MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'The Turkish Journal of Pediatrics' source. Sat, 10 Oct 2009 19:38:21 +0100 http://www.medworm.com/index.php?rid=2538216&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19480318%26dopt%3DAbstract Authors: Gorzelany K, Dursun A, Coşkun T, Kalkanoğlu-Sivri SH, Gökçay GF, Demirkol M, Feyen O, Wendel U In maple syrup urine disease (MSUD), disease-causing mutations can affect the BCKDHA, BCKDHB or DBT genes encoding for the E1alpha, E1beta and E2 subunits of the multienzyme branched-chain alpha-keto acid dehydrogenase (BCKDH) complex. Here we summarize the MSUD genotypes of a cohort of 32 unrelated Turkish patients in whom both alleles at a single gene locus harbored presumable disease-causing nucleotide changes. The patients had different forms of MSUD, ranging from the severe classical form (26 patients) to severe and mild variants (6 patients). In all except two patients (92%), the mutations occurred homozygously. The mutational spectrum included 27 differen... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538216 Sun, 01 Mar 2009 00:00:00 +0100 2538216 http://www.medworm.com/index.php?rid=2538215&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19480319%26dopt%3DAbstract This study was performed to document the factors determining allergic signs and symptoms in early childhood in a group of Turkish children. Children followed at the Well-Baby Clinic who were 2 to 4 years were invited and re-evaluated. In addition to face-to-face questionnaire for allergic signs and symptoms and review of files, skin prick test was performed. The associations between risk factors and different aspects of atopy were analyzed. One hundred and nine patients (mean age: 31.6 +/- 3.5 months) were included in the study. All had been breast-fed with mean exclusive and total breastfeeding durations of 3.3 +/- 2.7 and 13.3 +/- 7.2 months, respectively. Eight children had physician-diagnosed allergic diseases (4 atopic eczema, 3 bronchial asthma and 1 food allergy) and the overall pre... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538215 Sun, 01 Mar 2009 00:00:00 +0100 2538215 http://www.medworm.com/index.php?rid=2538214&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19480320%26dopt%3DAbstract Authors: Tezer H, Siklar Z, Dallar Y, Doğankoç S Nutritional rickets is re-emerging as a significant health problem among children. We determined the frequency of nutritional rickets and vitamin D deficiency among hospitalized children and the effective factors. During a one-year period, 305 hospitalized children (ages between 0 to 3 years) were evaluated for clinical and biochemical markers of vitamin D deficient rickets and related factors. Twenty-one of them (6.8%) were diagnosed as nutritional vitamin D deficiency and rickets. Most of the children diagnosed were under one year old (16/21, 76.2%). Fourteen vitamin D deficient rachitic children were admitted to the hospital with infectious conditions, and most of them were respiratory tract infection. The rachitic group wa... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538214 Sun, 01 Mar 2009 00:00:00 +0100 2538214 http://www.medworm.com/index.php?rid=2538213&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19480321%26dopt%3DAbstract Authors: Baykan A, Karagöz T, Celiker A The aim of this study was to report the intermediate follow-up results of stent implantation for coarctation of the aorta in children from Turkey. Patients with native or postoperative coarctation, who had abnormal flow at the descending aorta exceeding diastolic phase on Doppler echocardiography or upper extremity hypertension, underwent endovascular stent implantation. Ten patients with a mean age of 12.4 +/- 5.5 years (6-23 years) underwent stent implantation between January 2001 and September 2006. Of these, three had previous surgical repair, and the remainder were native coarctation. Palmaz, Genesis and Numed CP stents were used. All the implantations were successful and there was no major complication during the procedure. The follow-... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538213 Sun, 01 Mar 2009 00:00:00 +0100 2538213 http://www.medworm.com/index.php?rid=2538212&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19480322%26dopt%3DAbstract This study was conducted to determine the seroprevalence of hepatitis B virus (HBV) infection in the Turkish population in Northern Cyprus. The secondary aim of this study was to assess the impact of the universal infant hepatitis B vaccination program, which started in 1998. A total of 600 persons 1- to 30-years-old were selected for the study with cluster sampling. The information on sociodemographic characteristics was gathered for each participant and in 585 of them, hepatitis B surface antigen (HBsAg), anti-hepatitis B surface antigen antibody (anti-HBs) and anticore antibody (anti-HBc) were tested. The overall prevalence of anti-HBc and HBsAg carriage was 13.2% and 0.85%, respectively. Old age and low parental educational level were the major independent risk factors for HBV transmis... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538212 Sun, 01 Mar 2009 00:00:00 +0100 2538212 http://www.medworm.com/index.php?rid=2538211&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19480323%26dopt%3DAbstract Authors: Aydoğdu S, Arikan C, Cakir M, Baran M, Yüksekkaya HA, Saz UE, Arslan MT Foreign body ingestion (FBI) is a common problem in the pediatric population. Even though morbidity and mortality due to foreign body ingestion are rare in childhood, they may cause serious anxiety in parents. We aimed to analyze the clinical presentation, etiology and management strategy of FBI in children in our country. Records of children admitting with a history of FBI over a three-year period were reviewed retrospectively. Data regarding gender, age, type of the ingested body, management strategy and outcome of the patients were recorded. Of 176 children, 98 (55.6%) were male. Mean age +/- SD of the patients was 3.75 +/- 4.25 years, and most of the patients were below four years of age (71... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538211 Sun, 01 Mar 2009 00:00:00 +0100 2538211 http://www.medworm.com/index.php?rid=2538210&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19480324%26dopt%3DAbstract Authors: Kuşkonmaz B, Yurdakök K, Yalçin SS, Ozmert E The clinical and laboratory findings of 290 cases of bloody diarrhea who presented to the department of Diarrhea Training and Treatment between June 1998 and May 2002 were investigated, and compared to those of two consecutive cases who had watery diarrhea. The bloody diarrhea group had higher mean age, higher frequencies of diarrhea, lower frequencies of vomiting, and shorter durations of diarrhea at the time of admission as compared to the watery diarrhea group. The number of cases using antibiotics before the onset of diarrheal attacks was higher in the bloody diarrhea group, and sulbactam-ampicillin had been used more frequently in this group. The presence of dehydration was similar in the two groups, but the occ... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538210 Sun, 01 Mar 2009 00:00:00 +0100 2538210 http://www.medworm.com/index.php?rid=2538209&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19480325%26dopt%3DAbstract Authors: Kul M, Demirkaya E, Ipçioğlu OM, Karadeniz RS, Tunç T, Vurucu S, Yeşil FG, Oztin H, Cakir E The aim of this study was to investigate the relationship between maternal risk factors, neonatal demographic features and asymmetric dimethylarginine (ADMA) levels in a randomly selected group of pregnancies during delivery. The subjects were categorized into five groups as having: no maternal risk factor, maternal hypertension, gestational diabetes, maternal smoking history, and meconium staining. Blood samples were taken from the mothers before delivery and from the umbilical vein after delivery. Mean ADMA levels were significantly lower in the cord blood when compared with maternal levels in all groups. Mean ADMA level of neonates in the meconium staining group... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538209 Sun, 01 Mar 2009 00:00:00 +0100 2538209 http://www.medworm.com/index.php?rid=2538208&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19480326%26dopt%3DAbstract Authors: Aydoğdu S, Cakir M, Yüksekkaya HA, Arikan C, Tümgör G, Baran M, Yağci RV We aimed to evaluate general features of children with chronic constipation and classified them according to the Iowa criteria and Rome II criteria in order to analyze applicability of these criteria in our population. The medical records of 485 children who were referred for chronic constipation over a six-year period were evaluated retrospectively. We found that 7.7% of the cases had an organic pathology, and short segment Hirschsprung disease was the leading cause. Other children (92.3%) were classified as functional constipation, with a mean age of 6.4 +/- 4 years and with slight male dominance. Encopresis was found in 117 children (51.7%) aged over four years, and was assoc... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538208 Sun, 01 Mar 2009 00:00:00 +0100 2538208 http://www.medworm.com/index.php?rid=2538207&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19480327%26dopt%3DAbstract Authors: Yüksel H, Yilmaz O, Kirmaz C, Eser E The aim of this study was to adapt the Pediatric Asthma Quality of Life Questionnaire (PAQLQ) into Turkish and to demonstrate its psychometric performance. After Turkish adaptation of the PAQLQ, this study was conducted on 122 children with asthma aged between 7 and 16 years. A sociodemographic form and PAQLQ and KINDL (a generic health-related quality of life instrument developed for children) questionnaires were applied. Reliability analysis consisted of internal consistency and item-total score correlations, while validity was tested by construct validity. Cronbach alpha scores for Activity (0.80), Symptoms (0.90), and Emotional (0.86) domains were satisfactory. Item versus subscale and total score correlations were significant. Cor... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538207 Sun, 01 Mar 2009 00:00:00 +0100 2538207 http://www.medworm.com/index.php?rid=2538206&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19480328%26dopt%3DAbstract Authors: Cangül H, Ozdemir O, Yakut T, Okan M, Morgan NV, Baytan B, Kurian MA, Spiegel R, Maher ER Here we report the clinical, neuroimaging, and molecular findings of a classic pantothenate kinase-associated neurodegeneration (PKAN) patient of Turkish origin. Our patient is the first reported case of PKAN in Turkey with molecular genetic confirmation of the diagnosis. The frameshift mutation c.821_822delCT of the PANK2 gene detected in our patient has only been described in such classic patients to date, and our case provides further evidence of the association of this mutation with the classic PKAN phenotype. Since this mutation is a rare disease-causing mutation in other populations, further studies of more Turkish PKAN patients will show if it is the result of a founder effect... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538206 Sun, 01 Mar 2009 00:00:00 +0100 2538206 http://www.medworm.com/index.php?rid=2538205&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19480329%26dopt%3DAbstract Authors: Simşek E, Savaş-Erdeve S, Sakamoto O, Doğanci T, Dallar Y Fanconi-Bickel syndrome is a rare inherited disorder of carbohydrate metabolism. The disease is characterized by the association of a massive hepatomegaly due to glycogen accumulation, severe hypophosphatemic rickets and marked growth retardation due to proximal renal tubular dysfunction. Fanconi-Bickel syndrome is a single gene disease and is caused by defects in the facilitative glucose transporter 2 (GLUT2) gene (SLC2A2) on chromosome 3q26.1-26.3, which encodes for the glucose transporter protein 2 expressed in hepatocytes, pancreatic beta-cells, enterocytes, and renal tubular cells. Several mutations in a gene encoding a glucose transporter have been reported in patients with Fanconi-Bickel syndrom... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538205 Sun, 01 Mar 2009 00:00:00 +0100 2538205 http://www.medworm.com/index.php?rid=2538204&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19480330%26dopt%3DAbstract Authors: Armangil D, Canpolat FE, Yiğit S, Demir HA, Ceyhan M Congenital syphilis is the oldest recognized congenital infection and still represents a serious healthcare problem in the 21st century. It is important to be fully informed regarding the early diagnosis and treatment of congenital syphilis to prevent its devastating complications leading to death. In this manuscript, we report a newborn infant with unusual clinical findings of congenital syphilis such as a non-fluctuant mass surrounding the left calf. She did not have any additional system involvement such as hepatic or skin involvement or lymph nodes. To our best knowledge, there are only a few case reports presented with isolated bone involvement. This case demonstrates that congenital syphilis should be considered ... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538204 Sun, 01 Mar 2009 00:00:00 +0100 2538204 http://www.medworm.com/index.php?rid=2538203&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19480331%26dopt%3DAbstract Authors: Keklikçi U, Unlü K, Cakmak A, Akdeniz S, Akpolat N A three-year-old girl presented with a small brown lesion on the right upper eyelid margin. Close examination revealed an insect body attached to the eyelid margin. Microscopic examination of the specimen identified the species of the organism as Ixodes ricinus. The tick was completely removed with blunt forceps. She was treated with lid toilet, irrigation, and application of topical 0.3% ciprofloxacin four times daily to the affected eye. The lesion healed without scarring after one week. No systemic symptoms were observed. Mechanical removal with blunt forceps may be a quick, easy, safe and effective treatment for ticks located on the eyelids. PMID: 19480331 [PubMed - indexed for MEDLINE] (Source: The Turkish J... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538203 Sun, 01 Mar 2009 00:00:00 +0100 2538203 http://www.medworm.com/index.php?rid=2538202&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19480332%26dopt%3DAbstract We report a patient with severe developmental delay, failure to thrive, microbrachycephaly, large anterior fontanel, ocular hypertelorism, broad nasal bridge, low-set ears, long philtrum, micrognathia, partial cleft palate, broad distal digits, abnormal palmar creases, joint contractures, and cardiovascular anomaly. Cytogenetic analysis with high resolution chromosome banding showed an unbalanced karyotype of 46,XX, der(2)t(2;7)(p23;p13) originating from a maternal balanced translocation. Our patient showed a duplication of 7p13-->pter and a deletion of 2p23-->pter. Our analysis suggests that duplication 7p is associated with a recognizable characteristic phenotype. PMID: 19480332 [PubMed - indexed for MEDLINE] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538202 Sun, 01 Mar 2009 00:00:00 +0100 2538202 http://www.medworm.com/index.php?rid=2538201&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19480333%26dopt%3DAbstract This report presents a rare case of isolated suppurative submandibular sialadenitis in a full-term newborn without any risk factors. Possible etiology, diagnosis and management of this uncommon disease are discussed. PMID: 19480333 [PubMed - indexed for MEDLINE] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538201 Sun, 01 Mar 2009 00:00:00 +0100 2538201 http://www.medworm.com/index.php?rid=2538200&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19480334%26dopt%3DAbstract We present the second patient with type 1 DM associated with FMF who also had ATD and CD. PMID: 19480334 [PubMed - indexed for MEDLINE] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538200 Sun, 01 Mar 2009 00:00:00 +0100 2538200 http://www.medworm.com/index.php?rid=2538199&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19480335%26dopt%3DAbstract This report presents two siblings with central cyanosis, growth retardation, mental retardation, microcephaly, dystonia and hypertonia diagnosed as RCM type II. PMID: 19480335 [PubMed - indexed for MEDLINE] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538199 Sun, 01 Mar 2009 00:00:00 +0100 2538199 http://www.medworm.com/index.php?rid=2538198&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19480336%26dopt%3DAbstract Authors: Emre S, Firat Y, Güngör S, Firat AK, Karincaoğlu Y Incontinentia pigmenti (IP) is a rare, X-linked dominant disorder that presents at or soon after birth with characteristic cutaneous signs. The eyes and central nervous system are the next most commonly affected systems. We aimed to describe the ophthalmological, neurological and radiodiagnostic findings of a patient with IP and bilateral retinal detachment. Clinical and laboratory findings of a four-month-old female baby who did not have light fixation and had neurological maturation retardation are presented. Characteristic skin lesions of IP were noted especially at the extremities, bilaterally. On neurological examination, motor and mental maturation were retarded and axial hypotonia was noted. Bilateral re... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538198 Sun, 01 Mar 2009 00:00:00 +0100 2538198 http://www.medworm.com/index.php?rid=2538197&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19480337%26dopt%3DAbstract We report a case presenting with severe intermittent intestinal obstruction, most probably due to enteric nervous system abnormality associated with megacystis and micturition difficulty. Medical treatment consisting of pyridostigmine was very successful in our patient. The clinicopathologic features of this very rare entity and its medical treatment are discussed with a brief review of the etiopathogenesis. PMID: 19480337 [PubMed - indexed for MEDLINE] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538197 Sun, 01 Mar 2009 00:00:00 +0100 2538197 http://www.medworm.com/index.php?rid=2538244&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19378883%26dopt%3DAbstract Authors: Dursun O, Erişir S, Yeşilipek A One hundred and one children with visceral leishmaniasis (VL) who admitted to Akdeniz University Hospital during a 20-year period were analyzed. Median age of the patients was 3 years (range: 5.5 months-13 years). The most common symptoms at presentation were fever, pallor and abdominal distension. Splenomegaly was found in all of the patients while hepatomegaly was present in 98%. Anemia (96%), leukopenia (74%) and thrombocytopenia (56%) were the main laboratory abnormalities. Thirty-three (33%) of the patients were pancytopenic on admission. Bone marrow smear was positive for leishmania in 91% of the patients. Seventy-four patients were treated with antimony +/- pentamidine and 27 with amphotericin B. Three of our patients died bec... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538244 Thu, 01 Jan 2009 00:00:00 +0100 2538244 http://www.medworm.com/index.php?rid=2538243&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19378884%26dopt%3DAbstract Authors: Erol I, Buyan N, Ozkaya O, Sahin F, Beyazova U, Söylemezoğlu O, Hasanoğlu E The urinary calcium/creatinine ratio (UCa/Cr) in spot urine samples has been used extensively for screening and diagnosis of hypercalciuria (HC). The aim of this study was to determine the normal values for UCa/Cr, urinary sodium/creatinine (UNa/Cr), urinary potassium/creatinine (UK/Cr) and urinary sodium/potassium (UNa/K) ratios in healthy Turkish children aged 0-5 years. A total of 425 children were enrolled in the study. The urine samples were obtained from the second morning urine in children after breakfast and the first urine after feeding in infants. Urine Ca, Cr, Na and K levels were studied. A positive correlation was found between the UCa/Cr, UNa/Cr, UK/Cr and UNa/K ratios. O... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538243 Thu, 01 Jan 2009 00:00:00 +0100 2538243 http://www.medworm.com/index.php?rid=2538242&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19378885%26dopt%3DAbstract In conclusion, KC starting 30 minutes before and continuing 10 minutes after an invasive procedure was found to be effective in decreasing pain during and after the invasive procedure in premature infants. PMID: 19378885 [PubMed - indexed for MEDLINE] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538242 Thu, 01 Jan 2009 00:00:00 +0100 2538242 http://www.medworm.com/index.php?rid=2538240&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19378886%26dopt%3DAbstract Authors: Cetinkaya F, Zübarioğlu AU, Göktaş S Severe anaphylactic reactions are medical emergencies in children and require immediate recognition and treatment. Many advances have been reported recently in the treatment of anaphylaxis. Despite this, little is known about whether or not these advances are known by all pediatricians. To evaluate the knowledge of pediatricians on the recent advances in the treatment of anaphylaxis, some pediatricians from istanbul were asked to complete an anonymous questionnaire. A total of 124 pediatricians agreed to participate in the study. Most attendants (92%) knew epinephrine as the first drug in the treatment of anaphylaxis, but more pediatricians (65%) also preferred subcutaneous route as the most effective route for injecti... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538240 Thu, 01 Jan 2009 00:00:00 +0100 2538240 http://www.medworm.com/index.php?rid=2538238&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19378887%26dopt%3DAbstract The objective of this study was to determine the dosing, efficacy and side effects of carvedilol for the management of dilated cardiomyopathy in children. Sixteen children with idiopathic dilated cardiomyopathy, aged 7 months to 138 months and with an ejection fraction less than 40%, were treated with carvedilol. The average initial dose was 0.1 mg/kg/day and it was uptitrated to 0.4 mg/kg/day. After six months on carvedilol, there were improvements in clinical scoring system from an average of 2.94 to 2.50 (p<0.05), in mean fractional shortening from 17.2 +/- 6.1% to 22.7 +/- 5.1% (p<0.05), and in ejection fraction from 35.2 +/- 6.8% to 43.1 +/- 11.2% (p<0.05). No side effect was observed during the study period. Two patients died due to serious infection. Carvedilol in addition ... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538238 Thu, 01 Jan 2009 00:00:00 +0100 2538238 http://www.medworm.com/index.php?rid=2538236&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19378888%26dopt%3DAbstract Authors: Budak F, Nordmann P, Girlich D, Gür D The rate of in vitro resistance to various antimicrobials in 179 consecutive isolates of Salmonella spp., which included serogroups D (109), B (52), C1 (10) and C2 (8) isolated from children, was investigated. Production of extended-spectrum beta-lactamase (ESBL) was studied in ampicillin-resistant isolates. Antimicrobial susceptibilities were determined by disk diffusion tests and by BIOMIC video reader system. Overall resistance rates to ampicillin and amoxicillin/clavulanate were 26.3% and 10.6%, respectively. Resistance to ceftriaxone and ceftazidime was 3.3%. Resistance rates for chloramphenicol, trimethoprim-sulfamethoxazole, ciprofloxacin, amikacin and gentamicin were 40.7%, 31.3%, 2.2%, 2.2% and 6.1%, respectively. beta-lactam... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538236 Thu, 01 Jan 2009 00:00:00 +0100 2538236 http://www.medworm.com/index.php?rid=2538234&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19378889%26dopt%3DAbstract The objective of this meta-analysis was to determine with cross-sectional and cohort trails whether the use of pacifier increases the risk of early weaning from exclusive breastfeeding before six months of age or cessation of breastfeeding from any breastfeeding before 24 months of age. Additionally, the effect of the age for starting pacifier use on breastfeeding duration was analyzed in the cohort trails. The Medline database was searched (1980 to 2006) with "breastfeed, breastfeeding, or breast feed" and "pacifier, dummy, or soother" as individual keywords. Only human studies published in English were included. Unpublished data were not sought. Twelve trials with weaning from exclusive breastfeeding and 19 trials with cessation of any breastfeeding were included in the meta-analysis. Th... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538234 Thu, 01 Jan 2009 00:00:00 +0100 2538234 http://www.medworm.com/index.php?rid=2538232&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19378890%26dopt%3DAbstract In this study, we performed a retrospective review of the records of our pediatric patients with pilomatricoma. We discuss herein the diagnosis and management of this uncommon skin tumor, and compare our experience with the previous literature. Pilomatricoma should be included in the differential diagnosis of superficial pediatric head and neck masses by any physician involved with pediatric tumors. PMID: 19378890 [PubMed - indexed for MEDLINE] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538232 Thu, 01 Jan 2009 00:00:00 +0100 2538232 http://www.medworm.com/index.php?rid=2538230&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19378891%26dopt%3DAbstract Authors: Semiz S, Kurt F, Kurt DT, Zencir M, Sevinç O The relationship between the possible factors affecting pubertal onset and pubertal timing was investigated in the Denizli province in Turkey. A total number of 3311 subjects (1562 girls, 1749 boys) aged 6-16.5 years participated in this study. Body mass index (BMI) was calculated. Pubertal stages were assessed according to methods of Marshall and Tanner. Testicular volume was determined using Prader orchidometer. Menarcheal age was recorded. All parents and students completed different questionnaires on demographic variables affecting pubertal timing such as socioeconomic conditions, psychosocial factors, exercise, nutritional status, chronic diseases, migration and birth weight. Using distribution percentiles of pubertal stag... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538230 Thu, 01 Jan 2009 00:00:00 +0100 2538230 http://www.medworm.com/index.php?rid=2538228&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19378892%26dopt%3DAbstract This study was a cross-sectional research conducted among high school students of Erzurum province (n=536). The level of exhaled CO of all participants who accepted to participate in the study was measured by Microbio CO Analyzer (Microbio Med). Nicotine dependency was measured by a six-item version of the Fagerstrom Tolerance Questionnaire. Mean age of the adolescents was 17.0 +/- 1.6 (median: 17) and 77.1% were male. Of the study population, 30.2% and 11.4% of the students were regular and occasional smokers, respectively. Non-smokers who were exposed to environmental tobacco smoke had significantly (p<0.01) higher exhaled CO levels (2.8 +/- 2.6 ppm) than not-exposed non- smokers (1.8 +/- 1.9 ppm). Only 8.6% of adolescents who reported themselves to be a regular smoker had 7 ppm and h... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538228 Thu, 01 Jan 2009 00:00:00 +0100 2538228 http://www.medworm.com/index.php?rid=2538226&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19378893%26dopt%3DAbstract We present the case of a 20-month-old girl with laryngeal foreign body unrecognized for one year. She was treated for recurrent laryngitis and infectious croup several times. A triangular-shaped, red plastic material with sharp edges was removed from the larynx by direct laryngoscopy. The clinical presentation and management are discussed. PMID: 19378893 [PubMed - indexed for MEDLINE] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538226 Thu, 01 Jan 2009 00:00:00 +0100 2538226 http://www.medworm.com/index.php?rid=2538225&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19378894%26dopt%3DAbstract In this report, we present a 13-year-old boy who developed eyelid anthrax after contact with a sheep carcass during his summer holiday that resulted in eyelid anthrax and cicatricial ectropion. PMID: 19378894 [PubMed - indexed for MEDLINE] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538225 Thu, 01 Jan 2009 00:00:00 +0100 2538225 http://www.medworm.com/index.php?rid=2538224&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19378895%26dopt%3DAbstract Authors: Unal S, Cakir M, Kuşkonmaz B, Cetin M, Tuncer AM There are few therapeutic options in relapsed or refractory acute myeloid leukemia patients. CD33 antigen is expressed on approximately 90% of myeloblasts, and gemtuzumab ozogamicin, as a monoclonal antibody directed against the CD33 surface antigen, may be a good target for these patients. Herein, we present a 15-year-old acute myeloid leukemia patient who was resistant at relapse and could achieve remission with gemtuzumab ozogamicin at a total dose of 9 mg/m2, divided into three doses and delivered to hematopoietic stem-cell transplantation; however, the patient relapsed in a short time without application of transplantation. PMID: 19378895 [PubMed - indexed for MEDLINE] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538224 Thu, 01 Jan 2009 00:00:00 +0100 2538224 http://www.medworm.com/index.php?rid=2538223&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19378896%26dopt%3DAbstract We report a previously healthy eight-year-old boy who presented with acute hemiplegia and obsessive-compulsive disorder secondary to a lesion in lentiform nuclei associated with a history of recent varicella infection. The child was treated with sertraline for obsessive-compulsive disorder symptoms and made a full recovery. PMID: 19378896 [PubMed - indexed for MEDLINE] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538223 Thu, 01 Jan 2009 00:00:00 +0100 2538223 http://www.medworm.com/index.php?rid=2538222&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19378897%26dopt%3DAbstract We report here two children with AHS due to phenytoin. Both cases were under treatment with phenytoin: the first case was a seven-year-old boy who was referred with the classic form of AHS. The second patient was a five-year-old girl who manifested with DRESS. The manifestations in both cases improved after withholding the phenytoin. Clinical presentations of adverse drug reactions are highly variable and must therefore be suspected in any patient who develops any unusual manifestation after taking antiepileptic drugs. Early recognition of AHS and withholding and/or changing the medication are necessary to prevent potentially fatal outcomes. PMID: 19378897 [PubMed - indexed for MEDLINE] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538222 Thu, 01 Jan 2009 00:00:00 +0100 2538222 http://www.medworm.com/index.php?rid=2538221&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19378898%26dopt%3DAbstract We present a case with PPB type II successfully treated with complete surgical resection following neoadjuvant chemotherapy. She has been free of disease for 33 months of follow-up. Complete surgical resection of the tumor at the time of diagnosis is the cornerstone of PPB management, but in the majority of patients, initial surgery is incomplete because a large tumor may involve vital structures. For this reason, patients with initially unresectable tumors should be treated with neoadjuvant chemotherapy to reduce the lesion to the point that it becomes resectable. PMID: 19378898 [PubMed - indexed for MEDLINE] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538221 Thu, 01 Jan 2009 00:00:00 +0100 2538221 http://www.medworm.com/index.php?rid=2538220&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19378899%26dopt%3DAbstract Authors: Güneş D, Mutafoğlu-Uysal K, Sarialioğlu F, Cakmakçi H, Olgun N Aneurysmal bone cyst is a rare benign tumor of the bone that can be difficult to distinguish from malignant tumors, especially when it presents in an unusual location. Herein, we report a six-year-old girl with a primary aneurysmal bone cyst in an uncommon location. It originated from the 4th rib and she presented with a huge chest wall mass. Despite the large size of the cyst, the only symptom was persistent cough. She was successfully treated with total excision of tumor without any complication. The patient has been followed up for 56 months without any recurrence. PMID: 19378899 [PubMed - indexed for MEDLINE] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538220 Thu, 01 Jan 2009 00:00:00 +0100 2538220 http://www.medworm.com/index.php?rid=2538219&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19378900%26dopt%3DAbstract Authors: Akgül S, Küpeli S, Yalçin B, Demir HA, Büyükpamukçu M Herpes zoster is a painful neurocutaneous disease caused by the reactivation of the varicella zoster virus, and it can develop any time after a primary infection, which usually occurs during childhood. A variety of immunocompromised patient populations are known to be at increased risk for herpes zoster. Postherpetic pruritus is a serious complication, which may last after the infection, and has the potential to cause injury and disability. The medical literature on postherpetic pruritus is very limited. This is a case report of a six-year-old child who developed postherpetic pruritus lasting three months, which responded to topical urea treatment. PMID: 19378900 [PubMed - indexed for MEDLI... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538219 Thu, 01 Jan 2009 00:00:00 +0100 2538219 http://www.medworm.com/index.php?rid=2538218&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19378901%26dopt%3DAbstract We present a female infant with facial abnormalities such as bilateral cleft lip and palate, ectrodactyly and central diabetes insipidus. She had a history of recurrent hypernatremic attacks and she was treated successfully with oral desmopressin. As an alternative to the nasal route, long-term management was achieved using oral route and she had a favorable growth and development during infancy. PMID: 19378901 [PubMed - indexed for MEDLINE] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538218 Thu, 01 Jan 2009 00:00:00 +0100 2538218 http://www.medworm.com/index.php?rid=2538217&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19378902%26dopt%3DAbstract Authors: Eren M, Celik M, Kinik S, Arda IS Hirschsprung disease, the colonization defect of neural crest cells through the colon, is one of the reasons for functional obstruction in neonates. Furthermore, hypothyroidism has been known to be one of the causes of bowel hypomotility and pseudoobstruction. These two diseases are generally considered in the differential diagnosis. Although defective thyroid function has been found to be responsible for inappropriate neuronal migration in the brain, the effect of thyroid hormone on neural crest cell migration to the bowel has not yet been evaluated. Here, we report a case with Hirschsprung disease and congenital hypothyroidism, which may point to the need for future studies evaluating the interaction of colonic neural crest cell colonization... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2538217 Thu, 01 Jan 2009 00:00:00 +0100 2538217 http://www.medworm.com/index.php?rid=2056469&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19093320%26dopt%3DAbstract Authors: PMID: 19093320 [PubMed - indexed for MEDLINE] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=2056469 Mon, 22 Dec 2008 10:47:34 +0100 2056469 http://www.medworm.com/index.php?rid=1975975&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19014041%26dopt%3DAbstract Authors: Kalayci O, Yorgancioğlu A, Kalyoncu F, Khaltaev AN, Bousquet J PMID: 19014041 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1975975 Tue, 01 Jul 2008 04:00:00 +0100 1975975 http://www.medworm.com/index.php?rid=1975974&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19014042%26dopt%3DAbstract Authors: Küçüker H Children- and adolescent-oriented sexual crime has been a progressively increasing public health problem in Turkey. The aim of this study was to define the sociodemographic features of the sexual assault victims and the assailants in the crimes against children and adolescents. In 221 (82.4%) of the cases, perineal findings were detected. In addition to perineal trauma, 76 (28.4%) of the victims had general body trauma and 35 (13.1%) declared fire-arm or knife threat. Ninety-nine (36.9%) assaults happened at the victim's home while 74 (27.6%) events took place in the assailant's home. Eighty-nine (33.2%) of the cases were examined by a general practitioner, 179 (66.8%) by a gynecologist or by a general surgeon (for male subjects), and 40 (14.9%) by for... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1975974 Tue, 01 Jul 2008 04:00:00 +0100 1975974 http://www.medworm.com/index.php?rid=1975973&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19014043%26dopt%3DAbstract This study was undertaken to describe the pattern of pediatric trauma in a multi-center hospital-based study. Pre-hospital and hospital data were prospectively gathered on all hospitalized trauma patients admitted to six major trauma hospitals in Tehran from August 1999 to September 2000. Data from patients 12 years of age and younger were analyzed for this article. About 15.1% of the hospitalized trauma cases belonged to children. Mean age was 7.35 +/- 3.25 years and 69.1% of cases were male. Most of the cases were injured accidentally. More than half of the cases were injured due to falls, followed by road traffic accidents. Injuries in streets were the most common, followed by injuries at home. Recently, several injury prevention strategies have been designed and developed in Iran, and ... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1975973 Tue, 01 Jul 2008 04:00:00 +0100 1975973 http://www.medworm.com/index.php?rid=1975972&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19014044%26dopt%3DAbstract Authors: Ergüven M, Emeksiz C, Deveci M, Ozlü SG We aimed to investigate the urinary microalbumin level, which is a sensitive marker of glomerular function for establishing probable renal involvement in early stages of the disease in patients with familial Mediterranean fever (FMF), and to determine the relation between gene mutations of these cases and urinary microalbumin levels. Fifty patients with FMF who were admitted to our department and had been followed up in the pediatric rheumatology outpatient clinic for five years were included in the study. Diagnosis was based on Tel-Hashomer criteria. Gene mutations (M694V, V726A, M680I) and acute phase reactants were determined as supportive findings. Routine renal function tests with 24 hour urinary microalbumin levels and ur... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1975972 Tue, 01 Jul 2008 04:00:00 +0100 1975972 http://www.medworm.com/index.php?rid=1975971&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19014045%26dopt%3DAbstract Authors: Darendeliler F, Baş F, Gökçe M, Poyrazoğlu S, Sükür M, Bundak R, Saka N, Günöz H The aim of this study was to analyze head circumference (HC) growth retrospectively in longitudinally followed growth hormone (GH)-deficient children on GH therapy. Data of 54 (25 F, 29 M) children with GH deficiency were analyzed by dividing the children into two groups: Group 1 with height age (HA) < or =5 years (yrs) (n:18) and Group 2 with HA >5 yrs (n:36). Anthropometric measurements were expressed as standard deviation score (SDS) for chronological age (CA), and HC was also expressed as SDS for CA and HA. Group 1, with CA 6.6 (2.9) yrs at onset of therapy, showed an increase in height SDS from -3.8 (1.4) to -2.4 (1.7) (p < 0.001) and in HC S... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1975971 Tue, 01 Jul 2008 04:00:00 +0100 1975971 http://www.medworm.com/index.php?rid=1975970&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19014046%26dopt%3DAbstract Authors: Yalçin S, Ciftçi AO, Karaağaoğlu E, Haliloğlu M, Senocak ME, Tanyel FC, Büyükpamukçu N In this research, we aimed to evaluate the accordance of radiologic study results with each other and with surgical findings with regard to presence and/or absence of intussusception. One hundred and seventy-nine patients treated for intussusception between 1993 and 2003 inclusive were retrospectively reviewed to compare results of initial ultrasonography, colonography, followup ultrasonography after conservative management (reduction with barium enema and/or air insufflation) and surgical findings to determine their accordance within each other with regard to diagnosis of intussusception. Results of initial ultrasonography were not in accordance wi... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1975970 Tue, 01 Jul 2008 04:00:00 +0100 1975970 http://www.medworm.com/index.php?rid=1975969&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19014047%26dopt%3DAbstract In this study, 32 patients under the age of 17 years with acquired aplastic anemia (AAA) were evaluated. Nine patients developed AAA associatedwith viral infection in which viral hepatitis and varicella infection were nearly equal. Four of the patients were administered drugs before developing AAA. Patients were treated as follows: combined immunosuppressive therapy (CIST) including anti-thymocyte or anti-lymphocyte globulin plus high-dose methylprednisolone (HDMP) and cyclosporin A and granulocyte colony-stimulating factor (G-CSF) (14 patients); mega-dose (30 mg/kg) methylprednisolone (8 patients); and HDMP combined with cyclosporin A or anapolon or cyclophosphamide (6 patients). Complete remission was seen in 10 patients and partial remission in 2 patients. The response rate was similar ... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1975969 Tue, 01 Jul 2008 04:00:00 +0100 1975969 http://www.medworm.com/index.php?rid=1975968&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19014048%26dopt%3DAbstract Authors: Alborzi A, Aelami MH, Astaneh B, Pourabbas B, Farshad S, Kalani M, Nasiri J, Rashidi M Escherichia coli (E. coli) O157:H7 is a common cause of bloody diarrhea in developed countries. The aim of this study was to determine whether E. coli O157:H7 is a possible pathogen of bloody diarrhea in southern Iran. Out of 719 children with diarrhea, 243 (34%) patients with positive occult blood took part in our study. The polyclonal antibody test and polymerase chain reaction (PCR) were used to identify E. coli O157:H7. Stool cultures showed enteropathogens in 107 patients (44%). Shigella (34.3%) was followed by E. coli (8.6%), campylobacter (2%) and salmonella (0.4%). None of the E. coli species was of O157:H7 serotype. Antibiotic sensitivity of shigella species was 100% to ceftriaxone,... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1975968 Tue, 01 Jul 2008 04:00:00 +0100 1975968 http://www.medworm.com/index.php?rid=1975967&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19014049%26dopt%3DAbstract Authors: Cultu O, Yildirim I, Ceyhan M, Korkmaz A, Yurdakök M, Karaağaoğlu E, Seçmeer G While planning medical care, health care workers must consider the body temperature changes as measured by the mothers on most occasions. We evaluated the reliability of three different temperature measurement methods when they were used by the mothers by comparing with the measurements taken by the pediatrician. In this prospective study, body temperatures of 50 healthy newborns during their 2nd day of life were measured by mothers and one physician with mercury-in-glass (MG), digital mercury (DM) and infrared tympanic membrane thermometers (ITMT). Measurements by the mothers and the physician were correlated for the three different methods. The effects of the educational leve... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1975967 Tue, 01 Jul 2008 04:00:00 +0100 1975967 http://www.medworm.com/index.php?rid=1975966&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19014050%26dopt%3DAbstract Authors: Cizmecioğlu FM, Hatun S, Kalaça S There is no consensus on whether or not the diagnostic criteria of metabolic syndrome (MS) defined for adults [National Cholesterol Education Panel (NCEP) and World Health Organization (WHO)] can be used in childhood as well. We aimed to compare prevalence of metabolic syndrome among obese children and adolescents using WHO and NCEP guidelines. A total of 112 obese children and adolescents were assessed. MS was diagnosed according to both modified WHO and NCEP criteria using cut-off values for children. Abnormal glucose homeostasis was identified in 46.6% of the subjects. Fasting glucose levels for all subjects were less than 110 mg/dl and no subjects had type 2 diabetes. Overall, dyslipidemia was present in 42.9% and hypertension i... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1975966 Tue, 01 Jul 2008 04:00:00 +0100 1975966 http://www.medworm.com/index.php?rid=1975965&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19014051%26dopt%3DAbstract In this study, we evaluated the experience of a single center pediatric intensive care unit in pediatric bedside tracheostomies performed during a six-year period. Thirty-one bedside tracheostomies were performed on 31 patients aged 2 months to 18 years. The major indication for tracheostomy was prolonged ventilator dependence. Twenty-two complications, 6 major and 16 minor, were observed in 18 patients. Early complications were observed in 5 patients and all were managed immediately without serious outcomes. Ten patients died during the study period and only one death was directly related to the tracheostomy; the remaining 9 patients died due to their underlying disease. Eleven patients were successfully decannulated, 12 patients were discharged home with their tracheostomies and 5 of the... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1975965 Tue, 01 Jul 2008 04:00:00 +0100 1975965 http://www.medworm.com/index.php?rid=1975964&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19014052%26dopt%3DAbstract We present a case of osteoid osteoma with delayed diagnosis that presented itself with neurological signs. Prominent features present in the patient included pain that responded well to medication and muscle atrophy, which led to a wider differential diagnosis. Diagnosis was made approximately two years after the onset of his initial symptoms, after having been investigated and treated both in our own hospital and elsewhere. This case illustrates clinical and radiological diagnostic problems of osteoid osteoma, demonstrating that it can present itself with neurological signs. Correct diagnosis then requires detailed history and clinical awareness. PMID: 19014052 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1975964 Tue, 01 Jul 2008 04:00:00 +0100 1975964 http://www.medworm.com/index.php?rid=1975963&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19014053%26dopt%3DAbstract We report an infant with unexplained fractures from the right 3rd rib through to the 8th rib who had undergone resection of a large cervical tumor and had been admitted to a neonatal intensive care unit. Neither trauma nor bone fragility disease was found in the patient during the detailed investigation conducted by the Malpractice Investigative Committee. PMID: 19014053 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1975963 Tue, 01 Jul 2008 04:00:00 +0100 1975963 http://www.medworm.com/index.php?rid=1975962&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19014054%26dopt%3DAbstract In this report, we present our experience in a 36-month-old child with relapse of HSV encephalitis after 14-day acyclovir therapy. A 36-month-old boy who was presented with deterioration in speech and motor functions and fluctuation of consciousness was treated with acyclovir for 14 days for HSV encephalitis. He was discharged since his cerebrospinal fluid findings returned to normal range and clinical improvement was seen. Ten days later, he was readmitted to our clinic with acute fever, focal convulsions and choreoathetoid movements, and altered consciousness. Acyclovir was started immediately, but he died on the 17th day because of respiratory failure. Relapses due to HSV encephalitis are rare and limited to a small number of case reports in the literature. Persistence of HSV, detection... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1975962 Tue, 01 Jul 2008 04:00:00 +0100 1975962 http://www.medworm.com/index.php?rid=1975961&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19014055%26dopt%3DAbstract We report a 16-year-old boy with cystic fibrosis presenting with meconium ileus in the neonatal period who showed mild clinical phenotype later. He had sufficient pancreatic function, mild lung involvement and borderline sweat chloride levels. Analysis of the cystic fibrosis transmembrane regulator protein gene revealed the rare mutation: 2183AA-G/D1152H. To our knowledge, this is the first report concerning such a mutation combination in cystic fibrosis. PMID: 19014055 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1975961 Tue, 01 Jul 2008 04:00:00 +0100 1975961 http://www.medworm.com/index.php?rid=1975960&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19014056%26dopt%3DAbstract We report a one-month-old infant with HPS with a 15-year-old sister with Bartter syndrome. The infant's birth weight was 2750 g and she had severe dehydration on the 2nd day of life. She had hypercalcemia, hyponatremia, hypokalemia, metabolic alkalosis and elevated plasma renin and aldosterone levels. We instituted indomethacin therapy accompanied by steroid therapy for hypercalcemia. However, the patient developed abdominal distention on the 30th day, which was due to diffuse pneumatosis in sigmoid colon revealed by a subsequent surgical intervention. Following surgery, the patient developed fever, electrolyte abnormalities and subsequently sepsis. The patient died due to sepsis 10 days after surgery. We conclude that indomethacin and steroid therapy must be used cautiously in infants wit... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1975960 Tue, 01 Jul 2008 04:00:00 +0100 1975960 http://www.medworm.com/index.php?rid=1975959&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19014057%26dopt%3DAbstract Authors: Büyüktortop N, Gürbüz-Köz O, Atalay T, Kural G Horner syndrome, consisting of ipsilateral miosis, upper eye lid ptosis, and facial anhidrosis, has been reported as a rare complication of internal jugular vein catheterization. In this paper, we describe a nine-year-old girl presenting with postganglionic Horner syndrome, in whom right-sided ptosis and miosis occurred after ipsilateral percutaneous internal jugular venous catheterization. PMID: 19014057 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1975959 Tue, 01 Jul 2008 04:00:00 +0100 1975959 http://www.medworm.com/index.php?rid=1975958&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19014058%26dopt%3DAbstract In this report, we present a 24-week-old female fetus with a possible prenatal diagnosis of thanatophoric dysplasia in whom postmortem examination revealed lethal type Larsen-like syndrome associated with bifid tongue, severe micrognathia and non-immune hydrops fetalis. These findings have not been reported previously in the lethal type Larsen syndrome. PMID: 19014058 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1975958 Tue, 01 Jul 2008 04:00:00 +0100 1975958 http://www.medworm.com/index.php?rid=1975957&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19014059%26dopt%3DAbstract We describe two cases of chronic massive fetomaternal hemorrhage with favorable outcome. During the follow-up, both infants showed late-onset neutropenia, which was not previously reported in healthy, growing infants with history of massive FMH. PMID: 19014059 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1975957 Tue, 01 Jul 2008 04:00:00 +0100 1975957 http://www.medworm.com/index.php?rid=1975956&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19014060%26dopt%3DAbstract We report the case of a preterm neonate who developed severe sepsis on the 28th day of life, who was successfully treated with the inactivated form of protein C for a period of 96 hours. PMID: 19014060 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1975956 Tue, 01 Jul 2008 04:00:00 +0100 1975956 http://www.medworm.com/index.php?rid=1975955&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19014061%26dopt%3DAbstract Authors: Narchi H, Basak R A child presented with features of bacterial tracheitis with complete response to therapy. He presented with a recurrence one week later. A foreign body in the tracheal wall was diagnosed and removed by bronchoscopy. Tracheal intubation for airway management and tracheal toileting are not enough in bacterial tracheitis; bronchoscopy should be considered to diagnose any underlying cause. PMID: 19014061 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1975955 Tue, 01 Jul 2008 04:00:00 +0100 1975955 http://www.medworm.com/index.php?rid=1975954&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D19014062%26dopt%3DAbstract Guillain-Barré syndrome in an immunocompromised patient with Wiskott-Aldrich syndrome. Turk J Pediatr. 2008 Jul-Aug;50(4):412-3 Authors: Olmez A, Turul T, Tezcan I, Turanli G PMID: 19014062 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1975954 Tue, 01 Jul 2008 04:00:00 +0100 1975954 http://www.medworm.com/index.php?rid=1775897&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18773663%26dopt%3DAbstract In conclusion, although most of the preterm SGA children show CUG, they reach a compromised height in childhood. A number of preterm AGA children show a catch-down growth. PMID: 18773663 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1775897 Thu, 01 May 2008 04:00:00 +0100 1775897 http://www.medworm.com/index.php?rid=1775896&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18773664%26dopt%3DAbstract Authors: Devrim I, Kanra G, Kara A, Cengiz AB, Orhan M, Ceyhan M, Seçmeer G The infection of the orbita and ocular tissues can result in severe local and systemic complications. We aimed to determine the predisposing factors for preseptal and orbital cellulitis, the clinical and routine laboratory differences between orbital and preseptal cellulitis, and the change in the spectrum of the pathogens and the antibiotics used in the last 10 years. One hundred thirty-nine patients, hospitalized in Hacettepe University Faculty of Medicine Children's Hospital between 1 January 1990 and 31 December 2003 with diagnosis ofperiorbital or orbital cellulitis, were reviewed retrospectively. Ten of the patients (7%) had orbital and 129 (93%) had preseptal cellulitis. The male/female ratio was 1.... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1775896 Thu, 01 May 2008 04:00:00 +0100 1775896 http://www.medworm.com/index.php?rid=1775895&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18773665%26dopt%3DAbstract Authors: Kanbur N, Mesci L, Derman O, Turul T, Cuhadaroğlu F, Kutluk T, Tezcan I Tumor necrosis factor alpha (TNF-alpha) is a principal cytokine that may induce weight loss. TNF-alpha -308 G to A polymorphism increases transcription of TNF-alpha in vitro. The aim of this study was to investigate whether TNF-alpha gene promoter polymorphism at position -308 (G to A substitution) is one of the factors playing a role in the development of anorexia nervosa (AN). Sixteen patients with AN, aged 11-20 years, were included in this study, and 5/16 (31%) patients had TNF-alpha -308 G/A genotype. In the control group, 12/174 (7%) had -308 G/A genotype. There was a significant statistical difference between the patient and control groups (p=0.007). The minimum body mass index (BMI) values ev... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1775895 Thu, 01 May 2008 04:00:00 +0100 1775895 http://www.medworm.com/index.php?rid=1775894&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18773666%26dopt%3DAbstract Authors: Ekici F, Tutar E, Atalay S, Arsan S, Ozçelik N The aim of this study was to evaluate the incidence and spontaneous closure rate of ventricular septal defects in a randomly selected newborn population, using color flow Doppler echocardiographic screening. Color flow Doppler echocardiographic screening was performed in 1075 neonates within the first 72 hours of life. We also followed-up patients with ventricular septal defect for a year to detect spontaneous closure rate and its timing. The incidences of ventricular septal defect in all neonates, preterm neonates and term neonates were found as 47.4/1,000, 56/1,000 and 46.3/1,000 live births, respectively. All patients with ventricular septal defect except one were asymptomatic. Forty-six cases had a trabecular and five cas... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1775894 Thu, 01 May 2008 04:00:00 +0100 1775894 http://www.medworm.com/index.php?rid=1775893&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18773667%26dopt%3DAbstract Authors: Tezer H, Seçmeer G, Kara A, Ceyhan M, Cengiz AB, Devrim I, Us D, Yüce A, Gürakan F, Yildirim I, Ozen H, Saltik-Temizel IN Ganciclovir treatment in children with cytomegalovirus (CMV) infection is still controversial and only indicated in selected cases. The aim of thi study was to evaluate clinical and demographic features of CMV hepatitis in immunocompetent children and to determine the effect of ganciclovir treatment in these patients retrospectively. The study was carried out in a group o 29 children with CMV hepatitis. All the patients were investigated for signs of infection, inborn errors of metabolism, genetic diseases, extrahepatic biliary atresia and other causes of hepatitis. Two patients with congenital CMV infection and two patients with biliary atre... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1775893 Thu, 01 May 2008 04:00:00 +0100 1775893 http://www.medworm.com/index.php?rid=1775892&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18773668%26dopt%3DAbstract Authors: Yarar C, Yakut A, Akin A, Yildiz B, Dinleyici EC The aim of this study was to make a retrospective descriptive analysis of the features of children with acute carbon monoxide poisoning (COP). We evaluated 74 children (43 girls, 31 boys; age range 1 to 17.8 years) who were consecutively admitted to our emergency unit and hospitalized with accidental acute COP between June 2003 and June 2005. All patients received normobaric oxygen therapy until their carboxyhemoglobin (COHb) levels were decreased below 2% and their symptoms resolved. Thirty-eight of 74 patients (51.4%) also received hyperbaric oxygen (HBO) therapy as indicated by signs and symptoms or COHb levels. COHb levels were significantly higher and hospitalization period was longer in the children who had abnormal neurol... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1775892 Thu, 01 May 2008 04:00:00 +0100 1775892 http://www.medworm.com/index.php?rid=1775891&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18773669%26dopt%3DAbstract Authors: Esme H, Doğru O, Eren S, Korkmaz M, Solak O The aim of this study was to present our experience in management of neonatal pneumothorax and factors contributing to persistent pneumothorax and mortality. Forty-two newborns were analyzed according to gestational age, birth weight, Apgar score, age of admittance, type of delivery, mother's age, side of pneumothorax, causes of pneumothorax, accompanying disorders, tube thoracostomy and mechanical ventilation durations, mean hospital stay, and deaths. Sixteen patients (38%) weighed less than 2500 g and 28 (66%) were preterm. The mean Apgar score at 5th minute was 6.2 (2-10). The pneumothorax was bilateral in 9 patients (21%). There was a defined underlying lung pathology in 26 (61%) patients and accompanying disorder in 14 (33... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1775891 Thu, 01 May 2008 04:00:00 +0100 1775891 http://www.medworm.com/index.php?rid=1775890&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18773670%26dopt%3DAbstract Authors: Khodapanahandeh F, Khosravi N, Larijani T Intraventricular hemorrhage (IVH) is an important cause of morbidity and mortality in very low birth weight (VLBW) infants; 80-90% of cases occur between birth and the third day of life. In a retrospective case control clinical study, files of all premature infants with birth weights <1500 grams admitted between April 2004 and October 2005 to the Neonatal Intensive Care Unit (NICU) of Akbar Abadi Hospital were reviewed. We determined risk factors that predispose to the development of high-grade IVH (grades 3 and 4) in VLBW infants. Thirty-nine infants with IVH grade 3 and 4 were identified. A control group of 82 VLBW infants were also selected. Prenatal data, delivery characteristics, neonatal course data and reports of cranial ultr... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1775890 Thu, 01 May 2008 04:00:00 +0100 1775890 http://www.medworm.com/index.php?rid=1775889&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18773671%26dopt%3DAbstract Authors: Rendón-Macías ME, Villasís-Keever MA, Castañeda-Muciño G, Sandoval-Mex AM In order to determine the accuracy of serum gamma-glutamyl transferase (GGT) as a test for biliary atresia, we reviewed the charts of 29 infants with cholestatic jaundice less than one year of age. All patients underwent liver biopsy or laparotomy with cholangiogram to establish neonatal hepatitis (NH) or extrahepatic biliary atresia (EHBA). We also gathered information from 176 patients from published studies. Sensitivity, specificity, and likelihood ratios (LR) were calculated with 95% confidence interval (95% CI). GGT levels of the EHBA group were higher than those from the NH group. For diagnosis of EHBA at a cut-off level >250 U/L, sensitivity was 83.3% (95% CI, 55.2- 95.... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1775889 Thu, 01 May 2008 04:00:00 +0100 1775889 http://www.medworm.com/index.php?rid=1775888&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18773672%26dopt%3DAbstract In conclusion, PVCs in normal children have benign prognosis and during follow-up a considerable percent show improvement. PMID: 18773672 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1775888 Thu, 01 May 2008 04:00:00 +0100 1775888 http://www.medworm.com/index.php?rid=1775887&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18773673%26dopt%3DAbstract We report on a six-year-old boy with typical Rubinstein-Taybi syndrome (RSTS) phenotype. Clinical findings included mental and motor retardation, patent ductus arteriosus (PDA), undescended testes, hirsutism, broad thumbs with radial angulation and broad toes, and inguinal hernia. His karyotype was normal (46, XY) and fluorescence in situ hybridization (FISH) showed no deletion of the CREBBP [cAMP response element-binding (CREB) binding protein] gene on chromosome 16p13.3. CREBBP gene sequencing also revealed normal results. We wish to present this case because this patient had typical RSTS phenotype, but normal FISH and CREBBP gene sequencing results. It could be possible that genetic heterogeneity is related with novel mutations in other genes. With the publication of such cases, their s... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1775887 Thu, 01 May 2008 04:00:00 +0100 1775887 http://www.medworm.com/index.php?rid=1775886&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18773674%26dopt%3DAbstract Authors: Oka Y, Asabe K, Shirakusa T, Nabeshima K We herein present a megacystis-microcolon-intestinal hypoperistalsis syndrome (MMIHS) case followed by ultrasound (US) examinations before birth. During the prenatal US examination of a 34-year-old woman, an enlarged bladder with bilateral hydronephrosis and hydroureter of the fetus were detected. The amniotic fluid was normal in the second trimester but polyhydramnios was observed in the third trimester. A female baby was born by cesarian section weighing 2632 g. Imaging studies detected an enlarged bladder with bilateral hydronephrosis, hydroureter and microcolon. Laparotomy on the 9th day confirmed a short small bowel with caliber change and the existence of ganglion cells and plexus of the nerve in the intestine. These findings corr... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1775886 Thu, 01 May 2008 04:00:00 +0100 1775886 http://www.medworm.com/index.php?rid=1775885&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18773675%26dopt%3DAbstract Authors: Yildirim SV, Kale-Cekinmez E, Ozcan D, Derbent M Cardiofaciocutaneous (CFC) syndrome is a rare disorder characterized by psychomotor and growth retardation, a typical facial dysmorphism, congenital heart defects, and ectodermal abnormalities. Pulmonic stenosis, atrial and ventricular septal defects, patent ductus arteriosus, and hypertrophic cardiomyopathy are cardiac findings identified in patients with this syndrome; however, tetralogy of Fallot has never been associated with CFC syndrome. CFC should be considered in patients with skin abnormalities in addition to phenotypic features and a congenital heart defect, including tetralogy of Fallot. PMID: 18773675 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1775885 Thu, 01 May 2008 04:00:00 +0100 1775885 http://www.medworm.com/index.php?rid=1775884&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18773676%26dopt%3DAbstract Authors: Güneş D, Mutafoğlu-Uysal K, Canda T, Saydam S, Cemeroğlu AP, Olgun N Juvenile hypertrophy of the breast (JHB) is an uncommon, benign disorder and typically occurs in peri-pubertal females. The etiology ofJHB is uncertain. It may represent an end-organ hypersensitivity of the breast to normal levels of sex steroids. Clinically, it is characterized by rapid enlargement of breasts, either unilateral or bilateral. The definitive diagnosis is made by histopathologic examination. Treatment recommendations include surgery and hormonal therapy, although hormonal manipulation is still controversial in pediatric patients. Here we report a 13-year-old girl with unilateral JHB who did not require surgery or medical treatment. PMID: 18773676 [PubMed - in process]... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1775884 Thu, 01 May 2008 04:00:00 +0100 1775884 http://www.medworm.com/index.php?rid=1775883&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18773677%26dopt%3DAbstract Authors: Hsieh CT, Chiang YH, Tsai WC, Sheu LF, Liu MY Primary extraosseous Ewing sarcoma is a rare entity, especially in the spinal epidural site. Less than 20 cases have been reported in the literature. Here, we present a previously healthy 12-year-old boy who complained of low back pain, progressive gait disturbance and weakness of right lower extremity for nearly one month before admission. Magnetic resonance imaging showed one solitary posterior extradural mass, measuring 4 x 2.2 x 2.1 cm, with severe cord compression at the level from T7 to T9. The mass appeared hypo-intense on both T1-weighted and T2-weighted images and homogeneous contrast enhancement after injection of gadolinium. He underwent laminectomies of T8 and T9 and complete resection of the tumor. The pathology confir... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1775883 Thu, 01 May 2008 04:00:00 +0100 1775883 http://www.medworm.com/index.php?rid=1775882&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18773678%26dopt%3DAbstract Authors: Utine GE, Alanay Y, Aktaş D, Talim B, Kale G, Tunçbilek E Pseudo-trisomy 13 is defined in chromosomally normal patients with holoprosencephaly and associating features suggestive of trisomy 13. An autosomal recessive pattern of inheritance for this situation is most likely, but a gene for this condition has not yet been mapped. A fetus is presented with phenotypic features reminiscent of trisomy 13 but a normal karyotype, 46, XY. The pregnancy was terminated due to severe fetal malformations. In autopsy, the fetus had semilobar holoprosencephaly, hydrocephaly and dysmorphic features such as hypotelorism, cleft lip, a flat nose with a single nostril, low-set ears, postaxial polydactyly in all extremities, left unilateral pes equinovarus and pulmonary segmentation def... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1775882 Thu, 01 May 2008 04:00:00 +0100 1775882 http://www.medworm.com/index.php?rid=1775881&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18773679%26dopt%3DAbstract Ménétrier's disease and severe gastric ulcers associated with cytomegalovirus infection in an immunocompetent child: a case report. Turk J Pediatr. 2008 May-Jun;50(3):291-5 Authors: Canan O, Ozçay F, Bilezikçi B In pediatric patients, Ménétrier's disease is an uncommon clinical entity that has been rarely described only as sporadic cases, and the etiology is unclear. These patients usually have a self-limiting clinical course. Cytomegalovirus is an important pathogen in the immunocompromised host. However, cytomegalovirus infection can be detected in non-immunocompromised children. We discuss the possible role of cytomegalovirus infection in both Menetrier's disease and severe gastric ulcers in an immunocompetent child. PMID: 18773679 [PubMed -... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1775881 Thu, 01 May 2008 04:00:00 +0100 1775881 http://www.medworm.com/index.php?rid=1775880&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18773680%26dopt%3DAbstract Authors: Soyer T, Ozgün-Arli A, Oztürk H, Kaya IS Acute gastric volvulus in the newborn period is a rare condition requiring surgery. The association of gastric volvulus with congenital bands is extremely rare and unreported previously. A one-day-old male neonate was diagnosed to have acute gastric obstruction in the neonatal intensive care unit. Mesenteroaxial gastric volvulus due to dense gastrocolic bands was detected during laparotomy. Band excision and anterior gastropexy were performed. The clinical features, radiologic findings, treatment modes and possible mechanisms of gastric volvulus due to congenital bands are discussed. PMID: 18773680 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1775880 Thu, 01 May 2008 04:00:00 +0100 1775880 http://www.medworm.com/index.php?rid=1775879&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18773681%26dopt%3DAbstract This report describes late diagnosis of a congenital proximal fistula in a 14-year-old girl who underwent surgical repair of a congenital esophageal atresia with distal tracheoesophageal fistula on her first day of life and suffered recurrent bouts of lower airway infections and chronic cough, with the diagnosis of asthma in later childhood. PMID: 18773681 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1775879 Thu, 01 May 2008 04:00:00 +0100 1775879 http://www.medworm.com/index.php?rid=1775878&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18773682%26dopt%3DAbstract We report a case of GCS related with EBV infection without any systemic symptoms in a two-year-old male patient who presented with symmetric red papular eruptions on the cheeks, buttocks and both upper and lower extremities. PMID: 18773682 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1775878 Thu, 01 May 2008 04:00:00 +0100 1775878 http://www.medworm.com/index.php?rid=1775877&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18773683%26dopt%3DAbstract Authors: Corapçioğlu F, Mutlu H, Deveci M PMID: 18773683 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1775877 Thu, 01 May 2008 04:00:00 +0100 1775877 http://www.medworm.com/index.php?rid=1775876&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18773684%26dopt%3DAbstract Authors: Ozsoylu S PMID: 18773684 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1775876 Thu, 01 May 2008 04:00:00 +0100 1775876 http://www.medworm.com/index.php?rid=1671955&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18664071%26dopt%3DAbstract Authors: Yalçinkaya F, Keith R Auditory processing disorders (APD) are defined as difficulties in hearing and understanding speech in the presence of normal peripheral hearing. Children with APD appear to be uncertain about what they hear, and have difficulties listening in background noise, following oral instructions, and understanding rapid or degraded speech. Suspicious behaviors include: "not listening", "unable to follow direction", or "unable to learn from information they hear". These children are often inattentive. The diagnosis can be complicated because other types of childhood disorders may exhibit similar behaviors (e.g., attention deficit disorders [ADD]). Therefore, results of auditory processing tests are important to differentiate between APD and ADD. In the follo... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1671955 Sat, 01 Mar 2008 05:00:00 +0100 1671955 http://www.medworm.com/index.php?rid=1671954&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18664072%26dopt%3DAbstract We report our first experiences of transcatheter closure of perimembranous and muscular VSD. Between May 2005 and September 2006, transcatheter closure of VSD was attempted in 38 patients. Implantation was successful in 37 patients. In one patient, the procedure failed because of the long sheath kinking. We observed important complications in three patients: severe tricuspid valve regurgitation, residual VSD and tricuspid valve regurgitation and right bundle branch block in the short-term follow-up. Transcatheter device closure with Amplatzer device seems to be effective and safe in the treatment of perimembranous and muscular VSDs. Tricuspid valve incompetence may cause problems. Long-term results are required to determine the efficacy and safety. PMID: 18664072 [PubMed - in process] ... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1671954 Sat, 01 Mar 2008 05:00:00 +0100 1671954 http://www.medworm.com/index.php?rid=1671953&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18664073%26dopt%3DAbstract Authors: Celik U, Yildizdaş D, Alhan E, Celik T, Attila G, Sertdemir Y, Tepe T The role of endothelial nitric oxide synthase gene intron 4 a/b (eNOS4a/b) variable number of tandem repeats (VNTR) polymorphism in various diseases was investigated. We investigated whether this polymorphism is associated with susceptibility to sepsis and its clinical features such as acute respiratory distress syndrome (ARDS), multiorgan dysfunction syndrome (MODS) and shock. eNOS4a/b VNTR polymorphism was determined by the polymerase chain reaction in 100 children with sepsis and in 134 healthy controls. The genotype distribution of eNOS4 was not different between the patients and controls (p=0.44). There was no statistically significant association between genotypes/allele frequency and outcomes li... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1671953 Sat, 01 Mar 2008 05:00:00 +0100 1671953 http://www.medworm.com/index.php?rid=1671952&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18664074%26dopt%3DAbstract Authors: Yildirim I, Ceyhan M, Gür D, Kaymakoğlu I Bacteriological failure with penicillin that has been used widely for years in group A beta hemolytic streptococcal (GABHS) tonsillopharyngitis is being reported as high as 30%. Because of this unresponsiveness, many different agents are being used as alternative options. We evaluated the effect of clarithromycin, amoxicillin/clavulanate (CAM), cefprozil and benzathine penicillin G (Pen G) on the bacteriological cure, beta-lactamase production, pharyngeal microflora and alpha hemolytic streptococci (AHS) when used in the treatment of pediatric GABHS tonsillopharyngitis. Intramuscular Pen G and oral clarithromycin, CAM and cefprozil were administered to 70 patients who were between 2-16 years of age. Three throat swabs were o... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1671952 Sat, 01 Mar 2008 05:00:00 +0100 1671952 http://www.medworm.com/index.php?rid=1671951&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18664075%26dopt%3DAbstract In conclusion, pediatric rheumatologists should be aware of the frequency of neuropsychiatric disturbances in SLE. The neuropsychiatric disorders do not always correlate with disease activity and these children need professional psychological evaluation. PMID: 18664075 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1671951 Sat, 01 Mar 2008 05:00:00 +0100 1671951 http://www.medworm.com/index.php?rid=1671950&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18664076%26dopt%3DAbstract In conclusion, on the basis of the data gathered in this study, the cases of acute gastroenteritis seem to represent an important cause of hospitalization in the Salento peninsula. PMID: 18664076 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1671950 Sat, 01 Mar 2008 05:00:00 +0100 1671950 http://www.medworm.com/index.php?rid=1671949&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18664077%26dopt%3DAbstract We report here on 14 patients with definite diagnosis of AS who displayed the characteristic clinical features of the syndrome and additional findings not previously reported, along with the follow-up data concerning neuromotor development and seizures. PMID: 18664077 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1671949 Sat, 01 Mar 2008 05:00:00 +0100 1671949 http://www.medworm.com/index.php?rid=1671948&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18664078%26dopt%3DAbstract This report describes clinical features and tactics of treatment of atrial tachyarrhythmias in infancy. Electrophysiologic study was performed in all 20 infants (2 weeks - 12 months old) in order to determine the mechanism of arrhythmia and to predict the clinical efficacy of management. Reciprocating mechanism was revealed in 12 infants. Atrial flutter was diagnosed for 10 infants among whom only 2 patients were older than two months. Six infants were found to have flutter conduction with a rate of 1:1. Four infants had congestive heart failure, 3 of them with a structurally normal heart. Half of the infants with atrial flutter needed long-term antiarrhythmic therapy. Electrotherapy for termination of atrial flutter was effective in all of them. Automatic atrial tachycardia in eight infan... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1671948 Sat, 01 Mar 2008 05:00:00 +0100 1671948 http://www.medworm.com/index.php?rid=1671947&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18664079%26dopt%3DAbstract The objective of this study was to determine the effect of swimming on bone metabolism during adolescence. Swimming, as a non-weight-bearing sport, has been considered to be insignificant in the maintenance of bone mass. We studied whether swimming is associated with a higher peak bone mass. Forty swimmers (males aged 10-17 years and females aged 9-16 years) were studied. The control group consisted of the same number of adolescents aged between 10-16 years who did not swim; distribution of male and female gender was similar in the non-swimming control group compared to the swimming group. Adolescents were matched for age, gender and pubertal stages based on Tanner staging. All subjects underwent combined measurement of bone mineral metabolism by dual-energy X-ray absorptiometry of total b... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1671947 Sat, 01 Mar 2008 05:00:00 +0100 1671947 http://www.medworm.com/index.php?rid=1671946&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18664080%26dopt%3DAbstract In this study, we aimed to assess the quality and quantity of tears among premature and term newborns. Tear ferning and Schirmer's tests were conducted over the first 10 days of life. Correlations between tear ferning patterns, Schirmer's scores, post-conceptional age, and birth weight were evaluated. Forty-six newborns (23 preterm, 23 term) were enrolled, with a mean post-conceptional age of 36.6 weeks and a mean weight of 2598.2 g. Mean total, basal and reflex Schirmer's test results were 13.5 mm, 6.7 mm and 6.8 mm, on the right and 14.0 mm, 7.1 mm and 6.9 mm on the left eye, respectively. Median ferning score was 2 (range 1-3) bilaterally. Schirmer scores were correlated with ferning capacity and post-conceptional age. Our study shows that newborns secrete moderate quantity, good qualit... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1671946 Sat, 01 Mar 2008 05:00:00 +0100 1671946 http://www.medworm.com/index.php?rid=1671945&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18664081%26dopt%3DAbstract Authors: Hirfanoğlu T, Soysal AS, Gücüyener K, Cansu A, Serdaroğlu A The study aimed to evaluate the level of perception, attitude, and knowledge of pediatric residents to attention-deficit/hyperactivity disorder (ADHD) by a questionnaire based on the Diagnostic and Statistical Manual of Mental Disorders (4th ed) diagnostic criteria. One hundred and fifty-six pediatric residents from university and state hospitals answered a four-step Likert type questionnaire form consisting of 43 questions regarding sociodemographic features, age, duration of residency, marital status, and general knowledge of ADHD, differential diagnosis, coexisting conditions, and management of ADHD. Of the residents, 127 (81.4%) stated that their knowledge on ADHD was deficient, and 123 (85.2... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1671945 Sat, 01 Mar 2008 05:00:00 +0100 1671945 http://www.medworm.com/index.php?rid=1671944&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18664082%26dopt%3DAbstract We report the first case with Wilson's disease who presented with nodular fatty infiltration in the liver in childhood. PMID: 18664082 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1671944 Sat, 01 Mar 2008 05:00:00 +0100 1671944 http://www.medworm.com/index.php?rid=1671943&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18664083%26dopt%3DAbstract Authors: Unal S, Durmaz E, Erkoçoğlu M, Bayrakçi B, Bircan O, Alikaşifoğlu A, Cetin M Hypercalcemia is a well-recognized complication of neoplastic disorders. Herein, we report a hypercalcemic pediatric acute lymphoblastic leukemia case at presentation refractory to hydration, furosemide, pamidronate and calcitonin. Normal serum calcium levels were achieved with the initiation of chemotherapy protocol including vincristine, daunomycin and high-dose methylprednisolone. The impact of high-dose methylprednisolone in the correction of severe hypercalcemia in steroid-responsive tumors as an initial treatment approach or for cases refractory to other measures may be life-saving. PMID: 18664083 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1671943 Sat, 01 Mar 2008 05:00:00 +0100 1671943 http://www.medworm.com/index.php?rid=1671942&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18664084%26dopt%3DAbstract We report a case of trisomy 18 (47, XX+18) with intrathoracic kidney. It was discovered incidentally as an opacity at the right lower hemithorax on the chest radiograph, later confirmed by magnetic resonance imaging. Ultrasound can be used as the first-line imaging modality for intrathoracic kidney, even in the prenatal period. PMID: 18664084 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1671942 Sat, 01 Mar 2008 05:00:00 +0100 1671942 http://www.medworm.com/index.php?rid=1671941&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18664085%26dopt%3DAbstract Authors: Tutak E, Satar M, Ozbarlas N, Uğuz A, Yapicioğlu H, Narli N, Bayram I Cardiac tumors are uncommon in neonates and most of them are histologically benign. The most common cardiac tumor in neonates and infants is rhabdomyoma. Malignant cardiac tumors are considerably rarer, and rhabdomyosarcoma (RMS) is the leading malignancy. To our knowledge, only one case of intrapericardial RMS was reported in the literature, in a seven-month-old baby. Here we present another newborn baby with intrapericardial RMS. PMID: 18664085 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1671941 Sat, 01 Mar 2008 05:00:00 +0100 1671941 http://www.medworm.com/index.php?rid=1671940&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18664086%26dopt%3DAbstract This report documents a new endoscopic management modality for congenital membranous stenosis in the third portion of the duodenum. Standard approaches to duodenal stenosis in newborns include a laparotomy with an enteroenterostomy, bypassing the obstruction, or a duodenoduodenostomy with excision. We successfully developed a modification of the endoscopic treatment modality for congenital duodenal diaphragm. PMID: 18664086 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1671940 Sat, 01 Mar 2008 05:00:00 +0100 1671940 http://www.medworm.com/index.php?rid=1671939&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18664087%26dopt%3DAbstract Authors: Cetin II, Bikmaz YE, Varan B, Tokel K Rheumatic fever is still one of the major public health problems in developing countries. Recurrences have been reported during continuous regular prophylaxis. Here, we describe a 13-year-old girl who had four apparent recurrences of carditis while on a regimen of intramuscular benzathine penicillin G (BPG) every three weeks. The interesting and special features of this case were the presence of frequent recurrences of carditis with no evidence of arthritis despite regular BPG injections every three weeks, the requirement of long-term corticosteroid therapy due to these recurrences, and the shortness of time periods between attacks after withdrawal of steroid therapy. In this case, the administration of supraphysiologic doses of glucocorti... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1671939 Sat, 01 Mar 2008 05:00:00 +0100 1671939 http://www.medworm.com/index.php?rid=1671938&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18664088%26dopt%3DAbstract Authors: Yalçin S, Ciftçi AO, Simşek H, Haliloğlu M, Sahin B, Senocak ME Pancreatic lithiasis causing chronic pancreatitis is a very rare entity in childhood. A five-year-old girl presenting with pancreatic lithiasis was treated successfully with a well-organized diagnostic and therapeutic algorithm. The authors emphasize that early diagnosis followed by appropriate therapeutic pancreatographic procedures instead of primary invasive surgical approach can certainly ameliorate progressive and irreversible pancreatic damage. The clinicopathologic features of this rare entity are discussed, with emphasis on diagnosis and treatment. PMID: 18664088 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1671938 Sat, 01 Mar 2008 05:00:00 +0100 1671938 http://www.medworm.com/index.php?rid=1671937&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18664089%26dopt%3DAbstract We describe a new patient with ring chromosome 22 syndrome and discuss the common features of the previously reported cases. Our patient had the major features of this syndrome including mental retardation, hypotonia, motor delay, microcephaly, dysplastic large ears, lack of speech, and hyperactivity disorder. Magnetic resonance imaging findings also revealed an arachnoid cyst, found in the posterior cerebellum. In patients with ring chromosome 22, variable clinical manifestations may be seen due to the size of lost sequences near the telomere. By fluorescent in situ hybridization (FISH) technique, LSI DiGeorge/VCFS/ ARSA locus-specific probes are used to detect deleted sequences. We found that 22q11.2 regions were intact on both chromosomes 22, but 22q13.3 (Arylsulfatase A; ARSA region) w... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1671937 Sat, 01 Mar 2008 05:00:00 +0100 1671937 http://www.medworm.com/index.php?rid=1671936&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18664090%26dopt%3DAbstract We present a 10-year-old girl with intestinal Crohn's disease complicated with perianal skin tags and asymptomatic unilateral labial hypertrophy. The course of her lesion was independent of the intestinal disease and responded significantly to medical treatment including azathioprine and topical steroid. We emphasize that although vulval involvement in childhood is uncommon, Crohn's disease must be considered in the differential diagnosis of nontender, red, edematous lesions of the genital area. PMID: 18664090 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1671936 Sat, 01 Mar 2008 05:00:00 +0100 1671936 http://www.medworm.com/index.php?rid=1671935&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18664091%26dopt%3DAbstract We present this case for the psychological and surgical aspects of this very interesting entity. We also review the recent literature related with Proteus syndrome. PMID: 18664091 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1671935 Sat, 01 Mar 2008 05:00:00 +0100 1671935 http://www.medworm.com/index.php?rid=1671934&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18664092%26dopt%3DAbstract Authors: Erdeve O, Atasay B, Arsan S PMID: 18664092 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1671934 Sat, 01 Mar 2008 05:00:00 +0100 1671934 http://www.medworm.com/index.php?rid=1671933&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18664093%26dopt%3DAbstract Authors: Ozsoylu S PMID: 18664093 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1671933 Sat, 01 Mar 2008 05:00:00 +0100 1671933 http://www.medworm.com/index.php?rid=1332847&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18365584%26dopt%3DAbstract Authors: Yurdakök M Necrotizing enterocolitis (NEC) is a devastating disease of premature infants, with a mortality rate of 10-50%. It is uncommon in term infants and in premature infants who have not yet been fed. Most commonly NEC develops suddenly in a preterm infant who was otherwise well, with initial symptoms of abdominal distention, bilious or bloody emesis or gastric aspirates, hematochezia, and pneumatosis intestinalis, and sometimes progresses quickly to include bowel perforation, acidosis, shock, and death. Trigger factors (i.e. perinatal hypoxia, mild infection or formula feeding) cause focal mild intestinal mucosal injury. In the presence of proliferation of commensal bacteria, local breakdown of mucosal barrier may cause entry of bacterial products (e.g. lipopolysacc... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1332847 Tue, 01 Jan 2008 05:00:00 +0100 1332847 http://www.medworm.com/index.php?rid=1332846&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18365585%26dopt%3DAbstract Authors: Köroğlu TF, Atasever S, Duman M The aim of this study was to describe and assess the structure, organization, and staffing of pediatric intensive care services in Turkey. A survey was sent to major university and government hospitals. Out of the 40 hospitals stating to provide pediatric intensive care, 34 responded to the survey (85% response rate). In the majority (81.2%) of hospitals, pediatric intensive care was provided in single room units or within the pediatric ward. Unit size ranged from 1-16 beds with an average of 6.8 +/- 4.2 operational beds per unit. Much of the equipment and a sufficient number of specialists for pediatric intensive care unit (PICU) care were present in the surveyed hospitals. However, only 12 units had a pediatric intensivist on staff ... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1332846 Tue, 01 Jan 2008 05:00:00 +0100 1332846 http://www.medworm.com/index.php?rid=1332845&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18365586%26dopt%3DAbstract This study captured the baseline QOL information about the pediatric asthmatic population and factors influencing QOL and will facilitate longitudinal monitoring. PMID: 18365586 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1332845 Tue, 01 Jan 2008 05:00:00 +0100 1332845 http://www.medworm.com/index.php?rid=1332844&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18365587%26dopt%3DAbstract Authors: Ozen M, Kanra G, Kara A, Ataş A, Seçmeer G, Ceyhan M, Cengiz AB, Belgin E Controlled trials concerning adjuvant dexamethasone therapy in bacterial meningitis do not point unequivocally to a beneficial effect on hearing ability. We investigated the remote adverse outcomes of pneumococcal meningitis and, if any, beneficial effects of adjuvant dexamethasone therapy on hearing ability. Fifty-five subjects who experienced pneumococcal meningitis between 1987-97 were divided into two groups as 25 subjects who did not receive dexamethasone (Group 1) and the remaining 30 subjects who did (Group 2). All subjects underwent pure tone thresholds estimation. There were a total of 11 subjects (20%) with sensorineural hearing impairment (SNHI): 6 in the first group (24%) and 5 in ... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1332844 Tue, 01 Jan 2008 05:00:00 +0100 1332844 http://www.medworm.com/index.php?rid=1332843&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18365588%26dopt%3DAbstract Authors: Bora G, Ozkan B, Dayangaç-Erden D, Erdem-Yurter H, Coşkun T Vitamin D deficient rickets is prevalent in Turkey and a considerable number of children are at risk of growth retardation, impaired bone formation and fracture. In order to check whether vitamin D receptor (VDR) gene polymorphism relates to the vitamin D deficient rickets, we analyzed VDR gene FokI, TaqI and ApaI polymorphisms in 24 Turkish vitamin D deficient rickets patients and 100 healthy controls. We found that "A" (ApaI) allele is more abundant in patients than controls (83 vs 57%, p = 0.002) but there were no significant differences for FokI (p = 0.693) and TaqI (p = 0.804) allele frequencies between patients and controls. We also showed that the frequency of Tt and Aa genotypes was significantly de... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1332843 Tue, 01 Jan 2008 05:00:00 +0100 1332843 http://www.medworm.com/index.php?rid=1332842&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18365589%26dopt%3DAbstract Authors: Orhan D, Kalel G, Saltik-Temizel IN, Demir H, Bulun A, Karaağaoğlu E, Cağlar M Helicobacter pylori (H. pylori) is a common cause of gastritis in both children and adults, and its incidence increases every year. The aims of this study were to evaluate the histopathologic features of H. pylori gastritis and to compare immunohistochemical with histochemical [hematoxylin-eosin (HE) and Giemsa] staining of gastric biopsy specimens for the detection of H. pylori infection from urea breath test (UBT) (-) and UBT (+) children. Seventy-eight gastric biopsies from pediatric patients who were administered UBT were included in this study. Gastric biopsy specimens were evaluated histopathologically and graded according to the Sydney system. HE, Giemsa and immunohistochemi... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1332842 Tue, 01 Jan 2008 05:00:00 +0100 1332842 http://www.medworm.com/index.php?rid=1332841&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18365590%26dopt%3DAbstract Authors: Salehzadeh F, Emami D, Zolfegari AA, Yazdanbod A, Habibzadeh S, Bashardost B, Barak M, Feizi I, Azimi H, Jastan M, Khalafi J Familial Mediterranean fever (FMF), which is the prototype of the hereditary periodic fever syndromes, is common in the countries around the Mediterranean Sea. Considering its geographical position in the northwest of Iran, with its population of Turkish origin and its vicinity to the Mediterranean Sea, th incidence of FMF should be high in Ardabil. The goal of this study was to introduce FMF as a disease with significant outbreak in this area. Based on the Tel-Hashomer criteria, patients suffering from FMF were collected from private clinics together with the medical records of adult and pediatric rheumatology clinics. Of 112 total patients determined, ... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1332841 Tue, 01 Jan 2008 05:00:00 +0100 1332841 http://www.medworm.com/index.php?rid=1332840&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18365591%26dopt%3DAbstract This study clearly showed that children with CD were at an increased risk of dental enamel defects compared with healthy subjects. Enamel defects were associated with an increased caries incidence. PMID: 18365591 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1332840 Tue, 01 Jan 2008 05:00:00 +0100 1332840 http://www.medworm.com/index.php?rid=1332839&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18365592%26dopt%3DAbstract Authors: Seçmeer G, Ciftçi AO, Kanra G, Ceyhan M, Kara A, Cengiz AB, Kiper N, Haliloğlu M, Ozçelik U, Cağdaş DN Ninety-eight patients with diagnosis of community-acquired pneumonia and parapneumonic effusion were retrospectively evaluated in order to determine the demographic properties of the patients, etiologic microorganism and the resistance patterns. Ages of study groups were between 2 to 16 years (mean 6.5 +/- 3.5 years) and 56 of 98 patients (56%) were male. There were four groups: Pneumonia (Group 1, n: 57), pleural effusion-medical treatment (Group 2, n: 18), pleural effusion-tube thoracostomy (Group 3, n: 19), and pleural effusion-operative treatment (Group 4, n: 4). Pre-admission antibiotic use was up to 84% in study groups. Evaluation of sea... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1332839 Tue, 01 Jan 2008 05:00:00 +0100 1332839 http://www.medworm.com/index.php?rid=1332838&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18365593%26dopt%3DAbstract In conclusion, the sonographic feature of PHES appears to be more specific for detecting NP in childhood pneumonia. In children with pneumonia with PHES in consolidated lung, the diagnosis of NP can be suggested with confidence, and it is important to be aware of the life-threatening complication of pneumothorax to decrease morbidity. PMID: 18365593 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1332838 Tue, 01 Jan 2008 05:00:00 +0100 1332838 http://www.medworm.com/index.php?rid=1332837&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18365594%26dopt%3DAbstract In conclusion, the examination of peripheral blood lymphocyte subsets in children with frequent upper respiratory tract infections is important in evaluating cellular immune alterations due to antigenic stimulation; however, it is neither essential nor cost-effective in the management of the disease. This study has shown that both the percentage and absolute numbers of peripheral blood lymphocyte subsets maintain their normal status in children with frequent upper respiratory tract infections. PMID: 18365594 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1332837 Tue, 01 Jan 2008 05:00:00 +0100 1332837 http://www.medworm.com/index.php?rid=1332836&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18365595%26dopt%3DAbstract Authors: Tavil B, Seçmeer G, Ozen H, Cengiz AB, Unal S, Gürgey A A seven-year-old patient was admitted to our hospital with the complaints of fever, malaise, and abdominal distention. In the bone marrow aspiration smears, leishmania amastigotes were observed. The patient was diagnosed as having visceral leishmaniasis (VL) and treated with liposomal amphotericin B (L-AMB). The authors report their observation of foamy histiocytes seen in the bone marrow aspiration smears of the patient with VL after L-AMB treatment. This effect of L-AMB needs to be recognized, since L-AMB may represent a further condition in addition to the other diseases that are associated with foamy histiocytes in the bone marrow. PMID: 18365595 [PubMed - in process] (Source: The Turkish Journal of Pedi... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1332836 Tue, 01 Jan 2008 05:00:00 +0100 1332836 http://www.medworm.com/index.php?rid=1332835&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18365596%26dopt%3DAbstract Authors: Skoulakis CE, Drivas EI, Papadakis CE, Bizaki AJ, Stavroulaki P, Helidonis ES Langerhans cell histiocytosis (LCH) is a rare disease that may affect multiple organs. The etiology of LCH remains unclear to date. It is currently believed that clonal accumulation and proliferation of CD1a-positive Langerhans cells are causative. The term LCH or histiocytosis X refers to three separate illnesses (listed in order of increasing severity): eosinophilic granuloma, Hand-Schüller-Christian disease and Letterer-Siwe disease. A seven-month-old boy presented with history of recurrent bilateral otitis media and rash and seborrheic areas on his scalp. Two days prior, his mother noticed a small lump over the right mastoid. Lateral skull X-ray (Schüller) was evidence for lytic lesion ... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1332835 Tue, 01 Jan 2008 05:00:00 +0100 1332835 http://www.medworm.com/index.php?rid=1332834&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18365597%26dopt%3DAbstract In this report, we describe two cases of acute ITP complicated secondary to parvovirus B19 or Epstein-Barr virus (EBV) infections who were unresponsive to initial therapeutic measures, but who responded to long-term intravenous immunoglobulin (IVIG) treatment, given weekly for five to eight weeks. PMID: 18365597 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1332834 Tue, 01 Jan 2008 05:00:00 +0100 1332834 http://www.medworm.com/index.php?rid=1332833&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18365598%26dopt%3DAbstract A child with Behçet's disease presenting with a spectrum of inflammatory manifestations including epididymoorchitis. Turk J Pediatr. 2008 Jan-Feb;50(1):78-80 Authors: Pektaş A, Devrim I, Beşbaş N, Bilginer Y, Cengiz AB, Ozen S Behçet's disease is a systemic vasculitis affecting arterioles and venules and is characterized by recurrent oral ulcers, genital ulcers and ocular inflammation. It can involve any organ but joints, skin, central nervous system and gastrointestinal tract are the most common sites. Here we report an 11-year-old Behçet's disease patient presenting with attacks of myositis accompanied by epididymoorchitis and periodic fever attacks as well as a separate attack of thrombophlebitis. PMID: 18365598 [PubMed - in process] (Sou... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1332833 Tue, 01 Jan 2008 05:00:00 +0100 1332833 http://www.medworm.com/index.php?rid=1332832&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18365599%26dopt%3DAbstract Acute myocardial infarction and ascending aortic aneurysm in a child with Behçet's disease. Turk J Pediatr. 2008 Jan-Feb;50(1):81-5 Authors: Zhuang J, Wang S, Zhang Z, Zeng S, Shi Y, Nong S A 12-year-old boy with a history of recurrent aphthous ulcerations and cutaneous erythema nodosum suddenly experienced chest pain. Together, the symptoms and a positive skin pathergy test established a diagnosis of Behçet's disease. An acute extensive anterior myocardial infarction was based on electrocardiography and a cardiac computed tomography confirmed an ascending aortic aneurysm. Coronary angiography showed mural irregularity and a 50% constriction in the first diagonal artery. Following treatment with urokinase, corticosteroids, colchicine, and aspirin, most symptoms gradua... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1332832 Tue, 01 Jan 2008 05:00:00 +0100 1332832 http://www.medworm.com/index.php?rid=1332831&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18365600%26dopt%3DAbstract We report a rare case of Enterococcus faecalis meningitis in an 11-year-old child with non-Hodgkin lymphoma. The patient during the course of chemotherapy became neutropenic, febrile, agitated, and disoriented with clinical signs of meningeal irritation. Culture of cerebrospinal fluid yielded Enterococcus faecalis. The patient was successfully treated with ampicillin without any neurological defects. PMID: 18365600 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1332831 Tue, 01 Jan 2008 05:00:00 +0100 1332831 http://www.medworm.com/index.php?rid=1332830&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18365601%26dopt%3DAbstract Authors: Aydemir C, Aktaş E, Eldeş N, Kutsal E, Demirel F, Ege A Stenotrophomonas maltophilia is an important nosocomial pathogen in hospitalized patients, particularly those with prior broad-spectrum antibacterial therapy. The microorganism mainly infects severely ill, debilitated patients and is most frequent in immunocompromised hosts. A prominent feature of this organism is its resistance to multiple antibiotics including beta-lactam agents, carbapenems and aminoglycosides. Community-acquired infection with Stenotrophomonas maltophilia is reported rarely. This is the first report of a child patient diagnosed with septic arthritis due to Stenotrophomonas maltophilia. PMID: 18365601 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1332830 Tue, 01 Jan 2008 05:00:00 +0100 1332830 http://www.medworm.com/index.php?rid=1332829&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18365602%26dopt%3DAbstract A rare form of Guillain-Barré syndrome: pharyngeal-cervical-brachial variant. Turk J Pediatr. 2008 Jan-Feb;50(1):91-3 Authors: Hergüner MO, Tepe T, Altunbaşak S, Baytok V Guillain-Barré syndrome is clinically characterized by acute onset of generalized, symmetrical, and ascending muscle weakness and areflexia from peripheral nerve involvement. In Guillain-Barré syndrome variants, however, some patients have unusual distribution of muscle involvement. Pharyngeal-cervical-brachial variant of Guillain-Barré syndrome is characterized by oropharyngeal, neck, and upper limb muscle involvement. Although Guillain-Barré syndrome is one of several post-infectious diseases that cause limb muscle weakness, the incidence of pharyngeal-cervical-brachial va... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1332829 Tue, 01 Jan 2008 05:00:00 +0100 1332829 http://www.medworm.com/index.php?rid=1332828&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18365603%26dopt%3DAbstract We describe a case of duodenal perforation from suspected ulcer. A premature boy was born at the gestational age of 26 weeks with a birth weight of 764 g. The Apgar score at 1 min was 3 and at 5 min had decreased to 2. He was given intermittent mandatory ventilation for one month after the birth. Ninety-eight days after birth, the infant's abdomen became distended. A supine and cross-table lateral radiograph of the abdomen revealed massive pneumoperitoneum. An exploratory laparotomy was performed, which revealed two perforations in the anterior wall of the first portion of the duodenum. The operation procedure was direct closure and intra-abdominal drainage. On the postoperative first day, he had central urorrhagia from hematencephalon. The patient's growth after surgery has been normal, w... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1332828 Tue, 01 Jan 2008 05:00:00 +0100 1332828 http://www.medworm.com/index.php?rid=1332827&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18365604%26dopt%3DAbstract Authors: Soyer T, Göl IH, Eroğlu F, Cetin A Pseudoephedrine hydrochloride (PEH) is a sympathomimetic agent that is widely used in common cold disease in children. Though side effects of PEH are well known, it is preferred by many pediatricians in order to benefit from its symptomatic relief in common cold disease. A case of acute urinary retention due to PEH in a three-year-old boy is reported. The aim of this case report is to emphasize the clinical importance and differential diagnosis of PEH overdose in children and to discuss the appropriate treatment approach to PEH overdose in the emergency department. PMID: 18365604 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1332827 Tue, 01 Jan 2008 05:00:00 +0100 1332827 http://www.medworm.com/index.php?rid=1212389&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18246734%26dopt%3DAbstract Authors: Tunçbilek E, Ozgüç M Turkey is among the most populous countries of the world, and has a young population structure. The rate of consanguinity has been approximately 20-25% for the last 25 years. Various studies have shown that high consanguinity can be a contributing factor to the high incidence of some rare autosomal recessive diseases. Hemoglobinopathies are an important health problem, and Turkey also has one of the highest incidences of phenylketonuria in the world. Training and education in medical genetics, established as a specialty since 1972, play an important role in the setting of genetic services and meeting public health problems. Prenatal and preimplantation diagnosis is available for a variety of fetal diseases. PMID: 18246734 [PubMed - in pr... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1212389 Mon, 01 Oct 2007 04:00:00 +0100 1212389 http://www.medworm.com/index.php?rid=1212388&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18246735%26dopt%3DAbstract The objective in this study was to determine whether there was any relation between leptin and vascular endothelial growth factor (VEGF) in children with cyanotic and acyanotic heart anomalies. The study group consisted of 18 children with cyanotic congenital heart disease (CHD) and 20 age-adjusted children with acyanotic CHD as controls. Serum VEGF and leptin levels were determined by enzyme-linked immunosorbent assay (ELISA). The mean VEGF level was 149.25+/-42.93 pg/ml (range 80.66-217.00) in the cyanotic group and 88.18+/-20.94 pg/ml (range 48.44-112.71) in the acyanotic group (p<0.001). The mean leptin level was 7.55+/-1.46 ng/ml (range 4.08-10.25) in the cyanotic group and 6.89+/-1.43 ng/ml (range 2.67-8.57) in the acyanotic group (p=0.168). There was a significant positive correl... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1212388 Mon, 01 Oct 2007 04:00:00 +0100 1212388 http://www.medworm.com/index.php?rid=1212387&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18246736%26dopt%3DAbstract Authors: Yaramiş A, Bükte Y, Katar S, Ozbek MN This prospective study was done over seven years from 1996 to 2003 to investigate the chest computed tomography scan findings along with other radiologic examinations that included chest roentgenography and cranial computed tomography in children with tuberculous meningitis (TBM). Chest roentgenography demonstrated abnormal findings in 32 cases (43%) (hilar adenopathy, 32%; miliary pattern, 18%; bronchopneumonic infiltrate, 24%), while chest computerized tomography was abnormal in 65 cases (88%; p<0.005): mediastinal and hilar lymphadenopathy were present in 46% (p<0.005); miliary pattern, in 23% (p<0.05); and bronchopneumonic infiltrate, in 23% (p<0.05). Cranial computerized tomography was abnormal in 68 cases (92%)... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1212387 Mon, 01 Oct 2007 04:00:00 +0100 1212387 http://www.medworm.com/index.php?rid=1212386&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18246737%26dopt%3DAbstract In conclusion, S. pneumoniae carriage rates determined in healthy children were high and PNSSP strains also showed increased resistance to other antimicrobials. PMID: 18246737 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1212386 Mon, 01 Oct 2007 04:00:00 +0100 1212386 http://www.medworm.com/index.php?rid=1212385&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18246738%26dopt%3DAbstract This study supports that it is uncommon for household falls to cause injuries significant enough to require professional medical care. Even falls from a distance of greater than three feet result in only mild injury with no neurological findings. PMID: 18246738 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1212385 Mon, 01 Oct 2007 04:00:00 +0100 1212385 http://www.medworm.com/index.php?rid=1212384&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18246739%26dopt%3DAbstract This study reveals a novel missense mutation (N258S) in the KCNQ2 gene between the S5 domain and the pore of the potassium channel in two BFNC patients in a Turkish family. The absence of the mutation both in the healthy members of the family and in a control group, and the lack of any other change in the KCNQ2 gene of the patients indicate that N258S substitution is a pathogenic mutation leading to epileptic seizures in this family. PMID: 18246739 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1212384 Mon, 01 Oct 2007 04:00:00 +0100 1212384 http://www.medworm.com/index.php?rid=1212383&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18246740%26dopt%3DAbstract In conclusion, for the treatment of children with AOM, the clinical success of single-dose intramuscular ceftriaxone and of five-day azithromycin treatments was comparable to that of the traditional 10-day therapy with high-dose amoxicillin/clavulanate. PMID: 18246740 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1212383 Mon, 01 Oct 2007 04:00:00 +0100 1212383 http://www.medworm.com/index.php?rid=1212382&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18246741%26dopt%3DAbstract Authors: Taner Y, Erdoğan-Bakar E, Turanli G, Topçu M This investigation examined psychopathology and IQ levels in 30 children with CSWS and 42 children with BRE and compared them with 40 healthy controls and 23 children with absence epilepsy by using the Schedule for Affective Disorders and Schizophrenia for School-Age Children (K-SADS) and Wechsler Intelligence Test for Children (WISC-R). The CSWS and BRE groups had the highest rate of psychiatric diagnoses and lowest IQ scores. The BRE group had higher rates of psychopathology and lower IQ scores compared to the healthy controls. While BRE and absence groups did not differ with regard to presence of psychopathology, IQ levels and types of psychopathologies, children with CSWS had more psychiatric disorders and lower IQ sc... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1212382 Mon, 01 Oct 2007 04:00:00 +0100 1212382 http://www.medworm.com/index.php?rid=1212381&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18246742%26dopt%3DAbstract Authors: Soysal A, Eraşov K, Akpinar I, Bakir M Ceftriaxone, a third-generation cephalosporin, is widely used for treating infection during childhood. It is mainly eliminated in the urine, but approximately 40% of a given dose is unmetabolized and secreted into bile. The aim of this study was to investigate the frequency, clinical characteristics, and outcome of biliary sludge (BS) in addition to potential contributing risk factors in children who receive ceftriaxone. Biliary ultrasonography was performed at the time of randomization before ceftriaxone treatment was started, on the 5th and 10th days, and at the end of the treatment. If BS was detected, patients were followed-up weekly by sonographic examination until the BS or biliary lithiasis (BL) disappeared. A total of 114 ch... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1212381 Mon, 01 Oct 2007 04:00:00 +0100 1212381 http://www.medworm.com/index.php?rid=1212380&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18246743%26dopt%3DAbstract Authors: Yalçin SS, Unal S, Gümrük F, Yurdakök K Pallor is deemed useful in the evaluation of patients suspected of anemia, although its perceived presence or absence may be misleading in cases with increased pigmentation with iron, melanin, or bilirubin. The purpose of this study was to determine the validity of pallor in the detection of anemia in children with beta-thalassemia as an iron overload model. Patients with beta-thalassemia A aged 2 to 32 years who were admitted to the Hematology Unit, Department of Pediatrics, Ihsan Doğramaci Children's Hospital, Ankara, Turkey were assessed for the presence of pallor in three anatomic sites (palm, conjunctiva, buccal mucosa) by a trained pediatrician. Overall, 105 observations were done. The mean age of the pati... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1212380 Mon, 01 Oct 2007 04:00:00 +0100 1212380 http://www.medworm.com/index.php?rid=1212379&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18246744%26dopt%3DAbstract Authors: Celebi A, Yalçin Y, Erdem A, Zeybek C, Akdeniz C, Polat TB We assessed the efficacy and safety of stent implantation into the ductus arteriosus in infants with cyanotic heart disease. Ten patients with duct-dependent or diminished pulmonary circulation underwent cardiac catheterization with the aim of stent implantation. Coronary stents of 3.5-4 mm in diameter were used and successfully implanted in eight. All patients in whom stent implantation was successful had adequate relief of their cyanosis and were discharged home. During a mean follow-up of 9.3 months (median 10 months), one patient had evidence of restenosis of the stent at five months. Re-dilatation of the stenosed stent was attempted but was unsuccessful and a modified left Blalock-Taussig shunt was placed sur... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1212379 Mon, 01 Oct 2007 04:00:00 +0100 1212379 http://www.medworm.com/index.php?rid=1212378&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18246745%26dopt%3DAbstract We report three patients with congenital chylothorax and discussed the clinical course and treatment options. Cases 1 and 2 with congenital chylothorax were treated by chest tube placement and total parenteral nutrition (TPN), and were fed a formula rich in medium-chain triglyceride. They were discharged home without any sequelae. Our 3rd case with chylothorax did not respond to the conventional therapies. Octreotide infusion was tried without any benefits and necessitated surgical intervention, but the infant developed chronic lung disease requiring nasal oxygen therapy until three months of age. All three patients developed complications of chylothorax treatment like chest tube dysfunction, pneumothorax, nosocomial sepsis, and cholestasis. Management of congenital chylothorax necessitate... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1212378 Mon, 01 Oct 2007 04:00:00 +0100 1212378 http://www.medworm.com/index.php?rid=1212377&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18246746%26dopt%3DAbstract Authors: Hergüner MO, Altunbaşak S, Baytok V Subacute sclerosing panencephalitis (SSPE) usually begins insidiously and follows a subacute course with relentless but slow progression to death. In recent years, however, patients with acute or fulminant course were reported. In this article, we report on three patients (2 girls, 1 boy) with SSPE who developed an acute and fulminant course. Subacute sclerosing panencephalitis may be seen with more atypical symptoms and more acute and fulminant courses due to various undetermined reasons. Early diagnosis is very important for the effectiveness of treatment. Children presenting with acute or subacute neurologic symptoms should be examined for SSPE, especially if they have no risk factors for hereditary neurodegenerative/ neurometa... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1212377 Mon, 01 Oct 2007 04:00:00 +0100 1212377 http://www.medworm.com/index.php?rid=1212376&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18246747%26dopt%3DAbstract We present the results of a three-year long observation of a child born at the 27th week of pregnancy diagnosed with DEHSI. The boy exhibited cerebral palsy, hyperexcitability and hypoacusis. In the authors' opinion, noncystic white matter injury may not just be one of the reasons for cognitive/behavioral deficits--it may also be responsible for some cases of cerebral palsy in premature infants. PMID: 18246747 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1212376 Mon, 01 Oct 2007 04:00:00 +0100 1212376 http://www.medworm.com/index.php?rid=1212375&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18246748%26dopt%3DAbstract In conclusion, Kawasaki disease caregivers must be aware of possible sensorineural hearing loss, which is reversible by early intervention and thus improves quality of life. PMID: 18246748 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1212375 Mon, 01 Oct 2007 04:00:00 +0100 1212375 http://www.medworm.com/index.php?rid=1212374&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18246749%26dopt%3DAbstract Authors: Yilmaz A, Hazar V, Akçam M, Inanç-Gürer E, Ceken K, Artan R Post-transplant lymphoproliferative disorder (PTLD) represents a spectrum of Epstein-Barr virus (EBV)-related clinical diseases, from a benign mononucleosis-like illness to a fulminant non-Hodgkin's lymphoma. Because a large proportion of children are seronegative at the time of transplantation, recipients are at high risk of contracting primary EBV infection and subsequently developing PTLD. Surveillance techniques with antibody titers and/or polymerase chain reaction (PCR) may have a role in some high-risk settings. A 12-year-old boy whose serologic response to EBV was negative during follow-up after liver transplantation (LTx) developed Burkitt's lymphoma, a rare and the most severe variant of EBV-re... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1212374 Mon, 01 Oct 2007 04:00:00 +0100 1212374 http://www.medworm.com/index.php?rid=1212373&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18246750%26dopt%3DAbstract Authors: Imataka G, Miyamoto K, Fujiyama Y, Mitsui M, Yoshida A, Yamanouchi H, Arisaka O A male infant aged nine months with meningeal irritation and +3.5SD expansion of the circumference of the head was admitted. Brain computed tomography (CT) detected right chronic subdural hematoma and contralateral subdural hygroma. Since the cell count was increased on a cerebrospinal fluid test, acute purulent meningitis was diagnosed. A rapid latex test and culture of cerebrospinal fluid identified Streptococcus pneumoniae (PSSP) as the pathogen. Panipenem/betamiprom (PAPM/BP) was administered at 100 mg/kg/3 times for 14 days and dexamethasone was administered at 0.6 mg/kg/4 times for 4 days, and the patient recovered without sequelae. Acute purulent meningitis complicated by chronic subdural he... The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1212373 Mon, 01 Oct 2007 04:00:00 +0100 1212373 http://www.medworm.com/index.php?rid=1212372&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18246751%26dopt%3DAbstract We describe here a case of early linear focal elastosis arising in a 14-year-old Turkish boy. PMID: 18246751 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1212372 Mon, 01 Oct 2007 04:00:00 +0100 1212372 http://www.medworm.com/index.php?rid=1212371&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18246752%26dopt%3DAbstract We present a 14-year-old boy with ARS in whom the diagnosis was confirmed by ophthalmologic examination and developmental defects of the teeth and facial bones. Echocardiography revealed TA. With this case demonstrating the association between ARS and TA, the range of reported cardiac malformations is enlarged and the importance of cardiologic evaluation is emphasized in patients with ARS. PMID: 18246752 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1212371 Mon, 01 Oct 2007 04:00:00 +0100 1212371 http://www.medworm.com/index.php?rid=1212370&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18246753%26dopt%3DAbstract We report a five-month-old boy who was referred to the hospital with a presumptive diagnosis of hydrocele of the cord. Ultrasonography revealed a cystic mass within the left testis. A complete removal of the cystic mass was done. Histopathological diagnosis was simple cyst of the testis. This rare lesion should be considered in the differential diagnosis of cystic testicular lesions in infancy. The treatment of choice is simple enucleation of the cyst with sparing of the testis and related structures. PMID: 18246753 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1212370 Mon, 01 Oct 2007 04:00:00 +0100 1212370 http://www.medworm.com/index.php?rid=1212369&cid=s_36152_33_f&fid=36152&url=http%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fentrez%2Fquery.fcgi%3Ftmpl%3DNoSidebarfile%26db%3DPubMed%26cmd%3DRetrieve%26list_uids%3D18246754%26dopt%3DAbstract Authors: Wong KS, Huang YH, Wu CT A one-month-old male infant was referred because of noisy breathing sounds, feeding difficulty and shortness of breath. A lateral radiography of the neck showed abnormal soft tissue mass at tongue base. While waiting for a scheduled bronchoscopic examination, respiratory distress and noisy breathing sounds disappeared after nasogastric suctioning. Dramatic improvement in respiratory distress in a young infant with feeding difficulties may have been due to rupture of a tongue-base cyst following oropharyngeal manipulations. PMID: 18246754 [PubMed - in process] (Source: The Turkish Journal of Pediatrics) The Turkish Journal of Pediatrics journals http://www.medworm.com/rss/comments.php?id=1212369 Mon, 01 Oct 2007 04:00:00 +0100 1212369