MedWorm: Medicine (General)

Cutera closes $5.1 million acquisition of Iridex

Modern Medicine — Wed, 08 Feb 2012 23:47:51 +0100

Cutera, a provider of laser and other light-based systems used by cosmetic surgeons, has finalized its $5.1 million cash purchase of the global aesthetic business of Iridex, Mountain View, Calif. (Source: Modern Medicine)

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Noninvasive DNA test is highly specific for fetal aneuploidy

Modern Medicine — Wed, 08 Feb 2012 23:47:51 +0100

Results from an international multicenter study suggest that a new plasma-based DNA test detects nearly all cases of trisomy 18 (Edwards syndrome) and trisomy 13 (Patau syndrome), in addition to Down syndrome, with low false-positive rates. (Source: Modern Medicine)

Software could help ID face-changing criminals

Modern Medicine — Wed, 08 Feb 2012 23:47:51 +0100

University of Notre Dame researchers have developed a new face-matching technique that may become an effective law enforcement tool to help identify criminals who have undergone plastic surgery to alter their looks. (Source: Modern Medicine)

Fat injection reconstruction combo shows promise

Modern Medicine — Wed, 08 Feb 2012 23:47:51 +0100

A new technique involving injections of fat followed by implant placement may prove a viable alternative for breast cancer patients who have undergone radiation therapy. (Source: Modern Medicine)

Business booms for tattoo removers, analysts say

Modern Medicine — Wed, 08 Feb 2012 23:47:51 +0100

The tattoo boom of recent years has spawned an additional growth industry. The ranks of tattoo removal practitioners have increased substantially over the past five years, with revenue rising at an average annual rate of about 21 percent to $65.6 million in 2012, market analysis firm IBISWorld reports. (Source: Modern Medicine)

Same Lung Injury Risk With Pre-Hospital Steroids (CME/CE)

MedPage Today Meeting Coverage — Wed, 08 Feb 2012 22:13:06 +0100

HOUSTON (MedPage Today) -- Pre-hospital steroid therapy did not reduce the risk of acute lung injury in critically ill patients and might have increased inhospital mortality risk, according to a study reported here. (Source: MedPage Today Meeting Coverage)

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Best Tweets - Selection of Twitter Favorites

Clinical Cases and Images — Wed, 08 Feb 2012 13:48:00 +0100

Because of a tendency for hands to be near mouths, we recommend #glutenfree hand lotions for celiacs.— Celiac Disease Ctr (@CureCeliac) February 7, 2012 Btw, is it usual for the receptionist to read out the blood results of a patient in front of the entire waiting room? The poor man!— richard horton (@richardhorton1) February 7, 2012 When the receptionist read out the cholesterol and blood glucose, the man asked: "Are they normal?" To which she said "Probably."— richard horton (@richardhorton1) February 7, 2012 Researching a topic is much easier than writing about it...— Dr. Ronan Kavanagh (@RonanTKavanagh) February 7, 2012 A new paper looks to decipher the ailments tied to eating gluten. More importantly, there's a journal called "Gut" on.wsj.com/AorvDJ— ...

Almost half of preventive services not offered during checkups

American Medical News — Wed, 08 Feb 2012 12:55:55 +0100

Patients often bring up other medical concerns and cut short the time devoted to meeting prevention guidelines. (Source: American Medical News)

Global payment gains traction in Massachusetts

American Medical News — Wed, 08 Feb 2012 12:55:55 +0100

Children's Hospital Boston and Partners HealthCare reached restructured contracts with insurers in an effort to control costs. (Source: American Medical News)

More patients pick up e-prescriptions than paper prescriptions

Modern Medicine — Wed, 08 Feb 2012 05:00:00 +0100

More patients pick up their first prescription when it’s sent to the pharmacy electronically, an industry survey shows. Convenience may not be the only reason. (Source: Modern Medicine)

Funding focuses on blinding eye disease

Modern Medicine — Wed, 08 Feb 2012 05:00:00 +0100

Blinding eye diseases will be the focus of $350,000 in research funded by Research to Prevent Blindness at the John A. Moran Eye Center of the University of Utah, Salt Lake City, and in the Department of Ophthalmology at the University of California, San Diego, School of Medicine. (Source: Modern Medicine)

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Former senators push health IT initiatives

Modern Medicine — Wed, 08 Feb 2012 05:00:00 +0100

A Washington, DC, think tank is pushing lawmakers to invest in healthcare information technology. Discover which influence-makers are involved—and what they’re recommending. (Source: Modern Medicine)

ACP to Congress: Don’t cut primary care workforce programs

Modern Medicine — Wed, 08 Feb 2012 05:00:00 +0100

The American College of Physicians urged Congress not to cut funding for the National Health Services Corps. Learn why the ACP says it’s so important. (Source: Modern Medicine)

5-ARI delays prostate cancer progression in men with low-risk disease

Modern Medicine — Wed, 08 Feb 2012 05:00:00 +0100

The 5-alpha-reductase inhibitor dutasteride (Avodart) appears to delay disease progression and the initiation of active treatment in men with low-risk, localized prostate cancer, results of a 3-year international clinical trial indicate. (Source: Modern Medicine)

Business booms for tattoo removers, analysts say

Modern Medicine — Wed, 08 Feb 2012 05:00:00 +0100

Brachytherapy reduces death in high-risk PCa patients

Modern Medicine — Wed, 08 Feb 2012 05:00:00 +0100

Brachytherapy alone, or in combination with external beam radiation therapy (EBRT), significantly reduces mortality rates in patients with high-risk prostate cancer, report the authors of a study from Thomas Jefferson University, Philadelphia. (Source: Modern Medicine)

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Derm residents cheating: ABD responds to CNN story

Modern Medicine — Wed, 08 Feb 2012 05:00:00 +0100

The American Board of Dermatology has warned residents that the practice of using so-called “airplane notes” to cheat on certification exams is illegal, the board’s executive director says. (Source: Modern Medicine)

Valeant withdraws offer for ISTA

Modern Medicine — Wed, 08 Feb 2012 05:00:00 +0100

Valeant Pharmaceuticals International Inc. has withdrawn its offer to acquire ISTA Pharmaceuticals Inc. for $7.50 per share in cash. (Source: Modern Medicine)

MGMA: Productive, profitable practices focus on workflow

Modern Medicine — Wed, 08 Feb 2012 05:00:00 +0100

MGMA reveals that its top-performing groups share characteristics in four areas. Find out what it takes to thrive in this tough economy. (Source: Modern Medicine)

Nursing group updates guidelines on preventing catheter-associated UTIs

Modern Medicine — Wed, 08 Feb 2012 05:00:00 +0100

A new American Association of Critical-Care Nurses (AACN) Practice Alert stresses the use of pre- and post-catheterization assessments to gauge proper catheter use and to monitor early signs of urinary tract infection. (Source: Modern Medicine)

'Gatekeeper' identified for skin inflammation

Modern Medicine — Wed, 08 Feb 2012 05:00:00 +0100

A new study has identified key signals that regulate protective and sometimes pathological skin inflammation, and also identifies a “gatekeeper” that, when lost, can cause inflammatory skin disease in the absence of injury or infection. (Source: Modern Medicine)

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Government abandons study of Medicare opt-outs

Modern Medicine — Wed, 08 Feb 2012 05:00:00 +0100

A quest to determine why physicians drop Medicare from their practices, and what effect it has on healthcare has ended in failure. See what roadblock got in the way. (Source: Modern Medicine)

FDA clears second-generation dry eye device

Modern Medicine — Wed, 08 Feb 2012 05:00:00 +0100

TearScience Inc. has received FDA clearance for a second-generation version of its proprietary device that treats evaporative dry eye by liquefying and evacuating obstructions in the meibomian glands (LipiFlow Thermal Pulsation System). (Source: Modern Medicine)

Rhode Island practice sold

Modern Medicine — Wed, 08 Feb 2012 05:00:00 +0100

Private equity firm Candescent Partners has acquired vision services provider Koch Eye Associates. (Source: Modern Medicine)

FDA approves kinase inhibitor for advanced RCC

Modern Medicine — Wed, 08 Feb 2012 05:00:00 +0100

The FDA has approved the oral kinase inhibitor axitinib (Inlyta) for the treatment of patients with advanced renal cell carcinoma after failure of one prior systemic therapy. (Source: Modern Medicine)

AAO, ASCRS offer guidance on femtosecond billing

Modern Medicine — Wed, 08 Feb 2012 05:00:00 +0100

The American Academy of Ophthalmology and the American Society of Cataract and Refractive Surgery have issued guidelines to assist ophthalmologists in determining their ability to charge Medicare and/or its beneficiaries for use of a femtosecond laser during cataract surgery. (Source: Modern Medicine)

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Physician, technology groups clash on ICD-10

Modern Medicine — Wed, 08 Feb 2012 05:00:00 +0100

One major group is fighting the switch, and another is urging its members not to wait. Learn the reasoning behind their positions. (Source: Modern Medicine)

New report details PBA-state partnerships

Modern Medicine — Wed, 08 Feb 2012 05:00:00 +0100

The positive effects on vision health that have arisen from partnerships between Prevent Blindness America affiliates and their respective state public health entities are detailed in the organization’s latest report. (Source: Modern Medicine)

Dr. Ruth Williams becomes new AAO president

Modern Medicine — Wed, 08 Feb 2012 05:00:00 +0100

Ruth D. Williams, MD, has begun her term as the 115th president of the American Academy of Ophthalmology. (Source: Modern Medicine)

Web resource helps assess life expectancy

Modern Medicine — Wed, 08 Feb 2012 05:00:00 +0100

Researchers have completed a systematic review of prognostic indices used to calculate a patient's life expectancy, and created a Web site that puts these indices in one central location. (Source: Modern Medicine)

PRK versus femto-LASIK: Optical quality

Modern Medicine — Wed, 08 Feb 2012 05:00:00 +0100

PRK seems to be associated with better optical quality 3 months postoperatively compared with femto-LASIK. The factors leading to negative effects in femto-LASIK might be the creation of an interface and the potential for development of dry eye, said Eric Perez-Campagne, MD. (Source: Modern Medicine)

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Moderate weight loss prevents incontinence in overweight diabetics

Modern Medicine — Wed, 08 Feb 2012 05:00:00 +0100

Overweight women with diabetes can cut their risk of developing urinary incontinence (UI) by shedding 5% to 10% of their body weight or as little as 15 lbs (7.7 kg), according to findings from the Look AHEAD trial, a multicenter, randomized, controlled trial of overweight and obese individuals with type 2 diabetes. (Source: Modern Medicine)

Efficacy of Vitamin D Supplementation in Multiple Sclerosis (EVIDIMS Trial): study protocol for a randomized controlled trial

Trials — Wed, 08 Feb 2012 05:00:00 +0100

DiscussionIn light of the discrepancy between existing epidemiological and preclinical data on the one hand and available clinical data on the other the EVIDIMS trial will substantially contribute to the evaluation of the efficacy of high-dose vitamin D supplementation in MS patients. The study design presented here fulfills the criteria of a high-quality clinical phase II trial in MS.Trial Registration: ClinicalTrials.gov Identifier: NCT01440062 (Source: Trials)

Breathe Easier Online: Evaluation of a Randomized Controlled Pilot Trial of an Internet-Based Intervention to Improve Well-being in Children and Adolescents With a Chronic Respiratory Condition

Journal of Medical Internet Research — Wed, 08 Feb 2012 05:00:00 +0100

Conclusions: Although there were no significant group differences on primary outcome measures, our pilot data provide tentative support for the feasibility (acceptability and user satisfaction) and initial efficacy of an Internet-based intervention for improving well-being in children and adolescents with a chronic respiratory condition. Trial registration: Australian New Zealand Clinical Trials Registry number: ACTRN12610000214033; http://www.anzctr.org.au/trial_view.aspx?ID=308074 (Archived by WebCite at http://www.webcitation.org/63BL55mXH) (Source: Journal of Medical Internet Research)

Does place of residence affect risk of suicide? A spatial epidemiologic investigation in Kentucky from 1999 to 2008

BioMed Central — Wed, 08 Feb 2012 05:00:00 +0100

Conclusions: Statistically significant high-risk spatial clusters of suicide were detected at the county level. This study may be useful for guiding future research and intervention efforts. Future studies will need to focus on these high-risk clusters to investigate reasons for these occurrences. (Source: BioMed Central)

Cervical cancer cell lines expressing NKG2D-ligands are able to down-modulate the NKG2D receptor on NKL cells with functional implications

BioMed Central — Wed, 08 Feb 2012 05:00:00 +0100

Conclusions: Our results suggest that differential expression of NKG2D-ligands in cervical cancer cell lines might be associated with the down-modulation of NKG2D, as well as with changes in the cytotoxic activity of NKL cells after cell-cell contact with the tumor cells. (Source: BioMed Central)

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Lipid raft/caveolae signaling is required for Cryptococcus neoformans invasion into human brain microvascular endothelial cells

BioMed Central — Wed, 08 Feb 2012 05:00:00 +0100

Conclusion: These data support that C. neoformans internalization into HBMEC is a lipid raft/caveolae-dependent endocytic process where the actin cytoskeleton is involved, and the Cav1 plays an essential role in C. neoformans traversal of the blood-brain barrier. (Source: BioMed Central)

Extracellular matrix alterations in experimental Leishmania amazonensis infection in susceptible and resistant mice

BioMed Central — Wed, 08 Feb 2012 05:00:00 +0100

Leishmania is inoculated, by the bite of an infected sandfly, into the skin of the host, where the promastigotes are phagocyted by dermal macrophages. The dermal region comprises cells and abundant extracellular matrix. Studies show that matrix metalloproteinases play an important role in host defense responses against pathogens in mammals and that their activities lead to the production of antimicrobial peptides. The aim of this study is to evaluate the changes in the distribution of fibronectin and laminin as well as in the elastic system fibres during the course of infection caused by Leishmania amazonensis in mice with distinct genetic backgrounds of susceptibility to this parasite. The results showed that BALB/c presented an enhancement of fibronectin during the course of infection wh...

Correction: Screening and control of methicillin-resistant Staphylococcus aureus in 186 intensive care units: different situations and individual solutions

BioMed Central — Wed, 08 Feb 2012 05:00:00 +0100

Following publication of our article [1], Dr Christine Geffers has been removed as co-author. (Source: BioMed Central)

A handoff is not a telegram: an understanding of the patient is co-constructed

BioMed Central — Wed, 08 Feb 2012 05:00:00 +0100

Hospital handoffs are believed to be a key locus of communication breakdown that can endanger patient safety and undermine quality of care. Substantial new efforts to better understand handoffs and to improve handoff practices are under way. Many such efforts appear to be seriously hampered, however, by an underlying presumption that the essential function of a handoff is one-way information transmission. Here, we examine social science literature that supports a richer framing of handoff conversations, one that characterizes them as co-constructions of an understanding of the patient. (Source: BioMed Central)

Clinical review: Sepsis and septic shock - the potential of gene arrays

BioMed Central — Wed, 08 Feb 2012 05:00:00 +0100

Over the past decade several investigators have applied microarray technology and related bioinformatic approaches to clinical sepsis and septic shock, thus allowing for an assessment of how, or if, this branch of genomic medicine has meaningfully impacted the field of sepsis research. The ability to simultaneously and efficiently measure the steady-state mRNA abundance of thousands of transcripts from a given tissue source (that is, 'transcriptomics') has provided an unprecedented opportunity to gain a broader, genome-level 'picture' of complex and heterogeneous clinical syndromes such as sepsis. A trancriptomic approach to sepsis and septic shock is technically challenging on multiple levels, but nonetheless modest, tangible advances are being realized. These include a genome-level under...

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Inflammasome and caspase-1 inhibition caused by Bcl-2 and Bcl-XL may influence cytokine responses of lipopolysaccharide-stimulated peripheral blood mononuclear cells from septic patients

BioMed Central — Wed, 08 Feb 2012 05:00:00 +0100

no abstract available. (Source: BioMed Central)

Recent biomarkers for the identification of patients at risk for preeclampsia: the role of uteroplacental ischemia

Expert Opinion: Expert Opinion on Medical Diagnostics — Wed, 08 Feb 2012 04:05:09 +0100

Expert Opinion on Medical Diagnostics, Volume 0, Issue 0, Page 1-10, Early Online. (Source: Expert Opinion: Expert Opinion on Medical Diagnostics)

Meningitis in Children

eMedicineHealth.com — Tue, 07 Feb 2012 07:00:00 +0100

(Source: eMedicineHealth.com)

Does Online Dating Make You Luckier at Love?

eMedicineHealth.com — Tue, 07 Feb 2012 07:00:00 +0100

(Source: eMedicineHealth.com)

Teens Exposed to Less Secondhand Smoke in Cars

eMedicineHealth.com — Tue, 07 Feb 2012 07:00:00 +0100

(Source: eMedicineHealth.com)

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Hard-Boiled Egg Recall Hits 34 States

eMedicineHealth.com — Tue, 07 Feb 2012 07:00:00 +0100

(Source: eMedicineHealth.com)

Heart Hormone Linked to Calorie-Burning Brown Fat

eMedicineHealth.com — Tue, 07 Feb 2012 07:00:00 +0100

(Source: eMedicineHealth.com)

School Vending Machines Still Offer Too Many Sugary Snacks

eMedicineHealth.com — Tue, 07 Feb 2012 07:00:00 +0100

(Source: eMedicineHealth.com)

Smoking in Men Speeds Up Mental Decline

eMedicineHealth.com — Tue, 07 Feb 2012 07:00:00 +0100

(Source: eMedicineHealth.com)

Kids Who Feel Left Out Are Less Active

eMedicineHealth.com — Tue, 07 Feb 2012 07:00:00 +0100

(Source: eMedicineHealth.com)

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Management and outcome of severely elevated blood pressure in primary care: A prospective observational study.

Swiss Medical Weekly — Tue, 07 Feb 2012 05:36:02 +0100

CONCLUSION: The majority of 164 patients who presented with acutely and severely elevated blood pressure (BP >180 +/or >110 mm Hg) to their GPs was asymptomatic, had pre-existing hypertension and was managed in GP's office unless a hypertensive emergency was present. At three month follow-up mean systolic BP was still above target values. PMID: 22287296 [PubMed - in process] (Source: Swiss Medical Weekly)

Blood pressure measurement - an overview.

Swiss Medical Weekly — Tue, 07 Feb 2012 05:36:02 +0100

This article provides an overview of current methods and trends in the field of non-invasive blood pressure measurement, an update on current clinical guidelines and an overview of blood pressure measurement in special populations. PMID: 22287317 [PubMed - in process] (Source: Swiss Medical Weekly)

Colonisation with Pseudomonas aeruginosa and antibiotic resistance patterns in COPD patients.

Swiss Medical Weekly — Tue, 07 Feb 2012 05:36:02 +0100

CONCLUSIONS: Colonisation with P. aeruginosa was present in all COPD severity stages and colonisation with mucoid strains was more frequent in advanced COPD. Resistance to the only oral anti-pseudomonas antibiotic ciprofloxacin was more frequently encountered in severe COPD stages. PMID: 22290607 [PubMed - in process] (Source: Swiss Medical Weekly)

Diagnosis and treatment of diffuse large B-cell lymphoma.

Swiss Medical Weekly — Tue, 07 Feb 2012 05:36:02 +0100

Authors: Mey U, Hitz F, Lohri A, Pederiva S, Taverna C, Tzankov A, Meier O, Yeow K, Renner C Abstract Diffuse large B-cell lymphoma (DLBCL) is the most frequently-occurring type of malignant lymphoma in the Western world. It has an aggressive natural history, with a median survival of less than one year if left untreated. Immunochemotherapy regimens, consisting of the anti-CD20 antibody rituximab typically in combination with cyclophosphamide, doxorubicin, vincristine and prednisone (CHOP), are currently the treatment backbone. Despite remarkable progress in improving patient survival, clinical outcomes are still unsatisfactory for certain subsets of patients, including the elderly and very elderly and those with highly aggressive disease. This review outlines some of the current ...

Editorial for issue 1 of 2012, Journal of evidence based medicine

Journal of Evidence-Based Medicine — Tue, 07 Feb 2012 05:00:00 +0100

(Source: Journal of Evidence-Based Medicine)

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Education section‐Studies within a trial (SWAT)

Journal of Evidence-Based Medicine — Tue, 07 Feb 2012 05:00:00 +0100

(Source: Journal of Evidence-Based Medicine)

Exercise interventions for smoking cessation

Journal of Evidence-Based Medicine — Tue, 07 Feb 2012 05:00:00 +0100

(Source: Journal of Evidence-Based Medicine)

Disposable surgical face masks for preventing surgical wound infection in clean surgery

Journal of Evidence-Based Medicine — Tue, 07 Feb 2012 05:00:00 +0100

(Source: Journal of Evidence-Based Medicine)

NACDS Foundation awards 58 scholarships, plans $750,000 more in grants

Modern Medicine — Tue, 07 Feb 2012 05:00:00 +0100

The National Association of Chain Drug Stores (NACDS) Foundation has awarded 58 scholarships – totaling $190,000 – to pharmacy schools representing 42 colleges and schools of pharmacy, the foundation announced. (Source: Modern Medicine)

Cardinal gets temporary restraining order to halt DEA’s suspension of Florida distribution center

Modern Medicine — Tue, 07 Feb 2012 05:00:00 +0100

Cardinal Health has requested a temporary restraining order to block a Drug Enforcement Administration suspension halting controlled-substance shipments from its Lakeland, Fla., distribution center. DEA suspended Cardinal’s distribution license for the Lakeland facility last Friday. (Source: Modern Medicine)

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FDA grants priority review to GI agent for controlling diarrhea in HIV/AIDS patients

Modern Medicine — Tue, 07 Feb 2012 05:00:00 +0100

FDA has granted priority review to crofelemer 125-mg tablets (Salix Pharmaceuticals) for the control and symptomatic relief of diarrhea in patients with HIV/AIDS on anti-retroviral therapy (ART). (Source: Modern Medicine)

Report: Drug costs to rise 3% to 5% this year

Modern Medicine — Tue, 07 Feb 2012 05:00:00 +0100

U.S. drug expenditures remained relatively flat in 2011, but a new report projects that drug costs will rise between 3% and 5% across all healthcare settings this year. . (Source: Modern Medicine)

Walgreens paying $225 million for parts of BioScrip’s business

Modern Medicine — Tue, 07 Feb 2012 05:00:00 +0100

Walgreens is acquiring “certain assets” of BioScrip’s community specialty pharmacies, centralized specialty, and mail service pharmacy businesses for approximately $225 million (Source: Modern Medicine)

NACDS tells Congress its concern about track-and-trace programs

Modern Medicine — Tue, 07 Feb 2012 05:00:00 +0100

The National Association of Chain Drug Stores (NACDS) expressed its concerns about proposed mandatory prescription track-and-trace programs in comments to a Congressional advisory panel recently. (Source: Modern Medicine)

Study: OTC medications save billions for healthcare system

Modern Medicine — Tue, 07 Feb 2012 05:00:00 +0100

The U.S. healthcare system saves $6 to $7 for every dollar Americans spend on over-the-counter medications, according to a new study released by the Consumer Healthcare Products Association recently. (Source: Modern Medicine)

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MAVIDOS Maternal Vitamin D Osteoporosis Study: study protocol for a randomized controlled trial.

Trials — Tue, 07 Feb 2012 05:00:00 +0100

In this study we aim to test whether offspring of mothers supplemented with vitamin D in pregnancy have higher bone mass at birth than those whose mothers were not supplemented. Methods: Women have their vitamin D status assessed after ultrasound scanning in the twelfth week of pregnancy at 3 trial centres (Southampton, Sheffield, Oxford). Women with circulating 25(OH)-vitamin D levels 25-100nmol/l are randomised in a double-blind design to either oral vitamin D supplement (1000 IU cholecalciferol/day, n=477) or placebo at 14 weeks (n=477). Questionnaire data include parity, sunlight exposure, dietary information, and cigarette and alcohol consumption. At 19 and 34 weeks maternal anthropometry is assessed and blood samples taken to measure 25(OH)-vitamin D, PTH and biochemistry. At deliver...

Development of a clinical trial to determine whether watchful waiting is an acceptable alternative to surgical repair for patients with oligosymptomatic incisional hernia: study protocol for a randomized controlled trial

Trials — Tue, 07 Feb 2012 05:00:00 +0100

This article describes the development of a prospective randomized clinical trial designed to determine whether watchful waiting is an acceptable alternative to surgical repair for patients with oligosymptomatic incisional hernia.Methods/ Design: This clinical multicenter trial has been designed to compare watchful waiting and surgical repair for patients with oligosymptomatic incisional hernia. Participants are randomized to watchful waiting or surgery and followed up for two years. The primary efficacy endpoint is pain/discomfort during normal activities as a result of the hernia or hernia repair two years after enrolment, as measured by the hernia-specific Surgical Pain Scales (SPS). The target sample size of six hundred thirty-six patients was calculated to detect non-inferiority of th...

Interpreting the Outcomes of Automated Internet-Based Randomized Trials: Example of an International Smoking Cessation Study

Journal of Medical Internet Research — Tue, 07 Feb 2012 05:00:00 +0100

Conclusions: Internet-based smoking cessation interventions can help large numbers of smokers quit. Large-scale international outcome studies can be successfully implemented using automated Internet sites. Interpretation of the studies’ results can be aided by extrapolating from results obtained from subsamples that are followed up by phone or similar cohort maintenance methods. Trial Registration: ClinicalTrials.gov NCT00721786; http://clinicaltrials.gov/ct2/show/NCT00721786 (Archived by WebCite at http://www.webcitation.org/63mhoXYPw) (Source: Journal of Medical Internet Research)

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