MedWorm: Internal Medicine

Bivalirudin during Primary PCI in Acute Myocardial Infarction

AccessMedicine Updates — Sat, 21 Nov 2009 03:30:00 +0100

(Source: AccessMedicine Updates)

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Clinical presentation and molecular pathophysiology of autosomal dominant hemochromatosis caused by a novel ferroportin mutation

Hepatology — Sat, 21 Nov 2009 00:00:00 +0100

Conclusion: We report a novel pathological SLC40A1 variant associated with abnormal cell surface expression of ferroportin due to intracellular retention of the mutant protein. These findings predict macrophage-type ferroportin disease, the phenotype observed in this kindred. Study of the molecular cell biology of ferroportin and its mutants is key to understanding the pathogenesis of this increasingly recognized form of hemochromatosis, which responds poorly to conventional therapy. (HEPATOLOGY 2009.) (Source: Hepatology)

Cangrelor not CHAMPION for PCI patients

MedWire News - Thrombosis — Fri, 20 Nov 2009 15:37:58 +0100

Two CHAMPION trials show disappointing results for the novel fast-acting intravenous platelet inhibitor cangrelor before or after percutaneous coronary intervention, with no reduction in the rate of death, myocardial infarction, or revascularization at 48 hours compared with clopidogrel treatment. (Source: MedWire News - Thrombosis)

Low Back Pain: Evaluating Presenting Symptoms in Elderly Patients

Medscape Internal Medicine Headlines — Fri, 20 Nov 2009 15:37:41 +0100

This review launches a new series on the evaluation of presenting symptoms in geriatric patients. Medscape Family Medicine (Source: Medscape Internal Medicine Headlines)

Unique Malpractice Risks of Ambulatory Surgery Centers

Medscape Internal Medicine Headlines — Fri, 20 Nov 2009 15:06:52 +0100

More physicians are setting up ambulatory surgery centers, but there are many malpractice risks that come with having a center. Here is what to watch out for. Medscape Business of Medicine (Source: Medscape Internal Medicine Headlines)

New Creative Approaches to Pancreatic Cancer Improve Drug Delivery

Medscape Internal Medicine Headlines — Fri, 20 Nov 2009 13:45:34 +0100

Pancreatic cancer remains the deadliest of cancer, but new approaches that improve the delivery of drugs to the tumor appear to hold promise. Medscape Medical News (Source: Medscape Internal Medicine Headlines)

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RE-DEEM: Dabigatran causes no safety concerns in phase II ACS trial

MedWire News - Thrombosis — Thu, 19 Nov 2009 15:44:11 +0100

When added to dual anti-platelet therapy, the orally administered direct thrombin inhibitor, dabigatran etexilate, results in a “low and acceptable bleeding rate” compared with placebo in patients who have suffered an acute myocardial infarction, according to data presentedat the American Heart Association 2009 Scientific Sessions in, Orlando, Florida, USA. (Source: MedWire News - Thrombosis)

Assessment of the Neck and Lymph Nodes in the Elderly Patient

Medscape Internal Medicine Headlines — Thu, 19 Nov 2009 15:37:54 +0100

Next in this important series on geriatric assessment: examining the neck and lymph nodes. Medscape Family Medicine (Source: Medscape Internal Medicine Headlines)

Tesamorelin Reduces Visceral Fat by up to 18% in HIV-Infected Men

Medscape Internal Medicine Headlines — Thu, 19 Nov 2009 14:32:34 +0100

The growth hormone precursor tesamorelin significantly reduces body fat and triglycerides and significantly increases insulin-like growth factor levels in HIV-positive men. Medscape Medical News (Source: Medscape Internal Medicine Headlines)

Promising New Cancer Drugs in the Pipeline

Medscape Internal Medicine Headlines — Thu, 19 Nov 2009 13:38:33 +0100

A number of novel and promising cancer therapies are currently in the pipeline, and researchers might be discovering new uses for older drugs. Medscape Medical News (Source: Medscape Internal Medicine Headlines)

RE-LY Trial

AccessMedicine Updates — Thu, 19 Nov 2009 03:30:00 +0100

(Source: AccessMedicine Updates)

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Irbesartan has no short-term effect on insulin resistance in hypertensive patients with additional cardiometabolic risk factors (i-RESPOND)

International Journal of Clinical Practice — Thu, 19 Nov 2009 00:00:00 +0100

Conclusion: Irbesartan did not show significant favourable effects on insulin resistance compared with HCTZ in this study; however, may have beneficial effects on inflammation and microalbuminuria in hypertensive patients with metabolic syndrome. (Source: International Journal of Clinical Practice)

Roy D. Bloom, MD - Improving Long-Term Outcomes in Kidney Transplant Recipients: A Case-Based Approach to the Prevention and Management of Post-Transplant Morbidity

Peerview CME/CE Video Podcast - Internal Medicine — Wed, 18 Nov 2009 18:49:25 +0100

Please be sure to view the accompanying (PDF) file for full CME/CNE/CPE information. (Source: Peerview CME/CE Video Podcast - Internal Medicine)

Roy D. Bloom, MD - Improving Long-Term Outcomes in Kidney Transplant Recipients: A Case-Based Approach to the Prevention and Management of Post-Transplant Morbidity

Peerview CME/CE Audio Podcast - Internal Medicine — Wed, 18 Nov 2009 18:49:25 +0100

Please be sure to view the accompanying (PDF) file for full CME/CNE/CPE information. (Source: Peerview CME/CE Audio Podcast - Internal Medicine)

CME/CNE/CPE Information - Improving Long-Term Outcomes in Kidney Transplant Recipients: A Case-Based Approach to the Prevention and Management of Post-Transplant Morbidity

Peerview CME/CE Video Podcast - Internal Medicine — Wed, 18 Nov 2009 18:49:23 +0100

Please view this PDF file for full CME/CNE/CPE information. You will need Adobe Acrobat reader software to access this file. (Source: Peerview CME/CE Video Podcast - Internal Medicine)

CME/CNE/CPE Information - Improving Long-Term Outcomes in Kidney Transplant Recipients: A Case-Based Approach to the Prevention and Management of Post-Transplant Morbidity

Peerview CME/CE Audio Podcast - Internal Medicine — Wed, 18 Nov 2009 18:49:23 +0100

Please view this PDF file for full CME/CNE/CPE information. You will need Adobe Acrobat reader software to access this file. (Source: Peerview CME/CE Audio Podcast - Internal Medicine)

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Rethinking Screening Mammography

Medscape Internal Medicine Headlines — Wed, 18 Nov 2009 15:37:33 +0100

What is the controversy about screening mammograms according to a recently published JAMA study? Dr. Andrew Kaunitz discusses if you should still recommend breast cancer screening in this video blog. Medscape Ob/Gyn & Women's Health (Source: Medscape Internal Medicine Headlines)

Bone Health of 40-Something HIV-Positive Men Similar to That of Uninfected Men Decades Older

Medscape Internal Medicine Headlines — Wed, 18 Nov 2009 14:45:27 +0100

The prevalence of osteoporosis among HIV-positive men in their 40s is similar to that of uninfected men in their 70s. Medscape Medical News (Source: Medscape Internal Medicine Headlines)

PLATO Trial

AccessMedicine Updates — Wed, 18 Nov 2009 03:30:01 +0100

(Source: AccessMedicine Updates)

HeartMate II: Continuous-flow left ventricular assist device outperforms pulsatile-flow device in advanced heart failure

MedWire News - Thrombosis — Wed, 18 Nov 2009 00:00:00 +0100

A continuous-flow left ventricular assist device achieved superior outcomes to a pulsatile-flow LVAD in patients with advanced heart failure. In the HeartMate II Destination Therapy clinical trial, 2-year survival for patients implanted with the continuous-flow device was more than double that of patients implanted with the pulsatile-flow device. (Source: MedWire News - Thrombosis)

FAIR-HF: Intravenous iron improves chronic heart failure outcomes

MedWire News - Thrombosis — Wed, 18 Nov 2009 00:00:00 +0100

Intravenous iron treatment improves multiple clinical outcomes in patients with chronic heart failure and reduced left ventricular ejection fraction, regardless of whether or not they also have anemia, according to data from the FAIR-HF study. (Source: MedWire News - Thrombosis)

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CME: Case 36-2009: A 23-Year-Old Man with Cough, Hoarseness, and Abnormalities on Chest Imaging