MedWorm: ENT & OMF

Temporomandibular joint diagnosis: striking a balance between the sufficiency of clinical assessment and the need for imaging

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Sat, 15 Jun 2013 20:18:27 +0100

An interesting evaluation of the validity of the RDC/TMD for the diagnosis of temporomandibular joint (TMJ) internal derangements and degenerative joint disease (DJD) changes was provided by Galhardo and colleagues. The authors cited the relevant publications from the RDC/TMD Validation Project, and appropriately used the imaging diagnosis criteria by Ahmad et al. One conclusion by Galhardo et al. is that the RDC/TMD is not valid for internal derangement and DJD diagnoses compared to imaging-based criteria. While we agree completely with that point, we wonder what is new in that conclusion. The Validation Project has already shown – convincingly in our view – the limitations of the original RDC/TMD clinical criteria for hard and soft tissue joint diagnosis. Furthermore, the revised c...

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The importance of complementary exams for the diagnosis of temporomandibular joint disorders

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Sat, 15 Jun 2013 20:18:27 +0100

First of all, it was a great honor to have our work mentioned by Prof. Charles Greene and Prof. Richard Ohrbach given the relevance of their names in the field of temporomandibular disorders (TMD) and, especially, in connection with the development of Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD), the only available tool for research on TMD. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Sat, 15 Jun 2013 20:18:27 +0100

(Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)

Editorial Board

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Sat, 15 Jun 2013 20:18:27 +0100

(Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)

Information for Readers

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Sat, 15 Jun 2013 20:18:27 +0100

(Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)

Lymphangioma-like Kaposi sarcoma of the oral mucosa

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Sat, 15 Jun 2013 20:18:26 +0100

We report a series of intra-oral cases of LLKS and review the literature regarding this lesion. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)

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Clinical Pathologic Conference Case 1: Lesion Presenting as a Hemorrhagic Mass of the Alveolar Ridge

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Sat, 15 Jun 2013 20:18:26 +0100

A 64-year-old man presented with a sessile, erythematous, hemorrhagic, lobulated, and ulcerated exophytic mass on the edentulous right maxillary ridge measuring 4.5 × 3 × 2 cm (). The patient reported a 2-year history. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)

Clinical Pathologic Conference Case 2: A Diffuse Swelling Affecting Soft Palate and Oropharynx

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Sat, 15 Jun 2013 20:18:26 +0100

A 47-year-old woman presented with a 2-year history of odynophagia. Her medical, family, and social history were unremarkable. Dental history included full-mouth extractions because of extensive periodontal disease several years earlier. Head and neck extraoral physical examination was also unremarkable, with no evidence of asymmetry, trismus, or cervical lymphadenopathy. Routine panoramic radiographic examination failed to detect any osseous abnormalities. The intraoral examination revealed a 5 × 5-cm firm, diffuse, nontender submucosal mass in the left inferolateral portion of the soft palate () extending to the oropharynx and causing the displacement of the uvula and the lateral wall of the oropharynx medially (). (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, an...

Clinical Pathologic Conference Case 3: A Challenging Case of an Enlarging Swelling of the Maxilla

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Sat, 15 Jun 2013 20:18:26 +0100

A 32-year-old Nigerian female presented to a local dentist with a 2-month history of an enlarging swelling of the upper left labial sulcus, extending from the central incisor to the canine area. The patient had never attended a dentist before this. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)

Clinical Pathologic Conference Case 4: A 15-Year-Old Boy With Radiographic Changes in the Left Mandible

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Sat, 15 Jun 2013 20:18:26 +0100

A 15-year-old boy who experienced pain on chewing was referred regarding mobility of his mandibular left molar teeth. He was otherwise in good health with no relevant medical history. Radiologic examination of the mandible revealed several dental and bony changes: widening of the left ramus of the mandible with a diffuse increase in bone density, the left body of the mandible was vertically enlarged, the third molar crown was deformed and the root was rudimentary or absent, the roots of the mandibular left second molar tooth were shortened, and the second premolar root apex was also slightly foreshortened (). A 99mTc MDP (methoxydiphosphonate) bone scan showed extensive uptake in the left mandible (). Full blood count was normal. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral...

Correlation between articular eminence steepness measured with cone-beam computed tomography and clinical dysfunction index in patients with temporomandibular joint dysfunction

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Sat, 15 Jun 2013 20:18:26 +0100

Conclusion: Based on the present study, there is no apparent relationship between the articular eminence inclination and the clinical Di in patients with TMD. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)

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Diagnostic efficacy of cone-beam computed tomography for mandibular fractures

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Sat, 15 Jun 2013 20:18:26 +0100

Objective: The aim of the study was to determine the clinical efficacy of maxillofacial cone-beam computed tomography (CBCT) for the diagnosis of suspected mandibular fractures and to evaluate whether findings would lead to a change in treatment.Study design: CBCT imaging was performed for 164 patients with suspected mandibular fractures (231 sites) but equivocal clinical and radiological findings (conventional radiography). Images were interpreted by oral and maxillofacial surgeons and treatment decisions based on pre and postimaging were compared. Linear regression analyses were performed.Results: For 63.2% of sites (n = 146) the suspected diagnosis was confirmed by CBCT (P (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)

Prospects and challenges of rendering tissue density in Hounsfield units for cone beam computed tomography

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Sat, 15 Jun 2013 20:18:26 +0100

Conclusions: Artifacts challenge the accurate conversion of density values into HUs. Care should be taken when interpreting quantitative density measurements obtained with CBCT. With more advanced software and methods, it may be possible to improve the consistency and accuracy of density measurements. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)

Society Page

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Sat, 15 Jun 2013 20:18:22 +0100

(Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)

Antibiotic prophylaxis guidelines for prosthetic joints: much ado about nothing?

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Sat, 15 Jun 2013 20:18:22 +0100

A writing committee representing the American Academy of Orthopaedic Surgeons (AAOS) and the American Dental Association (ADA) worked for over 2 years to produce the new 2012 guidelines “Prevention of Orthopaedic Implant Infection in Patients Undergoing Dental Procedures.” This document is quite different than the 1997 and 2003 guidelines, and from what was expected by clinicians in general. Some explanation is needed to understand what was intended and what was accomplished, and where we might go from here. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)

Sensorial differences according to sex and ages

Oral Diseases — Sat, 15 Jun 2013 20:15:04 +0100

ConclusionHigh sensory detection thresholds were observed in subjects over the 6th decade of life, and women had a more accurate sensory perception than men.This article is protected by copyright. All rights reserved. (Source: Oral Diseases)

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Dose‐dependent effect of mitomycin C on human vocal fold fibroblasts

Head and Neck — Fri, 14 Jun 2013 04:00:00 +0100

ConclusionA total of 0.2 mg/mL mitomycin C may provide initial and transient stimulation of collagen for necessary repair to damaged tissue without the long‐term risk of fibrosis. Head Neck, 2013 (Source: Head and Neck)

Gross examination by the surgeon as an alternative to frozen section for assessment of adequacy of surgical margin in head and neck squamous cell carcinoma

Head and Neck — Fri, 14 Jun 2013 04:00:00 +0100

Predictors and timing of recovery in patients with immediate facial nerve dysfunction after parotidectomy

Head and Neck — Fri, 14 Jun 2013 04:00:00 +0100

ConclusionImmediate postparotidectomy facial nerve dysfunction greater than H–B grade III was a significant predictor of permanent dysfunction. Only 2% of patients achieved any improvement beyond 6 months postoperatively. Head Neck, 2013 (Source: Head and Neck)

Oncologic outcomes of transoral laser microsurgery for radiorecurrent laryngeal carcinoma: A systematic review and meta‐analysis of English‐language literature

Head and Neck — Fri, 14 Jun 2013 04:00:00 +0100

ConclusionTLM is oncologically sound in the salvage setting with high larynx‐preservation rate, but there is a trend toward inferior local control rates compared to open partial laryngectomy techniques. © 2013 Wiley Periodicals, Inc. Head Neck, 2013 (Source: Head and Neck)

Preservation of greater auricular nerve during parotidectomy: Sensation, quality of life, and morbidity issues. A Systematic Review

Head and Neck — Fri, 14 Jun 2013 04:00:00 +0100

ConclusionsThere is level Ib evidence that preservation of the greater auricular nerve minimizes the postoperative sensory disturbance and should be considered whenever tumor clearance is not compromised. There is no evidence that overall quality of life is affected when the greater auricular nerve is sacrificed. Head Neck, 2013 (Source: Head and Neck)

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Lymph node density — Prognostic value in head and neck cancer

Head and Neck — Fri, 14 Jun 2013 04:00:00 +0100

ConclusionOur data suggest that lymph node density predicts for OS in patients with head and neck cancer and that the difference in OS may be because of differences in time to failure. © 2013 Wiley Periodicals, Inc. Head Neck, 2013 (Source: Head and Neck)

Predictors of postoperative complications and survival in patients with major salivary glands malignancies: A study highlighting the influence of age

Head and Neck — Fri, 14 Jun 2013 04:00:00 +0100

ConclusionBased on this retrospective analysis reviewing surgically treated patients, age alone should not be a reason to treat elderly patients differently, as it was not a predictor of either complications or disease‐specific survival. © 2013 Wiley Periodicals, Inc. Head Neck, 2013 (Source: Head and Neck)

Salivary duct carcinoma responding to trastuzumab‐based therapy: Case report and review of the literature

Head and Neck — Fri, 14 Jun 2013 04:00:00 +0100

Histologic grade as prognostic indicator for mucoepidermoid carcinoma: A population‐level analysis of 2400 patients

Head and Neck — Fri, 14 Jun 2013 04:00:00 +0100

ConclusionGrade influences the prognosis and distribution of nodal metastases. Results indicate that management guidelines should vary based on grade. © 2013 Wiley Periodicals, Inc. Head Neck, 2013 (Source: Head and Neck)

Circulating CD4‐positive lymphocyte levels as predictor of response to induction chemotherapy in patients with advanced laryngeal cancer

Head and Neck — Fri, 14 Jun 2013 04:00:00 +0100

Conclusion. These findings demonstrate the potential importance of the immune system in chemotherapy response and clinical outcome. Differences in findings between patients with advanced laryngeal and oropharyngeal cancer may reflect different cellular immunity function in the patients with human papillomavirus (HPV)‐16+ oropharyngeal cancer. © 2013 Wiley Periodicals, Inc. Head Neck, 2013 (Source: Head and Neck)

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Combined transoral robotic tongue base surgery and palate surgery in obstructive sleep apnea‐hypopnea syndrome: Expansion sphincter pharyngoplasty versus uvulopalatopharyngoplasty

Head and Neck — Fri, 14 Jun 2013 04:00:00 +0100

ConclusionAs the palate component of our multilevel procedure, expansion sphincter pharyngoplasty, including conventional nose surgery and robotic surgery, seems to be superior to uvulopalatopharyngoplasty. © 2013 Wiley Periodicals, Inc. Head Neck, 2013 (Source: Head and Neck)

Basaloid squamous cell carcinoma of the larynx: Analysis of 145 cases with comparison to conventional squamous cell carcinoma

Head and Neck — Fri, 14 Jun 2013 04:00:00 +0100

ConclusionAnalysis of the largest laryngeal BSCC series to date (n = 145) demonstrates that BSCC carries a worse prognosis than conventional SCC of the larynx. © 2013 Wiley Periodicals, Inc. Head Neck, 2013 (Source: Head and Neck)

Incurable recurrences in patients with oropharyngeal and hypopharyngeal carcinomas

Head and Neck — Fri, 14 Jun 2013 04:00:00 +0100

ConclusionThe knowledge about the courses of disease and especially the remaining lifetime after diagnosed incurability could facilitate the planning of the remaining lifetime in order to achieve the best possible quality of life. © 2013 Wiley Periodicals, Inc. Head Neck, 2013 (Source: Head and Neck)

A child with severe stridor

Emergency Medicine Journal — Thu, 13 Jun 2013 04:00:00 +0100

A 4-year-old boy presented to the emergency department with 1 week's fever and sore throat, associated with progression of respiratory distress since 3 days. He had significant stridor, nasal flaring and marked suprasternal recessions. Parents denied history of foreign body ingestion. Dyspnoea and stridor exacerbated on lying supine and was partially relieved by sit-up position. Physical examination revealed enlarged and exudative tonsils and bilateral cervical lymphadenopathy with tenderness. Neck x-ray, followed by CT, were performed (figures 1 and 2). Subsequent laboratory exams revealed positive heterophile antibodies (Monospot test) and EBV serology. Infectious mononucleosis (IM), mainly resulting from Epstein-Barr virus infection, usually has a benign, self-limited course. ...

EACMFS Prizes & Awards

Journal of Cranio-Maxillofacial Surgery — Tue, 11 Jun 2013 08:17:47 +0100

(Source: Journal of Cranio-Maxillofacial Surgery)

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Announcements

Journal of Cranio-Maxillofacial Surgery — Tue, 11 Jun 2013 08:17:47 +0100

(Source: Journal of Cranio-Maxillofacial Surgery)

Editorial Board

Journal of Cranio-Maxillofacial Surgery — Tue, 11 Jun 2013 08:17:44 +0100

(Source: Journal of Cranio-Maxillofacial Surgery)

Blindness caused by septic superior ophthalmic vein thrombosis in a Lemierre Syndrome variant

Auris, Nasus, Larynx — Tue, 11 Jun 2013 08:17:36 +0100

Abstract: A 65-year-old man presented with right facial cellulitis and right blindness. Enhanced CT and MRI showed right facial cellulitis involved with pterigopalatine fossa. Additionally, orbital cellulitis, superior ophthalmic vein thrombosis, and pulmonary multiple nodules were observed. 18F-FDG PET/CT supported these findings. He was diagnosed with septic superior ophthalmic vein thrombosis accompanied with Lemierre Syndrome variant and was treated mainly by the administration of intravenous antibiotics. His symptoms and image findings improved after a few days of treatment, but the right visual loss has not recovered. Since septic superior ophthalmic vein thrombosis and Lemierre Syndrome both have life-threatening potential, early diagnosis and appropriate treatment are important and...

Intracochlear schwannoma extending to vestibule

Auris, Nasus, Larynx — Tue, 11 Jun 2013 08:17:36 +0100

We report a case of intravestibulocochlear schwannoma causing vertigo that developed from an intracochlear tumor during MRI. We successfully removed the tumor via the transotic approach. (Source: Auris, Nasus, Larynx)

Buccal fat augmentation for insufficient neoglottal closure after supracricoid laryngectomy with cricohyoidoepiglottopexy

Auris, Nasus, Larynx — Tue, 11 Jun 2013 08:17:36 +0100

Conclusions: Buccal fat augmentation to correct insufficient neoglottal closure after SCL-CHEP was technically feasible. A navigation system was helpful for confirmation. Fat absorption occurred and one third of the volume remained at 3 and 6 months. Although, vocal measurements remained unchanged, psychological parameters for voice and swallowing improved. (Source: Auris, Nasus, Larynx)

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Paraganglioma of the maxillary sinus

Auris, Nasus, Larynx — Tue, 11 Jun 2013 08:17:36 +0100

Abstract: Primary paragangliomas of the paranasal sinuses are very rare conditions with only few cases described in the literature. Paragangliomas are locally aggressive, often recur and can metastasize. Usually, open surgery is used to resect such tumors from the sinonasal tract. Here, a case of a large paraganglioma of the left maxillary sinus and nasal cavity, which was successfully removed using the Onyx® embolic agent two days prior to minimally invasive image guided endoscopic sinus surgery, is reported. This case demonstrates that large vascular tumors of the sinonasal tract can be successfully managed by endoscopic endonasal sinus surgery. The patient has no evidence of recurrence after 12 months of follow-up. (Source: Auris, Nasus, Larynx)

Cochlear implantation in a patient with osteogenesis imperfecta

Auris, Nasus, Larynx — Tue, 11 Jun 2013 08:17:36 +0100

Abstract: Osteogenesis imperfecta (OI) is a connective tissue disorder characterized by a deficit in the synthesis of type I collagen. Hearing loss affects 42–58% of OI patients and progresses to deafness in 35–60% of these patients. For OI patients, cochlear implantation (CI) is the only promising treatment option. However, literature on CI in patients with OI is relatively rare. After CI, speech perception is generally good. However, among patients with severe demineralization of the cochlea, most patients are reported to have complications of facial nerve stimulation (FNS), preventing some patients from using the cochlear implant on a daily basis. Here we report a successful CI using a Nucleus CI24 Contour Advance cochlear implant in a patient with OI. Although high-resolution compu...

Warthin's tumor associated with IgG4-related disease

Auris, Nasus, Larynx — Tue, 11 Jun 2013 08:17:36 +0100

Abstract: Immunoglobulin G4-related disease (IgG4-RD) is an inflammatory condition associated with elevated serum IgG4 levels and tissue infiltration by IgG4-expressing plasma cells. Several inflammatory conditions associated with IgG4-RD have been reported. Warthin's tumor is a benign parotid gland tumor consisting of oncocytic epithelial cells and lymphoid stroma containing lymphoid follicles with reactive germinal centers. This is the first report describing a case of Warthin's tumor with possible involvement of IgG4-RD. The patient was a 71-year-old man presenting with swollen right parotid and bilateral submandibular glands. He had a history of a Warthin's tumor of the left parotid gland, autoimmune pancreatitis, and an inflammatory abdominal aortic aneurysm. Laboratory tests revealed...

Tinnitus related to eyelid blinking

Auris, Nasus, Larynx — Tue, 11 Jun 2013 08:17:36 +0100

We present a case of bilateral tinnitus concomitant with eyelid blinking. Otoscopy revealed normal tympanic membranes; however, inward movement of the tympanic membrane was visible whenever the patient blinked. Long-time-based tympanometry measuring static compliance revealed a cogwheel or saw-toothed pattern associated with movement of the tympanic membrane related to eyelid blinking. The patient was managed with pharmacological treatment combined with assurance and was relatively well controlled. (Source: Auris, Nasus, Larynx)

Increased exhaled nitric oxide and its oxidation metabolism in eosinophilic chronic rhinosinusitis

Auris, Nasus, Larynx — Tue, 11 Jun 2013 08:17:35 +0100

Conclusion: A combination of oral and nasal FeNO measurement is a valid marker for the classification and definition of different CRS subtypes in Japan. Higher levels of oral and nasal FeNO in ECRS patients may reflect the persistence of eosinophilic inflammation in sinus mucosa with concomitant iNOS upregulation and accompanying deposition of oxidized NO metabolites. (Source: Auris, Nasus, Larynx)

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Risk factors for olfactory dysfunction in chronic rhinosinusitis

Auris, Nasus, Larynx — Tue, 11 Jun 2013 08:17:35 +0100

Conclusions: Olfactory dysfunction was more severe and prevalent in ECRS than in NECRS. Physician should pay attention to these clinical findings to diagnose olfactory dysfunction, especially in ECRS, and should provide appropriate explanation, guidance, and care. In addition, smokers should be advised to stop smoking to help prevent olfactory dysfunction. (Source: Auris, Nasus, Larynx)

Long term outcome of psychogenic voice disorders

Auris, Nasus, Larynx — Tue, 11 Jun 2013 08:17:35 +0100

Conclusion: Psychogenic voice disorders are often misdiagnosed, leading to inadequate therapy. Psychotherapy (often in combination with voice therapy) was most effective also in the long term, but is often not accepted by patients. Voice therapy alone had a poor success rate. (Source: Auris, Nasus, Larynx)

Synovial sarcomas of the head and neck: Comparative analysis with synovial sarcoma of the extremities

Auris, Nasus, Larynx — Tue, 11 Jun 2013 08:17:35 +0100

Conclusion: The most prevalent location was the PPS. Surgical resection with clear margins correlated with low recurrence. Head and neck sarcomas had similar survival rates compared to sarcomas of limbs. (Source: Auris, Nasus, Larynx)

SOX2 overexpression correlates with poor prognosis in laryngeal squamous cell carcinoma

Auris, Nasus, Larynx — Tue, 11 Jun 2013 08:17:35 +0100

Abstract: Objective: The aim of present study was to investigate the expression of SOX2, a key transcription factor, in LSCC and to assess its prognostic significance.Methods: SOX2 expression of 161 LSCC tissues was detected by immunohistochemistry using a tissue microarray and statistically analyzed for its correlation with clinicopathological charateristics and patient outcome. In addition, SOX2 expression was also observed in 20 self-paired fresh LSCC tissues by western blot.Results: SOX2 was overexpressed in LSCC tissues as compared to the corresponding adjacent normal tissues. SOX2 expression was significantly associated with tumour T classification (p (Source: Auris, Nasus, Larynx)

Bilateral submandibular duct rerouting: Assessment of results on drooling in cerebral palsy cases

Auris, Nasus, Larynx — Tue, 11 Jun 2013 08:17:35 +0100

Conclusion: Considering that during both the first and second follow-up visit only two cases (12.5%) did not respond to treatment, it could be concluded that BSMDR surgery is an effective treatment for reducing drooling in CP children. (Source: Auris, Nasus, Larynx)

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Closure of minor tracheoesophageal fistulae with calcium hydroxlapatite

Auris, Nasus, Larynx — Tue, 11 Jun 2013 08:17:35 +0100

Conclusion: We feel this is an acceptable minimally invasive method to close a persistent pinhole tracheoesophageal fistula after failed management with chemical cautery. (Source: Auris, Nasus, Larynx)

Long-term results of endolymphatic sac drainage with local steroids for intractable Meniere's disease

Auris, Nasus, Larynx — Tue, 11 Jun 2013 08:17:34 +0100

Conclusions: Endolymphatic sac drainage with intra-endolymphatic sac application of large doses of steroids could improve long-term follow-up results of hearing as well as vertigo control. This means that the drainage with local steroids could also improve patients’ long-term quality in the prime of life. (Source: Auris, Nasus, Larynx)

Prognostic factors of synkinesis after Bell's palsy and Ramsay Hunt syndrome

Auris, Nasus, Larynx — Tue, 11 Jun 2013 08:17:34 +0100

Conclusion: It is possible to predict synkinesis following Bell's palsy and Ramsay Hunt syndrome on the basis of clinical symptoms. The lowest Yanagihara score, and the change in Yanagihara score after 1 month, together with the ENoG value at the onset, were found to be especially important factors for predicting synkinesis following Bell's palsy and Ramsay Hunt syndrome. (Source: Auris, Nasus, Larynx)

Long term speech perception after cochlear implant in pediatric patients with GJB2 mutations

Auris, Nasus, Larynx — Tue, 11 Jun 2013 08:17:34 +0100

Conclusion: The long-term results of this study show that CI is also effective in the development of speech performance after CI in Japanese children with GJB2-related hearing impairments as HL due to other etiologies. (Source: Auris, Nasus, Larynx)

Benefit of a new hearing device utilizing cartilage conduction

Auris, Nasus, Larynx — Tue, 11 Jun 2013 08:17:34 +0100

Conclusion: The results of the audiometric tests and interview suggest that the CC hearing aid has potential as a useful amplification device for hearing disability. Unfortunately, if the soft tissue pathway is not involved, the current device is insufficient for the patients with severe hearing loss. The improvement of the output level will lead to develop a reliable CC hearing aid as an alternative to BC hearing aids or bone anchored hearing aids. (Source: Auris, Nasus, Larynx)

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Intranasal phototherapy versus azelastine in the treatment of seasonal allergic rhinitis

Auris, Nasus, Larynx — Tue, 11 Jun 2013 08:17:34 +0100

Conclusion: Whether intranasal phototheraphy will be a standard treatment of SAR or not should be appraised in future studies and clinical trials. (Source: Auris, Nasus, Larynx)

Olfactory changes after endoscopic sinus surgery in patients with chronic rhinosinusitis

Auris, Nasus, Larynx — Tue, 11 Jun 2013 08:17:34 +0100

Conclusion: Olfactory disorders due to ECRS showed transient improvement that deteriorated as time passed after surgery. The olfaction in the non-ECRS patients recovered comparatively well. Postoperative olfactory results were unfavorable in patients without a preoperative reaction to prosultiamine. (Source: Auris, Nasus, Larynx)

Editorial Board

Auris, Nasus, Larynx — Tue, 11 Jun 2013 08:17:33 +0100

(Source: Auris, Nasus, Larynx)

Personalized Medicine: Predicting the risk of complications of cancer therapy

Oral Diseases — Tue, 11 Jun 2013 04:00:00 +0100

Peripheral compound odontoma erupting in the gingiva

Head and Face Medicine — Tue, 11 Jun 2013 04:00:00 +0100

Conclusion: The lesion was surgically removed, and the specimens were analyzed histopathologically. The diagnosis of compound odontoma was established.Clinical significance: This is the twelfth reported case of peripheral odontoma in the gingiva and the first one that erupted in the oral cavity. (Source: Head and Face Medicine)

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Demographic trends and disease‐specific survival in acinic cell carcinoma: An analysis of 1,129 cases

The Laryngoscope — Tue, 11 Jun 2013 04:00:00 +0100

Conclusion: Trends in incidence of AciCC are influenced by gender, race and age. Long‐term survival of this rare malignant tumor is influenced by gender, grade, race, and extent of disease. Future studies need to be conducted to investigate these dynamic trends related to AciCC. (Source: The Laryngoscope)

Prospective clinical trial of gelatin‐thrombin matrix as first line treatment of posterior epistaxis

The Laryngoscope — Tue, 11 Jun 2013 04:00:00 +0100

Conclusion: This pilot study demonstrated that gelatin‐thrombin matrix is a safe and both a clinically effective and cost saving means of treating posterior epistaxis. In this study, its use is associated with a low level of discomfort. This treatment method may improve the quality of care for patients with posterior epistaxis. (Source: The Laryngoscope)

Modalities of treatment for laryngotracheal stenosis: The EVMS experience

The Laryngoscope — Tue, 11 Jun 2013 04:00:00 +0100

Conclusions: Laser incision and/or balloon dilation, are most effective in treatment of pure glottic, subglottic and tracheal stenosis. ultilevel tracheal stenosis warrant closer follow up, and are more likely to require multiple procedures. Worsening stenosis despite endoscopic management warrants an open procedure. Diabetes is associated with an earlier recurrence of stenosis. (Source: The Laryngoscope)

Extra‐esophageal reflux (EER), NOSE score, and sleep quality in a adult clinic population

The Laryngoscope — Tue, 11 Jun 2013 04:00:00 +0100

ConclusionsInsomnia, hypersomnia, and sleep QOL are associated with measures of EER, nasal symptoms, and mood but not OSA risk supporting that disrupted sleep may be a associated with EER and nasal symptoms independent of sleep apnea. (Source: The Laryngoscope)

Merkel cell carcinoma of the head and neck (HNMCC): Potential histopathologic predictors

The Laryngoscope — Tue, 11 Jun 2013 04:00:00 +0100

Conclusion: Adjuvant radiotherapy cannot remediate a positive resection margin. Given these results consideration for revision surgery should be considered for a positive deep margin. Frozen section analysis may help to define the margins in this invasive and aggressive disease. (Source: The Laryngoscope)

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Vocal fold hemorrhage: Factors predicting recurrence

The Laryngoscope — Tue, 11 Jun 2013 04:00:00 +0100

Conclusion: Vocal fold hemorrhage recurred in approximately 25% of patients. Varix was a predictor of recurrence. Monitoring, behavioral mamanagement and/or surgical intervention may be indicated to treat patients with such characteristics. (Source: The Laryngoscope)

Mucoepidermoid carcinoma of the parotid gland treated by surgery and postoperative radiation therapy: Clinicopathologic correlates of outcome

The Laryngoscope — Tue, 11 Jun 2013 04:00:00 +0100

Conclusion: Patients with high‐grade tumors and T4 disease are at increased risk for treatment failure after surgery and postoperative radiation therapy for mucoepidermoid carcinoma of the parotid gland. Investigative strategies to improve outcome should be considered for these particular patients in the future. (Source: The Laryngoscope)

Delayed mobilization after microsurgical reconstruction: An independent risk factor for pneumonia

The Laryngoscope — Tue, 11 Jun 2013 04:00:00 +0100

ConclusionLate mobilization of free flap patients is an independent risk factor for developing post‐operative pneumonia. Earlier mobilization does not increase flap failure rates, is safe, and should be strongly considered in all free flap patients to reduce pulmonary complications. (Source: The Laryngoscope)

Comparison of nasal sprays and irrigations in the delivery of topical agents to the olfactory mucosa

The Laryngoscope — Tue, 11 Jun 2013 04:00:00 +0100

Conclusions: Compared to sprays, irrigations provide a more effective method of delivering topical agents to the posterior and superior aspects of the nasal cavity. The thorough distribution of irrigations has important clinical implications for improving the delivery of therapeutic agents to the olfactory mucosa. (Source: The Laryngoscope)

Replacement of fractured reconstruction plate with customised mandible implant: A novel technique

The Laryngoscope — Tue, 11 Jun 2013 04:00:00 +0100

(Source: The Laryngoscope)

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Obesity is associated with sensorineural hearing loss in adolescents

The Laryngoscope — Tue, 11 Jun 2013 04:00:00 +0100

Conclusions: We demonstrate, for the first time, that obesity in childhood is associated with higher hearing thresholds across all frequencies and an almost 2 fold increase in the odds of unilateral low frequency hearing loss. These results add to the growing literature on obesity related health disturbances and add to the urgency in instituting public health measures to reduce it. (Source: The Laryngoscope)

Trends of human papillomavirus–related head and neck cancers in Korea: National cancer registry data

The Laryngoscope — Tue, 11 Jun 2013 04:00:00 +0100

Conclusions: Although the cultural and ethnic background differs from the United States, cancers of HPV‐related sites are increasing in Korea, whereas cancers of HPV‐unrelated sites are decreasing, which is similar to the trends observed in the United States. Greater public awareness in Korea of HPV‐related HNCs is therefore warranted. (Source: The Laryngoscope)

Cochlear pharmacokinetics of cisplatin ‐ an in vivo study in the guinea pig

The Laryngoscope — Tue, 11 Jun 2013 04:00:00 +0100

Conclusion: The pharmacokinetic findings of an early high concentration of cisplatin in the base of the cochlea and delayed elimination of cisplatin from scala tympani perilymph compared to blood might correlate to the cisplatin‐induced loss of outer hair cells in the base of the cochlea. (Source: The Laryngoscope)

Helmet modification for soft‐band bone‐anchored hearing aid use during cranial orthosis

The Laryngoscope — Tue, 11 Jun 2013 04:00:00 +0100

(Source: The Laryngoscope)

Transsphenoidal approach with nasoseptal flap pedicle transposition: Modified rescue flap technique

The Laryngoscope — Tue, 11 Jun 2013 04:00:00 +0100

(Source: The Laryngoscope)

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Long‐term results of surgical treatment of vocal fold nodules

The Laryngoscope — Tue, 11 Jun 2013 04:00:00 +0100

Conclusions:Postoperative voice therapy decreases the risk of recurrence. Vocal fold nodules can recur over a period of 5 years, consequently requiring follow‐up for at least 5 years in clinical practice and in future prospective studies. Level of Evidence2b (Individual retrospective cohort study). Laryngoscope, 2013 (Source: The Laryngoscope)

What is in this issue

Clinical Otolaryngology — Mon, 10 Jun 2013 04:00:00 +0100

(Source: Clinical Otolaryngology)

Acknowledgements to Reviewers

Clinical Otolaryngology — Mon, 10 Jun 2013 04:00:00 +0100

(Source: Clinical Otolaryngology)

Efficacy of Mitomycin C for postoperative endoscopic sinus surgery: a systematic review and meta‐analysis

Clinical Otolaryngology — Mon, 10 Jun 2013 04:00:00 +0100

ConclusionApplying Mitomycin C topically after endoscopic sinus surgery could reduce the risk of nasal synechiae and maxillary sinus ostium stenosis in short term by 66% and 74%, respectively. The treatment effects may be more beneficial in patients aged 40 years or younger or in patients without history of revision. However, our results were based on pooling trials with questionable methodological quality. Further trials with good research methodology and long‐term follow‐up should be conducted to confirm our results. (Source: Clinical Otolaryngology)

Prospective evaluation of reliability of cone‐beam computed tomography in detecting different position of vibroplasty middle ear implants

Clinical Otolaryngology — Mon, 10 Jun 2013 04:00:00 +0100

ConclusionCone‐beam CT as a radiological control for Vibrant Soundbridge is safe and adequately sensitive and reliable and is therefore suitable for clinical investigation. The position of the ferromagnetic transducer in the middle ear and the presence or absence of an additional coupler could be determined in this study. Therefore, cone‐beam‐CT is useful for the assessment of device failure when there has been gross displacement of the ferromagnetic transducer (or smaller displacements in case of a baseline postoperative cone‐beam CT). Regarding the quality of imaging, cone‐beam CT produced accurate results with different observers with widely varying radiological experience. (Source: Clinical Otolaryngology)

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Anti‐adhesive effect of a thermosensitive poloxamer applied after the removal of nasal packing in endoscopic sinus surgery: a randomised multicentre clinical trial

Clinical Otolaryngology — Mon, 10 Jun 2013 04:00:00 +0100

ConclusionAnti‐adhesive effects of thermosensitive poloxamer are similar to those of Merogel. Therefore, thermosensitive poloxamer can be considered a safe alternative to Merogel for preventing adhesion in patients undergoing endoscopic sinus surgeries, and further evaluation of thermosensitive poloxamer as an anti‐adhesive and primary packing material compared with the control using no packing is needed. (Source: Clinical Otolaryngology)

12‐minute consultation: an evidence‐based approach to the management of dysphagia

Clinical Otolaryngology — Mon, 10 Jun 2013 04:00:00 +0100

ConclusionsA structured history of dysphagia and its associated symptoms, flexible laryngoscopy and endoscopic assessment of swallowing where relevant in addition to targeted investigations should lead to the correct diagnosis and appropriate management. (Source: Clinical Otolaryngology)

Randomized trial comparing intraoral ultrasound to landmark‐based needle aspiration in patients with suspected peritonsillar abscess

Clinical Otolaryngology — Mon, 10 Jun 2013 04:00:00 +0100

(Source: Clinical Otolaryngology)

A randomised trial comparing intraoral ultrasound to landmark‐based needle aspiration in patients with suspected peritonsillar abscess

Clinical Otolaryngology — Mon, 10 Jun 2013 04:00:00 +0100

(Source: Clinical Otolaryngology)

Clinical and prognostic features of lymphomas arising in the head and neck region: Our experience of preferential association of different histotypes with various sites of origin in ninety patients

Clinical Otolaryngology — Mon, 10 Jun 2013 04:00:00 +0100

(Source: Clinical Otolaryngology)

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Multimodality topical therapy for refractory chronic rhinosinusitis: Our experience in thirteen patients with and twelve patients without nasal polyps

Clinical Otolaryngology — Mon, 10 Jun 2013 04:00:00 +0100

(Source: Clinical Otolaryngology)

Sore throat consultations in general practice prior to tonsillectomy among eight hundred and sixty‐three children in England: is this in accordance with the SIGN guidelines?

Clinical Otolaryngology — Mon, 10 Jun 2013 04:00:00 +0100

(Source: Clinical Otolaryngology)

Re: Reducing treatment delay by improving information flow within the multidisciplinary team: a multi cycle audit spiral in head and neck cancer

Clinical Otolaryngology — Mon, 10 Jun 2013 04:00:00 +0100

(Source: Clinical Otolaryngology)

Intra‐operative methylene blue for leak identification during total laryngectomy

Clinical Otolaryngology — Mon, 10 Jun 2013 04:00:00 +0100

(Source: Clinical Otolaryngology)

Pinnaplasty using the three blade scorer

Clinical Otolaryngology — Mon, 10 Jun 2013 04:00:00 +0100

(Source: Clinical Otolaryngology)

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Removing an endosheath

Clinical Otolaryngology — Mon, 10 Jun 2013 04:00:00 +0100

(Source: Clinical Otolaryngology)

Tonsillectomy and residents: a safe match?

Clinical Otolaryngology — Mon, 10 Jun 2013 04:00:00 +0100

(Source: Clinical Otolaryngology)

Earplugs presenting as an impacted foreign body in the ear canal

Clinical Otolaryngology — Mon, 10 Jun 2013 04:00:00 +0100

(Source: Clinical Otolaryngology)

How well is ISCP performing? – an otolaryngologist's overview of the official evaluation report and its executive summary by JCST

Clinical Otolaryngology — Mon, 10 Jun 2013 04:00:00 +0100

(Source: Clinical Otolaryngology)

Erratum

Clinical Otolaryngology — Mon, 10 Jun 2013 04:00:00 +0100

(Source: Clinical Otolaryngology)

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Corrigendum

Clinical Otolaryngology — Mon, 10 Jun 2013 04:00:00 +0100

(Source: Clinical Otolaryngology)

What is the perioperative antibiotic prophylaxis in adult oncologic head and neck surgery?

The Laryngoscope — Mon, 10 Jun 2013 04:00:00 +0100

(Source: The Laryngoscope)

Systemic use of non‐biologic corticosteroids in orofacial diseases

Oral Diseases — Sun, 09 Jun 2013 04:00:00 +0100

This study reviews the corticosteroids in systemic use in management of orofacial mucocutaneous diseases; subsequent studies discuss corticosteroid‐sparing agents used in the management of orofacial diseases, such as calcineurin inhibitors used to produce immunosuppression; purine synthetase inhibitors; and cytotoxic and other immunomodulatory agents. (Source: Oral Diseases)

Notices

The British Journal of Oral and Maxillofacial Surgery — Thu, 06 Jun 2013 20:18:30 +0100

(Source: The British Journal of Oral and Maxillofacial Surgery)

Editorial Board

The British Journal of Oral and Maxillofacial Surgery — Thu, 06 Jun 2013 20:18:28 +0100

(Source: The British Journal of Oral and Maxillofacial Surgery)

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SNP‐based Bayesian networks can predict oral mucositis risk in autologous stem cell transplant recipients

Oral Diseases — Thu, 06 Jun 2013 20:15:08 +0100

ConclusionsOur results suggest that SNP‐based BN developed from saliva‐sourced DNA can predict SOM risk in patients prior to aHSCT.This article is protected by copyright. All rights reserved. (Source: Oral Diseases)

Thyroid Surgery And Voice Outcomes

Health News from Medical News Today — Thu, 06 Jun 2013 07:00:00 +0100

The American Academy of Otolaryngology - Head and Neck Surgery Foundation on Tuesday published a new Clinical Practice Guideline on "Improving Voice Outcomes after Thyroid Surgery" to recognize the importance of the patient's voice and the potential impact thyroid surgery can have on it. "Thyroid surgery rates have tripled over the last three decades," said Sujana S. Chandrasekhar, MD, guideline chair... (Source: Health News from Medical News Today)

37% of child survivors of intrauterine or neonatal insults experience at least one long-term sequela, the most common being neurodevelopmental delay

Evidence-Based Nursing — Thu, 06 Jun 2013 04:00:00 +0100

Commentary on: Mwaniki MK, Atieno M, Lawn JE, et al.. Long-term neurodevelopmental outcomes after intrauterine and neonatal insults: a systematic review. Lancet 2012;379:445–52. Implications for practice and research Neonates who survive major insults in the neonatal period may suffer varying degrees of long-term neurodevelopmental impairment. Most insults might be prevented through primary and secondary measures such as antenatal steroid administration, use of oxygen to reduce the severity of sequelae, maternal immunisation and early detection to prevent/reduce congenital infections. Rehabilitation programmes for survivors should be improved by creating centres to encourage family members to participate in all aspects of care. Context More than 40% of mortality in children younger ...

Microarray Analysis of Two Single-Nucleotide Polymorphisms of Transforming Growth Factor Alpha in Nonsyndromic Cleft Lip and/or Cleft Palate Patients of North China.

The Cleft Palate-Craniofacial Journal — Thu, 06 Jun 2013 04:00:00 +0100

Conclusions: These results support that two SNPs are associated with nonsyndromic CL/P but not for CP in northern Chinese populations. It was demonstrated that this microarray is suitable to test SNPs associated with nonsyndromic CL/P. PMID: 23742131 [PubMed - as supplied by publisher] (Source: The Cleft Palate-Craniofacial Journal)

Can Oral Sex Cause Throat Cancer?

Health News from Medical News Today — Tue, 04 Jun 2013 18:00:00 +0100

Michael Douglas was diagnosed with throat cancer (oropharyngeal cancer) three years ago. He initially said it was caused by years of heavy smoking, alcohol abuse and stress. However, he recently told The Guardian newspaper that it was caused by oral sex (cunnilingus). In an Interview with Guardian reporter, Xan Brooks, Douglas said that his type of cancer was caused by the human papillomavirus (HPV) "which actually comes from cunnilingus"... (Source: Health News from Medical News Today)

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Phospho‐Rb (Ser780) as a biomarker in patients with cervical lymph node metastases from an unknown primary tumour: a retrospective cohort study

Clinical Otolaryngology — Tue, 04 Jun 2013 04:00:00 +0100

ConclusionThe retinoblastoma protein expression of metastatic lymph nodes represents an independent prognostic indicator in patients with cervical metastasis of unknown primary.This article is protected by copyright. All rights reserved. (Source: Clinical Otolaryngology)

Algorithm based on eighteen patients with acquired traumatic earlobe defects not associated with jewellery

Clinical Otolaryngology — Tue, 04 Jun 2013 04:00:00 +0100

Improved visualisation of blood while wearing KTP laser protective eyewear using digital manipulation of endoscopic images

Clinical Otolaryngology — Tue, 04 Jun 2013 04:00:00 +0100

Healing outcomes of large (>50%) traumatic membrane perforations with inverted edges following no intervention, edge approximation and fibroblast growth factor application; a sequential allocation, three‐armed trial

Clinical Otolaryngology — Tue, 04 Jun 2013 04:00:00 +0100

ConclusionEdge approximation of inverted edges has little benefit in improving the healing outcome of large traumatic tympanic membrane perforations and thus is not an ideal treatment option for large traumatic tympanic membrane perforations. Application of basic fibroblast growth factor materially improves the closure rate of large traumatic tympanic membrane perforations and significantly shortens the closure time.This article is protected by copyright. All rights reserved. (Source: Clinical Otolaryngology)

A modified uvulopalatal flap with lateral pharyngoplasty for treatment in ninety two adults with obstructive sleep apnea syndrome

Clinical Otolaryngology — Tue, 04 Jun 2013 04:00:00 +0100

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Chemoradiotherapy for N2 head and neck squamous cell carcinoma ‐ outcomes without a planned neck dissection in two hundred and seven patients

Clinical Otolaryngology — Tue, 04 Jun 2013 04:00:00 +0100

Tumor location‐dependent skip lateral cervical lymph node metastasis in papillary thyroid cancer

Head and Neck — Tue, 04 Jun 2013 04:00:00 +0100

Conclusions Primary tumors in the upper portion of the thyroid are closely linked to skip metastasis. Careful preoperative evaluation of lateral cervical lymph nodes is suggested when a tumor is in the upper portion. © 2013 Wiley Periodicals, Inc. Head Neck, 2013 (Source: Head and Neck)

New device for single‐stage in‐office secondary tracheo‐esophageal puncture. Animal studies

Head and Neck — Tue, 04 Jun 2013 04:00:00 +0100

Management of orocutaneous fistulas using a vacuum‐assisted closure system

Head and Neck — Tue, 04 Jun 2013 04:00:00 +0100

Assessment of functional outcomes in head and neck cancer patients according to the ICF core sets from the perspective of the multi‐professional team – results of four delphi surveys

Head and Neck — Tue, 04 Jun 2013 04:00:00 +0100

Conclusions Although the ICF‐HNC is being currently implemented by the HNC experts, several areas are not covered regularly. Additionally, validated tools were rarely recommended. © 2013 Wiley Periodicals, Inc. Head Neck, 2013 (Source: Head and Neck)

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Phase I/II clinical study on safety and antivascular effects of paclitaxel encapsulated in cationic liposomes for targeted therapy in advanced head and neck cancer

Head and Neck — Tue, 04 Jun 2013 04:00:00 +0100

ConclusionsInfusions of ET appear to be safe and further phase II and III studies are warranted to prove efficacy in the treatment of HNSCC. © 2013 Wiley Periodicals, Inc. Head Neck, 2013 (Source: Head and Neck)

An endoscope‐assisted frenotomy approach to median upper neck masses: Clinical outcomes and safety (from a phase II clinical trial)

Head and Neck — Tue, 04 Jun 2013 04:00:00 +0100

Conclusions: EFA can be a very effective and safe approach for median upper neck masses, and can also lead to excellent cosmetic and functional results. © 2013 Wiley Periodicals, Inc. Head Neck, 2013 (Source: Head and Neck)

Primary orbital eosinophilic angiocentric fibrosis with intranasal extension

Head and Neck — Tue, 04 Jun 2013 04:00:00 +0100

Conclusion: Physicians involved in the treatment of orbital pathologies should be familiar with this entity, since it may manifest as an intraorbital mass growing primarily or secondly into the orbit. The clinical manifestations of eosinophilic angiocentric fibrosis with orbital involvement often mimic other more common ophthalmological diseases. Biopsies are necessary for diagnosis and treatment planning, although cures are usually of palliative effect. © 2013 Wiley Periodicals, Inc. Head Neck, 2013 (Source: Head and Neck)

Cervical metastases from squamous cell carcinoma of hard palate and maxillary alveolus: A retrospective study of 10 years

Head and Neck — Tue, 04 Jun 2013 04:00:00 +0100

Conclusion SCC of hard palate and maxillary alveolus has nonnegligible incidences of both overall and occult metastasis, which were highly associated with pT classification. We recommend routine, synchronous END for T4 lesions while observation is alternative for T1‐T3 lesions. © 2013 Wiley Periodicals, Inc. Head Neck, 2013 (Source: Head and Neck)

Pretreatment circulating monocyte count associated with poor prognosis in patients with oral cavity head and neck cancer

Head and Neck — Tue, 04 Jun 2013 04:00:00 +0100

Conclusion A higher pretreatment circulating monocyte count can be considered as a useful prognostic marker in patients with oral cavity head and neck cancer. © 2013 Wiley Periodicals, Inc. Head Neck, 2013 (Source: Head and Neck)

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Development and validation of the cough severity index: A severity index for chronic cough related to the upper‐airway

The Laryngoscope — Tue, 04 Jun 2013 04:00:00 +0100

Conclusion:The CSI is a short, simple instrument that can be used in the clinical setting to quantify a patient's symptoms of chronic cough of upper airway origin. It represents a statistically reliable, valid, and clinically relevant instrument that can be used to measure treatment outcomes for chronic cough. Level of Evidence2c. Laryngoscope, 2013 (Source: The Laryngoscope)

Differential cochlear implant outcomes in older adults

The Laryngoscope — Tue, 04 Jun 2013 04:00:00 +0100

Conclusions:Patients over the age of 80 years had lower speech perception scores than other adult CI recipients but did not have higher rates of dizziness or vertigo after surgery. A family history of hearing loss was associated with a trend toward better speech recognition, possibly representing a new prognostic variable. These findings provide important information that will aid clinicians in counseling older CI candidates. Level of Evidence2b. Laryngoscope, 2013 (Source: The Laryngoscope)

Lessons learned from a leader and ultimate mentor: Dr. Loring W. Pratt presented at the triological society combined sections meeting, Scottsdale, Arizona, U.S.A.

The Laryngoscope — Tue, 04 Jun 2013 04:00:00 +0100

(Source: The Laryngoscope)

Short‐term outcomes and cost of care of treatment of head and neck paragangliomas

The Laryngoscope — Tue, 04 Jun 2013 04:00:00 +0100

Conclusions:Endovascular treatment of head and neck paragangliomas is associated with an increase in complications and hospital‐related costs. Although these findings may reflect larger tumor size and comorbidity in patients selected for embolization, these data suggest a need to reexamine the benefits and cost‐effectiveness of embolization in surgical patients. Level of Evidence2c. Laryngoscope, 2013 (Source: The Laryngoscope)

Is speech language pathologist evaluation necessary in the nonoperative treatment of head and neck cancer?

The Laryngoscope — Tue, 04 Jun 2013 04:00:00 +0100

(Source: The Laryngoscope)

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Cholesteatoma in cleft lip and palate: A population‐based follow‐up study of children after ventilation tubes

The Laryngoscope — Tue, 04 Jun 2013 04:00:00 +0100

Conclusions:Children with cleft conditions are at increased risk of developing cholesteatoma compared to other children who had one or two MEVTIs, although the overall rate of cholesteatoma is declining. Level of Evidence2b. Laryngoscope, 2013 (Source: The Laryngoscope)

Is there a “July effect” for head and neck cancer surgery?

The Laryngoscope — Tue, 04 Jun 2013 04:00:00 +0100

Conclusions:These data do not support evidence of a “July effect” or an increase in morbidity or mortality at teaching hospitals providing HNCA surgical care. Level of Evidence2c. Laryngoscope, 2013 (Source: The Laryngoscope)

National trends in thyroid surgery and the effect of volume on short‐term outcomes

The Laryngoscope — Tue, 04 Jun 2013 04:00:00 +0100

ConclusionsThese data reflect changing trends in the surgical management of thyroid disease, with meaningful differences in the type of surgical care provided by high‐volume surgeons. Level of Evidence2c. Laryngoscope, 2012 (Source: The Laryngoscope)

Is surgery necessary for all vocal fold polyps?

The Laryngoscope — Tue, 04 Jun 2013 04:00:00 +0100

(Source: The Laryngoscope)

Lessons learned from a leader and ultimate mentor: Dr. Loring W. Pratt

The Laryngoscope — Tue, 04 Jun 2013 04:00:00 +0100

(Source: The Laryngoscope)

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Seeking A Less Toxic Radiation Treatment For HPV-Positive Oropharynx Cancer

Health News from Medical News Today — Mon, 03 Jun 2013 08:00:00 +0100

Researchers from Fox Chase Cancer Center and other institutions have completed a phase II clinical trial that may help identify those patients with HPV-positive oropharyngeal cancer who do not require the full radiation dose given in a standard regimen of Intensity-Modulated Radiation Therapy (IMRT). Preliminary findings were presented by Shanthi Marur, first author on the study and an oncologist at the Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, at the 49th Annual Meeting of the American Society of Clinical Oncology... (Source: Health News from Medical News Today)

Parasympathetic vasoactive intestinal peptide (VIP): a likely contributor to clozapine‐induced sialorrhoea

Oral Diseases — Mon, 03 Jun 2013 04:00:00 +0100

ConclusionsFrom the current preclinical data, we speculate that VIP of parasympathetic origin, by its synergistic interaction with clozapine, may contribute to the clozapine (muscarinic M1‐receptor)‐induced sialorrhoea in schizophrenics. (Source: Oral Diseases)

Mouse ES cells have a potential to differentiate into odontoblast‐like cells using hanging drop method

Oral Diseases — Mon, 03 Jun 2013 04:00:00 +0100

ConclusionsMouse ES cells cultured by the ‘hanging drop’ method are able to differentiate into cells with odontoblast‐specific physiological functions and cell‐surface integrin protein expression. (Source: Oral Diseases)

Hospital‐acquired conditions in head and neck cancer surgery

The Laryngoscope — Mon, 03 Jun 2013 04:00:00 +0100

ConclusionsHACs are uncommon events in HNCA surgical patients. Because prediction of HACs is poor and the potential for human error crosses demographic, geographic, and structural boundaries, universal innovative measures to reduce the occurrence of HACs are needed. Level of Evidence2c. Laryngoscope, 2013 (Source: The Laryngoscope)

Is systematic identification of all four parathyroid glands necessary during total thyroidectomy?: A prospective study

The Laryngoscope — Mon, 03 Jun 2013 04:00:00 +0100

ConclusionsRoutine identification of all four parathyroid glands is not necessary in thyroidectomy performed using capsular dissection technique. Level of Evidence4. Laryngoscope, 2013 (Source: The Laryngoscope)

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Calendar of Events

International Journal of Oral and Maxillofacial Surgery — Sun, 02 Jun 2013 08:17:11 +0100

(Source: International Journal of Oral and Maxillofacial Surgery)

Editorial Board

International Journal of Oral and Maxillofacial Surgery — Sun, 02 Jun 2013 08:17:10 +0100

(Source: International Journal of Oral and Maxillofacial Surgery)

Association Of Tlr2, Tlr3, Tlr4 And Cd14 Genes Polymorphisms With Oral Cancer Risk And Survival

Oral Diseases — Sun, 02 Jun 2013 08:15:14 +0100

ConclusionsTLR3 rs5743312 polymorphism could be considered as potential predictor of worse overall survival in advanced oral cancer, but not independently of nodal status. Haplotypes in TLR3 gene might be associated with poor prognosis in OSCC patients.This article is protected by copyright. All rights reserved. (Source: Oral Diseases)

Oral granulomatosis‐like lesions in liver‐transplanted pediatric patients

Oral Diseases — Sat, 01 Jun 2013 04:00:00 +0100

ConclusionsThis study described specific oral mucosal lesions in liver‐transplanted children. Such lesions have recently been described as a novel entity. Although young age at transplantation has been associated to its development, the etiology of this condition is uncertain.This article is protected by copyright. All rights reserved. (Source: Oral Diseases)

Editorial Board

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Sat, 01 Jun 2013 04:00:00 +0100

(Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)

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Nanotechnology meets oral cancer: how, why, and when?

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Sat, 01 Jun 2013 04:00:00 +0100

The American Cancer Society estimates there will be 41,380 new cases of oral cavity and pharyngeal cancer diagnosed in the United States in 2013, and 7890 Americans will likely die from this disease. Based on Surveillance, Epidemiology and End Results program (SEER) data, the overall relative 5-year survival rate remains low at 61.5% for the most recent reporting period (2002-2008). The standard of care for the treatment of oral cavity squamous cell carcinoma is principally surgical excision for early stage disease, or a combination of surgery and radiation (possibly with chemotherapy) for advanced stage disease and such therapies can be associated with significant morbidity and mortality. The heterogeneous and constantly evolving mutational landscape of a patient's oral cancer has necessi...

Human histological analysis between an autograft symphysis block and an allograft J block with PRGF in a maxillary anterior ridge augmentation

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Sat, 01 Jun 2013 04:00:00 +0100

An autogenous symphysis block graft and an allogeneic J block graft were obtained and simultaneously grafted into a bilateral maxillary anterior ridge deficiency using platelet rich growth factor (PRGF) as a bioactive modifier. PRGF is a biological system of a complex bioactive proteins (transforming growth factor-B1, platelet-derived growth factor, and insulin-like growth factor). The augmented sites were allowed to heal for 6 months before obtaining core biopsy samples for histologic analysis. The purpose of this case study was to compare the histologic findings of an allograft and autograft block using a bioactive modifier, PRGF. The histologic findings from this study indicated bone remodeling with comparable amounts of viable woven and lamellar bone in each sample obtained. (Source: ...

Avulsive helical rim injury: a novel reconstructive technique and case report

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Sat, 01 Jun 2013 04:00:00 +0100

To reconstruct the helical rim as well as scapha region of the ear secondary to a human bite, as well as provide more defined tip-defining points, rotate the nasal tip, as well as correct a septal deviation. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)

Application of distraction osteogenesis in craniofacial and facial reconstructive surgery

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Sat, 01 Jun 2013 04:00:00 +0100

To evaluate the surgical application of distraction osteogenesis of the facial skeleton versus conventional surgical procedures in treating common craniofacial deformities (i.e., cleft lip and palate, dentofacial anomalies) and also in facial reconstruction of post cancer ablation surgeries. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)

Rare metastatic neuroendocrine tumor presenting as a complaint of poorly fitting denture

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Sat, 01 Jun 2013 04:00:00 +0100

We report a metastatic gastrointestinal carcinoid lesion to the mandible and document histo-cytological features of metastatic carcinoid to localize primary. It is recognized that a neuroendocrine tumor can metastasize to the head and neck, but reports of metastasis to the bony mandible are rare. Less than 2 cases of neuroendocrine tumor metastasis to mandible from foregut have been reported. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)

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Marsupialization as opposed to resection for large keratocystic odontogenic tumor (KOCT): a case report

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Sat, 01 Jun 2013 04:00:00 +0100

To evaluate marsupialization as a treatment option for large KCOT. The World Health Organization has given odontogenic keratocyst a new name based on its behavior, histology, and genetics. Renamed “keratocystic odontogenic tumor” (KCOT) and defined as “benign unicystic or multicystic intraosseous tumor of odontogenic origin with a characteristic lining of parakeratinized stratified squamous epithelium and potential for aggressive infiltrative behavior.” Treatment modalities include marsupialization, enucleation with or without peripheral ostectomy, chemical debridement, and resection. Despite the plethora of literature, treatment of large KCOT remains controversial, with no established consensus. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics...

Papillary squamous cell carcinoma: retrospective analysis of 41 cases

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Sat, 01 Jun 2013 04:00:00 +0100

Squamous cell carcinoma is the most common malignancy of the head and neck, with multiple variants being described in the literature. Papillary squamous cell carcinoma represents a variant that is often underdiagnosed as a benign entity. The purpose of this study is to identify the histopathologic and behavioral characteristics of papillary squamous cell carcinoma, leading to appropriate diagnosis and treatment. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)

Early recognition and prevention of TEN: a cautionary report of 2 cases and literature review

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Sat, 01 Jun 2013 04:00:00 +0100

In this report, 2 cases are described in which the early recognition and cessation of medication therapy could have prevented both patients’ deaths secondary to the development of extensive TEN complicated by Gram-negative sepsis. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)

Myositis ossificans traumatica of the temporalis muscle: case report and review of the literature

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Sat, 01 Jun 2013 04:00:00 +0100

This case report reviews a unique case of myositis ossificans traumatica (MOT), a rare bone-forming process of mesenchymal stem cells within skeletal muscle or periosteum, involving a muscle of mastication. Literature review covers MOT etiology, types of myositis ossificans, differential diagnosis, radiographic and histologic findings, and treatment options. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)

A focused review of local anesthetic admixture with dexmedetomidine in regional anesthesia; what, if any, clinical implications does this have in oral and maxillofacial surgery?

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Sat, 01 Jun 2013 04:00:00 +0100

Dexmedetomidine, a potent a2 adrenoreceptor agonist, being 8 times more selective for the receptor versus clonidine has been shown to produce sedation, analgesia, and sympatholytic effects during intravenous sedation. Its usage has also been shown to be efficacious in prolonging the local anesthetic effect in regional anesthesia, lessening the local anesthetic requirement and prevention in adverse events such as local anesthetic toxicity. Moreover, it has been efficacious in treating pain in patients with cancer and Complex Regional Pain syndrome, as well as in neuropathic pain for which there was prior nerve damage. What, if any, implications could this have for our patient population? (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)

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Bisphosphonates: boon or a bane? a survey

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Sat, 01 Jun 2013 04:00:00 +0100

Bisphosphonates are given to patients with conditions characterized by excessive bone resorption including osteoporosis, osteopenia, Paget’s disease, multiple myeloma, and metastatic bone cancer. As with any drug, it has various side effects ranging from digestive problem to ocular side effects. About 8 years ago, oral and maxillofacial surgeons first identified and reported the link between necrotic bone in the jaws of patients and the use of IV bisphosphonates. Even though the occurrence of BRONJ is rare and almost always associated with IV bisphosphonates, recent publications show an increase in incidence of BRONJ with both oral and IV bisphosphonates. New cases are being reported with oral bisphosphonates associated with and without surgical intervention. As the oral form is the most...

Facial feminization surgery: case report, utilizing computer assisted surgical simulation and a novel technique for cranioplasty

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Sat, 01 Jun 2013 04:00:00 +0100

Facial feminization surgery (FFS) refers to a set of surgical procedures that help to feminize, by facial alteration, a male-to-female transsexual to aid with society's acceptance and recognition of the transsexual as a female. The hard and soft tissue techniques used include scalp advancement, cranioplasty, brow lift, rhinoplasty, malar augmentation, bi-maxillary osteotomy, lip lift, mandibuloplasty, genioplasty, and chondrolaryngoplasty. To date, computer-aided design and computer aided manufacturing (CAD/CAM) and computer assisted surgical stimulation (CASS) technology have been used for reliable surgeries in the middle and lower thirds of the face. The aim of this case study is to review the current facial feminization surgery (FFS) surgical modalities, and propose a technique to provi...

Increasing expression of insulin-like growth factor I in masseter as protective therapy targeting the muscular apoptosis and remodeling physiology of TMD pain

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Sat, 01 Jun 2013 04:00:00 +0100

The temporomandibular joint (TMJ) is a site of chronic pain problems commonly associated with overload in the muscles of mastication and the resulting stress on the joint. A potential therapy can be seen in the ability of insulin-like growth factor I (IGF-1) to enhance repair and maintain tissue health. Faster and increased growth and repair through increased IGF-1 expression in the masseter may promote muscle that is more resistant to the normal increase in apoptosis found in overloaded masseter, potentially reducing symptoms of TMJ pain. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)

Reconstruction of large soft tissue chin defects with a combination of z-plasty and inferior submental advancement flaps

Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics — Sat, 01 Jun 2013 04:00:00 +0100

Autogenous block grafting has long been a modality of treatment to create adequate bone volume in larger osseous deficient ridges prior to dental implant placement. With some autogenous donor sites being unfavorable anatomically to harvest from, clinicians have turned to using allogenic block materials. With the development of allogenic corticocancellous J blocks, it has allowed the clinician to seek other options of grafting when our gold standard, autogenous blocking, is unavailable. (Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics)

MedWorm: ENT & OMF

Temporomandibular joint diagnosis: striking a balance between the sufficiency of clinical assessment and the need for imaging

The importance of complementary exams for the diagnosis of temporomandibular joint disorders

Contents

Editorial Board

Information for Readers

Lymphangioma-like Kaposi sarcoma of the oral mucosa

Clinical Pathologic Conference Case 1: Lesion Presenting as a Hemorrhagic Mass of the Alveolar Ridge

Clinical Pathologic Conference Case 2: A Diffuse Swelling Affecting Soft Palate and Oropharynx

Clinical Pathologic Conference Case 3: A Challenging Case of an Enlarging Swelling of the Maxilla

Clinical Pathologic Conference Case 4: A 15-Year-Old Boy With Radiographic Changes in the Left Mandible

Correlation between articular eminence steepness measured with cone-beam computed tomography and clinical dysfunction index in patients with temporomandibular joint dysfunction

Diagnostic efficacy of cone-beam computed tomography for mandibular fractures

Prospects and challenges of rendering tissue density in Hounsfield units for cone beam computed tomography

Society Page

Antibiotic prophylaxis guidelines for prosthetic joints: much ado about nothing?

Sensorial differences according to sex and ages

Dose‐dependent effect of mitomycin C on human vocal fold fibroblasts

Gross examination by the surgeon as an alternative to frozen section for assessment of adequacy of surgical margin in head and neck squamous cell carcinoma

Predictors and timing of recovery in patients with immediate facial nerve dysfunction after parotidectomy

Oncologic outcomes of transoral laser microsurgery for radiorecurrent laryngeal carcinoma: A systematic review and meta‐analysis of English‐language literature

Preservation of greater auricular nerve during parotidectomy: Sensation, quality of life, and morbidity issues. A Systematic Review

Lymph node density — Prognostic value in head and neck cancer

Predictors of postoperative complications and survival in patients with major salivary glands malignancies: A study highlighting the influence of age

Salivary duct carcinoma responding to trastuzumab‐based therapy: Case report and review of the literature

Histologic grade as prognostic indicator for mucoepidermoid carcinoma: A population‐level analysis of 2400 patients

Circulating CD4‐positive lymphocyte levels as predictor of response to induction chemotherapy in patients with advanced laryngeal cancer

Combined transoral robotic tongue base surgery and palate surgery in obstructive sleep apnea‐hypopnea syndrome: Expansion sphincter pharyngoplasty versus uvulopalatopharyngoplasty

Basaloid squamous cell carcinoma of the larynx: Analysis of 145 cases with comparison to conventional squamous cell carcinoma

Incurable recurrences in patients with oropharyngeal and hypopharyngeal carcinomas

A child with severe stridor

EACMFS Prizes & Awards

Announcements

Editorial Board

Blindness caused by septic superior ophthalmic vein thrombosis in a Lemierre Syndrome variant

Intracochlear schwannoma extending to vestibule

Buccal fat augmentation for insufficient neoglottal closure after supracricoid laryngectomy with cricohyoidoepiglottopexy

Paraganglioma of the maxillary sinus

Cochlear implantation in a patient with osteogenesis imperfecta

Warthin's tumor associated with IgG4-related disease

Tinnitus related to eyelid blinking

Increased exhaled nitric oxide and its oxidation metabolism in eosinophilic chronic rhinosinusitis

Risk factors for olfactory dysfunction in chronic rhinosinusitis

Long term outcome of psychogenic voice disorders

Synovial sarcomas of the head and neck: Comparative analysis with synovial sarcoma of the extremities

SOX2 overexpression correlates with poor prognosis in laryngeal squamous cell carcinoma

Bilateral submandibular duct rerouting: Assessment of results on drooling in cerebral palsy cases

Closure of minor tracheoesophageal fistulae with calcium hydroxlapatite

Long-term results of endolymphatic sac drainage with local steroids for intractable Meniere's disease

Prognostic factors of synkinesis after Bell's palsy and Ramsay Hunt syndrome

Long term speech perception after cochlear implant in pediatric patients with GJB2 mutations

Benefit of a new hearing device utilizing cartilage conduction

Intranasal phototherapy versus azelastine in the treatment of seasonal allergic rhinitis

Olfactory changes after endoscopic sinus surgery in patients with chronic rhinosinusitis

Editorial Board

Personalized Medicine: Predicting the risk of complications of cancer therapy

Peripheral compound odontoma erupting in the gingiva

Demographic trends and disease‐specific survival in acinic cell carcinoma: An analysis of 1,129 cases

Prospective clinical trial of gelatin‐thrombin matrix as first line treatment of posterior epistaxis

Modalities of treatment for laryngotracheal stenosis: The EVMS experience

Extra‐esophageal reflux (EER), NOSE score, and sleep quality in a adult clinic population

Merkel cell carcinoma of the head and neck (HNMCC): Potential histopathologic predictors

Vocal fold hemorrhage: Factors predicting recurrence

Mucoepidermoid carcinoma of the parotid gland treated by surgery and postoperative radiation therapy: Clinicopathologic correlates of outcome

Delayed mobilization after microsurgical reconstruction: An independent risk factor for pneumonia

Comparison of nasal sprays and irrigations in the delivery of topical agents to the olfactory mucosa

Replacement of fractured reconstruction plate with customised mandible implant: A novel technique

Obesity is associated with sensorineural hearing loss in adolescents

Trends of human papillomavirus–related head and neck cancers in Korea: National cancer registry data

Cochlear pharmacokinetics of cisplatin ‐ an in vivo study in the guinea pig

Helmet modification for soft‐band bone‐anchored hearing aid use during cranial orthosis

Transsphenoidal approach with nasoseptal flap pedicle transposition: Modified rescue flap technique

Long‐term results of surgical treatment of vocal fold nodules

What is in this issue

Acknowledgements to Reviewers

Efficacy of Mitomycin C for postoperative endoscopic sinus surgery: a systematic review and meta‐analysis

Prospective evaluation of reliability of cone‐beam computed tomography in detecting different position of vibroplasty middle ear implants

Anti‐adhesive effect of a thermosensitive poloxamer applied after the removal of nasal packing in endoscopic sinus surgery: a randomised multicentre clinical trial

12‐minute consultation: an evidence‐based approach to the management of dysphagia

Randomized trial comparing intraoral ultrasound to landmark‐based needle aspiration in patients with suspected peritonsillar abscess