Value in Health via MedWorm.com MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'Value in Health' source. Sat, 29 Jan 2011 20:42:59 +0100 The Role of Observational Investigations in Comparative Effectiveness Research http://www.medworm.com/index.php?rid=4240547&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00786.x Conclusions:  The CER paradigm recognizes the limitations of hierarchical models of evidence and favors application of a strength‐of‐evidence model. In this model, observational research fills gaps in randomized clinical trial data and is particularly valuable to investigate effectiveness, harms, prognosis, and infrequent outcomes as well as in circumstances where randomization is not possible and in studies of many surgical populations. Observational investigations must be designed with careful consideration of potential sources of bias and must incorporate strategies to control such bias prospectively, and their results must be reported in a uniform and transparent fashion. When these conditions can be achieved, observational research represents a valuable and critical component of... Value in Health journals http://www.medworm.com/rss/comments.php?id=4240547 Wed, 01 Dec 2010 00:00:00 +0100 4240547 Cost‐Effectiveness of Maraviroc for Antiretroviral Treatment‐Experienced HIV‐infected Individuals in Mexico http://www.medworm.com/index.php?rid=4195000&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00798.x Conclusion:  In treatment‐experienced individuals with HIV/AIDS in Mexico, maraviroc may be cost‐effective, particularly in individuals with limited options for active antiretroviral therapy (ART). (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=4195000 Mon, 22 Nov 2010 00:00:00 +0100 4195000 Cost‐Effectiveness of Specialized Multidisciplinary Heart Failure Clinics in Ontario, Canada http://www.medworm.com/index.php?rid=4194999&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00797.x Conclusions:  HF clinics appear to be a cost effective way of delivering ambulatory care to HF patients. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=4194999 Mon, 01 Nov 2010 00:00:00 +0100 4194999 Expanded HIV Screening in the United States: What Will It Cost Government Discretionary and Entitlement Programs? A Budget Impact Analysis http://www.medworm.com/index.php?rid=4071393&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00763.x ABSTRACT (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=4071393 Sat, 16 Oct 2010 13:49:55 +0100 4071393 ISPOR 4th Asia‐Pacific Conference Author Index http://www.medworm.com/index.php?rid=4058825&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00796.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=4058825 Tue, 12 Oct 2010 22:43:45 +0100 4058825 Ispor 4th asia‐pacific conference disclosure information http://www.medworm.com/index.php?rid=4058824&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00794.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=4058824 Tue, 12 Oct 2010 22:43:45 +0100 4058824 Research poster abstracts http://www.medworm.com/index.php?rid=4058823&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00793_3.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=4058823 Tue, 12 Oct 2010 22:43:45 +0100 4058823 Research podium abstracts http://www.medworm.com/index.php?rid=4058822&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00793_2.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=4058822 Tue, 12 Oct 2010 22:43:44 +0100 4058822 Cost‐Effectiveness Studies http://www.medworm.com/index.php?rid=4058821&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00793_1.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=4058821 Tue, 12 Oct 2010 22:43:44 +0100 4058821 ISPOR 13th Annual European Congress Author Index http://www.medworm.com/index.php?rid=4058820&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00795.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=4058820 Tue, 12 Oct 2010 22:43:44 +0100 4058820 Ispor 13th annual european congress disclosure information http://www.medworm.com/index.php?rid=4058819&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00792.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=4058819 Tue, 12 Oct 2010 22:43:43 +0100 4058819 Research poster abstracts http://www.medworm.com/index.php?rid=4058818&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00791_2.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=4058818 Tue, 12 Oct 2010 22:43:43 +0100 4058818 Research podium abstracts http://www.medworm.com/index.php?rid=4058817&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00791_1.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=4058817 Tue, 12 Oct 2010 22:43:42 +0100 4058817 Dimensionality and Summary Measures of the SF‐36 v1.6: Comparison of Scale‐ and Item‐Based Approach across ECRHS II Adults Population http://www.medworm.com/index.php?rid=4058816&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00703.x ABSTRACT (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=4058816 Tue, 12 Oct 2010 22:43:34 +0100 4058816 Recent Trends and Geographic Patterns of the Burden of Disease Attributable to Smoking http://www.medworm.com/index.php?rid=4058815&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00760.x ABSTRACT (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=4058815 Tue, 12 Oct 2010 22:43:34 +0100 4058815 Economic Evaluations Alongside Effectiveness Trials http://www.medworm.com/index.php?rid=4058814&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00785.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=4058814 Tue, 12 Oct 2010 22:43:33 +0100 4058814 Estimating the Effect of Medication Adherence on Health Outcomes among Patients with Type 2 Diabetes—An Application of Marginal Structural Models http://www.medworm.com/index.php?rid=4058813&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00787.x ABSTRACT (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=4058813 Tue, 12 Oct 2010 22:43:33 +0100 4058813 Methods for the Collection of Resource Use Data within Clinical Trials: A Systematic Review of Studies Funded by the UK Health Technology Assessment Program http://www.medworm.com/index.php?rid=4058812&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00788.x ABSTRACT (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=4058812 Tue, 12 Oct 2010 22:43:32 +0100 4058812 Reviewer Acknowledgment http://www.medworm.com/index.php?rid=4058811&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00790.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=4058811 Tue, 12 Oct 2010 22:43:32 +0100 4058811 How Is Evidence on Test Performance Synthesized for Economic Decision Models of Diagnostic Tests? A Systematic Appraisal of Health Technology Assessments in the UK Since 1997 http://www.medworm.com/index.php?rid=4024849&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00762.x ABSTRACT (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=4024849 Tue, 31 Aug 2010 23:00:00 +0100 4024849 Quantification of the Potential Impact of Cost‐effectiveness Thresholds on Dutch Drug Expenditures Using Retrospective Analysis http://www.medworm.com/index.php?rid=3931706&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00736.x ABSTRACT (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3931706 Tue, 31 Aug 2010 23:00:00 +0100 3931706 Persistence Patterns with Oral Antidiabetes Drug Treatment in Newly Treated Patients—A Population‐Based Study http://www.medworm.com/index.php?rid=3931705&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00761.x ABSTRACT (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3931705 Tue, 31 Aug 2010 23:00:00 +0100 3931705 Adherence, Discontinuation, and Switching of Biologic Therapies in Medicaid Enrollees with Rheumatoid Arthritis http://www.medworm.com/index.php?rid=3931704&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00764.x ABSTRACT (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3931704 Tue, 31 Aug 2010 23:00:00 +0100 3931704 Medical Services Utilization and Expenditure of Obesity‐Related Disorders in Taiwanese Adults http://www.medworm.com/index.php?rid=3931703&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00776.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3931703 Tue, 31 Aug 2010 23:00:00 +0100 3931703 The Modeled Lifetime Cost‐Effectiveness of Published Adherence‐Improving Interventions for Antihypertensive and Lipid‐Lowering Medications http://www.medworm.com/index.php?rid=3931702&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00774.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3931702 Tue, 31 Aug 2010 23:00:00 +0100 3931702 Discrete Event Simulation: The Preferred Technique for Health Economic Evaluations? http://www.medworm.com/index.php?rid=3931701&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00775.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3931701 Tue, 31 Aug 2010 23:00:00 +0100 3931701 Historical Lifetimes of Drugs in England: Application to Value of Information and Cost‐Effectiveness Analyses http://www.medworm.com/index.php?rid=3931700&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00778.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3931700 Tue, 31 Aug 2010 23:00:00 +0100 3931700 Mixed Treatment Comparison Meta‐Analysis Evaluating the Relative Efficacy of Nucleos(t)ides for Treatment of Nucleos(t)ide‐Naive Patients with Chronic Hepatitis B http://www.medworm.com/index.php?rid=3931699&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00777.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3931699 Tue, 31 Aug 2010 23:00:00 +0100 3931699 Is Longer Waiting Time for Total Knee Replacement Associated with Health Outcomes and Medication Costs? Randomized Clinical Trial http://www.medworm.com/index.php?rid=3931698&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00779.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3931698 Tue, 31 Aug 2010 23:00:00 +0100 3931698 Predicting Time Trade‐Off Health State Valuations of Adolescents in Four Pacific Countries Using the Assessment of Quality‐of‐Life (AQoL‐6D) Instrument http://www.medworm.com/index.php?rid=3931697&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00780.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3931697 Tue, 31 Aug 2010 23:00:00 +0100 3931697 Willingness to Pay for a Quality‐Adjusted Life‐Year: The Individual Perspective http://www.medworm.com/index.php?rid=3931696&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00781.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3931696 Tue, 31 Aug 2010 23:00:00 +0100 3931696 Cost–Utility Analysis of Tenofovir Disoproxil Fumarate in the Treatment of Chronic Hepatitis B http://www.medworm.com/index.php?rid=3931695&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00782.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3931695 Tue, 31 Aug 2010 23:00:00 +0100 3931695 Discrete Choice Modeling for the Quantification of Health States: The Case of the EQ‐5D http://www.medworm.com/index.php?rid=3931694&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00783.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3931694 Tue, 31 Aug 2010 23:00:00 +0100 3931694 Network Meta‐Analysis with Competing Risk Outcomes http://www.medworm.com/index.php?rid=3931693&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00784.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3931693 Tue, 31 Aug 2010 23:00:00 +0100 3931693 Health Technology Assessment and Economic Evaluation: Arguments for a National Approach http://www.medworm.com/index.php?rid=3819821&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00765.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3819821 Wed, 04 Aug 2010 23:00:00 +0100 3819821 Health Technology Assessment and Economic Evaluation across Jurisdictions http://www.medworm.com/index.php?rid=3819823&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00756.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3819823 Tue, 03 Aug 2010 23:00:00 +0100 3819823 A Multimarker Approach for the Prediction of Coronary Artery Disease: Cost‐Effectiveness Analysis http://www.medworm.com/index.php?rid=3839854&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00769.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839854 Sat, 31 Jul 2010 23:00:00 +0100 3839854 Development of the EXAcerbations of Chronic Obstructive Pulmonary Disease Tool (EXACT): A Patient‐Reported Outcome (PRO) Measure http://www.medworm.com/index.php?rid=3839853&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00772.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839853 Sat, 31 Jul 2010 23:00:00 +0100 3839853 International Development of the Patient‐Reported Outcome Indices for Multiple Sclerosis (PRIMUS) http://www.medworm.com/index.php?rid=3839852&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00767.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839852 Sat, 31 Jul 2010 23:00:00 +0100 3839852 Use of a Disease‐Specific Instrument in Economic Evaluations: Mapping WOMAC onto the EQ‐5D Utility Index http://www.medworm.com/index.php?rid=3839851&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00770.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839851 Sat, 31 Jul 2010 23:00:00 +0100 3839851 What Do International Pharmacoeconomic Guidelines Say about Economic Data Transferability? http://www.medworm.com/index.php?rid=3785571&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00771.x Conclusions: A growing number of jurisdictions are using guidelines for the economic evaluation of pharmaceuticals. The recommendations in existing guidelines regarding the transferability of clinical and economic data are quite diverse. There is a case for standardization in dealing with transferability issues. One important step would be to update guidelines more frequently. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3785571 Sat, 24 Jul 2010 23:00:00 +0100 3785571 Data Generalizability, Data Transferability, and the Political Economy of Pharmacoeconomic Guidelines http://www.medworm.com/index.php?rid=3785578&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00766.x Conclusion: The recommendations on good research practices for dealing with aspects of transferability are filling an important gap. However, in order for the applied science of Pharmacoeconomics and Outcomes Research to make up for its epistemological aim and the aim of providing normative judgments, the methodological foundation of normative judgments has to be given the same importance as the methodological foundation the scientific community is seeking to establish as good research practices. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3785578 Thu, 22 Jul 2010 23:00:00 +0100 3785578 Development of the EXAcerbations of Chronic Obstructive Pulmonary Disease Tool (EXACT): A Patient-Reported Outcome (PRO) Measure http://www.medworm.com/index.php?rid=3785577&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00772.x Conclusions: Qualitative data from patients and input from experts formed the basis of the EXACT's structure and item pool, ready for empirically based item reduction and reliability and validity testing. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3785577 Thu, 22 Jul 2010 23:00:00 +0100 3785577 The Value of Correcting Values: Influence and Importance of Correcting TTO Scores for Time Preference http://www.medworm.com/index.php?rid=3785576&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00773.x Conclusions: Correcting TTO scores has a moderate, yet nonnegligible influence on outcomes. We conclude that correcting TTO scores for time preference is feasible and influential, so that there can be a substantial value of correcting values for time preference. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3785576 Thu, 22 Jul 2010 23:00:00 +0100 3785576 International Development of the Patient-Reported Outcome Indices for Multiple Sclerosis (PRIMUS) http://www.medworm.com/index.php?rid=3785575&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00767.x Conclusions: The PRIMUS was successfully adapted into eight new languages. Most of the tests showed the PRIMUS to have good unidimensionality and to have good internal consistency, reproducibility, and construct validity. The measure is now available for use in clinical studies and trials involving these countries and the UK. Further work is required to assess the measure's responsiveness. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3785575 Thu, 22 Jul 2010 23:00:00 +0100 3785575 Functional Impairment and Disability across Mood States in Bipolar Disorder http://www.medworm.com/index.php?rid=3785574&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00768.x Conclusions: This study indicates that depressive symptoms are associated with greater negative impact on psychosocial functioning than (hypo) manic symptoms. Further deficits in functioning seem to persist during remission. The results highlight the importance of aggressively treating depression and mania and the need to develop psychosocial interventions targeting to improve functional outcomes. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3785574 Thu, 22 Jul 2010 23:00:00 +0100 3785574 A Multimarker Approach for the Prediction of Coronary Artery Disease: Cost-Effectiveness Analysis http://www.medworm.com/index.php?rid=3785573&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00769.x Conclusion: Our results support the feasibility of a multimarker approach for CAD screening. The introduction of oxidative stress/antioxidative defense markers in the clinical laboratory would be convenient and cost-effective. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3785573 Thu, 22 Jul 2010 23:00:00 +0100 3785573 Use of a Disease-Specific Instrument in Economic Evaluations: Mapping WOMAC onto the EQ-5D Utility Index http://www.medworm.com/index.php?rid=3785572&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00770.x Conclusions: EQ-5D scores can be predicted using WOMAC domain scores with an acceptable precision at both individual and group levels in patients with mild to moderate knee OA. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3785572 Thu, 22 Jul 2010 23:00:00 +0100 3785572 A Cost‐Utility Analysis of Microwave Endometrial Ablation versus Thermal Balloon Endometrial Ablation http://www.medworm.com/index.php?rid=3864198&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00704.x ABSTRACT (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3864198 Wed, 30 Jun 2010 23:00:00 +0100 3864198 The Transferability of Valuing Lost Productivity across Jurisdictions. Differences between National Pharmacoeconomic Guidelines http://www.medworm.com/index.php?rid=3864197&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00699.x ABSTRACT (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3864197 Wed, 30 Jun 2010 23:00:00 +0100 3864197 A Valuation of Infusion Therapy to Preserve Islet Function in Type 1 Diabetes http://www.medworm.com/index.php?rid=3860795&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00705.x ABSTRACT (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3860795 Wed, 30 Jun 2010 23:00:00 +0100 3860795 How Do Cost‐Effectiveness Analyses Inform Reimbursement Decisions for Oncology Medicines in Canada? The Example of Sunitinib for First‐Line Treatment of Metastatic Renal Cell Carcinoma http://www.medworm.com/index.php?rid=3839871&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00738.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839871 Wed, 30 Jun 2010 23:00:00 +0100 3839871 The Cost‐Effectiveness of Spinal Cord Stimulation for Complex Regional Pain Syndrome http://www.medworm.com/index.php?rid=3839870&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00744.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839870 Wed, 30 Jun 2010 23:00:00 +0100 3839870 Evaluating Willingness‐to‐Pay Thresholds for Dementia Caregiving Interventions: Application to the Tailored Activity Program http://www.medworm.com/index.php?rid=3839869&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00739.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839869 Wed, 30 Jun 2010 23:00:00 +0100 3839869 Projected Cost‐Effectiveness of Ezetimibe/Simvastatin Compared with Doubling the Statin Dose in the United Kingdom: Findings from the INFORCE Study http://www.medworm.com/index.php?rid=3839868&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00742.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839868 Wed, 30 Jun 2010 23:00:00 +0100 3839868 Cost‐Effectiveness of the Addition of Rituximab to CHOP Chemotherapy in First‐Line Treatment for Diffuse Large B‐Cell Lymphoma in a Population‐Based Observational Cohort in British Columbia, Canada http://www.medworm.com/index.php?rid=3839867&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00737.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839867 Wed, 30 Jun 2010 23:00:00 +0100 3839867 Measuring Patient Anxiety in Primary Care: Rasch Analysis of the 6‐item Spielberger State Anxiety Scale http://www.medworm.com/index.php?rid=3839866&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00758.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839866 Wed, 30 Jun 2010 23:00:00 +0100 3839866 An Ounce of Prevention Is Worth a Pound of Cure: A Cost‐Effectiveness Analysis of Incidentally Detected Aneurysms in Functional MRI Research http://www.medworm.com/index.php?rid=3839865&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00755.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839865 Wed, 30 Jun 2010 23:00:00 +0100 3839865 Modeling the Long‐Term Cost‐Effectiveness of the Caries Management System in an Australian Population http://www.medworm.com/index.php?rid=3839864&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00759.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839864 Wed, 30 Jun 2010 23:00:00 +0100 3839864 Modeling the Long-Term Cost-Effectiveness of the Caries Management System in an Australian Population http://www.medworm.com/index.php?rid=3675285&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00759.x Conclusion: The analysis suggests that the Caries Management System is most cost-effective in patients with a high risk of dental caries. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3675285 Fri, 18 Jun 2010 23:00:00 +0100 3675285 An Ounce of Prevention Is Worth a Pound of Cure: A Cost-Effectiveness Analysis of Incidentally Detected Aneurysms in Functional MRI Research http://www.medworm.com/index.php?rid=3675288&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00755.x Purpose: Despite ongoing debate about best practices for managing incidentally detected findings in brain research studies using magnetic resonance imaging (MRI), this issue has not been investigated from a health economics viewpoint. We applied a decision-analytic approach to assess the benefit of various strategies for functional MRI (fMRI) studies using intracranial aneurysms (IA) as a model.Methods: A decision tree and Markov model were created to simulate the impact on the lifetime costs and quality-adjusted life-years (QALY) of four different strategies for review of scans for the presence of IA. To populate the decision model, we used current evidence from the literature and results from a survey of experts.Results: Review of the anatomical scans by a nonspecialist is not cost-effec... Value in Health journals http://www.medworm.com/rss/comments.php?id=3675288 Wed, 16 Jun 2010 23:00:00 +0100 3675288 Clustering Rasch Results: A Novel Method for Developing Rheumatoid Arthritis States for Use in Valuation Studies http://www.medworm.com/index.php?rid=3675287&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00757.x Conclusions: The combined use of Rasch and k-means cluster analysis has proved to be an effective technique for identifying the most important items and levels for the construction of health states. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3675287 Wed, 16 Jun 2010 23:00:00 +0100 3675287 Measuring Patient Anxiety in Primary Care: Rasch Analysis of the 6-item Spielberger State Anxiety Scale http://www.medworm.com/index.php?rid=3675286&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00758.x Conclusion: The 6-item Spielberger State Anxiety Scale is shorter than the original version and has good psychometric properties. This would suggest the scale is a valid alternative to the full version for use in primary health-care practice and research. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3675286 Wed, 16 Jun 2010 23:00:00 +0100 3675286 The Cost-Effectiveness of Spinal Cord Stimulation for Complex Regional Pain Syndrome http://www.medworm.com/index.php?rid=3639724&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00744.x Conclusions: In selected patients with CRPS, SCS is cost-effective as an adjunct to CMM. Despite their initial increased expense, rechargeable IPGs should be considered when IPG longevity is likely to be short. These findings support policymakers to extend the use of SCS as a good value for money treatment for CRPS. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3639724 Mon, 07 Jun 2010 23:00:00 +0100 3639724 Editorial http://www.medworm.com/index.php?rid=3639732&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00735.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3639732 Sun, 06 Jun 2010 23:00:00 +0100 3639732 Cost-Effectiveness of the Addition of Rituximab to CHOP Chemotherapy in First-Line Treatment for Diffuse Large B-Cell Lymphoma in a Population-Based Observational Cohort in British Columbia, Canada http://www.medworm.com/index.php?rid=3639731&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00737.x The objective in this study was to evaluate the cost-effectiveness of CHOP-R relative to CHOP in first-line treatment of DLBCL in a population-based setting in British Columbia, Canada.Methods: We created a patient-level simulation model describing potential pathways for DLBCL patients initiating treatment with either CHOP or CHOP-R. Model parameters were populated with statistical analyses of individual-level treatment and effectiveness data and published cost estimates. All results were stratified by age at treatment initiation ( (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3639731 Sun, 06 Jun 2010 23:00:00 +0100 3639731 How Do Cost-Effectiveness Analyses Inform Reimbursement Decisions for Oncology Medicines in Canada? The Example of Sunitinib for First-Line Treatment of Metastatic Renal Cell Carcinoma http://www.medworm.com/index.php?rid=3639730&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00738.x Conclusion: This demonstrates that the cost-effectiveness ratio is only one of many factors that affect an access decision in oncology. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3639730 Sun, 06 Jun 2010 23:00:00 +0100 3639730 Evaluating Willingness-to-Pay Thresholds for Dementia Caregiving Interventions: Application to the Tailored Activity Program http://www.medworm.com/index.php?rid=3639729&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00739.x Conclusions: When WTP data are not collected prospectively or conventional metrics cannot be applied, retrospectively assessing literature-derived WTP may be acceptable for informing decision-makers of potential cost-effectiveness of a proven program. Application of WTP to TAP shows potential cost-effectiveness that can be expected under the tested WTP scenarios. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3639729 Sun, 06 Jun 2010 23:00:00 +0100 3639729 The Unit Costs of Inpatient Hospital Days, Outpatient Visits, and Daycare Treatments in the Fields of Oncology and Hematology http://www.medworm.com/index.php?rid=3639728&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00740.x Conclusions: The present study provided unit costs for inpatient hospital days, outpatient visits, and daycare treatments in the fields of oncology and hematology. The results may be used as Dutch reference unit prices in economic evaluations assessing oncological and hematological diseases. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3639728 Sun, 06 Jun 2010 23:00:00 +0100 3639728 A Competing Risks Prescription Refill Model of Compliance and Persistence http://www.medworm.com/index.php?rid=3639727&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00741.x Conclusions: The proposed competing risks model differentiates between noncompliant and nonpersistent behaviors using prescription refill data. Results from the model provide insights into the dynamics of noncompliant and nonpersistent behaviors that have not been possible with current prescription refill methodologies. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3639727 Sun, 06 Jun 2010 23:00:00 +0100 3639727 Willingness to Pay for Lung Cancer Treatment http://www.medworm.com/index.php?rid=3639726&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00743.x Conclusions: Patients would like to pay less than the actual price of the new medication for their lung cancer. Thus government and health policymakers should consider the ability to pay when making their decision regarding the coverage of new drugs. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3639726 Sun, 06 Jun 2010 23:00:00 +0100 3639726 Projected Cost-Effectiveness of Ezetimibe/Simvastatin Compared with Doubling the Statin Dose in the United Kingdom: Findings from the INFORCE Study http://www.medworm.com/index.php?rid=3639725&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00742.x Conclusions: Switching to Eze/Simva 10/40 mg is projected to be a cost-effective treatment (vs. double-statin) in UK patients with ACS. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3639725 Sun, 06 Jun 2010 23:00:00 +0100 3639725 Response to: A Methodology for Successfully Producing Global Translations of Patient‐Reported Outcomes Measures for Use in Multiple Countries by Two et al. http://www.medworm.com/index.php?rid=3839896&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00719.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839896 Mon, 31 May 2010 23:00:00 +0100 3839896 Application of the Disease‐Specific Quality of Life Assessment of Growth Hormone Deficiency in Adults (QoL‐AGHDA) Questionnaire in a General Population: Results from a French Panel Study http://www.medworm.com/index.php?rid=3839895&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2009.00689.x ABSTRACT (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839895 Mon, 31 May 2010 23:00:00 +0100 3839895 Dimensionality and Summary Measures of the SF‐36 v1.6: Comparison of Scale‐ and Item‐Based Approach Across ECRHS II Adults Population http://www.medworm.com/index.php?rid=3839894&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2009.00684.x ABSTRACT (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839894 Mon, 31 May 2010 23:00:00 +0100 3839894 International Development of the Unidimensional Fatigue Impact Scale (U‐FIS) http://www.medworm.com/index.php?rid=3839893&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00706.x ABSTRACT (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839893 Mon, 31 May 2010 23:00:00 +0100 3839893 Patient Expectations and Health‐Related Quality of Life Outcomes Following Total Joint Replacement http://www.medworm.com/index.php?rid=3839892&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2009.00685.x ABSTRACT (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839892 Mon, 31 May 2010 23:00:00 +0100 3839892 The Suitability of Polycystic Ovary Syndrome‐Specific Questionnaires for Measuring the Impact of PCOS on Quality of Life in Clinical Trials http://www.medworm.com/index.php?rid=3839891&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00696.x ABSTRACT (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839891 Mon, 31 May 2010 23:00:00 +0100 3839891 Effects of Method of Translation of Patient‐Reported Health Outcome Questionnaires: A Randomized Study of the Translation of the Rheumatoid Arthritis Quality of Life (RAQoL) Instrument for Sweden http://www.medworm.com/index.php?rid=3839890&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2009.00677.x ABSTRACT (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839890 Mon, 31 May 2010 23:00:00 +0100 3839890 Quantifying Women's Stated Benefit–Risk Trade‐Off Preferences for IBS Treatment Outcomes http://www.medworm.com/index.php?rid=3839889&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00694.x ABSTRACT (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839889 Mon, 31 May 2010 23:00:00 +0100 3839889 Using the Incremental Net Benefit Framework for Quantitative Benefit–Risk Analysis in Regulatory Decision‐Making—A Case Study of Alosetron in Irritable Bowel Syndrome http://www.medworm.com/index.php?rid=3839888&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2009.00595.x ABSTRACT (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839888 Mon, 31 May 2010 23:00:00 +0100 3839888 Impact of Waist Circumference Difference on Health‐Care Cost among Overweight and Obese Subjects: The PROCEED Cohort http://www.medworm.com/index.php?rid=3839887&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2009.00690.x ABSTRACT (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839887 Mon, 31 May 2010 23:00:00 +0100 3839887 Cost–Effectiveness of Osteoporosis Screening Followed by Treatment: The Impact of Medication Adherence http://www.medworm.com/index.php?rid=3839886&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2009.00687.x ABSTRACT (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839886 Mon, 31 May 2010 23:00:00 +0100 3839886 The Effect Size in Uncertainty Analysis http://www.medworm.com/index.php?rid=3839885&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2009.00686.x ABSTRACT (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839885 Mon, 31 May 2010 23:00:00 +0100 3839885 Economic Implications of 21‐Gene Breast Cancer Risk Assay from the Perspective of an Israeli‐Managed Health‐Care Organization http://www.medworm.com/index.php?rid=3839884&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00724.x ABSTRACT (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839884 Mon, 31 May 2010 23:00:00 +0100 3839884 Transferability of Model‐Based Economic Evaluations: The Case of Trastuzumab for the Adjuvant Treatment of HER2‐Positive Early Breast Cancer in the Netherlands http://www.medworm.com/index.php?rid=3839883&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2009.00683.x ABSTRACT (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839883 Mon, 31 May 2010 23:00:00 +0100 3839883 Modeling Complex Treatment Strategies: Construction and Validation of a Discrete Event Simulation Model for Glaucoma http://www.medworm.com/index.php?rid=3839882&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2009.00678.x ABSTRACT (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839882 Mon, 31 May 2010 23:00:00 +0100 3839882 An Evaluation of the Cost‐Effectiveness of Rituximab in Combination with Chemotherapy for the First‐Line Treatment of Follicular Non‐Hodgkin's Lymphoma in the UK http://www.medworm.com/index.php?rid=3839881&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2009.00676.x ABSTRACT (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839881 Mon, 31 May 2010 23:00:00 +0100 3839881 Factors Influencing Cost‐Related Nonadherence to Medication in Older Adults: A Conceptually Based Approach http://www.medworm.com/index.php?rid=3839880&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2009.00679.x ABSTRACT (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839880 Mon, 31 May 2010 23:00:00 +0100 3839880 A Review of Quantitative Risk–Benefit Methodologies for Assessing Drug Safety and Efficacy—Report of the ISPOR Risk–Benefit Management Working Group http://www.medworm.com/index.php?rid=3839863&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00725.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839863 Fri, 30 Apr 2010 23:00:00 +0100 3839863 Cost‐Effectiveness of Therapeutic Hypothermia to Treat Neonatal Encephalopathy http://www.medworm.com/index.php?rid=3839862&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00731.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839862 Fri, 30 Apr 2010 23:00:00 +0100 3839862 Cost‐Effectiveness of Duloxetine: The Stress Urinary Incontinence Treatment (SUIT) Study http://www.medworm.com/index.php?rid=3839861&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00729.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839861 Fri, 30 Apr 2010 23:00:00 +0100 3839861 Early‐Stage Valuation of Medical Devices: The Role of Developmental Uncertainty http://www.medworm.com/index.php?rid=3839860&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00726.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839860 Fri, 30 Apr 2010 23:00:00 +0100 3839860 Differences in Child versus Parent Reports of the Child's Health‐Related Quality of Life in Children with Epilepsy and Healthy Siblings http://www.medworm.com/index.php?rid=3839859&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00732.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839859 Fri, 30 Apr 2010 23:00:00 +0100 3839859 Small Budget Impact Is a Result of Flawed Assumptions and Ignores Questionable Cost‐Effectiveness for RSV Prophylaxis http://www.medworm.com/index.php?rid=3839858&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00723.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839858 Fri, 30 Apr 2010 23:00:00 +0100 3839858 General Population Reference Values for the French Version of the EuroQol EQ‐5D Health Utility Instrument http://www.medworm.com/index.php?rid=3839857&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00727.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839857 Fri, 30 Apr 2010 23:00:00 +0100 3839857 Cost‐Effectiveness of Nucleoside Analog Therapy for Hepatitis B in China: A Markov Analysis http://www.medworm.com/index.php?rid=3839856&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00733.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839856 Fri, 30 Apr 2010 23:00:00 +0100 3839856 The Impact of Value‐Based Benefit Design on Adherence to Diabetes Medications: A Propensity Score‐Weighted Difference in Difference Evaluation http://www.medworm.com/index.php?rid=3839855&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00730.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839855 Fri, 30 Apr 2010 23:00:00 +0100 3839855 Cost-Effectiveness of Nucleoside Analog Therapy for Hepatitis B in China: A Markov Analysis http://www.medworm.com/index.php?rid=3521850&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00733.x Conclusions: In China, when treating both HBeAg-positive and HBeAg-negative CHB populations, entecavir is the most cost-effective option when compared with lamivudine, adefovir, and telbivudine. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3521850 Fri, 30 Apr 2010 23:00:00 +0100 3521850 The Impact of Value-Based Benefit Design on Adherence to Diabetes Medications: A Propensity Score-Weighted Difference in Difference Evaluation http://www.medworm.com/index.php?rid=3521853&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00730.x Conclusion: A VBBD program that reduced the copayment for diabetes medications by 36.1% reduced the number of nonadherent patients by 30.0%. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3521853 Thu, 29 Apr 2010 23:00:00 +0100 3521853 Cost-Effectiveness of Therapeutic Hypothermia to Treat Neonatal Encephalopathy http://www.medworm.com/index.php?rid=3521852&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00731.x Conclusions: The probability that cooling is a cost-effective treatment for neonatal encephalopathy is finely balanced over the first 18 months after birth but increases substantially when national incidence data or an extended time horizon are considered. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3521852 Thu, 29 Apr 2010 23:00:00 +0100 3521852 Differences in Child versus Parent Reports of the Child's Health-Related Quality of Life in Children with Epilepsy and Healthy Siblings http://www.medworm.com/index.php?rid=3521851&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00732.x Conclusion: Children with epilepsy report HRQOL that is comparable to that of sibling controls, while parents rate children with epilepsy as having lower HRQOL than sibling controls. Measuring outcomes in studies of this population should incorporate both perspectives. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3521851 Thu, 29 Apr 2010 23:00:00 +0100 3521851 Cost-Effectiveness of Duloxetine: The Stress Urinary Incontinence Treatment (SUIT) Study http://www.medworm.com/index.php?rid=3500800&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00729.x Conclusions: Although the limitations of the use of SUIT's observational data for this purpose need to be acknowledged, the study suggests that initiating duloxetine therapy in SUI is a cost-effective treatment alternative. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3500800 Fri, 23 Apr 2010 23:00:00 +0100 3500800 Validation and Comparison of EuroQol and Short Form 6D in Chronic Prostatitis Patients http://www.medworm.com/index.php?rid=3474486&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00728.x Conclusions: Both EQ-5D and SF-6D are demonstrated to be valid and sensitive HRQoL measures in Chinese chronic prostatitis patients, with SF-6D showing better HRQoL dimension coverage, greater sensitivity, lower ceiling effect, and more rational distribution. Further research is needed to determine longitudinal response and reliability. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3474486 Thu, 15 Apr 2010 23:00:00 +0100 3474486 Small Budget Impact Is a Result of Flawed Assumptions and Ignores Questionable Cost-Effectiveness for RSV Prophylaxis http://www.medworm.com/index.php?rid=3474491&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00723.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3474491 Wed, 14 Apr 2010 23:00:00 +0100 3474491 A Review of Quantitative Risk–Benefit Methodologies for Assessing Drug Safety and Efficacy—Report of the ISPOR Risk–Benefit Management Working Group http://www.medworm.com/index.php?rid=3474490&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00725.x Conclusions: Several quantitative RBA methods are available that could be used to help lessen concern over subjective drug assessments and to help guide authorities toward more objective and transparent decision-making. When evaluating a new drug therapy, we recommend the use of multiple RBA approaches across different therapeutic indications and treatment populations in order to bound the risk[ndash]benefit profile. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3474490 Wed, 14 Apr 2010 23:00:00 +0100 3474490 Economic Implications of 21-Gene Breast Cancer Risk Assay from the Perspective of an Israeli-Managed Health-Care Organization http://www.medworm.com/index.php?rid=3474489&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00724.x Conclusion: Oncotype DX resulted in net QALY gain and increased overall costs, with an incremental cost-effectiveness ratio of $10,770. For CHS, Oncotype DX represents an effective and affordable approach to favorably affect the lives of women with ESBC. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3474489 Wed, 14 Apr 2010 23:00:00 +0100 3474489 Early-Stage Valuation of Medical Devices: The Role of Developmental Uncertainty http://www.medworm.com/index.php?rid=3474488&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00726.x Conclusions: A model based on two decision gates can lead to lower bounds (underestimates) for product value that can serve to support a decision to develop the product. Quantifiable uncertainty that can be resolved before the device is brought to market will generally enhance early-stage valuations of the device, and this remains true even when some components of uncertainty cannot be fully described. Clinical trials and other evidence-gathering activities undertaken as part of the development process can contribute to early-stage estimates of value. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3474488 Wed, 14 Apr 2010 23:00:00 +0100 3474488 General Population Reference Values for the French Version of the EuroQol EQ-5D Health Utility Instrument http://www.medworm.com/index.php?rid=3474487&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00727.x Conclusion: The EQ-5D performed as expected in a French-speaking general population sample. Reference values by sex and age group may facilitate the interpretation of results obtained in clinical settings. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3474487 Wed, 14 Apr 2010 23:00:00 +0100 3474487 Empirically Evaluating Decision‐Analytic Models http://www.medworm.com/index.php?rid=3839879&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00698.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839879 Wed, 31 Mar 2010 23:00:00 +0100 3839879 A Portuguese Value Set for the SF‐6D http://www.medworm.com/index.php?rid=3839878&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00701.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839878 Wed, 31 Mar 2010 23:00:00 +0100 3839878 Constructing a Conceptual Framework of Patient‐Reported Outcomes for Metastatic Hormone‐Refractory Prostate Cancer http://www.medworm.com/index.php?rid=3839877&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00702.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839877 Wed, 31 Mar 2010 23:00:00 +0100 3839877 Cost–Utility Analysis of Topical Intranasal Steroids for Otitis Media with Effusion Based on Evidence from the GNOME Trial http://www.medworm.com/index.php?rid=3839876&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00711.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839876 Wed, 31 Mar 2010 23:00:00 +0100 3839876 Network Meta‐Analysis: Importance of Appropriate Trial Selection http://www.medworm.com/index.php?rid=3839875&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00715.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839875 Wed, 31 Mar 2010 23:00:00 +0100 3839875 Response to Comments on “No Study Left Behind: A Network Meta‐Analysis in Non–Small‐Cell Lung Cancer Demonstrating the Importance of Considering All Relevant Data” http://www.medworm.com/index.php?rid=3839874&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00713.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839874 Wed, 31 Mar 2010 23:00:00 +0100 3839874 The Cost‐Effectiveness of Group Cognitive Behavioral Therapy Compared with Routine Primary Care for Women with Postnatal Depression in the UK http://www.medworm.com/index.php?rid=3839873&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00720.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839873 Wed, 31 Mar 2010 23:00:00 +0100 3839873 Incorporating Equity–Efficiency Interactions in Cost‐Effectiveness Analysis—Three Approaches Applied to Breast Cancer Control http://www.medworm.com/index.php?rid=3839872&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00718.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3839872 Wed, 31 Mar 2010 23:00:00 +0100 3839872 The Cost-Effectiveness of Group Cognitive Behavioral Therapy Compared with Routine Primary Care for Women with Postnatal Depression in the UK http://www.medworm.com/index.php?rid=3427552&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00720.x Conclusions: Given the current information, the use of gCBT does not appear to be cost-effective; however, this decision is uncertain. The value of information analyses conducted indicates that further research to provide robust information on key parameters is needed and appears justified in cost-effective terms. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3427552 Wed, 31 Mar 2010 23:00:00 +0100 3427552 Response to the Letter from Ms. Tamzin Furtado http://www.medworm.com/index.php?rid=3427556&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00716.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3427556 Tue, 30 Mar 2010 23:00:00 +0100 3427556 Abolition of Prescription Copayments in Wales: An Observational Study on Dispensing Rates http://www.medworm.com/index.php?rid=3427555&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00717.x Conclusions: The Welsh policy was associated with a modest increase in dispensing rates relative to NE England for the 14 medicines with the highest number of items dispensed subject to charge before abolition. Although factors besides the copayment may have influenced these observations, the smaller relative increase in total dispensing rates in Wales suggests that the overall impact of abolition was minimal. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3427555 Tue, 30 Mar 2010 23:00:00 +0100 3427555 Incorporating Equity–Efficiency Interactions in Cost-Effectiveness Analysis—Three Approaches Applied to Breast Cancer Control http://www.medworm.com/index.php?rid=3427554&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00718.x Conclusion: In the three equity weighing approaches, targeting women below 75 years of age was more cost-effective and led to more equitable distributions of health. This likely is similar in other fatal diseases with similar age distributions. The approaches may lead to different outcomes in nonfatal disease. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3427554 Tue, 30 Mar 2010 23:00:00 +0100 3427554 Response to: A Methodology for Successfully Producing Global Translations of Patient-Reported Outcomes Measures for Use in Multiple Countries by Two et al. http://www.medworm.com/index.php?rid=3427553&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00719.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3427553 Tue, 30 Mar 2010 23:00:00 +0100 3427553 Response to Comments on "No Study Left Behind: A Network Meta-Analysis in Non–Small-Cell Lung Cancer Demonstrating the Importance of Considering All Relevant Data" http://www.medworm.com/index.php?rid=3402045&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00713.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3402045 Thu, 25 Mar 2010 00:00:00 +0100 3402045 Network Meta-Analysis: Importance of Appropriate Trial Selection http://www.medworm.com/index.php?rid=3393545&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00715.x (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3393545 Tue, 23 Mar 2010 00:00:00 +0100 3393545 Tutorial in Medical Decision Modeling Incorporating Waiting Lines and Queues Using Discrete Event Simulation http://www.medworm.com/index.php?rid=3393552&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00707.x In most decision-analytic models in health care, it is assumed that there is treatment without delay and availability of all required resources. Therefore, waiting times caused by limited resources and their impact on treatment effects and costs often remain unconsidered. Queuing theory enables mathematical analysis and the derivation of several performance measures of queuing systems. Nevertheless, an analytical approach with closed formulas is not always possible. Therefore, simulation techniques are used to evaluate systems that include queuing or waiting, for example, discrete event simulation. To include queuing in decision-analytic models requires a basic knowledge of queuing theory and of the underlying interrelationships. This tutorial introduces queuing theory. Analysts and decisi... Value in Health journals http://www.medworm.com/rss/comments.php?id=3393552 Mon, 22 Mar 2010 00:00:00 +0100 3393552 Assessing the Economic Value of Public Health Programs Based on Risk: The Case of the Cancer Plan in France http://www.medworm.com/index.php?rid=3393551&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00708.x Conclusions: The proposed classification of health risk components gives more insight and understanding of risks associated with diseases and illness and proposes an operational representation of actions and costs related to the risks. The methodology proposed might be of significant interest to those involved in making health-care financing decisions. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3393551 Mon, 22 Mar 2010 00:00:00 +0100 3393551 Eliciting Distributions to Populate Decision Analytic Models http://www.medworm.com/index.php?rid=3393550&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00709.x Conclusion: Elicitation offers a feasible method to generate evidence for the missing information but there are a number of key issues for which further research is required. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3393550 Mon, 22 Mar 2010 00:00:00 +0100 3393550 Projecting the Effect of Nesiritide on Dialysis and Hospital Mortality in Cardiac Surgery Patients http://www.medworm.com/index.php?rid=3393549&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00710.x Conclusion: If the demonstrated renal preservation can be extrapolated, nesiritide may reduce dialysis and hospital death in cardiac surgery patient with preoperative RD, but to a much lesser extent or not in patients with normal preoperative renal function. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3393549 Mon, 22 Mar 2010 00:00:00 +0100 3393549 Cost–Utility Analysis of Topical Intranasal Steroids for Otitis Media with Effusion Based on Evidence from the GNOME Trial http://www.medworm.com/index.php?rid=3393548&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00711.x Conclusions: Topical steroids are unlikely to be a cost-effective treatment for OME in general practice. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3393548 Mon, 22 Mar 2010 00:00:00 +0100 3393548 Distributions of Parameters for Uncertainty Analysis Cannot Be Defined without Using Prior Information http://www.medworm.com/index.php?rid=3393547&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00712.x Conclusion: Defining the distribution of a RR or any other model parameter without being a Bayesian is epistemologically impossible. This means that being explicit on prior distributions used for deriving those distributions, and justifying them, is a necessary part of suggesting new ways to define distributions. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3393547 Mon, 22 Mar 2010 00:00:00 +0100 3393547 Evaluating Interventions to Improve Antiretroviral Adherence: How Much of an Effect Is Required for Favorable Value? http://www.medworm.com/index.php?rid=3393546&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00714.x Conclusions: ARV adherence interventions with plausible effect sizes may offer favorable value if they cost (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3393546 Mon, 22 Mar 2010 00:00:00 +0100 3393546 Consequences of Screening in Lung Cancer: Development and Dimensionality of a Questionnaire http://www.medworm.com/index.php?rid=3361537&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00697.x Conclusion: In conclusion, the reliability and the dimensionality of a condition-specific measure with high content validity for persons having abnormal or false-positive lung cancer screening results have been demonstrated. This new questionnaire called Consequences of Screening in Lung Cancer (COS-LC) covers in two parts the psychosocial experience in lung cancer screening. Part I: "anxiety,""behavior,""dejection,""sleep,""self-blame,""focus on airway symptoms,""stigmatization,""introvert," and "harm of smoking." Part II: "calm/relax,""social network,""existential values,""impulsivity,""empathy," and "regretful of still smoking." (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3361537 Sat, 13 Mar 2010 00:00:00 +0100 3361537 International Development of the Unidimensional Fatigue Impact Scale (U-FIS) http://www.medworm.com/index.php?rid=3357496&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00706.x Conclusion: The U-FIS is a practical new measure of the impact of fatigue. It was successfully adapted into eight new languages to broaden availability for researchers. Psychometric analyses indicated that the new language versions were unidimensional and reproducible with promising construct validity. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3357496 Fri, 12 Mar 2010 00:00:00 +0100 3357496 Constructing a Conceptual Framework of Patient-Reported Outcomes for Metastatic Hormone-Refractory Prostate Cancer http://www.medworm.com/index.php?rid=3353076&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00702.x Conclusion: Findings were used to propose a conceptual framework of PROs for metastatic HRPC. Such frameworks can be used to help specify targets for assessment in clinical studies such as treatment trials. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3353076 Thu, 11 Mar 2010 00:00:00 +0100 3353076 Quantifying Women's Stated Benefit–Risk Trade-Off Preferences for IBS Treatment Outcomes http://www.medworm.com/index.php?rid=3353082&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00694.x Conclusions: Variation in MARs across AE types is consistent with the relative seriousness of the AEs. Stated-preference methods offer a scientifically valid approach to quantifying benefit[ndash]risk trade-off preferences that can be used to inform regulatory decision-making. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3353082 Wed, 10 Mar 2010 00:00:00 +0100 3353082 Analysis of Health Utility Data When Some Subjects Attain the Upper Bound of 1: Are Tobit and CLAD Models Appropriate? http://www.medworm.com/index.php?rid=3353081&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00695.x Conclusions: When the intention of the analysis is to inform an economic evaluation, and the utilities should be bounded above at 1, CLAD, and Tobit methods were biased. OLS coupled with robust standard errors or the nonparametric bootstrap is recommended as a simple and valid approach. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3353081 Wed, 10 Mar 2010 00:00:00 +0100 3353081 The Suitability of Polycystic Ovary Syndrome-Specific Questionnaires for Measuring the Impact of PCOS on Quality of Life in Clinical Trials http://www.medworm.com/index.php?rid=3353080&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00696.x Conclusions: The PCOSQ is the only condition-specific measure of the impact of PCOS on QoL. Additional research is required to ensure its comprehensiveness, sensitivity, and to guide interpretation prior to including in clinical trials. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3353080 Wed, 10 Mar 2010 00:00:00 +0100 3353080 Empirically Evaluating Decision-Analytic Models http://www.medworm.com/index.php?rid=3353079&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00698.x Conclusions: To support external and projective validity, cost-effectiveness models should be iteratively evaluated as new studies become available, with reporting standardized to facilitate assessment. Such evaluations are particularly relevant for models used to conduct comparative effectiveness analyses. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3353079 Wed, 10 Mar 2010 00:00:00 +0100 3353079 Populating an Economic Model with Health State Utility Values: Moving toward Better Practice http://www.medworm.com/index.php?rid=3353078&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00700.x Conclusion: Although further research in additional health conditions is required to support our findings, our results highlight the need for analysts to conform to an agreed reference case. We demonstrate that in CVD, if data are not available from individuals without the health condition, HSUVs from the general population provide a reasonable approximation. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3353078 Wed, 10 Mar 2010 00:00:00 +0100 3353078 A Portuguese Value Set for the SF-6D http://www.medworm.com/index.php?rid=3353077&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2010.00701.x Conclusion: The models estimated provide preference-based quality of life weights for the Portuguese population when health status data have been collected using the SF-36. Although the sample was randomly drowned findings should be treated with caution, given the small sample size, even knowing that they have been estimated at the individual level. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3353077 Wed, 10 Mar 2010 00:00:00 +0100 3353077 Impact of Waist Circumference Difference on Health-Care Cost among Overweight and Obese Subjects: The PROCEED Cohort http://www.medworm.com/index.php?rid=3210924&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2009.00690.x Conclusions: Targeting people with a high waist circumference for weight management whether they are overweight or obese may maximize cost-efficacy. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3210924 Wed, 27 Jan 2010 00:00:00 +0100 3210924 Treatment Patterns and Adherence among Patients with Chronic Hepatitis C Virus in a US Managed Care Population http://www.medworm.com/index.php?rid=3196540&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2009.00691.x Conclusions: New and improved treatments that promote better adherence and impose a lower cost burden on patients and payers are needed. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3196540 Fri, 22 Jan 2010 00:00:00 +0100 3196540 Cost–Effectiveness of Osteoporosis Screening Followed by Treatment: The Impact of Medication Adherence http://www.medworm.com/index.php?rid=3196543&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2009.00687.x Conclusion: This study indicates that nonadherence with osteoporosis medications substantially increases the incremental cost[ndash]effectiveness ratio of osteoporosis screening strategies. All aspects of medication adherence (i.e., compliance, persistence, and primary adherence) should therefore be reported and included in pharmacoeconomic analyses, and especially in the presence of the upfront cost of case finding (such as screening cost). (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3196543 Thu, 21 Jan 2010 00:00:00 +0100 3196543 Assessing Outcomes in Liver Disease Patients: Reliability and Validity of the Spanish Version of the Liver Disease Quality of Life Questionnaire (LDQOL 1.0) http://www.medworm.com/index.php?rid=3196542&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2009.00688.x Conclusions: The Spanish version of the LDQOL 1.0 has shown satisfactory reliability and validity. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3196542 Thu, 21 Jan 2010 00:00:00 +0100 3196542 Application of the Disease-Specific Quality of Life Assessment of Growth Hormone Deficiency in Adults (QoL-AGHDA) Questionnaire in a General Population: Results from a French Panel Study http://www.medworm.com/index.php?rid=3196541&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2009.00689.x Conclusions: The QoL-AGHDA questionnaire showed good psychometric properties when administered in the French population. French reference values were collected, completing the QoL-AGHDA normative database already available in several European countries. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3196541 Thu, 21 Jan 2010 00:00:00 +0100 3196541 Patient Expectations and Health-Related Quality of Life Outcomes Following Total Joint Replacement http://www.medworm.com/index.php?rid=3178000&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2009.00685.x Conclusions: Patients have high expectations for the benefits of TJR, and those who fulfill their expectations have greater gains in HRQoL assessing by SF-12, WOMAC and EQ-5D. Health-care providers should help their patients develop realistic expectations about the impact of TJR. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3178000 Sat, 16 Jan 2010 00:00:00 +0100 3178000 Transferability of Model-Based Economic Evaluations: The Case of Trastuzumab for the Adjuvant Treatment of HER2-Positive Early Breast Cancer in the Netherlands http://www.medworm.com/index.php?rid=3178002&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2009.00683.x Conclusion: Transferability of a model-based UK-study in three steps proved to be an efficient method to provide an early indication of the cost[ndash]effectiveness of trastuzumab and has led to the provisional reimbursement of the treatment. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3178002 Fri, 15 Jan 2010 00:00:00 +0100 3178002 Dimensionality and Summary Measures of the SF-36 v1.6: Comparison of Scale- and Item-Based Approach Across ECRHS II Adults Population http://www.medworm.com/index.php?rid=3178001&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2009.00684.x Conclusions: We were able to confirm the hypothesized dimensionality of eight scales and two summaries of the SF-36. The alternative scoring reaches at least the same required standards of the original scoring. In addition, it can reduce the item-scale inconsistencies without loss of predictive validity. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3178001 Fri, 15 Jan 2010 00:00:00 +0100 3178001 An Evaluation of the Cost-Effectiveness of Rituximab in Combination with Chemotherapy for the First-Line Treatment of Follicular Non-Hodgkin's Lymphoma in the UK http://www.medworm.com/index.php?rid=3155348&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2009.00676.x Conclusions: The addition of rituximab to chemotherapy in advanced FL was found to be highly cost-effective in the UK. (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3155348 Fri, 08 Jan 2010 00:00:00 +0100 3155348 Effects of Method of Translation of Patient-Reported Health Outcome Questionnaires: A Randomized Study of the Translation of the Rheumatoid Arthritis Quality of Life (RAQoL) Instrument for Sweden http://www.medworm.com/index.php?rid=3155347&cid=s_31008_46_f&fid=31008&url=http%3A%2F%2Fdx.doi.org%2F10.1111%252Fj.1524-4733.2009.00677.x Conclusions: The DP approach showed advantages over FB translation in terms of preference by the target population and by lay people, whereas there were no obvious psychometric differences. This suggests advantages of DP over FB translation from the patients' perspective, and does not support the commonly held view that FB translation is the "gold standard." (Source: Value in Health) Value in Health journals http://www.medworm.com/rss/comments.php?id=3155347 Fri, 08 Jan 2010 00:00:00 +0100 3155347