAbstract This study was designed to evaluate the impact of sports training on dietary intake and bone mineral and metabolic parameters in young healthy Indian females. Methods: Healthy female college going students (N=186, sportswomen, 90; controls 96) in the age group of 18-21 yr, residing in New Delhi (India) were evaluated for anthropometry, biochemistry (serum total and ionic calcium, phosphorus, total alkaline phosphatase, 25-hydroxyvitamin D & parathyroid hormone), diet, physical activity and lifestyle. Bone mineral density (BMD) at hip, forearm and lumbar spine were studied using central DXA. Results: Sports related physical activity (3 vs. 0 h/day, P<0.001) and direct sunlight exposure (120 vs. 30 min/day, P<0.001) were significantly higher in sportswomen than in controls with sed... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5308654 Thu, 01 Sep 2011 04:00:00 +0100 5308654 http://www.medworm.com/index.php?rid=5308653&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21985814%26dopt%3DAbstract Authors: Walia R, Bhansali A, Dutta P, Khandelwal N, Sialy R, Bhadada S Abstract Background & objectives : Hyperprolactinaemia affects testicular functions by influencing hypothalamo-pituitary-testicular (HPT) axis at various levels. Available literature on the level of defect, time course of improvement of gonadal functions and its relation with decline in prolactin levels is scanty. We carried out this study to evaluate the HPT axis in patients with macroprolactinomas, before and six months after cabergoline therapy. Methods: Fifteen men with macroprolactinomas underwent gonadotropin and testosterone response to their respective stimuli before and after six months of cabergoline therapy. Results: Serum prolactin levels decreased after six months of therapy. Pretreatment, mean... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5308653 Thu, 01 Sep 2011 04:00:00 +0100 5308653 http://www.medworm.com/index.php?rid=5308652&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21985815%26dopt%3DAbstract Authors: Harishankar N, Vajreswari A, Giridharan NV Abstract Background & objectives : WNIN/GR-Ob is a mutant obese rat strain with impaired glucose tolerance (IGT) developed at the National Institute of Nutrition (NIN), Hyderabad, India, from the existing 80 year old Wistar rat (WNIN) stock colony. The data presented here pertain to its obese nature along with IGT trait as evidenced by physical, physiological and biochemical parameters. The study also explains its existence, in three phenotypes: homozygous lean (+/+), heterozygous carrier (+/-) and homozygous obese (-/-). Methods: Thirty animals (15 males and 15 females) from each phenotype (+/+, +/-, -/-) and 24 lean and obese (6 males and 6 females) rats were taken for growth and food intake studies respectively. Twelve adul... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5308652 Thu, 01 Sep 2011 04:00:00 +0100 5308652 http://www.medworm.com/index.php?rid=5308651&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21985816%26dopt%3DAbstract We present here haematology, histology and pathophysiological changes between the phenotypes of these strains, lean (+/+), carrier (+/-) and obese (-/-). Methods: A total of 72 animals of equal gender consisting of three phenotypes were used for the study. Haematology, organ weights were measured and histopathology of the tissues studied using standard procedures. In 12 lean and obese rats (equal gender) of WNIN/GR-Ob group morphometry of pancreatic islets was done immunohistochemically (IHC). Results: Obese rats of both the strains showed normal haematology (except low platelet count), but exhibited changes in the organ weights and in histopathology in organs like liver, kidney, brain and testis/ovary. Hyperplasia of adipocytes was seen in obese rats as compared to lean and carrier. IHC o... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5308651 Thu, 01 Sep 2011 04:00:00 +0100 5308651 http://www.medworm.com/index.php?rid=5308650&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21985817%26dopt%3DAbstract Authors: Mattoo SK, Chakraborty K, Basu D, Ghosh A, Vijaya Kumar KG, Kulhara P Abstract Background & objectives : The research on the association of metabolic syndrome (MS) and substance abuse is scanty. The present research aimed to study the prevalence and correlates of MS among the inpatients at a Drug De-addiction Centre in north India. Methods: Consecutive male subjects (N=110) admitted to a drug de-addiction centre during July to December 2009 with a primary diagnosis of alcohol or opioid dependence were evaluated for the presence of MS as per the International Diabetes Federation (IDF) criteria. Results: The prevalence of MS was 24.6 and 29.3 per cent in alcohol and opioid dependent groups, respectively. MS showed a significant association with the age and body mass inde... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5308650 Thu, 01 Sep 2011 04:00:00 +0100 5308650 http://www.medworm.com/index.php?rid=5308649&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21985818%26dopt%3DAbstract This study was aimed to document the knowledge and practices in kala-azar case management of public and private health providers in these three countries. Methods: A health care provider survey was conducted in 2007 at 4 study sites, viz., Muzaffarpur and Vaishali districts in India, Mahottari district in Nepal, and Rajshahi district in Bangladesh. Interviews were conducted with formal and informal health care providers at their home or practice. Results: About half of the providers in India and Nepal knew the rapid diagnostic test rK39 recommended by the elimination initiative, but this was not in Bangladesh. Knowledge of the recommended first-line drug, miltefosine, was good in India and Nepal but less so in Bangladesh. Interpretation & conclusions : Innovative tools for VL care have... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5308649 Thu, 01 Sep 2011 04:00:00 +0100 5308649 http://www.medworm.com/index.php?rid=5308648&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21985819%26dopt%3DAbstract Authors: Xi X, Han X, Li L, Zhao Z Abstract Background & objectives : The unique immunological functions of γδ T lymphocytes to contribute immunity against Mycobacterium tuberculosis0 attracted interest of researchers. However, little is known about the specificity of γδ Τ cell in tuberculosis patients and the lack of exact tuberculosis antigen recognized by γδ T cells limited its application. The analysis of complementary determinant region (CDR)3 sequence characteristic in γδ T cells of tuberculosis patients would contribute to understand the distribution specificity of γδ T cell. In present study, we investigated the diversity of the γ9/δ2 T cell immunorepertoire and analysed the specificity of the expressed CDR3 in pulmonary tuberculosis patients. Methods: The ... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5308648 Thu, 01 Sep 2011 04:00:00 +0100 5308648 http://www.medworm.com/index.php?rid=5308647&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21985820%26dopt%3DAbstract Authors: Guo JH, Xiang WL, Zhang G, Luo T, Xie N, Yang ZR, Sun Q Abstract Background & objectives : Emergence and spread of drug resistant Mycobacterium tuberculosis is a serious threat to tuberculosis (TB) control programme. Therefore, the objective of this study was to genotype drug-resistant M. tuberculosis strains isolated from patients in Sichuan, China, using Mycobacterial Interspersed Repetitive Units (MIRU) for epidemiological analysis. Methods: Drug-resistance testing of M. tuberculosis isolates from pulmonary TB patients was confirmed by proportion method. Twelve MIRU loci were analyzed on 80 drug-resistant and 9 susceptible isolates by polymerase chain reaction and agarose gel electrophoresis. Hunter-Gaston discriminatory index (HGI) values were determined for each 1... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5308647 Thu, 01 Sep 2011 04:00:00 +0100 5308647 http://www.medworm.com/index.php?rid=5308646&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21985821%26dopt%3DAbstract Authors: Jisha S, Sreeja S, Manjula S Abstract Background & objectives: The mature fruits of Solanum nigrum contains steroidal glycosides. These are often used as vegetable and there are evidences on tribal use of these fruits as an oral contraceptive. The present study was carried out to evaluate the estrogenic potential of S. nigrum fruits by in vitro and in vivo assays. Methods: Defatted methanol extract of dried S. nigrum fruits was column fractionated and the glycoside positive fractions pooled. Definite concentrations of the fraction were used for in vitro and in vivo assays. The effect on cell viability was analyzed in MCF-7 cell lines by MTT assay followed by in vitro evaluation of estrogenicity by hydroxy apatite (HAP) binding assay. The results were further evaluated ... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5308646 Thu, 01 Sep 2011 04:00:00 +0100 5308646 http://www.medworm.com/index.php?rid=5308645&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21985822%26dopt%3DAbstract Authors: Elango G, Zahir AA, Bagavan A, Kamaraj C, Rajakumar G, Santhoshkumar T, Marimuthu S, Rahuman AA Abstract Background & objectives : Mosquito control is facing a threat due to the emergence of resistance to synthetic insecticides. Insecticides of plant origin may serve as suitable alternative biocontrol techniques in the future. The purpose of the present study was to assess the ethyl acetate, acetone and methanol extracts of Andrographis paniculata, Eclipta prostrata and Tagetes erecta leaves tested for oviposition-deterrent, ovicidal and repellent activities against malaria vector, Anopheles subpictus Grassi (Diptera: Culicidae). Methods: The dried leaves of the three plants were powdered mechanically and extracted with ethyl acetate, acetone and methanol. One gram of ... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5308645 Thu, 01 Sep 2011 04:00:00 +0100 5308645 http://www.medworm.com/index.php?rid=5308644&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21985823%26dopt%3DAbstract Authors: Singh S, Nair V, Gupta YK Abstract Background & objectives: Majoon Suranjan (MS) is a polyherbal formulation used in Unani system of medicine for the treatment of rheumatoid arthritis (RA). The present study evaluates the antiarthritic efficacy of this formulation in three different experimental models. Methods: The anti-inflammatory activity of MS (in doses of 450, 900 and 1800 mg/kg body wt) was evaluated using the turpentine oil induced paw oedema model and the antiarthritic efficacy was evaluated using the formaldehyde and complete Freund's adjuvant (CFA) induced arthritis models. Aspirin (100 mg/kg body wt) was used as the standard drug in all the models. In order to assess the safety of the test drug, oral acute and 28 day toxicity studies were also carried out. ... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5308644 Thu, 01 Sep 2011 04:00:00 +0100 5308644 http://www.medworm.com/index.php?rid=5308643&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21985824%26dopt%3DAbstract Authors: Indavarapu A, Akinapelli A Abstract Background & objectives: During an outbreak of influenza like illness throat swab culture and virus isolation are done to identify causal virus, and it may cause a significant delay in diagnosis and isolation. There is a need to determine a sensitive laboratory parameter which could play a major role in identifying H1N1 infection among patients presenting with influenza like symptoms. We undertook this study to determine a laboratory parameter to identify swine influenza infection amoung patients presenting with influenza like symptoms while awaiting throat swab culture and virus isolation reports. Methods: This retrospective study was conducted on patients presenting to A.P TB and Chest Hospital, Hyderabad, with swine influenza symp... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5308643 Thu, 01 Sep 2011 04:00:00 +0100 5308643 http://www.medworm.com/index.php?rid=5308642&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21985825%26dopt%3DAbstract Authors: Parveen RM, Khan MA, Menezes GA, Harish BN, Parija SC, Hays JP PMID: 21985825 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5308642 Thu, 01 Sep 2011 04:00:00 +0100 5308642 http://www.medworm.com/index.php?rid=5308641&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21985826%26dopt%3DAbstract Authors: Venkatesh S, Shamsi MB, Deka D, Saxena V, Kumar R, Dada R PMID: 21985826 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5308641 Thu, 01 Sep 2011 04:00:00 +0100 5308641 http://www.medworm.com/index.php?rid=5308640&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21985827%26dopt%3DAbstract Authors: Chitambar SD, Lahon A, Tatte VS, Maniya NH, Tambe GU, Khatri KI, Desai HS, Ugare MR, Kulkarni SV, Waghmare AP PMID: 21985827 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5308640 Thu, 01 Sep 2011 04:00:00 +0100 5308640 http://www.medworm.com/index.php?rid=5087843&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21808124%26dopt%3DAbstract Authors: Kar P PMID: 21808124 [PubMed - as supplied by publisher] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5087843 Thu, 30 Jun 2011 23:00:00 +0100 5087843 http://www.medworm.com/index.php?rid=5087842&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21808125%26dopt%3DAbstract Authors: Math SB PMID: 21808125 [PubMed - as supplied by publisher] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5087842 Thu, 30 Jun 2011 23:00:00 +0100 5087842 http://www.medworm.com/index.php?rid=5087841&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21808126%26dopt%3DAbstract Authors: Prabhakaran D, Singh K PMID: 21808126 [PubMed - as supplied by publisher] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5087841 Thu, 30 Jun 2011 23:00:00 +0100 5087841 http://www.medworm.com/index.php?rid=5087840&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21808127%26dopt%3DAbstract Authors: Chaudhry R PMID: 21808127 [PubMed - as supplied by publisher] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5087840 Thu, 30 Jun 2011 23:00:00 +0100 5087840 http://www.medworm.com/index.php?rid=5087839&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21808128%26dopt%3DAbstract Authors: Bose M PMID: 21808128 [PubMed - as supplied by publisher] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5087839 Thu, 30 Jun 2011 23:00:00 +0100 5087839 http://www.medworm.com/index.php?rid=5087838&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21808129%26dopt%3DAbstract Authors: Prandoni P, Piovella C, Spiezia L, Valle FD, Pesavento R The risk of recurrent venous thromboembolism (VTE) approaches 40 per cent of all patients after 10 yr of follow up. This risk is higher in patients with permanent risk factors of thrombosis such as active cancer, prolonged immobilization from medical diseases, and antiphospholipid syndrome; in carriers of several thrombophilic abnormalities, including deficiencies of natural anticoagulants; and in patients with unprovoked presentation. Patients with permanent risk factors of thrombosis should receive indefinite anticoagulation, consisting of subtherapeutic doses of low molecular weight heparin in cancer patients, and oral anticoagulants in all other conditions. Patients whose VTE is triggered by major surgery or trauma s... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5087838 Thu, 30 Jun 2011 23:00:00 +0100 5087838 http://www.medworm.com/index.php?rid=5087837&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21808130%26dopt%3DAbstract Authors: Ganguly NK, Bhattacharya SK, Sesikeran B, Nair GB, Ramakrishna BS, Sachdev HP, Batish VK, Kanagasabapathy AS, Muthuswamy V, Kathuria SC, Katoch VM, Satyanarayana K, Toteja GS, Rahi M, Rao S, Bhan MK, Kapur R, Hemalatha R There has been an increased influx of probiotic products in the Indian market during the last decade. However, there has been no systematic approach for evaluation of probiotics in food to ensure their safety and efficacy. An initiative was, therefore, taken by the Indian Council of Medical Research (ICMR) along with the Department of Biotechnology (DBT) to formulate guidelines for regulation of probiotic products in the country. These guidelines define a set of parameters required for a product/strain to be termed as 'probiotic'. These include identification ... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5087837 Thu, 30 Jun 2011 23:00:00 +0100 5087837 http://www.medworm.com/index.php?rid=5087836&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21808131%26dopt%3DAbstract Authors: Panwar RB, Gupta R, Gupta BK, Raja S, Vaishnav J, Khatri M, Agrawal A Background & objectives : It was hypothesized that both thrombogenic and atherogenic factors may be responsible for premature coronary heart disease (CHD) in young Indians. A case-control study was performed to determine cardiovascular risk factors in young patients with CHD in India. Methods: Successive consenting patients <55 yr with an acute coronary event or recent diagnosis of CHD were enrolled (cases, n=165). Age- and gender-matched subjects with no clinical evidence of CHD were recruited as controls (n=199). Demographic, anthropometric, clinical, haematological, and biochemical data were obtained in both groups. Univariate and multivariate logistic regression were performed to identify importan... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5087836 Thu, 30 Jun 2011 23:00:00 +0100 5087836 http://www.medworm.com/index.php?rid=5087835&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21808132%26dopt%3DAbstract Authors: Jain S, Ponmariappan S, Kumar O Background & objectives : Botulinum neurotoxins (A-G) are among most poisonous substances in the world, produced by obligate anaerobic bacteria Clostridum botulinum. Among the seven serotypes A, B, E and F are of human importance. In India, the prevalence of C. botulinum as well as botulism outbreaks have been reported. Due to its extreme toxicity it has been classified in the Category A of biological warfare agent. So far, there is no commercial detection system available in India to detect botulism. The present study aims to develop an immuno detection system for botulinum neurotoxin serotype B using synthetic gene approach. Methods: The truncated fragment of the botulinum neurotoxin type B from amino acid 1-450 was synthesized using PCR o... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5087835 Thu, 30 Jun 2011 23:00:00 +0100 5087835 http://www.medworm.com/index.php?rid=5087834&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21808133%26dopt%3DAbstract This study included 72 infertile women who met the inclusion and exclusion criteria. After a detailed history and clinical examination all patients were subjected to investigations including pelvic sonogram, HSG and laparoscopy. Endometrial samples from were allocated for AFB smear, culture and HPE examination. Only 49 samples were available for PCR using IS 6110 and TRC 4 primers. In seven patients peritoneal fluid was also taken for culture and PCR. Based on the clinical profile and laparoscopic findings, a diagnostic criteria was derived to suspect GTB. Specific diagnostic tests were evaluated against this diagnostic criterion. Results: Laparoscopy was suggestive of tuberculosis in 59.7 per cent of cases, AFB smear was positive in 8.3 per cent, culture was positive in 5.6 per cent, HPE ... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5087834 Thu, 30 Jun 2011 23:00:00 +0100 5087834 http://www.medworm.com/index.php?rid=5087833&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21808134%26dopt%3DAbstract This study attempts to compare the pattern of growth of Indian children as assessed by weight for age, height for age and BMI for age with the WHO standards for growth (2006) and to explore the implications of differences in undernutrition rates in the 0-59 months of age group as assessed by these three indices. Methods: From the National Family Health Survey -3 database, growth curves for height, weight and BMI for age in Indian preschool children were computed using LMS software and compared with the WHO (2006) standards. Using the WHO (2006) standards, trends in prevalence of undernutrition as assessed by height, weight and BMI for age in the 0-59 month age group were computed. Results: During the first three months there was no increase in underweight and stunting rates. There was prog... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5087833 Thu, 30 Jun 2011 23:00:00 +0100 5087833 http://www.medworm.com/index.php?rid=5087832&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21808135%26dopt%3DAbstract Authors: Das SN, Khare P, Singh MK, Sharma SC Background & objectives : Fas receptor and Fas Ligand (FasL) system has been implicated in the resistance to apoptosis, insensitivity to chemotherapy and in providing immune privileged status to most of the tumours. However, no reports are available on Fas and FasL expression in patients with tobacco-related oral carcinoma. Therefore, the present study was undertaken to observe Fas and FasL expression and their correlation with clinicopathological features as well as cell cycle parameters. Methods: Immunohistochemistry for Fas, FasL and DNA flow cytometry for cell cycle parameters was successfully done on 41 paraffin embedded tumour and 10 normal samples. The results were evaluated for possible association of Fas and FasL with clinicopa... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5087832 Thu, 30 Jun 2011 23:00:00 +0100 5087832 http://www.medworm.com/index.php?rid=5087831&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21808136%26dopt%3DAbstract Authors: Augustine LF, Vazir S, Rao SF, Vishnu Vardhana Rao M, Laxmaiah A, Nair KM Background & objectives : Psychosocial stressors leading to allostatic load need to be explored further as these have great scope for early intervention. Stress studies done in India are mostly based on sources of stress and objective measures of stress. Therefore, the objective of the present study was to assess stress appraisal among students (16-17 yr) and to identify institution-specific differences (Private vs. Government) in stress appraisal and coping. Methods: The study was carried out among 16-17 yr old apparently normal students. Eighty students were recruited from six schools ensuring equal representation from gender/category of schools (Government/ Private). Validated and culturally adapt... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5087831 Thu, 30 Jun 2011 23:00:00 +0100 5087831 http://www.medworm.com/index.php?rid=5087830&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21808137%26dopt%3DAbstract Authors: Mühl D, Woth G, Drenkovics L, Varga A, Ghosh S, Csontos C, Bogár L, Wéber G, Lantos J Background & objectives : We evaluated pro- and anti-oxidant disturbances in sepsis and non-sepsis burn patients with systemic inflammatory response syndrome (SIRS). Adhesion molecules and inflammation markers on leukocytes were also analyzed. We hypothesized that oxidative stress and leukocyte activation markers can lead to the severity of sepsis. Methods: In 28 severe sepsis and 27 acute burn injury patients blood samples were collected at admission and 4 days consecutively. Oxidative stress markers: production of reactive oxygen species (ROS), myeloperoxidase, malondialdehyde and endogenous antioxidants: plasma protein sulphydryl groups, reduced glutathione, superoxide dismutase and... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5087830 Thu, 30 Jun 2011 23:00:00 +0100 5087830 http://www.medworm.com/index.php?rid=5087829&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21808138%26dopt%3DAbstract In this study, we have done Pi (Protease inhibitor) phenotyping to investigate the possibility of association of any heterozygous (or homozygous) α1-AT deficiency in patients with TPE. Methods: Serum a1antitrypsin (α1-AT) was measured in 103 patients (Group A) with TPE, 99 patients with pulmonary eosinophilia who had associated intestinal worm infestation (Group B) and 43 healthy volunteers who served as controls. In 19 α1-AT deficient patients (9 of Group A and 10 of Group B), α1-AT level was measured before and after treatment. In 58 patients with TPE and in 5 controls, phenotyping was done. Results : Fifteen patients of Group A and 16 from Group B showed intermediate α1-AT deficiency (150 mg % or less. None of the control subjects had α1-AT deficiency (<200 mg%). After treatmen... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5087829 Thu, 30 Jun 2011 23:00:00 +0100 5087829 http://www.medworm.com/index.php?rid=5087828&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21808139%26dopt%3DAbstract This study was aimed to evaluate the serum total antioxidant capacity (TAC) as a single parameter in Eales' disease (ED) and in an acute inflammatory condition such as uveitis and in cataract which is chronic, compared to healthy controls. Methods: The TAC assay was done spectrophotometrically in the serum of Eales' disease cases (n=20) as well as in other ocular pathologies involving oxidative stress namely, uveitis and cataract (n=20 each). The oxidative stress measured in terms of TBARS, was correlated with the TAC. Individual antioxidants namely vitamin C, E and glutathione were also estimated and correlated with TAC. Results: TAC was found to be significantly lower in Eales' disease with active vasculitis (0.28 ± 0.09 mM, P<0.001), Eales' disease with healed vasculitis (0.67 ± 0.... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5087828 Thu, 30 Jun 2011 23:00:00 +0100 5087828 http://www.medworm.com/index.php?rid=5087827&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21808140%26dopt%3DAbstract This study was planned to estimate the prevalence of chronic cough and phlegm in the absence of dyspneoa and wheezing and to study its associated factors in a representative population of Mysore district. Methods: A cross-sectional survey was planned in a representative population of Mysore taluk. Eight villages were randomly selected based on the list of villages from census 2001. Trained field workers using the Burden of Obstructive Diseases questionnaire carried out a house-to-house survey. Results: A total of 4333 adult subjects were enrolled in the study with 2333 males and 2000 females. The prevalence of chronic cough in the community was 2.5 per cent and that of chronic phlegm was 1.2 per cent. A significant association was observed between chronic cough and age, gender, occupation ... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5087827 Thu, 30 Jun 2011 23:00:00 +0100 5087827 http://www.medworm.com/index.php?rid=5087826&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21808141%26dopt%3DAbstract Conclusions: Our data suggest that the bark ethyl acetate and methanol extract of A. squamosa, leaf ethyl acetate and methanol extract of C. indicum, acetone and ethyl acetate extract of T. procumbens have the potential to be used as an ecofriendly approach for the control of the An. subpictus, and Cx. tritaeniorhynchus. PMID: 21808141 [PubMed - as supplied by publisher] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5087826 Thu, 30 Jun 2011 23:00:00 +0100 5087826 http://www.medworm.com/index.php?rid=5087825&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21808142%26dopt%3DAbstract Authors: Gautam S, Agrawal CG, Bid HK, Banerjee M Background & objectives: The greater tendency to diabetes in Indians may be due to genetic factors in addition to environment and diet. CD36, a class B scavenger cell surface receptor mediates internalization of oxidized low density lipoprotein (Ox-LDL) leading to the formation of macrophage foam cells. CD36 deficiency is related to phenotypic expression of the metabolic syndrome, frequently associated with atherosclerotic cardiovascular diseases resulting in raised levels of glucose thereby contributing to type 2 diabetes (T2DM). Therefore, the association of human CD36 gene mutation to T2DM needs investigation. We undertook this study to investigate CD36 gene status in north Indian subjects by screening for the deletion of exons 3... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5087825 Thu, 30 Jun 2011 23:00:00 +0100 5087825 http://www.medworm.com/index.php?rid=5087824&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21808143%26dopt%3DAbstract Authors: Thakur L, Ray K, Anand JP, Panjwani U Background & objectives: The P300 wave is an event related potential (ERP) elicited by infrequent, task-relevant stimuli and appeared at about 300 ms, represents higher cognitive function of information processing, working memory or stimulus categorization. Hypobaric hypoxia deteriorates the cognitive function during the short term stay (days to few weeks) at high altitude. The present study was carried out to evaluate the P300 responses during long duration stay (1 month and 6 months) at high altitude (HA, 4115 m) in a sample of Indian lowlanders. Methods: The study was carried out on 18 healthy male volunteers at sea level (SL). The volunteers were stage inducted to 4115 m altitude in the Eastern Himalayas. The P300 was recorded afte... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5087824 Thu, 30 Jun 2011 23:00:00 +0100 5087824 http://www.medworm.com/index.php?rid=5087823&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21808144%26dopt%3DAbstract Authors: Agarwal SM, Agrawal A Background & objectives: Hyponatremia is a common problem encountered in patients presenting with nonspecific symptoms. We undertook this study to investigate the clinical profile of patients with hyponatremia, the precipitating factors, the response to therapy and to compare, using these parameters, hyponatremia at presentation to that developing in the hospital. Methods: Seventy consecutive patients with serum sodium less than or equal to 125 mmol/l at presentation or at any time during hospital admission were identified and studied using a proforma. The severity of hyponatremia, therapy given and time taken for recovery were analysed. Results: The mean age of patients was 48.1 ± 16.1 yr. The mean serum sodium was 117.8 ± 6.4 mmol/l. Confusion, he... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5087823 Thu, 30 Jun 2011 23:00:00 +0100 5087823 http://www.medworm.com/index.php?rid=5087822&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21808145%26dopt%3DAbstract Authors: Arya SC, Agarwal N PMID: 21808145 [PubMed - as supplied by publisher] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5087822 Thu, 30 Jun 2011 23:00:00 +0100 5087822 http://www.medworm.com/index.php?rid=5087821&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21808146%26dopt%3DAbstract Authors: Nambiar D PMID: 21808146 [PubMed - as supplied by publisher] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5087821 Thu, 30 Jun 2011 23:00:00 +0100 5087821 http://www.medworm.com/index.php?rid=5087820&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21808147%26dopt%3DAbstract Authors: Math SB, Nirmala MC PMID: 21808147 [PubMed - as supplied by publisher] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5087820 Thu, 30 Jun 2011 23:00:00 +0100 5087820 http://www.medworm.com/index.php?rid=5087819&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D21808148%26dopt%3DAbstract Authors: Bajpai V PMID: 21808148 [PubMed - as supplied by publisher] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=5087819 Thu, 30 Jun 2011 23:00:00 +0100 5087819 http://www.medworm.com/index.php?rid=3981351&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20847366%26dopt%3DAbstract Authors: Sinha N, Saran RK PMID: 20847366 [PubMed - as supplied by publisher] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3981351 Tue, 31 Aug 2010 23:00:00 +0100 3981351 http://www.medworm.com/index.php?rid=3981350&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20847367%26dopt%3DAbstract Authors: Mehendale S PMID: 20847367 [PubMed - as supplied by publisher] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3981350 Tue, 31 Aug 2010 23:00:00 +0100 3981350 http://www.medworm.com/index.php?rid=3981349&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20847368%26dopt%3DAbstract Authors: Maharaj R PMID: 20847368 [PubMed - as supplied by publisher] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3981349 Tue, 31 Aug 2010 23:00:00 +0100 3981349 http://www.medworm.com/index.php?rid=3981348&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20847369%26dopt%3DAbstract Authors: Ray JG, Berger H, Lipscombe LL, Sermer M Women with gestational diabetes mellitus (GDM) have higher rates of foetal macrosomia, shoulder dystocia and pregnancy-induced hypertension, and are at higher risk of developing type 2 diabetes. Herein, we introduce a new conceptual term, "gestational prediabetes", which requires the absence of diabetes before pregnancy, and the presence of blood glucose levels (or a related marker) in early pregnancy that are higher than normal, but not yet high enough to meet the diagnostic criteria for GDM. Identifying women with gestational prediabetes might be done in early pregnancy (e.g., 12 weeks' gestation) using conventional glycaemic testing, assessment of visceral abdominal adiposity or hepatic fat by ultrasonography, or measuring serum sex ... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3981348 Tue, 31 Aug 2010 23:00:00 +0100 3981348 http://www.medworm.com/index.php?rid=3981347&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20847370%26dopt%3DAbstract In this study HIV prevalence estimates obtained from PPTCT programme and HSS were compared to find out the utility of PPTCT programme data for HIV surveillance. Methods: The data of HSS and PPTCT programme were obtained from National AIDS Control Organization, New Delhi. A list of PPTCT programme sites where ANC HSS was also conducted during 2005 to 2007 was prepared. HIV prevalence and 95 per cent confidence interval (CI) were estimated from antenatal attendees in PPTCT and HSS. Correlation coefficient of HIV prevalence in PPTCT and HSS was also examined according to the level of HIV test acceptance in PPTCT programme. Pregnant women presenting directly for labour in PPTCT centers were not included in the analyses. Results: In 2007, HIV test acceptance ranged from 8 to 100 per cent (avera... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3981347 Tue, 31 Aug 2010 23:00:00 +0100 3981347 http://www.medworm.com/index.php?rid=3981346&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20847371%26dopt%3DAbstract This study was undertaken in these areas to study the persistence of resistance to DDT, malathion and deltamethrin after sequential withdrawal of IRS with these insecticides at different times. Methods: Susceptibility tests on An. culicifacies were conducted using standard WHO methods and kits. Mortality, knockdown time and lethal times were calculated for An. culicifacies exposed to WHO prescribed diagnostic concentrations of different insecticide impregnated papers. Results: Persistence of DDT-resistance was observed even after 30 yr of its withdrawal from IRS. Similarly, persistence of malathion resistance was also observed after 9 yr of its withdrawal from IRS, while reversal of deltamethrin-resistance was observed very fast within 2-3 yr after its withdrawal from IRS in 2002. Interpre... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3981346 Tue, 31 Aug 2010 23:00:00 +0100 3981346 http://www.medworm.com/index.php?rid=3981345&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20847372%26dopt%3DAbstract Authors: Mirfakhraie R, Mirzajani F, Kalantar SM, Montazeri M, Salsabili N, Pourmand GR, Houshmand M Background & objectives:Genetic factors contribute about 10 per cent of male infertility. Among these, genes in azoospermia factor (AZF) region including AZFa, AZFb, AZFc and AZFd on the long arm of Y chromosome are considered most important for spermatogenesis. Deletions in these regions are thought to be involved in some cases of male infertility associated with azoospermia or oligozoospermia. We studied the incidence of AZF deletions among Iranian infertile men with idiopathic non-obstructive azoospermia. Methods: A total of 100 Iranian azoospermic infertile men were selected for the molecular study of Y chromosome microdeletions. The presence of 13 sequence tagged site (STS) mar... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3981345 Tue, 31 Aug 2010 23:00:00 +0100 3981345 http://www.medworm.com/index.php?rid=3981344&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20847373%26dopt%3DAbstract This study was undertaken to assess the association of hypoadiponectinemia with NAFLD in Asian Indians. Method: In this cross-sectional study, subjects were randomly selected from Phase 5 of the Chennai Urban Rural Epidemiology Study (CURES), an epidemiological study based on a representative population of Chennai in south India. One hundred twenty one subjects without NAFLD and 72 subjects with NAFLD were selected. NAFLD was diagnosed by ultrasonography. Serum adiponectin levels were measured using radioimmunoassay. Insulin resistance was calculated using Homeostasis Assessment model (HOMA-IR). Results: Serum adiponectin values were significantly lower in subjects with NAFLD compared to those without [5.6 μg/ml (95% Confidence Interval (CI) 5.0 - 6.3 μg/ml] vs 7.4 μg/ml (95% CI: ... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3981344 Tue, 31 Aug 2010 23:00:00 +0100 3981344 http://www.medworm.com/index.php?rid=3981343&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20847374%26dopt%3DAbstract Authors: Sharma SK, Sinha S, Danishad KA, Sharma U, Sharma H, Mishra HK, Mishra H, Kadhiravan T, Reddy VV, Sreenivas V, Jagannathan NR Background & objectives: Repeated apnoeic/hypoapnoeic episodes during sleep may produce cerebral damage in patients with obstructive sleep apnoea (OSA). The aim of this study was to determine the absolute concentration of cerebral metabolites in apnoeic and non-apnoeic subjects from different regions of the brain to monitor the regional variation of cerebral metabolites. Methods: Absolute concentration of cerebral metabolites was determined by using early morning proton magnetic resonance spectroscopy ((1)H MRS) in 18 apnoeic patients with OSA (apnoeics) having apnoea/hypopnoea index (AHI) >5/h, while 32 were non-apnoeic subjects with AHI< 5/h... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3981343 Tue, 31 Aug 2010 23:00:00 +0100 3981343 http://www.medworm.com/index.php?rid=3981342&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20847375%26dopt%3DAbstract In this study we compared fluorescence in situ hybridization (FISH) and immunohistochemistry (IHC) for the determination of HER2 status in breast cancer patients referred to a tertiary care referral centre. Methods: A total of 200 cases of invasive breast cancer were evaluated for HER2 status using IHC and FISH and results were compared. Results: The IHC 3+ (93.9%) and IHC negative (85.9%) cases showed good concordance with the corresponding FISH results; while 66.6 per cent of IHC 2+ cases showed gene amplification by FISH. In addition, hormone receptor expression and HER2 gene status showed a statistically significant inverse association (P<0.05). Interpretation & conclusion: These findings reaffirm IHC as a prudent first-step to screen tissue samples for HER2 status and to determ... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3981342 Tue, 31 Aug 2010 23:00:00 +0100 3981342 http://www.medworm.com/index.php?rid=3981341&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20847376%26dopt%3DAbstract Authors: Yu M, Zheng HC, Xia P, Takahashi H, Masuda S, Takano Y, Xu HM Background & objectives: Gastric cancer is the fourth most common cancer and the second leading cause of cancer-related deaths after lung carcinoma. The aim of this study was to understand the difference in clinicopathological behaviours and prognosis of gastric cancer in patients from China and Japan. Methods: Paraffin-fixed tissue samples of gastric cancer were collected retrospectively from two hospitals between 1993 to 2006 in Japan (n=2063) and during 1980-2003 in China (n=2496) respectively, and staging was done by TNM system and typing by Japanese Endoscopy Society criteria or Borrmann's classification. The histological architecture of the tumours was expressed according to Lauren's classification. Result... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3981341 Tue, 31 Aug 2010 23:00:00 +0100 3981341 http://www.medworm.com/index.php?rid=3981340&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20847377%26dopt%3DAbstract In this study we evaluated the efficacy of using multiplex PCR (mPCR) of 30 exons followed by multiplex ligation-dependent probe amplification (MLPA), to study deletions and duplications in the DMD gene in patients clinically diagnosed as BMD/DMD. Methods: Using an algorithm of mPCR and MLPA which was less invasive and cost-effective, we performed retrospective and prospective analysis on 150 male patients. Results: Multiplex PCR could pick up deletions in 103 of the 150 cases. MLPA was able to detect deletions and duplications including nine additional mutations. Further, the borders of the deletions and duplications were more accurately defined by this recent methodology, which enables one to determine the effect of the mutation on the reading frame. In all, including the single exon del... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3981340 Tue, 31 Aug 2010 23:00:00 +0100 3981340 http://www.medworm.com/index.php?rid=3981339&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20847378%26dopt%3DAbstract This study was aimed to evaluate the presence of anti-HBc and to determine the presence or absence of HBV DNA in the serum samples from HBsAg negative, anti-HBc positive blood donors in a tertiary care hospital blood bank from Delhi. Methods: A total of 2175 HBsAg negative, first time volunteer blood donors were included in the study from blood bank, Lok Nayak Hospital, New Delhi. The blood specimens from all these subjects were evaluated for anti-HBV-core antigen (anti-HBc) serology, anti-HBV-surface antigen (anti-HBs) titres and HBeAg. The presence of HBV DNA was evaluated by testing, through polymerase chain reaction (PCR) techniques. Results: Of the 2175 HBsAg negative voluntary blood donors, 413 (19.8%) were tested to be positive for anti-HBc alone. Of these, 153 (group-I) were anti-H... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3981339 Tue, 31 Aug 2010 23:00:00 +0100 3981339 http://www.medworm.com/index.php?rid=3981338&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20847379%26dopt%3DAbstract Authors: Mojumdar K, Vajpayee M, Chauhan NK, Mendiratta S, Wig N Background & objectives: DCs trigger both innate and adaptive immune responses to control HIV infection and represent a viral reservoir acting as target and HIV carriers for infection of permissive CD4(+) T-cells. DCs thus form a very attractive study subject to further our existing knowledge of HIV induced immunopathogenesis due to its diverse and crucial role in HIV infection establishment, viral dissemination, immune evasion, viral persistence, etc. We aimed to characterize the effect of HIV infection on myeloid and plasmacytoid dendritic cell subsets in a group of HIV-1 subtype C infected treated or untreated Indian individuals. Methods: Blood DC subset numbers and immunophenotype were studied for 79 HIV infected ... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3981338 Tue, 31 Aug 2010 23:00:00 +0100 3981338 http://www.medworm.com/index.php?rid=3981337&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20847380%26dopt%3DAbstract Authors: Bonyadian M, Momtaz H, Rahimi E, Habibian R, Yazdani A, Zamani M Background & objectives: Verotoxigenic Escherichia coli are important serotypes of enterohaemorrhagic E. coli (EHEC) subgroup that cause attaching and effacing lesions in enterocytes by producing verotoxins or shiga-like toxins resulting in haemorrhagic colitis (HC) and haemolytic uremic syndrome (HUS). The aim of this study was to detect these serotypes specially E. coli O157:H7 in stool samples of patients with diarrhoea and identification of virulence genes (STX1, STX2, Hly and EAE) in Shahrekord-Iran area using PCR technique. Methods: Two hundred diarrhoeal stool samples of patients were collected through 2007-2008. Microbiological and biochemical examinations were done to detect the E. coli. Serological ... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3981337 Tue, 31 Aug 2010 23:00:00 +0100 3981337 http://www.medworm.com/index.php?rid=3981336&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20847381%26dopt%3DAbstract This study was undertaken to characterize ESBL producers among Escherichia coli and Klebsiella pneumoniae by PCR-RFLP, which were initially screened by phenotypic method. Methods: A total of 100 isolates of each species (E. coli and K. pneumoniae) were screened for ESBL production. PCR analysis for β-lactamase genes of the family TEM and SHV was also carried out. PCR products of TEM and SHV genes were subjected to digest with three different restriction enzymes. The digested products were run on 1.5 per cent agarose gel, stained and examined for DNA bands. Results: PCR carried out on plasmid DNA alone detected 30 per cent ESBL positive isolates using TEM primer and 38 per cent using SHV primer, whereas PCR for both plasmid and chromosomal DNA showed 56 per cent positivity for TEM and 60... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3981336 Tue, 31 Aug 2010 23:00:00 +0100 3981336 http://www.medworm.com/index.php?rid=3981335&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20847382%26dopt%3DAbstract Authors: Bhattacharya SK, Rinzin N, Chusak P, Dash AP, Chowdhury R, Tobgay T, Narain JP PMID: 20847382 [PubMed - as supplied by publisher] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3981335 Tue, 31 Aug 2010 23:00:00 +0100 3981335 http://www.medworm.com/index.php?rid=3981334&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20847383%26dopt%3DAbstract Authors: Paramasivan R, Dhananjeyan KJ, Leo SV, Muniaraj M, Thenmozhi V, Rajendran R, Tewari SC, Arunachalam N, Varatharaj M, Victor TJ, Charles J, Ilango S, Tyagi BK PMID: 20847383 [PubMed - as supplied by publisher] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3981334 Tue, 31 Aug 2010 23:00:00 +0100 3981334 http://www.medworm.com/index.php?rid=3981333&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20847384%26dopt%3DAbstract Authors: Singh SM PMID: 20847384 [PubMed - as supplied by publisher] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3981333 Tue, 31 Aug 2010 23:00:00 +0100 3981333 http://www.medworm.com/index.php?rid=3881873&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20716810%26dopt%3DAbstract Authors: Satyanarayana K, Sharma A PMID: 20716810 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3881873 Sat, 31 Jul 2010 23:00:00 +0100 3881873 http://www.medworm.com/index.php?rid=3881872&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20716811%26dopt%3DAbstract Authors: Say L PMID: 20716811 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3881872 Sat, 31 Jul 2010 23:00:00 +0100 3881872 http://www.medworm.com/index.php?rid=3881871&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20716812%26dopt%3DAbstract Authors: Jacob John T PMID: 20716812 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3881871 Sat, 31 Jul 2010 23:00:00 +0100 3881871 http://www.medworm.com/index.php?rid=3881870&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20716813%26dopt%3DAbstract Authors: Bhatt AN, Mathur R, Farooque A, Verma A, Dwarakanath BS In the recent years, knowledge about cancer biomarkers has increased tremendously providing great opportunities for improving the management of cancer patients by enhancing the efficiency of detection and efficacy of treatment. Recent technological advancement has enabled the examination of many potential biomarkers and renewed interest in developing new biomarkers. Biomarkers of cancer could include a broad range of biochemical entities, such as nucleic acids, proteins, sugars, lipids, and small metabolites, cytogenetic and cytokinetic parameters as well as whole tumour cells found in the body fluid. A comprehensive understanding of the relevance of each biomarker will be very important not only for diagnosing the diseas... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3881870 Sat, 31 Jul 2010 23:00:00 +0100 3881870 http://www.medworm.com/index.php?rid=3881869&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20716814%26dopt%3DAbstract Authors: Kulkarni R, Chauhan S, Shah B, Menon G Background & objectives: Reliable data on mortality and morbidity among women of reproductive age group are scarce in India. The present study is the Maharashtra component of a large multicentric task force study on the cause of death by verbal autopsy conducted in five States of India. The data pertaining to deaths among reproductive age group women are presented along with the factors contributing to these deaths. Methods: House-to-house surveys of a representative population from rural and urban areas in six districts of Maharashtra were undertaken by probability of proportion to size (PPS) sampling. Information on death was obtained from the relatives of the deceased and cause of death was assigned using the standardized algorithm... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3881869 Sat, 31 Jul 2010 23:00:00 +0100 3881869 http://www.medworm.com/index.php?rid=3881868&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20716815%26dopt%3DAbstract Authors: Jadi RS, Sudeep AB, Kumar S, Arankalle VA, Mishra AC Background & objectives: Since not much information on Chandipura virus is available, an attempt was made to study the growth kinetics of the virus in certain vertebrate, invertebrate cell lines and embryonated chicken eggs. Methods: Comparative study of Chandipura virus (CHPV) growth kinetics in three vertebrate cell lines [Vero E6, Rhabdo myosarcoma (RD), Porcine stable kidney (PS) cell lines], two insect cell lines [Aedes aegypti (AA) and Phlebotomus papatasi (PP-9) cell lines] and embryonated pathogen free chicken eggs was conducted, by tissue culture infective dose 50 per cent (TCID(50)) and indirect immunofluorescence assay (IFA). Results: All the cell lines and embryonated egg supported the growth of CHPV and yiel... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3881868 Sat, 31 Jul 2010 23:00:00 +0100 3881868 http://www.medworm.com/index.php?rid=3881867&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20716816%26dopt%3DAbstract Authors: Nagarajan K, Saikumar G, Arya RS, Gupta A, Somvanshi R, Pattnaik B Background & objectives:With the emergence of a new reassortant influenza A H1N1 virus that caused the 2009 pandemic it was felt necessary that pigs should be closely monitored for early detection of any influenza virus infection. Therefore, we investigated disease outbreaks with clinical history suggestive for swine influenza reported to our laboratory by owners of affected pig farms in Uttar Pradesh. Methods: Detection of swine influenza A virus (SIV) was attempted by isolation in embryonated chicken eggs. Presence of virus was detected by haemagglutination (HA) test and RT-PCR for amplification of different gene segments, cloning and sequencing. BLAST analysis of sequence data, phylogenetic analysis and ... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3881867 Sat, 31 Jul 2010 23:00:00 +0100 3881867 http://www.medworm.com/index.php?rid=3881866&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20716817%26dopt%3DAbstract Authors: Mehendale S, Sahay S, Thakar M, Sahasrabuddhe S, Kakade M, Shete A, Shrotri A, Spentzou A, Tarragona T, Stevens G, Kochhar S, Excler JL, Fast P, Paranjape R Background & objectives:A phase 1 trial of adeno-associated virus based HIV-1 subtype C vaccine (tgAAC09) was conducted at two sites in Germany and Belgium and one site in India. This paper reports the safety and immunogenicity of tgAAC09 in healthy adult Indian volunteers. Methods: Between January 2005 and December 2006, 30 consenting volunteers were enrolled in the placebo controlled double-blind dose-escalation trial [3x10(9), 3x10(10) and 3x10(11) DNase resistant particles (DRPs)/ml].Single injection of the candidate vaccine was administered to ten volunteers randomized in 8:2 ratio in vaccine and placebo arms at e... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3881866 Sat, 31 Jul 2010 23:00:00 +0100 3881866 http://www.medworm.com/index.php?rid=3881865&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20716818%26dopt%3DAbstract The objective of the present study was to investigate the role of this ORF as a drug efflux pump, which might add new information in our understanding about the alternative mechanisms of drug resistance in mycobacteria. Methods: The open reading frame Rv2459 of Mycobacterium tuberculosis encoding a probable drug efflux protein has been cloned using pSD5 E.coli-Mycobacterium shuttle vector and overexpressed in M. tuberculosis H(37)Rv. This ORF was named as jefA. Overexpression of this gene in clones has been verified by real-time reverse transcription PCR. Minimum inhibitory concentrations (MICs) of recombinant as well as non-recombinant clones were determined by resazurin microtitre assay plate method (REMA) with and without efflux pump inhibitors carbonyl cyanide m-chlorophenylhydrazone (... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3881865 Sat, 31 Jul 2010 23:00:00 +0100 3881865 http://www.medworm.com/index.php?rid=3881864&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20716819%26dopt%3DAbstract This study showed a significant reduction in scores measuring subjective perceptions of stress in the patients treated with a cycle of REAC-CRM therapy. At the end-point the number of patients reporting symptoms of stress-related anxiety and depression on the PSM test was significantly reduced (P<0.001); in the placebo group no significant difference was highlighted. Interpretation & conclusions: NPPO therapy with a cycle of REAC-CRM was shown to reduce subjective perceptions of stress measured by the PSM test and in particular, symptoms of stress-related anxiety and depression. PMID: 20716819 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3881864 Sat, 31 Jul 2010 23:00:00 +0100 3881864 http://www.medworm.com/index.php?rid=3881863&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20716820%26dopt%3DAbstract This study was carried out to investigate the prevalence and determinants of depression in patients with established type 2 diabetes (T2DM) attending a tertiary care hospital in north India. Methods: Patients with established T2DM were evaluated for depression by administering the nine-item PHQ-9 (Hindi version). Binary logistic regression model was used to examine association between predictor variables and risk of depression. Results were expressed as odds ratio and 95 per cent confidence interval. Cronbach alpha was calculated to assess internal consistency of PHQ-9. Results: Patients with T2DM (n=300) were evaluated [147(49%) male and 153(51%) female]. The median duration of diabetes (IQ) was 8(4-13) yrs. Of the study patients, 68 (23%) met the criteria for major depression, 54 (18%) f... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3881863 Sat, 31 Jul 2010 23:00:00 +0100 3881863 http://www.medworm.com/index.php?rid=3881862&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20716821%26dopt%3DAbstract In this study, diagnostic tests on 102 male patients suspected with cannabis abuse were done. Liquid-liquid extraction of cannabinoids from urine was done and screened by Duquenois-Levine, fast blue B salt and p-dimethylaminobenzaldehyde (p-DMAB) tests. All the results were confirmed by high performance thin layer chromatography (HPTLC). Samples were considered positive for cannabis based on the positive indication in colour test and by detection of 11-nor-delta(9) tetrahydrocannabinol-9-carboxylic acid (THC-COOH) on HPTLC. Results: Based on the colour tests and HPTLC, cannabis abuse was detected in 64 of 102 patients tested. HPTLC method was found to be sensitive for detection and possible quantitation of THC-COOH. Interpretation & conclusion: We report the standardization and utility... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3881862 Sat, 31 Jul 2010 23:00:00 +0100 3881862 http://www.medworm.com/index.php?rid=3881861&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20716822%26dopt%3DAbstract Authors: Fioravanti A, Collodel G, Petraglia A, Nerucci F, Moretti E, Galeazzi M Background & objectives: Several in vitro studies have shown the importance of mechanical compression or hydrostatic pressure (HP) as a modulator of cartilage metabolism. The present study was undertaken to evaluate the in vitro effects of cyclical low HP (1-5 MPa) and continuous high HP (24 MPa) applied in the presence or absence of interleukin (IL)-1beta on human osteoarthritis (OA) chondrocytes. Methods: Chondrocytes obtained from OA cartilage were cultivated for 48 h and then exposed to pressurization in the presence or absence of IL-1beta. After pressurization, the culture medium was collected to detect the amount of proteoglycans (PG) and nitric oxide (NO) and the chondrocytes were immediately fi... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3881861 Sat, 31 Jul 2010 23:00:00 +0100 3881861 http://www.medworm.com/index.php?rid=3881860&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20716823%26dopt%3DAbstract In this study we evaluated the anti-ulcer efficacy of a polyherbal formulation with potent antioxidant activity in aspirin and pyloric ligature induced gastric ulcers in rats. Methods: The efficacy of the polyherbal formulation NR-ANX-C (composed of the extracts from Withania somnifera, Camellia sinensis, Ocimum sanctum, shilajith and triphala) was evaluated in terms of antioxidant potential as assessed in terms of protection from lipid peroxidation and the antiulcer activity as seen by the area of gastric lesions, gastric juice volume, gastric pH, total acidity and total adherent gastric mucus content. Results: In our study, NR-ANX-C (25 and 50 mg/kg) was more efficacious than ranitidine in reducing ulcer index in both the models. At the highest dose tested (50 mg/kg), NR-ANX-C was compar... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3881860 Sat, 31 Jul 2010 23:00:00 +0100 3881860 http://www.medworm.com/index.php?rid=3881859&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20716824%26dopt%3DAbstract Authors: Murhekar MV, Shah NK PMID: 20716824 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3881859 Sat, 31 Jul 2010 23:00:00 +0100 3881859 http://www.medworm.com/index.php?rid=3881858&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20716825%26dopt%3DAbstract Authors: Bhan A PMID: 20716825 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3881858 Sat, 31 Jul 2010 23:00:00 +0100 3881858 http://www.medworm.com/index.php?rid=3881857&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20716826%26dopt%3DAbstract Authors: Jacob John T PMID: 20716826 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3881857 Sat, 31 Jul 2010 23:00:00 +0100 3881857 http://www.medworm.com/index.php?rid=3881856&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20716827%26dopt%3DAbstract Authors: Suresh S, Aneja S PMID: 20716827 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3881856 Sat, 31 Jul 2010 23:00:00 +0100 3881856 http://www.medworm.com/index.php?rid=3849917&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20693581%26dopt%3DAbstract Authors: Lone Z, Puliyel JM PMID: 20693581 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3849917 Wed, 30 Jun 2010 23:00:00 +0100 3849917 http://www.medworm.com/index.php?rid=3849916&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20693582%26dopt%3DAbstract Authors: Jacob John T, Vashishtha VM, John SM, Sudarsanam TD PMID: 20693582 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3849916 Wed, 30 Jun 2010 23:00:00 +0100 3849916 http://www.medworm.com/index.php?rid=3849915&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20693583%26dopt%3DAbstract Authors: Pasrija SC PMID: 20693583 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3849915 Wed, 30 Jun 2010 23:00:00 +0100 3849915 http://www.medworm.com/index.php?rid=3849914&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20693584%26dopt%3DAbstract Authors: Greer F PMID: 20693584 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3849914 Wed, 30 Jun 2010 23:00:00 +0100 3849914 http://www.medworm.com/index.php?rid=3849913&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20693585%26dopt%3DAbstract Authors: Nandi SK, Roy S, Mukherjee P, Kundu B, De DK, Basu D Treatment of delayed union, malunion, and nonunion is a challenge to the orthopaedic surgeons in veterinary and human fields. Apart from restoration of alignment and stable fixation, in many cases adjunctive measures such as bone-grafting or use of bone-graft substitutes are of paramount importance. Bone-graft materials usually have one or more components: an osteoconductive matrix, which acts as scaffold to new bone growth; osteoinductive proteins, which support mitogenesis of undifferentiated cells; and osteogenic cells, which are capable of forming bone in the appropriate environment. Autologous bone remains the "gold standard" for stimulating bone repair and regeneration, but its availability may be limited and the proce... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3849913 Wed, 30 Jun 2010 23:00:00 +0100 3849913 http://www.medworm.com/index.php?rid=3849912&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20693586%26dopt%3DAbstract Authors: Zakeri S, Kakar Q, Ghasemi F, Raeisi A, Butt W, Safi N, Afsharpad M, Memon MS, Gholizadeh S, Salehi M, Atta H, Zamani G, Djadid ND Background & objectives: Species identification and information on transmission pattern of malaria parasite in any malaria endemic area is key to success for a malaria control programme. In this investigation, malaria diagnosis using molecular method was used to assess the transmission pattern of malaria parasite in three malaria endemic regions: Afghanistan, Iran and Pakistan. Methods: Blood samples were collected from the patients presenting with vivax malaria from Afghanistan (n = 108), Iran (n = 200) and Pakistan (n = 199). Malaria parasite detection was made by the gold standard (microscopy) and also nested-PCR assay, using 18S small sub-u... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3849912 Wed, 30 Jun 2010 23:00:00 +0100 3849912 http://www.medworm.com/index.php?rid=3849911&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20693587%26dopt%3DAbstract Authors: Ping WC, Keong CC, Bandyopadhyay A Background & objectives:Athletes in Malaysia need to perform in a hot and humid climate. Chronic supplementation of caffeine on endurance performance have been studied extensively in different populations. However, concurrent research on the effects of acute supplementation of caffeine on cardiorespiratory responses during endurance exercise in the Malaysian context especially in a hot and humid environment is unavailable. Methods: Nine heat adapted recreational Malaysian male runners (aged: 25.4 +/- 6.9 yr) who were nonusers of caffeine (23.7 +/-12.6 mg per day) were recruited in this placebo - controlled double - blind randomized study. Caffeine (5 mg per kg of body weight) or placebo was ingested in the form of a capsule one hour prior... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3849911 Wed, 30 Jun 2010 23:00:00 +0100 3849911 http://www.medworm.com/index.php?rid=3849910&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20693588%26dopt%3DAbstract Authors: Anantharaman R, Bhansali A, Bhadada SK, Kohli HS, Dutta P, Walia R, Jayaprakash P, Upreti V Background & objectives:The efficacy of the combination of angiotensin receptor blockers (ARBs) and angiotensin converting enzyme (ACE) inhibitors in patients of type 1 diabetes mellitus (DM) with nephropathy is debatable. The antialbuminuric efficacy of dual blockade in patients of type 1 DM with micro- or macroabuminuria were evaluated. Methods: In this open label observational study 30 patients (20 male 10 female) with type 1 DM were included who were initially treated with telmisartan 80 mg for eight weeks followed by addition of ramipril 10 mg for a further eight weeks. Albuminuria reduction was studied at the end of each phase. Results: Therapy with telmisartan for 8 wk result... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3849910 Wed, 30 Jun 2010 23:00:00 +0100 3849910 http://www.medworm.com/index.php?rid=3849909&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20693589%26dopt%3DAbstract Authors: Mahdi B, Mahesh PA, Savitha RM, Kumar P, Jayaraj BS, Ramachandra NB Background & objectives: Family history is an important risk factor for the development of asthma, contingent upon genetic and environment interaction. Since there is paucity of data on asthma inheritance in Indian population, the present study was undertaken to investigate the inheritance patterns of asthma and the effect of family history and consanguineous marriage on asthma inheritance. Methods: A total of 200 families, 100 index children and 100 index adults with clinically diagnosed asthma, along with 400 non-asthmatic children and adults as controls were selected for the present study. Information about the family history of each patients and controls was collected and analyzed pedigrees were also c... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3849909 Wed, 30 Jun 2010 23:00:00 +0100 3849909 http://www.medworm.com/index.php?rid=3849908&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20693590%26dopt%3DAbstract Authors: Kasapoglu B, Turkay C, Bayram Y, Koca C Background & objectives: The aim of this study is to know if the liver function tests (LFT), especially gamma glutamyl transferase (GGT), have a predictive value in diagnosis of metabolic syndrome (MS). Methods: A cross-sectional, single-center study was carried out with 908 subjects. Four hundred and forty two of these subjects were diagnosed with MS with IDF criteria; while other 466 were sex and age matched healthy control subjects. Blood pressure, liver function tests, fasting blood glucose levels and lipid profile of the subjects were recorded. Results: The mean values of alanine amino transferase (ALT), aspartate aminotransferase (AST) and GGT levels were statistically significantly higher in MS group. The mean values of liver ... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3849908 Wed, 30 Jun 2010 23:00:00 +0100 3849908 http://www.medworm.com/index.php?rid=3849907&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20693591%26dopt%3DAbstract Authors: Ramu P, Mahesh Kumar KN, Shewade DG, Swaminathan RP, Dutta TK, Balachander J, Adithan C Background & objectives: Several studies reported the polymorphisms of beta1-adrenergic receptor gene in healthy volunteers and its influence on cardiovascular disorders. We investigated the genotype and allele frequencies of Ser49Gly and Arg389Gly polymorphism in healthy volunteers of South Indian Tamilian population vis-à-vis other major ethnic groups. Methods: The genetic variants were determined by using Taqman 5' nuclease assay- real time PCR analysis in 533 normal healthy volunteers (18-60 yr; M=290; F=243). The allelic discrimination analysis was done by 7700 SDS software. Results: The estimated genotype and allele frequencies of Ser49Gly and Arg389Gly polymorphism were compar... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3849907 Wed, 30 Jun 2010 23:00:00 +0100 3849907 http://www.medworm.com/index.php?rid=3849906&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20693592%26dopt%3DAbstract The objectives were to determine the aetiology, study the clinical features in the affected individuals and, important epidemiological and environmental factors. The nature of public health response and effectiveness of the control measures were also evaluated. Methods: Real time reverse transcriptase polymerase chain reaction was performed on throat swabs collected from 82 suspected cases to determine the influenza types (A or B) and sub-types [pandemic (H1N1) 2009, as well as seasonal influenza H1N1, H3N2]. Haemagglutination inhibition assay was performed on serum samples collected from entire school population (N = 415) to detect antibodies for pandemic (H1N1) 2009, seasonal H1N1, H3N2 and influenza B/Yamagata and B/Victoria lineages. Antibody titres >/=10 for pandemic (H1N1) 2009 an... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3849906 Wed, 30 Jun 2010 23:00:00 +0100 3849906 http://www.medworm.com/index.php?rid=3849905&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20693593%26dopt%3DAbstract This study was carried out to compare pyrazinamide susceptibility testing by MGIT 960 and two rapid pyrazinamidase activity tests. Methods: Pyrazinamide susceptibility was tested in 136 clinical isolates of Mycobacterium tuberculosis by MGIT 960 and pyrazinamidase activity was tested by classical Wayne's method and modified PZase agar method. Results: There was 88.9 per cent concordance between MGIT 960 and classical Wayne's method and 93.38 per cent with modified method for pyrazinamidase activity. Using MGIT 960 results as gold standard the sensitivity and specificity of Wayne's method was 88.15 and 90 per cent respectively and that of modified method was 89.4 and 98.3 per cent. Interpretation & conclusions: Our study demonstrates that the modified pyrazinamidase activity test can be... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3849905 Wed, 30 Jun 2010 23:00:00 +0100 3849905 http://www.medworm.com/index.php?rid=3849904&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20693594%26dopt%3DAbstract This study was aimed at determining the pattern of presentation of abdominal tuberculosis on ultrasonography (USG) in HIV positive patients. Methods: This retrospective study was carried at the ART Centre, Sir Sunderlal Hospital, Banaras Hindu University, Varanasi, between March 2005 to July 2007. HIV positive patients (n=2453) with prolonged fever, abdominal pain/distension, altered bowel habits and diarrhoea underwent ultrasonography for tuberculosis of abdomen. The different ultrasonological findings in abdominal tuberculosis were noted. CD(4) counts of these patients were also recorded. Results: Of the total 2453 patients, 244 showed findings suggestive of abdominal tuberculosis. Lymphadenopathy with predominantly hypoechoic/necrotic echotexture was seen in 158/244 (64.8%) patients. Sp... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3849904 Wed, 30 Jun 2010 23:00:00 +0100 3849904 http://www.medworm.com/index.php?rid=3849903&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20693595%26dopt%3DAbstract Authors: Singla R, Sharma SK, Mohan A, Makharia G, Sreenivas V, Jha B, Kumar S, Sarda P, Singh S Background & objectives: Antituberculosis (anti-TB) drug induced hepatotoxicity (DIH) is the most common side effect leading to interruption of therapy. Wide variations have been found in the reported incidence of hepatotoxicity during short-course chemotherapy. Several risk factors for hepatotoxicity have been suggested in previous studies. We undertook a prospective case-control study to assess the role of these putative risk factors in the development of DIH in patients receiving anti-TB treatment. Methods: One hundred and seventy five consecutive cases with a diagnosis of anti-TB DIH were compared with 428 consecutive controls who took anti-TB drugs for the full duration of chemothe... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3849903 Wed, 30 Jun 2010 23:00:00 +0100 3849903 http://www.medworm.com/index.php?rid=3849902&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20693596%26dopt%3DAbstract Authors: Chhabra SK, Yasir A, Chaudhry K, Shah B Background & objectives: Exposure to ozone and asthma are both associated with increased oxidative stress. Exposure to ozone therefore, may potentiate the airway response to allergens. We undertook this study to investigate the effect of ozone exposure on airway response to ovalbumin in sensitized guinea pigs and its modulation by dietary supplementation with antioxidant vitamins C and E. Methods: After in vivo measurements of specific airways conductance (SGaw) and airway hyperresponsiveness (AHR) to inhaled histamine, guinea pigs were sensitized to ovalbumin and divided into three groups: (i) sensitized; (ii) sensitized and exposed daily to ozone; and (iii) sensitized, exposed daily to ozone and given dietary supplementation with v... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3849902 Wed, 30 Jun 2010 23:00:00 +0100 3849902 http://www.medworm.com/index.php?rid=3849901&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20693597%26dopt%3DAbstract Authors: Shriram V, Jahagirdar S, Latha C, Kumar V, Dhakephalkar P, Rojatkar S, Shitole MG Background & objectives: The multiple drug resistance (MDR) is a serious health problem and major challenge to the global drug discovery programmes. Most of the genetic determinants that confer resistance to antibiotics are located on R-plasmids in bacteria. The present investigation was undertaken to investigate the ability of organic extract of the fruits of Helicteres isora to cure R-plasmids from certain clinical isolates. Methods: Active fractions demonstrating antibacterial and antiplasmid activities were isolated from the acetone extracts of shade dried fruits of H. isora by bioassay guided fractionation. Minimal inhibitory concentration (MIC) of antibiotics and organic extracts was de... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3849901 Wed, 30 Jun 2010 23:00:00 +0100 3849901 http://www.medworm.com/index.php?rid=3849900&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20693598%26dopt%3DAbstract Authors: Chandran SP, Kenneth J PMID: 20693598 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3849900 Wed, 30 Jun 2010 23:00:00 +0100 3849900 http://www.medworm.com/index.php?rid=3849899&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20693599%26dopt%3DAbstract Authors: Mohapatra PR PMID: 20693599 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3849899 Wed, 30 Jun 2010 23:00:00 +0100 3849899 http://www.medworm.com/index.php?rid=3849898&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20693600%26dopt%3DAbstract Authors: Paramasivan R, Thenmozhi V, Thangaratham PS, Rajendran R, Tewari SC, Dhananjeyan KJ, Tyagi BK PMID: 20693600 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3849898 Wed, 30 Jun 2010 23:00:00 +0100 3849898 http://www.medworm.com/index.php?rid=3849897&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20693601%26dopt%3DAbstract Authors: Manjunatha N PMID: 20693601 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3849897 Wed, 30 Jun 2010 23:00:00 +0100 3849897 http://www.medworm.com/index.php?rid=3849896&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20693602%26dopt%3DAbstract Authors: Mahajan PB PMID: 20693602 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3849896 Wed, 30 Jun 2010 23:00:00 +0100 3849896 http://www.medworm.com/index.php?rid=3849895&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20693603%26dopt%3DAbstract Authors: Biswas T PMID: 20693603 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3849895 Wed, 30 Jun 2010 23:00:00 +0100 3849895 http://www.medworm.com/index.php?rid=3625914&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20516527%26dopt%3DAbstract Authors: Sharma AM PMID: 20516527 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3625914 Fri, 30 Apr 2010 23:00:00 +0100 3625914 http://www.medworm.com/index.php?rid=3625913&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20516528%26dopt%3DAbstract Authors: Minh HV, Nga PT PMID: 20516528 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3625913 Fri, 30 Apr 2010 23:00:00 +0100 3625913 http://www.medworm.com/index.php?rid=3625912&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20516529%26dopt%3DAbstract Authors: Vega GL PMID: 20516529 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3625912 Fri, 30 Apr 2010 23:00:00 +0100 3625912 http://www.medworm.com/index.php?rid=3625911&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20516530%26dopt%3DAbstract Authors: Kutty BM, Raju TR PMID: 20516530 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3625911 Fri, 30 Apr 2010 23:00:00 +0100 3625911 http://www.medworm.com/index.php?rid=3625910&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20516531%26dopt%3DAbstract Authors: Jaganjac M The activation process of granulocytes is accompanied by the intense production of reactive oxygen species (ROS). Overproduction of ROS is cytotoxic, damages macromolecules and can lead to the occurrence of lipid peroxidation. Cellular defense against the toxicity of ROS is enhancement of detoxifying enzymes activation. Regulation of many detoxifying enzymes is mediated by the antioxidant response element (ARE) that is located in the promoter region of related genes. In eukaryotes, there are only few transcription factors known to be activated by ROS. One of them is NF-E2-related factor 2 (Nrf2). Normally, Nrf2 is present in the cytoplasm as an inactive Keap1-Nrf2 complex. However, after direct attack by ROS, Nrf2 is released from Keap1 repression and translocated i... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3625910 Fri, 30 Apr 2010 23:00:00 +0100 3625910 http://www.medworm.com/index.php?rid=3625909&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20516532%26dopt%3DAbstract Authors: Madhavi Y, Puliyel JM, Mathew JL, Raghuram N, Phadke A, Shiva M, Srinivasan S, Paul Y, Srivastava RN, Parthasarathy A, Gupta S, Ranga U, Lakshmi VV, Joshi N, Nath I, Gulhati CM, Chatterjee P, Jain A, Priya R, Dasgupta R, Sridhar S, Dabade G, Gopakumar KM, Abrol D, Santhosh MR, Srivastava S, Visalakshi S, Bhargava A, Sarojini NB, Sehgal D, Selvaraj S, Banerji D India has over a century old tradition of development and production of vaccines. The Government rightly adopted self-sufficiency in vaccine production and self-reliance in vaccine technology as its policy objectives in 1986. However, in the absence of a full-fledged vaccine policy, there have been concerns related to demand and supply, manufacture vs. import, role of public and private sectors, choice of vaccines, new a... The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3625909 Fri, 30 Apr 2010 23:00:00 +0100 3625909 http://www.medworm.com/index.php?rid=3625908&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20516533%26dopt%3DAbstract CONCLUSION: These results indicate that in non-diabetic Asian Indians, visceral, but not subcutaneous component of abdominal fat is associated with insulin resistance, cardiovascular risk factors and metabolic syndrome. PMID: 20516533 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3625908 Fri, 30 Apr 2010 23:00:00 +0100 3625908 http://www.medworm.com/index.php?rid=3625907&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20516534%26dopt%3DAbstract CONCLUSION: Our data suggest that yoga has a beneficial effect on P300 and thus can be incorporated along with the conventional medical therapy for improving cognitive brain functions in diabetes. PMID: 20516534 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3625907 Fri, 30 Apr 2010 23:00:00 +0100 3625907 http://www.medworm.com/index.php?rid=3625906&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20516535%26dopt%3DAbstract CONCLUSION: TC/HDL-C ratio, TG/HDL-C, ratio, Non-HDL-C, WC, TG, and TC can be used as the markers of insulin resistance and CVD risk in T2D patients. PMID: 20516535 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3625906 Fri, 30 Apr 2010 23:00:00 +0100 3625906 http://www.medworm.com/index.php?rid=3625905&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20516536%26dopt%3DAbstract CONCLUSIONS: Incidence of severe clinical pneumonia is comparable with other studies from India but that of suspected meningitis is higher. Although rates of Hib meningitis cannot be calculated from a hospital-based study, there is evidence of Hib meningitis in these study settings. Hib carriage prevalence indicates that Hib is present and circulating in these study areas. There is a significant burden of pneumonia and meningitis among children in India. Continued strengthening of laboratory capacity and bacterial surveillance systems are necessary. PMID: 20516536 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3625905 Fri, 30 Apr 2010 23:00:00 +0100 3625905 http://www.medworm.com/index.php?rid=3625904&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20516537%26dopt%3DAbstract CONCLUSION: The frequency of the MTHFR 677 TT genotype is rare as compared to 1298 CC genotype in the population studied. There was no association between 677 C-->T and 1298 A-->C polymorphisms and risk of CRC either individually or in combination. The homozygous state for 1298 A-->C polymorphism appears to slightly lower risk of CRC. This needs to be confirmed with a larger sample size. PMID: 20516537 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3625904 Fri, 30 Apr 2010 23:00:00 +0100 3625904 http://www.medworm.com/index.php?rid=3625903&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20516538%26dopt%3DAbstract CONCLUSION: Treatment regimen of group B was more convenient to the patients because less number of visits required and cheap. No side effects were seen. A follow up study is required to see long term effects. PMID: 20516538 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3625903 Fri, 30 Apr 2010 23:00:00 +0100 3625903 http://www.medworm.com/index.php?rid=3625902&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20516539%26dopt%3DAbstract CONCLUSION: Our results suggest that cabergoline treatment in infertile women with prolactinemia is more effective. It lowers prolactin with better tolerability and much more effective in the achievement of pregnancy. PMID: 20516539 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3625902 Fri, 30 Apr 2010 23:00:00 +0100 3625902 http://www.medworm.com/index.php?rid=3625901&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20516540%26dopt%3DAbstract CONCLUSION: The normal range and threshold for DNA damage as a predictor of male fertility potential and technique which could assess the sperm DNA damage are necessary to lower the trauma of couples experiencing recurrent spontaneous abortion or failure in ART. PMID: 20516540 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3625901 Fri, 30 Apr 2010 23:00:00 +0100 3625901 http://www.medworm.com/index.php?rid=3625900&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20516541%26dopt%3DAbstract CONCLUSIONS: Considerable difference exists in the bioavailability of the three test compounds. Curcumin could be traced in the brain following its administration. Bioavailability of curcumin can be improved by co-administration with piperine. PMID: 20516541 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3625900 Fri, 30 Apr 2010 23:00:00 +0100 3625900 http://www.medworm.com/index.php?rid=3625899&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20516542%26dopt%3DAbstract CONCLUSIONS: Considerable difference exists in the bioavailability of the three test compounds. Curcumin could be traced in the brain following its administration. Bioavailability of curcumin can be improved by co-administration with piperine. PMID: 20516542 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3625899 Fri, 30 Apr 2010 23:00:00 +0100 3625899 http://www.medworm.com/index.php?rid=3625898&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20516543%26dopt%3DAbstract CONCLUSIONS: Our findings showed hypoglycaemic effect of fermented P. farinosus (G30801) in experimental diabetes rat model fed with high fat diet. PMID: 20516543 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3625898 Fri, 30 Apr 2010 23:00:00 +0100 3625898 http://www.medworm.com/index.php?rid=3625897&cid=s_37924_61_f&fid=37924&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20516544%26dopt%3DAbstract CONCLUSIONS: Novel finding of active B19 infection in non-occlusive gangrene of the bowel may be causal rather than casual. PMID: 20516544 [PubMed - in process] (Source: The Indian Journal of Medical Research) The Indian Journal of Medical Research journals http://www.medworm.com/rss/comments.php?id=3625897 Fri, 30 Apr 2010 23:00:00 +0100 3625897