The Rockefeller University Newswire via MedWorm.com MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'The Rockefeller University Newswire' source. Sat, 20 Mar 2010 16:03:01 +0100 Scientists pinpoint source of recurrent yeast infections in autoimmune syndrome http://www.medworm.com/index.php?rid=3353711&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D1045 It turns out that the immune system can create its own infections. Scientists now report that the immune-fighting proteins that keep yeast in check in healthy immune systems are under siege in patients with a rare autoimmune disorder known as APS-1. By pinpointing the cause of candidiasis in these patients, the finding paves the way for treating these fungal infections with drugs that are already out in the market. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=3353711 Thu, 11 Mar 2010 14:15:00 +0100 3353711 Scientists track variant of gene-regulating protein in embryonic stem cells http://www.medworm.com/index.php?rid=3349682&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D1044 The path to fully developed cells from embryonic stem cells requires that the right genes are turned on and off at the right times. New research from Rockefeller University shows that tiny variations between gene-regulating histone proteins play an important role in determining how and when genes are read. The finding shows that each region of the genome may be even more specialized than previously expected and may open a new avenue of investigation regarding the mysterious causes of the human genetic disease known as ATR-X syndrome. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=3349682 Wed, 10 Mar 2010 13:00:00 +0100 3349682 Research identifies gene that changes the brain’s response to stress http://www.medworm.com/index.php?rid=3349683&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D1043 Brains change. They change throughout life, responding to developmental but also environmental cues, like stress. Scientists know of several important proteins that play a role in what brains do with new experience. Now they have identified one, brain-derived neurotrophic factor, which must be present at a certain level to enable the brain’s “adaptive plasticity,” particularly in response to stress. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=3349683 Tue, 09 Mar 2010 16:00:00 +0100 3349683 Imaging studies reveal order in programmed cell death http://www.medworm.com/index.php?rid=3310805&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D1037 In order to thrive, the human body orchestrates a mass suicide of about 10 billion potentially dangerous cells a day. New research takes a closer look at programmed cell death — called apoptosis — and finds order in this process, once thought to be an erratically timed, sudden collapse. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=3310805 Thu, 25 Feb 2010 19:00:00 +0100 3310805 Mouse model reveals a cause of ADHD http://www.medworm.com/index.php?rid=3297777&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D1038 New research in a mouse model of attention deficit/hyperactivity disorder suggests that the root of the psychiatric disorder might be the over-activity of a protein that regulates the brain’s reward-motivation system. The work suggests a path toward new treatments for symptoms including inattentiveness, over-activity and impulsivity. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=3297777 Mon, 22 Feb 2010 17:45:00 +0100 3297777 Scientists crash test DNA’s replication machinery http://www.medworm.com/index.php?rid=3258198&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D1036 Important molecular machines routinely crash into one another while plying their trades on DNA. New research shows that the enzymes that copy DNA before cell division, called replisomes, are the kings of this road, kicking aside machines that are performing less critical tasks, such as transcribing instructions for proteins. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=3258198 Tue, 09 Feb 2010 19:45:00 +0100 3258198 Research identifies gene with likely role in premenstrual disorder http://www.medworm.com/index.php?rid=3258199&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D1034 Some women are especially sensitive to the natural flux of hormones in the menstrual cycle. New research points to a gene that likely influences how women respond to swings in estrogen levels and could help diagnose and treat premenstrual dysphoric disorder, a condition marked by extreme mood swings and irritability. The work also provides insight into the historically understudied area of medically relevant differences between men and women. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=3258199 Tue, 09 Feb 2010 17:00:00 +0100 3258199 Leaf veins inspire a new model for distribution networks http://www.medworm.com/index.php?rid=3253887&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D1029 Following the straight and narrow may be good moral advice, but it’s not a great design principle for a distribution network. In new research, a team of biophysicists describe a complex netting of interconnected looping veins that evolution devised to distribute water in leaves. The work, which bucks decades of thinking, may compel engineers to revisit some common assumptions that have informed the building of many human-built distribution networks. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=3253887 Tue, 09 Feb 2010 14:00:00 +0100 3253887 By tracking water molecules, physicists hope to unlock secrets of life http://www.medworm.com/index.php?rid=3246525&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D1031 Compared to any other liquid on Earth, water behaves in strange and unexpected ways, yet its unusual properties enable and protect life as we know it. By tracking individual water molecules in a “supercooled” state, scientists find what explains one of water’s most notable and life-saving features: its astounding capacity to resist gaining or losing heat. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=3246525 Fri, 05 Feb 2010 22:00:00 +0100 3246525 Newly engineered enzyme is a powerful staph antibiotic http://www.medworm.com/index.php?rid=3246526&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D1030 In the past decade, methicillin-resistant Staphylococcus aureus, or MRSA, has ushered in a new era in the fight between man and bug. By harnessing the power of nature’s own antibiotics, scientists have engineered an enzyme known as a lysin that not only kills MRSA in mice but also works synergistically with antibiotics that were once powerless against the formidable organism. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=3246526 Fri, 05 Feb 2010 19:30:00 +0100 3246526 Brain arousal heightens sexual activity in male mice http://www.medworm.com/index.php?rid=3215774&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D1025 Ever since the dawn of time, teenage boys have been defined by their sexual urges. Stereotype or not, the same fate has now befallen male mice. In new research that harkens back to those awkward high school moments and uncomfortable coming-of-age memories, scientists now show that male mice genetically selected for high levels of nervous energy act like sex-crazed teenage boys: highly motivated, but awkward and inefficient. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=3215774 Wed, 27 Jan 2010 18:45:00 +0100 3215774 Researchers track evolution and spread of drug-resistant bacteria across hospitals and continents http://www.medworm.com/index.php?rid=3200014&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D1024 Using high resolution genome sequencing, scientists have tracked a deadly strain of multidrug-resistant Staphylococcus aureus as it traveled between South America, Europe and Southeast Asia. The new technique provides an unprecedented view of how MRSA evolved over decades and across entire continents, as well as on the short timescale of a few weeks within a hospital in Thailand. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=3200014 Fri, 22 Jan 2010 14:45:00 +0100 3200014 First evidence that the brain’s native dendritic cells can muster an immune response http://www.medworm.com/index.php?rid=3200015&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D1022 Since their initial discovery in 1973, dendritic cells, the sentinels of the immune system, have turned up in a number of places other than the immune organs. They stand guard in the heart, for instance, and in 2008, the first population native to the brain was identified. New research shows that dendritic cells are not only present in the brain, but active, too. They confront foreign substances and seem to form a barrier between healthy and stricken brain tissue following a stroke. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=3200015 Thu, 21 Jan 2010 15:00:00 +0100 3200015 Clinical Trial to explore link between vitamin D and cholesterol http://www.medworm.com/index.php?rid=3188545&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D1023 An unusual finding in previous studies of vitamin D-deficient patients has prompted a new clinical study at The Rockefeller University Hospital. Investigator Manish Ponda aims to discover if there is a causative relationship between vitamin D supplementation and elevated levels of small LDL cholesterol. The hospital is currently recruiting subjects for the study. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=3188545 Wed, 20 Jan 2010 15:45:00 +0100 3188545 Loss of epigenetic regulators causes mental retardation http://www.medworm.com/index.php?rid=3156040&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D1021 New findings, published in recent issues of Neuron and Science, indicate that malfunction of a protein complex that normally suppresses gene activation causes mental retardation in mice and humans and may even play a role in promoting susceptibility to drug addiction. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=3156040 Fri, 08 Jan 2010 21:15:00 +0100 3156040 Loosely coiled DNA helps trypanosomes make their escape http://www.medworm.com/index.php?rid=3156041&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D1020 Some animals use camouflage to outsmart their prey; others use mimicry or fake their own death. But Trypanosoma brucei, the wily parasite that causes African sleeping sickness, is the only organism we know of that can change its molecular identity on command to escape the grip of the human immune system. New research reveals a key discovery that has eluded scientists for decades: To avoid capture, trypanosomes must strategically uncoil their DNA. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=3156041 Fri, 08 Jan 2010 18:30:00 +0100 3156041 DNA ‘barcoding’ reveals 95 species of life in NYC homes, students show http://www.medworm.com/index.php?rid=3124244&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D1017 Armed with the latest high-tech DNA analysis techniques, two New York City high school students examined every nook and cranny of their homes and were astonished to discover a veritable zoo of 95 animal species surrounding them, in everything from fridges to furniture. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=3124244 Mon, 28 Dec 2009 14:00:00 +0100 3124244 Genomic differences identified in common skin diseases http://www.medworm.com/index.php?rid=3118347&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D1014 If you have dry skin, wet it, if wet skin, dry it. This has been a general rule of dermatology for centuries, but scientists are working to develop more precise treatments for the dozen-plus inflammatory skin diseases that afflict people. New research details the fine genetic and immunological differences between two of the most common skin diseases, psoriasis and atopic eczema, presenting a new way to classify the disorders as well as possible novel therapeutics. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=3118347 Wed, 23 Dec 2009 20:30:00 +0100 3118347 Scientists visualize how a vital hepatitis C virus protein moves along its nucleic acid substrate http://www.medworm.com/index.php?rid=3118348&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D1016 In a series of three snapshots that recapitulate the coordinated actions, scientists reveal how a protein essential for the replication of the hepatitis C virus moves along its nucleic acid substrate. The finding illustrates the nucleotide-dependent changes of interactions between the protein, known as NS3, and DNA, work that suggests some of the most feasible strategies to date to block the action of this largely unexplored drug target. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=3118348 Wed, 23 Dec 2009 19:30:00 +0100 3118348 Titia de Lange awarded grant, named American Cancer Society Research Professor http://www.medworm.com/index.php?rid=3118349&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D1015 The head of Rockefeller University’s Laboratory of Cell Biology and Genetics has received a $400,000 grant from the American Cancer Society and has been named an American Cancer Society Research Professor. The five-year grant, which is effective January 1, 2010, will fund de Lange’s continuing research on telomeres, the strings of extra DNA that cap and protect the ends of chromosomes through numerous cycles of cell division. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=3118349 Wed, 23 Dec 2009 15:45:00 +0100 3118349 Rockefeller University receives nearly $27 million in ARRA grants http://www.medworm.com/index.php?rid=3104486&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D1004 Investigators at The Rockefeller University have so far been awarded 41 federal grants and supplemental awards through the American Recovery and Reinvestment Act of 2009 (ARRA) — the so-called “stimulus” legislation passed by Congress last winter. Ranging in size from about $5,000 to nearly $4.6 million, the grants will fund new and ongoing projects in biomedical and clinical research and training. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=3104486 Fri, 18 Dec 2009 16:15:00 +0100 3104486 Mutation leads to new and severe form of bacterial disease http://www.medworm.com/index.php?rid=3099880&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D1013 Everybody gets sick, but how sick you get is in your genes. New research now reveals a mutation on a gene that makes children susceptible to a severe form of mycobacterial disease. The work not only supports a controversial idea that certain genes evolved to combat specific bacteria but also reveals new mechanistic details of how the immune system fights off one of the planet’s fiercest pathogens. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=3099880 Thu, 17 Dec 2009 16:15:00 +0100 3099880 Bacterial protein mimics its host to disable a key enzyme http://www.medworm.com/index.php?rid=3078586&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D1011 Bacteria use all sorts of cunning to trick hosts into doing their bidding. One con in their bag of tricks: the molecular mimic. In this ruse, bacteria or their agents look for all purposes like some native molecule in a cell, but then do not behave accordingly. Working with H. pylori, the bacterium responsible for gastric ulcers and cancer, researchers have revealed one way bacteria pull this off, deciphering the structure of a piece of CagA, a bacterial protein that impersonates a human protein in order to disable a key enzyme. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=3078586 Thu, 10 Dec 2009 20:45:00 +0100 3078586 New molecule identified in DNA damage response http://www.medworm.com/index.php?rid=3070527&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D1007 Evolution places the highest premium on reproduction, natural selection’s only standard for biological success. In the case of replicating cells, life spares no expense to ensure that the offspring is a faithful copy of the parent. Researchers have identified a new player in this elaborate system of quality control, a gene whose mutation can cause a rare but lethal disease. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=3070527 Tue, 08 Dec 2009 16:15:00 +0100 3070527 Rockefeller postdoc wins GE & Science Prize http://www.medworm.com/index.php?rid=3059202&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D1009 Michael Crickmore has been named Grand Prize winner in the essay competition, which recognizes outstanding graduate students in molecular biology. Crickmore’s essay, titled “The Molecular Basis of Size Differences,” comes with $25,000 and publication in Science. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=3059202 Fri, 04 Dec 2009 18:15:00 +0100 3059202 Elusive protein points to mechanism behind hearing loss http://www.medworm.com/index.php?rid=3059203&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D1008 A serendipitous discovery in zebra fish larvae born deaf has helped narrow down the function of an elusive protein necessary for hearing and balance. In addition to unveiling a potential target for therapy, the work suggests that hearing loss may arise from a faulty pathway that translates sound into electrical nerve impulses the brain can understand. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=3059203 Fri, 04 Dec 2009 18:00:00 +0100 3059203 Rockefeller human embryonic stem cell lines now available through NIH registry http://www.medworm.com/index.php?rid=3051597&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D1005 Two human embryonic stem cell lines, derived using private funds, are among the first 13 human embryonic stem cell lines for use in NIH-funded research under the NIH Guidelines for Human Stem Cell Research adopted in July 2009. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=3051597 Wed, 02 Dec 2009 21:45:00 +0100 3051597 Acute stress leaves epigenetic marks on the hippocampus http://www.medworm.com/index.php?rid=3022422&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D1002 Scientists are learning that the dynamic regulation of genes — as much as the genes themselves — shapes the fate of organisms. Now the discovery of a new epigenetic mechanism regulating genes in the brain under stress is helping change the way scientists think about psychiatric disorders and could open new avenues to treatment. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=3022422 Mon, 23 Nov 2009 16:00:00 +0100 3022422 Multitasking may be Achilles heel for hepatitis C http://www.medworm.com/index.php?rid=3014963&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D1001 Hepatitis C, a formidable virus that affects 130 million people worldwide, is nursing some pretty impressive bruises. By knocking out sections and subsections of one of its proteins, scientists reveal weak spots in the virus’s armor and gain new momentum for developing drug targets for sufferers of the disease. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=3014963 Thu, 19 Nov 2009 16:30:00 +0100 3014963 Scientists identify DNA that regulates antibody production http://www.medworm.com/index.php?rid=3011646&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D1000 When foreign invaders trip the immune system’s alarm, antibodies need to be specially sculpted to attack them head on. New research now shows that gene segments called enhancers control the reshuffling of antibody genes that makes such a precise and coordinated attack possible. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=3011646 Thu, 19 Nov 2009 14:30:00 +0100 3011646 Shaham and Chalasani named winners of 2009 Blavatnik Awards http://www.medworm.com/index.php?rid=3003175&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D999 Associate Professor Shai Shaham and Postdoctoral Fellow Sreekanth H. Chalasani, who were named finalists in the third annual competition in September, were honored last night with six other winners at the New York Academy of Sciences’ Science and the City Gala. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=3003175 Tue, 17 Nov 2009 17:00:00 +0100 3003175 Imaging study shows HIV particles assembling around its genome http://www.medworm.com/index.php?rid=2998958&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D998 The genesis of one the planet’s most lethal viruses, HIV, has been caught on tape. New imaging experiments show individual HIV genomes — strands of RNA — docking on the inner membrane of an infected cell wall as they are ensconced by HIV structural proteins. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2998958 Mon, 16 Nov 2009 19:30:00 +0100 2998958 Two proteins act as molecular tailors in DNA repair http://www.medworm.com/index.php?rid=2988344&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D997 On average, our cells encounter a very lethal form of DNA damage 10 times a day. Lucky for us, we have the capacity to repair each and every one of them. New research now reveals exactly how two well-known proteins are involved in the process, a finding that not only helps shed light on cancer but also on how our cells maintain the integrity of our genome. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2988344 Thu, 12 Nov 2009 20:15:00 +0100 2988344 High fat diet increases inflammation in the mouse colon http://www.medworm.com/index.php?rid=2984325&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D996 In mice fed a diet high in fat and low in fiber, vitamin D and calcium — the so-called Western diet — expression of a series of genes collectively associated with immune and inflammatory responses was altered. The findings show that a Western diet induces oxidative stress and alters immune responses in the colon of mice long before tumors occur. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2984325 Wed, 11 Nov 2009 22:15:00 +0100 2984325 Rockefeller joins first national research study recruitment registry http://www.medworm.com/index.php?rid=2980553&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D995 Rockefeller University has joined more than 50 U.S. research institutions in making information about its clinical research trials available on ResearchMatch, the country’s first registry for recruiting research participants. The secure Web site offers a free and safe way for volunteers to connect with thousands of researchers who are conducting research on a wide range of diseases. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2980553 Tue, 10 Nov 2009 22:00:00 +0100 2980553 Scientists reveal a new mechanism that increases atherosclerosis in mice http://www.medworm.com/index.php?rid=2962580&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D993 For all the good it does, a liver protein that senses and gets rid of drugs and pollutants from our body has a downside. For the first time, it has been shown that when it is chronically activated, the protein, called PXR, rejiggers how cholesterol is processed in the liver and increases the risk of developing atherosclerosis. The work has direct clinical consequences to patients under long-term treatment of PXR-activating drugs, including several antibiotic and anti-cancer medications — and your daily latte. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2962580 Wed, 04 Nov 2009 15:15:00 +0100 2962580 Immune system uses a “leash” to restrict HIV’s spread http://www.medworm.com/index.php?rid=2958301&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D991 New research shows how an antiviral protein, tetherin, lashes newborn viral particles to infected cells, slowing the spread of infection. Understanding how this immune system defense works against HIV, Ebola and other deadly viruses could lead to better antiviral therapies. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2958301 Tue, 03 Nov 2009 21:00:00 +0100 2958301 Disrupting sleep causes problems for the body and brain http://www.medworm.com/index.php?rid=2926777&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D988 Modern life disrupts our natural sleep cycles with shift-work, jet lag and ubiquitous electric lighting, among other things. New research in mice suggests that the resulting disturbance of nature’s circadian rhythms could have major effects on the body and brain, from a slowing of metabolism to impaired thinking and poor impulse control. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2926777 Mon, 26 Oct 2009 15:30:00 +0100 2926777 2009 Pearl Meister Greengard Prize goes to pioneering geneticist http://www.medworm.com/index.php?rid=2919499&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D989 The 2009 Pearl Meister Greengard Prize recognizes Suzanne Cory, a world-renowned geneticist and pioneering scientific leader. The first woman to serve as director of Australia’s prestigious Walter and Eliza Hall Institute, she has been an influential force in shaping science policy in her nation. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2919499 Thu, 22 Oct 2009 22:00:00 +0100 2919499 Checkered history of mother and daughter cells explains cell cycle differences http://www.medworm.com/index.php?rid=2908040&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D986 In preparing to divide, mother and daughter cells use different gears and levers to regulate their genes. A collaboration between two geneticists and their labs now reveals that this difference in gene expression ultimately affects the protein CLN3, the levels of which certify whether a cell is ready to commit to another grueling round of cell division. The work sets a new compass point for studying how cell division may go awry in different types of cancer. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2908040 Tue, 20 Oct 2009 01:00:00 +0100 2908040 Rockefeller postdoc named finalist for Eppendorf & Science Prize for Neurobiology http://www.medworm.com/index.php?rid=2908041&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D987 A panel of distinguished scientists and editors have named postdoc Max Heiman a finalist for the Eppendorf & Science Prize for Neurobiology. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2908041 Mon, 19 Oct 2009 19:15:00 +0100 2908041 Elaine Fuchs to receive 2010 L'Oréal-UNESCO prize for women scientists http://www.medworm.com/index.php?rid=2893802&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D984 Elaine Fuchs — one of five women scientists around the world selected by the L’Oréal-UNESCO For Women in Science partnership to receive the 2010 L’Oréal-UNESCO Awards in the Life Sciences — is honored for her contributions to our knowledge of skin biology and skin stem cells. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2893802 Wed, 14 Oct 2009 21:15:00 +0100 2893802 Immunologist Michel Nussenzweig elected to Institute of Medicine http://www.medworm.com/index.php?rid=2882465&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D983 The head of Rockefeller University’s Laboratory of Molecular Immunology, Nussenzweig’s considerable contributions to the field of immunology include insights into how autoimmune diseases progress and the development of methods that may lead to dendritic-cell vaccines. Nussenzweig is one of 14 current Rockefeller researchers who are members of the Institute of Medicine. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2882465 Mon, 12 Oct 2009 14:46:29 +0100 2882465 Transgenic songbirds provide new tool to understand the brain http://www.medworm.com/index.php?rid=2861866&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D978 Over the decades, scientists have learned a lot about the basic life processes shared by many animals — including people — by manipulating the DNA of the “lower” species, such as mice and worms. But to date, they have been unable to readily probe the genetic contribution to one higher cognitive capacity of particular interest — the ability to learn language from one another. Now scientists have worked out a method for altering the genes of the zebra finch, one of the handful of social animals that learn to “speak” in a way that is analogous to humans. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2861866 Mon, 05 Oct 2009 16:30:00 +0100 2861866 Clinical study to probe genetic link to Salmonella diseases http://www.medworm.com/index.php?rid=2850792&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D977 Unusual symptoms of Salmonella infection in certain children may be caused a genetic mutation, according to researchers at The Rockefeller University Hospital, where a new clinical study is examining the immune profiles of affected children. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2850792 Mon, 28 Sep 2009 21:15:00 +0100 2850792 “Promiscuous” protein interactions found in the nuclear pore complex http://www.medworm.com/index.php?rid=2841953&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D976 The NPC is the only way in or out of a cell’s nucleus. It plays a key role in cellular metabolism and signaling, and any malfunction in these pores can have lethal consequences. Now new research reveals further insights into the design of this evolutionarily ancient and little-understood transport machinery. The findings suggest that the nuclear pore complex takes on different formations to carry out its function. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2841953 Mon, 28 Sep 2009 20:00:00 +0100 2841953 Obesity researcher wins Keio Medical Science Prize http://www.medworm.com/index.php?rid=2838587&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D975 Jeffery Friedman shares the 14th Keio Medical Science Prize, awarded annually to researchers for outstanding achievements in the fields of life sciences and medicine, for the "discovery of leptin and the study of its physiological functions.” (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2838587 Mon, 28 Sep 2009 09:00:00 +0100 2838587 New model suggests how the brain might stay in balance http://www.medworm.com/index.php?rid=2831484&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D974 Physicists have theorized for decades about how neural networks might be able to accomplish the incredibly complex calculations the human brain performs all the time. But simply stabilizing such a powerful organic computer made up of 100 billion neurons and trillions of interconnections is no small matter. A new model proposes that the brain could use about half of its connections just to maintain a delicate balance of excitation and inhibition. And keep from going haywire. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2831484 Thu, 24 Sep 2009 16:30:00 +0100 2831484 Rockefeller virologists and MIT tissue engineers receive $5.8 million NIH grant to study hepatitis http://www.medworm.com/index.php?rid=2827540&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D972 Provided through the National Institutes of Health’s inaugural Transformative R01 grant program — a groundbreaking initiative designed to encourage high-risk research — the grant will run for five years and will fund efforts to elucidate the notoriously complex mechanisms underlying hepatitis B and C virus infection. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2827540 Thu, 24 Sep 2009 05:00:00 +0100 2827540 New Innovator Award goes to cancer researcher Sohail Tavazoie http://www.medworm.com/index.php?rid=2827539&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D971 One of Rockefeller’s newest faculty recruits, Tavazoie aims to identify small pieces of RNA, known as microRNAs, that may signal a high potential for metastasis or that can effectively distinguish between cancers that will be responsive to chemotherapy and those that would be better candidates for alternative and experimental therapies. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2827539 Thu, 24 Sep 2009 05:00:00 +0100 2827539 Elaine Fuchs receives National Medal of Science http://www.medworm.com/index.php?rid=2807065&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D969 Elaine Fuchs, Rebecca C. Lancefield Professor, is being honored “for her pioneering use of cell biology and molecular genetics in mice to understand the basis of inherited diseases in humans and her outstanding contributions to our understanding of the biology of skin and its disorders, including her notable investigations of adult skin stem cells, cancers and genetic syndromes.” (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2807065 Thu, 17 Sep 2009 21:30:00 +0100 2807065 Two Rockefeller scientists named finalists for Blavatnik Awards for Young Scientists http://www.medworm.com/index.php?rid=2799873&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D967 Associate Professor and head of laboratory Shai Shaham and Postdoctoral Fellow Sreekanth H. Chalasani are finalists in the third annual competition administered by the New York Academy of Sciences. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2799873 Mon, 14 Sep 2009 22:45:00 +0100 2799873 To better control Chagas disease, focus funds more efficiently, scientists say http://www.medworm.com/index.php?rid=2781403&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D964 Controlling the bug that causes Chagas disease, a chronic infection of 10 million people worldwide with no available cures or vaccines, is the primary goal of public health officials in the developing world. New research suggests that insecticide spraying should be concentrated during the seasons when bugs disperse over long distances to make the best use of limited resources. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2781403 Wed, 09 Sep 2009 21:15:00 +0100 2781403 Two proteins enable skin cells to regenerate http://www.medworm.com/index.php?rid=2765368&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D961 Skin cells that have lost their luster flake off and are replaced by new ones that push their way up to the surface. In new research that further dissects how stem cells specialize into tissue cells, scientists now show how these new skin cells arise — work that may one day hold promise for burn victims. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2765368 Thu, 03 Sep 2009 21:00:00 +0100 2765368 New technique allows scientists to penetrate yeast cells’ hard exterior http://www.medworm.com/index.php?rid=2765369&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D963 Injections are a useful tool for cell biologists. They allow researchers to administer proteins and chemicals directly to the inside of a single cell. A new technique, developed at Rockefeller University, makes this possible for the first time in cells that were previously considered too hard to be penetrated by traditional methods. By using a micropipette like a saw and combining it with a small electric motor, scientists have now successfully administered fluorescent proteins to yeast cells. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2765369 Thu, 03 Sep 2009 19:00:00 +0100 2765369 New research supports model for nuclear pore complex http://www.medworm.com/index.php?rid=2711604&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D958 The pores that control what passes in and out of the cell nucleus play a crucial role in the cell’s metabolism and signaling. Defects in structure and function of these gatekeepers, known as nuclear pore complexes, can have lethal consequences. New research reveals secrets about what may be a key design feature of these structures, a flexibility enabling the import and export of large molecules. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2711604 Tue, 18 Aug 2009 16:00:00 +0100 2711604 Scientists identify stomach’s timekeepers of hunger http://www.medworm.com/index.php?rid=2698942&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D956 The problem with dieting is that it leaves you hungry. But scientists have now identified specific cells in the stomach that are behind the body’s craving for food. In new research that has implications for the treatment of obesity, scientists have shown that these cells release the hormone ghrelin, which in animals causes foraging behavior even when they’re not hungry. The findings could help researchers develop drugs that would curb dieters’ appetites before that first bite. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2698942 Thu, 13 Aug 2009 16:45:00 +0100 2698942 Anthrax bacteria conspire with viruses to stay alive http://www.medworm.com/index.php?rid=2694605&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D955 New research suggests that anthrax-causing bacteria work synergistically with viruses to extend each other’s life spans. The work puts scientists on a new playing field in the fight against biological warfare and antibiotic-resistance, and also calls into question the degree to which our genomes are the sole masters of our fates. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2694605 Wed, 12 Aug 2009 16:15:00 +0100 2694605 Model suggests how life’s code emerged from primordial soup http://www.medworm.com/index.php?rid=2681387&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D954 It would seem a stunning improbability for a whirlwind to spin through a junkyard and leave behind a fully assembled jumbo jet. This colorful metaphor by astronomer Fred Hoyle points out the difficulties encountered by scientists when they try to understand how Life could have emerged billions of years ago. Researchers at Rockefeller University now show how crude pieces of a genetic system could self-assemble and generate the rules of Life’s most fundamental code. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2681387 Fri, 07 Aug 2009 17:45:00 +0100 2681387 Acute stress improves working memory, research suggests http://www.medworm.com/index.php?rid=2648525&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D952 Stress is no fun. Chronic stress can ruin your health. But the body’s response to troubling situations is not without benefit. New research shows that after a brief encounter with a stressful scenario, the resulting acute stress actually makes you smarter. Or at least it improves the working memory of rats by ramping up production of neurotransmitters in the prefrontal cortex, a key region of the brain controlling emotion and cognition. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2648525 Mon, 27 Jul 2009 22:00:00 +0100 2648525 Tenure awarded to RNA researcher Thomas Tuschl http://www.medworm.com/index.php?rid=2637450&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D951 The university promotes a biochemist who researches RNA interference (RNAi), the process by which small RNA molecules interfere with gene expression. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2637450 Fri, 24 Jul 2009 22:00:00 +0100 2637450 Songbirds’ elaborate cries for food show first signs of vocal learning http://www.medworm.com/index.php?rid=2633720&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D950 How a handful of social animals ever learned to actively style their vocal communication is a question that has dogged biologists for generations. New research in chipping sparrows suggests that the talent originally appeared in these songbirds as a competition for food among siblings and later evolved into vocal imitation used in territorial defense and courtship. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2633720 Thu, 23 Jul 2009 20:45:00 +0100 2633720 New imaging studies reveal mechanics of neuron migration http://www.medworm.com/index.php?rid=2629410&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D949 In the developing brain, generations of young neurons undergo a staged migration, with the earliest-born cells staying relatively close to their birthplace and subsequent generations traveling further, ultimately stratifying into six neuronal layers in the mature brain. For the first time, imaging studies have identified the “motors” that propel this unique form of cell migration, giving insight into the delicate layering of the brain that underlies the formation of synaptic circuitry. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2629410 Wed, 22 Jul 2009 18:00:00 +0100 2629410 Head of Rockefeller University Press named 2009 SPARC Innovator http://www.medworm.com/index.php?rid=2601266&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D948 Mike Rossner, executive director of The Rockefeller University Press, has been named the newest SPARC Innovator by the Scholarly Publishing and Academic Resources Coalition. Announced last week, the award honors Rossner for his work as a proponent of data integrity in and wider public access to scientific publishing. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2601266 Tue, 14 Jul 2009 15:15:00 +0100 2601266 By manipulating oxygen, scientists coax bacteria into a wave http://www.medworm.com/index.php?rid=2597608&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D947 Bacteria know that they are too small to make an impact individually. So they wait; they multiply, and then they engage in behaviors that are only successful when all cells participate in unison. There are hundreds of behaviors that bacteria carry out in such communities. Now researchers have discovered that bacteria form an unusual solitary wave - a behavior that has never been observed or described before in a living system. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2597608 Mon, 13 Jul 2009 21:15:00 +0100 2597608 Research suggests core nuclear pore elements shared by all eukaryotes http://www.medworm.com/index.php?rid=2590904&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D946 About 1.7 billion years ago, the cell nucleus burst onto the scene, sequestering the cell’s genetic material inside a protective inner membrane and setting the stage for the evolution of increasingly sophisticated creatures from yeast, say, to plants and human beings. Now research shows that one of the most basic design principles of this new eukaryotic life-form — the gatekeeper to the cell nucleus known as the nuclear pore complex — is largely shared across even the most distantly related eukaryotes. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2590904 Thu, 09 Jul 2009 21:45:00 +0100 2590904 Handle with care: Telomeres resemble DNA fragile sites http://www.medworm.com/index.php?rid=2587673&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D945 Although telomeres are fragile, they don’t have to be handled with care. Researchers at Rockefeller University now show that what keeps our fragile telomeres from falling apart is a protein known as TRF1 that ensures the smooth progression of DNA replication to the end of a chromosome. The work not only shows how telomeres help chromosomes protect their vulnerable ends but also reveals how the genome is made more stable by them. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2587673 Thu, 09 Jul 2009 18:30:00 +0100 2587673 Cells use import machinery to export their goods as well http://www.medworm.com/index.php?rid=2569218&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D942 Cells use bubbles called vesicles to ferry cargo to and from the membrane. Scientists long believed that this importing and exporting were independent processes. But by imaging individual vesicles as they are fusing with the cell membrane, researchers reveal that these processes have a lot in common: Certain molecules handle cargo moving in both directions. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2569218 Thu, 02 Jul 2009 19:15:00 +0100 2569218 Michael Young receives Gruber Foundation’s 2009 Neuroscience Prize http://www.medworm.com/index.php?rid=2569219&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D944 Michael W. Young, Richard and Jeanne Fisher Professor and head of the Laboratory of Genetics at Rockefeller University, has received the 2009 Neuroscience Prize of the Peter and Patricia Gruber Foundation for groundbreaking discoveries of the molecular mechanisms that control circadian rhythms in the nervous system. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2569219 Wed, 01 Jul 2009 21:15:00 +0100 2569219 Genome-wide map shows precisely where microRNAs do their work http://www.medworm.com/index.php?rid=2503706&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D939 MicroRNAs are the newest kid on the genetic block. By regulating the unzipping of genetic information, these tiny molecules have set the scientific world alight with their therapeutic potential and wide-ranging applications. But the question remains: How do they work? By using a technique that molecularly cements proteins to RNAs, Rockefeller scientists have decoded a map of microRNA-messenger RNA interactions in the mouse brain, an advance that holds promise for biology and human disease. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2503706 Wed, 17 Jun 2009 18:00:00 +0100 2503706 Jeffrey Friedman receives Shaw Prize for discovery of leptin http://www.medworm.com/index.php?rid=2503707&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D940 Jeffrey Friedman, Marilyn M. Simpson Professor and head of the Laboratory of Molecular Genetics at Rockefeller, received the 2009 Shaw Prize in Life Science and Medicine. He shares the $1 million award, known as the Nobel Prize of the East, with the Jackson Laboratory's Douglas L. Coleman for their work leading to the discovery of leptin, a hormone that regulates food intake and body weight. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2503707 Tue, 16 Jun 2009 17:00:00 +0100 2503707 Research identifies 3D structure of key nuclear pore building block http://www.medworm.com/index.php?rid=2462725&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D937 New research into the molecular machine that filters all information traveling in or out of the cell nucleus contributes to an unfolding picture of cellular evolution that shows a common architecture for the nuclear pore complex (NPC) and the vehicles that transport material between different parts of the cell. Scientists have for the first time glimpsed in three dimensions the subcomplex of the NPC that is its key building block. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2462725 Sun, 07 Jun 2009 18:00:00 +0100 2462725 Report identifies early childhood conditions that lead to adult health disparities http://www.medworm.com/index.php?rid=2455916&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D938 The origins of many adult diseases can be traced to early negative experiences associated with social class and other markers of disadvantage. Confronting the causes of adversity before and shortly after birth may be a promising way to improve adult health and reduce premature deaths, researchers argue in a paper published today in JAMA: The Journal of the American Medical Association. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2455916 Tue, 02 Jun 2009 19:45:00 +0100 2455916 Misreading of histone code linked to human cancer http://www.medworm.com/index.php?rid=2503708&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D936 The development of blood from stem cell to fully formed blood cell follows a genetically determined program. When it doesn’t work properly, genetic mutations can cause the developing cells to turn cancerous. In research published in the journal Nature, Rockefeller University scientists show for the first time that a misreading of blood cells’ histone code is responsible for acute myeloid leukemia, a rare form of the deadly blood cancer. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2503708 Mon, 01 Jun 2009 15:00:00 +0100 2503708 Genetic profiling reveals genes active in the earliest brain circuit construction http://www.medworm.com/index.php?rid=2446216&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D935 Screening for genes that guide the earliest formation of the embryonic brain, researchers identified 229 specifically responsible for subplate neurons, which form the initial scaffolding for assembling cortical circuits. The work indicates the breadth of factors involved in initial neurogenesis and provides investigators with a biochemical handle to start investigating the various contributions. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2446216 Fri, 29 May 2009 20:15:00 +0100 2446216 New Rockefeller faculty member studies mechanisms of DNA repair http://www.medworm.com/index.php?rid=2439803&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D934 Agata Smogorzewska, a physician-scientist whose research focuses on DNA repair and on the molecular basis of Fanconi anemia, a genomic instability syndrome that leads to leukemia and other forms of cancer, will join The Rockefeller University as head of the Laboratory of Genome Maintenance. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2439803 Wed, 27 May 2009 17:15:00 +0100 2439803 To spread, skin cancer attacks immune dendritic cells http://www.medworm.com/index.php?rid=2439804&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D933 By knocking out or beguiling dendritic cells, some cancer cells can slip the defenses of the immune system and sack the unsuspecting body. Dendritic cells taken from one of the most common types of skin cancer have most of the known genetic and physiologic hallmarks of their able-bodied fellows in healthy skin tissue. But they fail to stimulate an effective immune response. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2439804 Tue, 26 May 2009 18:00:00 +0100 2439804 Rockefeller University names Robert Sapolsky 2008 Lewis Thomas Prize winner http://www.medworm.com/index.php?rid=2503709&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D932 Primatologist and Stanford University neuroscientist Robert M. Sapolsky has been named the recipient of Rockefeller University’s Lewis Thomas Prize for Writing about Science for 2008. The award recognizes Sapolsky’s 2001 publication A Primate’s Memoir: A Neuroscientist’s Unconventional Life Among the Baboons and will be presented to him at a ceremony at the university’s Caspary Auditorium on June 2. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2503709 Mon, 18 May 2009 15:15:00 +0100 2503709 For different species, different functions for embryonic microRNAs http://www.medworm.com/index.php?rid=2413116&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D930 Researchers at The Rockefeller University have discovered that a family of microRNAs that regulates early embryonic development is evolutionarily conserved from fish to amphibians and humans, but its function is not. The findings are a warning: Scientists should not assume that what they learn about microRNAs in animal studies will hold true for people. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2413116 Thu, 14 May 2009 14:00:00 +0100 2413116 Scientists develop tool to study a deadly parasite’s histone code http://www.medworm.com/index.php?rid=2503710&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D931 In a genome-wide study, scientists are the first to map the epigenetic changes that are likely to play a role in the molecular origami of transcription initiation in Trypanosoma brucei, the deadly single-celled parasite responsible for African sleeping sickness. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2503710 Wed, 13 May 2009 21:00:00 +0100 2503710 New tag could enable more detailed structural studies of mammalian proteins http://www.medworm.com/index.php?rid=2396729&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D929 By effectively expanding the genetic code, new research reveals a method that could theoretically be adapted to place a fluorescent probe at any position in any protein in a mammalian cell. The new technology could enable single-molecule fluorescent studies in live cells. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2396729 Wed, 06 May 2009 20:15:00 +0100 2396729 Eric Siggia joins National Academy of Sciences http://www.medworm.com/index.php?rid=2396730&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D928 Eric D. Siggia, whose laboratory is interested in applying informatics approaches to study gene expression and other biological problems, has been elected to the National Academy of Sciences, one of the highest honors given to a scientist or engineer in the United States. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2396730 Tue, 05 May 2009 21:30:00 +0100 2396730 New sequencing technique to prod medical benefits from killer venom http://www.medworm.com/index.php?rid=2380030&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D925 Any given venom can contain hundreds of toxins with different functions, but teasing them out of a venom sample is no mean feat. Researchers at Rockefeller University have developed a method of protein sequencing that can speed up the decoding of these toxins by orders of magnitude, raising the prospect that they will be able to test a great many of these molecules for their medical potential. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2380030 Wed, 29 Apr 2009 17:45:00 +0100 2380030 New clinical study probes how light fights psoriasis http://www.medworm.com/index.php?rid=2374187&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D926 A new clinical trial under way at The Rockefeller University Hospital will literally shine light on psoriasis in hopes of finding out exactly how phototherapy works. Narrowband ultraviolet light B (UVB) therapy is known to kill off T cells, which are partly to blame for the inflammation caused by the disease. Exactly how it does that remains a mystery. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2374187 Tue, 28 Apr 2009 18:00:00 +0100 2374187 Level of cellular stress determines longevity of retinal cells http://www.medworm.com/index.php?rid=2503711&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D924 Scientists expose neurons in the fruit fly retina — and other cells — to moderate cellular stress and find a protective effect, shedding light on potential therapeutic targets that can protect against or delay the onset of neurodegeneration. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2503711 Mon, 27 Apr 2009 17:00:00 +0100 2503711 Ralph Steinman awarded 2009 Albany Medical Center Prize http://www.medworm.com/index.php?rid=2503712&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D923 Head of Rockefeller University’s Laboratory of Cellular Physiology and Immunology and the discoverer of dendritic cells, Ralph M. Steinman is one of three recipients of this year’s Albany Medical Center Prize, at $500,000 the largest scientific prize in the country. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2503712 Fri, 24 Apr 2009 15:30:00 +0100 2503712 $10 million gift from the Simons Foundation to support new initiative with Institute for Advanced Study http://www.medworm.com/index.php?rid=2503713&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D920 A new joint initiative, which builds on the complementary strengths of the institute and the university, will involve biologists, mathematicians, physicists and computer scientists exploring quantitative and theoretical approaches to biological problems. Rockefeller’s Stanislas Leibler will be the initiative’s first joint professor. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2503713 Wed, 22 Apr 2009 16:45:00 +0100 2503713 Rockefeller University Hospital opens new Sleep Research Center http://www.medworm.com/index.php?rid=2503714&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D919 A good night’s sleep is good for your health, but the details have long been sketchy. Now, after decades of study into the relationship between sleep patterns and health in general, science is pointing to the often overlooked role of sleep in particular diseases — from cancer to diabetes to Parkinson’s — and The Rockefeller University Hospital is adding sleep studies to its roster of clinical initiatives, with the opening of a new Sleep Research Center. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2503714 Fri, 17 Apr 2009 15:00:00 +0100 2503714 New nucleotide could revolutionize epigenetics http://www.medworm.com/index.php?rid=2503715&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D918 Genes alone cannot explain the vast differences in the complexity of life. Scientists have found that what makes a worm and a human so much different isn’t the amount of DNA they carry, which is about the same, but rather the dynamic regulation of those genes by nongenetic factors: epigenetics. New research at The Rockefeller University has now uncovered a novel system of epigenetic regulation, one that adds a new nucleotide to the mammalian DNA code. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2503715 Thu, 16 Apr 2009 19:15:00 +0100 2503715 Research defines dendritic cell lineage http://www.medworm.com/index.php?rid=2283021&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D908 For more than 30 years, controversy has reigned over the question of how exactly to differentiate dendritic cells from their immune cell cousins, the monocytes. Now, research published in Science identifies a precursor to classical spleen dendritic cells that defines where such cells diverge from monocytes. The findings could have important implications for research on dendritic cell-based vaccines all over the world. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2283021 Thu, 19 Mar 2009 21:45:00 +0100 2283021 Epigenetic mark guides stem cells toward their destiny http://www.medworm.com/index.php?rid=2283022&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D909 Not all stem cells are completely blank slates. Some, known as adult stem cells, have already partially embraced their fates. Researchers now highlight the interactions between genetic and epigenetic regulators in skin stem cells and how these interactions change as stem cells begin the process of specialization. The findings may also lead to new therapies for prematurely born infants who have not yet fully formed the skin. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2283022 Thu, 19 Mar 2009 20:00:00 +0100 2283022 Rockefeller receives new $4.8 million state grant to fund stem cell research http://www.medworm.com/index.php?rid=2283023&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D907 The grant from New York will establish new facilities for studying the molecular basis of how stem cells are maintained and how they differentiate. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2283023 Wed, 18 Mar 2009 16:15:00 +0100 2283023 Scientists discover master regulator of motor neuron firing http://www.medworm.com/index.php?rid=2267272&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D904 When the Human Genome Project was complete, DNA bowed out of the limelight and gave way to RNA as a major player in genetic regulation. New findings that reveal the master architect behind a functioning motor neuron not only mirror this ideological shift but further point to the increasingly indisputable role of RNA as the molecule behind biological complexity. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2267272 Fri, 13 Mar 2009 21:00:00 +0100 2267272 2008 Pearl Meister Greengard Prize awarded to three leading biologists http://www.medworm.com/index.php?rid=2257757&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D903 The Rockefeller University has announced the winners of the fifth annual Pearl Meister Greengard Prize: Elizabeth H. Blackburn of the University of California, San Francisco; Carol W. Greider of The Johns Hopkins University School of Medicine; and Vicki Lundblad of the Salk Institute for Biological Studies. The three women are pioneers in the study of the enzyme telomerase, which plays a central role in the repair of telomeres. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2257757 Thu, 12 Mar 2009 16:15:00 +0100 2257757 Researchers unveil new monkey model for HIV http://www.medworm.com/index.php?rid=2228415&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D895 For the first time, scientists have succeeded in engineering a strain of HIV-1 that they can study in monkeys. Just one gene different from the deadly retrovirus that works all too well in humans, the new strain spreads in pig-tailed macaques almost as ferociously as it does in humans. Researchers at The Rockefeller University have already used it to demonstrate one method for preventing HIV-1 infection. With some minor changes, it could become a valuable model for vetting vaccine candidates. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2228415 Mon, 02 Mar 2009 21:45:00 +0100 2228415 Brain protein may be a target for fast-acting antidepressants http://www.medworm.com/index.php?rid=2212726&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D891 It takes weeks or months for the effect of most antidepressants to kick in, time that can feel like an eternity to those who need the drugs the most. But new research suggests that a protein called p11 may be the key to developing drugs that begin to work in as little as two days. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2212726 Tue, 24 Feb 2009 17:30:00 +0100 2212726 Gene linked to anxious behavior in mice http://www.medworm.com/index.php?rid=2202719&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D886 Mice and men are different in many ways, of course, especially when it comes to the psychological. But new research linking a gene in mice to anxious behavior raises the prospect that we get some anxiety disorders from a piece of DNA we share with the little mammals. The gene, Lynx2, alters neurotransmission in parts of the mouse brain associated with anxiety. The same parts are associated with anxiety in humans. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2202719 Thu, 19 Feb 2009 14:30:00 +0100 2202719 Dendritic cells as a new player in arteries and heart valves http://www.medworm.com/index.php?rid=2192532&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D885 Discovered by Ralph M. Steinman in 1973, dendritic cells have been implicated in early immune responses such as graft rejection, resistance to tumors and autoimmune diseases. New research shows that these relatively rare immune cells may play a role in heart disease as well. Experiments show that dendritic cells project their dendrites into the bloodstream, where they can capture foreign invaders and turn them over to T cells for destruction. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2192532 Mon, 16 Feb 2009 20:00:00 +0100 2192532 Stress disrupts human thinking, but the brain can bounce back http://www.medworm.com/index.php?rid=2138996&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D873 Med school students prepping for their boards and rodents digging for food have a bit of psychology in common: Stress hampers their nimbler thinking abilities. A new neuroimaging study, building on earlier rodent research, shows that stressed-out men, like rats, have a hard time shifting their attention from one task to another. But the work holds good news too, for both rats and humans: Their brains are resilient. Less than one month after the stress disappears, the quick thinking returns. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2138996 Tue, 27 Jan 2009 16:00:00 +0100 2138996 Scientists discover an ancient odor-detecting mechanism in insects http://www.medworm.com/index.php?rid=2090902&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D867 A newly discovered family of receptors in the fly nose fills in a missing piece of the insect olfactory system, and also suggests a new role for a class of receptors long believed to be confined to the depths of the brain. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2090902 Thu, 08 Jan 2009 18:30:00 +0100 2090902 Rockefeller microbiologist tests safety of spiked eggnog http://www.medworm.com/index.php?rid=2054891&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D866 An experiment designed to test the safety of consuming eggnog made from raw eggs suggests that, in general, few bacteria survive in a mixture containing 20 percent rum and bourbon. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2054891 Fri, 19 Dec 2008 18:45:00 +0100 2054891 Single letter in the human genome points to risk for high cholesterol http://www.medworm.com/index.php?rid=2043386&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D865 In the search for genes that affect how humans synthesize, process and break down cholesterol, a consortium of researchers led by Rockefeller University scientists has found a single letter in the genome that is associated with elevated LDL cholesterol levels, one of the leading health concerns that has come to dominate the 21st century. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2043386 Tue, 16 Dec 2008 18:30:00 +0100 2043386 An enzyme that mutates antibodies also targets a cancer-causing oncogene http://www.medworm.com/index.php?rid=2029629&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D862 The human immune system runs a risky business. It mutates its own DNA to diversify defenses against foreign invaders it has never before encountered. Unfortunately, these mutations sometimes miss the mark, and the result can be lethal cancer. Now Rockefeller University scientists have found that the same enzyme that enables an effective immune response is also responsible for the DNA breaks that cause lymphomas. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=2029629 Thu, 11 Dec 2008 16:30:00 +0100 2029629 Tom Muir, Paul Nurse honored at Science and the City Gala http://www.medworm.com/index.php?rid=1970957&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D854 The New York Academy of Sciences has honored Rockefeller University professor Tom W. Muir with a Blavatnik Award for Young Scientists, and also presented Rockefeller president Paul Nurse with a Science and the City Award for Outstanding Accomplishments in New York City. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=1970957 Tue, 18 Nov 2008 22:30:00 +0100 1970957 New clinical study will help doctors assess abnormal bleeding http://www.medworm.com/index.php?rid=1931513&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D844 A new assessment tool being tested at The Rockefeller University Hospital may help physicians and researchers more accurately determine what is inside and outside the normal range of bleeding symptoms. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=1931513 Mon, 03 Nov 2008 22:00:00 +0100 1931513 By imaging live cells, researchers show how hepatitis C replicates http://www.medworm.com/index.php?rid=1922240&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D839 The hepatitis C virus is a prolific replicator, able to produce up to a trillion particles per day in an infected person. By using live imaging, researchers now know how. Their research shows that within an infected cell, the virus uses a combination of big viral factories and tiny, mobile replication complexes to efficiently churn out copies. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=1922240 Thu, 30 Oct 2008 19:00:00 +0100 1922240 Plant virus spreads by making life easy for crop pests http://www.medworm.com/index.php?rid=1918767&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D841 An ancient virus uses subterfuge to trick its host plant into lowering its defenses against pests, according to new research from The Rockefeller University. The result is that the pests that carry the virus flourish, spreading the virus ever faster. Researchers show how one molecule is behind all the mischief. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=1918767 Wed, 29 Oct 2008 22:00:00 +0100 1918767 In mice, anxiety is linked to immune system http://www.medworm.com/index.php?rid=1912616&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D838 In groundbreaking research that pushes the knowledge of how the two most complicated systems in the body are linked, researchers reveal that immune cells in the brain directly influence how mice normally behave in stressful situations. The work is the first ever to genetically link mast cells to anxiety, and opens new doors for drugs that target immune cells in the brain to regulate emotions. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=1912616 Mon, 27 Oct 2008 21:45:00 +0100 1912616 A new role for a critical DNA repair molecule in the immune system http://www.medworm.com/index.php?rid=1907033&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D835 Researchers find that a molecule that helps repair broken DNA is required for the genetic reshuffling that enables the immune system to adapt to new threats. The finding furthers our understanding of a process that is fundamental to our immune response but can also lead to cancers and other diseases when it falters. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=1907033 Fri, 24 Oct 2008 19:45:00 +0100 1907033 Molecule stops DNA replication in its tracks http://www.medworm.com/index.php?rid=1889433&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D832 When a dividing cell duplicates its genetic material, a molecular machine called a sliding clamp travels along the DNA double helix, tethering the proteins that perform the replication. Rockefeller University scientists have discovered a small molecule that stops the sliding clamp in its tracks, a finding that will enable researchers to better study the proteins that duplicate DNA, and may ultimately provide a platform for developing improved antibiotics. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=1889433 Fri, 17 Oct 2008 15:15:00 +0100 1889433 Study specifies chemical pathway for ions through the cell membrane http://www.medworm.com/index.php?rid=1889434&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D831 A new discovery reveals the details of a process that is an elemental part of life itself. By painstakingly replacing each amino acid throughout the interior of a protein pump that moves charged particles in and out of every animal cell, Rockefeller University scientists have uncovered the road map that those ions follow across the cell membrane. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=1889434 Mon, 13 Oct 2008 19:45:00 +0100 1889434 Four Rockefeller researchers named finalists in Blavatnik Awards for Young Scientists http://www.medworm.com/index.php?rid=1889435&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D830 Head of laboratory Tom W. Muir, postdocs Valerie Horsley and Andreas Keller and former postdoc Matthew Evans have been named finalists for the second annual Blavatnik Awards for Young Scientists. Established by the New York Academy of Sciences and the Blavatnik Charitable Foundation, the awards recognize the contributions of young scientists and engineers in New York, New Jersey and Connecticut. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=1889435 Fri, 10 Oct 2008 13:00:00 +0100 1889435 Newly identified cells make fat http://www.medworm.com/index.php?rid=1889436&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D826 By using a mouse that lacks fat cells and observing the growth of fat after injections of different kinds of immature cells, Rockefeller University scientists have discovered an important fat precursor cell that may in time explain how changes in the numbers of fat cells might increase and lead to obesity. The finding could also have implications for understanding how fat cells affect conditions such as diabetes and cardiovascular disease. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=1889436 Fri, 03 Oct 2008 20:30:00 +0100 1889436 Scientists identify a molecule that coordinates the movement of cells http://www.medworm.com/index.php?rid=1889437&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D825 An elaborate track of exceptionally strong proteins known as the extracellular matrix allows cells to migrate toward wounds and heal them. It also gives cancer cells a way to spread. Now, new research from Rockefeller University shows that a recently discovered molecule called ACF7 orchestrates and powers this directed movement. The finding offers a new potential target for setting up a roadblock for the spread of cancer. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=1889437 Thu, 02 Oct 2008 20:15:00 +0100 1889437 A DNA-based vaccine shows promise against avian flu http://www.medworm.com/index.php?rid=1889438&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D824 By combining a newly discovered application technique with a broad genetic target, researchers may have created a potent vaccine against the virus. If successful, the new vaccine could be rapidly produced and effective against a broad spectrum of viral strains. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=1889438 Tue, 30 Sep 2008 19:00:00 +0100 1889438 New formula predicts how people will migrate in coming decades http://www.medworm.com/index.php?rid=1889439&cid=s_38118_61_f&fid=38118&url=http%3A%2F%2Fnewswire.rockefeller.edu%2F%3Fpage%3Dengine%26id%3D821 Countries use population projections to estimate local needs for things like jobs, schools, housing and health care, but coming up with those projections has been an inexact science. A newly developed, more precise formula to describe how people move between countries could lead to better use of resources and improved economic conditions. (Source: The Rockefeller University Newswire) The Rockefeller University Newswire organizations http://www.medworm.com/rss/comments.php?id=1889439 Mon, 29 Sep 2008 17:45:00 +0100 1889439