MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'The Journal of Clinical Endocrinology and Metabolism' source. Sat, 20 Mar 2010 14:13:31 +0100 http://www.medworm.com/index.php?rid=3383501&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20237162%26dopt%3DAbstract Conclusion: Here we demonstrate for the first time that plasma chemerin levels are significantly heritable and identified a novel role for chemerin as a stimulator of angiogenesis. PMID: 20237162 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3383501 Wed, 17 Mar 2010 00:00:00 +0100 3383501 http://www.medworm.com/index.php?rid=3383500&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20237163%26dopt%3DAbstract Conclusion: Our findings suggest that increased sympathetic and decreased parasympathetic nervous system activity is associated with metabolic syndrome, whereas HPA axis activity is not. PMID: 20237163 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3383500 Wed, 17 Mar 2010 00:00:00 +0100 3383500 http://www.medworm.com/index.php?rid=3383499&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20237164%26dopt%3DAbstract Conclusion: The novel Mc4/TSI is a functional indicator of GO activity and severity. PMID: 20237164 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3383499 Wed, 17 Mar 2010 00:00:00 +0100 3383499 http://www.medworm.com/index.php?rid=3383498&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20237165%26dopt%3DAbstract Conclusions: The 1-3% detection rates of three recently published series have not been realized at our center where we studied a group using criteria making patients more likely to have hypercortisolism. Our results do not support the validity of screening patients without clinical features of Cushing's syndrome in the diabetes clinic. PMID: 20237165 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3383498 Wed, 17 Mar 2010 00:00:00 +0100 3383498 http://www.medworm.com/index.php?rid=3383497&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20237166%26dopt%3DAbstract Conclusion: Two KISS1 mutations were identified in unrelated patients with idiopathic CPP. The p.P74S variant was associated with higher kisspeptin resistance to degradation in comparison with the wild type, suggesting a role for this mutation in the precocious puberty phenotype. PMID: 20237166 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3383497 Wed, 17 Mar 2010 00:00:00 +0100 3383497 http://www.medworm.com/index.php?rid=3383496&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20237167%26dopt%3DAbstract Conclusions: In post- vs. pre-uterine-contraction specimens, significantly lower HSCOREs in DC nuclei, but not IT, and unchanging GR levels in DCs and ITs suggest that functional P4 withdrawal may occur in DCs and is unlikely to involve the GR. Nuclear extracts from DC monolayer cultures express steroid-regulated PR-A and PR-B and constitutive GR. PMID: 20237167 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3383496 Wed, 17 Mar 2010 00:00:00 +0100 3383496 http://www.medworm.com/index.php?rid=3383495&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20237168%26dopt%3DAbstract Conclusions: Adiponectin, an inverse marker of metabolic derangements, was associated with desaturase activity, indicating that possible functional alterations in fatty acid metabolism may already be present in young healthy adolescent females. PMID: 20237168 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3383495 Wed, 17 Mar 2010 00:00:00 +0100 3383495 http://www.medworm.com/index.php?rid=3383494&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20237169%26dopt%3DAbstract Conclusions: Pioglitazone use in combination with insulin resulted in a sustained improved glycemic control and allowed the treatment regimens to be simplified and the insulin doses reduced. PMID: 20237169 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3383494 Wed, 17 Mar 2010 00:00:00 +0100 3383494 http://www.medworm.com/index.php?rid=3383505&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20233782%26dopt%3DAbstract Conclusion: The expression profile of placental hGH/CSH genes in placenta is altered in pregnancies accompanied by SGA and LGA compared with AGA newborns, and thus, it may directly affect the circulating fetal and maternal placental GH and placental lactogen levels. PMID: 20233782 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3383505 Tue, 16 Mar 2010 00:00:00 +0100 3383505 http://www.medworm.com/index.php?rid=3383504&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20233783%26dopt%3DAbstract Conclusions: These results indicate that sst5TMD4 is related to the reduced ability of octreotide at normalizing hormone secretion in poorly responsive tumors in vivo. Further studies will help to evaluate the potential use of sst5TMD4 expression in surgically removed pituitary adenomas as a predictor of the subsequent response of different pituitary tumors to SSA therapy. PMID: 20233783 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3383504 Tue, 16 Mar 2010 00:00:00 +0100 3383504 http://www.medworm.com/index.php?rid=3383503&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20233784%26dopt%3DAbstract Conclusions: rhIGF-I/rhIGFBP-3 is well tolerated and clinically effective in subjects with SIR. PMID: 20233784 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3383503 Tue, 16 Mar 2010 00:00:00 +0100 3383503 http://www.medworm.com/index.php?rid=3383502&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20233785%26dopt%3DAbstract Conclusion: Neither CAG nor GGn repeat lengths are statistically significant modifiers of genital virilization in females with 21OHD. PMID: 20233785 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3383502 Tue, 16 Mar 2010 00:00:00 +0100 3383502 http://www.medworm.com/index.php?rid=3374957&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20228162%26dopt%3DAbstract Conclusion: Infants of women with PCOS were more likely to be large for gestational age. Female offspring of affected women have lower cord blood A levels; other cord blood androgen levels do not differ compared with female control offspring. Cord blood E2 levels are also significantly decreased in PCOS, without any difference in the testosterone to E2 ratio, suggesting decreased fetal or placental production of steroids. PMID: 20228162 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3374957 Fri, 12 Mar 2010 00:00:00 +0100 3374957 http://www.medworm.com/index.php?rid=3374956&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20228163%26dopt%3DAbstract Conclusions: Physical inactivity decreases HDL cholesterol, at least in part, through CETP up-regulation. PMID: 20228163 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3374956 Fri, 12 Mar 2010 00:00:00 +0100 3374956 http://www.medworm.com/index.php?rid=3374955&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20228164%26dopt%3DAbstract Conclusion: It is the first evidence showing that sst2 receptors can be internalized in sst2-expressing neuroendocrine tumors in patients under octreotide therapy, providing clues about sst2 receptor biology and trafficking dynamics in patients. PMID: 20228164 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3374955 Fri, 12 Mar 2010 00:00:00 +0100 3374955 http://www.medworm.com/index.php?rid=3374954&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20228165%26dopt%3DAbstract Conclusions: Patients with biochemically mild PHPT do not have evidence of increased left ventricular mass, diastolic dysfunction, or increased valvular calcifications. However, the data support an association between low vitamin D levels and the development of left ventricular hypertrophy in this disorder. Finally, the increased serum calcium and PTH levels in those with diastolic dysfunction suggest that disease severity may determine the presence of cardiac manifestations in PHPT. PMID: 20228165 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3374954 Fri, 12 Mar 2010 00:00:00 +0100 3374954 http://www.medworm.com/index.php?rid=3374953&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20228166%26dopt%3DAbstract Conclusions: Of the investigated FGFs, only FGF1 is secreted from sc WAT and predominantly so from the adipocyte fraction. The activity in adipocyte cultures and lack of secretion into the circulation suggest that FGF1 acts as an auto- or paracrine factor. FGF1 levels are increased in obesity but unaffected by weight reduction, suggesting a primary defect in obese individuals. In conclusion, FGF1 may play a superior role among the FGFs in sc WAT and obesity development. PMID: 20228166 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3374953 Fri, 12 Mar 2010 00:00:00 +0100 3374953 http://www.medworm.com/index.php?rid=3374952&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20228167%26dopt%3DAbstract Conclusion: The prevalence of GHD in Dutch patients with AIH is 0.4% (two of 515). PMID: 20228167 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3374952 Fri, 12 Mar 2010 00:00:00 +0100 3374952 http://www.medworm.com/index.php?rid=3357497&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20219892%26dopt%3DAbstract Conclusions: SMLC is not different between black and white obese adolescents who have similar total body adiposity but lower visceral fat in blacks. The lack of association between IS and SMLC after adjusting for total adiposity suggest that muscle fat does not make a unique contribution to IS in this group of obese adolescents regardless of race. PMID: 20219892 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3357497 Wed, 10 Mar 2010 00:00:00 +0100 3357497 http://www.medworm.com/index.php?rid=3357519&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20215394%26dopt%3DAbstract Conclusions: Although PHEO/PGL are rarely diagnosed during childhood, the pediatric provider should be able to recognize and screen for such tumors, particularly in the context of a known genetic predisposition. Optimal care of these children includes a multidisciplinary team approach at centers experienced in the evaluation and treatment of these uncommon yet fascinating endocrine neoplasms. PMID: 20215394 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3357519 Tue, 09 Mar 2010 00:00:00 +0100 3357519 http://www.medworm.com/index.php?rid=3357514&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20215395%26dopt%3DAbstract Conclusions: Africans presented lower IGF-I levels than Caucasians due to an accelerated decline in serum IGF-I concentration prior to 40 yr of age. Strong associations of low serum IGF-I with blood pressure and arterial stiffness in young Africans suggest that the loss of cardiometabolic protection by IGF-I could predispose them to earlier disease onset. PMID: 20215395 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3357514 Tue, 09 Mar 2010 00:00:00 +0100 3357514 http://www.medworm.com/index.php?rid=3357510&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20215396%26dopt%3DAbstract Conclusions: The lack of consistency between our and previously performed studies might represent spurious results or chance findings in our or the earlier studies, differences in criteria used to select the study populations, or a real difference between populations, i.e. different genes contributing to disease risk. These results once again confirm the importance of replication in genetic association approaches. PMID: 20215396 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3357510 Tue, 09 Mar 2010 00:00:00 +0100 3357510 http://www.medworm.com/index.php?rid=3357506&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20215397%26dopt%3DAbstract Conclusions: Our findings support the important contribution of GNPDA2, BCDIN3D/FAIM2, SH2B1, FTO, and KCTD15 in the regulation of adiposity, which in turn affects T2D risk in Chinese. PMID: 20215397 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3357506 Tue, 09 Mar 2010 00:00:00 +0100 3357506 http://www.medworm.com/index.php?rid=3357499&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20215398%26dopt%3DAbstract Conclusions: Acromegaly is associated with an increased prevalence of colonic diverticula. In addition to the known irreversible effect of GH excess on collagen of joints and cardiac valves, this observation indicates an irreversible effect of GH and/or IGF-I on the collagen in the colon. PMID: 20215398 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3357499 Tue, 09 Mar 2010 00:00:00 +0100 3357499 http://www.medworm.com/index.php?rid=3357498&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20215399%26dopt%3DAbstract Conclusions: Spine and FN bone loss accelerates in FSH stage 3. Bone loss also began to accelerate 2 yr before the FMP with the greatest loss occurring in the 2 yr after the FMP. Bone loss rates in both spine and FN BMD were greater in nonobese women than obese women. PMID: 20215399 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3357498 Tue, 09 Mar 2010 00:00:00 +0100 3357498 http://www.medworm.com/index.php?rid=3350507&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20207825%26dopt%3DAbstract Conclusions: The modulatory effects of E2 and R at therapeutic doses on GH action are different. R during GH therapy exerts a greater inhibitory effect on lipid oxidation and protein anabolism compared to E2. PMID: 20207825 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3350507 Fri, 05 Mar 2010 00:00:00 +0100 3350507 http://www.medworm.com/index.php?rid=3350506&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20207826%26dopt%3DAbstract Conclusions: TAL and high Treg frequency in primary thyroid tumors correlates with more aggressive disease. Future prospective studies may identify Treg frequency as a predictive factor in PTC, and the suppressive effects of Treg should be considered in the design of immune-based therapies. PMID: 20207826 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3350506 Fri, 05 Mar 2010 00:00:00 +0100 3350506 http://www.medworm.com/index.php?rid=3350505&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20207827%26dopt%3DAbstract Conclusions: The UGT1A1*28 genotype and male gender predict an increased incidence of LFT abnormalities during PEG therapy in acromegaly. PMID: 20207827 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3350505 Fri, 05 Mar 2010 00:00:00 +0100 3350505 http://www.medworm.com/index.php?rid=3350504&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20207828%26dopt%3DAbstract Conclusions: In type 1 diabetic patients without endogenous insulin secretion, GLP-1 decreases the glucagon secretion as well as the arginine-induced glucagon response during hyperglycemia. GLP-1 induced endogenous insulin secretion in one of nine type 1 diabetic patients previously classified as being without endogenous insulin secretion. PMID: 20207828 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3350504 Fri, 05 Mar 2010 00:00:00 +0100 3350504 http://www.medworm.com/index.php?rid=3350503&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20207829%26dopt%3DAbstract Conclusion: IGF-based GH dosing is clinically feasible in both GHD and ISS patients, although GH dose requirements and auxological outcomes are distinct between these groups. This suggests a degree of both GH and IGF insensitivity in subjects with ISS that requires specific management strategies to optimize growth during GH therapy. PMID: 20207829 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3350503 Fri, 05 Mar 2010 00:00:00 +0100 3350503 http://www.medworm.com/index.php?rid=3350502&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20207830%26dopt%3DAbstract Conclusion: ETA/ETB receptor blockade enhances basal and insulin-stimulated glucose uptake in IR subjects. ET-1 directly impairs glucose uptake in skeletal muscle cells via a receptor-dependent mechanism. These data suggest that ET-1 regulates glucose metabolism via receptor-dependent mechanisms in IR subjects. PMID: 20207830 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3350502 Fri, 05 Mar 2010 00:00:00 +0100 3350502 http://www.medworm.com/index.php?rid=3338781&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20200332%26dopt%3DAbstract Conclusions: A polymorphic variant, D19S884, in FBN3 is associated with risk of PCOS. POMC is also a candidate gene of interest. PMID: 20200332 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3338781 Wed, 03 Mar 2010 00:00:00 +0100 3338781 http://www.medworm.com/index.php?rid=3338780&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20200333%26dopt%3DAbstract Conclusion: Oral contraception with ethinylestradiol plus gestodene induces an increase in the production rate of apoB-containing lipoproteins all along the VLDL-->IDL-->LDL cascade. The increased production rate of apoB in LDL is counterbalanced by a higher fractional catabolic rate of apoB in LDL, thus precluding an increase in the concentration of atherogenic LDL particles. PMID: 20200333 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3338780 Wed, 03 Mar 2010 00:00:00 +0100 3338780 http://www.medworm.com/index.php?rid=3338779&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20200334%26dopt%3DAbstract Conclusion: Immunohistochemistry of the human normal adrenal cortex for CYP11B2 and CYP11B1 revealed a variegated zonation with cell clusters constitutively expressing CYP11B2. This technique may provide a pathological confirmatory diagnosis of adrenocortical adenomas. PMID: 20200334 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3338779 Wed, 03 Mar 2010 00:00:00 +0100 3338779 http://www.medworm.com/index.php?rid=3338778&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20200335%26dopt%3DAbstract Conclusions: Abdominal fat is increased in anovulatory women due to a significant increase in SAF and not in intraabdominal fat. SAF and especially abdominal and trunk fat accumulation are associated with anovulation. PMID: 20200335 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3338778 Wed, 03 Mar 2010 00:00:00 +0100 3338778 http://www.medworm.com/index.php?rid=3338777&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20200336%26dopt%3DAbstract Conclusion: Simplicity, velocity, sensitivity, specificity, and the availability of pediatric reference data allow application of our new method in clinical routine as well as in research settings. PMID: 20200336 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3338777 Wed, 03 Mar 2010 00:00:00 +0100 3338777 http://www.medworm.com/index.php?rid=3338776&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20200337%26dopt%3DAbstract Conclusion: The current results suggest differential effects of PPARdelta in males and females. PMID: 20200337 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3338776 Wed, 03 Mar 2010 00:00:00 +0100 3338776 http://www.medworm.com/index.php?rid=3338775&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20203334%26dopt%3DAbstract Authors: Haugen BR, Kane MA Patients with distant, or extracervical, metastases from differentiated thyroid cancer require multimodality diagnostic, therapeutic, and monitoring approaches. Whereas cure is the initial goal, especially in those with small, radioiodine-avid pulmonary metastases, improved survival and management of symptoms become the primary objective in many patients with persistent disease, especially those with bone metastases. Levothyroxine therapy with suppression of serum TSH is a primary therapy in all patients with advanced differentiated thyroid cancer, and this therapy has been shown to improve overall survival and slow disease progression. Radioiodine is also an important systemic therapy for those patients with radioiodine-avid disease who respond to this targ... The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3338775 Mon, 01 Mar 2010 00:00:00 +0100 3338775 http://www.medworm.com/index.php?rid=3332038&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20194706%26dopt%3DAbstract Conclusion: Our data demonstrate the hypothalamic origin of the gonadotropin deficiency in these genetic forms of normosmic CHH. Neurokinin B and NK3R therefore both play a crucial role in hypothalamic GnRH release in humans. PMID: 20194706 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3332038 Mon, 01 Mar 2010 00:00:00 +0100 3332038 http://www.medworm.com/index.php?rid=3332037&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20194707%26dopt%3DAbstract Conclusions: Lp-PLA2 activity and index was associated with presence of CAD among African-Americans and Caucasians undergoing coronary angiography. The findings suggest an independent impact of vascular inflammation among African-Americans as contributory to CAD risk and underscore the importance of Lp-PLA2 as a cardiovascular risk factor. PMID: 20194707 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3332037 Mon, 01 Mar 2010 00:00:00 +0100 3332037 http://www.medworm.com/index.php?rid=3332036&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20194708%26dopt%3DAbstract Conclusions: The lower levels and greater relative changes in ghrelin values reported by the sandwich assays are consistent with greater assay specificity. When applied to the nutrient study, the sandwich assays were better able to distinguish the different responses to different nutrients than were the RIAs. PMID: 20194708 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3332036 Mon, 01 Mar 2010 00:00:00 +0100 3332036 http://www.medworm.com/index.php?rid=3332035&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20194709%26dopt%3DAbstract Conclusions: Bone density showed a high degree of tracking over 3 yr in children and adolescents. Healthy children with low bone density will likely continue to have low bone density unless effective interventions are instituted. PMID: 20194709 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3332035 Mon, 01 Mar 2010 00:00:00 +0100 3332035 http://www.medworm.com/index.php?rid=3332034&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20194710%26dopt%3DAbstract Conclusions: Our data suggest that elevated aldosterone levels is associated with elevated circulating resistin levels and cardiac morphological changes independently of the presence of SM. PMID: 20194710 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3332034 Mon, 01 Mar 2010 00:00:00 +0100 3332034 http://www.medworm.com/index.php?rid=3332033&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20194711%26dopt%3DAbstract Conclusions: GLP-1 exerts its effect on gastric emptying, appetite, food intake, and glucagon secretion directly, although secretion of amylin may contribute to some of these effects in healthy control subjects. PMID: 20194711 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3332033 Mon, 01 Mar 2010 00:00:00 +0100 3332033 http://www.medworm.com/index.php?rid=3332032&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20194712%26dopt%3DAbstract Conclusions: Recent advances in genetics, such as the identification of Kir6.2 mutations and the responsible genes for several forms of maturity onset diabetes of the young (MODY), have established precedents linking specifically effective therapies to defined diabetes subtypes. The recent increase in identified polygenic factors related to type 2 diabetes and our understanding of the pathogenesis of diabetes provide potential opportunities to individualize therapy. To further this process, we recommend expanded analysis of existing data sources and the development of new basic and clinical research studies, including a greater focus on identifying type 2 diabetes subtypes, their response to different therapies, and quantitation of cost-effectiveness. PMID: 20194712 [PubMed - as suppli... The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3332032 Mon, 01 Mar 2010 00:00:00 +0100 3332032 http://www.medworm.com/index.php?rid=3332031&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20194713%26dopt%3DAbstract Conclusions: Poor sleep may signal altered neuroendocrine functioning in children. The findings may offer insight into the pathways linking poor sleep with poor health. PMID: 20194713 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3332031 Mon, 01 Mar 2010 00:00:00 +0100 3332031 http://www.medworm.com/index.php?rid=3323236&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20190159%26dopt%3DAbstract Conclusions: Plasma IGF-I concentrations correlated with mean 24-h GH concentrations. This relationship is dependent exclusively on the basal GH levels. GH pulses do not determine plasma IGF-I concentrations. PMID: 20190159 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3323236 Fri, 26 Feb 2010 00:00:00 +0100 3323236 http://www.medworm.com/index.php?rid=3323235&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20190160%26dopt%3DAbstract Conclusion: These data provide indirect evidence that different factors regulate the growth of orthotopic adrenal tissue and ectopic adrenal remnants in TARTs. PMID: 20190160 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3323235 Fri, 26 Feb 2010 00:00:00 +0100 3323235 http://www.medworm.com/index.php?rid=3298794&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20173015%26dopt%3DAbstract Conclusions: Twelve weeks of endurance/strength training significantly reduced cardiac lipid content in overweight subjects and was paralleled by improved ejection fraction. This is in line with a lipotoxic action of (excess) cardiac lipids on cardiac function, although a causal relationship cannot be derived from this study. Further research is needed to clarify the clinical relevance of cardiac lipid content in the etiology of cardiovascular complications. PMID: 20173015 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3298794 Fri, 19 Feb 2010 00:00:00 +0100 3298794 http://www.medworm.com/index.php?rid=3298793&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20173016%26dopt%3DAbstract Conclusion: In aging men, polymorphisms in genes related to the pituitary-testicular endocrine function significantly influence circulating LH, testosterone, and estradiol levels, but the downstream effects may be too small to influence secondary phenotypic parameters. PMID: 20173016 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3298793 Fri, 19 Feb 2010 00:00:00 +0100 3298793 http://www.medworm.com/index.php?rid=3298792&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20173017%26dopt%3DAbstract Conclusions: Bisphosphonates are popular and effective for treatment of osteoporosis. Because they accumulate in bone and provide some residual antifracture reduction when treatment is stopped, we recommend a drug holiday after 5-10 yr of bisphosphonate treatment. The duration of treatment and length of the holiday are based on fracture risk and pharmacokinetics of the bisphosphonate used. Patients at mild risk might stop treatment after 5 yr and remain off as long as bone mineral density is stable and no fractures occur. Higher risk patients should be treated for 10 yr, have a holiday of no more than a year or two, and perhaps be on a nonbisphosphonate treatment during that time. PMID: 20173017 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Meta... The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3298792 Fri, 19 Feb 2010 00:00:00 +0100 3298792 http://www.medworm.com/index.php?rid=3298791&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20173018%26dopt%3DAbstract Conclusions: Symptomatic elderly men considered to have LOH can be differentiated on the basis of endocrine and clinical features and predisposing risk factors. Secondary hypogonadism is associated with obesity and primary hypogonadism predominately with age. Compensated hypogonadism can be considered a distinct clinical state associated with aging. Classification of LOH into different categories by combining LH with T may improve the diagnosis and management of LOH. PMID: 20173018 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3298791 Fri, 19 Feb 2010 00:00:00 +0100 3298791 http://www.medworm.com/index.php?rid=3298790&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20173019%26dopt%3DAbstract Conclusion: This new mRNA Tg quantification is a reliable method that allowed us to differentiate patients free of disease from those with metastases, and it could represent an appropriate molecular marker for the follow-up of patients with DTC, especially those with positive TgAb. PMID: 20173019 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3298790 Fri, 19 Feb 2010 00:00:00 +0100 3298790 http://www.medworm.com/index.php?rid=3298789&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20173020%26dopt%3DAbstract Conclusions: Many children with PWS had dyslipidemia and high ASP levels. GH improved fat% and high-density lipoprotein cholesterol/low-density lipoprotein cholesterol, but not ASP. High ASP levels may prevent complete normalization of fat%SDS during GH treatment but may contribute in keeping glucose and insulin levels within normal range. PMID: 20173020 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3298789 Fri, 19 Feb 2010 00:00:00 +0100 3298789 http://www.medworm.com/index.php?rid=3288548&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20164287%26dopt%3DAbstract Conclusion: This study identifies both the clinical and histological factors that relate to prolactin tumor recurrence or progression. Molecular markers give additional information for prognosis of such tumors. Altogether, our results could influence the management of patients with pituitary tumors. PMID: 20164287 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3288548 Wed, 17 Feb 2010 00:00:00 +0100 3288548 http://www.medworm.com/index.php?rid=3288547&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20164288%26dopt%3DAbstract Conclusion: CASR testing, with functional analysis, provides critical confirmatory evidence in the differential diagnosis of hypercalcemic states. PMID: 20164288 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3288547 Wed, 17 Feb 2010 00:00:00 +0100 3288547 http://www.medworm.com/index.php?rid=3288546&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20164289%26dopt%3DAbstract Conclusions: This series demonstrates a 3% occurrence of pseudotumor cerebri in children after successful surgery for CD, but the absence of the syndrome in adults. Pseudotumor cerebri manifests itself within 1 yr of surgery, often while patients are still undergoing replacement steroid therapy. A patient exhibiting signs of intracranial hypertension after surgery for CD should undergo an evaluation for pseudotumor cerebri. Recognition of the symptoms and treatment should correct and/or prevent ophthalmological sequelae. PMID: 20164289 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3288546 Wed, 17 Feb 2010 00:00:00 +0100 3288546 http://www.medworm.com/index.php?rid=3288545&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20164290%26dopt%3DAbstract Conclusions: We found that vitamin D insufficiency is associated with increased fat infiltration in muscle in healthy young women. PMID: 20164290 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3288545 Wed, 17 Feb 2010 00:00:00 +0100 3288545 http://www.medworm.com/index.php?rid=3288544&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20164291%26dopt%3DAbstract Conclusions: The relationship between adiponectin and insulin action in humans is more complex than often suggested. Further investigation of the direction of causality in this relationship, allied to studies of the cellular mechanisms involved, will be central to improving understanding of the physiological role of this enigmatic protein, and to efforts to exploit it for therapeutic benefit. PMID: 20164291 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3288544 Wed, 17 Feb 2010 00:00:00 +0100 3288544 http://www.medworm.com/index.php?rid=3288543&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20164292%26dopt%3DAbstract Conclusions: Evidence of association to several novel loci was detected in a GWAS of premenopausal EA women, and SNPs in one of these loci also provided supporting evidence in a sample of AA women. PMID: 20164292 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3288543 Wed, 17 Feb 2010 00:00:00 +0100 3288543 http://www.medworm.com/index.php?rid=3288542&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20164293%26dopt%3DAbstract Conclusion: In humans, cathepsin S is more influenced than cathepsins L and K by changes in energy balance in adipose tissue and circulation. This opens new avenues to explore whether selective inhibition of this protease could reduce cardiovascular risk and ameliorate metabolic status in obese subjects. PMID: 20164293 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3288542 Wed, 17 Feb 2010 00:00:00 +0100 3288542 http://www.medworm.com/index.php?rid=3288541&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20164294%26dopt%3DAbstract Conclusions: In aromatase-deficient men, GH response to potent provocative stimuli is impaired and is not restored by exogenous estrogens. Furthermore, a tall stature may be reached, notwithstanding the coexistence of GHD, if a prolonged time for growth is available due to a delay in bone maturation, and other growth factors different from GH (mainly insulin) promote growth. PMID: 20164294 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3288541 Wed, 17 Feb 2010 00:00:00 +0100 3288541 http://www.medworm.com/index.php?rid=3288540&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20164295%26dopt%3DAbstract Conclusions: Prevalent CVD was associated with indications of lower androgen precursors, increased aromatase activity, and higher estrogen levels in both sexes. Results might represent an endogenous response to a condition of developing atherosclerosis, rather than a causative relationship. Furthermore studies are needed. PMID: 20164295 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3288540 Wed, 17 Feb 2010 00:00:00 +0100 3288540 http://www.medworm.com/index.php?rid=3288539&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20164296%26dopt%3DAbstract Conclusion: Alendronate reduces the ability of teriparatide to increase BMD and bone turnover in women. PMID: 20164296 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3288539 Wed, 17 Feb 2010 00:00:00 +0100 3288539 http://www.medworm.com/index.php?rid=3280620&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20156921%26dopt%3DAbstract Conclusions: Our findings suggest that serum sclerostin levels are regulated by both estrogens and PTH in postmenopausal women. These findings need to be explored further in larger prospective studies. PMID: 20156921 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3280620 Mon, 15 Feb 2010 00:00:00 +0100 3280620 http://www.medworm.com/index.php?rid=3280619&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20156922%26dopt%3DAbstract Conclusions: DTC patients diagnosed after 1990 have smaller tumors with less advanced stage and a better prognosis. The question of whether this is related to the finding of tumors with a low clinical penetrance or to the anticipation of diagnosis remains to be clarified. Despite these significant differences, both advanced stage and older age still represent the most important poor prognostic factors for survival. PMID: 20156922 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3280619 Mon, 15 Feb 2010 00:00:00 +0100 3280619 http://www.medworm.com/index.php?rid=3280618&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20156923%26dopt%3DAbstract Conclusion: Serum vaspin levels have a meal-related diurnal variation, suggesting a role for vaspin in metabolic regulation. However, the reciprocal relationship between serum vaspin and insulin may negate the importance of vaspin as an physiological insulin sensitizer. PMID: 20156923 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3280618 Mon, 15 Feb 2010 00:00:00 +0100 3280618 http://www.medworm.com/index.php?rid=3280617&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20157191%26dopt%3DAbstract Conclusions: IGFBP-2 is a potential diagnostic and prognostic biomarker of CRC. LOI of IGF-II is significantly associated with poor prognosis in patients with stage IV disease. PMID: 20157191 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3280617 Mon, 15 Feb 2010 00:00:00 +0100 3280617 http://www.medworm.com/index.php?rid=3280616&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20157192%26dopt%3DAbstract Conclusions: Using a population-based sample, we confirmed that a minor subset of CH patients has transcription factor mutations, but they are rare. In our cohort, PAX8 mutations were the leading cause of such a rare condition. PMID: 20157192 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3280616 Mon, 15 Feb 2010 00:00:00 +0100 3280616 http://www.medworm.com/index.php?rid=3280615&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20157193%26dopt%3DAbstract Conclusions: Comorbid heart and liver disease were poor prognostic markers and may indicate the need for prompt adrenalectomy. The high incidence of cognitive disorders indicates a need for close developmental follow-up and parental counseling. Patients with spontaneous resolution of CS may develop adrenal insufficiency, and they require long-term monitoring. PMID: 20157193 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3280615 Mon, 15 Feb 2010 00:00:00 +0100 3280615 http://www.medworm.com/index.php?rid=3280614&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20157194%26dopt%3DAbstract Conclusion: Sex and race were associated with maturation-specific differences in cortical BMD and dimensions that were not fully explained by differences in bone length or muscle. No race or sex differences in the functional muscle bone unit were identified. PMID: 20157194 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3280614 Mon, 15 Feb 2010 00:00:00 +0100 3280614 http://www.medworm.com/index.php?rid=3280613&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20157195%26dopt%3DAbstract Conclusions: Treating XLH with phosphate and calcitriol was associated with concurrent increases in circulating FGF23 concentrations, which may diminish therapeutic effect or contribute to complications of therapy. Because it is unknown whether the degree of FGF23 elevation correlates with disease severity in XLH, further study is needed to determine whether adjusting therapy to minimize effects on FGF23 concentration is warranted. PMID: 20157195 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3280613 Mon, 15 Feb 2010 00:00:00 +0100 3280613 http://www.medworm.com/index.php?rid=3280612&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20157196%26dopt%3DAbstract Conclusion: Age, GFR, body mass index, and solid organ transplantation seem to influence FGF23 serum levels in a pediatric population. The impact of corticosteroids on FGF23 metabolism should be further investigated; further longitudinal studies will also help to better define the prognostic impact of FGF23 serum levels in pediatric CKD in terms of disease progression, cardiovascular morbidities, and bone disabilities. PMID: 20157196 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3280612 Mon, 15 Feb 2010 00:00:00 +0100 3280612 http://www.medworm.com/index.php?rid=3280611&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20157197%26dopt%3DAbstract Conclusions: Pioglitazone improves insulin resistance in T2DM in association with mobilization of fat and toxic lipid metabolites out of muscle. PMID: 20157197 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3280611 Mon, 15 Feb 2010 00:00:00 +0100 3280611 http://www.medworm.com/index.php?rid=3273272&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20150574%26dopt%3DAbstract Conclusion: A novel mutation (c.1108G>T) found in our patient results in a truncated protein (E370X). Our patient represents the first confirmed case of mosaicism in osteopathia striata with cranial sclerosis. PMID: 20150574 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3273272 Thu, 11 Feb 2010 00:00:00 +0100 3273272 http://www.medworm.com/index.php?rid=3273271&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20150575%26dopt%3DAbstract Conclusions: AR gene mutation is the most frequent cause of 46,XY DSD, with a clearly higher frequency in the complete phenotype. Mutations spread along the whole coding sequence, including exon 1. This series shows that 60% of mutations detected during the period 2002-2009 were novel. PMID: 20150575 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3273271 Thu, 11 Feb 2010 00:00:00 +0100 3273271 http://www.medworm.com/index.php?rid=3273270&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20150576%26dopt%3DAbstract Conclusion: In OLIGO adolescents, elevated serum AMH levels suggest increased antral follicle number similar to that observed in girls with PCOS. PMID: 20150576 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3273270 Thu, 11 Feb 2010 00:00:00 +0100 3273270 http://www.medworm.com/index.php?rid=3273269&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20150577%26dopt%3DAbstract Conclusions: Exercise-induced weight loss is associated with physiological and biopsychological changes toward an increased drive to eat in the fasting state. However, this seems to be balanced by an improved satiety response to a meal and improved sensitivity of the appetite control system. PMID: 20150577 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3273269 Thu, 11 Feb 2010 00:00:00 +0100 3273269 http://www.medworm.com/index.php?rid=3273268&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20150578%26dopt%3DAbstract Conclusion: In this study, we show that mtDNA content has a heritability of 35% in Dutch twins. There is no association between mtDNA content in blood and prevalent or incident T2D and related traits in our study samples. PMID: 20150578 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3273268 Thu, 11 Feb 2010 00:00:00 +0100 3273268 http://www.medworm.com/index.php?rid=3273267&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20150579%26dopt%3DAbstract Conclusion: In the Whickham Survey, there is an association between incident IHD events and IHD-related mortality with SCH over the 20 yr of follow-up. Furthermore, subsequent treatment of SCH with levothyroxine appears to attenuate IHD-related morbidity and mortality, and this may explain why some other longitudinal studies of SCH have not shown such an association; properly designed controlled trials of treatment of SCH are required to answer this question definitively. PMID: 20150579 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3273267 Thu, 11 Feb 2010 00:00:00 +0100 3273267 http://www.medworm.com/index.php?rid=3273266&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20150580%26dopt%3DAbstract Conclusions: In contrast to prototypical states of rapid bone loss (myeloma, cancer, and immobilization) in which markers of bone turnover display marked uncoupling, lactational bone loss, as assessed in this small exploratory study, is distinct, showing comparably rapid bone loss in the face of apparent osteoclast-osteoblast coupling. PMID: 20150580 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3273266 Thu, 11 Feb 2010 00:00:00 +0100 3273266 http://www.medworm.com/index.php?rid=3264091&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20147580%26dopt%3DAbstract Conclusion: The fact that obese subjects with MC4R mutations show an inverse relationship between obesity and MSNA suggests that central sympathetic outflow to the vasculature might depend on functional melanocortinergic pathways. Their dysfunction could explain reduced sympathoexcitability, lower sympathetic nerve-induced lipolysis, and the fact that blood pressure is rarely elevated in this type of obesity. PMID: 20147580 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3264091 Wed, 10 Feb 2010 00:00:00 +0100 3264091 http://www.medworm.com/index.php?rid=3264090&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20147581%26dopt%3DAbstract Conclusion: Treatment recommendations and fracture outcomes in older, predominantly osteopenic women differ substantially according to the management guideline applied. The NOGG guidelines identify only a minority of fracture cases; the NOF guidelines identify the majority of fracture cases, but at the expense of greater resource utilization. Both strategies lead to recommendations for reassurance in significant numbers of women who subsequently sustain fragility fractures. PMID: 20147581 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3264090 Wed, 10 Feb 2010 00:00:00 +0100 3264090 http://www.medworm.com/index.php?rid=3264086&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20147582%26dopt%3DAbstract Conclusions: We demonstrated that adiponectin and leptin were inversely associated with adolescent bone phenotypes but showed differential associations by gender, type of bone phenotypes, and adjustment of FM. This study also suggested that adipokines and bone phenotypes may share a common set of genes. PMID: 20147582 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3264086 Wed, 10 Feb 2010 00:00:00 +0100 3264086 http://www.medworm.com/index.php?rid=3264080&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20147583%26dopt%3DAbstract Conclusions: Our study provides an important tool to determine a shared, specific proinflammatory state of monocytes in AITD and LADA patients, enabling further research into the role of such proinflammatory cells in the failure to preserve tolerance in these conditions and of key fingerprint genes involved. PMID: 20147583 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3264080 Wed, 10 Feb 2010 00:00:00 +0100 3264080 http://www.medworm.com/index.php?rid=3258374&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20139230%26dopt%3DAbstract Conclusion: The attention that androgen abuse has received lately should be used as an opportunity to educate both athletes and the general population regarding their adverse effects. The development of sensitive detection techniques may help discourage (at least to some extent) the abuse of these compounds. Investigations are needed to identify ways to hasten the recovery of the gonadal axis in AAS users and to determine the mechanism of cardiac damage by these compounds. PMID: 20139230 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3258374 Fri, 05 Feb 2010 00:00:00 +0100 3258374 http://www.medworm.com/index.php?rid=3258373&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20139231%26dopt%3DAbstract Conclusions: The demonstration that glucocorticoid-induced muscle impairments can be unraveled by means of blood sampling and noninvasive electrophysiological tests has clinical implications for the early identification of subclinical or preclinical forms of myopathy in treated patients. PMID: 20139231 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3258373 Fri, 05 Feb 2010 00:00:00 +0100 3258373 http://www.medworm.com/index.php?rid=3258372&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20139232%26dopt%3DAbstract Conclusions: Upper quartile sCD36 is associated with elevated diabetes risk independent of age, gender, and obesity. Baseline sCD36 does not, however, predict diabetes independent of fasting glucose and insulin. sCD36 clusters with important markers of insulin resistance and MetSy that are key predictors of type 2 diabetes. PMID: 20139232 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3258372 Fri, 05 Feb 2010 00:00:00 +0100 3258372 http://www.medworm.com/index.php?rid=3258371&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20139233%26dopt%3DAbstract Conclusions: Long-term DHEA and testosterone had no significant effect on plasma lipoproteins in elderly men, but elderly women showed a lowering of the large HDL particles that may have potential adverse clinical implications. PMID: 20139233 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3258371 Fri, 05 Feb 2010 00:00:00 +0100 3258371 http://www.medworm.com/index.php?rid=3258370&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20139234%26dopt%3DAbstract Conclusions: In the United States, the cost-effectiveness of rhTSH for ablation in patients with low-risk differentiated thyroid cancer is highly dependent on potential variations in cost of rhTSH, rates of remnant ablation, time off work, and quality of life. PMID: 20139234 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3258370 Fri, 05 Feb 2010 00:00:00 +0100 3258370 http://www.medworm.com/index.php?rid=3258369&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20139235%26dopt%3DAbstract Conclusions: Although the mean total intake of vitamin D among mothers met current Nordic recommendations, 71% of women and 15% of newborns were vitamin D deficient during the pregnancy. Our results suggest that maternal vitamin D status affects bone mineral accrual during the intrauterine period and influences bone size. More efforts should be made to revise current nutrition recommendations for pregnant women that may have permanent effects on the well-being of children. PMID: 20139235 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3258369 Fri, 05 Feb 2010 00:00:00 +0100 3258369 http://www.medworm.com/index.php?rid=3247336&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20133461%26dopt%3DAbstract Conclusions: Acting via a cell surface receptor, tetrac and tetrac NP inhibit growth of h-MTC cells and associated angiogenesis in CAM and mouse xenograft models. PMID: 20133461 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3247336 Thu, 04 Feb 2010 00:00:00 +0100 3247336 http://www.medworm.com/index.php?rid=3247335&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20133462%26dopt%3DAbstract Conclusion: Post-RYGB hyperinsulinemia and hypoglycemia result entirely from altered nutrient delivery rather than generalized hyperfunction of beta-cells due to presurgical hypertrophy/hyperfunction or postsurgical nesidioblastosis. These findings support the use of GT for treatment of severe cases and have implications for surgical manipulations that may reverse/prevent this condition. PMID: 20133462 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3247335 Thu, 04 Feb 2010 00:00:00 +0100 3247335 http://www.medworm.com/index.php?rid=3247334&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20133463%26dopt%3DAbstract Conclusion: In this population of healthy adult men at the age of peak bone mass, SHBG levels were positively associated with cortical bone size, independently from sex-steroid levels. This suggests a possible independent role of SHBG in the determination of adult bone size. PMID: 20133463 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3247334 Thu, 04 Feb 2010 00:00:00 +0100 3247334 http://www.medworm.com/index.php?rid=3247333&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20133464%26dopt%3DAbstract Conclusions: FHH3 may explain the calcium homeostasis disorder in those FHH patients who do not have CASR mutations. PMID: 20133464 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3247333 Thu, 04 Feb 2010 00:00:00 +0100 3247333 http://www.medworm.com/index.php?rid=3247332&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20133465%26dopt%3DAbstract Conclusions: Studies that control for endogenous GnRH and estradiol demonstrate a direct pituitary site of estrogen negative feedback on LH and FSH responsiveness to GnRH in women. The effect of estrogen on FSH responsiveness is greater than on LH and is attenuated with aging. These studies indicate that estrogen negative feedback occurs directly at the pituitary and contributes to the differential regulation of FSH and LH secretion. PMID: 20133465 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3247332 Thu, 04 Feb 2010 00:00:00 +0100 3247332 http://www.medworm.com/index.php?rid=3247347&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20130068%26dopt%3DAbstract Conclusion: Birth weight and paternal steroid concentrations are associated with testosterone concentrations, independent from adult weight. These findings support the concept of in utero programming across the range of birth weight. PMID: 20130068 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3247347 Wed, 03 Feb 2010 00:00:00 +0100 3247347 http://www.medworm.com/index.php?rid=3247346&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20130069%26dopt%3DAbstract Conclusions: Surgical treatment and antiresorptive therapies increase BMD in mild PHPT to a similar degree, and each represents a reasonable option in a patient with mild PHPT and low BMD. Rapid bone loss does not occur in untreated mild PHPT, such that monitoring of BMD less frequently than every 1-2 yr is reasonable in individuals for whom intervention is not immediately required. PMID: 20130069 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3247346 Wed, 03 Feb 2010 00:00:00 +0100 3247346 http://www.medworm.com/index.php?rid=3247345&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20130070%26dopt%3DAbstract Conclusions: Our overall analyses showed that risk of a hip fracture was significantly lower among users of as-needed organic nitrates, when compared with users of maintenance medication. Our analyses of hip fracture risks with duration of use did not further support a beneficial effect of organic nitrates on hip fracture, although residual confounding may have masked beneficial effects. PMID: 20130070 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3247345 Wed, 03 Feb 2010 00:00:00 +0100 3247345 http://www.medworm.com/index.php?rid=3247344&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20130071%26dopt%3DAbstract Conclusion: Conserved residues of IDH1 and IDH2 or the SDHAF2 gene are not frequently mutated in pheochromocytomas and paragangliomas. The molecular basis for activation of a hypoxic response in the majority of tumors without VHL or SDH mutations remains to be defined. PMID: 20130071 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3247344 Wed, 03 Feb 2010 00:00:00 +0100 3247344 http://www.medworm.com/index.php?rid=3247343&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20130072%26dopt%3DAbstract Conclusions: The previously described associations between HPA axis activation and features of the metabolic syndrome are present among people with type 2 diabetes. Elevated plasma cortisol is also associated with a greater prevalence of ischemic heart disease, independent of conventional risk factors. Understanding the role of cortisol in the pathogenesis of ischemic heart disease merits further exploration. PMID: 20130072 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3247343 Wed, 03 Feb 2010 00:00:00 +0100 3247343 http://www.medworm.com/index.php?rid=3247342&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20130073%26dopt%3DAbstract Conclusions: Our findings demonstrate that molecular analysis of cytological specimens is feasible and that its results in combination with cytology improves the diagnostic performance of traditional cytology. PMID: 20130073 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3247342 Wed, 03 Feb 2010 00:00:00 +0100 3247342 http://www.medworm.com/index.php?rid=3247341&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20130074%26dopt%3DAbstract Conclusions: Universal screening compared with case finding did not result in a decrease in adverse outcomes. Treatment of hypothyroidism or hyperthyroidism identified by screening a low-risk group was associated with a lower rate of adverse outcomes. PMID: 20130074 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3247341 Wed, 03 Feb 2010 00:00:00 +0100 3247341 http://www.medworm.com/index.php?rid=3247340&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20130075%26dopt%3DAbstract Conclusions: WHtR represents the best predictor of cardiovascular risk and mortality, followed by WC and WHR. Our results discourage the use of the BMI. PMID: 20130075 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3247340 Wed, 03 Feb 2010 00:00:00 +0100 3247340 http://www.medworm.com/index.php?rid=3247339&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20130076%26dopt%3DAbstract Conclusions: Our study suggests imbalance between lipid oxidation and oxidative glucose metabolism in FPLD and LGMD1B patients. The observation suggests an intrinsic defect in skeletal muscle metabolism due to lamin A/C dysfunction. The metabolic FPLD phenotype likely results from this intrinsic defect combined with lipodystrophic "lipid pressure" due to decreased adipose tissue lipid storage capacity. PMID: 20130076 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3247339 Wed, 03 Feb 2010 00:00:00 +0100 3247339 http://www.medworm.com/index.php?rid=3247338&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20130077%26dopt%3DAbstract Conclusions: Aldosterone production is associated with insulin resistance in normotensive healthy subjects independent of traditional risk factors. PMID: 20130077 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3247338 Wed, 03 Feb 2010 00:00:00 +0100 3247338 http://www.medworm.com/index.php?rid=3247337&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20130078%26dopt%3DAbstract Conclusions: Although most reports do not show an association between use of dopamine agonists and valvulopathy, caution must be exercised, especially in patients requiring long-term, high-dose medication regimens. Clinicians should recommend the lowest possible doses of dopamine agonists and address the question of echocardiographic monitoring on an individual basis. PMID: 20130078 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3247337 Wed, 03 Feb 2010 00:00:00 +0100 3247337 http://www.medworm.com/index.php?rid=3247331&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20133466%26dopt%3DAbstract Authors: Adams JS, Hewison M The past decade, particularly the last 18 months, witnessed a vigorous increase in interest in vitamin D from both the lay and biomedical worlds. Much of the growing interest in vitamin D is powered by new data being extracted from the National Health and Nutrition Examination Survey (NHANES). The newest statistics demonstrate that more than 90% of the pigmented populace of the United States (Blacks, Hispanics, and Asians) now suffer from vitamin D insufficiency (25-hydroxyvitamin D <30 ng/ml), with nearly three fourths of the white population in this country also being vitamin D insufficient. This represents a near doubling of the prevalence of vitamin D insufficiency seen just 10 yr ago in the same population. This review attempts to provide some expla... The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3247331 Mon, 01 Feb 2010 00:00:00 +0100 3247331 http://www.medworm.com/index.php?rid=3247330&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20133467%26dopt%3DAbstract Authors: Wong T, Girgis CM, Ngu MC, Chen RC, Emmett L, Archer KA, Seibel MJ PMID: 20133467 [PubMed - in process] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3247330 Mon, 01 Feb 2010 00:00:00 +0100 3247330 http://www.medworm.com/index.php?rid=3247329&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20133468%26dopt%3DAbstract Authors: King KS, Whatley MA, Alexopoulos DK, Reynolds JC, Chen CC, Mattox DE, Jacobs S, Pacak K PMID: 20133468 [PubMed - in process] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3247329 Mon, 01 Feb 2010 00:00:00 +0100 3247329 http://www.medworm.com/index.php?rid=3247328&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20133469%26dopt%3DAbstract Authors: Gaylinn BD, Thorner MO PMID: 20133469 [PubMed - in process] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3247328 Mon, 01 Feb 2010 00:00:00 +0100 3247328 http://www.medworm.com/index.php?rid=3247327&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20133470%26dopt%3DAbstract Authors: Rosenbloom AL, Rivkees SA PMID: 20133470 [PubMed - in process] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3247327 Mon, 01 Feb 2010 00:00:00 +0100 3247327 http://www.medworm.com/index.php?rid=3247326&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20133471%26dopt%3DAbstract Authors: Bhasin S PMID: 20133471 [PubMed - in process] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3247326 Mon, 01 Feb 2010 00:00:00 +0100 3247326 http://www.medworm.com/index.php?rid=3232285&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20118302%26dopt%3DAbstract Conclusion: There are distinct patterns of lipid profiles associated with ethnicity regardless of the glucose levels, suggesting that ethnic-specific strategies and guidelines on risk assessment and prevention of cardiovascular disease are required. PMID: 20118302 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3232285 Fri, 29 Jan 2010 00:00:00 +0100 3232285 http://www.medworm.com/index.php?rid=3214457&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20103653%26dopt%3DAbstract Conclusions: Circulating IGFBP-5 is proteolyzed by PAPP-A2 during pregnancy, resulting in increased IGF bioavailability, which may have important consequences for the development of the fetus and/or the well-being of the mother. PMID: 20103653 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3214457 Tue, 26 Jan 2010 00:00:00 +0100 3214457 http://www.medworm.com/index.php?rid=3214456&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20103654%26dopt%3DAbstract Conclusions: Most methods to adjust BMC/BMD Z-scores for height were biased by age and/or HAZ. Adjustments using HAZ were least biased relative to HAZ and age and can be used to evaluate the effect of short or tall stature on BMC/BMD Z-scores. PMID: 20103654 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3214456 Tue, 26 Jan 2010 00:00:00 +0100 3214456 http://www.medworm.com/index.php?rid=3214455&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20103655%26dopt%3DAbstract Conclusions: Our results suggest that MS may especially influence LUTS and OAB in diabetic women, probably by compounding the effect of peripheral neuropathy. PMID: 20103655 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3214455 Tue, 26 Jan 2010 00:00:00 +0100 3214455 http://www.medworm.com/index.php?rid=3214453&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20103656%26dopt%3DAbstract Conclusion: The identified G1125A mutation results in a kinase-deficient IGF1R, which is likely to cause the phenotype of intrauterine and postnatal growth retardation. PMID: 20103656 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3214453 Tue, 26 Jan 2010 00:00:00 +0100 3214453 http://www.medworm.com/index.php?rid=3208790&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20097706%26dopt%3DAbstract Conclusions: The presence of circulating adiponectin in BSCL2/seipin patients with near absence of adipose tissue outlines the complexity of adiponectin biology. Use of circulating adiponectin might be helpful to guide the genetic investigations in BSCL. PMID: 20097706 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3208790 Fri, 22 Jan 2010 00:00:00 +0100 3208790 http://www.medworm.com/index.php?rid=3208789&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20097707%26dopt%3DAbstract Conclusion: RYGB and SG increased PYY and reduced appetite. MED failed to produce changes. Different effects occur despite similar weight loss. This suggests that the weight-loss effects of these procedures are enhanced by an increase in PYY and satiety. PMID: 20097707 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3208789 Fri, 22 Jan 2010 00:00:00 +0100 3208789 http://www.medworm.com/index.php?rid=3208788&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20097708%26dopt%3DAbstract Conclusions: Impaired beta-cell secretory capacity in islet transplantation is best explained by a low engrafted beta-cell mass and not by a deleterious effect of tacrolimus. PMID: 20097708 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3208788 Fri, 22 Jan 2010 00:00:00 +0100 3208788 http://www.medworm.com/index.php?rid=3208787&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20097709%26dopt%3DAbstract Conclusions: Intronic TCF7L2 variants may regulate alternative transcript isoforms, which in turn may have distinct physiologic roles. PMID: 20097709 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3208787 Fri, 22 Jan 2010 00:00:00 +0100 3208787 http://www.medworm.com/index.php?rid=3208786&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20097710%26dopt%3DAbstract Conclusions: The use of TSH cutoffs of 2.5 and 4.0 mU/liter, combined with thyroid antibodies, provides a clinically useful estimate of the long-term risk of hypothyroidism. PMID: 20097710 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3208786 Fri, 22 Jan 2010 00:00:00 +0100 3208786 http://www.medworm.com/index.php?rid=3208785&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20097711%26dopt%3DAbstract Conclusion: Mild hyperglycemia and NEFA intolerance to iv lipid are associated with susceptibility to lipid-induced reduction in SI and DI. PMID: 20097711 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3208785 Fri, 22 Jan 2010 00:00:00 +0100 3208785 http://www.medworm.com/index.php?rid=3208784&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20097712%26dopt%3DAbstract Conclusions: From both clinical and histopathological aspects, IgG4 thyroiditis and non-IgG4 thyroiditis were demonstrated to be distinct entities. Measuring serum IgG4 concentration provides a useful method of distinguishing IgG4 thyroiditis from non-IgG4 thyroiditis. PMID: 20097712 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3208784 Fri, 22 Jan 2010 00:00:00 +0100 3208784 http://www.medworm.com/index.php?rid=3208783&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20097713%26dopt%3DAbstract Conclusions: Decisions on GH therapy regimens should be made using both traditional (HV or DeltaHt SDS) and prediction model-derived (SR) indices of growth response. PMID: 20097713 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3208783 Fri, 22 Jan 2010 00:00:00 +0100 3208783 http://www.medworm.com/index.php?rid=3198216&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20089611%26dopt%3DAbstract Conclusions: High sensitivity and PPV suggest thoracic CT/MRI plus LOCT scans for initial imaging, with lesion confirmation by two modalities. PMID: 20089611 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3198216 Wed, 20 Jan 2010 00:00:00 +0100 3198216 http://www.medworm.com/index.php?rid=3198215&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20089612%26dopt%3DAbstract Conclusion: This is the first bone biopsy report of teriparatide response in adult HPP. In contrast to the two previously reported cases, biochemical response to teriparatide was unsustained, suggesting that response may be variable depending on the TNSALP gene mutation. PMID: 20089612 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3198215 Wed, 20 Jan 2010 00:00:00 +0100 3198215 http://www.medworm.com/index.php?rid=3198214&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20089613%26dopt%3DAbstract Authors: McLachlan RI, O'Bryan MK Intracytoplasmic sperm injection (ICSI) now provides fertility in many cases of severe idiopathic spermatogenic failure and obstructive azoospermia. Genetic causes must be sought by systematic evaluation of infertile men and affected couples informed about the implications of such diagnoses for assisted reproductive technology outcome and their potential offspring. This review discusses established and emerging genetic disorders related to fertility practice. Chromosomal anomalies are found in about 7% men with idiopathic spermatogenic failure, predominantly numerical/structural in azoospermic men and translocations/inversions in oligospermic men. Routine karyotyping of men with sperm densities less than 10 million/ml, even in the absence of other clin... The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3198214 Wed, 20 Jan 2010 00:00:00 +0100 3198214 http://www.medworm.com/index.php?rid=3198213&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20089614%26dopt%3DAbstract Conclusions: Biallelic c.6725G>A (p.R2223H) mutation causes Tg retention in the endoplasmic reticulum, resulting in dyshormonogenesis. Prolonged TSH stimulation may promote malignant transformation and development of thyroid cancer. The c.6396C>T (p.S2113L) is a novel polymorphism. PMID: 20089614 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3198213 Wed, 20 Jan 2010 00:00:00 +0100 3198213 http://www.medworm.com/index.php?rid=3198212&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20089615%26dopt%3DAbstract Conclusion: Unilateral adrenalectomy had positive impacts not only on blood pressure and biochemical parameters, but also on QOL, which was impaired preoperatively but significantly improved by 3 months postoperatively. PMID: 20089615 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3198212 Wed, 20 Jan 2010 00:00:00 +0100 3198212 http://www.medworm.com/index.php?rid=3198211&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20089616%26dopt%3DAbstract Conclusions: Our results suggest that adiponectin secretion by adipocytes in response to cytokines/chemokines and most notably in response to coculturing with ATMs differs between PCOS and control women, favoring greater suppression of adiponectin in PCOS. The mechanisms underlying these defects and the role of concurrent obesity remain to be determined. PMID: 20089616 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3198211 Wed, 20 Jan 2010 00:00:00 +0100 3198211 http://www.medworm.com/index.php?rid=3198210&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20089617%26dopt%3DAbstract Conclusions: These data suggest that 12(S)-HETE reduces insulin secretion and increases cell death in human islets. The 12-LO pathway is present in human islets, and expression is up-regulated by inflammatory cytokines. Reduction of 12-LO activity could thus provide a new therapeutic approach to protect human beta-cells from inflammatory injury. PMID: 20089617 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3198210 Wed, 20 Jan 2010 00:00:00 +0100 3198210 http://www.medworm.com/index.php?rid=3198209&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20089618%26dopt%3DAbstract Conclusion: Functional analysis results allow for the classification of novel CYP11B1 mutations as causative for classic and nonclassic 11OHD, respectively. Four partially inactivating mutations are predicted to result in nonclassic 11OHD. These findings double the number of mild CYP11B1 mutations previously described as associated with mild 11OHD. Our data are important to predict phenotypic expression and provide important information for clinical and genetic counseling in 11OHD. PMID: 20089618 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3198209 Wed, 20 Jan 2010 00:00:00 +0100 3198209 http://www.medworm.com/index.php?rid=3189994&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20080836%26dopt%3DAbstract Conclusions: Our data suggest that the natural history of the novel C634Y/Y791F double mutation carries a codon 634-like pattern of medullary thyroid carcinoma development, is associated with increased susceptibility to unusually large bilateral pheochromocytomas, and is likely more biologically active than each individual mutation. PMID: 20080836 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3189994 Fri, 15 Jan 2010 00:00:00 +0100 3189994 http://www.medworm.com/index.php?rid=3189993&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20080837%26dopt%3DAbstract Conclusion: This investigation of DITPA actions demonstrated its efficacy in reducing body weight and lowering total and low-density lipoprotein cholesterol levels. However, DITPA's adverse effects at doses used resulted in a high dropout rate and potentially dangerous skeletal actions were observed. PMID: 20080837 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3189993 Fri, 15 Jan 2010 00:00:00 +0100 3189993 http://www.medworm.com/index.php?rid=3189992&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20080838%26dopt%3DAbstract Conclusion: In communities with high prevalence of diabetes, a large percentage of patients without a diagnosis of diabetes who are admitted as in-patients have HbA1c of at least 6.5% and 7.0%. Hospital-based HbA1c testing might identify patients for whom further testing is indicated to make the diagnosis of diabetes. PMID: 20080838 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3189992 Fri, 15 Jan 2010 00:00:00 +0100 3189992 http://www.medworm.com/index.php?rid=3189991&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20080839%26dopt%3DAbstract Conclusions: Interpretation of the DDAVP test through a combination of parameters allowed effective discrimination of CD from PC, even in subjects with mild hypercortisolism. PMID: 20080839 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3189991 Fri, 15 Jan 2010 00:00:00 +0100 3189991 http://www.medworm.com/index.php?rid=3189990&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20080840%26dopt%3DAbstract Conclusions: Family history of a grandfather with hip fracture was associated with reduced aBMD and cortical bone size in 19-yr-old men, indicating that patient history of hip fracture in a grandfather could be of value when evaluating the risk of low bone mass in men. PMID: 20080840 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3189990 Fri, 15 Jan 2010 00:00:00 +0100 3189990 http://www.medworm.com/index.php?rid=3189989&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20080841%26dopt%3DAbstract Conclusions: LTA, TNF-alpha, and IL-6 genotype interactions increased MetS risk, which was further exacerbated by a low plasma polyunsaturated to saturated fat exposure, indicating important modulation of genetic risk by dietary fat exposure. PMID: 20080841 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3189989 Fri, 15 Jan 2010 00:00:00 +0100 3189989 http://www.medworm.com/index.php?rid=3189988&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20080842%26dopt%3DAbstract Conclusions: Treatments for osteoporosis with established vertebral and nonvertebral fracture efficacy reduce mortality in older, frailer individuals with osteoporosis who are at high risk of fracture. PMID: 20080842 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3189988 Fri, 15 Jan 2010 00:00:00 +0100 3189988 http://www.medworm.com/index.php?rid=3189987&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20080843%26dopt%3DAbstract Conclusion: We demonstrated 17,20-lyase deficiency due to an aberrant CytB5. Our findings thus provide evidence for an alternative etiology for this disorder. PMID: 20080843 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3189987 Fri, 15 Jan 2010 00:00:00 +0100 3189987 http://www.medworm.com/index.php?rid=3189986&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20080844%26dopt%3DAbstract Conclusion: We demonstrated a higher frequency of SF-1 overexpression and gene amplification in pediatric than in adult adrenocortical tumors, suggesting an important role of SF-1 in pediatric adrenocortical tumorigenesis. PMID: 20080844 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3189986 Fri, 15 Jan 2010 00:00:00 +0100 3189986 http://www.medworm.com/index.php?rid=3189985&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20080845%26dopt%3DAbstract Conclusions: Significant elevation of leptin can be detected in AF 2 months earlier than the appearance of symptoms; thus, it may be used as a predictive marker for preeclampsia. The increase of these antiangiogenic proteins supports the roles of inflammation and oxidative stress in pathogenesis of preeclampsia. PMID: 20080845 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3189985 Fri, 15 Jan 2010 00:00:00 +0100 3189985 http://www.medworm.com/index.php?rid=3189984&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20080846%26dopt%3DAbstract Conclusions: Thyroid dysfunction and antibodies during pregnancy seem to predict later thyroid disease. Overt hypothyroidism poses risk of diabetes. PMID: 20080846 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3189984 Fri, 15 Jan 2010 00:00:00 +0100 3189984 http://www.medworm.com/index.php?rid=3189983&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20080847%26dopt%3DAbstract Conclusions: Social isolation was more commonly reported in the whole TS cohort than in the population. Except for less pain, no significant impact on QoL attributable to GH treatment could be found, despite the mean +5.1 cm final height. PMID: 20080847 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3189983 Fri, 15 Jan 2010 00:00:00 +0100 3189983 http://www.medworm.com/index.php?rid=3189982&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20080848%26dopt%3DAbstract Conclusions: Hormonal assessment in the immediate postoperative period after TSS for CD may be misleading because delayed remission can occur in a subset of patients. Expectant management and retesting may spare some patients from unnecessary further treatment. Optimal timing to determine the need for further therapy after TSS remains to be determined. PMID: 20080848 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3189982 Fri, 15 Jan 2010 00:00:00 +0100 3189982 http://www.medworm.com/index.php?rid=3189981&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20080849%26dopt%3DAbstract Conclusion: Our findings suggest that this patient's IkappaBalpha mutation caused GH and IGF-l resistance which, in turn, contributed to his growth failure. PMID: 20080849 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3189981 Fri, 15 Jan 2010 00:00:00 +0100 3189981 http://www.medworm.com/index.php?rid=3189980&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20080850%26dopt%3DAbstract Conclusions: Acute administration of T3 in the BSD cardiac donor reverses the low T3 state and increases expression of the mRNAs encoding Kv1.5 and SERCA2a, but not ADRB1 or PLB and is not associated with any improvement in hemodynamic performance. PMID: 20080850 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3189980 Fri, 15 Jan 2010 00:00:00 +0100 3189980 http://www.medworm.com/index.php?rid=3189979&cid=s_37686_15_f&fid=37686&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D20080851%26dopt%3DAbstract Conclusions: Systemic galectin-3 is elevated in obesity and negatively correlates with glycated hemoglobin in T2D patients, pointing to a modifying function of galectin-3 in human metabolic diseases. PMID: 20080851 [PubMed - as supplied by publisher] (Source: The Journal of Clinical Endocrinology and Metabolism) The Journal of Clinical Endocrinology and Metabolism journals http://www.medworm.com/rss/comments.php?id=3189979 Fri, 15 Jan 2010 00:00:00 +0100 3189979