MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'The Journal of Dermatology' source. Wed, 08 Feb 2012 13:12:38 +0100 http://www.medworm.com/index.php?rid=5647905&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01485.x In conclusion, L‐PGDS expression may contribute to the restricted proliferation of epidermal melanocytes, but conversely its overexpression may reflect the dysregulated proliferation of melanoma cells. (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5647905 Thu, 02 Feb 2012 05:00:00 +0100 5647905 http://www.medworm.com/index.php?rid=5647904&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01487.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5647904 Thu, 02 Feb 2012 05:00:00 +0100 5647904 http://www.medworm.com/index.php?rid=5647903&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01493.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5647903 Thu, 02 Feb 2012 05:00:00 +0100 5647903 http://www.medworm.com/index.php?rid=5647902&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01494.x In this study, we performed immunohistochemical staining of 31 cases of basal cell carcinoma (BCC); 20 cases of trichoblastoma (TB), including ten cases of nodular type, eight cases of cribriform type (trichoepithelioma) and two cases of columnar type (desmoplastic trichoepithelioma); 16 cases of actinic keratosis (AK); and 10 cases each of Bowen’s disease, poroma and seborrheic keratosis. Six cases of BCC and AK were co‐lesions of both neoplasms. In normal skin tissue, Ber‐EP4 reacted positively with the secretory portion of eccrine glands and follicular germinative cells at the lower end of catagen hairs. Neoplastic cells in 97% of cases with BCC reacted positively with Ber‐EP4 in at least 5% of neoplastic cells. Those in 90% with nodular type TB and 50% with trichoepithelioma al... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5647902 Thu, 02 Feb 2012 05:00:00 +0100 5647902 http://www.medworm.com/index.php?rid=5647901&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01496.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5647901 Thu, 02 Feb 2012 05:00:00 +0100 5647901 http://www.medworm.com/index.php?rid=5647900&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01497.x AbstractCyclosporin has various effects on adipose tissue and glucose metabolism. This situation may lead to changes in serum levels of adipocyte‐derived cytokines which have influence on the pathogenesis of psoriasis. The aim of this study was to evaluate the effect of cyclosporin treatment on some adipocyte‐derived cytokines in psoriatic patients. This case–control study was performed between June 2009 and March 2010, at the Department of Dermatology of Meram School of Medicine. Serum leptin, adiponectin, resistin and ghrelin levels were assessed in 26 patients with psoriasis before and after cyclosporin treatment and body mass index‐matched 26 healthy control subjects. The adipokines levels were compared between the groups. Serum leptin, ghrelin, resistin and adiponectin levels ... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5647900 Wed, 01 Feb 2012 05:00:00 +0100 5647900 http://www.medworm.com/index.php?rid=5608921&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01451.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5608921 Thu, 19 Jan 2012 05:00:00 +0100 5608921 http://www.medworm.com/index.php?rid=5608920&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01486.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5608920 Thu, 19 Jan 2012 05:00:00 +0100 5608920 http://www.medworm.com/index.php?rid=5608919&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01491.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5608919 Thu, 19 Jan 2012 05:00:00 +0100 5608919 http://www.medworm.com/index.php?rid=5608918&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01488.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5608918 Thu, 19 Jan 2012 05:00:00 +0100 5608918 http://www.medworm.com/index.php?rid=5581868&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01477.x AbstractMalassezia globosa is a major pathogen of Malassezia folliculitis (MF) and the predominant species on human skin. The aim of this study was to clarify the differences between M. globosa and other cutaneous Malassezia species, M. restricta, M. dermatis, M. sympodialis and M. furfur. The optimum growth temperature, effects of compounds of sweat and free fatty acids on growth, and lipase activities of five cutaneous Malassezia species were determined. The growth of M. globosa was promoted strongly by the compounds of sweat and high temperature unlike that of other cutaneous Malassezia species. This result clarified that M. globosa tended to grow actively in summer conditions more than other cutaneous Malassezia species. Furthermore, M. globosa showed high lipase activity. We c... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5581868 Tue, 10 Jan 2012 05:00:00 +0100 5581868 http://www.medworm.com/index.php?rid=5581867&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01478.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5581867 Tue, 10 Jan 2012 05:00:00 +0100 5581867 http://www.medworm.com/index.php?rid=5581866&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01480.x AbstractLaser hair removal is a relatively effective method for thick hair. Despite the risk for induction of fine hair growth, application of laser for fine dark hair is sometimes inevitable. We investigate the effects of 755‐nm Alexandrite laser on fine dark facial hair and evaluate the induction rates of fine hair growth and case satisfaction. In the present study, the thickening rate of hairs (33.33%) was found to be higher than the previously published rates. However, reduction of hair density can be obtained when the laser sessions are continued. (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5581866 Tue, 10 Jan 2012 05:00:00 +0100 5581866 http://www.medworm.com/index.php?rid=5581870&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01350.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5581870 Mon, 09 Jan 2012 05:00:00 +0100 5581870 http://www.medworm.com/index.php?rid=5581869&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01472.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5581869 Mon, 09 Jan 2012 05:00:00 +0100 5581869 http://www.medworm.com/index.php?rid=5572226&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01474.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5572226 Fri, 06 Jan 2012 05:00:00 +0100 5572226 http://www.medworm.com/index.php?rid=5560231&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01468.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5560231 Thu, 05 Jan 2012 05:00:00 +0100 5560231 http://www.medworm.com/index.php?rid=5560230&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01469.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5560230 Thu, 05 Jan 2012 05:00:00 +0100 5560230 http://www.medworm.com/index.php?rid=5560234&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01464.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5560234 Wed, 04 Jan 2012 05:00:00 +0100 5560234 http://www.medworm.com/index.php?rid=5560233&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01466.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5560233 Wed, 04 Jan 2012 05:00:00 +0100 5560233 http://www.medworm.com/index.php?rid=5560232&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01467.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5560232 Wed, 04 Jan 2012 05:00:00 +0100 5560232 http://www.medworm.com/index.php?rid=5608917&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01492.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5608917 Sun, 01 Jan 2012 05:00:00 +0100 5608917 http://www.medworm.com/index.php?rid=5581865&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01482.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5581865 Sun, 01 Jan 2012 05:00:00 +0100 5581865 http://www.medworm.com/index.php?rid=5572225&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01475.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5572225 Sun, 01 Jan 2012 05:00:00 +0100 5572225 http://www.medworm.com/index.php?rid=5560229&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01473.x AbstractTreatment of chronic urticaria consists of antihistamines as the first‐line treatment. For more severe symptoms, combinations can be necessary as well as dose augmentations. The recent guidelines suggest the possibility of using omalizumab in resistant cases, but this therapy is still investigational. We treated two patients with idiopathic recurrent angioedema and 12 patients with chronic spontaneous urticaria (CSU) with omalizumab, who had not benefited from the recommended first‐line, second‐line and third‐line treatments. To evaluate the efficacy of the omalizumab treatment, urticaria activity scores (UAS) and chronic urticaria quality of life (CU‐Q2oL) scores were measured at baseline, and at the end of the first and sixth month of the therapy. The dosage and interva... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5560229 Sun, 01 Jan 2012 05:00:00 +0100 5560229 http://www.medworm.com/index.php?rid=5552366&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01476.x AbstractSpontaneous remission occurs in up to 80% of patients with limited patchy alopecia areata (AA) within 1 year. Therefore, not all patients of AA simplex/multiplex need extensive treatments, and “wait and see” is one of the choices for some patients. However, once the hair loss show progressive course, it is really difficult to manage well and may be recalcitrant to any treatment in some cases. Hair loss symptom is not life‐threatening but severely decreases quality of life. There have been two widely known guidelines for AA from the British Association of Dermatologists and the National Alopecia Areata Foundation (USA). These guidelines have been substantial and provide clues for dermatologists but needed to be updated. Recently, the Japanese Dermatological Association also ... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5552366 Sat, 31 Dec 2011 05:47:39 +0100 5552366 http://www.medworm.com/index.php?rid=5552365&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01479.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5552365 Sat, 31 Dec 2011 05:47:36 +0100 5552365 http://www.medworm.com/index.php?rid=5552364&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01498.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5552364 Sat, 31 Dec 2011 05:47:34 +0100 5552364 http://www.medworm.com/index.php?rid=5552351&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01463.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5552351 Sat, 31 Dec 2011 05:42:37 +0100 5552351 http://www.medworm.com/index.php?rid=5552363&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01452.x In conclusion, our patients showed distinctive features in clinical phenotypes, disease severity and affected body parts compared with previous reports. We also found that clinical application of systemic therapies were limited considering the severe disease state of our patients, demanding a need for more research on treatment of pediatric psoriasis. (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5552363 Thu, 29 Dec 2011 05:00:00 +0100 5552363 http://www.medworm.com/index.php?rid=5552362&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01454.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5552362 Thu, 29 Dec 2011 05:00:00 +0100 5552362 http://www.medworm.com/index.php?rid=5552361&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01456.x AbstractAxillary necrotizing fasciitis (NF) is quite rare and requires special management with respect to debridement and delayed surgical reconstruction. A 76‐year‐old man presented to our emergency department with a 2‐day history of high fever, severe left axillary pain and redness. A few hours later, he developed discoloration and hemorrhagic bulla in the axilla, and the redness enlarged on the trunk. Emergency surgical debridement was performed. The blackish necrosis in the axilla was completely excised and the erythematous areas in the chest wall were cut down to the level of the fascia. Split‐thickness skin grafts were applied during the second debridement on the 30th day of hospitalization and negative pressure wound therapy was used. Although the grafts took partially, full... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5552361 Thu, 29 Dec 2011 05:00:00 +0100 5552361 http://www.medworm.com/index.php?rid=5552360&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01457.x AbstractCarbamazepine (CBZ) is the most frequent culprit drug for severe cutaneous adverse drug reactions (ADR), such as Stevens–Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) and drug‐induced hypersensitivity syndrome (DIHS). A strong association between human leukocyte antigen (HLA)‐B*1502 and CBZ‐induced SJS/TEN has been reported in Han Chinese, Thai, Malaysian and Indian populations, but not in Caucasian or Japanese populations. Recent studies showed an association between HLA‐A*3101 and CBZ‐induced ADR in Caucasian and Japanese populations. We conducted a case–control study to determine HLA genotyping of patients with CBZ‐induced ADR in a Japanese population. Fifteen patients with CBZ‐induced ADR and 33 subjects who had taken CBZ for more than 3 months wi... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5552360 Thu, 29 Dec 2011 05:00:00 +0100 5552360 http://www.medworm.com/index.php?rid=5552359&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01465.x AbstractLong‐pulsed 755‐nm alexandrite and long‐pulsed 1064‐nm neodymium:yttrium–aluminum–garnet (Nd:YAG) lasers have been used for photorejuvenation of the face. The aim of this study was to investigate the safety and efficacy of long‐pulsed alexandrite and long‐pulsed Nd:YAG lasers for photorejuvenation in Korea. One hundred and sixteen Korean patients with photo‐aged facial skin were enrolled. Sixty‐two patients with facial pigmentation underwent long‐pulsed alexandrite laser treatment. Eleven patients that wanted to improve facial pigmentation with minimal pain had quasi‐long‐pulsed alexandrite laser treatment. Forty three patients had long‐pulsed Nd:YAG laser therapy. Outcome assessments included standard photographs and global evaluation by blinded investi... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5552359 Thu, 29 Dec 2011 05:00:00 +0100 5552359 http://www.medworm.com/index.php?rid=5552358&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01470.x AbstractBasal cell carcinoma (BCC) is the most common malignant cutaneous neoplasm, however, there have been few studies on BCC with a “rippled pattern” so far. We reviewed the 650 BCC specimens from the archives of our institution, and only one example of BCC with a rippled pattern was found. We herein report the histopathological characteristics of this case. Within the lesion, which showed the typical histopathological features of nodular BCC, there was a noticeable area composed of 10–15 basaloid aggregations, which showed the rippled pattern. The rippled pattern was characterized by alternating bands of epithelial cords of spindle‐shaped basaloid cells and mucinous spaces. Characteristically, around the rippled‐pattern area, neoplastic aggregations with a mucinous reticulate... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5552358 Thu, 29 Dec 2011 05:00:00 +0100 5552358 http://www.medworm.com/index.php?rid=5552357&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01459.x AbstractEuropean S3 Guidelines on the systemic treatment of psoriasis in 2009 propose 75% or more improvement in the Psoriasis Area and Severity Index from baseline (PASI 75) and a Dermatology Life Quality Index (DLQI) of 0 or 1 as treatment goals. However, the relationship of these two parameters is yet to be clarified. Herein, we analyzed the data pooled from two Japanese phase III clinical trials on psoriasis with infliximab to clarify the PASI response necessary to achieve a DLQI of 0 or 1. Of the 90 patients, the mean percent improvement in PASI at week 50 or 66 was 74.5%, and the PASI 75 and PASI 90 response rates were 66.7% and 46.7%, respectively; no difference in the improvement was noted among the body areas. Significant improvements in nail psoriasis were also observed. A negati... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5552357 Thu, 29 Dec 2011 05:00:00 +0100 5552357 http://www.medworm.com/index.php?rid=5552356&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01460.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5552356 Thu, 29 Dec 2011 05:00:00 +0100 5552356 http://www.medworm.com/index.php?rid=5552355&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01461.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5552355 Thu, 29 Dec 2011 05:00:00 +0100 5552355 http://www.medworm.com/index.php?rid=5552354&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01462.x AbstractProtease‐activated receptor 2 (PAR2) is a G protein‐coupled receptor which mediates a variety of functions in the skin including cutaneous inflammation. SLIGKV‐NH2, an agonist peptide for PAR2, enhanced the interleukin (IL)‐17‐induced production of two CXC chemokines, CXCL1 (GRO‐α) and CXCL8 (IL‐8), in normal human epidermal keratinocytes (NHEK) in a concentration‐dependent manner. The enhanced production of those chemokines was suppressed by a PAR2‐specific siRNA. The SLIGKV‐NH2‐induced production of both CXCL1 and CXCL8 was markedly reduced by cyclosporine A. The enhanced production of CXCL1 was suppressed by 1α, 24R‐dihydroxyvitamin D3, an active form of vitamin D3, and weakly by glucocorticoids, dexamethasone and clobetasol propionate, whereas producti... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5552354 Thu, 29 Dec 2011 05:00:00 +0100 5552354 http://www.medworm.com/index.php?rid=5552353&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2010.01144.x AbstractEruptive pseudoangiomatosis is a skin eruption characterized by millet‐sized erythema with an anemic halo appearing on exposed body areas. Insect bites, particularly mosquito bites, have been reported as one of the causes of eruptive pseudoangiomatosis. We experienced two cases of eruptive pseudoangiomatosis and the eruption was seen on the face and upper extremities of two women aged 48 and 77 years old. The two cases consented to be experimentally bitten by Culex pipiens mosquitoes and Aedes albopictus to determine if eruptive pseudoangiomatosis could be experimentally elicited by these mosquitoes. Our results showed that several minutes after a C. pipiens mosquito bite, an erythematous spot appeared on the bite site, followed by the formation of an anemic halo surrounding t... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5552353 Thu, 29 Dec 2011 05:00:00 +0100 5552353 http://www.medworm.com/index.php?rid=5552352&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01453.x AbstractXeroderma pigmentosum (XP) is an autosomal recessive inherited disease which is genetically heterogeneous. The prevalence of this genodermatosis is estimated to be 1/1 000 000 in the USA; it is more common in Japan and probably in other populations with high levels of consanguinity. The molecular diagnosis and identification of mutation in patients requires the knowledge of the causative gene by the determination of XP complementation groups. Soufir et al. have reported that XPC is the major disease‐causing gene with a recurrent mutation in the Mediterranean region. The mutation c.1643_1644delTG (p.Val548AlafsX25) represents alone 74% of all the XP probands tested and 87% in XP type C in North African patients with founder effect. We used molecular epidemiological methods in... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5552352 Thu, 29 Dec 2011 05:00:00 +0100 5552352 http://www.medworm.com/index.php?rid=5515423&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01361.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5515423 Fri, 16 Dec 2011 05:00:00 +0100 5515423 http://www.medworm.com/index.php?rid=5504925&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01417.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5504925 Wed, 14 Dec 2011 05:00:00 +0100 5504925 http://www.medworm.com/index.php?rid=5504924&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01419.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5504924 Wed, 14 Dec 2011 05:00:00 +0100 5504924 http://www.medworm.com/index.php?rid=5504923&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01420.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5504923 Wed, 14 Dec 2011 05:00:00 +0100 5504923 http://www.medworm.com/index.php?rid=5504922&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01421.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5504922 Wed, 14 Dec 2011 05:00:00 +0100 5504922 http://www.medworm.com/index.php?rid=5504921&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01424.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5504921 Wed, 14 Dec 2011 05:00:00 +0100 5504921 http://www.medworm.com/index.php?rid=5504920&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01425.x AbstractWe performed a prenatal diagnosis for 10 fetuses from nine unrelated Japanese xeroderma pigmentosum complementation group A (XP‐A) families. All parents had at least one XP‐A child (proband) with a homozygous founder mutation (IVS3‐1G>C) in the XPA gene. A genetic analysis was performed by a restriction enzyme; AlwNI fragment length polymorphism of polymerase chain reaction (PCR)‐amplified DNA, mostly from amniotic fluid (AF) and cultured cells established from AF. However, for the first family, we tried amniocentesis as well as chorionic villus sampling (CVS). Among the 10 cases, we confirmed the results of PCR‐based genetic diagnosis by post‐ultraviolet survival of amniotic cells in eight cases. Unfortunately, 6 weeks after CVS and 4 days after the amniocentesi... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5504920 Wed, 14 Dec 2011 05:00:00 +0100 5504920 http://www.medworm.com/index.php?rid=5504919&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01426.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5504919 Wed, 14 Dec 2011 05:00:00 +0100 5504919 http://www.medworm.com/index.php?rid=5504918&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01427.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5504918 Wed, 14 Dec 2011 05:00:00 +0100 5504918 http://www.medworm.com/index.php?rid=5504917&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01429.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5504917 Wed, 14 Dec 2011 05:00:00 +0100 5504917 http://www.medworm.com/index.php?rid=5504916&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01430.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5504916 Wed, 14 Dec 2011 05:00:00 +0100 5504916 http://www.medworm.com/index.php?rid=5504915&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01439.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5504915 Wed, 14 Dec 2011 05:00:00 +0100 5504915 http://www.medworm.com/index.php?rid=5504914&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01443.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5504914 Wed, 14 Dec 2011 05:00:00 +0100 5504914 http://www.medworm.com/index.php?rid=5504913&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01448.x AbstractHydroxychloroquine (HCQ) is used as the first‐line systemic treatment for severe, widespread or refractory cutaneous lupus erythematosus (CLE) in many countries. However HCQ is not an approved drug in Japan. For the establishment of HCQ therapy as the alternative treatment for CLE in Japan, we conducted a pilot study in Japanese patients with refractory CLE by administrating HCQ, and evaluated the improvements in the skin lesions using the Cutaneous Lupus Erythematosus Disease Area and Severity Index (CLASI). We administrated HCQ to seven CLE cases, including four systemic lupus erythematosus (SLE) cases. The skin lesions of the four cases improved dramatically, and their mean CLASI activity index decreased significantly following HCQ treatment. Arthralgia improved in all three c... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5504913 Wed, 14 Dec 2011 05:00:00 +0100 5504913 http://www.medworm.com/index.php?rid=5504934&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01281.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5504934 Tue, 13 Dec 2011 05:00:00 +0100 5504934 http://www.medworm.com/index.php?rid=5504933&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01337.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5504933 Tue, 13 Dec 2011 05:00:00 +0100 5504933 http://www.medworm.com/index.php?rid=5504932&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01438.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5504932 Tue, 13 Dec 2011 05:00:00 +0100 5504932 http://www.medworm.com/index.php?rid=5504931&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01441.x AbstractElevated heparanase and matrix metalloproteinase (MMP)‐9, frequently found in human cancer, is a major cause of degradation of the extracellular matrix (ECM) and basement membrane (BM), thus facilitating tumor cell migration and invasion. Although a lot of work has been done, the role of heparanase and MMP‐9 has not been delineated in skin cancer progression. The purpose of this study was to do such an exploration. To investigate the role of heparanase and MMP‐9 in cutaneous malignant melanoma (CMM) development, we performed immunohistochemical analysis to detect the alternation of these two factors in paraffin‐embedded biopsy specimens of normal skin, junctional nevi and CMM. It is interesting to note that the expression profile of heparanase and MMP‐9 was similar. Contr... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5504931 Tue, 13 Dec 2011 05:00:00 +0100 5504931 http://www.medworm.com/index.php?rid=5504930&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01444.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5504930 Tue, 13 Dec 2011 05:00:00 +0100 5504930 http://www.medworm.com/index.php?rid=5504929&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01445.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5504929 Tue, 13 Dec 2011 05:00:00 +0100 5504929 http://www.medworm.com/index.php?rid=5504928&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01446.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5504928 Tue, 13 Dec 2011 05:00:00 +0100 5504928 http://www.medworm.com/index.php?rid=5504927&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01447.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5504927 Tue, 13 Dec 2011 05:00:00 +0100 5504927 http://www.medworm.com/index.php?rid=5504926&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01449.x AbstractIncomplete or suboptimal surgical excision of basal cell carcinoma of the head and neck is a relatively frequent occurrence. Methods of preoperative assessment of tumoral margins are therefore of paramount importance. The aim of this study was to compare the preoperative evaluation of margins with digital dermoscopy and clinical definition. One hundred and 12 patients with histologically confirmed basal cell carcinoma were selected for surgical excision. Subsequently, the margin of excision was determined by either clinical (45 patients) or dermoscopic evaluation (67 patients). After pre‐surgical clinical evaluation, 22% of histological specimens of excised basal cell carcinoma showed suboptimal margins of excision. Pre‐surgical dermoscopic evaluation had only 7% suboptimal exc... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5504926 Tue, 13 Dec 2011 05:00:00 +0100 5504926 http://www.medworm.com/index.php?rid=5476614&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01263.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5476614 Mon, 05 Dec 2011 05:00:00 +0100 5476614 http://www.medworm.com/index.php?rid=5476613&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01422.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5476613 Mon, 05 Dec 2011 05:00:00 +0100 5476613 http://www.medworm.com/index.php?rid=5476612&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01371.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5476612 Mon, 05 Dec 2011 05:00:00 +0100 5476612 http://www.medworm.com/index.php?rid=5476611&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01423.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5476611 Mon, 05 Dec 2011 05:00:00 +0100 5476611 http://www.medworm.com/index.php?rid=5476610&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01428.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5476610 Mon, 05 Dec 2011 05:00:00 +0100 5476610 http://www.medworm.com/index.php?rid=5476609&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01436.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5476609 Mon, 05 Dec 2011 05:00:00 +0100 5476609 http://www.medworm.com/index.php?rid=5476608&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01437.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5476608 Mon, 05 Dec 2011 05:00:00 +0100 5476608 http://www.medworm.com/index.php?rid=5476607&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01440.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5476607 Mon, 05 Dec 2011 05:00:00 +0100 5476607 http://www.medworm.com/index.php?rid=5469065&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01333.x We present the cases of three siblings with systemic lupus erythematosus (SLE). The diagnosis was made when the sisters were of age 21, 25 and 28 years. They shared some clinical features, including typical facial rash, photosensitivity and Raynaud’s phenomenon, and tested positive for antinuclear antibodies. However, their symptoms and clinical courses varied. Human leukocyte antigen (HLA) typing revealed that DR4 and A2 were present in all three sisters, while HLA type A11, B35 and B54 were each found in two of the three sisters. The two elder sisters developed lupus glomerulonephritis 8 and 11 years after the onset of SLE. It is suggested that there are genes responsible for the onset of the disease and also unknown regulatory genes other than HLA result in different phenotypes. (... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5469065 Fri, 02 Dec 2011 05:00:00 +0100 5469065 http://www.medworm.com/index.php?rid=5469064&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01390.x In conclusion, unlike all other studies, in the present study, the two most common patterns following the parallel furrow pattern were reticular and globular, which are minor patterns. Besides the differences in pattern distribution and inherent variability in individual assessment, the age of the study group and location of nevi influence the pattern, possibly in association with race. (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5469064 Fri, 02 Dec 2011 05:00:00 +0100 5469064 http://www.medworm.com/index.php?rid=5469063&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01396.x AbstractAngiogenesis is required for physiological tissue repair processes, such as cutaneous wound healing. However, recent studies indicate that endogenous angiogenic factors may enhance photo‐induced skin alterations in response to experimental ultraviolet (UV)‐B exposure. Angiopoietin‐related growth factor (AGF), also known as angiopoietin‐like protein 6 (Angptl6), is known to promote new blood vessel formation and vascular hyperpermeability. Importantly, epidermal overexpression of Angptl6/AGF in mice promotes wound healing in the skin. However, it remains unclear whether overexpression of Angptl6/AGF facilitates tissue repair processes in response to UV‐B irradiation. To test this hypothesis, we subjected Angptl6/AGF transgenic mice to acute or chronic UV‐B exposure. Surp... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5469063 Fri, 02 Dec 2011 05:00:00 +0100 5469063 http://www.medworm.com/index.php?rid=5469062&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01402.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5469062 Fri, 02 Dec 2011 05:00:00 +0100 5469062 http://www.medworm.com/index.php?rid=5469061&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01397.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5469061 Fri, 02 Dec 2011 05:00:00 +0100 5469061 http://www.medworm.com/index.php?rid=5469060&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01316.x We report two elderly cases of CSS and review 123 cases of CSS reported in Japan between 2003 and 2010. The two patients showed typical features of CSS such as asthma, chronic sinusitis, purpura and mononeuritis multiplex. The biopsy specimens demonstrated leukocytoclastic vasculitis with infiltration of eosinophils. Both patients responded well to oral prednisolone. The age of the CSS cases we reviewed ranged from the teens to the 80s, with 47.2% of the patients aged 60 years or older. These patients tended more frequently to have complications such as gastrointestinal involvement, and a higher mortality rate. Elderly cases of CSS are not rare. Correct diagnosis at an earlier stage and careful, long‐term follow up are of particular importance in preventing a fatal outcome. (Source: Th... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5469060 Fri, 02 Dec 2011 05:00:00 +0100 5469060 http://www.medworm.com/index.php?rid=5469059&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01317.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5469059 Fri, 02 Dec 2011 05:00:00 +0100 5469059 http://www.medworm.com/index.php?rid=5469058&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01331.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5469058 Fri, 02 Dec 2011 05:00:00 +0100 5469058 http://www.medworm.com/index.php?rid=5515422&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01455.x AbstractA 32‐year‐old Taiwanese man presented to our clinic with a 6‐month history of linear hair loss in a wavy and curved pattern across the parietal and occipital scalp, resembling the distribution of Blaschko’s lines. Physical examination showed interfollicular erythema and follicular plugging without skin atrophy or sclerotic change. Histopathology revealed a lymphoplasmacytic infiltrate in the perifollicular dermis and subcutis with abundant mucin deposition, consistent with the diagnosis of lupus panniculitis. Treatment with hydroxychloroquine and local steroid injection resulted in complete hair regrowth but recurrence was noted. Linear lupus panniculitis of the scalp presenting as alopecia along Blaschko’s lines had so far been reported exclusively in five East Asians. A... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5515422 Thu, 01 Dec 2011 05:00:00 +0100 5515422 http://www.medworm.com/index.php?rid=5504912&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01450.x AbstractWe conducted a randomized controlled trial in patients with acne vulgaris with moderate to severe inflammatory lesions. The patients were assigned to the following three treatment groups: group A received monotherapy with 0.1% topical adapalene gel for 4 weeks; group B received combination therapy with 0.1% topical adapalene gel and 600 mg oral faropenem for 2 weeks followed by 0.1% topical adapalene gel alone for 2 weeks; and group C received combination therapy with 0.1% topical adapalene gel and 600 mg oral faropenem for 4 weeks. The result of the analysis indicated that the percentage reduction in inflammatory lesion counts after 2 weeks of treatment was significantly higher in groups B and C than in group A (P < 0.05). After 4 weeks of treatment, group C... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5504912 Thu, 01 Dec 2011 05:00:00 +0100 5504912 http://www.medworm.com/index.php?rid=5476606&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01442.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5476606 Thu, 01 Dec 2011 05:00:00 +0100 5476606 http://www.medworm.com/index.php?rid=5469057&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01399.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5469057 Thu, 01 Dec 2011 05:00:00 +0100 5469057 http://www.medworm.com/index.php?rid=5457822&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01313.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5457822 Thu, 01 Dec 2011 05:00:00 +0100 5457822 http://www.medworm.com/index.php?rid=5457825&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2010.01195.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5457825 Tue, 29 Nov 2011 05:00:00 +0100 5457825 http://www.medworm.com/index.php?rid=5457824&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01312.x In conclusion, both of the tumor necrosis factor‐α inhibitors demonstrated good therapeutic response similar to that in the previously reported randomized controlled trials, without any severe adverse reactions. Treatment response in scalp lesions tended to be lower in adalimumab‐treated patients, possibly because of delayed treatment onset of adalimumab. (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5457824 Tue, 29 Nov 2011 05:00:00 +0100 5457824 http://www.medworm.com/index.php?rid=5457823&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01310.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5457823 Tue, 29 Nov 2011 05:00:00 +0100 5457823 http://www.medworm.com/index.php?rid=5431777&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01412.x AbstractIchthyosis is a heterogeneous disorder characterized by abnormal skin scaling over the whole body. Autosomal recessive congenital ichthyosis (ARCI) comprises various forms, the most important of which are lamellar ichthyosis (LI) and congenital ichthyosiform erythroderma (CIE). Seven genes have been identified to be causative of ARCI, and these account for disease in 60–80% of the patients. There is notable phenotypic overlap between the major forms of ARCI, and a strong genotype–phenotype correlation has not been found. Here, we initially aimed to identify the causative gene in a large Iranian ARCI pedigree, and subsequently performed genetic analysis on four other affected pedigrees. A genotype–phenotype correlation was sought. Whole genome homozygosity mapping using high�... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5431777 Mon, 21 Nov 2011 05:00:00 +0100 5431777 http://www.medworm.com/index.php?rid=5431776&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01413.x AbstractNestin‐positive, keratin 15 (K15)‐negative multipotent hair follicle stem cells are located above the hair follicle bulge. We have termed this location the hair follicle pluripotent stem cell area. We have previously shown that transplantation of nestin‐expressing hair follicle stem cells can regenerate peripheral nerve and spinal cord injuries. In the present study, we regenerated the impinged sciatic nerve by transplanting hair follicle pluripotent stem cells. Human hair follicle stem cells were transplanted around the impinged sciatic nerve of ICR nude (nu/nu) mice. The hair follicle stem cells were transplanted between impinged sciatic nerve fragments of the mouse where they differentiated into glial fibrillary acidic protein‐positive Schwann cells and promoted the reco... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5431776 Mon, 21 Nov 2011 05:00:00 +0100 5431776 http://www.medworm.com/index.php?rid=5431775&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01414.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5431775 Mon, 21 Nov 2011 05:00:00 +0100 5431775 http://www.medworm.com/index.php?rid=5431774&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01415.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5431774 Mon, 21 Nov 2011 05:00:00 +0100 5431774 http://www.medworm.com/index.php?rid=5408144&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01432.x Abstract5‐Hydroxytryptamine 2A serotonin receptor (5‐HT2A) is associated with the contraction of vascular smooth muscle, platelet aggregation and thrombus formation and coronary artery spasms. Sarpogrelate hydrochloride (sarpogrelate) is a selective 5‐HT2A antagonist and was supposed to be effective for Raynaud’s phenomenon with collagen disease. Sarpogrelate has not been investigated regarding the effects, safety and quality of life (QOL) in patient with skin ulcers of collagen disease. Eleven patients with skin ulcers and systemic sclerosis (SSc) were administrated sarpogrelate p.o. three times a day for 3–6 months. The area (mean ± standard error) of skin ulcer at the pretreatment, and after 3 and 6 months of sarpogrelate intake was 2.1 ± 0.8, 0.2 ± 0.1 and ... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5408144 Mon, 14 Nov 2011 05:00:00 +0100 5408144 http://www.medworm.com/index.php?rid=5408143&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01433.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5408143 Mon, 14 Nov 2011 05:00:00 +0100 5408143 http://www.medworm.com/index.php?rid=5408142&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01434.x In conclusion, prevention of HBV reactivation by monitoring of HBV viral load is cost‐effective and may decrease the risk of developing drug resistance from routine anti‐HBV prophylaxis treatment. It can be considered as an alternative in psoriasis patients treated by TNF‐α inhibitors, especially in areas with a high HBV burden and in hepatitis B e‐antigen‐negative patients who have a lower risk of viral reactivation. (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5408142 Mon, 14 Nov 2011 05:00:00 +0100 5408142 http://www.medworm.com/index.php?rid=5408148&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01364.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5408148 Sun, 13 Nov 2011 05:00:00 +0100 5408148 http://www.medworm.com/index.php?rid=5408147&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01365.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5408147 Sun, 13 Nov 2011 05:00:00 +0100 5408147 http://www.medworm.com/index.php?rid=5408146&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01368.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5408146 Sun, 13 Nov 2011 05:00:00 +0100 5408146 http://www.medworm.com/index.php?rid=5408145&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01375.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5408145 Sun, 13 Nov 2011 05:00:00 +0100 5408145 http://www.medworm.com/index.php?rid=5400804&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01323.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5400804 Sat, 12 Nov 2011 05:00:00 +0100 5400804 http://www.medworm.com/index.php?rid=5400803&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01403.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5400803 Sat, 12 Nov 2011 05:00:00 +0100 5400803 http://www.medworm.com/index.php?rid=5400802&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01411.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5400802 Sat, 12 Nov 2011 05:00:00 +0100 5400802 http://www.medworm.com/index.php?rid=5386809&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01295.x This study supports the decision to use both generic and skin‐specific instruments to assess the impact of AD on QOL. (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5386809 Wed, 02 Nov 2011 04:00:00 +0100 5386809 http://www.medworm.com/index.php?rid=5386808&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01373.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5386808 Wed, 02 Nov 2011 04:00:00 +0100 5386808 http://www.medworm.com/index.php?rid=5386807&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01381.x AbstractAlthough it is a frequent disease, atopic dermatitis is poorly recognised and therefore under‐diagnosed. The aim of this study was to define and validate a convenient tool allowing presumption of atopic dermatitis for non‐dermatologists. A 20‐item questionnaire (PPAD) and an 8‐item short version (PPAD‐S) were developed in French by a board of experts, then tested on outpatients presenting with atopic dermatitis or not. Diagnosis was confirmed by a dermatologist, who measured the severity of the disease by using SCORAD. PPAD and PPAD‐S proved to be efficient tools for presumption of atopic dermatitis, but not tools for diagnosis. Scores were correlated to the severity of the disease. PPAD and PPAD‐S can be considered useful tools for orientating patients with undiagnos... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5386807 Wed, 02 Nov 2011 04:00:00 +0100 5386807 http://www.medworm.com/index.php?rid=5386806&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01384.x In this study, we investigated the efficacy and safety of tacrolimus ointment in patients with genital and extragenital lichen sclerosus. Sixteen patients with active lichen sclerosus (10 with anogenital and six with extragenital localization) were treated with topical tacrolimus ointment twice daily. The therapeutic effects were evaluated according to 3 grades: complete response (>75% improvement), partial response (25–75% improvement), or no response (<25% improvement). Applications were continued until complete disappearance or stabilization of the cutaneous lesions. In addition, we conducted telephone surveys to determine the long‐term treatment outcome and relapse rate. Objective response to therapy occurred in nine of 10 patients (90%) with anogenital and one of six patient... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5386806 Wed, 02 Nov 2011 04:00:00 +0100 5386806 http://www.medworm.com/index.php?rid=5431773&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01416.x AbstractPrimary cicatricial alopecias (PCA) are a rare group of disorders, in which the hair follicle is the main target of destructive inflammation resulting in irreversible hair loss with scarring of affected lesions. The most typical clinical manifestation of PCA is the loss of visible follicular ostia. The histopathological hallmark of a fully developed lesion is the replacement of the hair follicle structure by fibrous tissue. PCA could share similar clinical manifestations and eventually lead to “burn‐out” alopecia. Some subsets are hardly distinguishable histopathologically and the mechanisms that elicit such a destructive reaction have not been fully elucidated. Thus, the management of PCA represents one of the most challenging clinical problems for dermatologists. The aim of... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5431773 Tue, 01 Nov 2011 04:00:00 +0100 5431773 http://www.medworm.com/index.php?rid=5408141&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01435.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5408141 Tue, 01 Nov 2011 04:00:00 +0100 5408141 http://www.medworm.com/index.php?rid=5400801&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01431.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5400801 Tue, 01 Nov 2011 04:00:00 +0100 5400801 http://www.medworm.com/index.php?rid=5386805&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01395.x AbstractThe mammalian hair follicle (HF) is an active skin appendage which operates hair cycles throughout life. Recent advances in molecular genetics have led to the identification of many genes expressed in the HF. Furthermore, mutations in some of these genes have been shown to underlie congenital hair loss disorders in humans. Patients with congenital hair loss disorders can show various hair shaft anomalies, such as woolly hair and monilethrix. In the Japanese populations, most patients with congenital woolly hair/hypotrichosis possess common founder mutations in the lipase H (LIPH) gene. Identification of the causative genes for hair loss disorders directly demonstrates crucial roles of these genes in HF morphogenesis, development and/or hair growth in humans. (Source: The Journal of... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5386805 Tue, 01 Nov 2011 04:00:00 +0100 5386805 http://www.medworm.com/index.php?rid=5386824&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01398.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5386824 Mon, 31 Oct 2011 04:00:00 +0100 5386824 http://www.medworm.com/index.php?rid=5386823&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01400.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5386823 Mon, 31 Oct 2011 04:00:00 +0100 5386823 http://www.medworm.com/index.php?rid=5386822&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01401.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5386822 Mon, 31 Oct 2011 04:00:00 +0100 5386822 http://www.medworm.com/index.php?rid=5386821&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01405.x AbstractClindamycin phosphate (CDP), benzoyl peroxide (BPO) and salicylic acid (SA) are known to be effective acne therapy agents depending on their anti‐inflammatory and comedolytic properties. The purpose of this study was to investigate the efficacy and tolerability of the addition of SA treatment to CDP and BPO (SA and CDP + BPO) and compare it with CDP + BPO in patients with mild to moderate facial acne vulgaris. Forty‐nine patients were enrolled in a 12 week prospective, single‐blind, randomized, comparative clinical study. Efficacy was assessed by lesion counts, global improvement, quality of life index and measurements of skin barrier functions. Local side effects were also evaluated. Both combinations were effective in reducing total lesion (TL), inflammatory lesio... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5386821 Mon, 31 Oct 2011 04:00:00 +0100 5386821 http://www.medworm.com/index.php?rid=5386820&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01418.x AbstractThe Skindex‐16 questionnaire was recently developed as a measure of dermatological health‐related quality of life (HRQoL), including symptoms, emotions and functional aspects. Bepotastine besilate is a selective histamine H1‐receptor antagonist and a second‐generation non‐sedating antihistamine to treat various dermatological disorders. We assessed changes of the HRQoL instrument (Skindex‐16) on patients with pruritus, including those with atopic dermatitis (AD) over bepotastine treatment period. The patients’ personal assessment of the intensity of pruritus was determined using the Visual Analog Scale (VAS) for pruritus. Patients answered the Skindex‐16 at baseline and at week 4. Forty‐eight of 51 enrolled dermatological patients completed the Skindex‐16. Of th... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5386820 Mon, 31 Oct 2011 04:00:00 +0100 5386820 http://www.medworm.com/index.php?rid=5386819&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01404.x ABSTRACTA 45‐year‐old man was referred to our hospital with a history of multiple erythematous skin lesions of several months’ duration. Blood examination revealed extreme hypoproteinemia and hypoalbuminemia, as well as the presence of antinuclear antibodies. A skin biopsy specimen showed liquefaction degeneration at the dermoepidermal junction and dense lymphocyte and neutrophil infiltration around the vessels and appendages in the upper and middle dermis. Chest X‐ray and computed tomography showed a pleural effusion and thoracic paracentesis revealed a mononuclear cell‐dominant cell infiltration, suggestive of serositis. Technetium‐99m (99mTc)‐labeled human serum albumin scintigraphy and α1‐antitrypsin clearance revealed protein leakage along the digestive tracts from th... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5386819 Mon, 31 Oct 2011 04:00:00 +0100 5386819 http://www.medworm.com/index.php?rid=5386818&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01407.x We describe a 14‐year‐old boy and 71‐year‐old man with nephrogenic systemic fibrosis and review the Japanese cases documented thus far. In Japan, there are only 10 cases definitely associated with gadolinium, whereas over 500 cases have been recorded worldwide. We found a remarkable difference in clinical signs among Japanese cases. Some cases showed keratotic papules or plaques on the extremities. This group tended to develop symptoms after a shorter interval following gadolinium exposure. The remainder of the cases presented glossy and smooth surfaces, with symptoms tending to develop after a longer interval following their last gadolinium exposure. The discrepancies between the actual and the estimated number of patients, and the various clinical manifestations can be explained ... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5386818 Mon, 31 Oct 2011 04:00:00 +0100 5386818 http://www.medworm.com/index.php?rid=5386817&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01406.x This study was done to find out differences in stratum corneum ceramides between SS and non‐SS groups. Fifty individuals (20 with SS and 30 with non‐SS) were recruited. Lactic acid sting test (LAST) was performed on the left cheek. On six sites including the right cheek, arm, thigh, leg, back and palm, transepidermal water loss (TEWL) and erythema index (EI) were measured. On the above six sites, stratum corneum sheets were obtained by stripping with cyanoacrylate resin and stratum corneum lipids were extracted, then, analyzed by high‐performance liquid chromatography electrospray ionization mass spectrometry. LAST scores were higher in the SS group, but not statistically significant. There were no differences in TEWL and EI values between the two groups. The mean value of the quanti... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5386817 Mon, 31 Oct 2011 04:00:00 +0100 5386817 http://www.medworm.com/index.php?rid=5386816&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01410.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5386816 Mon, 31 Oct 2011 04:00:00 +0100 5386816 http://www.medworm.com/index.php?rid=5386815&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01408.x This article reviews the association of psoriasis and metabolic syndrome in terms of adipocytokines and evaluates the role of biologic agents in the treatment of psoriasis. (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5386815 Mon, 31 Oct 2011 04:00:00 +0100 5386815 http://www.medworm.com/index.php?rid=5386814&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01250.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5386814 Mon, 31 Oct 2011 04:00:00 +0100 5386814 http://www.medworm.com/index.php?rid=5386813&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01272.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5386813 Mon, 31 Oct 2011 04:00:00 +0100 5386813 http://www.medworm.com/index.php?rid=5386812&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01282.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5386812 Mon, 31 Oct 2011 04:00:00 +0100 5386812 http://www.medworm.com/index.php?rid=5386811&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01283.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5386811 Mon, 31 Oct 2011 04:00:00 +0100 5386811 http://www.medworm.com/index.php?rid=5386810&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01288.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5386810 Mon, 31 Oct 2011 04:00:00 +0100 5386810 http://www.medworm.com/index.php?rid=5360463&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01294.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5360463 Mon, 31 Oct 2011 03:33:11 +0100 5360463 http://www.medworm.com/index.php?rid=5360465&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01291.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5360465 Thu, 27 Oct 2011 04:00:00 +0100 5360465 http://www.medworm.com/index.php?rid=5360464&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01292.x The objective of this study was to assess the long‐term outcomes and complications of PDT therapy of PWS in Chinese patients retrospectively. Patients with PWS who had received PDT therapy in a 5‐year period were reviewed. 642 patients and a total of 3066 treatment sessions had been performed with an average of 2.6–8.2 sessions. Over 5% of patients had complete clearing, while 70% of patients had more than 25% of clearing. More than one‐quarter of patients (29.8%) experienced a clearing of more than 50%. Ten percent of patients experienced complications (1.4% blistering, 1.2% hypopigmentation, 4.3% hyperpigmentation, 2.2% scabbing, <0.7% prolonged blistering that persisted for >2 months, 0.4% eczema dermatitis, 0.6% photoallergy). Sex, age, number of treatment sessions, avera... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5360464 Thu, 27 Oct 2011 04:00:00 +0100 5360464 http://www.medworm.com/index.php?rid=5572227&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01387.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5572227 Thu, 20 Oct 2011 04:00:00 +0100 5572227 http://www.medworm.com/index.php?rid=5335880&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01387.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5335880 Thu, 20 Oct 2011 04:00:00 +0100 5335880 http://www.medworm.com/index.php?rid=5335879&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01388.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5335879 Thu, 20 Oct 2011 04:00:00 +0100 5335879 http://www.medworm.com/index.php?rid=5335878&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01389.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5335878 Thu, 20 Oct 2011 04:00:00 +0100 5335878 http://www.medworm.com/index.php?rid=5335877&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01392.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5335877 Thu, 20 Oct 2011 04:00:00 +0100 5335877 http://www.medworm.com/index.php?rid=5335886&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01284.x This report shows that the USA300 clone can manifest severe skin infections such as furuncles and carbuncles even in healthy persons, which require drainage and i.v. treatment, and suggests that the clone can spread in hospital settings worldwide. (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5335886 Tue, 18 Oct 2011 04:00:00 +0100 5335886 http://www.medworm.com/index.php?rid=5335885&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01293.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5335885 Tue, 18 Oct 2011 04:00:00 +0100 5335885 http://www.medworm.com/index.php?rid=5335884&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01279.x In this study, we treated two patients with refractory GPP by using GCAP. Patient 1, a 68‐year‐old woman who had liver cirrhosis, underwent seven GCAP sessions. Patient 2, a 26‐year‐old woman who had systemic lupus erythematosus and had been treated with systemic corticosteroids, underwent eight GCAP sessions. In both patients, GCAP resulted in an immediate improvement in skin lesions and fever reduction, without any adverse effects. We suggest that GCAP is an effective therapy for refractory GPP. (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5335884 Tue, 18 Oct 2011 04:00:00 +0100 5335884 http://www.medworm.com/index.php?rid=5335883&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01280.x This study showed the efficacy and safety of the combination therapy of nadifloxacin cream with adapalene gel for the inflammatory acne. (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5335883 Tue, 18 Oct 2011 04:00:00 +0100 5335883 http://www.medworm.com/index.php?rid=5335882&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01287.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5335882 Tue, 18 Oct 2011 04:00:00 +0100 5335882 http://www.medworm.com/index.php?rid=5335881&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01290.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5335881 Tue, 18 Oct 2011 04:00:00 +0100 5335881 http://www.medworm.com/index.php?rid=5304488&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01278.x AbstractTo avoid complications of high dose corticosteroid, pemphigus patients are usually co‐treated with other immunosuppressive agents. Liver enzyme abnormality occurs commonly during treatment and occasionally causes discontinuation of drugs. To assess the rate of therapy‐induced hepatotoxicity in patients with immunobullous diseases, we conducted a study of 250 pemphigus patients under immunosuppressive therapy prospectively. Aspartate aminotransferase (AST), alanine aminotransferase (ALT) and alkaline phosphatase (ALP) plasma levels were recorded before the start of treatment and every week under treatment (up to 3 weeks). Hepatotoxicity was defined as the rise in the ALT plasma levels to greater than twice the upper normal limit. Approximately 81% of patients received predniso... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5304488 Mon, 10 Oct 2011 04:00:00 +0100 5304488 http://www.medworm.com/index.php?rid=5304487&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01372.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5304487 Mon, 10 Oct 2011 04:00:00 +0100 5304487 http://www.medworm.com/index.php?rid=5304486&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01378.x This study represents data collected at a single institution. Many patients did not receive follow‐up examination. In Japanese men with AGA, oral finasteride used in the long‐term study maintained progressive hair regrowth without recognized side‐effect. (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5304486 Mon, 10 Oct 2011 04:00:00 +0100 5304486 http://www.medworm.com/index.php?rid=5285797&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01356.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5285797 Wed, 05 Oct 2011 04:00:00 +0100 5285797 http://www.medworm.com/index.php?rid=5285796&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01357.x AbstractThe diagnosis of systemic sclerosis (SSc) is often difficult. The purpose of the present study was to find the distribution of nail fold capillary abnormality in SSc. Sixty‐two patients with SSc (male : female = 7:55, age 21–86 years, mean 60.1) admitted to the outpatient clinics were studied. Eighteen age‐ and sex‐matched normal subjects, 28 patients with systemic lupus erythematosus (SLE) and 10 with dermatomyositis (DM) were also studied. Nail fold capillary loops were observed under immersion oil at a magnification of ×40 with a light microscope. Dilated capillaries, nail fold bleeding and avascular areas were found by dermoscopic observation. The distribution of dilated capillaries, nail fold bleeding and avascular areas in normal controls showed in one (5.6... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5285796 Wed, 05 Oct 2011 04:00:00 +0100 5285796 http://www.medworm.com/index.php?rid=5285795&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01366.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5285795 Wed, 05 Oct 2011 04:00:00 +0100 5285795 http://www.medworm.com/index.php?rid=5285807&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01252.x AbstractAcanthosis nigricans is a rare mucocutaneous disorder of unknown etiology that manifests as hyperpigmented velvety plaques, most often on intertriginous areas such as the neck and axillae as well as on mucosal sites such as the oral cavity. The disorder presents either as a paraneoplastic manifestation of an underlying malignancy, especially gastrointestinal adenocarcinomas or in association with obesity, administration of drugs or endocrinopathies, most commonly insulin‐resistant diabetes mellitus. In the present article, a case of acanthosis nigricans with oral and cutaneous manifestations in a male patient with chronic hepatitis B infection is described. To the best of our knowledge, this is the first case of benign oral acanthosis nigricans associated with chronic hepatitis B... The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5285807 Tue, 04 Oct 2011 04:00:00 +0100 5285807 http://www.medworm.com/index.php?rid=5285806&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01300.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5285806 Tue, 04 Oct 2011 04:00:00 +0100 5285806 http://www.medworm.com/index.php?rid=5285805&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01380.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5285805 Tue, 04 Oct 2011 04:00:00 +0100 5285805 http://www.medworm.com/index.php?rid=5285804&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01383.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5285804 Tue, 04 Oct 2011 04:00:00 +0100 5285804 http://www.medworm.com/index.php?rid=5285803&cid=s_31730_12_f&fid=31730&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1346-8138.2011.01363.x (Source: The Journal of Dermatology) The Journal of Dermatology journals http://www.medworm.com/rss/comments.php?id=5285803 Tue, 04 Oct 2011 04:00:00 +0100 5285803