MedWorm.com provides a medical RSS filtering service. Over 6000 RSS medical sources are combined and output via different filters. This feed contains the latest items from the 'World Journal of Surgical Oncology' source. Wed, 08 Feb 2012 08:42:01 +0100 http://www.medworm.com/index.php?rid=5666735&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F10%2F1%2F31 Conclusions: In this older population, laparoscopic colectomy practice patterns were associated with factors which likely correlate with tertiary referral centers. Although short-term and long-term survival are comparable, laparoscopic colectomy offers shorter hospitalizations and less intensive care. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5666735 Tue, 07 Feb 2012 05:00:00 +0100 5666735 http://www.medworm.com/index.php?rid=5666737&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F10%2F1%2F29 Conclusions: High-pressure intrapleural chemotherapy is feasible in pigs. Further experiments will establish the pharmacokinetics and determine whether the benefit already shown in the peritoneum is also obtained in the pleura. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5666737 Mon, 06 Feb 2012 05:00:00 +0100 5666737 http://www.medworm.com/index.php?rid=5666736&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F10%2F1%2F30 This report describes a case of 60-year-old man who had undergone radiotherapy two years earlier for a recurrent rectal tumor and presented with small bowel obstruction. A spacer was used before radiotherapy. Radiological assessment and laparotomy revealed the presence of the spacer inside the small bowel lumen. It is possible that the spacer established contact with the intestine, elicited local inflammatory reaction that facilitated the complete penetration of the intestinal wall without causing any clinical symptoms. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5666736 Mon, 06 Feb 2012 05:00:00 +0100 5666736 http://www.medworm.com/index.php?rid=5659386&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F10%2F1%2F28 Conclusions: :Liposarcomas do not express E-cadherin, which matches the absence of epithelioid differentiation in this sarcoma subtype, and have low topoisomerase II-alpha expression, which justifies to some extend their resistance to anthracycline-based chemotherapy. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5659386 Thu, 02 Feb 2012 05:00:00 +0100 5659386 http://www.medworm.com/index.php?rid=5647026&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F10%2F1%2F27 Conclusions: Foveolar hyperplasia was associated with the severity of bile reflux, suggesting that it is a histological feature of primary BRG in children, while vascular congestion may be a protective factor. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5647026 Tue, 31 Jan 2012 05:00:00 +0100 5647026 http://www.medworm.com/index.php?rid=5638045&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F10%2F1%2F26 We present one case with symptoms of paroxysmal abdominal pain for over 20 days. Abdominal computerized tomography (CT) scan revealed intestinal obstruction and a mass of 6.0cmx6.0cm in size located at left adrenal. Chest CT scan showed a lobulated mass of 2.7cmx2.7cm in size at the upper left lung. Core needle biopsy of the lung mass confirmed the diagnosis of large cell carcinoma. The patient underwent an emergency abdominal laparotomy and received chemotherapy regimen consisted of pemetrexed and cisplatin postoperatively. In addition, we made a review of literature about its occurrence, diagnosis and outcome. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5638045 Sun, 29 Jan 2012 05:00:00 +0100 5638045 http://www.medworm.com/index.php?rid=5638047&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F10%2F1%2F24 Isolated splenic metastasis from lung cancer is a very rare occurrence with only a few reports available. Here, we report the case of a 82-year-old male who underwent a bilobectomy for a lung squamous cell carcinoma and 16 months later developed an isolated splenic metastasis. Additionally, previous reports are reviewed and discussed. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5638047 Fri, 27 Jan 2012 05:00:00 +0100 5638047 http://www.medworm.com/index.php?rid=5638046&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F10%2F1%2F25 Conclusion: Incidental abdominal findings in the colon on FDG-PET scan for work-up of pulmonary nodules need to be further investigated by colonoscopy. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5638046 Fri, 27 Jan 2012 05:00:00 +0100 5638046 http://www.medworm.com/index.php?rid=5638048&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F10%2F1%2F23 Liver angiosarcoma is a rare disease, however it still ranks as the third of most common primary liver maligancies. The prognosis of liver angiosarcoma is very poor with almost all patients with this kind of disease die within 2 years after diagnosis. No specific symptoms and signs are closely associated with this disease. Here, we report a case presenting shock status at first due to rupture of liver angiosarcoma- induced internal bleeding. After emergent transarterial embolization (TAE), she received partial hepatectomy two weeks later. 4 months after operation, she is still with a good performance status without obvious recurrence or metastasis identified. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5638048 Thu, 26 Jan 2012 05:00:00 +0100 5638048 http://www.medworm.com/index.php?rid=5628112&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F10%2F1%2F22 Conclusion: The separation method of the hepatic arteries, portal veins, and bile duct is safe and feasible for a liver cancer patient with portal vein tumor thrombus. Modified selective hepatic vascular exclusion was useful to control bleeding during liver transection. Anatomical liver segmentectomy 2 using these procedures should be considered for a patient with a liver tumor located at segment 2 arising from a damaged liver. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5628112 Wed, 25 Jan 2012 05:00:00 +0100 5628112 http://www.medworm.com/index.php?rid=5628114&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F10%2F1%2F20 Conclusions: This method is considered to serve as a useful technique for gastric conduit elevation.Key Words: Esophagectomy, Gastric conduit elevation, Echo probe cover (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5628114 Tue, 24 Jan 2012 05:00:00 +0100 5628114 http://www.medworm.com/index.php?rid=5628113&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F10%2F1%2F21 We reported two cases of medically refractory THPP with recurrent paralysis of extremities and hypokalemia, and both were combined with thyroid nodules. Both patients were treated with total thyroidectomy; the pathology revealed that one is Graves' disease with thyroid papillary carcinoma, and the other is adenomatous goiter with papillary hyperplasia. No episode of periodic paralysis was noted and laboratory evaluation revealed normal potassium level during the post-operative follow up. Our experience suggests that total thyroidectomy by experienced surgeon is an appropriate and definite treatment for medically refractory THPP, especially in cases combined with thyroid nodules. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5628113 Tue, 24 Jan 2012 05:00:00 +0100 5628113 http://www.medworm.com/index.php?rid=5628115&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F10%2F1%2F19 Conclusion: The use of several immunohistochemical markers, careful evaluation of hematoxylin-eosin sections and the Ki-67 labelling index are important tools in discriminating between carcinoids and other bronchopulmonary carcinomas. Although we could not detect GnrH-receptors in the examined specimen, there may be individual differences in expression. GnrH receptor profiles in typical and atypical carcinoids should be scrutinized. This could lead to new therapeutical options, since the GnrH receptor has already been described on atypical carcinoids. Clinically tested drugs such as leuprolide could come to use. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5628115 Mon, 23 Jan 2012 05:00:00 +0100 5628115 http://www.medworm.com/index.php?rid=5619648&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F10%2F1%2F18 Conclusions: The results of our survey demonstrate that the majority of respondents feel that the current educational environment for Oncology in India should be enhanced. The study identified perceptions of several gaps and needs, which can be the targets for implementing measures to enhance the training of Oncology professionals. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5619648 Mon, 23 Jan 2012 05:00:00 +0100 5619648 http://www.medworm.com/index.php?rid=5619650&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F10%2F1%2F16 Conclusions: This is the first reported case of radical resection of a lung cancer with invasion along the pulmonary artery wherein a benign thrombus had formed. In general, surgery would be the treatment of choice for a pulmonary artery mass. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5619650 Sat, 21 Jan 2012 05:00:00 +0100 5619650 http://www.medworm.com/index.php?rid=5619649&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F10%2F1%2F17 Meningiomas are common neoplasms arising from the central nervous system meninges. On the other hand, primary ectopic meningiomas are extremely rare and usually limited to the head and neck region or to the paravertebral soft tissues. Their occurrence in the mediastinum is even rarer. Until now, only 4 cases of primary mediastinal meningioma have been reported in the literature searched on Medline. Because of its rarity and intriguing pathogenesis, we report here a case of primary mediastinal meningioma that was treated by surgical resection. The clinical features, treatment, pathological findings, and prognosis are analyzed, and the literature based on ectopic meningioma is reviewed. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5619649 Sat, 21 Jan 2012 05:00:00 +0100 5619649 http://www.medworm.com/index.php?rid=5608102&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F10%2F1%2F15 Conclusions: This largest ever series from India compares favorably with global standards. In a nation where colorectal cancer is on the rise, it is imperative that high volume centers develop specialized units to train future specialist colorectal surgeons. This would ensure improved quality assurance and delivery of health care even to outreach, low volume centers. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5608102 Wed, 18 Jan 2012 05:00:00 +0100 5608102 http://www.medworm.com/index.php?rid=5608103&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F10%2F1%2F14 Conclusions: Adenocarcinoma of esophagogastric junction rarely presents EGFR mutation, especially gefitinib-associated mutations such as L858R or delE746-A750. This means that the gefitinib-based gene target therapy should not be recommended for treating carcinoma of esophagogastric junction. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5608103 Tue, 17 Jan 2012 05:00:00 +0100 5608103 http://www.medworm.com/index.php?rid=5596890&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F10%2F1%2F12 We describe the case of a 38-year-old premenopausal woman who presenting with a mass in the left breast. Mammography revealed an oval mass that was partly indistinct, and ultrasonography showed a hypoechoic mass with a slightly irregular margin. Bilateral breast dynamic magnetic resonance imaging was performed for a more detailed evaluation. The images showed rapid initial enhancement and a microlobulated margin. Because the suspicion of malignancy was strong at that time, core needle biopsy was performed. Histologically, the tumor was identified as fibroadenoma. A case of myoid hamartoma of the breast that proved difficult to diagnose is reported, and discussed with reference to the literature. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5596890 Mon, 16 Jan 2012 05:00:00 +0100 5596890 http://www.medworm.com/index.php?rid=5596889&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F10%2F1%2F13 We report two clinical cases of primary granulocytic sarcoma of the pancreas that were diagnosed on the surgical specimen. Atypical clinical and morphological presentations may have lead to pretherapeutic biopsies of the pancreatic mass in order to indicate primary chemotherapy. Literature review of this rare clinical presentation may help physicians to anticipate diagnostic and therapeutic strategies. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5596889 Mon, 16 Jan 2012 05:00:00 +0100 5596889 http://www.medworm.com/index.php?rid=5580984&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F10%2F1%2F11 Conclusion: These data show that RNAa-mediated overexpression of WT1 may have therapeutic potential in the treatment of hepatocellular carcinoma. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5580984 Fri, 13 Jan 2012 05:00:00 +0100 5580984 http://www.medworm.com/index.php?rid=5580986&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F10%2F1%2F9 Conclusions: Completeness of resection, nodal status, depth of invasion, tumor size, and adjuvant chemotherapy were prognostic factors for long-term survival in NSCLC patients with chest wall invasion. Because of poor prognosis in cases with chest wall invasion that have N2 positive LN, that is difficult to achieve complete resection and that need pneumonectomy, definite chemoradiotherapy or neoadjuvant chemoradiotherapy should be considered first in these cases. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5580986 Thu, 12 Jan 2012 05:00:00 +0100 5580986 http://www.medworm.com/index.php?rid=5580985&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F10%2F1%2F10 Both intraparenchymal papillary meningioma and papillary meningioma with cyst formation of brainstem have never been reported. The authors present an extremely rare case of patient with intraparenchymal papillary meningioma of brainstem. A 23-year-old Chinese male presented with a 4-month history of progressive left upper limb and facial nerve palsy. Magnetic resonance imaging revealed a cystic-solid, heterogeneously enhancing mass in pons and right cerebral peduncle with no dural attachment. The tumor was totally removed via subtemporal approach. During surgery, the lesion was found to be completely intraparenchymal. Histological and immunohistochemical examinations were compatible with the diagnosis of papillary meningioma. The lesion recurred nine months after primary surgery, a second ... World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5580985 Thu, 12 Jan 2012 05:00:00 +0100 5580985 http://www.medworm.com/index.php?rid=5580988&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F10%2F1%2F7 Conclusion: With this report the authors have demonstrated that the spread of cervical adenocarcinoma to the uterine corpus, although rare, may be observed, and that in this instance immunohistochemical and molecular studies can provide sufficient information fo accurate diagnosis even on small biopsy specimens. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5580988 Wed, 11 Jan 2012 05:00:00 +0100 5580988 http://www.medworm.com/index.php?rid=5580987&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F10%2F1%2F8 Conclusions: The mastectomy flap fixation technique is a valuable procedure that significantly decreases the incidence of seroma formation, and reduces the duration and amount of drained fluid. However, it should be tried on a much wider scale to prove its validity.Key Words: mastectomy, flap, fixation, seroma (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5580987 Wed, 11 Jan 2012 05:00:00 +0100 5580987 http://www.medworm.com/index.php?rid=5580990&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F10%2F1%2F5 Background To study the methylation status of genes that play a role in the p53-Bax mitochondrial apoptosis pathway and its clinical significance in cholangiocarcinoma.Patients and Methods Out of 36 cases cholangiocarcinoma patients from April 2000 to May 2005 were collected.Promoter hypermethylation of DAPK, p14ARF, and ASC were detected by methylation-specific PCR on cholangiocarcinoma and normal adjacent tissues samples. Mutation of the p53 gene was examined by automated sequencing. Correlation between methylation of these genes and/or p53 mutation status with clinical characteristics of patients was investigated by statistical analysis.Results We found 66.7% of 36 cholangiocarcinoma patients had methylation of at least one of the tumor suppressor genes analyzed. p53 gene mutation was f... World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5580990 Mon, 09 Jan 2012 05:00:00 +0100 5580990 http://www.medworm.com/index.php?rid=5580989&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F10%2F1%2F6 Conclusions: Although it is not easy to speculate on the coexistence of adenocarcinoma and GIST, pre-and post-operative diagnoses may be essential, and such cancer development is not considered to be unusual. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5580989 Mon, 09 Jan 2012 05:00:00 +0100 5580989 http://www.medworm.com/index.php?rid=5580991&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F10%2F1%2F4 Conclusions: Organ-specific metastasis may depend on the molecular subtype of breast cancer. Tailored strategies against distant metastasis concerning the molecular subtypes in breast cancer may be considered. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5580991 Sun, 08 Jan 2012 05:00:00 +0100 5580991 http://www.medworm.com/index.php?rid=5571933&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F10%2F1%2F3 Conclusions: This study illustrates that this new suicide gene system mediated by G5-PAMAM-D is effective in decreasing PC-3 cell proliferation and inducing cell apoptosis, and inhibiting tumor growth in vivo. In a word, our study could provide a potential approach for gene therapy of prostate cancer. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5571933 Sun, 08 Jan 2012 05:00:00 +0100 5571933 http://www.medworm.com/index.php?rid=5571934&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F10%2F1%2F2 Conclusions: Hepatic malignant fibrous histiocytoma is a rare malignant mesenchymal tumor. The variable features of clinical presentations and images make the diagnosis difficult. Though the prognosis of primary hepatic malignant fibrous histiocytoma was rather poor, integrated resection might provide a few cases a good opportunity for surviving, suggesting that surgery might be an effective treatment. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5571934 Thu, 05 Jan 2012 05:00:00 +0100 5571934 http://www.medworm.com/index.php?rid=5559415&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F10%2F1%2F1 Conclusion: We found that neoadjuvant chemohormonal therapy with complete androgen blockade followed by treatment with docetaxel and estramustine phosphate before radical prostatectomy was safe, feasible, and associated with favorable pathological outcomes in patients with a high risk of localized PCa. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5559415 Wed, 04 Jan 2012 05:00:00 +0100 5559415 http://www.medworm.com/index.php?rid=5552007&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F174 Conclusion: The incidence of CRC recurrence after LR for hepatic metastasis remains very high. However, the management and outcomes of patients with CRC hepatic metastasis have greatly improved with time, suggesting that the current use of aggressive multimodality treatments including surgical resection combined with modern chemotherapeutic regimens effectively prolongs the life expectancy of these patients. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5552007 Fri, 30 Dec 2011 05:00:00 +0100 5552007 http://www.medworm.com/index.php?rid=5552008&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F173 Persistent left superior vena cava (PLSVC) represents the most common congenital venous anomaly of the thoracic systemic venous return, occurring in 0.3% to 0.5% of individuals in the general population, and in up to 12% of individuals with other documented congential heart abnormalities. In this regard, there is very little in the literature that specifically addresses the potential importance of the incidental finding of PLSVC to surgeons, interventional radiologists, and other physicians actively involved in central venous access device placement in cancer patients. In the current review, we have attempted to comprehensively evaluate the available literature regarding PLSVC. Additionally, we have discussed the clinical implications and relevance of such congenital aberrancies, as well a... World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5552008 Wed, 28 Dec 2011 05:00:00 +0100 5552008 http://www.medworm.com/index.php?rid=5537455&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F172 Background: The significance of carcinoembryonic antigen-related cell adhesion molecule 7 (CEACAM7) expression in gastric carcinoma and precancerous lesions and its correlation with CEA expression has rarely been previously investigated. Methods: CEACAM7 and CEA expression was detected by immunohistochemistry in consecutive sections of 345 subjects with gastric carcinoma and precancerous lesions. Laser confocal analysis was performed to determine CEACAM7 and CEA localization. Correlation between CEACAM7 and CEA expression with clinicopathological parameters was statistically analyzed. Results: CEACAM7 expression correlated with pathologic grading (P=0.006), Lauren's classification (P=0.023), and CEA expression (Spearman R=0.605, P (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5537455 Fri, 23 Dec 2011 05:00:00 +0100 5537455 http://www.medworm.com/index.php?rid=5524109&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F170 Conclusions: Patients underwent lobectomy by VATS have better compliance and fewer delayed or reduced dose on adjuvant chemotherapy than those by thoracotomy. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5524109 Wed, 21 Dec 2011 05:00:00 +0100 5524109 http://www.medworm.com/index.php?rid=5524108&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F171 Conclusion: Computer Tomography represents an effective procedure in the preoperative staging of patients with PC. However, results by abdominopelvic region show lower correlation, therefore suggest lower efficacy. These results are supported by analyses of sensitivity and accuracy by lesion size. This suggests that Computer Tomography is an effective procedure for pre-operative staging but less for determining a tumor's accurate extent. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5524108 Wed, 21 Dec 2011 05:00:00 +0100 5524108 http://www.medworm.com/index.php?rid=5524110&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F169 Conclusion The degree of organ support required post-operatively is minimal. Early extubation is efficacious with the aid of epidural analgesia. Critical Care monitoring for 48 hours is desirable in view of the post-operative challenges. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5524110 Mon, 19 Dec 2011 05:00:00 +0100 5524110 http://www.medworm.com/index.php?rid=5504322&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F167 Conclusion: The present investigation indicated increased expression of PPARalpha mRNA and mRNAs for PPARalpha target genes in human hepatocellular carcinoma. These results might be associated with its carcinogenesis and characteristic features of energy production. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5504322 Thu, 15 Dec 2011 05:00:00 +0100 5504322 http://www.medworm.com/index.php?rid=5504321&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F168 Littoral cell angioma (LCA) is a rare splenic vascular neoplasm that arises from the cells lining the red pulp sinuses. It is deemed to be a benign and incidental lesion. The earliest literature report of littoral cell angioma has been described by Falk. The examination of samples after splenectomy reveals similar pathological change and its change rule is summarized. However, many recent reports have described it to be a malignant tumor with congenital and immunological associations. Generally speaking, the definitive diagnosis can only be made after histological and immunohistochemical profiles. In this case report, we presented the case of a 48-year-old woman with multiple splenic LCAs. Initially, the patient was characteristics of abdominal distension, weakness and fatigue. Multiple he... World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5504321 Thu, 15 Dec 2011 05:00:00 +0100 5504321 http://www.medworm.com/index.php?rid=5504324&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F165 We report a patient with WG in whom a CT scan revealed an infiltrating mass in the lower portion of the left kidney. After surgical exploration, we performed an open radical nephrectomy. Histopathology showed clear cell type renal cell carcinoma (RCC). RCC associated with WG has been reported in only a few cases, and in most of them, the diseases started simultaneously, suggesting common pathogenetic pathways. Long-term immunosuppressive treatment is a known risk factor in the development of malignancies, so occurrence of RCC in WG has been proposed as a side effect of cyclophosphamide treatment. Furthermore, it is important to make a differential diagnosis between RCC and pseudotumors in WG as they cannot be distinguished solely on basis of imaging findings. Due to the higher risk of urol... World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5504324 Tue, 13 Dec 2011 05:00:00 +0100 5504324 http://www.medworm.com/index.php?rid=5504323&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F166 Background: Recent studies have shown that disruption of circadian rhythms is one of the tumor promoting factors which contribute to mammalian cancer development and progression, but very little is known about the molecular changes of circadian genes in colorectal carcinoma (CRC). Thus, in this study, changes in the expression of human Period2 (hPer2), one of the key circadian clock regulators, in CRC and its correlation with prognosis were investigated. Methods: Immunohistochemical (IHC) staining and real-time PCR for hPer2 were performed for 38 CRC cases. Results: IHC analysis detected positive staining for hPer2 in 81.6(31/38) of CRC tissues and 97.4(37/38) of surrounding non-cancerous tissues (P (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5504323 Tue, 13 Dec 2011 05:00:00 +0100 5504323 http://www.medworm.com/index.php?rid=5486414&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F163 We report a case of primary clear cell sarcoma occurring in the humerus. A 20 year old girl was referred to our hospital two years ago with painless swelling of the soft tissue surrounding the proximal right humerus. The conventional radiographic image showed an ill-defined, aggressive, osteolytic lesion associated with a partial cortical defect of the proximal right humerus. Magnetic resonance imaging found an irregularly shaped extraosseous mass extending from the proximal shaft of the right humerus, penetrating through the destroyed bone and invading the biceps brachii. After preoperative chemotherapy, a total tumor resection, internal fixation and bone cement implantation were performed. Histological studies of the resected tumor found that fibrous septa divided into well-defined nests... World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5486414 Fri, 09 Dec 2011 05:00:00 +0100 5486414 http://www.medworm.com/index.php?rid=5486413&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F164 Background: Gallbladder carcinoma (GC) is a relatively rare malignancy worldwide but is the second commonest gastrointestinal cancer in Pakistani women. Gallstones have a positive association with GC but other associated risk factors have been identified. Methods: This is a retrospective case control study over a period of 19 years. The cases (Group A) were patients with histopathological proven carcinoma gallbladder (N=60) and controls were patients with cholelithiasis but no carcinoma gallbladder on histopathology (N=120). Multivariate regression analysis was done to calculate the odds ratio, 95% confidence interval and P-Value. A positive relationship was found between size of stone >1cm, solitary stone, age > 55 years and multi-parity in women. Results: There were 60 patients in Group ... World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5486413 Fri, 09 Dec 2011 05:00:00 +0100 5486413 http://www.medworm.com/index.php?rid=5486415&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F162 Conclusion: SILC can successfully and safely be performed with standard laparoscopic instruments. This technique might be an alternative procedure to conventional laparoscopic colectomy with better cosmetic result. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5486415 Wed, 07 Dec 2011 05:00:00 +0100 5486415 http://www.medworm.com/index.php?rid=5476140&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F161 A 71-year-old man suddenly developed abdominal pain and vomiting on drinking soda after a meal, and visited a physician. Cervical subcutaneous and mediastinal emphysemas were observed on CT, and the patient was transferred to the emergency medical center of our hospital on the same day. Esophagography was performed at our department. A ruptured region was identified on the left side of the lower thoracic esophagus, and surgery was emergently performed employing sequential left thoracoabdominal incision. The chest wall was adhered due to inflammation, and large amounts of residual food and sloughing were present in the thoracic cavity and mediastinum. Moreover, necrotic changes were noted in the superior through inferior mediastinum. An about 2-cm rupture site was confirmed on the left side... World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5476140 Tue, 06 Dec 2011 05:00:00 +0100 5476140 http://www.medworm.com/index.php?rid=5476142&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F159 Conclusion: This oncoplastic volume replacement technique obtained a good local control and satisfactory and stable aesthetic results which have maintained unchanged after a long period of time. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5476142 Mon, 05 Dec 2011 05:00:00 +0100 5476142 http://www.medworm.com/index.php?rid=5476141&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F160 Conclusions: Unplanned resection lead to a relatively worse prognosis and a likelihood of recurrence despite additional resections. We recommend that soft tumors of the foot should only be excised after appropriate preoperative evaluation regardless of the size of the tumor. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5476141 Mon, 05 Dec 2011 05:00:00 +0100 5476141 http://www.medworm.com/index.php?rid=5468388&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F157 Conclusions: This method using ICG fluorescence imaging may possibly improve the detection rate of sentinel lymph nodes with high sensitivity and compensates for the deficiencies of other methods. The ICG fluorescence imaging technique enables observation of breast lymph vessels running in multiple directions and easily and accurately identification of sentinel lymph nodes. Thus, this technique can be considered useful. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5468388 Fri, 02 Dec 2011 05:00:00 +0100 5468388 http://www.medworm.com/index.php?rid=5468387&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F158 Conclusions: Heparanase contributes to angiogenesis of ccRCC and over-expression of heparanase is an independent predictors of prognosis for ccRCC. MVD is correlated with tumor development and metastasis in ccRCC. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5468387 Fri, 02 Dec 2011 05:00:00 +0100 5468387 http://www.medworm.com/index.php?rid=5456974&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F155 Conclusion: Repeated resections after initial metastasectomy can be carried out safely and provide long-term survival in selected patients with recurrent metastasis from RCC. The findings from our case indicate that close follow-up for the early detection of recurrence and complete resection of metastases can improve the results after repeated resection. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5456974 Mon, 28 Nov 2011 05:00:00 +0100 5456974 http://www.medworm.com/index.php?rid=5456973&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F156 Conclusion: The case is an interesting report on a somehow indolent metastatic spread of HCC after LT. It should be considered that metachronous metastatic resectable disease, with no data of recurrence at the primary site in an operable patient, is an indication to perform a surgical resection. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5456973 Mon, 28 Nov 2011 05:00:00 +0100 5456973 http://www.medworm.com/index.php?rid=5440327&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F154 Colorectal cancer (CRC) is the third most common cancer in the word. Liver metastasis is the most common site of colorectal metastases. The prognosis of resectable colorectal liver metastases (CRLM) was improved in the recent years with the consideration of chemotherapy and surgical resection as part of the multidisciplinary management of the disease; the current 5-year survival rates after resection of liver metastases are 25% to 40%. Resectable synchronous or metachronous liver metastases should be treated with perioperative chemotherapy based on three months of FOLFOX4 (5-fluorouracil [5FU], folinic acid [LV], and oxaliplatin) chemotherapy before surgery and three months after surgery. In the case of primary surgery, pseudo-adjuvant chemotherapy for 6 months, based on 5FU/LV, FOLFOX4, X... World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5440327 Thu, 24 Nov 2011 05:00:00 +0100 5440327 http://www.medworm.com/index.php?rid=5440329&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F152 Conclusions: Our multimodal imaging and detection approach to 18F-FDG-directed surgery for known/suspected malignancies is technically and logistically feasible and may allow for real-time intraoperative staging, surgical planning and execution, and determination of completeness of surgical resection. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5440329 Wed, 23 Nov 2011 05:00:00 +0100 5440329 http://www.medworm.com/index.php?rid=5440328&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F153 Conclusion: Preoperative distinction between benign and malignant IPMNs is difficult. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5440328 Wed, 23 Nov 2011 05:00:00 +0100 5440328 http://www.medworm.com/index.php?rid=5421580&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F150 Primary spinal melanomas are extremely rare lesions. In 1906, Hirschberg reported the first primary spinal melanoma, and since then only 40 new cases have been reported. A 47-year-old man was admitted suffering from low back pain, fatigue and loss of body weight persisting for three months. He had a 17-year-old history of an operated primary spinal melanoma from T7-T9, which had remained stable for these 17 years. Routine laboratory findings and clinical symptoms aroused suspicion of a metastatic disease. Multislice computed tomography and magnetic resonance imaging revealed stage-IV melanoma with thoracic, abdominal and skeletal metastases without the recurrence of the primary process. Transiliac crest core bone biopsy confirmed the diagnosis of metastatic melanoma. It is important to kno... World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5421580 Thu, 17 Nov 2011 05:00:00 +0100 5421580 http://www.medworm.com/index.php?rid=5407076&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F149 We report our experience of three patients that underwent parathyroid immediate autotransplanation following extensive surgical manipulations of the neck region for oncological reasons. PTH levels were restored to normal by the fourth postoperative week, allowing us to wean the patients off calcium and vitamin D3 supplementation, which was attributed to full autograft function. Parathyroid autotransplantation, immediate or delayed, is a simple and safe technique which should be considered by the surgeon whenever there is a high risk for postoperative hypoparathyroidism following radical operations of the neck for oncological reasons. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5407076 Tue, 15 Nov 2011 05:00:00 +0100 5407076 http://www.medworm.com/index.php?rid=5400060&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F148 Conclusion: Rectal metastasis from gastric cancer is known to be very rare. However, metastatic gastric adenocarcinoma should be considered as a differential diagnosis for patients presenting with a colorectal mass and a past history of gastric cancer. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5400060 Fri, 11 Nov 2011 05:00:00 +0100 5400060 http://www.medworm.com/index.php?rid=5400061&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F147 In anterior resection of rectum, the section level of inferior mesenteric artery is still subject of controversy between the advocates of high and low tie. The low tie is the division and ligation to the branching of the left colic artery and the high tie is the division and ligation at its origin at the aorta. We intend to assess current scientific evidence in literature and to establish the differences comparing technique, anatomy and physiology. The aim of this protocol is to achieve a meta-analysis that tests safety and feasibility of the two procedures with several types of outcome measures. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5400061 Wed, 09 Nov 2011 05:00:00 +0100 5400061 http://www.medworm.com/index.php?rid=5384516&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F144 We report a rare case of recurrent ovarian cancer presenting as a round ligament metastasis. A 44-year-old woman presented with a lower abdominal mass. Computed tomography showed a pelvic mass. Primary surgery was performed. A histopathological examination showed an ovarian serous adenocarcinoma of Stage IIIb. The patient received 6 cycles of paclitaxel and carboplatin. Almost 2 years after the initial operation, the patient noticed a left inguinal mass. Computed tomography showed a left inguinal mass, 18mm in size. An excisional biopsy was performed and the tumor was found to originate in the left round ligament. A histopathological examination showed serous adenocarcinoma and there was no evidence of lymph node tissue. Recurrence of ovarian cancer in the round ligament is extremely rare.... World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5384516 Mon, 07 Nov 2011 05:00:00 +0100 5384516 http://www.medworm.com/index.php?rid=5384515&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F145 Primitive Gastrointestinal Lymphomas (PGIL) are uncommon tumours, although time-trend analyses have demonstrated an increase. The role of surgery in the management of lymphoproliferative diseases has changed over the past 40 years. Nowadays their treatment is centred on systemic treatments as chemo-/radio- therapy. The aim of this systematic review is to evaluate the actual role of surgery in the treatment of PGIL.A systematic review of literature was conducted according to the recommendations of The Cochrane Collaboration. Main outcomes analysed were overall survival (OS) and disease free survival (DFS).There are currently 1 RCT and 4 non-randomised controlled studies comparing surgical versus medical treatment for PGIL. Seven hundred and one patients were analysed, divided into two group... World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5384515 Mon, 07 Nov 2011 05:00:00 +0100 5384515 http://www.medworm.com/index.php?rid=5384514&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F146 This report suggests the benefit of routine evaluation of HER-2 status in recurrent breast cancer with the introduction of HER-2-targeting agents. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5384514 Mon, 07 Nov 2011 05:00:00 +0100 5384514 http://www.medworm.com/index.php?rid=5384517&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F143 Conclusions: Complete resection of challenging retroperitoneal tumors is feasible and can be done safely with important pre- and intraoperative considerations in mind. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5384517 Fri, 04 Nov 2011 04:00:00 +0100 5384517 http://www.medworm.com/index.php?rid=5384518&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F142 This review attempts to outline the alternative measures and interventions used in bloodless surgery in the field of gynecologic oncology and demonstrate their effectiveness. Nowadays, as increasingly more patients are expressing their fears concerning the potential risks accompanying allogenic transfusion of blood products, putting the theory of bloodless surgery into practice seems to gaining greater acceptance. An increasing number of institutions appear to be successfully adopting approaches that minimize blood usage for all patients treated for gynecologic malignancies. Preoperative, intraoperative and postoperative measures are required, such as optimization of red blood cell mass, adequate preoperative plan and invasive hemostatic procedures, assisting anesthetic techniques, individ... World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5384518 Thu, 03 Nov 2011 04:00:00 +0100 5384518 http://www.medworm.com/index.php?rid=5384520&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F140 Conclusion: This is the second case of solitary fibrous tumor of the small intestine mesentery ever reported. It was managed by en bloc resection and close follow up considering the high risk of recurrence. Investigation should be made regarding the use of adjuvant systemic therapy to improve long-term survival for these patients. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5384520 Mon, 31 Oct 2011 04:00:00 +0100 5384520 http://www.medworm.com/index.php?rid=5384519&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F141 The aim of this study was to compare operating time, postoperative outcomes, and surgical complications of total thyroidectomy plus level III-IV and VI dissection between the no-tie technique using the Harmonic Focus and classic suture ligation for hemostasis. Fifty-four patients underwent total thyroidectomy plus level III-IV and VI dissection by classic suture ligation and 51 patients by the Harmonic Focus. There was obvious distinction as to the operating time between the Focus and classic group (102.8 and 150.1 minutes, respectively, P (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5384519 Mon, 31 Oct 2011 04:00:00 +0100 5384519 http://www.medworm.com/index.php?rid=5359942&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F139 Background: AIB1 (amplified in breast cancer I) is a member of the p160 steroid receptor coactivator family. AIB1 is frequently overexpressed in breast cancer and has functions that promote oncogenesis that are independent of estrogen receptor (ER) coactivation. We investigated prognostic significance of AIB1 and relationship between AIB1 and ER, progesterone receptor (PR), androgen receptor (AR), DAX-1, and HER2. Methods: RNA in situ hybridization and immunohistochemical (IHC) staining for AIB1, IHC staining for ER and the progesterone receptor (PR) and IHC staining and silver in situ hybridization (SISH) for HER2 were performed for 185 breast cancer cases. Results: A high level of expression of AIB1 mRNA was observed in 60.0% of tumors. IHC analysis detected AIB1 positivity in 47.3% of t... World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5359942 Sat, 29 Oct 2011 04:00:00 +0100 5359942 http://www.medworm.com/index.php?rid=5359943&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F138 We successfully performed 6 LESS radical nephrectomy via theretroperitoneal approach (RLESS) using the Alexis wound retractor as a single access with conventional laparoscopic instruments. The results demonstrated that our RLESS technique of radical nephrectomy is a safe and feasible procedure for management of localized renal cancer. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5359943 Fri, 28 Oct 2011 04:00:00 +0100 5359943 http://www.medworm.com/index.php?rid=5359944&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F137 CONCLUSION:This case highlights the importance of adequately analyzing the stage of colon cancer and offering appropriate treatment. Equally important is the early involvement of a surgeon in discussing the timing of the treatment for recurrence. Perhaps if the patient had received chemotherapy or earlier resection, he could have been spared the forequarter amputation. The physician must also be aware of the remote possibility of an unusual presentation of metastasis in order to pursue timely work up. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5359944 Wed, 26 Oct 2011 04:00:00 +0100 5359944 http://www.medworm.com/index.php?rid=5346879&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F136 RetractionThe authors have retracted this article] as it contains large portions of text and figures that have been duplicated from another article previously published in the International Journal of Clinical Oncology . Lead author Dr Tazi accepts full responsibly for the duplication and would like to apologise to the co-authors, Editors and readers as well as the authors of the original article. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5346879 Mon, 24 Oct 2011 04:00:00 +0100 5346879 http://www.medworm.com/index.php?rid=5346880&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F135 Conclusions: Cervicofacial and cervicothoracic flaps provide a technically simple, reliable, safe, efficient and cosmetic means to reconstruct defects of the head and neck. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5346880 Sun, 23 Oct 2011 04:00:00 +0100 5346880 http://www.medworm.com/index.php?rid=5335122&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F134 Conclusions: Malignant SFTP still had the potential recurrence. VATS represents the more acceptable choice for the selected patients with SFTP. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5335122 Thu, 20 Oct 2011 04:00:00 +0100 5335122 http://www.medworm.com/index.php?rid=5335123&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F133 Conclusion: Surgical cases of recurrent inflammatory pseudotumor of the lung have been reported only very rarely. We believe that surgery is the best treatment for recurrent inflammatory pseudotumor of the lung when patients are eligible. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5335123 Tue, 18 Oct 2011 04:00:00 +0100 5335123 http://www.medworm.com/index.php?rid=5323644&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F132 We report a 64-year-old asymptomatic lady with an abnormal cervical cytology, who underwent a conization to reveal an ABC with overlying microinvasive SCC. Doubtful resection margins led us to perform radical hysterectomy with lymph node dissection. Subsequent pathological examination showed a true invasive SCC co-existing with ABC, with invasion of the parametrium. Unlike the indolent course of many pure ABC patients, the prognosis of 11 previously reported co-existing invasive SCC with ABC patients appears to depend on the SCC component. Our case reiterates the importance of adequate biopsy with careful interpretation to cover the possibility of a co-existent malignancy. Besides, it presents an argument in favor of radical surgery for the primary treatment of suspicious associated malign... World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5323644 Tue, 18 Oct 2011 00:26:52 +0100 5323644 http://www.medworm.com/index.php?rid=5323645&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F131 Background: In breast cancer, ER/PgR, HER2, and Ki-67 are important biological markers for predicting prognosis and making effective treatment decisions. In addition, changes in markers due to relapse are also clinically experienced; however, the frequency and clinical significance are still not fully understood. Thus, changes in markers and their correlations with prognosis were investigated.Patients and MethodsOut of the patients with relapse from 1997 to March 2011, there were 97 consecutive patients from whom the lesion was resected and evaluated by immunostaining. The biopsy sites were chest wall, lymph node, ipsilateral breast tumor recurrence, lungs, bones, ovaries and brain. The markers sought were ER, PgR, HER2, p53 and Ki-67. Results: The hormone receptor positive rate from the p... World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5323645 Mon, 17 Oct 2011 04:00:00 +0100 5323645 http://www.medworm.com/index.php?rid=5313855&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F129 Conclusion: for scalp defects wider than100 cm^2, the best tool of reconstruction is free flaps. Pedicled distant flaps are reserved if free flaps are not feasible or failed .Split thickness skin grafts are cosmetically inferior and not suitable for recurrent and irradiated tumours and better reserved for patients who cannot tolerate major operations. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5313855 Sat, 15 Oct 2011 00:26:11 +0100 5313855 http://www.medworm.com/index.php?rid=5313856&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F128 This study aimed to describe an unusual case of metachronous isolated inguinal lymph nodes metastasis from sigmoid carcinoma. A 62-year-old man was referred to our department because of an obstructing sigmoid carcinoma. Colonoscopy showed the obstructing lesion at 30 cm from the anal verge and abdominal CT revealed a sigmoid lesion infiltrating the left lateral abdominal wall. The patient underwent a colonic resection extended to the abdominal wall. Histology showed an adenocarcinoma of the colon infiltrating the abdominal wall with iuxtacolic nodal involvement. Thirty three months after surgery abdominal CT and PET scan revealed a metastatic left inguinal lymph node involvement. The metastatic lymph node was found strictly adherent to the left iliac-femoral artery and encompassing the ori... World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5313856 Fri, 14 Oct 2011 04:00:00 +0100 5313856 http://www.medworm.com/index.php?rid=5313857&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F127 We developed a novel coaxial system using a fine guide needle wire (GNW) to safely and easily place the radiofrequency needle under CT-guidance. The GNW consists of a fine needle (diameter, 21-gauge; length, 150mm) and a wire (0.018 inch, 250mm). An exclusive radiofrequency cannula (14-gauge; 160mm) was also used. This system was used for the treatment of six hepatocellular carcinomas in six patients. All lesions were located deeper than 10cm from the needle entry site. This system was useful in performing CT-guided RF ablation for deeply or precariously located liver lesions particularly in patients who are unable to hold their breath. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5313857 Thu, 13 Oct 2011 04:00:00 +0100 5313857 http://www.medworm.com/index.php?rid=5313858&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F126 Conclusion: Small intestinal submucosa is an easy-to-use biomaterial for preventing complications such as postoperative bleeding and urinary fistula in nephron-sparing surgery, especially in cases where tumor excision causes significant renal capsular and/or renal pelvic defects. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5313858 Wed, 12 Oct 2011 04:00:00 +0100 5313858 http://www.medworm.com/index.php?rid=5304071&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F123 Conclusions: Most malignant ovarian germ cell tumors have excellent prognoses with primary treatment, and good reproductive outcomes can be expected. Because primary treatment failure is associated with the residual disease after the salvage surgery, knowledge of the presence or absence of this risk factor may be helpful in risk stratification and individualization of adjuvant therapy in malignant ovarian germ cell tumors. Further large-scale prospective studies to confirm these results should be performed. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5304071 Tue, 11 Oct 2011 04:00:00 +0100 5304071 http://www.medworm.com/index.php?rid=5304070&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F124 Conclusion: Evaluating the immunohistochemical cytokeratin profile and levels of the TTF-1 and GCDFP-15 of the lesion was useful when distinguishing between pulmonary cancer and metastatic pulmonary tumor. In addition, some patients exhibited changes in the biological properties of the metastatic tumor, and delete tumor resection by video-assisted thoracoscopic surgery can be useful for deciding the drug treatment strategy in some cases (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5304070 Tue, 11 Oct 2011 04:00:00 +0100 5304070 http://www.medworm.com/index.php?rid=5304069&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F125 Conclusion: In patients with a left breast mass associated with erythema and edema, the differential diagnosis should include breast lymphoma in addition. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5304069 Tue, 11 Oct 2011 04:00:00 +0100 5304069 http://www.medworm.com/index.php?rid=5304072&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F122 In this letter I propose the name "Proliferative Multifocal Leukoplakia" with the goal of reducing under-diagnosis of this disease, improve the early diagnosis, try to make an early therapy and control, and prevent its malignant transformation. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5304072 Mon, 10 Oct 2011 04:00:00 +0100 5304072 http://www.medworm.com/index.php?rid=5296583&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F121 Conclusions: The present analysis strongly suggests that altered expression of several stem cell related factors may play different roles in RCC. C-MYC may function as an oncogene and OCT4, KLF4, NANOG and SOX2 as tumor suppressors. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5296583 Fri, 07 Oct 2011 04:00:00 +0100 5296583 http://www.medworm.com/index.php?rid=5296585&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F119 Conclusion: FDG PET / CT has preliminary diagnostic capacity of multiple primary tumors; the final diagnosis should be adopted for specimens after tumor-specific markers IHC to obtain. Consequently, effective therapeutic approaches can be designed and conducted. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5296585 Thu, 06 Oct 2011 04:00:00 +0100 5296585 http://www.medworm.com/index.php?rid=5296584&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F120 CorrectionAfter the publication of this work [1], we became aware of the fact that there was date mistakes in the Abstract, Patients and method and Results sections. The correct text is included below.In the 'Methods' section of the Abstract, the first sentence should have read:"The clinical and follow-up data of 124 patients who were referred to our department for SIRT between June 2008 and October 2010 were evaluated retrospectively."In The 'Patients' section of the Patients and Method, the first sentence should have read:"The clinical and follow-up data of 124 patients who were referred to our department for SIRT between June 2008 and October 2010 were evaluated retrospectively."In the 'Patients' section of the Results, the first sentence should have read:"78 patients (49 M; 29 F; mean ... World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5296584 Thu, 06 Oct 2011 04:00:00 +0100 5296584 http://www.medworm.com/index.php?rid=5285146&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F118 We report the case of a 48 years old man who consulted us with a 2-year history of progressive nasal obstruction, occasional epistaxis, facial pain, and watering of the eyes. A diagnosis of olfactory neuroblastoma was established by histopathology and confirmed by immunohistochemistry. On staging, the mass was classified as a Kadish stage C tumor with extensive involvement of the nasal cavities, nasopharynx, paranasal sinuses and orbit. Endoscopic excision of the mass was done. Traditionally the mainstay of treatment in such locally advanced patients is craniofacial resection followed by adjuvant radiotherapy. Our patient was treated with limited surgery and chemoradiation. Patient is free of recurrence at a follow-up of 5 years. This case report demonstrates the potential efficacy of plan... World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5285146 Wed, 05 Oct 2011 04:00:00 +0100 5285146 http://www.medworm.com/index.php?rid=5285148&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F116 Conclusion: When it is difficult to diagnose intracystic carcinoma of the breast by fine needle aspiration, active lumpectomy is necessary. Because extramural invasion and lymph node metastasis have been reported, it is necessary to carefully determine the range of excision and rationally perform lymph node dissection, such as sentinel node biopsy. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5285148 Tue, 04 Oct 2011 04:00:00 +0100 5285148 http://www.medworm.com/index.php?rid=5285147&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F117 Conclusions: Targeting Bcl-xL will be a promising strategy to inhibit the metastatic potential and reverse the radioresistance of human CRC. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5285147 Tue, 04 Oct 2011 04:00:00 +0100 5285147 http://www.medworm.com/index.php?rid=5273214&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F114 Conclusions: In terms of 5-year survival rates, the TNM-7 system is capable of stratifying post-hepatectomy HCC patients into stages I, II, and III but is unable to stratify stage III patients into stages IIIA, IIIB and IIIC. Lack of tumor encapsulation, AST values >68 U/L, blood loss >500 mL, and AFP values >200 ng/mL are independent prognostic factors affecting long-term survival. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5273214 Fri, 30 Sep 2011 04:00:00 +0100 5273214 http://www.medworm.com/index.php?rid=5273215&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F113 We report the case of a 49-year-old woman who presented with upper-gastrointestinal bleeding two years after the diagnosis of SCC of the cervix. At esophagogastroduodenoscopy, there was a stricture in the second part of the duodenum which was biopsied for a suspected neoplastic lesion. Histologic and immunohistochemical examination showed a malignant lesion with characteristics identical to her original tumor in the cervix confirming the duodenal metastases.The clinical presentation of a 'malignant' upper-gastrointestinal bleed due to duodenal metastases from SCC of the cervix is unusual. Awareness of such infrequent patterns of metastases in cervical cancer confirmed by histopathological diagnosis is important for best practice therapeutic decisions in these patients. (Source: World Journ... World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5273215 Thu, 29 Sep 2011 04:00:00 +0100 5273215 http://www.medworm.com/index.php?rid=5260109&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F112 We report here a 44 -year-old Moroccan man with resectable gastric adenocarcinoma with overexpression of human epidermal growth factor receptor 2 (HER2) by immunohistochemistry who was treated with trastuzumab in combination with chemotherapy in perioperative setting. He received 3 cycles of neoadjuvant chemotherapy consisting of trastuzumab, oxaliplatin, and capecitabine. Afterwards, he received total gastrectomy with extended D2 lymphadenectomy without spleno-pancreatectomy. A pathologic complete response was obtained with a combination of trastuzumab and oxaliplatin and capecitabine. He received 3 more cycles of trastuzumab containing regimen postoperatively.We conclude that resectable gastric carcinoma with overexpression of the c-erbB-2 protein should ideally be managed with periopera... World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5260109 Wed, 28 Sep 2011 04:00:00 +0100 5260109 http://www.medworm.com/index.php?rid=5260110&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F111 Conclusion: Using ex vivo hepatic venography, a direct connection to the hepatic vein from HCC in whole liver was revealed in 2 cases without demonstrated histopathological invasion to hepatic vein for the first time in the literature. The finding suggests that there is direct spillage of HCC cells into the systemic circulation via hepatic vein. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5260110 Tue, 27 Sep 2011 04:00:00 +0100 5260110 http://www.medworm.com/index.php?rid=5260111&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F110 Conclusion: The FOLFOX7 neoadjuvant chemotherapy is not associated with increased postoperative morbidity, indicating that the FOLFOX7 neoadjuvant chemotherapy is a safe choice for the treatment of local advanced gastric cancer. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5260111 Mon, 26 Sep 2011 04:00:00 +0100 5260111 http://www.medworm.com/index.php?rid=5250266&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F109 Situs inversus totalis (SIT) is not itself a premalignant condition, however, rare synchronous or metachronous multiple primary malignancies have been reported. Herein we present a case of synchronous transverse and sigmoid colon cancers and a case of metachronous rectosigmoid colon and gastric cancers in patients with SIT.A 66-year-old male with SIT was referred for a two-month history of hematochezia. Synchronous colonic tumors were found on the proximal transverse and sigmoid colon. The patient underwent open total colectomy and was discharged without incident. A 71-year-old female with rectosigmoid colon cancer and SIT underwent laparoscopy-assisted low anterior resection. Fourteen months after the surgery, the patient developed a single hepatic metastasis and underwent hepatic segment... World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5250266 Fri, 23 Sep 2011 04:00:00 +0100 5250266 http://www.medworm.com/index.php?rid=5236767&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F108 This article provides a meta-analysis of the available evidence showing a poor prognosis for patients with positive B and C viral serology undergoing hepatic resection (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5236767 Wed, 21 Sep 2011 04:00:00 +0100 5236767 http://www.medworm.com/index.php?rid=5236769&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F106 Conclusions: LCA is a rare, primary vascular neoplasm of the spleen that might etiologically be associated with immune dysregulation. In addition, it shows a striking association with synchronous or prior malignancies. With about one-third of the reported cases to date being co-existent with malignancies of visceral organs or immune-mediated diseases, this advocates for close follow-ups in all patients diagnosed with LCA. To our knowledge, this report is the first one of LCA associated with previous pulmonary sarcoidosis and hypothesizes a TNF-alpha related pathogenesis of this splenic tumor. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5236769 Mon, 19 Sep 2011 04:00:00 +0100 5236769 http://www.medworm.com/index.php?rid=5236768&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F107 Conclusion: The overall current literature on fish consumption and the risk of bladder cancer suggested no association. Because of the limited number of studies, further well-designed prospective studies are needed to explore the effect of fish on bladder cancer. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5236768 Mon, 19 Sep 2011 04:00:00 +0100 5236768 http://www.medworm.com/index.php?rid=5224710&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F105 We report a case of metachronous splenic metastases from esophageal cancer and multiple splenic abscesses, which developed nine months after apparently curative esophagectomy without adjuvant chemotherapy. The patient underwent splenectomy with lymph node dissection followed by adjuvant chemotherapy, but liver and skin metastases developed, and the patient died 9 months later. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5224710 Fri, 16 Sep 2011 04:00:00 +0100 5224710 http://www.medworm.com/index.php?rid=5224711&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F104 Conclusion: The case report serves to increase awareness and improve the index of diagnosis and treatment of myoepitheliomas. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5224711 Wed, 14 Sep 2011 04:00:00 +0100 5224711 http://www.medworm.com/index.php?rid=5224712&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F103 We present a rare case of hepatoid adenocarcinoma of the gallbladder which invades deeply the liver bed, in a 59- year-old woman. Histologically, most of the mass in the gallbladder was composed of cells with eosinophilic cytoplasm arranged in a trabecular pattern, which resembled hepatocellular carcinoma.The main differential diagnosis was hepatocellular carcinoma with invasion into the gallbladder. The gallbladder origin of the hepatoid adenocarcinoma was verified by the presence of foci of conventional adenocarcinoma, the recognition of high-grade dysplasia in the adjacent epithelium and the absence of cirrhosis. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5224712 Tue, 13 Sep 2011 04:00:00 +0100 5224712 http://www.medworm.com/index.php?rid=5207872&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F102 Conclusion: It cannot be ignored that the elderly population is getting larger. We must investigate the management of elderly patients after PD and prepare further for more experiences of PD. If appropriate surgical management is provided to elderly patients, we suggest that PD will lead to no adverse effects after surgery, and PD can be performed safely in elderly patients. We conclude that age should not be a contraindication to PD. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5207872 Sun, 11 Sep 2011 04:00:00 +0100 5207872 http://www.medworm.com/index.php?rid=5207873&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F101 Conclusion: Withdrawal therapy appears to produce sustained CB in a significant proportion of patients. This applies not only to withdrawal from tamoxifen, but also from other categories of endocrine agents. Withdrawal from endocrine therapy is, therefore, a viable intercalating option between endocrine agents to minimise resistance and provide additional line of therapy. It should be considered as part of the sequencing of endocrine therapy. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5207873 Fri, 09 Sep 2011 04:00:00 +0100 5207873 http://www.medworm.com/index.php?rid=5207874&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F100 We report a rare male case of an osteoclast-like giant cell tumor originating in an indeterminate mucin-producing cystic neoplasm of the pancreas. A 59-year-old Japanese man with diabetes visited our hospital, complaining of fullness in the upper abdomen. A laboratory analysis revealed anemia (Hemoglobin; 9.7g/dl) and elevated C-reactive protein (3.01mg/dl). Carbohydrate antigen 19-9 was 274U/ml and Carcinoembryonic antigen was 29.6ng/ml. A computed tomography scan of the abdomen revealed a 14-cm cystic mass in the upper left quadrant of the abdomen that appeared to originate from the pancreatic tail. The patient underwent distal pancreatectomy/splenectomy/total gastrectomy/cholecystectomy. The mass consisted of a multilocular cystic lesion. Microscopically, the cyst was lined by cubic or ... World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5207874 Thu, 08 Sep 2011 04:00:00 +0100 5207874 http://www.medworm.com/index.php?rid=5183304&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F99 We report a rare case of synchronous duodenal carcinoma, colonic carcinoma and renal oncocytoma successfully treated using a one-stage surgical approach. Potential risk factors for multiple primary malignancies associated with duodenal carcinoma are discussed. This case illustrates several practice points for consideration: 1. Patients presenting with small intestinal carcinomas have a higher than average chance of developing second primary tumors in other organs; this should be taken into consideration during staging and follow-up. 2. For full staging of patients presenting with small bowel tumors, upper and lower gastrointestinal endoscopy and PET scanning should be considered. 3. A one-stage surgical procedure can be used safely and successfully for multiple synchronous primary tumors. ... World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5183304 Wed, 31 Aug 2011 23:00:00 +0100 5183304 http://www.medworm.com/index.php?rid=5160941&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F97 Conclusions: Although a tumor-like IACNS has no established imaging features, a diagnosis of tumor-like IACNS should be suspected when MRI shows inappropriate presentations of a tumor. Greater awareness of this potential manifestation of IACNS may facilitate more prompt diagnosis and treatment. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5160941 Thu, 25 Aug 2011 23:00:00 +0100 5160941 http://www.medworm.com/index.php?rid=5160942&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F96 Malignant fibrous histiocytoma (MFH) is an aggressive spindle cell cancer of soft-tissue sarcoma s type in the elderly, mostly affecting the extremities. Lesions >5cm, positive margins, and local recurrence are significant poor prognostic indicators. The strongest predictor for distant metastasis was tumor size (>5 cm), and for overall survival, presence of local recurrence. Limb-sparing extensive tumor resection is preferred to achieve negative surgical margins. However, in some circumstances, amputation is inevitable. Recent studies demonstrated that adjuvant radiotherapy for microscopically positive surgical margins significantly improved local control and disease-free survival rates. Therefore, effective therapeutic strategies against locally relapsed high grade MFH are required to pre... World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5160942 Tue, 23 Aug 2011 23:00:00 +0100 5160942 http://www.medworm.com/index.php?rid=5160943&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F95 Among anterior mediastinal lesions, thymoma is the most common. Thymomas are tumors of thymic epithelial cell origin that are distinguished by inconsistent histological and biologic behavior. Chest imaging studies typically show a round or lobulated tumor in the anterior mediastinum. Calcifications in thymomas are classically punctuate or amorphous, positioned within the lesion. Chest computed tomography (CT) features suggesting higher risk thymoma consist of tumor heterogeneity, vascular involvement, lobulation, pulmonary nodules, lymphadenopathy, and pleural manifestations. Imaging findings have an imperfect ability to predict stage and prognosis for thymoma patients. Our objective is to highlight the clinical implications of thymoma calcifications on the diagnosis, clinical manifestatio... World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5160943 Mon, 22 Aug 2011 23:00:00 +0100 5160943 http://www.medworm.com/index.php?rid=5160945&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F93 We report two cases of synchronous, one stage multivisceral resections for pNET and associated reconstruction. We highlight the technical issues involved in such extensive resections and demonstrate that one stage multivisceral operations can be achieved safely. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5160945 Sun, 21 Aug 2011 23:00:00 +0100 5160945 http://www.medworm.com/index.php?rid=5160944&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F94 Eccrine porocarcinoma is a rare malignancy of the eccrine sweat gland. It is usually found frequently on the lower extremities, and it affects both sexes equally usually in the sixth to seventh decade. In our case, we present a 42-year-old male patient with a recurring exophytic tumor on the right lower extremity without local extension. The initial tumor was biopsied, excised and diagnosed as an eccrine poroma. The tumor then recurred 6 years later, was re-excised, reconstructed with a soleus muscle flap and diagnosed as an eccrine porocarcinoma. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5160944 Sun, 21 Aug 2011 23:00:00 +0100 5160944 http://www.medworm.com/index.php?rid=5143177&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F92 Conclusions: The use of different techniques for fashioning a GI do not present significant differences when they are performed by expert surgeons, but further evidence is needed with more randomized trials, in order to have more data supporting the clinical observation. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5143177 Wed, 17 Aug 2011 23:00:00 +0100 5143177 http://www.medworm.com/index.php?rid=5131679&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F91 ${item.shortDescription} (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5131679 Mon, 15 Aug 2011 23:00:00 +0100 5131679 http://www.medworm.com/index.php?rid=5131680&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F90 ${item.shortDescription} (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5131680 Sun, 14 Aug 2011 23:00:00 +0100 5131680 http://www.medworm.com/index.php?rid=5119626&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F88 ${item.shortDescription} (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5119626 Thu, 11 Aug 2011 23:00:00 +0100 5119626 http://www.medworm.com/index.php?rid=5119625&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F89 ${item.shortDescription} (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5119625 Thu, 11 Aug 2011 23:00:00 +0100 5119625 http://www.medworm.com/index.php?rid=5119627&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F87 ${item.shortDescription} (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5119627 Wed, 10 Aug 2011 23:00:00 +0100 5119627 http://www.medworm.com/index.php?rid=5096732&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F84 ${item.shortDescription} (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5096732 Tue, 02 Aug 2011 23:00:00 +0100 5096732 http://www.medworm.com/index.php?rid=5096731&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F85 ${item.shortDescription} (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5096731 Tue, 02 Aug 2011 23:00:00 +0100 5096731 http://www.medworm.com/index.php?rid=5087212&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F83 ${item.shortDescription} (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5087212 Sun, 31 Jul 2011 23:00:00 +0100 5087212 http://www.medworm.com/index.php?rid=5096733&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F82 ${item.shortDescription} (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5096733 Wed, 20 Jul 2011 23:00:00 +0100 5096733 http://www.medworm.com/index.php?rid=5052372&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F82 ${item.shortDescription} (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5052372 Wed, 20 Jul 2011 23:00:00 +0100 5052372 http://www.medworm.com/index.php?rid=5052373&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F81 ${item.shortDescription} (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5052373 Tue, 19 Jul 2011 23:00:00 +0100 5052373 http://www.medworm.com/index.php?rid=5052375&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F79 ${item.shortDescription} (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5052375 Mon, 18 Jul 2011 23:00:00 +0100 5052375 http://www.medworm.com/index.php?rid=5052374&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F80 ${item.shortDescription} (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5052374 Mon, 18 Jul 2011 23:00:00 +0100 5052374 http://www.medworm.com/index.php?rid=5038024&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F78 Conclusion: We describe the first robotic-assisted excision of bilateral oral ranulas in current literature. The use of the da Vinci system provides excellent visualization, magnification, and dexterity for transoral surgical management of ranulas with preservation of the lingual nerve and Wharton's duct with good functional outcomes. However, the use of the robotic system for anterior floor of mouth surgery in terms of improved surgical outcomes as compared to traditional transoral surgery, long-term recurrence rates, and cost effectiveness needs further validation. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5038024 Sun, 17 Jul 2011 23:00:00 +0100 5038024 http://www.medworm.com/index.php?rid=5030042&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F75 Conclusion: PET/CT is a complementary imaging method which can be successfully used in both preoperative and posttherapy evaluation of gastric cancer (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5030042 Wed, 13 Jul 2011 23:00:00 +0100 5030042 http://www.medworm.com/index.php?rid=5030041&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F76 Primary leiomyoma of the pleura is extremely rare. A 45-year-old man presented with a complaint of right chest pain. Chest computed tomography demonstrated a solid, round pleural mass in the right anterior chest wall. The mass was completely resected, and histopathological examination revealed a localized primary pleural leiomyoma. The patient was followed and has been disease-free for over 15 months. This is the first report of primary leiomyoma of the pleura in China. A review of the literature on primary leiomyoma of the pleura is presented. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5030041 Wed, 13 Jul 2011 23:00:00 +0100 5030041 http://www.medworm.com/index.php?rid=5030040&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F77 We describe a patient who developed cough and increasing dyspnoea while on treatment for carcinoma of lip. Chest x-ray and computed tomography were consistent with lymphangitis carcinomatosa. Patient succomed to the illness inspite of treatment with chemotherapy. Lymphangitis carcinomatosa occurs with many different primary tumours and can rarely occur in oral cancers. This is the first report from carcinoma of lip. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5030040 Wed, 13 Jul 2011 23:00:00 +0100 5030040 http://www.medworm.com/index.php?rid=5020034&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F72 Conclusion: Higher incidence of cervical carcinoma is expected in renal transplant recipients, so appropriate surveillance is needed to ensure early detection and treatment of cervical carcinoma. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5020034 Tue, 12 Jul 2011 23:00:00 +0100 5020034 http://www.medworm.com/index.php?rid=5020033&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F73 We present a case of metastatic CDC that responded favorably to a multiple tyrosine kinase inhibitor, sunitinib, achieving a partial response in both lung and skeletal metastases. To our knowledge, this is the first report showing therapeutic activity of sunitinib against CDC. Considering these findings, it would be worthwhile prospectively investigating the role of multiple tyrosine kinase inhibitors, particularly sunitinib, in the management of metastatic CDC. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5020033 Tue, 12 Jul 2011 23:00:00 +0100 5020033 http://www.medworm.com/index.php?rid=5020032&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F74 Background: To compare abdominal hysterectomy, the most currently used for treating cancer of the endometrium, to the vaginal hysterectomy in term of survival, morbidity and failure rates. Methods: We retrospectively analyzed 68 cases divided into two sub-groups. A study group of 31 cases received vaginal surgery; a control group of 37 cases was treated with a laparotomy. Mean operative time, median hospital stay, intra- and post-operative complications, DFS and OS time as well as occurrence of local or distant recurrences have been evaluated and reported. Cases included patients with a higher rate of medical morbidities (p= 0.01) than controls. Results: Mean age was 76.2 and 70.4 years in the vaginal (V) group and abdominal (A) group respectively. Mean operative time was longer for the gr... World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5020032 Tue, 12 Jul 2011 23:00:00 +0100 5020032 http://www.medworm.com/index.php?rid=5020035&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F71 We report a patient undergoing preoperative evaluation with CTA finding of Superior Mesenteric Artery (SMA) originating from the celiac artery. This celiac-mesenteric trunk is rare ( (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5020035 Mon, 11 Jul 2011 23:00:00 +0100 5020035 http://www.medworm.com/index.php?rid=5020036&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F70 Actinomyces species has been described as an opportunistic pathogens, particularly in the oral cavity; however, in rare cases these bacteria can cause actinomycosis which is characterized by formation of abscesses in the mouth, lungs, or gastrointestinal tract.Actinomycosis was commonly present in the pre-antibiotic era; however, it has a low prevalence now days. It has been recognized since 150 years ago, but because of its variable clinical presentation and indolent course, its recognition is difficult and patients are often misdiagnosed. We encounter a case of primary hepatic actinomycosis presenting as a metastatic liver tumor. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5020036 Sun, 10 Jul 2011 23:00:00 +0100 5020036 http://www.medworm.com/index.php?rid=5009496&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F69 Conclusions: In our analysis, patients benefited from a combined modality treatment approach and physicians must consider patient age, performance status, and primary tumor histology when recommending specific treatments regimens. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=5009496 Mon, 04 Jul 2011 23:00:00 +0100 5009496 http://www.medworm.com/index.php?rid=4998446&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F68 Conclusion: These lesions showed a definite geographic variation with ameloblastomas being the most common odontogenic tumors and odontomas being relatively rarer lesions in our region. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=4998446 Mon, 04 Jul 2011 23:00:00 +0100 4998446 http://www.medworm.com/index.php?rid=4993516&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F67 Conclusion: Xanthogranuloma presenting as a form of SMT (submucosal tumor) of the stomach is an extremely rare disease, and diagnosing it preoperatively is difficult. Further accumulation and investigation of this entity is necessary. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=4993516 Fri, 01 Jul 2011 23:00:00 +0100 4993516 http://www.medworm.com/index.php?rid=4977318&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F66 We report a case of ectopic thymoma presenting as a giant right intrathoracic tumor that was treated with resection. The patient was a 50-year-old Japanese woman who presented with the chief complaint of chest pain. Detailed examination revealed a solid tumor measuring 15x10x8 cm in diameter, with a clear border. The Imaging findings suggested a solitary fibrous tumor, and surgery was performed. At surgery, the tumor was found to beadherent to the diaphragm, mediastinal pleura, and lower lobe of the lung, although it could be dissected with relative ease and was removed. Pathological diagnosis indicated a type B1 tumor with no capsular invasion according to the World Health Organization classification, and a diagnosis of Masaoka stage I thymoma was made. No continuity with the normal thymu... World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=4977318 Mon, 27 Jun 2011 23:00:00 +0100 4977318 http://www.medworm.com/index.php?rid=4936227&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F65 Conclusion: Ovarian metastasis is an unusual presentation of cutaneous melanoma and the prognosis was dismal. As illustrated by this case report, a differential diagnosis of a metastatic malignant melanoma must be considered. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=4936227 Thu, 16 Jun 2011 23:00:00 +0100 4936227 http://www.medworm.com/index.php?rid=4936228&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F64 Conclusion: We found that the use of Poppen's approach is strongly supported for the successful removal of pineal region meningiomas without serious complications. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=4936228 Tue, 14 Jun 2011 23:00:00 +0100 4936228 http://www.medworm.com/index.php?rid=4936229&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F63 We present a case of necrotizing vasculitis with the testicle as the isolated affected organ. A 25-year-old man, pretreated for epididymo-orchitis, presented with a presumed testicular neoplasm. Radical orchiectomy was performed and diagnosis of necrotizing vasculitis was established. In the absence of any other sign of systemic disease, the diagnosis of isolated necrotizing vasculitis of the testis was confirmed. Two years after the operation, the patient showed no symptoms of systemic disease. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=4936229 Mon, 13 Jun 2011 23:00:00 +0100 4936229 http://www.medworm.com/index.php?rid=4903621&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F62 Conclusions: Cases have been published with familial adenomatous polyposis (FAP) and simultaneous SH. FAP, Gardner syndrome and Li-Fraumeni syndrome, however, had been ruled out in the present case. To the best of our knowledge, this is the first report describing SH associated with Lynch syndrome. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=4903621 Sun, 05 Jun 2011 23:00:00 +0100 4903621 http://www.medworm.com/index.php?rid=4873073&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F61 Conclusion: In female patients presenting with an isolated axillary mass, with a negative breast work up and known prior history of melanoma, the differential diagnosis should include possible metastatic melanoma. Core biopsy will confirm the diagnosis and tailor subsequent management. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=4873073 Thu, 26 May 2011 23:00:00 +0100 4873073 http://www.medworm.com/index.php?rid=4873074&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F60 Gastrointestinal stromal tumors (GISTs) are rare mesenchymal neoplasms of the gastrointestinal tract (1%), and the stomach is the most common location involved. However, the co-existence of gastric adenocarcinoma and GIST is very rare. A case of an 80-year-old male with a simultaneous presentation of a gastric adenocarcinoma and GIST is presented. Various hypotheses have been proposed in order to explain this rare simultaneous development, but a causal relationship is not documented yet.Keywordsgastric adenocarcinoma; gastrointestinal stromal tumor (GIST) (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=4873074 Wed, 25 May 2011 23:00:00 +0100 4873074 http://www.medworm.com/index.php?rid=4853973&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F58 Merkel cell carcinoma (MCC) is a rare cutaneous tumor and cases located in the eyelid have been described, but still its rarity may lead to difficulty in diagnosis and delay in treatment. A 51-year-old female patient that presented with large lesions in the eyelid underwent surgery after the diagnosis of acute chalazion. Following respiratory distress secondary to pulmonary metastasis, the patient's condition deteriorated and was not fit for complete excision treatment. Histopathological investigation of the biopsies, taken from the tumor, revealed that it was undifferentiated small cell carcinoma. Our aim with this paper is to point out that more cases should be reported for more effective diagnosis, histopathological study, clinical investigation, treatment and prognosis of this specific... World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=4853973 Mon, 23 May 2011 23:00:00 +0100 4853973 http://www.medworm.com/index.php?rid=4853972&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F59 Objective To measure clusterin expression in pancreatic cancer tissues and cell lines and to evaluate whether clusterin confers resistance to gmcitabine in pancreatic cancer cells.Methods Immunohistochemistry for clusterin was performed on 50 primary pancreatic cancer tissues and 25 matched backgrounds, and clusterin expression in 5 pancreatic cancer cell lines was quantified by Western blot and PT-PCR. The correlation between clusterin expression level and gmcitabine IC50 in pancreatic cancer cell lines was evaluated. The effect of an antisense oligonucleotide (ASO) against clusterin(OGX-011) on gmcitabine resistance was evaluated by MTT assays. Xenograft model was used to demonstrate tumor growth.Results Pancreatic cancer tissues expressed significantly higher levels of clusterin than di... World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=4853972 Mon, 23 May 2011 23:00:00 +0100 4853972 http://www.medworm.com/index.php?rid=4853974&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F57 Kaposiform hemangioendothelioma (KHE) is an uncommon vascular tumor of intermediate malignant potential, usually occurs in the extremities and retroperitoneum of infants and is characterized by its association with lymphangiomatosis and Kasabach-Merritt phenomenenon (KMP) in certain cases. It has rarely been observed in the head and neck region and at times, can present without KMP. Herein, we present an extremely uncommon case of KHE occurring in tonsil of a child, associated with a neck swelling, but unassociated with KMP. A 2-year-old male child referred to us with history of sore throat, dyspnoea and right-sided neck swelling off and on, since birth, was clinicoradiologically diagnosed with recurrent tonsillitis, including right sided peritonsillar abscess, for which he underwent right... World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=4853974 Sun, 22 May 2011 23:00:00 +0100 4853974 http://www.medworm.com/index.php?rid=4848420&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F56 Prostate cancer rarely metastasis to the rectum. Findings in the patient reported here emphasize the importance of the relationship between urinary and gastrointestinal symptoms in detecting prostatic neoplasms in older male patients. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=4848420 Fri, 20 May 2011 23:00:00 +0100 4848420 http://www.medworm.com/index.php?rid=4842589&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F54 The Metallothionein (MT) is a protein which has several interesting biological effects and has been demonstrated increase focus on the role of MT in various biological systems in the past three decades. The studies on the role of MT were limited with few areas like apoptosis and antioxidants in selected organs even fifty years after its discovery. Now acknowledge the exploration of various isoforms of MT such as MT-I, MT-II, MT-III and MT-IV and other isoforms in various biological systems.Strong evidence exists that MT modulates complex diseases and the immune system in the body but the primary function of MT still remains unknown. This review's main objective is to explore the capability to specifically manipulate MT levels in cells and in animals to provide answers regarding how MT coul... World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=4842589 Thu, 19 May 2011 23:00:00 +0100 4842589 http://www.medworm.com/index.php?rid=4842588&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F55 Here we report the method of anastomosis based on double stapling technique (hereinafter, DST) using a trans-oral anvil delivery system (EEATM OrVilTM) for reconstructing the esophagus and lifted jejunum following laparoscopic total gastrectomy or proximal gastric resection.As a basic technique, laparoscopic total gastrectomy employed Roux-en-Y reconstruction, laparoscopic proximal gastrectomy employed double tract reconstruction, and end-to-side anastomosis was used for the cut-off stump of the esophagus and lifted jejunum.We used EEATM OrVilTM as a device that permitted mechanical purse-string suture similarly to conventional EEA, and endo-Surgitie.After the gastric lymph node dissection, the esophagus was cut off using an automated stapler. EEATM OrVilTM was orally and slowly inserted f... World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=4842588 Thu, 19 May 2011 23:00:00 +0100 4842588 http://www.medworm.com/index.php?rid=4842590&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F53 Conclusions: The aggressive surgical operation helped to downsize the tumor mass as much as possible, but did not prolonged significantly the life or improved the life quality of the patient. The current literature is reviewed, and the diagnostic approaches as well as therapeutic options are discussed. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=4842590 Wed, 18 May 2011 23:00:00 +0100 4842590 http://www.medworm.com/index.php?rid=4830697&cid=s_31143_6_f&fid=31143&url=http%3A%2F%2Fwww.wjso.com%2Fcontent%2F9%2F1%2F51 Conclusion: The median recurrence free survival of patients in our study was comparable to the reported literature but with significant lost to follow rate. Further large-scale, multi centre studies are needed to have a more comprehensive understanding of this heterogeneous disease in our population. (Source: World Journal of Surgical Oncology) World Journal of Surgical Oncology journals http://www.medworm.com/rss/comments.php?id=4830697 Mon, 16 May 2011 23:00:00 +0100 4830697