MedWorm: Geriatrics

Alzheimer's Society comment on Health Select Committee Report

Alzheimers Society — Wed, 08 Feb 2012 21:36:35 +0100

A new report by the Health Select Committee is calling for greater integration of the existing fragmented health and social care services. (Source: Alzheimers Society)

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Stents, Blood Thinners Star at Stroke Meeting (with video)

MedPage Today Geriatrics — Wed, 08 Feb 2012 20:13:05 +0100

NEW ORLEANS (MedPage Today) -- In this International Stroke Conference wrap-up, Larry Goldstein, MD, from Duke University, highlights some of the more exciting and important clinical studies presented here. (Source: MedPage Today Geriatrics)

Pradaxa Worth It in Cases of Prior Stroke (CME/CE)

MedPage Today Geriatrics — Wed, 08 Feb 2012 17:42:17 +0100

NEW ORLEANS (MedPage Today) -- Dabigatran (Pradaxa) is more cost-effective than warfarin at preventing stroke in atrial fibrillation patients who have had a prior stroke or transient ischemic attack, a model analysis showed. (Source: MedPage Today Geriatrics)

Strategy Shift With Age Can Lead To Navigational Difficulties

Health News from Medical News Today — Wed, 08 Feb 2012 08:00:00 +0100

A Wayne State University researcher believes studying people's ability to find their way around may help explain why loss of mental capacity occurs with age. Scott Moffat, Ph.D., associate professor of psychology and gerontology in the College of Liberal Arts and Sciences and Institute of Gerontology at WSU, said studies have demonstrated reliable differences in navigation and spatial learning tasks based on age. Younger adults tend to outperform their elders in spatial navigation, Moffat said, and people seem to start switching navigational strategies with age... (Source: Health News from Medical News Today)

Relationship of health literacy to intentional and unintentional non-adherence of hospital discharge medications

NeLM - Care of Older People — Wed, 08 Feb 2012 05:00:00 +0100

Source: Journal of General Internal Medicine Area: Evidence > Medicines Management > References Background: Inadequate health literacy is prevalent among seniors and is associated with poor health outcomes. At hospital discharge, medications are frequently changed and patients are informed of these changes via their discharge instructions. Objectives: To explore the association between health literacy and medication discrepancies 48 hours after hospital discharge and determine the causes of discharge medication discrepancies. Design: Face-to-face surveys assessing health literacy at hospital discharge using the short form of the Test of Functional Health Literacy in Adults (sTOFHLA). We obtained the medication lists from the written discharge instructions. At...

Smartphone training helps people with memory impairment regain independence

EurekAlert! - Social and Behavioral Science — Wed, 08 Feb 2012 05:00:00 +0100

(Baycrest Centre for Geriatric Care) The treatment for moderate-to-severe memory impairment could one day include a prescription for a smartphone. (Source: EurekAlert! - Social and Behavioral Science)

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BMD Values and GSTM3 Gene Polymorphisms in Combination with GSTT1/GSTM1 Genes: A Genetic Association Study in Slovenian Elderly

Gerontology — Tue, 07 Feb 2012 23:00:00 +0100

Gerontology (DOI:10.1159/000335048) (Source: Gerontology)

Novel Vaccine Protects Against Meningococcus B (CME/CE)

MedPage Today Geriatrics — Tue, 07 Feb 2012 21:10:18 +0100

(MedPage Today) -- An investigational vaccine against meningococcal B disease produced robust immune responses in infants, researchers reported. (Source: MedPage Today Geriatrics)

Making Inroads in Treating RA, a Clinical Context Report (CME/CE, with video)

MedPage Today Geriatrics — Tue, 07 Feb 2012 15:56:55 +0100

(MedPage Today) -- In this exclusive video report, Chaim Putterman, MD, of Albert Einstein College of Medicine in New York City, reviews the progress being made in the treatment of rheumatoid arthritis with MedPage Today staff writer Nancy Walsh. (Source: MedPage Today Geriatrics)

Avoid Window Seats to Cut Risk for In-Flight Blood Clots: Study

The Doctors Lounge - Cardiology — Tue, 07 Feb 2012 15:00:00 +0100

Experts say DVTs can strike any immobilized passenger, not just those in economy class (Source: The Doctors Lounge - Cardiology)

New Analysis Finds No Antidepressant-Suicide Link In Youths

Health News from Medical News Today — Tue, 07 Feb 2012 09:00:00 +0100

In 2004, concerns about antidepressant drugs increasing suicidal thoughts and behaviors in young patients prompted the FDA to issue a rare "black box warning." Now, a new analysis of clinical trial data finds that treatment with the antidepressant fluoxetine did not increase - or decrease - suicidality in children compared to placebo treatment. An analysis built on data from 41 trials and more than 9,000 patients also found that two different popular antidepressant drugs were effective at reducing suicidal behavior and depressive symptoms in adult and geriatric patients... (Source: Health News from Medical News Today)

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School Vending Machines Still Offer Too Many Sugary Snacks

MedicineNet Senior Health General — Tue, 07 Feb 2012 07:00:00 +0100

Title: School Vending Machines Still Offer Too Many Sugary SnacksCategory: Health NewsCreated: 2/7/2012 11:00:00 AMLast Editorial Review: 2/7/2012 (Source: MedicineNet Senior Health General)

Smoking in Men Speeds Up Mental Decline

MedicineNet Senior Health General — Tue, 07 Feb 2012 07:00:00 +0100

Title: Smoking in Men Speeds Up Mental DeclineCategory: Health NewsCreated: 2/7/2012 11:00:00 AMLast Editorial Review: 2/7/2012 (Source: MedicineNet Senior Health General)

Kids Who Feel Left Out Are Less Active

MedicineNet Senior Health General — Tue, 07 Feb 2012 07:00:00 +0100

Title: Kids Who Feel Left Out Are Less ActiveCategory: Health NewsCreated: 2/7/2012 11:00:00 AMLast Editorial Review: 2/7/2012 (Source: MedicineNet Senior Health General)

Even for the Overweight, Exercise Helps the Heart

MedicineNet Senior Health General — Tue, 07 Feb 2012 07:00:00 +0100

Title: Even for the Overweight, Exercise Helps the HeartCategory: Health NewsCreated: 2/7/2012 10:05:00 AMLast Editorial Review: 2/7/2012 (Source: MedicineNet Senior Health General)

Letting Baby Eat Finger Foods May Spur Healthier Weight

MedicineNet Senior Health General — Tue, 07 Feb 2012 07:00:00 +0100

Title: Letting Baby Eat Finger Foods May Spur Healthier WeightCategory: Health NewsCreated: 2/7/2012 10:05:00 AMLast Editorial Review: 2/7/2012 (Source: MedicineNet Senior Health General)

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Metformin Preferred Drug for Type 2 Diabetes, Experts Say

MedicineNet Senior Health General — Tue, 07 Feb 2012 07:00:00 +0100

Title: Metformin Preferred Drug for Type 2 Diabetes, Experts SayCategory: Health NewsCreated: 2/6/2012 6:06:00 PMLast Editorial Review: 2/7/2012 (Source: MedicineNet Senior Health General)

Pancreas May 'Taste' Fructose, Hinting at Links to Diabetes

MedicineNet Senior Health General — Tue, 07 Feb 2012 07:00:00 +0100

Title: Pancreas May 'Taste' Fructose, Hinting at Links to DiabetesCategory: Health NewsCreated: 2/6/2012 6:06:00 PMLast Editorial Review: 2/7/2012 (Source: MedicineNet Senior Health General)

Antidepressants May Not Raise Suicide Risk in Youth: Study

MedicineNet Senior Health General — Tue, 07 Feb 2012 07:00:00 +0100

Title: Antidepressants May Not Raise Suicide Risk in Youth: StudyCategory: Health NewsCreated: 2/6/2012 6:06:00 PMLast Editorial Review: 2/7/2012 (Source: MedicineNet Senior Health General)

Certain Cancer Drugs May Have Fatal Side Effects: Analysis

MedicineNet Senior Health General — Tue, 07 Feb 2012 07:00:00 +0100

Title: Certain Cancer Drugs May Have Fatal Side Effects: AnalysisCategory: Health NewsCreated: 2/6/2012 6:06:00 PMLast Editorial Review: 2/7/2012 (Source: MedicineNet Senior Health General)

Spanking Produces Troubled Kids, Study Contends

MedicineNet Senior Health General — Tue, 07 Feb 2012 07:00:00 +0100

Title: Spanking Produces Troubled Kids, Study ContendsCategory: Health NewsCreated: 2/6/2012 2:06:00 PMLast Editorial Review: 2/7/2012 (Source: MedicineNet Senior Health General)

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Health Highlights: Feb. 6, 2012

MedicineNet Senior Health General — Tue, 07 Feb 2012 07:00:00 +0100

Title: Health Highlights: Feb. 6, 2012Category: Health NewsCreated: 2/6/2012 2:05:00 PMLast Editorial Review: 2/7/2012 (Source: MedicineNet Senior Health General)

Insomnia

MedicineNet Senior Health General — Tue, 07 Feb 2012 07:00:00 +0100

Title: InsomniaCategory: Diseases and ConditionsCreated: 6/6/2005Last Editorial Review: 2/7/2012 (Source: MedicineNet Senior Health General)

Smoking in Men Speeds Up Mental Decline

MedicineNet Alzheimer — Tue, 07 Feb 2012 07:00:00 +0100

Title: Smoking in Men Speeds Up Mental DeclineCategory: Health NewsCreated: 2/7/2012 11:00:00 AMLast Editorial Review: 2/7/2012 (Source: MedicineNet Alzheimer)

Insomnia

MedicineNet Alzheimer — Tue, 07 Feb 2012 07:00:00 +0100

Title: InsomniaCategory: Diseases and ConditionsCreated: 6/6/2005Last Editorial Review: 2/7/2012 (Source: MedicineNet Alzheimer)

Drug burden index and Beers criteria: impact on functional outcomes in older people living in self-care retirement villages

NeLM - Care of Older People — Tue, 07 Feb 2012 05:00:00 +0100

The objectives of this study were to determine whether Drug Burden Index (DBI), a measure of individuals' exposure to anticholinergic and sedative drugs, and Beers criteria, an explicit measure of potentially inappropriate drug use, are associated with function in older adults living in low-level care facilities; and to compare DBI with Beers criteria as a predictor of function in older people. The study population consisted of 115 residents living in low-level care facilities in Sydney, Australia. Data on demographics, drugs, and comorbidities were collected. Outcomes included objective measures of physical function Short Performance Physical Battery (SPPB) and grip strength. In total, 50 (44%) participants were exposed to DBI drugs, 51 (44%) participants received at least...

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Heart Failure, Osteoporosis Go ‘Hand-in-Hand’: Researchers

The Doctors Lounge - Cardiology — Tue, 07 Feb 2012 05:00:00 +0100

Cardiac condition raises the risks of falls and may contribute to bone-density loss (Source: The Doctors Lounge - Cardiology)

Risk of Death From Certain Breast Cancers May Rise With Age

The Doctors Lounge - Oncology — Tue, 07 Feb 2012 05:00:00 +0100

Research focused on estrogen-sensitive tumors; undertreatment might play a role, expert says (Source: The Doctors Lounge - Oncology)

Antidepressants May Not Raise Suicide Risk in Youth: Study

The Doctors Lounge - Psychiatry — Mon, 06 Feb 2012 22:00:00 +0100

Despite 'black box warning' for drugs such as Prozac, no increase -- or decrease -- was found (Source: The Doctors Lounge - Psychiatry)

Am J Geriatr Psychiatry; +17 new citations

Am J Geriatr Psychia... — Mon, 06 Feb 2012 15:06:02 +0100

17 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: Am J Geriatr Psychiatry These pubmed results were generated on 2012/02/06PubMed, a service of the National Library of Medicine, includes over 15 million citations for biomedical articles back to the 1950's. These citations are from MEDLINE and additional life science journals. PubMed includes links to many sites providing full text articles and other related resources. (Source: Am J Geriatr Psychia...)

Geriatric Patients At High Risk Of Vitamin D Deficiency

Health News from Medical News Today — Mon, 06 Feb 2012 09:00:00 +0100

The great majority of geriatric patients in a German rehabilitation hospital were found to have vitamin D deficiency. Stefan Schilling presents his study results in Deutsches Arzteblatt International (Dtsch Arztebl Int 2012; 109[3]: 33-8). In order to establish the vitamin D status in geriatric patients in Germany, the researchers measured 25-OH vitamin D in 1578 patients in the geriatric rehabilitation hospital in Trier after they had been examined on admission. Insufficiently high concentrations were found in 89% of patients, and 67% had severe vitamin D deficiency... (Source: Health News from Medical News Today)

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Health Highlights: Feb. 3, 2012

MedicineNet Alzheimer — Mon, 06 Feb 2012 07:00:00 +0100

Title: Health Highlights: Feb. 3, 2012Category: Health NewsCreated: 2/3/2012 2:05:00 PMLast Editorial Review: 2/6/2012 (Source: MedicineNet Alzheimer)

The Impact of Dementia Severity on Caregiver Burden in Frontotemporal Dementia and Alzheimer Disease

Alzheimer Disease and Associated Disorders — Mon, 06 Feb 2012 06:00:00 +0100

This study is the first to show that caregivers of SemDem, PNFA, and AD patients show similar burden, while confirming that bvFTD caregivers show higher burden than AD caregivers. More importantly, this study demonstrates that burden worsens with disease progression in FTD. (C) 2012 Lippincott Williams & Wilkins, Inc. (Source: Alzheimer Disease and Associated Disorders)

Are Seniors Enjoying Sex More Than the Rest of Us?

Psychology Today Relationships Center — Mon, 06 Feb 2012 05:35:32 +0100

Sexually active Americans aged 57-85 are having sex as often as those aged 18-59. But here is the surprise (or not so surprising) finding. Those enjoying sex are happier with their lives and their marriage regardless of health status and financial situation. read more (Source: Psychology Today Relationships Center)

Impact of Smoking on Cognitive Decline in Early Old Age: The Whitehall II Cohort Study [Original Article]

Archives of General Psychiatry — Mon, 06 Feb 2012 05:00:00 +0100

Conclusions Compared with never smokers, middle-aged male smokers experienced faster cognitive decline in global cognition and executive function. In ex-smokers with at least a 10-year cessation, there were no adverse effects on cognitive decline. (Source: Archives of General Psychiatry)

Suicidal Thoughts and Behavior With Antidepressant Treatment: Reanalysis of the Randomized Placebo-Controlled Studies of Fluoxetine and Venlafaxine [Meta-analysis]

Archives of General Psychiatry — Mon, 06 Feb 2012 05:00:00 +0100

Conclusions Fluoxetine and venlafaxine decreased suicidal thoughts and behavior for adult and geriatric patients. This protective effect is mediated by decreases in depressive symptoms with treatment. For youths, no significant effects of treatment on suicidal thoughts and behavior were found, although depression responded to treatment. No evidence of increased suicide risk was observed in youths receiving active medication. To our knowledge, this is the first research synthesis of suicidal thoughts and behavior in depressed patients treated with antidepressants that examined the mediating role of depressive symptoms using complete longitudinal person-level data from a large set of published and unpublished studies. (Source: Archives of General Psychiatry)

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Front & Back Matter

Dementia and Geriatric Cognitive Disorders — Sun, 05 Feb 2012 23:00:00 +0100

Dement Geriatr Cogn Disord 2011;32:X (DOI:10.1159/000337015) (Source: Dementia and Geriatric Cognitive Disorders)

Distinguishing Between The Forgetful And Those At Risk Of Alzheimer's Disease

Health News from Medical News Today — Sun, 05 Feb 2012 08:00:00 +0100

It can be difficult to distinguish between people with normal age-associated memory loss and those with amnestic mild cognitive impairment (aMCI). However people with aMCI are at a greater risk of developing Alzheimer's disease (AD), and identification of these people would mean that they could begin treatment as early as possible. New research published in BioMed Central's open access journal BMC Geriatrics shows that specific questions, included as part of a questionnaire designed to help diagnose AD, are also able to discriminate between normal memory loss and aMCI... (Source: Health News from Medical News Today)

Winter Can Pose Hazards for Seniors

The Doctors Lounge - Health News — Sat, 04 Feb 2012 15:00:00 +0100

For those with mobility problems, snow and ice can leave them stranded at home (Source: The Doctors Lounge - Health News)

Association between multi-dose drug dispensing and drug treatment changes

European Journal of Clinical Pharmacology — Fri, 03 Feb 2012 17:51:13 +0100

Conclusions MDD is associated with fewer changes in drug treatment compared with OP. Further studies of risks and benefits from this prescribing procedure are urged. Content Type Journal ArticleCategory Pharmacoepidemiology and PrescriptionPages 1-7DOI 10.1007/s00228-012-1230-9Authors Christina Sjöberg, Department of Geriatrics, Sahlgrenska University Hospital/Mölndal, 431 80 Mölndal, SwedenHenrik Ohlsson, Centre for Primary Health Care Research, Lund University/Region Skåne, Skåne University Hospital, Malmö, SwedenSusanna M Wallerstedt, Department of Clinical Pharmacology, Sahlgrenska University Hospital, 413 45 Gothenburg, Sweden Journal European Journal of Clinical PharmacologyOnline ISSN 1432-1041Print ISSN 0031-6970 (Source: European Journal of Clin...

Erratum to: Ethnic differences in composite indices of femoral neck strength

Osteoporosis International — Fri, 03 Feb 2012 17:11:21 +0100

Content Type Journal ArticleCategory ErratumPages 1-2DOI 10.1007/s00198-011-1887-4Authors S. Ishii, Geriatric Research, Education and Clinical Center (GRECC), VA Greater Los Angeles Healthcare System, 11301 Wilshire Blvd, Building 220, Room 302, Los Angeles, CA 90073, USAJ. A. Cauley, Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 130 DeSoto Street, A524 Crabtree, Pittsburgh, PA 15260, USAG. A. Greendale, Department of Medicine/Division of Geriatrics, David Geffen School of Medicine at UCLA, 10933 Le Conte Ave, Los Angeles, CA 90095, USAM. E. Danielson, Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, 130 DeSoto Street, A524 Crabtree, Pittsburgh, PA 15260, USAN. Safaei Nili, Department of Medicine/Division ...

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Questionnaire Could Help Predict Alzheimer’s: Study

The Doctors Lounge - Psychiatry — Fri, 03 Feb 2012 15:00:00 +0100

21 simple questions may help docs determine which patients need more testing, researchers say (Source: The Doctors Lounge - Psychiatry)

Enhancing Care for Hospitalized Older Adults with Cognitive Impairment: A Randomized Controlled Trial

Journal of General Internal Medicine — Fri, 03 Feb 2012 07:20:49 +0100

Conclusion A simple screening program for CI followed by a CDSS did not change physician prescribing behaviors or improve the process of care for hospitalized older adults with CI. Content Type Journal ArticleCategory Original ResearchPages 1-7DOI 10.1007/s11606-012-1994-8Authors Malaz A. Boustani, Indiana University Center for Aging Research, Indianapolis, IN, USANoll L. Campbell, Indiana University Center for Aging Research, Indianapolis, IN, USABabar A. Khan, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USAGreg Abernathy, Regenstrief Institute, Inc, 410 West 10th Street, Suite 2000, Indianapolis, IN 46202, USAMohammed Zawahiri, Indiana University Center for Aging Research, Indianapolis, IN, USATiffany Campbell, Indiana Universit...

Norovirus Causes Most Hospital Infection Outbreaks

MedicineNet Senior Health General — Fri, 03 Feb 2012 07:00:00 +0100

Title: Norovirus Causes Most Hospital Infection OutbreaksCategory: Health NewsCreated: 2/3/2012 11:01:00 AMLast Editorial Review: 2/3/2012 (Source: MedicineNet Senior Health General)

Itch Intensity and Scratching Pleasure Vary at Different Body Sites

MedicineNet Senior Health General — Fri, 03 Feb 2012 07:00:00 +0100

Title: Itch Intensity and Scratching Pleasure Vary at Different Body SitesCategory: Health NewsCreated: 2/3/2012 11:01:00 AMLast Editorial Review: 2/3/2012 (Source: MedicineNet Senior Health General)

1 in 2 Stroke Survivors Has High Blood Pressure

MedicineNet Senior Health General — Fri, 03 Feb 2012 07:00:00 +0100

Title: 1 in 2 Stroke Survivors Has High Blood PressureCategory: Health NewsCreated: 2/3/2012 11:01:00 AMLast Editorial Review: 2/3/2012 (Source: MedicineNet Senior Health General)

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New Heart Failure Risks: Fractures and Memory Problems

MedicineNet Senior Health General — Fri, 03 Feb 2012 07:00:00 +0100

Title: New Heart Failure Risks: Fractures and Memory ProblemsCategory: Health NewsCreated: 2/3/2012 11:01:00 AMLast Editorial Review: 2/3/2012 (Source: MedicineNet Senior Health General)

Sex and the Elderly: STD Risk Often Ignored

MedicineNet Senior Health General — Fri, 03 Feb 2012 07:00:00 +0100

Title: Sex and the Elderly: STD Risk Often IgnoredCategory: Health NewsCreated: 2/3/2012 11:00:00 AMLast Editorial Review: 2/3/2012 (Source: MedicineNet Senior Health General)

Could a Blood Test Help Spot Depression?

MedicineNet Senior Health General — Fri, 03 Feb 2012 07:00:00 +0100

Title: Could a Blood Test Help Spot Depression?Category: Health NewsCreated: 2/3/2012 10:05:00 AMLast Editorial Review: 2/3/2012 (Source: MedicineNet Senior Health General)

Some Stroke Survivors Can't Recognize Fear, Anger in Others

MedicineNet Senior Health General — Fri, 03 Feb 2012 07:00:00 +0100

Title: Some Stroke Survivors Can't Recognize Fear, Anger in OthersCategory: Health NewsCreated: 2/2/2012 6:06:00 PMLast Editorial Review: 2/3/2012 (Source: MedicineNet Senior Health General)

Mouse Study Suggests Alzheimer's Spreads Through Brain Like an Infection

MedicineNet Senior Health General — Fri, 03 Feb 2012 07:00:00 +0100

Title: Mouse Study Suggests Alzheimer's Spreads Through Brain Like an InfectionCategory: Health NewsCreated: 2/2/2012 4:06:00 PMLast Editorial Review: 2/3/2012 (Source: MedicineNet Senior Health General)

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Too Few American Adults Getting Needed Vaccinations: CDC

MedicineNet Senior Health General — Fri, 03 Feb 2012 07:00:00 +0100

Title: Too Few American Adults Getting Needed Vaccinations: CDCCategory: Health NewsCreated: 2/2/2012 4:06:00 PMLast Editorial Review: 2/3/2012 (Source: MedicineNet Senior Health General)

Scientists May Be Closer to Developing 'Red Wine' Drug

MedicineNet Senior Health General — Fri, 03 Feb 2012 07:00:00 +0100

Title: Scientists May Be Closer to Developing 'Red Wine' DrugCategory: Health NewsCreated: 2/2/2012 2:06:00 PMLast Editorial Review: 2/3/2012 (Source: MedicineNet Senior Health General)

Anemia May Boost Death Risk After Stroke

MedicineNet Senior Health General — Fri, 03 Feb 2012 07:00:00 +0100

Title: Anemia May Boost Death Risk After StrokeCategory: Health NewsCreated: 2/2/2012 2:06:00 PMLast Editorial Review: 2/3/2012 (Source: MedicineNet Senior Health General)

irbesartan, Avapro

MedicineNet Senior Health General — Fri, 03 Feb 2012 07:00:00 +0100

Title: irbesartan, AvaproCategory: MedicationsCreated: 6/6/1999 10:33:00 PMLast Editorial Review: 2/3/2012 (Source: MedicineNet Senior Health General)

Mouse Study Suggests Alzheimer's Spreads Through Brain Like an Infection

MedicineNet Alzheimer — Fri, 03 Feb 2012 07:00:00 +0100

Title: Mouse Study Suggests Alzheimer's Spreads Through Brain Like an InfectionCategory: Health NewsCreated: 2/2/2012 4:06:00 PMLast Editorial Review: 2/3/2012 (Source: MedicineNet Alzheimer)

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Agitation From Sedation in Elderly

Consultant Live — Fri, 03 Feb 2012 06:30:02 +0100

Geriatric patients can get agitated in response to sedation. How do you respond? (Source: Consultant Live)

[Original Articles] Relationship Between Depressive Symptoms, Anemia, and Iron Status in Older Residents From a National Survey Population

Psychosomatic Medicine — Fri, 03 Feb 2012 05:00:00 +0100

Conclusions Iron deficiency commonly co-occurs with depressive symptoms in older people, although the association with anemia is accounted for by physical health status and may primarily reflect anemia of chronic disease. (Source: Psychosomatic Medicine)

Medication reconciliation during the transition to and from long-term care settings: a systematic review

NeLM - Care of Older People — Fri, 03 Feb 2012 05:00:00 +0100

Source: Research in Social and Administrative Pharmacy Area: Evidence > Medicines Management > References Background: Medication reconciliation has been recognised as an important process in care transitions to prevent adverse health outcomes. Because older adults have multiple comorbid conditions and use multiple medications, they are more likely to experience complicated transitions between acute and long-term care settings. Hence, it is important to develop effective interventions to protect older adults at transition points of care. Objective: To systematically review the literature and evaluate studies performing medication reconciliation interventions in patients transferred to and from long-term care settings. Methods: The literature search focused on studie...

Informant-reported cognitive symptoms that predict amnestic mild cognitive impairment

BMC Geriatrics — Fri, 03 Feb 2012 05:00:00 +0100

Specific questions in an informant-rated questionnaire designed to detect Alzheimers Disease are also able to discriminate between normal memory loss and amnesic mild cognitive impairment, allowing earlier identification of those at higher risk of developing Alzheimers Disease. (Source: BMC Geriatrics)

Vitamin D deficiency in geriatric patients

EurekAlert! - Medicine and Health — Fri, 03 Feb 2012 05:00:00 +0100

(Deutsches Aerzteblatt International) The great majority of geriatric patients in a German rehabilitation hospital were found to have vitamin D deficiency. Stefan Schilling presents his study results in this week's issue of Deutsches Ärzteblatt International. (Source: EurekAlert! - Medicine and Health)

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Alzheimer's hallmark could affect brain function of healthy adults, study claims

Alzheimers Society — Thu, 02 Feb 2012 21:37:42 +0100

High levels of the protein amyloid beta in the brain – a hallmark of Alzheimer's disease - could also be associated with the memory and mental function of healthy adults. (Source: Alzheimers Society)

Semantic memory and language dysfunction in early Alzheimer's disease: a review

International Journal of Geriatric Psychiatry — Thu, 02 Feb 2012 21:34:56 +0100

ConclusionsIdentifying and classifying the nature and degree of language impairment more closely could aid in developing targeted therapies. Treatments already established in other aphasic states, such as post‐stroke, may be especially relevant. The nature of these and the protective nature of cognitive reserve are potential therapeutic avenues. Copyright © 2012 John Wiley & Sons, Ltd. (Source: International Journal of Geriatric Psychiatry)

Clot Busters OK for 'Wake-Up' Strokes (CME/CE, with video)

MedPage Today Geriatrics — Thu, 02 Feb 2012 20:13:04 +0100

NEW ORLEANS (MedPage Today) -- Patients who wake up with stroke symptoms that weren't present when they fell asleep can safely receive thrombolytic treatment with tissue plasminogen activator, a British study suggested. (Source: MedPage Today Geriatrics)

Mouse Study Suggests Alzheimer’s Spreads Through Brain Like an Infection

The Doctors Lounge - Neurology — Thu, 02 Feb 2012 20:00:00 +0100

If validated, finding might open doors to new therapies, even a vaccine, experts say (Source: The Doctors Lounge - Neurology)

Fast Memory Decline Tied to Fatal Stroke (CME/CE)

MedPage Today Geriatrics — Thu, 02 Feb 2012 19:15:38 +0100

(MedPage Today) -- A sharp decline in memory was associated with worse stroke outcomes and could be a marker for cerebrovascular disease, a large study found. (Source: MedPage Today Geriatrics)

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PCI Upgraded in 'Appropriate Use' Updates (CME/CE)

MedPage Today Geriatrics — Thu, 02 Feb 2012 16:37:50 +0100

(MedPage Today) -- Percutaneous coronary intervention is now considered appropriate in relatively benign three-vessel disease, according to an update of criteria for revascularization of complex coronary artery disease. (Source: MedPage Today Geriatrics)

Medicare Pay Policy on Transplant Drugs Slammed

MedPage Today Geriatrics — Thu, 02 Feb 2012 16:32:58 +0100

(MedPage Today) -- Medicare's failure to provide lifelong coverage for immunosuppressive therapy after kidney transplant is bad for patients and for the system's finances, two researchers argued. (Source: MedPage Today Geriatrics)

Same Genes Key to Early & Late-Onset Alzheimer’s: Study

The Doctors Lounge - Neurology — Thu, 02 Feb 2012 15:00:00 +0100

Individual risk factors may influence when the brain disorder develops, researchers say (Source: The Doctors Lounge - Neurology)

Baby Aspirin for Geriatric Patients

Consultant Live — Thu, 02 Feb 2012 12:00:00 +0100

Advice for getting aspirin into older patients (Source: Consultant Live)

Helping Seniors With Pain: New GSA Resources

Health News from Medical News Today — Thu, 02 Feb 2012 09:00:00 +0100

The pain suffered by older adults is the shared focus of the two newest entries in The Gerontological Society of America's (GSA) From Publication to Practice* series. Together they address both pain management and new labeling changes for one of the most popular pain medications, acetaminophen. Both issues aim to provide readers with information on how new advances in pain prevention, treatment, and management may improve care and quality of life for older adults... (Source: Health News from Medical News Today)

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Worrying Too Much Might Raise Your Risk for Stroke

MedicineNet Alzheimer — Thu, 02 Feb 2012 07:00:00 +0100

Title: Worrying Too Much Might Raise Your Risk for StrokeCategory: Health NewsCreated: 2/1/2012 6:06:00 PMLast Editorial Review: 2/2/2012 (Source: MedicineNet Alzheimer)

Stress, Allostatic Load, Catecholamines, and Other Neurotransmitters in Neurodegenerative Diseases.

Cellular and Molecular Neurobiology — Thu, 02 Feb 2012 05:00:00 +0100

Authors: Goldstein DS Abstract As populations age, the prevalence of geriatric neurodegenerative diseases will increase. These diseases generally are multifactorial, arising from complex interactions among genes, environment, concurrent morbidities, treatments, and time. This essay provides a concept for the pathogenesis of Lewy body diseases such as Parkinson disease, by considering them in the context of allostasis and allostatic load. Allostasis reflects active, adaptive processes that maintain apparent steady states, via multiple, interacting effectors regulated by homeostatic comparators-"homeostats." Stress can be defined as a condition or state in which a sensed discrepancy between afferent information and a setpoint for response leads to activation of effectors, reducing th...

How to tell apart the forgetful from those at risk of Alzheimer's disease

EurekAlert! - Social and Behavioral Science — Thu, 02 Feb 2012 05:00:00 +0100

(BioMed Central) It can be difficult to distinguish between people with normal age-associated memory loss and those with amnestic mild cognitive impairment. However people with aMCI are at a greater risk of developing Alzheimer's disease. New research published in BioMed Central's open access journal BMC Geriatrics shows that specific questions, included as part of a questionnaire designed to help diagnose AD, are also able to discriminate between normal memory loss and aMCI. (Source: EurekAlert! - Social and Behavioral Science)

Geriatric Nutritional Risk Index May Be a Significant Predictor of Mortality in Korean Hemodialysis Patients: A Single Center Study

Therapeutic Apheresis and Dialysis — Thu, 02 Feb 2012 05:00:00 +0100

We examined the GNRI of 120 maintenance HD patients and followed these patients for 120 months. Predictors for all‐cause death were examined using life table analysis and the Cox proportional hazards model. Life table analysis revealed that subjects with a GNRI < 90 (n = 19) had a marginally lower survival rate than did those with a GNRI ≥ 90 (n = 101) (Wilcoxon test, P = 0.048). Multivariate Cox proportional hazards analyses demonstrated that the GNRI was a significant predictor of mortality (hazard ratio 0.966, 95% confidence interval 0.945–0.995, P = 0.018), after adjusting for age, sex, presence of diabetes mellitus, and body weight. These results demonstrate that the GNRI may be a significant predictor of mortality in Korean HD patients. (Source: The...

Rational opioid dosing in the elderly: dose and dosing interval when initiating opioid therapy

NeLM - Care of Older People — Thu, 02 Feb 2012 05:00:00 +0100

Source: Clinical Pharmacology and Therapeutics Area: Evidence > Medicines Management > References Opioids are the mainstay of treatment for moderate to severe pain. However, opioid therapy in the elderly is often associated with significant morbidity because of excessive ventilatory depression. The large amount of interindividual variability in opioid dose-response relationships makes it difficult to individualise the dose and dosing interval to provide safe and effective analgesia. By examining how aging affects the pharmacokinetics (PK) and pharmacodynamics (PD) of opioids, it is possible to provide a rational basis for age adjustment in opioid dosing. Authors conclude that 'simulations with PK-PD models confirm the clinical impression that elderly patients n...

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The effect of medication reconciliation in elderly patients at hospital discharge

NeLM - Care of Older People — Thu, 02 Feb 2012 05:00:00 +0100

Source: International Journal of Clinical Pharmacy Area: Evidence > Medicines Management > References Objective: To assess the impact of medication reconciliation interventions on medication error rates when elderly patients are discharged from hospital to community care or nursing homes. Setting: Elderly patients (older than 65 years) in Sweden, living in nursing homes or in their own homes with care provided by the community nursing system. Method: All medical records containing information on drug treatment were collected from hospital departments, the community care service and GPs. We then identified whether there were any changes in the transfer of information i.e. if the drugs were not the same as before the transfer. Two different persons independently...

Reducing the burden of morbidity and medical utilization of older patients by outpatient geriatric services: Implications to primary health‐care settings

Geriatrics and Gerontology International — Thu, 02 Feb 2012 05:00:00 +0100

Conclusion: Outpatient GEM could effectively reduce growth of BOM and medical utilization for relatively healthy elderly patients in Taiwan where elderly patients haverelatively free access to general and specialty care. The results of this study implied the potential benefits of systematically implementing GEM in primary health‐care settings to improve the quality of care and slow down the growth of BOM for elderly patients. Geriatr Gerontol Int 2012; ••: ••–••. (Source: Geriatrics and Gerontology International)

Perceived age of facial features is a significant diagnosis criterion for age‐related carotid atherosclerosis in Japanese subjects: J‐SHIPP study

Geriatrics and Gerontology International — Thu, 02 Feb 2012 05:00:00 +0100

Conclusion: These findings show that carotid atherosclerosis is related to perceived age. This association might underlie previous findings showing that perceived age predicts life expectancy. Geriatr Gerontol Int 2012; ••: ••–••. (Source: Geriatrics and Gerontology International)

Effects of once weekly dual‐task training in older adults: A pilot randomized controlled trial

Geriatrics and Gerontology International — Thu, 02 Feb 2012 05:00:00 +0100

Conclusion: Once weekly group circuit training focusing on balance, gait and agility, with or without simultaneous cognitive tasks, resulted in significantly improved walking speed among older adults. Group‐format dual‐task training once per week did not improve walking time or dual‐task cost on an obstacle negotiation task. Geriatr Gerontol Int 2012; ••: ••–••. (Source: Geriatrics and Gerontology International)

Depressive symptoms and level of physical activity in patients with Alzheimer's disease

Geriatrics and Gerontology International — Thu, 02 Feb 2012 05:00:00 +0100

Conclusions: The prevalence of depressive symptoms in the sample was 35.13%. Patients who were more active had lower rates of depressive symptoms. Geriatr Gerontol Int 2012; ••: ••–••. (Source: Geriatrics and Gerontology International)

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3‐(2,4‐Dimethoxybenzylidene)‐anabaseine: A promising candidate drug for Alzheimer's disease?

Geriatrics and Gerontology International — Thu, 02 Feb 2012 05:00:00 +0100

This article reviews these properties and explains to what extent they could be valuable to control symptomatology and/or neurodegeneration in Alzheimer's disease. Geriatr Gerontol Int 2012; ••: ••–••. (Source: Geriatrics and Gerontology International)

Are we treating the elderly with breast cancer to the same standard as younger patients?

Future Medicine: Aging Health — Thu, 02 Feb 2012 04:00:13 +0100

Aging Health , February 2012, Vol. 8, No. 1, Pages 1-3. (Source: Future Medicine: Aging Health)

Candidacy for Kidney Transplantation of Older AdultsCandidacy for Kidney Transplantation of Older Adults

Medscape Today Headlines — Thu, 02 Feb 2012 04:00:00 +0100

This study suggests a risk prediction model for KT outcomes specific to older adults. Journal of the American Geriatrics Society (Source: Medscape Today Headlines)

Adult Children of Stroke Sufferers May Show Signs of Brain Aging, Too

The Doctors Lounge - Cardiology — Wed, 01 Feb 2012 18:00:00 +0100

Offspring may experience physical, mental changes that can precede stroke (Source: The Doctors Lounge - Cardiology)

Do anticholinergic drugs contribute to functional and cognitive decline?

Future Medicine: Aging Health — Wed, 01 Feb 2012 14:53:43 +0100

Aging Health , February 2012, Vol. 8, No. 1, Pages 57-60. (Source: Future Medicine: Aging Health)

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The elderly inflammatory bowel disease patient and osteoporosis

Future Medicine: Aging Health — Wed, 01 Feb 2012 14:53:42 +0100

Aging Health , February 2012, Vol. 8, No. 1, Pages 31-42. (Source: Future Medicine: Aging Health)

Minimally invasive surgery for aortic stenosis in the geriatric patient: where are we now?

Future Medicine: Aging Health — Wed, 01 Feb 2012 14:53:41 +0100

Aging Health , February 2012, Vol. 8, No. 1, Pages 17-30. (Source: Future Medicine: Aging Health)

Early intranasal insulin therapy halts progression of neurodegeneration: progress in Alzheimer’s disease therapeutics

Future Medicine: Aging Health — Wed, 01 Feb 2012 14:53:39 +0100

Aging Health , February 2012, Vol. 8, No. 1, Pages 61-64. (Source: Future Medicine: Aging Health)

Nutrition in aging and disease: update on biological sciences

Future Medicine: Aging Health — Wed, 01 Feb 2012 14:53:38 +0100

Aging Health , February 2012, Vol. 8, No. 1, Pages 13-16. (Source: Future Medicine: Aging Health)

Can optimism decrease the risk of illness and disease among the elderly?

Future Medicine: Aging Health — Wed, 01 Feb 2012 14:53:38 +0100

Aging Health , February 2012, Vol. 8, No. 1, Pages 5-8. (Source: Future Medicine: Aging Health)

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New-onset headaches in the elderly: an indicator of underlying disease

Future Medicine: Aging Health — Wed, 01 Feb 2012 14:53:37 +0100

Aging Health , February 2012, Vol. 8, No. 1, Pages 79-88. (Source: Future Medicine: Aging Health)

Dementia and sleep disturbances

Future Medicine: Aging Health — Wed, 01 Feb 2012 14:53:36 +0100

Aging Health , February 2012, Vol. 8, No. 1, Pages 65-78. (Source: Future Medicine: Aging Health)

A collaborative expert literature review of pain education, assessment and management

Future Medicine: Aging Health — Wed, 01 Feb 2012 14:53:35 +0100

Aging Health , February 2012, Vol. 8, No. 1, Pages 43-54. (Source: Future Medicine: Aging Health)

Anxiety and verbal memory performance in APOE-4 carriers and noncarriers aged 50 years and above

Future Medicine: Aging Health — Wed, 01 Feb 2012 14:53:34 +0100

Aging Health , February 2012, Vol. 8, No. 1, Pages 99-104. (Source: Future Medicine: Aging Health)

Common dietary supplements for cognitive health

Future Medicine: Aging Health — Wed, 01 Feb 2012 14:53:33 +0100

Aging Health , February 2012, Vol. 8, No. 1, Pages 89-97. (Source: Future Medicine: Aging Health)

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Acknowledgements

Future Medicine: Aging Health — Wed, 01 Feb 2012 14:53:32 +0100

Aging Health , February 2012, Vol. 8, No. 1, Pages 105-105. (Source: Future Medicine: Aging Health)

Bulletin Board

Future Medicine: Aging Health — Wed, 01 Feb 2012 14:53:31 +0100

Aging Health , February 2012, Vol. 8, No. 1, Pages 9-12. (Source: Future Medicine: Aging Health)

Study: Stents as Good as Surgery at Keeping Neck Arteries Open

MedicineNet Senior Health General — Wed, 01 Feb 2012 07:00:00 +0100

Title: Study: Stents as Good as Surgery at Keeping Neck Arteries OpenCategory: Health NewsCreated: 2/1/2012 11:01:00 AMLast Editorial Review: 2/1/2012 (Source: MedicineNet Senior Health General)

Pediatricians' Group Recommends HPV Vaccine for Boys

MedicineNet Senior Health General — Wed, 01 Feb 2012 07:00:00 +0100

Title: Pediatricians' Group Recommends HPV Vaccine for BoysCategory: Health NewsCreated: 2/1/2012 10:06:00 AMLast Editorial Review: 2/1/2012 (Source: MedicineNet Senior Health General)

Exercise a Good Pick-Me-Up After Cancer Treatment: Study

MedicineNet Senior Health General — Wed, 01 Feb 2012 07:00:00 +0100

Title: Exercise a Good Pick-Me-Up After Cancer Treatment: StudyCategory: Health NewsCreated: 2/1/2012 10:06:00 AMLast Editorial Review: 2/1/2012 (Source: MedicineNet Senior Health General)

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Fatty Diet Before Pregnancy Linked to Gestational Diabetes

MedicineNet Senior Health General — Wed, 01 Feb 2012 07:00:00 +0100

Title: Fatty Diet Before Pregnancy Linked to Gestational DiabetesCategory: Health NewsCreated: 1/31/2012 6:05:00 PMLast Editorial Review: 2/1/2012 (Source: MedicineNet Senior Health General)

Popular Diabetes Drug Might Cut Pancreatic Cancer Risk: Study

MedicineNet Senior Health General — Wed, 01 Feb 2012 07:00:00 +0100

Title: Popular Diabetes Drug Might Cut Pancreatic Cancer Risk: StudyCategory: Health NewsCreated: 1/31/2012 4:05:00 PMLast Editorial Review: 2/1/2012 (Source: MedicineNet Senior Health General)

U.S. Advisers Explain Request to Censor Bird Flu Research

MedicineNet Senior Health General — Wed, 01 Feb 2012 07:00:00 +0100

Title: U.S. Advisers Explain Request to Censor Bird Flu ResearchCategory: Health NewsCreated: 1/31/2012 4:05:00 PMLast Editorial Review: 2/1/2012 (Source: MedicineNet Senior Health General)

Health Highlights: Jan. 31, 2012

MedicineNet Senior Health General — Wed, 01 Feb 2012 07:00:00 +0100

Title: Health Highlights: Jan. 31, 2012Category: Health NewsCreated: 1/31/2012 4:05:00 PMLast Editorial Review: 2/1/2012 (Source: MedicineNet Senior Health General)

Pain (Acute and Chronic)

MedicineNet Senior Health General — Wed, 01 Feb 2012 07:00:00 +0100

Title: Pain (Acute and Chronic)Category: Doctor's ViewsCreated: 11/30/2004Last Editorial Review: 2/1/2012 (Source: MedicineNet Senior Health General)

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Rheumatoid Arthritis: Questions for Your Doctor

MedicineNet Senior Health General — Wed, 01 Feb 2012 07:00:00 +0100

Title: Rheumatoid Arthritis: Questions for Your DoctorCategory: Doctor's ViewsCreated: 8/6/2001 4:16:00 PMLast Editorial Review: 2/1/2012 (Source: MedicineNet Senior Health General)

Arthritis - Whether Weather Affects Arthritis

MedicineNet Senior Health General — Wed, 01 Feb 2012 07:00:00 +0100

Title: Arthritis - Whether Weather Affects ArthritisCategory: Doctor's ViewsCreated: 9/10/2000Last Editorial Review: 2/1/2012 (Source: MedicineNet Senior Health General)

Coping With Chronic Rheumatic Diseases

MedicineNet Senior Health General — Wed, 01 Feb 2012 07:00:00 +0100

Title: Coping With Chronic Rheumatic DiseasesCategory: Doctor's ViewsCreated: 8/4/2000 3:27:00 PMLast Editorial Review: 2/1/2012 (Source: MedicineNet Senior Health General)

Nonsteroidal Anti-inflammatory Drugs and Ulcers

MedicineNet Senior Health General — Wed, 01 Feb 2012 07:00:00 +0100

Title: Nonsteroidal Anti-inflammatory Drugs and UlcersCategory: Diseases and ConditionsCreated: 12/31/1997Last Editorial Review: 2/1/2012 (Source: MedicineNet Senior Health General)

[Endoscopy in geriatric patients positionspaper of the working group geriatric gastroenterology].

Zeitschrift fur Gastroenterologie — Wed, 01 Feb 2012 05:00:00 +0100

Authors: Staritz M Abstract The relevance of endoscopic diagnostic and therapeutic interventions is on a constant rise. However, specific aspects of the treatment of geriatric patients have only been tackled to a rather limited extent so far. The present contribution pinpoints illustratively the status quo on this issue and provides directions for further research which should be conducted in future studies supported by the working group on geriatric gastroenterology. PMID: 22298099 [PubMed - in process] (Source: Zeitschrift fur Gastroenterologie)

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Net costs of dementia in Sweden – An Incidence Based 10 Year Simulation Study

International Journal of Geriatric Psychiatry — Wed, 01 Feb 2012 05:00:00 +0100

Cochlear implant performance in geriatric patients

The Laryngoscope — Wed, 01 Feb 2012 05:00:00 +0100

Conclusions:Geriatric cochlear implant patients have a similar learning curve to the younger adults and in speech tests in quiet show a comparable performance. However their performance is significantly lower in noisy surroundings. This may be due to the central presbycusis in patients older than 70 years and should be taken into account in postoperative fitting of geriatric patients. Further prospective studies are required to evaluate the role of special rehabilitation methods and cognitive training to improve the speech perception in noise in geriatric CI patients. (Source: The Laryngoscope)

CSF Levels of Hypocretin-1 (Orexin-A) Peak during Early Infancy in Humans

Sleep — Wed, 01 Feb 2012 03:52:03 +0100

Conclusions:The present findings indicate that in human infants, CSF hypocretin-1 increases during the third embryonic trimester and is highest at 4 months of life. Thereafter, and consistent with previously published results, hypocretin levels are lower and stable until the geriatric age. This pattern may reflect the role of hypocretin in the dramatic process of sleep and wakefulness consolidation that occurs during early infancy.Citation:Aran A; Shors I; Lin L; Mignot E; Schimmel MS. CSF levels of hypocretin-1 (orexin-A) peak during early infancy in humans. SLEEP 2012;35(2):187-191. (Source: Sleep)

Self- and Informant Ratings of Personality in Mild Cognitive Impairment, Reviewed

Dementia and Geriatric Cognitive Disorders — Tue, 31 Jan 2012 23:00:00 +0100

Dement Geriatr Cogn Disord 2011;32:387–393 (DOI:10.1159/000330695) (Source: Dementia and Geriatric Cognitive Disorders)

Association between Nerve Growth Factor Gene Polymorphism and Executive Dysfunction in Japanese Patients with Early-Stage Alzheimer’s Disease and Amnestic Mild Cognitive Impairment

Dementia and Geriatric Cognitive Disorders — Tue, 31 Jan 2012 23:00:00 +0100

Dement Geriatr Cogn Disord 2011;32:379–386 (DOI:10.1159/000335355) (Source: Dementia and Geriatric Cognitive Disorders)

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Review of Cerebral Microangiopathy and Alzheimer’s Disease: Relation between White Matter Hyperintensities and Microbleeds

Dementia and Geriatric Cognitive Disorders — Tue, 31 Jan 2012 23:00:00 +0100

Dement Geriatr Cogn Disord 2011;32:367–378 (DOI:10.1159/000335568) (Source: Dementia and Geriatric Cognitive Disorders)

Using the Mini-Mental State Examination to Screen for Delirium in Elderly Patients with Hip Fracture

Dementia and Geriatric Cognitive Disorders — Tue, 31 Jan 2012 23:00:00 +0100

Dement Geriatr Cogn Disord 2011;32:394–400 (DOI:10.1159/000335743) (Source: Dementia and Geriatric Cognitive Disorders)

Alternative to Colonoscopy Spots Cancers, Too

The Doctors Lounge - Oncology — Tue, 31 Jan 2012 22:00:00 +0100

Study examines repeat sigmoidoscopy, a somewhat less-invasive screening method (Source: The Doctors Lounge - Oncology)

Management of newly diagnosed patients with type 2 diabetes: what are the attitudes of physicians? A SUBITO!AMD survey on the early diabetes treatment in Italy

Acta Diabetologica — Tue, 31 Jan 2012 16:45:12 +0100

Abstract Early intensive therapy in type 2 diabetes can prevent complications. Nevertheless, metabolic control is often sub-optimal in newly diagnosed patients. This web-based survey aimed to evaluate opinions of physicians about treatment, priorities, and barriers in the care of patients first referred to diabetes clinics. Data on physician attitudes toward therapeutic preferences for two clinical case models (same clinical profile, except HbA1c levels of 8.6 and 7.3% at the first access, respectively) were collected. Participants were asked to rank from 1 (most important) to 6 (least important) a list of priorities and barriers associated with the care of new patients. Overall, 593 physicians participated. In both case models, metformin and education were primary options...

“A Summer Tragedy”: A Geriatric Case Study

Journal of General Internal Medicine — Tue, 31 Jan 2012 07:11:12 +0100

Content Type Journal ArticleCategory Healing Arts: Text and ContextPages 1-2DOI 10.1007/s11606-011-1967-3Authors Ronald H. Lands, Department of Medicine, Associate Professor of Medicine, University of Tennessee, Knoxville, 1924 Alcoa Hwy, Knoxville, TN 37924 USA Journal Journal of General Internal MedicineOnline ISSN 1525-1497Print ISSN 0884-8734 (Source: Journal of General Internal Medicine)

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Poor bone microarchitecture in older men with impaired physical performance—the STRAMBO study

Osteoporosis International — Tue, 31 Jan 2012 07:05:11 +0100

Conclusion In older men, poor physical performance is associated with lower hip aBMD and poor bone microarchitecture (mainly at the distal tibia). Content Type Journal ArticleCategory Original ArticlePages 1-12DOI 10.1007/s00198-012-1906-0Authors S. Blaizot, INSERM UMR 1033, Université de Lyon, Lyon, FranceS. Boutroy, INSERM UMR 1033, Université de Lyon, Lyon, FranceN. Vilayphiou, INSERM UMR 1033, Université de Lyon, Lyon, FranceS. Boonen, Division of Gerontology and Geriatrics and Center for Musculoskeletal Research, Division of Geriatric Medicine and Center for Metabolic Bone Diseases, Leuven University Hospital Department of Internal Medicine, Leuven, BelgiumR. Chapurlat, INSERM UMR 1033, Université de Lyon, Lyon, FranceP. Szulc, INSERM UMR 1033, Université d...

Frailty and sarcopenia: definitions and outcome parameters

Osteoporosis International — Tue, 31 Jan 2012 07:05:09 +0100

Abstract An operational definition of musculoskeletal decline in older people is needed to allow development of interventions for prevention or treatment, as was developed for the treatment of osteoporosis. Frailty and sarcopenia are linked, but distinct, correlates of musculoskeletal aging that have many causes, including age-related changes in body composition, inflammation, and hormonal imbalance. With the emergence of a number of exciting candidate therapies to retard the loss of muscle mass with aging, the derivation of a consensual definition of sarcopenia and physical frailty becomes an urgent priority. Although several consensual definitions have been proposed, these require clinical validation. An operational definition, which might provide a threshold for treatme...

Pets Help Women Cope With HIV/AIDS

MedicineNet Alzheimer — Tue, 31 Jan 2012 07:00:00 +0100

Title: Pets Help Women Cope With HIV/AIDSCategory: Health NewsCreated: 1/30/2012 4:06:00 PMLast Editorial Review: 1/31/2012 (Source: MedicineNet Alzheimer)

Alzheimer's disease and age-related macular degeneration have different genetic models for complement gene variation.

Neurobiology of Aging — Tue, 31 Jan 2012 05:00:00 +0100

Authors: Proitsi P, Lupton MK, Dudbridge F, Tsolaki M, Hamilton G, Daniilidou M, Pritchard M, Lord K, Martin BM, Craig D, Todd S, McGuinness B, Hollingworth P, Harold D, Kloszewska I, Soininen H, Mecocci P, Velas B, Gill M, Lawlor B, Rubinsztein DC, Brayne C, Passmore PA, Williams J, Lovestone S, Powell JF Abstract Alzheimer's disease (AD) and age-related macular degeneration (AMD) are both neurodegenerative disorders which share common pathological and biochemical features of the complement pathway. The aim of this study was to investigate whether there is an association between well replicated AMD genetic risk factors and AD. A large cohort of AD (n = 3898) patients and controls were genotyped for single nucleotide polymorphisms (SNPs) in the complement factor H (CFH), the Age-re...

Expression pattern of oxidative stress and antioxidant defense-related genes in the aging Fischer 344/NHsd rat cochlea.

Neurobiology of Aging — Tue, 31 Jan 2012 05:00:00 +0100

Authors: Tanaka C, Coling DE, Manohar S, Chen GD, Hu BH, Salvi R, Henderson D Abstract The biological mechanisms that give rise to age-related hearing loss (ARHL) are still poorly understood. However, there is growing recognition that oxidative stress may be an important factor. To address this issue, we measured the changes in the expression of cochlear oxidative stress and antioxidant defense-related genes in young (2 months old), middle-aged (12 months old), and old (21-25 months old) Fischer 344/NHsd (F344/NHsd) rats and compared gene expression changes with ARHL. A quantitative real-time reverse transcription polymerase chain reaction array revealed a significant age-related downregulation of only 1 gene, stearoyl-coenzyme A desaturase 1, and upregulation of 12 genes: 24-dehyd...

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Acute moderate exercise enhances compensatory brain activation in older adults.

Neurobiology of Aging — Tue, 31 Jan 2012 05:00:00 +0100

Authors: Hyodo K, Dan I, Suwabe K, Kyutoku Y, Yamada Y, Akahori M, Byun K, Kato M, Soya H Abstract A growing number of reports state that regular exercise enhances brain function in older adults. Recently a functional near-infrared spectroscopy (fNIRS) study revealed that an acute bout of moderate exercise enhanced activation of the left dorsolateral prefrontal cortex (L-DLPFC) associated with Stroop interference in young adults. Whether this acute effect is also applicable to older adults was examined. Sixteen older adults performed a color-word matching Stroop task before and after 10 minutes of exercise on a cycle ergometer at a moderate intensity. Cortical hemodynamics of the prefrontal area was monitored with a fNIRS during the Stroop task. We analyzed Stroop interference (inc...

Unmarried Boomers Confront Old Age: A National Portrait.

The Gerontologist — Tue, 31 Jan 2012 05:00:00 +0100

Authors: Lin IF, Brown SL Abstract Purpose of the Study:Our study provides a national portrait of the Baby Boom generation, paying particular attention to the heterogeneity among unmarried Boomers and whether it operates similarly among women versus men. DESIGN AND METHODS: We used the 1980, 1990, and 2000 Census 5% samples and the 2009 American Community Survey (ACS) to document the trends in the share and marital status composition of the unmarried population during midlife. Using the 2009 ACS, we developed a sociodemographic portrait of Baby Boomers according to marital status. RESULTS: One in three Baby Boomers was unmarried. The vast majority of these unmarried Boomers were either divorced or never-married; just 10% were widowed. Unmarried Boomers faced greater economic, healt...

Baby Boom Caregivers: Care in the Age of Individualization.

The Gerontologist — Tue, 31 Jan 2012 05:00:00 +0100

This study examines how Baby Boomers in Quebec, Canada, perceive and play their role as caregivers and how this might differ from their parents' generation. DESIGN AND METHODS: This was a qualitative and empirical study using an interpretive constructivist design. We interviewed 39 Baby Boomers caring for a family member with a semistructured guide that examined respondents' identification with their social generation, their relationship to and values regarding caregiving, and the reality of the caregiving they offered. RESULTS: In contrast to our perceptions of previous generations, the majority of interviewees refuse to be confined to the sole identity of caregiver, as they work to juggle caregiving, work, family, and social commitments. To succeed in this juggling act, they have high ex...

Out of the Closet and Into the Trenches: Gay Male Baby Boomers, Aging, and HIV/AIDS.

The Gerontologist — Tue, 31 Jan 2012 05:00:00 +0100

This article argues for the application of this latter approach to research into the lasting impacts of HIV/AIDS on this cohort of gay men. We examine HIV/AIDS mortality within this cohort at the epidemic's height, these deaths' concentration in urban gay communities, and the growing and increasingly diverse population of HIV-positive gay men born in the Baby Boom Years. Our conclusion suggests that a fuller examination of the role of HIV/AIDS in the lives of gay male Baby Boomers, using a life course perspective, is critical to appreciating this generation's heterogeneity and to expanding knowledge of how later life is shaped by the intersection between historical events, personal biography, and social and community ties. PMID: 22298746 [PubMed - as supplied by publisher] (Source: The...

Cohort Differences in the Availability of Informal Caregivers: Are the Boomers at Risk?

The Gerontologist — Tue, 31 Jan 2012 05:00:00 +0100

Authors: Ryan LH, Smith J, Antonucci TC, Jackson JS Abstract Purpose of the Study:We compare the close family resources of Baby Boomers (BBs) to previous cohorts of older adults at population level and then examine individual-level cohort comparisons of age-related trajectories of informal care availability from midlife into old age. DESIGN AND METHODS: Population data from the U.S. Census and from the Health and Retirement Study (HRS) are used to identify a cohort similar to the BBs on marital status and fertility rates. Using generalized linear mixed models and 10-year longitudinal data from Depression and WWII parents (DWP; n = 1,052) and the parents of BBs (PBB; n = 3,573) in the HRS, we examine cohort differences in the time-varying likelihoods of being married and of having a...

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New GSA resources lay foundation for relieving seniors' pain

EurekAlert! - Social and Behavioral Science — Tue, 31 Jan 2012 05:00:00 +0100

(The Gerontological Society of America) The pain suffered by older adults is the shared focus of the two newest entries in the Gerontological Society of America's "From Publication to Practice" series. Together they address both pain management and new labeling changes for one of the most popular pain medications, acetaminophen. Both issues aim to provide readers with information on how new advances in pain prevention, treatment, and management may improve care and quality of life for older adults. (Source: EurekAlert! - Social and Behavioral Science)

A Hospitalist-run Acute Care for the Elderly ServiceA Hospitalist-run Acute Care for the Elderly Service

Medscape Today Headlines — Tue, 31 Jan 2012 04:00:00 +0100

This study evaluates how one such program helped minimize risks and improve outcomes. Journal of Hospital Medicine (Source: Medscape Today Headlines)

Enter our Robbie Savage competition to win a signed copy of his best-selling autobiography

Alzheimers Society — Mon, 30 Jan 2012 09:35:00 +0100

We've got a signed copy of former footballer and Alzheimer's Society ambassador, Robbie Savage's, best-selling autobiography 'Savage!' up for grabs. (Source: Alzheimers Society)

Age UK Care in Crisis report: Alzheimer's Society comment

Alzheimers Society — Mon, 30 Jan 2012 08:09:00 +0100

Today (Monday, 30 January), Age UK launches its Care in Crisis report which shows that spending on social care for older people in England has fallen by half a billion pounds since 2010. (Source: Alzheimers Society)

ATP13A2 mutations impair mitochondrial function in fibroblasts from patients with Kufor-Rakeb syndrome.

Neurobiology of Aging — Mon, 30 Jan 2012 05:00:00 +0100

Authors: Grünewald A, Arns B, Seibler P, Rakovic A, Münchau A, Ramirez A, Sue CM, Klein C Abstract Mutations in ATP13A2 cause autosomal-recessive parkinsonism (Kufor-Rakeb syndrome; KRS). Because several other parkinsonism-associated proteins have been connected to mitochondrial function and mitophagy, we studied the impact of endogenous mutations in ATPase type 13A2 (ATP13A2) on mitochondria in fibroblasts from KRS patients compared with controls. In patients, we detected decreased adenosine triphosphate (ATP) synthesis rates, increased mitochondrial DNA levels, a higher frequency of mitochondrial DNA lesions, increased oxygen consumption rates, and increased fragmentation of the mitochondrial network. Importantly, overexpression of wild-type ATP13A2 rescued the respiration phen...

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Ensuring a nurse practitioner workforce prepared to care for older adults: Findings from a national survey of adult and geriatric nurse practitioner programs

Journal of the American Academy of Nurse Practitioners — Mon, 30 Jan 2012 05:00:00 +0100

Conclusions: The survey and the focus group findings indicate that there is a strong need for (a) access to a set of nationally recognized competencies for A‐GNPs; (b) teaching/learning resources to support faculty in implementation of A‐GNP programs; and (c) formal faculty development opportunities to facilitate faculty efforts to engage in curricular redesign and innovations and assure that NP students acquire strong competence in gerontology content.Implications for practice: The transition to A‐GNP has implications not only for NP faculty but also for practicing NPs. Almost all NPs care for older adults in a variety of settings. However, most of these NPs are not specialists in geriatrics. This article provides a context for self‐assessment by these NPs of their own needs relat...

An exploration of nursing home managers' knowledge of and attitudes towards the management of pain in residents with dementia

International Journal of Geriatric Psychiatry — Mon, 30 Jan 2012 05:00:00 +0100

ConclusionsThe study has revealed that accurate pain assessment, training of nursing staff and a standardised approach to pain management (the use of pain management guidelines) within nursing homes all have a significant part to play in the successful management of pain in residents with dementia. Copyright © 2012 John Wiley & Sons, Ltd. (Source: International Journal of Geriatric Psychiatry)

Family Perceptions of End‐of‐Life Care for Long‐Term Care Residents with Dementia: Differences Between the United States and the Netherlands

Journal of the American Geriatrics Society — Mon, 30 Jan 2012 05:00:00 +0100

ConclusionBecause previous research favored care in the Netherlands to that in the United States, findings suggest improvement in end‐of‐life care and outcomes in the United States and stability in the Netherlands. Greater hospice use does not explain improvements in the United States directly and may relate, at least in part, to care provided by long‐term care staff themselves. Better understanding of the nature and process of these improvements may suggest areas for additional improvement. (Source: Journal of the American Geriatrics Society)

Characteristics, Services, and Infection Control Practices of New York City Assisted Living Facilities, 2010

Journal of the American Geriatrics Society — Mon, 30 Jan 2012 05:00:00 +0100

ConclusionNYC ALFs were varied in terms of nursing services offered, characteristics, and residents’ needs; therefore, public health agencies may need to be flexible in their assistance. Public health agencies should consider strengthening relationships with ALFs to identify unmet needs and gaps in services. (Source: Journal of the American Geriatrics Society)

Effects of Intervention Using a Community‐Based Walking Program for Prevention of Mental Decline: A Randomized Controlled Trial

Journal of the American Geriatrics Society — Mon, 30 Jan 2012 05:00:00 +0100

ConclusionWalking programs may provide benefits in some aspects of cognition, QOL, and functional capacity including social interaction in elderly community members. This study could serve as the basis for implementation of a community‐based intervention to prevent mental decline. (Source: Journal of the American Geriatrics Society)

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New‐Onset Treatment‐Dependent Diabetes Mellitus and Hyperlipidemia Associated with Atypical Antipsychotic Use in Older Adults without Schizophrenia or Bipolar Disorder

Journal of the American Geriatrics Society — Mon, 30 Jan 2012 05:00:00 +0100

ConclusionUse of atypical antipsychotics in older adults for conditions other than schizophrenia and bipolar disorder was associated with incident treatment of diabetes mellitus but not of hyperlipidemia, suggesting that older adults may be susceptible to the adverse metabolic consequences of these agents. (Source: Journal of the American Geriatrics Society)

Effects of a Late‐Life Suicide Risk–Assessment Training on Multidisciplinary Healthcare Providers

Journal of the American Geriatrics Society — Mon, 30 Jan 2012 05:00:00 +0100

AbstractOlder adults are among the highest at risk for completing suicide, and they are more likely to seek mental health services from providers outside of traditional mental health care, but providers across the spectrum of care have limited training in suicide risk assessment and management and particularly lack training in suicide prevention for older adults. An educational program was developed to increase awareness and improve suicide risk assessment and management training for a range of healthcare providers who may see older adults in their care settings. One hundred thirty‐two participants from two Veterans Affairs Medical Centers participated in a 6.5‐hour‐long workshop in the assessment and management of suicide risk in older adults. Participants were asked to complete pre...

Quality of Life in Late‐Life Disability: “I Don't Feel Bitter Because I Am in a Wheelchair”

Journal of the American Geriatrics Society — Mon, 30 Jan 2012 05:00:00 +0100

ConclusionFactors that influence quality of life in late‐life disability were similar across ethnic groups. As the number of elderly adults from diverse backgrounds with late life disability increases in the United States, interventions should be targeted to maximize daily sense of control and dignity. (Source: Journal of the American Geriatrics Society)

The Disappearing Subject: Exclusion of People with Cognitive Impairment and Dementia from Geriatrics Research

Journal of the American Geriatrics Society — Mon, 30 Jan 2012 05:00:00 +0100

ConclusionPersons with cognitive impairment are frequently excluded from research, often without rationale or mention of exclusion as a limitation or any discussion of its potential effect on the evidence base in geriatrics. When necessary, exclusion should be done thoughtfully and with awareness that this may reduce the clinical utility of study findings. (Source: Journal of the American Geriatrics Society)

Nonpharmacological Approaches to the Management of Chronic Pain in Community‐Dwelling Older Adults: A Review of Empirical Evidence

Journal of the American Geriatrics Society — Mon, 30 Jan 2012 05:00:00 +0100

The objective of this literature review is to gain insight into the efficacy of nonpharmacological interventions in chronic pain management in community‐dwelling older adults. An extensive search of pertinent databases was performed to identify reports of studies of nonpharmacological (physical and psychosocial) pain interventions. The review identifies intervention studies that used randomized controlled trials (RCTs) and summarizes existing evidence of effectiveness of nonpharmacological interventions. A literature search yielded 28 RCT intervention studies (18 for physical interventions and 10 for psychosocial interventions) that met inclusion criteria and are included in this review. Twenty‐one studies (75%) identified in this review demonstrated statistically significant differenc...

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Associations between Drug Burden Index and Mortality in Older People in Residential Aged Care Facilities

Drugs — Sun, 29 Jan 2012 21:34:47 +0100

(Source: Drugs)

Potentially Inappropriate Prescribing in Older People with Dementia in Care Homes: A Retrospective Analysis

Drugs — Sun, 29 Jan 2012 21:34:47 +0100

(Source: Drugs)

Three-year Experience with Alendronate Treatment in Postmenopausal Osteoporotic Japanese Women with or without Renal Dysfunction: A Retrospective Study

Drugs — Sun, 29 Jan 2012 21:34:47 +0100

(Source: Drugs)

Long-Term Safety, Tolerability and Efficacy of Fesoterodine in Subjects with Overactive Bladder Symptoms Stratified by Age: Pooled Analysis of Two Open-Label Extension Studies

Drugs — Sun, 29 Jan 2012 21:34:47 +0100

(Source: Drugs)